TreeWAS – Variant ID: rs6742078

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E80.4 Gilbert's syndrome	1.000	0.000	0.000
K80.2 Calculus of gallbladder without cholecystitis	1.000	0.000	0.000
K80 Cholelithiasis	0.993	0.007	0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.991	0.009	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.813	0.187	0.000
K80.4 Calculus of bile duct with cholecystitis	0.807	0.193	0.000
K80.1 Calculus of gallbladder with other cholecystitis	0.781	0.219	0.000
E80.6 Other disorders of bilirubin metabolism	0.779	0.221	0.000
R17 Unspecified jaundice	0.776	0.224	0.000
K80.0 Calculus of gallbladder with acute cholecystitis	0.746	0.254	0.000
K80.3 Calculus of bile duct with cholangitis	0.712	0.288	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.583	0.417	0.000
E80.5 Crigler-Najjar syndrome	0.583	0.417	0.000
E80.3 Defects of catalase and peroxydase	0.583	0.417	0.000
E80.0 Hereditary erythropoietic porphyria	0.583	0.417	0.000
E80.1 Porphyria cutanea tarda	0.579	0.421	0.000
E80.2 Other porphyria	0.562	0.438	0.000
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction	0.510	0.489	0.000
L42 Pityriasis rosea	0.469	0.531	0.000
K80.8 Other cholelithiasis	0.397	0.603	0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.274	0.726	0.000
K81 Cholecystitis	0.261	0.739	0.000
K81.1 Chronic cholecystitis	0.248	0.752	0.000
K81.0 Acute cholecystitis	0.222	0.778	0.000
K85 Acute pancreatitis	0.214	0.786	0.000
K81.9 Cholecystitis, unspecified	0.205	0.795	0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.196	0.804	0.000
K85.1 Biliary acute pancreatitis	0.174	0.825	0.000
K85.2 Alcohol-induced acute pancreatitis	0.166	0.833	0.000
K85.8 Other acute pancreatitis	0.154	0.846	0.000
K85.3 Drug-induced acute pancreatitis	0.153	0.847	0.000
K85.0 Idiopathic acute pancreatitis	0.153	0.847	0.000
K87.1 Disorders of pancreas in diseases classified elsewhere	0.141	0.859	0.000
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere	0.141	0.859	0.000
K86 Other diseases of pancreas	0.133	0.867	0.000
K81.8 Other cholecystitis	0.130	0.869	0.000
K85.9 Acute pancreatitis, unspecified	0.128	0.872	0.000
K86.9 Disease of pancreas, unspecified	0.126	0.874	0.000
K86.3 Pseudocyst of pancreas	0.103	0.897	0.000
K86.2 Cyst of pancreas	0.077	0.923	0.000
L40-L45 Papulosquamous disorders	0.066	0.934	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.061	0.939	0.000
K83 Other diseases of biliary tract	0.061	0.939	0.000
K82 Other diseases of gallbladder	0.060	0.940	0.000
R94.5 Abnormal results of liver function studies	0.053	0.947	0.000
K86.8 Other specified diseases of pancreas	0.051	0.949	0.000
L44 Other papulosquamous disorders	0.048	0.952	0.000
L41 Parapsoriasis	0.048	0.952	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.048	0.952	0.000
K82.2 Perforation of gallbladder	0.046	0.954	0.000
K83.5 Biliary cyst	0.044	0.956	0.000
K83.4 Spasm of sphincter of Oddi	0.044	0.956	0.000
K83.2 Perforation of bile duct	0.044	0.956	0.000
K83.3 Fistula of bile duct	0.044	0.956	0.000
K82.0 Obstruction of gallbladder	0.041	0.959	0.000
R61.9 Hyperhidrosis, unspecified	0.000	0.959	0.041
K83.0 Cholangitis	0.041	0.959	0.000
K82.9 Disease of gallbladder, unspecified	0.040	0.960	0.000
K82.3 Fistula of gallbladder	0.039	0.961	0.000
K83.9 Disease of biliary tract, unspecified	0.039	0.961	0.000
K82.4 Cholesterolosis of gallbladder	0.038	0.962	0.000
L43 Lichen planus	0.037	0.963	0.000
L41.9 Parapsoriasis, unspecified	0.034	0.965	0.000
L41.8 Other parapsoriasis	0.034	0.965	0.000
L41.5 Retiform parapsoriasis	0.034	0.965	0.000
L41.4 Large plaque parapsoriasis	0.034	0.965	0.000
L41.3 Small plaque parapsoriasis	0.034	0.965	0.000
L41.2 Lymphomatoid papulosis	0.034	0.965	0.000
L41.1 Pityriasis lichenoides chronica	0.034	0.965	0.000
L41.0 Pityriasis lichenoides et varioliformis acuta	0.034	0.965	0.000
L44.9 Papulosquamous disorder, unspecified	0.034	0.965	0.000
L44.8 Other specified papulosquamous disorders	0.034	0.965	0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.034	0.965	0.000
L44.3 Lichen ruber moniliformis	0.034	0.965	0.000
L44.2 Lichen striatus	0.034	0.965	0.000
L44.1 Lichen nitidus	0.034	0.965	0.000
L44.0 Pityriasis rubra pilaris	0.034	0.965	0.000
K82.1 Hydrops of gallbladder	0.030	0.970	0.000
K83.8 Other specified diseases of biliary tract	0.029	0.971	0.000
L43.8 Other lichen planus	0.027	0.972	0.000
L43.3 Subacute (active) lichen planus	0.027	0.973	0.000
L43.2 Lichenoid drug reaction	0.027	0.973	0.000
L43.1 Bullous lichen planus	0.027	0.973	0.000
L43.0 Hypertrophic lichen planus	0.027	0.973	0.000
K86.1 Other chronic pancreatitis	0.026	0.974	0.000
I08.0 Disorders of both mitral and aortic valves	0.000	0.976	0.024
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.977	0.023
I08 Multiple valve diseases	0.000	0.977	0.023
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.980	0.020
I08.9 Multiple valve disease, unspecified	0.000	0.981	0.019
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.985	0.015
I05-I09 Chronic rheumatic heart diseases	0.000	0.985	0.015
R61 Hyperhidrosis	0.000	0.985	0.015
I05 Rheumatic mitral valve diseases	0.000	0.985	0.015
L43.9 Lichen planus, unspecified	0.014	0.986	0.000
I05.2 Mitral stenosis with insufficiency	0.000	0.986	0.014
L40 Psoriasis	0.014	0.986	0.000
K82.8 Other specified diseases of gallbladder	0.014	0.986	0.000
I05.9 Mitral valve disease, unspecified	0.000	0.988	0.012
I09 Other rheumatic heart diseases	0.000	0.989	0.011
I07 Rheumatic tricuspid valve diseases	0.000	0.989	0.011
R61.1 Generalised hyperhidrosis	0.000	0.989	0.011
L40.8 Other psoriasis	0.011	0.989	0.000
I05.1 Rheumatic mitral insufficiency	0.000	0.989	0.011
I08.8 Other multiple valve diseases	0.000	0.989	0.011
I05.8 Other mitral valve diseases	0.000	0.989	0.011
L40.3 Pustulosis palmaris et plantaris	0.011	0.989	0.000
L40.1 Generalised pustular psoriasis	0.011	0.989	0.000
I06 Rheumatic aortic valve diseases	0.000	0.990	0.010
L40.2 Acrodermatitis continua	0.010	0.990	0.000
I05.0 Mitral stenosis	0.000	0.990	0.010
R61.0 Localised hyperhidrosis	0.000	0.990	0.010
L40.4 Guttate psoriasis	0.009	0.990	0.000
L40.0 Psoriasis vulgaris	0.009	0.991	0.000
I09.8 Other specified rheumatic heart diseases	0.000	0.992	0.008
I09.2 Chronic rheumatic pericarditis	0.000	0.992	0.008
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.000	0.992	0.008
I09.0 Rheumatic myocarditis	0.000	0.992	0.008
Y79.2 Prosthetic and other implants, materials and accessory devices	0.008	0.992	0.000
I07.9 Tricuspid valve disease, unspecified	0.000	0.992	0.008
I07.8 Other tricuspid valve diseases	0.000	0.992	0.008
I07.2 Tricuspid stenosis with insufficiency	0.000	0.992	0.008
I07.0 Tricuspid stenosis	0.000	0.992	0.008
I09.9 Rheumatic heart disease, unspecified	0.000	0.992	0.008
I06.1 Rheumatic aortic insufficiency	0.000	0.992	0.008
D36.1 Peripheral nerves and autonomic nervous system	0.000	0.992	0.008
I07.1 Tricuspid insufficiency	0.000	0.992	0.008
I06.9 Rheumatic aortic valve disease, unspecified	0.000	0.992	0.008
I06.8 Other rheumatic aortic valve diseases	0.000	0.992	0.008
I06.2 Rheumatic aortic stenosis with insufficiency	0.000	0.992	0.008
K76.0 Fatty (change of) liver, not elsewhere classified	0.007	0.993	0.000
H81.1 Benign paroxysmal vertigo	0.000	0.993	0.007
I06.0 Rheumatic aortic stenosis	0.000	0.993	0.006
E70-E90 Metabolic disorders	0.007	0.993	0.000
K83.1 Obstruction of bile duct	0.006	0.994	0.000
R94 Abnormal results of function studies	0.006	0.994	0.000
M17.0 Primary gonarthrosis, bilateral	0.006	0.994	0.000
E84 Cystic fibrosis	0.006	0.994	0.000
E88 Other metabolic disorders	0.006	0.994	0.000
I38 Endocarditis, valve unspecified	0.000	0.995	0.005
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.005	0.995	0.000
R94.6 Abnormal results of thyroid function studies	0.005	0.995	0.000
E70 Disorders of aromatic amino-acid metabolism	0.005	0.995	0.000
Y79 Orthopaedic devices associated with adverse incidents	0.005	0.995	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.005	0.995	0.000
R94.4 Abnormal results of kidney function studies	0.005	0.995	0.000
E84.9 Cystic fibrosis, unspecified	0.005	0.995	0.000
E77 Disorders of glycoprotein metabolism	0.005	0.995	0.000
E76 Disorders of glycosaminoglycan metabolism	0.005	0.995	0.000
E74 Other disorders of carbohydrate metabolism	0.005	0.995	0.000
E72 Other disorders of amino-acid metabolism	0.005	0.995	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.005	0.995	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.005	0.995	0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses	0.005	0.995	0.000
M96.0 Pseudarthrosis after fusion or arthrodesis	0.000	0.995	0.005
R94.8 Abnormal results of function studies of other organs and systems	0.005	0.995	0.000
E79 Disorders of purine and pyrimidine metabolism	0.005	0.995	0.000
E70.3 Albinism	0.004	0.995	0.000
R52.0 Acute pain	0.000	0.995	0.005
E87.0 Hyperosmolality and hypernatraemia	0.004	0.996	0.000
R94.7 Abnormal results of other endocrine function studies	0.004	0.996	0.000
R94.0 Abnormal results of function studies of central nervous system	0.004	0.996	0.000
E88.8 Other specified metabolic disorders	0.004	0.996	0.000
E87.7 Fluid overload	0.004	0.996	0.000
E84.8 Cystic fibrosis with other manifestations	0.004	0.996	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.004	0.996	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.004	0.996	0.000
E88.9 Metabolic disorder, unspecified	0.004	0.996	0.000
E87.5 Hyperkalaemia	0.004	0.996	0.000
E88.2 Lipomatosis, not elsewhere classified	0.004	0.996	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.004	0.996	0.000
E88.3 Tumour lysis syndrome	0.004	0.996	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.004	0.996	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.004	0.996	0.000
E70.2 Disorders of tyrosine metabolism	0.004	0.996	0.000
E70.1 Other hyperphenylalaninaemias	0.004	0.996	0.000
E70.0 Classical phenylketonuria	0.004	0.996	0.000
E75.2 Other sphingolipidosis	0.004	0.996	0.000
Y79.3 Surgical instruments, materials and devices (including sutures)	0.004	0.996	0.000
R52.1 Chronic intractable pain	0.000	0.996	0.004
J13 Pneumonia due to Streptococcus pneumoniae	0.000	0.996	0.004
N99.3 Prolapse of vaginal vault after hysterectomy	0.004	0.996	0.000
E16.2 Hypoglycaemia, unspecified	0.004	0.996	0.000
Y79.8 Miscellaneous devices, not elsewhere classified	0.004	0.996	0.000
Y79.1 Therapeutic (nonsurgical) and rehabilitative devices	0.004	0.996	0.000
Y79.0 Diagnostic and monitoring devices	0.004	0.996	0.000
E73 Lactose intolerance	0.004	0.996	0.000
R52 Pain, not elsewhere classified	0.000	0.996	0.004
E75.6 Lipid storage disorder, unspecified	0.004	0.996	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.004	0.996	0.000
E75.3 Sphingolipidosis, unspecified	0.004	0.996	0.000
E75.1 Other gangliosidosis	0.004	0.996	0.000
E75.0 GM2 gangliosidosis	0.004	0.996	0.000
E75.5 Other lipid storage disorders	0.004	0.996	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.004	0.996	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.004	0.996	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.004	0.996	0.000
E74.2 Disorders of galactose metabolism	0.004	0.996	0.000
E74.1 Disorders of fructose metabolism	0.004	0.996	0.000
E74.0 Glycogen storage disease	0.004	0.996	0.000
E71.3 Disorders of fatty-acid metabolism	0.004	0.996	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.004	0.996	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.004	0.996	0.000
E71.0 Maple-syrup-urine disease	0.004	0.996	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.004	0.996	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.004	0.996	0.000
E72.5 Disorders of glycine metabolism	0.004	0.996	0.000
E72.4 Disorders of ornithine metabolism	0.004	0.996	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.004	0.996	0.000
E72.2 Disorders of urea cycle metabolism	0.004	0.996	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.004	0.996	0.000
E72.0 Disorders of amino-acid transport	0.004	0.996	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.004	0.996	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.004	0.996	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.004	0.996	0.000
E76.2 Other mucopolysaccharidoses	0.004	0.996	0.000
E76.1 Mucopolysaccharidosis, type II	0.004	0.996	0.000
E76.0 Mucopolysaccharidosis, type I	0.004	0.996	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.004	0.996	0.000
E77.8 Other disorders of glycoprotein metabolism	0.004	0.996	0.000
E77.1 Defects in glycoprotein degradation	0.004	0.996	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.004	0.996	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.004	0.996	0.000
R52.9 Pain, unspecified	0.000	0.996	0.004
Y53.1 Other antacids and anti-gastric-secretion drugs	0.004	0.996	0.000
R94.2 Abnormal results of pulmonary function studies	0.003	0.996	0.000
H81 Disorders of vestibular function	0.000	0.996	0.004
H81.2 Vestibular neuronitis	0.000	0.996	0.004
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.003	0.996	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.003	0.996	0.000
E79.1 Lesch-Nyhan syndrome	0.003	0.996	0.000
F52.2 Failure of genital response	0.004	0.996	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.003	0.996	0.000
E85 Amyloidosis	0.003	0.997	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.003	0.997	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.000	0.997	0.003
D18.0 Haemangioma, any site	0.003	0.997	0.000
H81.3 Other peripheral vertigo	0.000	0.997	0.003
E87.4 Mixed disorder of acid-base balance	0.003	0.997	0.000
K50.0 Crohn's disease of small intestine	0.000	0.997	0.003
L40.5 Arthropathic psoriasis	0.003	0.997	0.000
H81.8 Other disorders of vestibular function	0.000	0.997	0.003
E73.8 Other lactose intolerance	0.003	0.997	0.000
E73.1 Secondary lactase deficiency	0.003	0.997	0.000
E73.0 Congenital lactase deficiency	0.003	0.997	0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.003	0.997	0.000
A49.8 Other bacterial infections of unspecified site	0.003	0.997	0.000
R52.2 Other chronic pain	0.000	0.997	0.003
H81.9 Disorder of vestibular function, unspecified	0.000	0.997	0.003
H81.4 Vertigo of central origin	0.000	0.997	0.003
N48.6 Balanitis xerotica obliterans	0.003	0.997	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.003	0.997	0.000
E85.8 Other amyloidosis	0.002	0.997	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.002	0.997	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.002	0.997	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.002	0.997	0.000
N41.0 Acute prostatitis	0.000	0.997	0.003
F52 Sexual dysfunction, not caused by organic disorder or disease	0.003	0.997	0.000
Y81 General- and plastic-surgery devices associated with adverse incidents	0.003	0.997	0.000
Y71 Cardiovascular devices associated with adverse incidents	0.003	0.997	0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.003	0.997	0.000
E16 Other disorders of pancreatic internal secretion	0.003	0.997	0.000
M17.1 Other primary gonarthrosis	0.003	0.997	0.000
Y81.2 Prosthetic and other implants, materials and accessory devices	0.002	0.997	0.000
E85.9 Amyloidosis, unspecified	0.002	0.997	0.000
F52.0 Lack or loss of sexual desire	0.002	0.997	0.000
D36 Benign neoplasm of other and unspecified sites	0.000	0.997	0.002
E85.3 Secondary systemic amyloidosis	0.002	0.997	0.000
K76.8 Other specified diseases of liver	0.002	0.998	0.000
N48.4 Impotence of organic origin	0.002	0.998	0.000
M17 Gonarthrosis [arthrosis of knee]	0.002	0.998	0.000
S14.1 Other and unspecified injuries of cervical spinal cord	0.002	0.998	0.000
Q62.5 Duplication of ureter	0.002	0.998	0.000
L40.9 Psoriasis, unspecified	0.002	0.998	0.000
S64.4 Injury of digital nerve of other finger	0.000	0.998	0.002
Y71.2 Prosthetic and other implants, materials and accessory devices	0.002	0.998	0.000
S50.9 Superficial injury of forearm, unspecified	0.000	0.998	0.002
C81.9 Hodgkin's disease, unspecified	0.000	0.998	0.002
M17.3 Other posttraumatic gonarthrosis	0.002	0.998	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.002	0.998	0.000
S62.30 Fracture of other metacarpal bone (closed)	0.002	0.998	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.998	0.002
I77.6 Arteritis, unspecified	0.000	0.998	0.002
Y71.1 Therapeutic (nonsurgical) and rehabilitative devices	0.002	0.998	0.000
Y82 Other and unspecified medical devices associated with adverse incidents	0.002	0.998	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.998	0.002
D51 Vitamin B12 deficiency anaemia	0.000	0.998	0.002
Y80 Physical medicine devices associated with adverse incidents	0.002	0.998	0.000
Y78 Radiological devices associated with adverse incidents	0.002	0.998	0.000
Y75 Neurological devices associated with adverse incidents	0.002	0.998	0.000
Y74 General hospital and personal-use devices associated with adverse incidents	0.002	0.998	0.000
Y72 Otorhinolaryngological devices associated with adverse incidents	0.002	0.998	0.000
Y70 Anaesthesiology devices associated with adverse incidents	0.002	0.998	0.000
Y77 Ophthalmic devices associated with adverse incidents	0.002	0.998	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.002	0.998	0.000
F52.9 Unspecified sexual dysfunction, not caused by organic disorder or disease	0.002	0.998	0.000
F52.8 Other sexual dysfunction, not caused by organic disorder or disease	0.002	0.998	0.000
F52.7 Excessive sexual drive	0.002	0.998	0.000
F52.6 Nonorganic dyspareunia	0.002	0.998	0.000
F52.5 Nonorganic vaginismus	0.002	0.998	0.000
F52.4 Premature ejaculation	0.002	0.998	0.000
F52.3 Orgasmic dysfunction	0.002	0.998	0.000
F52.1 Sexual aversion and lack of sexual enjoyment	0.002	0.998	0.000
A49.1 Streptococcal infection, unspecified	0.002	0.998	0.000
M17.2 Posttraumatic gonarthrosis, bilateral	0.002	0.998	0.000
Q82.8 Other specified congenital malformations of skin	0.000	0.998	0.002
Y71.8 Miscellaneous devices, not elsewhere classified	0.002	0.998	0.000
Y71.3 Surgical instruments, materials and devices (including sutures)	0.002	0.998	0.000
Y71.0 Diagnostic and monitoring devices	0.002	0.998	0.000
Y81.8 Miscellaneous devices, not elsewhere classified	0.002	0.998	0.000
Y81.3 Surgical instruments, materials and devices (including sutures)	0.002	0.998	0.000
Y81.1 Therapeutic (nonsurgical) and rehabilitative devices	0.002	0.998	0.000
Y81.0 Diagnostic and monitoring devices	0.002	0.998	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.002	0.998	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.002	0.998	0.000
E16.4 Abnormal secretion of gastrin	0.002	0.998	0.000
E16.3 Increased secretion of glucagon	0.002	0.998	0.000
E73.9 Lactose intolerance, unspecified	0.002	0.998	0.000
H54.9 Unspecified visual impairment (binocular)	0.002	0.998	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.002	0.998	0.000
X23.9 Unspecified place	0.000	0.998	0.002
W06.0 Home	0.002	0.998	0.000
Y73 Gastro-enterology and urology devices associated with adverse incidents	0.002	0.998	0.000
D36.0 Lymph nodes	0.000	0.998	0.002
E16.1 Other hypoglycaemia	0.002	0.998	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.002	0.998	0.000
K09.0 Developmental odontogenic cysts	0.000	0.998	0.002
K76 Other diseases of liver	0.002	0.998	0.000
N30.9 Cystitis, unspecified	0.000	0.998	0.002
E85.4 Organ-limited amyloidosis	0.002	0.998	0.000
S13.1 Dislocation of cervical vertebra	0.002	0.998	0.000
C84.5 Other and unspecified T-cell lymphomas	0.000	0.998	0.002
F80.1 Expressive language disorder	0.002	0.998	0.000
K10.8 Other specified diseases of jaws	0.000	0.998	0.002
A49 Bacterial infection of unspecified site	0.002	0.998	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.000	0.998	0.002
C88.0 Waldenstrom's macroglobulinaemia	0.000	0.998	0.002
S22.20 Fracture of sternum (closed)	0.000	0.998	0.002
M17.5 Other secondary gonarthrosis	0.002	0.998	0.000
Y82.2 Prosthetic and other implants, materials and accessory devices	0.002	0.998	0.000
Y76 Obstetric and gynaecological devices associated with adverse incidents	0.002	0.998	0.000
H00.0 Hordeolum and other deep inflammation of eyelid	0.002	0.998	0.000
O82.1 Delivery by emergency Caesarean section	0.002	0.998	0.000
K76.7 Hepatorenal syndrome	0.002	0.998	0.000
Y82.8 Miscellaneous devices, not elsewhere classified	0.002	0.998	0.000
Y82.3 Surgical instruments, materials and devices (including sutures)	0.002	0.998	0.000
Y82.1 Therapeutic (nonsurgical) and rehabilitative devices	0.002	0.998	0.000
Y82.0 Diagnostic and monitoring devices	0.002	0.998	0.000
C84.4 Peripheral T-cell lymphoma	0.000	0.998	0.002
D36.9 Benign neoplasm of unspecified site	0.000	0.998	0.002
D51.8 Other vitamin B12 deficiency anaemias	0.000	0.998	0.002
D51.2 Transcobalamin II deficiency	0.000	0.998	0.002
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.000	0.998	0.002
Y70.8 Miscellaneous devices, not elsewhere classified	0.002	0.998	0.000
Y70.3 Surgical instruments, materials and devices (including sutures)	0.002	0.998	0.000
Y70.2 Prosthetic and other implants, materials and accessory devices	0.002	0.998	0.000
Y70.1 Therapeutic (nonsurgical) and rehabilitative devices	0.002	0.998	0.000
Y70.0 Diagnostic and monitoring devices	0.002	0.998	0.000
Y72.8 Miscellaneous devices, not elsewhere classified	0.002	0.998	0.000
Y72.3 Surgical instruments, materials and devices (including sutures)	0.002	0.998	0.000
Y72.2 Prosthetic and other implants, materials and accessory devices	0.002	0.998	0.000
Y72.1 Therapeutic (nonsurgical) and rehabilitative devices	0.002	0.998	0.000
Y72.0 Diagnostic and monitoring devices	0.002	0.998	0.000
Y74.8 Miscellaneous devices, not elsewhere classified	0.002	0.998	0.000
Y74.3 Surgical instruments, materials and devices (including sutures)	0.002	0.998	0.000
Y74.2 Prosthetic and other implants, materials and accessory devices	0.002	0.998	0.000
Y74.1 Therapeutic (nonsurgical) and rehabilitative devices	0.002	0.998	0.000
Y74.0 Diagnostic and monitoring devices	0.002	0.998	0.000
Y75.8 Miscellaneous devices, not elsewhere classified	0.002	0.998	0.000
Y75.3 Surgical instruments, materials and devices (including sutures)	0.002	0.998	0.000
Y75.2 Prosthetic and other implants, materials and accessory devices	0.002	0.998	0.000
Y75.1 Therapeutic (nonsurgical) and rehabilitative devices	0.002	0.998	0.000
Y75.0 Diagnostic and monitoring devices	0.002	0.998	0.000
Y78.8 Miscellaneous devices, not elsewhere classified	0.002	0.998	0.000
Y78.3 Surgical instruments, materials and devices (including sutures)	0.002	0.998	0.000
Y78.2 Prosthetic and other implants, materials and accessory devices	0.002	0.998	0.000
Y78.1 Therapeutic (nonsurgical) and rehabilitative devices	0.002	0.998	0.000
Y78.0 Diagnostic and monitoring devices	0.002	0.998	0.000
Y80.8 Miscellaneous devices, not elsewhere classified	0.002	0.998	0.000
Y80.3 Surgical instruments, materials and devices (including sutures)	0.002	0.998	0.000
Y80.2 Prosthetic and other implants, materials and accessory devices	0.002	0.998	0.000
Y80.1 Therapeutic (nonsurgical) and rehabilitative devices	0.002	0.998	0.000
Y80.0 Diagnostic and monitoring devices	0.002	0.998	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.000	0.998	0.002
O36.6 Maternal care for excessive foetal growth	0.002	0.998	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.000	0.998	0.002
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.002	0.998	0.000
E89.5 Postprocedural testicular hypofunction	0.002	0.998	0.000
E89.1 Postprocedural hypoinsulinaemia	0.002	0.998	0.000
Y77.8 Miscellaneous devices, not elsewhere classified	0.002	0.998	0.000
Y77.2 Prosthetic and other implants, materials and accessory devices	0.002	0.998	0.000
Y77.1 Therapeutic (nonsurgical) and rehabilitative devices	0.002	0.998	0.000
Y77.0 Diagnostic and monitoring devices	0.002	0.998	0.000
Z30.5 Surveillance of (intra-uterine) contraceptive device	0.002	0.998	0.000
E87.3 Alkalosis	0.002	0.998	0.000
U80.8 Agent resistant to other penicillin-related antibiotic	0.002	0.998	0.000
M17.4 Other secondary gonarthrosis, bilateral	0.002	0.998	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.002	0.998	0.000
S13.0 Traumatic rupture of cervical intervertebral disk	0.002	0.998	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.002	0.998	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.000	0.998	0.002
E78.4 Other hyperlipidaemia	0.002	0.998	0.000
Y77.3 Surgical instruments, materials and devices (including sutures)	0.002	0.998	0.000
C81 Hodgkin's disease	0.000	0.998	0.002
C84.0 Mycosis fungoides	0.000	0.998	0.002
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.000	0.998	0.002
K10.0 Developmental disorders of jaws	0.000	0.998	0.002
S39.8 Other specified injuries of abdomen, lower back and pelvis	0.002	0.998	0.000
K76.5 Hepatic veno-occlusive disease	0.002	0.998	0.000
K76.4 Peliosis hepatis	0.002	0.998	0.000
K76.3 Infarction of liver	0.002	0.998	0.000
K76.2 Central haemorrhagic necrosis of liver	0.002	0.998	0.000
K76.1 Chronic passive congestion of liver	0.002	0.998	0.000
L57.0 Actinic keratosis	0.000	0.998	0.002
Y73.8 Miscellaneous devices, not elsewhere classified	0.001	0.998	0.000
Y73.3 Surgical instruments, materials and devices (including sutures)	0.001	0.998	0.000
Y73.1 Therapeutic (nonsurgical) and rehabilitative devices	0.001	0.998	0.000
Y73.0 Diagnostic and monitoring devices	0.001	0.998	0.000
D36.7 Other specified sites	0.000	0.998	0.002
S13.4 Sprain and strain of cervical spine	0.002	0.998	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.002	0.998	0.000
S14 Injury of nerves and spinal cord at neck level	0.002	0.998	0.000
K10.2 Inflammatory conditions of jaws	0.000	0.998	0.002
A49.3 Mycoplasma infection, unspecified	0.002	0.998	0.000
E89.4 Postprocedural ovarian failure	0.002	0.998	0.000
Z96.8 Presence of other specified functional implants	0.002	0.998	0.000
A49.2 Haemophilus influenzae infection, unspecified	0.002	0.998	0.000
Y76.8 Miscellaneous devices, not elsewhere classified	0.001	0.998	0.000
Y76.3 Surgical instruments, materials and devices (including sutures)	0.001	0.998	0.000
Y76.1 Therapeutic (nonsurgical) and rehabilitative devices	0.001	0.998	0.000
Y76.0 Diagnostic and monitoring devices	0.001	0.998	0.000
N15.9 Renal tubulo-interstitial disease, unspecified	0.000	0.998	0.002
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.002	0.998	0.000
C84.9 Mature T/NK-cell lymphoma, unspecified	0.000	0.998	0.001
C84.8 Cutaneous T-cell lymphoma, unspecified	0.000	0.998	0.001
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.000	0.998	0.001
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.000	0.998	0.001
C84.3 Lymphoepithelioid lymphoma	0.000	0.998	0.001
C84.2 T-zone lymphoma	0.000	0.998	0.001
C84.1 Sezary's diease	0.000	0.998	0.001
K10 Other diseases of jaws	0.000	0.998	0.002
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.998	0.002
Y53 Agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
B19.9 Unspecified viral hepatitis without coma	0.002	0.998	0.000
D18 Haemangioma and lymphangioma, any site	0.002	0.998	0.000
A49.0 Staphylococcal infection, unspecified	0.002	0.998	0.000
C81.2 Mixed cellularity	0.000	0.998	0.001
K10.3 Alveolitis of jaws	0.000	0.998	0.002
Q62.2 Congenital megaloureter	0.001	0.998	0.000
D21.0 Connective and other soft tissue of head, face and neck	0.002	0.998	0.000
E89.2 Postprocedural hypoparathyroidism	0.001	0.998	0.000
S13.5 Sprain and strain of thyroid region	0.001	0.998	0.000
S13.3 Multiple dislocations of neck	0.001	0.998	0.000
S13.2 Dislocation of other and unspecified parts of neck	0.001	0.998	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.001	0.998	0.000
C34.3 Lower lobe, bronchus or lung	0.000	0.998	0.002
C81.7 Other Hodgkin's disease	0.000	0.998	0.001
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.000	0.998	0.001
C81.3 Lymphocytic depletion	0.000	0.998	0.001
D89.1 Cryoglobulinaemia	0.000	0.998	0.001
Z12.5 Special screening examination for neoplasm of prostate	0.002	0.998	0.000
C88 Malignant immunoproliferative diseases	0.000	0.998	0.001
Y73.2 Prosthetic and other implants, materials and accessory devices	0.001	0.998	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.000	0.998	0.001
C82.0 Small cleaved cell, follicular	0.000	0.998	0.001
C92.1 Chronic myeloid leukaemia	0.000	0.998	0.001
Q62.8 Other congenital malformations of ureter	0.001	0.998	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.001	0.998	0.000
Q62.6 Malposition of ureter	0.001	0.998	0.000
Q62.4 Agenesis of ureter	0.001	0.998	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.001	0.998	0.000
Q62.1 Atresia and stenosis of ureter	0.001	0.998	0.000
Q62.0 Congenital hydronephrosis	0.001	0.998	0.000
S14.6 Injury of other and unspecified nerves of neck	0.001	0.998	0.000
S14.5 Injury of cervical sympathetic nerves	0.001	0.998	0.000
S14.4 Injury of peripheral nerves of neck	0.001	0.998	0.000
S14.2 Injury of nerve root of cervical spine	0.001	0.998	0.000
S14.0 Concussion and oedema of cervical spinal cord	0.001	0.998	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.000	0.998	0.002
C81.1 Nodular sclerosis	0.000	0.998	0.001
C81.0 Lymphocytic predominance	0.000	0.998	0.001
D89.0 Polyclonal hypergammaglobulinaemia	0.000	0.999	0.001
N15.1 Renal and perinephric abscess	0.000	0.999	0.001
S13.6 Sprain and strain of joints and ligaments of other and unspecified parts of neck	0.001	0.999	0.000
Z56.6 Other physical and mental strain related to work	0.001	0.999	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.001	0.999	0.000
C82.2 Large cell, follicular	0.000	0.999	0.001
D18.1 Lymphangioma, any site	0.001	0.999	0.000
R94.3 Abnormal results of cardiovascular function studies	0.000	0.999	0.001
M25.06 Haemarthrosis (Lower leg)	0.001	0.999	0.000
M79.00 Rheumatism, unspecified (Multiple sites)	0.000	0.999	0.001
D89.3 Immune reconstitution syndrome	0.000	0.999	0.001
K10.1 Giant cell granuloma, central	0.000	0.999	0.001
M96.9 Postprocedural musculoskeletal disorder, unspecified	0.000	0.999	0.001
S14.3 Injury of brachial plexus	0.001	0.999	0.000
S39.7 Other multiple injuries of abdomen, lower back and pelvis	0.001	0.999	0.000
S39.6 Injury of intra-abdominal organ(s) with pelvic organ(s)	0.001	0.999	0.000
Z01.9 Special examination, unspecified	0.001	0.999	0.000
M54.89 Other dorsalgia (Site unspecified)	0.000	0.999	0.001
E89.3 Postprocedural hypopituitarism	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations