TreeWAS – Variant ID: rs6724422

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K83 Other diseases of biliary tract	0.418	0.582	0.000
K83.0 Cholangitis	0.410	0.590	0.000
K83.8 Other specified diseases of biliary tract	0.400	0.600	0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.391	0.609	0.000
K82 Other diseases of gallbladder	0.383	0.617	0.000
K83.1 Obstruction of bile duct	0.375	0.625	0.000
K86 Other diseases of pancreas	0.374	0.626	0.000
K86.2 Cyst of pancreas	0.356	0.644	0.000
K83.9 Disease of biliary tract, unspecified	0.337	0.663	0.000
K82.2 Perforation of gallbladder	0.334	0.666	0.000
K82.4 Cholesterolosis of gallbladder	0.331	0.669	0.000
K82.3 Fistula of gallbladder	0.318	0.682	0.000
K82.9 Disease of gallbladder, unspecified	0.316	0.684	0.000
K86.3 Pseudocyst of pancreas	0.308	0.692	0.000
K82.8 Other specified diseases of gallbladder	0.300	0.700	0.000
K83.5 Biliary cyst	0.300	0.700	0.000
K83.4 Spasm of sphincter of Oddi	0.300	0.700	0.000
K83.3 Fistula of bile duct	0.300	0.700	0.000
K83.2 Perforation of bile duct	0.300	0.700	0.000
K85 Acute pancreatitis	0.294	0.705	0.000
K86.9 Disease of pancreas, unspecified	0.290	0.710	0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.281	0.719	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.280	0.720	0.000
K82.0 Obstruction of gallbladder	0.275	0.725	0.000
K82.1 Hydrops of gallbladder	0.269	0.731	0.000
K86.8 Other specified diseases of pancreas	0.265	0.735	0.000
K81 Cholecystitis	0.265	0.735	0.000
K81.0 Acute cholecystitis	0.253	0.747	0.000
K85.9 Acute pancreatitis, unspecified	0.239	0.761	0.000
K86.1 Other chronic pancreatitis	0.219	0.781	0.000
K85.8 Other acute pancreatitis	0.211	0.789	0.000
K85.3 Drug-induced acute pancreatitis	0.211	0.789	0.000
K85.2 Alcohol-induced acute pancreatitis	0.211	0.789	0.000
K85.0 Idiopathic acute pancreatitis	0.211	0.789	0.000
K87.1 Disorders of pancreas in diseases classified elsewhere	0.201	0.798	0.000
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere	0.201	0.798	0.000
K81.8 Other cholecystitis	0.190	0.809	0.000
K85.1 Biliary acute pancreatitis	0.190	0.810	0.000
K81.9 Cholecystitis, unspecified	0.094	0.906	0.000
K81.1 Chronic cholecystitis	0.033	0.966	0.001
C50.1 Central portion of breast	0.000	0.982	0.018
C50 Malignant neoplasm of breast	0.000	0.984	0.016
C50.3 Lower-inner quadrant of breast	0.000	0.984	0.016
C50.4 Upper-outer quadrant of breast	0.000	0.985	0.015
C50.8 Overlapping lesion of breast	0.000	0.986	0.014
K80 Cholelithiasis	0.013	0.987	0.000
C50.0 Nipple and areola	0.000	0.988	0.012
C50.6 Axillary tail of breast	0.000	0.990	0.010
C50.2 Upper-inner quadrant of breast	0.000	0.990	0.010
E78.5 Hyperlipidaemia, unspecified	0.000	0.990	0.010
C50.9 Breast, unspecified	0.000	0.990	0.010
K80.3 Calculus of bile duct with cholangitis	0.009	0.991	0.000
E87.2 Acidosis	0.000	0.991	0.009
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.991	0.009
K80.8 Other cholelithiasis	0.009	0.991	0.000
E70-E90 Metabolic disorders	0.000	0.991	0.009
K80.4 Calculus of bile duct with cholecystitis	0.009	0.991	0.000
E88 Other metabolic disorders	0.000	0.991	0.009
E89.0 Postprocedural hypothyroidism	0.000	0.991	0.009
M20.5 Other deformities of toe(s) (acquired)	0.000	0.991	0.009
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.991	0.009
Z85.4 Personal history of malignant neoplasm of genital organs	0.000	0.991	0.009
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.991	0.009
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.991	0.009
E80.4 Gilbert's syndrome	0.000	0.992	0.008
C50.5 Lower-outer quadrant of breast	0.000	0.992	0.008
E83 Disorders of mineral metabolism	0.000	0.992	0.008
J33.8 Other polyp of sinus	0.007	0.993	0.000
N13.3 Other and unspecified hydronephrosis	0.000	0.993	0.007
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction	0.007	0.993	0.000
E83.3 Disorders of phosphorus metabolism	0.000	0.993	0.007
E89.3 Postprocedural hypopituitarism	0.000	0.993	0.007
J43.9 Emphysema, unspecified	0.007	0.993	0.000
C50-C50 Malignant neoplasm of breast	0.000	0.993	0.007
E85 Amyloidosis	0.000	0.993	0.007
E84 Cystic fibrosis	0.000	0.993	0.007
E79 Disorders of purine and pyrimidine metabolism	0.000	0.993	0.007
E77 Disorders of glycoprotein metabolism	0.000	0.993	0.007
E76 Disorders of glycosaminoglycan metabolism	0.000	0.993	0.007
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.993	0.007
E74 Other disorders of carbohydrate metabolism	0.000	0.993	0.007
E72 Other disorders of amino-acid metabolism	0.000	0.993	0.007
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.993	0.007
E70 Disorders of aromatic amino-acid metabolism	0.000	0.993	0.007
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.993	0.007
E88.9 Metabolic disorder, unspecified	0.000	0.993	0.007
E88.8 Other specified metabolic disorders	0.000	0.993	0.007
E88.3 Tumour lysis syndrome	0.000	0.993	0.007
E88.2 Lipomatosis, not elsewhere classified	0.000	0.993	0.007
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.993	0.007
E73 Lactose intolerance	0.000	0.993	0.007
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.993	0.007
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.993	0.007
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.993	0.007
E89.5 Postprocedural testicular hypofunction	0.000	0.993	0.007
E89.4 Postprocedural ovarian failure	0.000	0.993	0.007
E89.1 Postprocedural hypoinsulinaemia	0.000	0.993	0.007
E78.4 Other hyperlipidaemia	0.000	0.993	0.007
E87 Other disorders of fluid, electrolyte and acid-base balance	0.000	0.993	0.007
E78.2 Mixed hyperlipidaemia	0.000	0.993	0.006
E78.6 Lipoprotein deficiency	0.000	0.993	0.006
E78.3 Hyperchylomicronaemia	0.000	0.993	0.006
E78.1 Pure hyperglyceridaemia	0.000	0.993	0.006
E89.2 Postprocedural hypoparathyroidism	0.000	0.994	0.006
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.994	0.006
E80.6 Other disorders of bilirubin metabolism	0.000	0.994	0.006
E80.5 Crigler-Najjar syndrome	0.000	0.994	0.006
E80.3 Defects of catalase and peroxydase	0.000	0.994	0.006
E80.2 Other porphyria	0.000	0.994	0.006
E80.1 Porphyria cutanea tarda	0.000	0.994	0.006
E80.0 Hereditary erythropoietic porphyria	0.000	0.994	0.006
E83.4 Disorders of magnesium metabolism	0.000	0.994	0.006
E78.8 Other disorders of lipoprotein metabolism	0.000	0.994	0.006
E87.7 Fluid overload	0.000	0.994	0.006
N13 Obstructive and reflux uropathy	0.000	0.994	0.006
N83.2 Other and unspecified ovarian cysts	0.000	0.994	0.006
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.994	0.006
E83.8 Other disorders of mineral metabolism	0.000	0.994	0.006
E83.2 Disorders of zinc metabolism	0.000	0.994	0.006
E83.0 Disorders of copper metabolism	0.000	0.994	0.006
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.994	0.005
E83.5 Disorders of calcium metabolism	0.000	0.994	0.005
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.995	0.005
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.995	0.005
E70.3 Albinism	0.000	0.995	0.005
E70.2 Disorders of tyrosine metabolism	0.000	0.995	0.005
E70.1 Other hyperphenylalaninaemias	0.000	0.995	0.005
E70.0 Classical phenylketonuria	0.000	0.995	0.005
E71.3 Disorders of fatty-acid metabolism	0.000	0.995	0.005
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.995	0.005
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.995	0.005
E71.0 Maple-syrup-urine disease	0.000	0.995	0.005
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.995	0.005
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.995	0.005
E72.5 Disorders of glycine metabolism	0.000	0.995	0.005
E72.4 Disorders of ornithine metabolism	0.000	0.995	0.005
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.995	0.005
E72.2 Disorders of urea cycle metabolism	0.000	0.995	0.005
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.995	0.005
E72.0 Disorders of amino-acid transport	0.000	0.995	0.005
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.995	0.005
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.995	0.005
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.995	0.005
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.995	0.005
E74.2 Disorders of galactose metabolism	0.000	0.995	0.005
E74.1 Disorders of fructose metabolism	0.000	0.995	0.005
E74.0 Glycogen storage disease	0.000	0.995	0.005
E75.6 Lipid storage disorder, unspecified	0.000	0.995	0.005
E75.5 Other lipid storage disorders	0.000	0.995	0.005
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.995	0.005
E75.3 Sphingolipidosis, unspecified	0.000	0.995	0.005
E75.2 Other sphingolipidosis	0.000	0.995	0.005
E75.1 Other gangliosidosis	0.000	0.995	0.005
E75.0 GM2 gangliosidosis	0.000	0.995	0.005
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.995	0.005
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.995	0.005
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.995	0.005
E76.2 Other mucopolysaccharidoses	0.000	0.995	0.005
E76.1 Mucopolysaccharidosis, type II	0.000	0.995	0.005
E76.0 Mucopolysaccharidosis, type I	0.000	0.995	0.005
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.995	0.005
E77.8 Other disorders of glycoprotein metabolism	0.000	0.995	0.005
E77.1 Defects in glycoprotein degradation	0.000	0.995	0.005
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.995	0.005
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.995	0.005
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.995	0.005
E79.1 Lesch-Nyhan syndrome	0.000	0.995	0.005
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.995	0.005
E84.9 Cystic fibrosis, unspecified	0.000	0.995	0.005
E84.8 Cystic fibrosis with other manifestations	0.000	0.995	0.005
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.995	0.005
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.995	0.005
E85.9 Amyloidosis, unspecified	0.000	0.995	0.005
E85.8 Other amyloidosis	0.000	0.995	0.005
E85.4 Organ-limited amyloidosis	0.000	0.995	0.005
E85.3 Secondary systemic amyloidosis	0.000	0.995	0.005
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.995	0.005
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.995	0.005
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.995	0.005
D12.4 Descending colon	0.005	0.995	0.000
E73.8 Other lactose intolerance	0.000	0.995	0.005
E73.1 Secondary lactase deficiency	0.000	0.995	0.005
E73.0 Congenital lactase deficiency	0.000	0.995	0.005
E87.4 Mixed disorder of acid-base balance	0.000	0.995	0.005
N13.8 Other obstructive and reflux uropathy	0.000	0.995	0.005
E87.3 Alkalosis	0.000	0.995	0.005
N13.4 Hydroureter	0.000	0.995	0.005
E73.9 Lactose intolerance, unspecified	0.000	0.995	0.005
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.000	0.995	0.005
N13.9 Obstructive and reflux uropathy, unspecified	0.000	0.995	0.005
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.005	0.995	0.000
J02.9 Acute pharyngitis, unspecified	0.000	0.995	0.005
N13.7 Vesicoureteral-reflux-associated uropathy	0.000	0.995	0.004
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.000	0.995	0.004
E78.0 Pure hypercholesterolaemia	0.000	0.995	0.005
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.000	0.995	0.004
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.004	0.996	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.004	0.996	0.000
N13.6 Pyonephrosis	0.000	0.996	0.004
M54.57 Low back pain (Lumbosacral region)	0.000	0.996	0.004
N13.5 Kinking and stricture of ureter without hydronephrosis	0.000	0.996	0.004
M54.56 Low back pain (Lumbar region)	0.000	0.996	0.004
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.000	0.996	0.004
E86 Volume depletion	0.000	0.996	0.004
S30.0 Contusion of lower back and pelvis	0.004	0.996	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.004	0.996	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.004	0.996	0.000
M54.5 Low back pain	0.000	0.996	0.004
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.004	0.996	0.000
R22.4 Localised swelling, mass and lump, lower limb	0.000	0.996	0.004
S39.0 Injury of muscle and tendon of abdomen, lower back and pelvis	0.004	0.996	0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.004	0.996	0.000
S30.2 Contusion of external genital organs	0.003	0.996	0.000
S31 Open wound of abdomen, lower back and pelvis	0.003	0.996	0.000
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.003	0.997	0.000
S32 Fracture of lumbar spine and pelvis	0.003	0.997	0.000
E83.1 Disorders of iron metabolism	0.000	0.997	0.003
S30.1 Contusion of abdominal wall	0.003	0.997	0.000
S32.5 Fracture of pubis	0.003	0.997	0.000
S32.50 Fracture of pubis (closed)	0.003	0.997	0.000
E87.5 Hyperkalaemia	0.000	0.997	0.003
S37 Injury of urinary and pelvic organs	0.003	0.997	0.000
M54.59 Low back pain (Site unspecified)	0.000	0.997	0.003
G95.2 Cord compression, unspecified	0.003	0.997	0.000
S31.4 Open wound of vagina and vulva	0.003	0.997	0.000
D11.0 Parotid gland	0.003	0.997	0.000
Z85 Personal history of malignant neoplasm	0.000	0.997	0.003
E87.0 Hyperosmolality and hypernatraemia	0.000	0.997	0.003
S39.8 Other specified injuries of abdomen, lower back and pelvis	0.003	0.997	0.000
S39.7 Other multiple injuries of abdomen, lower back and pelvis	0.003	0.997	0.000
S39.6 Injury of intra-abdominal organ(s) with pelvic organ(s)	0.003	0.997	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.003	0.997	0.000
S36 Injury of intra-abdominal organs	0.003	0.997	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.003	0.997	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.003	0.997	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.003	0.997	0.000
M54.50 Low back pain (Multiple sites in spine)	0.000	0.997	0.003
S32.1 Fracture of sacrum	0.003	0.997	0.000
Z85.9 Personal history of malignant neoplasm, unspecified	0.000	0.997	0.003
N10-N16 Renal tubulo-interstitial diseases	0.000	0.997	0.003
M54.54 Low back pain-Thoracic	0.000	0.997	0.003
M54.53 Low back pain-Cervicothoracic	0.000	0.997	0.003
M54.52 Low back pain-Cervical	0.000	0.997	0.003
M54.51 Low back pain-Occipit-atl-axl	0.000	0.997	0.003
J43 Emphysema	0.003	0.997	0.000
S31.1 Open wound of abdominal wall	0.003	0.997	0.000
Z85.3 Personal history of malignant neoplasm of breast	0.000	0.997	0.003
S32.3 Fracture of ilium	0.003	0.997	0.000
S31.8 Open wound of other and unspecified parts of abdomen	0.003	0.997	0.000
S31.7 Multiple open wounds of abdomen, lower back and pelvis	0.003	0.997	0.000
S31.5 Open wound of other and unspecified external genital organs	0.003	0.997	0.000
S31.3 Open wound of scrotum and testes	0.003	0.997	0.000
S31.2 Open wound of penis	0.003	0.997	0.000
S31.0 Open wound of lower back and pelvis	0.003	0.997	0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.000	0.997	0.003
M54.55 Low back pain (Thoracolumbar region)	0.000	0.997	0.003
S32.10 Fracture of sacrum (closed)	0.003	0.997	0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung	0.000	0.997	0.003
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.003	0.997	0.000
S32.2 Fracture of coccyx	0.003	0.997	0.000
J02 Acute pharyngitis	0.000	0.997	0.003
S37.0 Injury of kidney	0.003	0.997	0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems	0.000	0.997	0.003
Z35.5 Supervision of elderly primigravida	0.003	0.997	0.000
Z51.2 Other chemotherapy	0.000	0.997	0.003
S32.51 Fracture of pubis (open)	0.002	0.997	0.000
E87.1 Hypo-osmolality and hyponatraemia	0.000	0.997	0.003
R14 Flatulence and related conditions	0.000	0.997	0.003
S32.0 Fracture of lumbar vertebra	0.003	0.997	0.000
K80.1 Calculus of gallbladder with other cholecystitis	0.003	0.997	0.000
S37.9 Injury of unspecified pelvic organ	0.002	0.997	0.000
S37.8 Injury of other pelvic organs	0.002	0.997	0.000
S37.7 Injury of multiple pelvic organs	0.002	0.997	0.000
S37.6 Injury of uterus	0.002	0.997	0.000
S37.5 Injury of Fallopian tube	0.002	0.997	0.000
S37.4 Injury of ovary	0.002	0.997	0.000
S37.3 Injury of urethra	0.002	0.997	0.000
S37.2 Injury of bladder	0.002	0.997	0.000
S37.1 Injury of ureter	0.002	0.997	0.000
N11 Chronic tubulo-interstitial nephritis	0.000	0.997	0.002
S42.00 Fracture of clavicle (closed)	0.003	0.997	0.000
Z85.0 Personal history of malignant neoplasm of digestive organs	0.000	0.997	0.002
I51.7 Cardiomegaly	0.003	0.997	0.000
S32.7 Multiple fractures of lumbar spine and pelvis	0.002	0.997	0.000
S33.7 Sprain and strain of other and unspecified parts of lumbar spine and pelvis	0.002	0.997	0.000
S33.6 Sprain and strain of sacro-iliac joint	0.002	0.997	0.000
S33.5 Sprain and strain of lumbar spine	0.002	0.997	0.000
S33.4 Traumatic rupture of symphysis pubis	0.002	0.997	0.000
S33.3 Dislocation of other and unspecified parts of lumbar spine and pelvis	0.002	0.997	0.000
S33.2 Dislocation of sacro-iliac and sacrococcygeal joint	0.002	0.997	0.000
S33.1 Dislocation of lumbar vertebra	0.002	0.997	0.000
S33.0 Traumatic rupture of lumbar intervertebral disk	0.002	0.997	0.000
S34.8 Injury of other and unspecified nerves at abdomen, lower back and pelvis level	0.002	0.997	0.000
S34.6 Injury of peripheral nerve(s) of abdomen, lower back and pelvis	0.002	0.997	0.000
S34.5 Injury of lumbar, sacral and pelvic sympathetic nerves	0.002	0.997	0.000
S34.4 Injury of lumbosacral plexus	0.002	0.997	0.000
S34.3 Injury of cauda equina	0.002	0.997	0.000
S34.2 Injury of nerve root of lumbar and sacral spine	0.002	0.997	0.000
S34.1 Other injury of lumbar spinal cord	0.002	0.997	0.000
S34.0 Concussion and oedema of lumbar spinal cord	0.002	0.997	0.000
S35.9 Injury of unspecified blood vessel at abdomen, lower back and pelvis level	0.002	0.997	0.000
S35.8 Injury of other blood vessels at abdomen, lower back and pelvis level	0.002	0.997	0.000
S35.7 Injury of multiple blood vessels at abdomen, lower back and pelvis level	0.002	0.997	0.000
S35.5 Injury of iliac blood vessels	0.002	0.997	0.000
S35.4 Injury of renal blood vessels	0.002	0.997	0.000
S35.3 Injury of portal or splenic vein	0.002	0.997	0.000
S35.2 Injury of coeliac or mesenteric artery	0.002	0.997	0.000
S35.1 Injury of inferior vena cava	0.002	0.997	0.000
S35.0 Injury of abdominal aorta	0.002	0.997	0.000
S36.9 Injury of unspecified intra-abdominal organ	0.002	0.997	0.000
S36.8 Injury of other intra-abdominal organs	0.002	0.997	0.000
S36.7 Injury of multiple intra-abdominal organs	0.002	0.997	0.000
S36.6 Injury of rectum	0.002	0.997	0.000
S36.5 Injury of colon	0.002	0.997	0.000
S36.4 Injury of small intestine	0.002	0.997	0.000
S36.3 Injury of stomach	0.002	0.997	0.000
S36.2 Injury of pancreas	0.002	0.997	0.000
S36.1 Injury of liver or gallbladder	0.002	0.997	0.000
S36.0 Injury of spleen	0.002	0.997	0.000
S38.3 Traumatic amputation of other and unspecified parts of abdomen, lower back and pelvis	0.002	0.997	0.000
S38.2 Traumatic amputation of external genital organs	0.002	0.997	0.000
S38.1 Crushing injury of other and unspecified parts of abdomen, lower back and pelvis	0.002	0.997	0.000
S38.0 Crushing injury of external genital organs	0.002	0.997	0.000
S32.4 Fracture of acetabulum	0.002	0.997	0.000
S32.11 Fracture of sacrum (open)	0.002	0.998	0.000
J43.8 Other emphysema	0.002	0.998	0.000
J43.2 Centrilobular emphysema	0.002	0.998	0.000
J43.1 Panlobular emphysema	0.002	0.998	0.000
J43.0 MacLeod's syndrome	0.002	0.998	0.000
Z85.6 Personal history of leukaemia	0.000	0.998	0.002
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.000	0.998	0.002
N15 Other renal tubulo-interstitial diseases	0.000	0.998	0.002
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.000	0.998	0.002
N10 Acute tubulo-interstitial nephritis	0.000	0.998	0.002
S32.30 Fracture of ilium (closed)	0.002	0.998	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.000	0.998	0.002
I42.0 Dilated cardiomyopathy	0.002	0.998	0.000
S37.00 Injury of kidney (without open wound into cavity)	0.002	0.998	0.000
G93.3 Postviral fatigue syndrome	0.000	0.998	0.002
S32.31 Fracture of ilium (open)	0.002	0.998	0.000
O70.0 First degree perineal laceration during delivery	0.000	0.998	0.002
T78.4 Allergy, unspecified	0.002	0.998	0.000
S32.21 Fracture of coccyx (open)	0.002	0.998	0.000
S32.20 Fracture of coccyx (closed)	0.002	0.998	0.000
S32.81 Fracture of other and unspecified parts of lumbar spine and pelvis (open)	0.002	0.998	0.000
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.000	0.998	0.002
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.002	0.998	0.000
J02.8 Acute pharyngitis due to other specified organisms	0.000	0.998	0.002
J02.0 Streptococcal pharyngitis	0.000	0.998	0.002
N60.1 Diffuse cystic mastopathy	0.000	0.998	0.002
S37.01 Injury of kidney (with open wound into cavity)	0.002	0.998	0.000
R22.9 Localised swelling, mass and lump, unspecified	0.000	0.998	0.002
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.002	0.998	0.000
R22.2 Localised swelling, mass and lump, trunk	0.000	0.998	0.002
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.000	0.998	0.002
S32.01 Fracture of lumbar vertebra (open)	0.002	0.998	0.000
S37.11 Injury of ureter (with open wound into cavity)	0.002	0.998	0.000
S37.10 Injury of ureter (without open wound into cavity)	0.002	0.998	0.000
S37.21 Injury of bladder (with open wound into cavity)	0.002	0.998	0.000
S37.20 Injury of bladder (without open wound into cavity)	0.002	0.998	0.000
S37.31 Injury of urethra (with open wound into cavity)	0.002	0.998	0.000
S37.30 Injury of urethra (without open wound into cavity)	0.002	0.998	0.000
S37.41 Injury of ovary (with open wound into cavity)	0.002	0.998	0.000
S37.40 Injury of ovary (without open wound into cavity)	0.002	0.998	0.000
S37.51 Injury of fallopian tube (with open wound into cavity)	0.002	0.998	0.000
S37.50 Injury of fallopian tube (without open wound into cavity)	0.002	0.998	0.000
S37.61 Injury of uterus (with open wound into cavity)	0.002	0.998	0.000
S37.60 Injury of uterus (without open wound into cavity)	0.002	0.998	0.000
S37.71 Injury of multiple pelvic organs (with open wound into cavity)	0.002	0.998	0.000
S37.70 Injury of multiple pelvic organs (without open wound into cavity)	0.002	0.998	0.000
S37.81 Injury of other pelvic organs (with open wound into cavity)	0.002	0.998	0.000
S37.80 Injury of other pelvic organs (without open wound into cavity)	0.002	0.998	0.000
S37.91 Injury of unspecified pelvic organ (with open wound into cavity)	0.002	0.998	0.000
S37.90 Injury of unspecified pelvic organ (without open wound into cavity)	0.002	0.998	0.000
N11.8 Other chronic tubulo-interstitial nephritis	0.000	0.998	0.002
N11.1 Chronic obstructive pyelonephritis	0.000	0.998	0.002
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.000	0.998	0.002
Z85.02 Personal history of malignant neoplasm of stomach	0.000	0.998	0.002
G95.1 Vascular myelopathies	0.002	0.998	0.000
G95 Other diseases of spinal cord	0.002	0.998	0.000
S32.71 Multiple fractures of lumbar spine and pelvis (open)	0.002	0.998	0.000
S36.01 Injury of spleen (with open wound into cavity)	0.002	0.998	0.000
S36.00 Injury of spleen (without open wound into cavity)	0.002	0.998	0.000
S36.11 Injury of liver or gallbladder (with open wound into cavity)	0.002	0.998	0.000
S36.10 Injury of liver or gallbladder (without open wound into cavity)	0.002	0.998	0.000
S36.21 Injury of pancreas (with open wound into cavity)	0.002	0.998	0.000
S36.20 Injury of pancreas (without open wound into cavity)	0.002	0.998	0.000
S36.31 Injury of stomach (with open wound into cavity)	0.002	0.998	0.000
S36.30 Injury of stomach (without open wound into cavity)	0.002	0.998	0.000
S36.41 Injury of small intestine (with open wound into cavity)	0.002	0.998	0.000
S36.40 Injury of small intestine (without open wound into cavity)	0.002	0.998	0.000
S36.51 Injury of colon (with open wound into cavity)	0.002	0.998	0.000
S36.50 Injury of colon (without open wound into cavity)	0.002	0.998	0.000
S36.61 Injury of rectum (with open wound into cavity)	0.002	0.998	0.000
S36.60 Injury of rectum (without open wound into cavity)	0.002	0.998	0.000
S36.71 Injury of multiple intra-abdominal organs (with open wound into cavity)	0.002	0.998	0.000
S36.70 Injury of multiple intra-abdominal organs (without open wound into cavity)	0.002	0.998	0.000
S36.81 Injury of other intra-abdominal organs (with open wound into cavity)	0.002	0.998	0.000
S36.80 Injury of other intra-abdominal organs (without open wound into cavity)	0.002	0.998	0.000
S36.91 Injury of unspecified intra-abdominal organ (with open wound into cavity)	0.002	0.998	0.000
S36.90 Injury of unspecified intra-abdominal organ (without open wound into cavity)	0.002	0.998	0.000
S32.41 Fracture of acetabulum (open)	0.002	0.998	0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues	0.000	0.998	0.002
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.002	0.998	0.000
N14.4 Toxic nephropathy, not elsewhere classified	0.000	0.998	0.002
N14.3 Nephropathy induced by heavy metals	0.000	0.998	0.002
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance	0.000	0.998	0.002
N14.1 Nephropathy induced by other drugs, medicaments and biological substances	0.000	0.998	0.002
N14.0 Analgesic nephropathy	0.000	0.998	0.002
N15.9 Renal tubulo-interstitial disease, unspecified	0.000	0.998	0.002
N15.8 Other specified renal tubulo-interstitial diseases	0.000	0.998	0.002
N15.1 Renal and perinephric abscess	0.000	0.998	0.002
N15.0 Balkan nephropathy	0.000	0.998	0.002
N16.8 Renal tubulo-interstitial disorders in other diseases classified elsewhere	0.000	0.998	0.002
N16.5 Renal tubulo-interstitial disorders in transplant rejection	0.000	0.998	0.002
N16.4 Renal tubulo-interstitial disorders in systemic connective tissue disorders	0.000	0.998	0.002
N16.3 Renal tubulo-interstitial disorders in metabolic diseases	0.000	0.998	0.002
N16.2 Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism	0.000	0.998	0.002
N16.1 Renal tubulo-interstitial disorders in neoplastic diseases	0.000	0.998	0.002
N16.0 Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
T78.1 Other adverse food reactions, not elsewhere classified	0.002	0.998	0.000
T78 Adverse effects, not elsewhere classified	0.002	0.998	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.002	0.998	0.000
M48.07 Spinal stenosis (Lumbosacral region)	0.002	0.998	0.000
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s	0.000	0.998	0.002
T78.2 Anaphylactic shock, unspecified	0.002	0.998	0.000
H50.0 Convergent concomitant strabismus	0.002	0.998	0.000
S32.00 Fracture of lumbar vertebra (closed)	0.002	0.998	0.000
E87.6 Hypokalaemia	0.000	0.998	0.002
I51.8 Other ill-defined heart diseases	0.002	0.998	0.000
K80.0 Calculus of gallbladder with acute cholecystitis	0.002	0.998	0.000
T78.3 Angioneurotic oedema	0.002	0.998	0.000
M06.4 Inflammatory polyarthropathy	0.002	0.998	0.000
G95.8 Other specified diseases of spinal cord	0.002	0.998	0.000
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.002	0.998	0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.002	0.998	0.000
R22.7 Localised swelling, mass and lump, multiple sites	0.000	0.998	0.002
Z35 Supervision of high-risk pregnancy	0.002	0.998	0.000
M19.01 Primary arthrosis of other joints (Shoulder region)	0.000	0.998	0.002
S42.0 Fracture of clavicle	0.002	0.998	0.000
I51 Complications and ill-defined descriptions of heart disease	0.002	0.998	0.000
N60 Benign mammary dysplasia	0.000	0.998	0.002
S32.40 Fracture of acetabulum (closed)	0.001	0.998	0.000
N60.3 Fibrosclerosis of breast	0.000	0.998	0.002
R29.6 Tendency to fall, not elsewhere classified	0.000	0.998	0.002
I51.4 Myocarditis, unspecified	0.002	0.998	0.000
G95.0 Syringomyelia and syringobulbia	0.002	0.998	0.000
T78.9 Adverse effect, unspecified	0.002	0.998	0.000
T78.8 Other adverse effects, not elsewhere classified	0.002	0.998	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.998	0.002
R04.2 Haemoptysis	0.002	0.998	0.000
B07 Viral warts	0.002	0.998	0.000
D05.1 Intraductal carcinoma in situ	0.000	0.998	0.002
N60.4 Mammary duct ectasia	0.000	0.998	0.002
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs	0.000	0.998	0.001
N63 Unspecified lump in breast	0.000	0.998	0.002
M06.48 Inflammatory polyarthropathy (Other)	0.001	0.998	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.001	0.998	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.001	0.998	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.001	0.998	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.001	0.998	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.001	0.998	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.001	0.998	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.001	0.998	0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.002	0.998	0.000
Z35.0 Supervision of pregnancy with history of infertility	0.002	0.998	0.000
A04.7 Enterocolitis due to Clostridium difficile	0.000	0.998	0.002
C34.0 Main bronchus	0.002	0.998	0.000
H50.1 Divergent concomitant strabismus	0.002	0.998	0.000
R22.3 Localised swelling, mass and lump, upper limb	0.000	0.998	0.001
R22.0 Localised swelling, mass and lump, head	0.000	0.998	0.002
Z35.9 Supervision of high-risk pregnancy, unspecified	0.001	0.998	0.000
Z35.7 Supervision of high-risk pregnancy due to social problems	0.001	0.998	0.000
Z35.6 Supervision of very young primigravida	0.001	0.998	0.000
Z35.4 Supervision of pregnancy with grand multiparity	0.001	0.998	0.000
Z35.3 Supervision of pregnancy with history of insufficient antenatal care	0.001	0.998	0.000
M48.09 Spinal stenosis (Site unspecified)	0.002	0.998	0.000
S42.01 Fracture of clavicle (open)	0.001	0.998	0.000
K50.0 Crohn's disease of small intestine	0.000	0.998	0.002
N60.0 Solitary cyst of breast	0.000	0.998	0.002
G95.9 Disease of spinal cord, unspecified	0.001	0.998	0.000
I51.6 Cardiovascular disease, unspecified	0.001	0.998	0.000
I51.5 Myocardial degeneration	0.001	0.998	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.001	0.998	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.001	0.998	0.000
N60.9 Benign mammary dysplasia, unspecified	0.000	0.998	0.001
D47.3 Essential (haemorrhagic) thrombocythaemia	0.001	0.998	0.000
Z99.2 Dependence on renal dialysis	0.000	0.998	0.002
I84.2 Internal haemorrhoids without complication	0.002	0.998	0.000
M54.39 Sciatica (Site unspecified)	0.001	0.998	0.000
Z35.8 Supervision of other high-risk pregnancies	0.001	0.998	0.000
H50 Other strabismus	0.002	0.998	0.000
M54.36 Sciatica (Lumbar region)	0.001	0.998	0.000
D47.1 Chronic myeloproliferative disease	0.001	0.998	0.000
Z71.8 Other specified counselling	0.001	0.998	0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances	0.002	0.998	0.000
D11 Benign neoplasm of major salivary glands	0.001	0.998	0.000
T78.0 Anaphylactic shock due to adverse food reaction	0.001	0.999	0.000
Z35.1 Supervision of pregnancy with history of abortive outcome	0.001	0.999	0.000
Z96.7 Presence of other bone and tendon implants	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations