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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs6798318
log Bayes Factor = 15.5218
Chromosome 3   position 81,391,273  (GRCh37) Explore rs6798318 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
N30-N39 Other diseases of urinary system
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
N32 Other disorders of bladder
0.999 0.001 0.000
E10-E14 Diabetes mellitus
0.999 0.001 0.000
Chapter VI Diseases of the nervous system
0.996 0.004 0.000
Chapter V Mental and behavioural disorders
0.996 0.004 0.000
N32.8 Other specified disorders of bladder
0.994 0.006 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.994 0.006 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.994 0.006 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.988 0.012 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.988 0.012 0.000
G90-G99 Other disorders of the nervous system
0.985 0.015 0.000
I10-I15 Hypertensive diseases
0.982 0.018 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.975 0.025 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.973 0.027 0.000
Chapter I Certain infectious and parasitic diseases
0.971 0.029 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.967 0.033 0.000
E11 Non-insulin-dependent diabetes mellitus
0.965 0.035 0.000
E10 Insulin-dependent diabetes mellitus
0.952 0.048 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.952 0.048 0.000
E14 Unspecified diabetes mellitus
0.951 0.049 0.000
M45-M49 Spondylopathies
0.949 0.051 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.949 0.051 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.948 0.052 0.000
E65-E68 Obesity and other hyperalimentation
0.946 0.054 0.000
Chapter VII Diseases of the eye and adnexa
0.943 0.057 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.941 0.059 0.000
I10 Essential (primary) hypertension
0.938 0.062 0.000
H30-H36 Disorders of choroid and retina
0.937 0.063 0.000
G93 Other disorders of brain
0.937 0.063 0.000
F30-F39 Mood [affective] disorders
0.936 0.064 0.000
N32.3 Diverticulum of bladder
0.931 0.069 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.929 0.071 0.000
N80 Endometriosis
0.928 0.072 0.000
R41.0 Disorientation, unspecified
0.927 0.073 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.917 0.083 0.000
H35 Other retinal disorders
0.914 0.086 0.000
F33 Recurrent depressive disorder
0.912 0.088 0.000
E20-E35 Disorders of other endocrine glands
0.912 0.088 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.908 0.092 0.000
E66 Obesity
0.907 0.093 0.000
M47 Spondylosis
0.906 0.094 0.000
I12 Hypertensive renal disease
0.904 0.096 0.000
N92 Excessive, frequent and irregular menstruation
0.899 0.101 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.899 0.101 0.000
R42 Dizziness and giddiness
0.898 0.102 0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.898 0.102 0.000
E66.9 Obesity, unspecified
0.894 0.106 0.000
B25-B34 Other viral diseases
0.892 0.108 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.890 0.110 0.000
E10.9 Without complications
0.889 0.111 0.000
H36 Retinal disorders in diseases classified elsewhere
0.887 0.113 0.000
I77 Other disorders of arteries and arterioles
0.886 0.114 0.000
M47.9 Spondylosis, unspecified
0.886 0.114 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.884 0.116 0.000
E14.9 Without complications
0.882 0.118 0.000
E11.3 With ophthalmic complications
0.878 0.122 0.000
M65-M68 Disorders of synovium and tendon
0.876 0.124 0.000
Chapter VIII Diseases of the ear and mastoid process
0.875 0.125 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.873 0.127 0.000
M05-M14 Inflammatory polyarthropathies
0.870 0.130 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.870 0.130 0.000
N36 Other disorders of urethra
0.869 0.131 0.000
I20-I25 Ischaemic heart diseases
0.869 0.131 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.868 0.132 0.000
N80.0 Endometriosis of uterus
0.868 0.132 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.865 0.135 0.000
F99-F99 Unspecified mental disorder
0.864 0.136 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.863 0.137 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.863 0.137 0.000
G30-G32 Other degenerative diseases of the nervous system
0.858 0.142 0.000
N94.1 Dyspareunia
0.857 0.143 0.000
R74 Abnormal serum enzyme levels
0.857 0.143 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.856 0.144 0.000
I89.0 Lymphoedema, not elsewhere classified
0.855 0.145 0.000
H35.8 Other specified retinal disorders
0.854 0.146 0.000
N31.8 Other neuromuscular dysfunction of bladder
0.854 0.146 0.000
H36.0 Diabetic retinopathy
0.851 0.149 0.000
N83.0 Follicular cyst of ovary
0.851 0.149 0.000
N92.0 Excessive and frequent menstruation with regular cycle
0.848 0.152 0.000
N87 Dysplasia of cervix uteri
0.848 0.152 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.846 0.154 0.000
I21 Acute myocardial infarction
0.843 0.157 0.000
N94.6 Dysmenorrhoea, unspecified
0.841 0.159 0.000
M13 Other arthritis
0.840 0.160 0.000
H35.3 Degeneration of macula and posterior pole
0.840 0.160 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.839 0.161 0.000
M70-M79 Other soft tissue disorders
0.839 0.161 0.000
R25 Abnormal involuntary movements
0.838 0.162 0.000
M86-M90 Other osteopathies
0.835 0.165 0.000
B34 Viral infection of unspecified site
0.835 0.165 0.000
B95-B98 Bacterial, viral and other infectious agents
0.831 0.169 0.000
E11.6 With other specified complications
0.827 0.173 0.000
I81 Portal vein thrombosis
0.825 0.175 0.000
N32.0 Bladder-neck obstruction
0.822 0.178 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.821 0.179 0.000
M13.9 Arthritis, unspecified
0.818 0.182 0.000
Chapter XXII Codes for special purposes
0.818 0.182 0.000
E14.3 With ophthalmic complications
0.817 0.183 0.000
N73 Other female pelvic inflammatory diseases
0.813 0.187 0.000
I82 Other venous embolism and thrombosis
0.813 0.187 0.000
E10.3 With ophthalmic complications
0.812 0.188 0.000
F60-F69 Disorders of adult personality and behaviour
0.811 0.189 0.000
R73 Elevated blood glucose level
0.810 0.190 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.809 0.191 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.809 0.191 0.000
I77.1 Stricture of artery
0.809 0.191 0.000
I74 Arterial embolism and thrombosis
0.808 0.192 0.000
N36.2 Urethral caruncle
0.806 0.194 0.000
R41.3 Other amnesia
0.804 0.196 0.000
E16 Other disorders of pancreatic internal secretion
0.801 0.199 0.000
E23 Hypofunction and other disorders of pituitary gland
0.801 0.199 0.000
R45 Symptoms and signs involving emotional state
0.800 0.200 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.800 0.200 0.000
M65 Synovitis and tenosynovitis
0.800 0.200 0.000
N60-N64 Disorders of breast
0.800 0.200 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.799 0.201 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.797 0.203 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.797 0.203 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.795 0.205 0.000
I12.0 Hypertensive renal disease with renal failure
0.795 0.205 0.000
B34.9 Viral infection, unspecified
0.794 0.206 0.000
N89 Other noninflammatory disorders of vagina
0.791 0.209 0.000
R74.8 Abnormal levels of other serum enzymes
0.791 0.209 0.000
G91 Hydrocephalus
0.790 0.210 0.000
N94.3 Premenstrual tension syndrome
0.785 0.215 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.785 0.215 0.000
R26 Abnormalities of gait and mobility
0.783 0.217 0.000
S40-S49 Injuries to the shoulder and upper arm
0.782 0.218 0.000
G40-G47 Episodic and paroxysmal disorders
0.781 0.219 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.779 0.221 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.779 0.221 0.000
F80-F89 Disorders of psychological development
0.779 0.221 0.000
M45 Ankylosing spondylitis
0.779 0.221 0.000
G93.9 Disorder of brain, unspecified
0.778 0.222 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.775 0.224 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.775 0.225 0.000
I12.9 Hypertensive renal disease without renal failure
0.774 0.225 0.000
I86 Varicose veins of other sites
0.774 0.226 0.000
G90 Disorders of autonomic nervous system
0.771 0.229 0.000
H53-H54 Visual disturbances and blindness
0.771 0.229 0.000
I95 Hypotension
0.770 0.230 0.000
F99 Mental disorder, not otherwise specified
0.770 0.230 0.000
G96 Other disorders of central nervous system
0.769 0.231 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.768 0.232 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.767 0.233 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.767 0.233 0.000
E10.2 With renal complications
0.766 0.234 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.763 0.237 0.000
S90-S99 Injuries to the ankle and foot
0.763 0.237 0.000
E11.9 Without complications
0.763 0.237 0.000
N80.3 Endometriosis of pelvic peritoneum
0.763 0.237 0.000
N30 Cystitis
0.761 0.239 0.000
G20-G26 Extrapyramidal and movement disorders
0.760 0.240 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.760 0.240 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.759 0.241 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.759 0.241 0.000
N83.1 Corpus luteum cyst
0.758 0.242 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.758 0.242 0.000
F33.9 Recurrent depressive disorder, unspecified
0.756 0.244 0.000
I24 Other acute ischaemic heart diseases
0.755 0.245 0.000
N73.6 Female pelvic peritoneal adhesions
0.753 0.247 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.752 0.248 0.000
G93.3 Postviral fatigue syndrome
0.751 0.249 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.749 0.251 0.000
G70-G73 Diseases of myoneural junction and muscle
0.749 0.251 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.748 0.252 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.748 0.252 0.000
T66-T78 Other and unspecified effects of external causes
0.747 0.253 0.000
I21.4 Acute subendocardial myocardial infarction
0.747 0.253 0.000
B15-B19 Viral hepatitis
0.744 0.256 0.000
N76 Other inflammation of vagina and vulva
0.743 0.257 0.000
B07 Viral warts
0.742 0.258 0.000
H34 Retinal vascular occlusions
0.742 0.258 0.000
E70-E90 Metabolic disorders
0.742 0.258 0.000
E16.2 Hypoglycaemia, unspecified
0.741 0.259 0.000
I95.9 Hypotension, unspecified
0.740 0.260 0.000
N34 Urethritis and urethral syndrome
0.739 0.260 0.000
N32.9 Bladder disorder, unspecified
0.739 0.261 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.739 0.261 0.000
M40-M43 Deforming dorsopathies
0.739 0.261 0.000
S50-S59 Injuries to the elbow and forearm
0.738 0.262 0.000
G93.2 Benign intracranial hypertension
0.737 0.263 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.737 0.263 0.000
N35 Urethral stricture
0.736 0.264 0.000
N88 Other noninflammatory disorders of cervix uteri
0.735 0.265 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.735 0.265 0.000
T79-T79 Certain early complications of trauma
0.735 0.265 0.000
M91-M94 Chondropathies
0.734 0.266 0.000
G93.0 Cerebral cysts
0.733 0.267 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.731 0.269 0.000
T51 Toxic effect of alcohol
0.731 0.269 0.000
S70-S79 Injuries to the hip and thigh
0.730 0.269 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.730 0.270 0.000
I60-I69 Cerebrovascular diseases
0.729 0.271 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.729 0.271 0.000
N80.1 Endometriosis of ovary
0.729 0.271 0.000
I87 Other disorders of veins
0.727 0.273 0.000
E11.2 With renal complications
0.727 0.273 0.000
N17-N19 Renal failure
0.727 0.273 0.000
E26 Hyperaldosteronism
0.727 0.273 0.000
E11.4 With neurological complications
0.726 0.274 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.725 0.275 0.000
M80-M85 Disorders of bone density and structure
0.724 0.276 0.000
N70 Salpingitis and oophoritis
0.722 0.278 0.000
H31 Other disorders of choroid
0.722 0.278 0.000
N83.2 Other and unspecified ovarian cysts
0.721 0.279 0.000
E23.0 Hypopituitarism
0.721 0.279 0.000
G47 Sleep disorders
0.720 0.280 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
N37 Urethral disorders in diseases classified elsewhere
0.717 0.283 0.000
N33 Bladder disorders in diseases classified elsewhere
0.717 0.283 0.000
R94 Abnormal results of function studies
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
N32.4 Rupture of bladder, nontraumatic
0.716 0.284 0.000
N32.2 Vesical fistula, not elsewhere classified
0.716 0.284 0.000
E13 Other specified diabetes mellitus
0.716 0.284 0.000
E12 Malnutrition-related diabetes mellitus
0.716 0.284 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.715 0.285 0.000
T58 Toxic effect of carbon monoxide
0.715 0.285 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.714 0.286 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.714 0.286 0.000
F70-F79 Mental retardation
0.714 0.286 0.000
N98 Complications associated with artificial fertilisation
0.713 0.287 0.000
N91 Absent, scanty and rare menstruation
0.713 0.287 0.000
N82 Fistulae involving female genital tract
0.713 0.287 0.000
N96 Habitual aborter
0.713 0.287 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.713 0.287 0.000
H80-H83 Diseases of inner ear
0.712 0.288 0.000
N92.5 Other specified irregular menstruation
0.710 0.290 0.000
E40-E46 Malnutrition
0.710 0.290 0.000
M89 Other disorders of bone
0.710 0.290 0.000
S20-S29 Injuries to the thorax
0.709 0.291 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.709 0.291 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.709 0.291 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.708 0.292 0.000
R46 Symptoms and signs involving appearance and behaviour
0.708 0.292 0.000
R43 Disturbances of smell and taste
0.708 0.292 0.000
M60-M63 Disorders of muscles
0.708 0.292 0.000
M00-M03 Infectious arthropathies
0.708 0.292 0.000
Chapter XX External causes of morbidity and mortality
0.708 0.292 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.707 0.293 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.706 0.294 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.706 0.294 0.000
G92 Toxic encephalopathy
0.706 0.294 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.706 0.294 0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified
0.706 0.294 0.000
R25.3 Fasciculation
0.705 0.295 0.000
I15 Secondary hypertension
0.704 0.296 0.000
I13 Hypertensive heart and renal disease
0.704 0.296 0.000
I11 Hypertensive heart disease
0.704 0.296 0.000
E11.5 With peripheral circulatory complications
0.704 0.296 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.703 0.297 0.000
N87.9 Dysplasia of cervix uteri, unspecified
0.702 0.298 0.000
F03 Unspecified dementia
0.702 0.298 0.000
A00-A09 Intestinal infectious diseases
0.701 0.299 0.000
F00 Dementia in Alzheimer's disease
0.700 0.300 0.000
N00-N08 Glomerular diseases
0.699 0.301 0.000
T33-T35 Frostbite
0.699 0.301 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.699 0.301 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.699 0.301 0.000
T00-T07 Injuries involving multiple body regions
0.699 0.301 0.000
S10-S19 Injuries to the neck
0.699 0.301 0.000
N25-N29 Other disorders of kidney and ureter
0.699 0.301 0.000
H43-H45 Disorders of vitreous body and globe
0.698 0.302 0.000
R41.2 Retrograde amnesia
0.698 0.302 0.000
R41.1 Anterograde amnesia
0.698 0.302 0.000
H65-H75 Diseases of middle ear and mastoid
0.697 0.303 0.000
H55-H59 Other disorders of eye and adnexa
0.697 0.303 0.000
B99-B99 Other infectious diseases
0.696 0.304 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.696 0.304 0.000
B65-B83 Helminthiases
0.696 0.304 0.000
B50-B64 Protozoal diseases
0.696 0.304 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.696 0.304 0.000
A75-A79 Rickettsioses
0.696 0.304 0.000
A70-A74 Other diseases caused by chlamydiae
0.696 0.304 0.000
A65-A69 Other spirochaetal diseases
0.696 0.304 0.000
A20-A28 Certain zoonotic bacterial diseases
0.696 0.304 0.000
A15-A19 Tuberculosis
0.696 0.304 0.000
N32.1 Vesicointestinal fistula
0.696 0.304 0.000
N62 Hypertrophy of breast
0.696 0.304 0.000
E28 Ovarian dysfunction
0.695 0.305 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.695 0.305 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.695 0.305 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.695 0.305 0.000
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified
0.693 0.307 0.000
N83.7 Haematoma of broad ligament
0.693 0.307 0.000
N83.6 Haematosalpinx
0.693 0.307 0.000
N83.5 Torsion of ovary, ovarian pedicle and Fallopian tube
0.693 0.307 0.000
N83.4 Prolapse and hernia of ovary and Fallopian tube
0.693 0.307 0.000
N83.3 Acquired atrophy of ovary and Fallopian tube
0.693 0.307 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.693 0.307 0.000
I89.1 Lymphangitis
0.692 0.307 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.692 0.308 0.000
I82.8 Embolism and thrombosis of other specified veins
0.692 0.308 0.000
M47.2 Other spondylosis with radiculopathy
0.692 0.308 0.000
E11.8 With unspecified complications
0.692 0.308 0.000
E11.7 With multiple complications
0.692 0.308 0.000
E11.1 With ketoacidosis
0.692 0.308 0.000
E11.0 With coma
0.692 0.308 0.000
A80-A89 Viral infections of the central nervous system
0.692 0.308 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.692 0.308 0.000
Q80-Q89 Other congenital malformations
0.691 0.309 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.691 0.309 0.000
M77 Other enthesopathies
0.691 0.309 0.000
G93.8 Other specified disorders of brain
0.691 0.309 0.000
N99-N99 Other disorders of the genitourinary system
0.690 0.310 0.000
I70 Atherosclerosis
0.687 0.313 0.000
M46 Other inflammatory spondylopathies
0.687 0.313 0.000
H10-H13 Disorders of conjunctiva
0.686 0.314 0.000
H35.4 Peripheral retinal degeneration
0.686 0.314 0.000
G47.3 Sleep apnoea
0.685 0.315 0.000
N87.0 Mild cervical dysplasia
0.685 0.315 0.000
H35.7 Separation of retinal layers
0.685 0.315 0.000
N87.2 Severe cervical dysplasia, not elsewhere classified
0.684 0.315 0.000
M13.98 Arthritis, unspecified (Other)
0.684 0.316 0.000
R45.1 Restlessness and agitation
0.684 0.316 0.000
N30.2 Other chronic cystitis
0.684 0.316 0.000
F10.1 Harmful use
0.683 0.317 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.683 0.317 0.000
M13.93 Arthritis, unspecified (Forearm)
0.683 0.317 0.000
E10.8 With unspecified complications
0.682 0.317 0.000
E10.7 With multiple complications
0.682 0.317 0.000
E10.6 With other specified complications
0.682 0.317 0.000
E10.5 With peripheral circulatory complications
0.682 0.317 0.000
E10.4 With neurological complications
0.682 0.317 0.000
E10.0 With coma
0.682 0.317 0.000
N94.5 Secondary dysmenorrhoea
0.682 0.317 0.000
N94.4 Primary dysmenorrhoea
0.682 0.317 0.000
N94.2 Vaginismus
0.682 0.317 0.000
N94.0 Mittelschmerz
0.682 0.317 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.682 0.318 0.000
E14.8 With unspecified complications
0.682 0.318 0.000
E14.7 With multiple complications
0.682 0.318 0.000
E14.6 With other specified complications
0.682 0.318 0.000
E14.5 With peripheral circulatory complications
0.682 0.318 0.000
E14.4 With neurological complications
0.682 0.318 0.000
E14.2 Withrenal complications
0.682 0.318 0.000
E14.1 With ketoacidosis
0.682 0.318 0.000
E14.0 With coma
0.682 0.318 0.000
F10.3 Withdrawal state
0.682 0.318 0.000
H35.9 Retinal disorder, unspecified
0.681 0.319 0.000
M49 Spondylopathies in diseases classified elsewhere
0.680 0.320 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.680 0.320 0.000
R77 Other abnormalities of plasma proteins
0.680 0.320 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.680 0.320 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.680 0.320 0.000
R71 Abnormality of red blood cells
0.680 0.320 0.000
I88 Nonspecific lymphadenitis
0.680 0.320 0.000
I71 Aortic aneurysm and dissection
0.679 0.320 0.000
G35 Multiple sclerosis
0.679 0.321 0.000
R47-R49 Symptoms and signs involving speech and voice
0.679 0.321 0.000
G93.6 Cerebral oedema
0.678 0.322 0.000
F60 Specific personality disorders
0.678 0.322 0.000
E67 Other hyperalimentation
0.678 0.322 0.000
E68 Sequelae of hyperalimentation
0.678 0.322 0.000
E65 Localised adiposity
0.678 0.322 0.000
O60-O75 Complications of labour and delivery
0.678 0.322 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.678 0.322 0.000
B35-B49 Mycoses
0.678 0.322 0.000
E22 Hyperfunction of pituitary gland
0.678 0.322 0.000
R25.1 Tremor, unspecified
0.676 0.324 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.675 0.325 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.675 0.325 0.000
I72 Other aneurysm
0.675 0.325 0.000
N80.8 Other endometriosis
0.673 0.326 0.000
I67 Other cerebrovascular diseases
0.673 0.327 0.000
N95 Menopausal and other perimenopausal disorders
0.673 0.327 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.673 0.327 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.673 0.327 0.000
H53 Visual disturbances
0.672 0.328 0.000
R73.9 Hyperglycaemia, unspecified
0.672 0.328 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.672 0.328 0.000
H30 Chorioretinal inflammation
0.672 0.328 0.000
G93.7 Reye's syndrome
0.672 0.328 0.000
G93.5 Compression of brain
0.672 0.328 0.000
G93.4 Encephalopathy, unspecified
0.672 0.328 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.672 0.328 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.672 0.328 0.000
F38 Other mood [affective] disorders
0.671 0.329 0.000
F34 Persistent mood [affective] disorders
0.671 0.329 0.000
F30 Manic episode
0.671 0.329 0.000
F39 Unspecified mood [affective] disorder
0.671 0.329 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.671 0.329 0.000
I85 Oesophageal varices
0.669 0.330 0.000
M48 Other spondylopathies
0.669 0.331 0.000
N72 Inflammatory disease of cervix uteri
0.668 0.332 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.666 0.334 0.000
N80.6 Endometriosis in cutaneous scar
0.666 0.334 0.000
N80.5 Endometriosis of intestine
0.666 0.334 0.000
N80.4 Endometriosis of rectovaginal septum and vagina
0.666 0.334 0.000
N80.2 Endometriosis of Fallopian tube
0.666 0.334 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.664 0.336 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.663 0.337 0.000
R94.5 Abnormal results of liver function studies
0.662 0.338 0.000
I78 Diseases of capillaries
0.661 0.339 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.660 0.339 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.660 0.340 0.000
R05 Cough
0.660 0.340 0.000
H60-H62 Diseases of external ear
0.659 0.340 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.659 0.341 0.000
N19 Unspecified renal failure
0.659 0.341 0.000
H90-H95 Other disorders of ear
0.658 0.342 0.000
T85.2 Mechanical complication of intraocular lens
0.658 0.342 0.000
N31.1 Reflex neuropathic bladder, not elsewhere classified
0.658 0.342 0.000
N31.0 Uninhibited neuropathic bladder, not elsewhere classified
0.658 0.342 0.000
M47.1 Other spondylosis with myelopathy
0.657 0.343 0.000
E27 Other disorders of adrenal gland
0.656 0.344 0.000
N89.8 Other specified noninflammatory disorders of vagina
0.656 0.344 0.000
H35.6 Retinal haemorrhage
0.655 0.345 0.000
H35.5 Hereditary retinal dystrophy
0.655 0.345 0.000
H35.2 Other proliferative retinopathy
0.655 0.345 0.000
H35.1 Retinopathy of prematurity
0.655 0.345 0.000
R76 Other abnormal immunological findings in serum
0.655 0.345 0.000
E88 Other metabolic disorders
0.655 0.345 0.000
T82.1 Mechanical complication of cardiac electronic device
0.655 0.345 0.000
N94.9 Unspecified condition associated with female genital organs and menstrual cycle
0.654 0.346 0.000
F33.8 Other recurrent depressive disorders
0.654 0.346 0.000
F33.4 Recurrent depressive disorder, currently in remission
0.654 0.346 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.654 0.346 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.654 0.346 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.654 0.346 0.000
E34 Other endocrine disorders
0.654 0.346 0.000
E32 Diseases of thymus
0.654 0.346 0.000
E31 Polyglandular dysfunction
0.654 0.346 0.000
E30 Disorders of puberty, not elsewhere classified
0.654 0.346 0.000
E25 Adrenogenital disorders
0.654 0.346 0.000
E24 Cushing's syndrome
0.654 0.346 0.000
E20 Hypoparathyroidism
0.654 0.346 0.000
I24.8 Other forms of acute ischaemic heart disease
0.653 0.347 0.000
N92.3 Ovulation bleeding
0.653 0.347 0.000
E29 Testicular dysfunction
0.653 0.347 0.000
Q00-Q07 Congenital malformations of the nervous system
0.652 0.347 0.000
F29 Unspecified nonorganic psychosis
0.652 0.348 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.651 0.349 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.650 0.349 0.000
E66.1 Drug-induced obesity
0.650 0.349 0.000
E66.0 Obesity due to excess calories
0.650 0.349 0.000
R79 Other abnormal findings of blood chemistry
0.650 0.350 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.650 0.350 0.000
G91.9 Hydrocephalus, unspecified
0.650 0.350 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.650 0.350 0.000
I86.1 Scrotal varices
0.649 0.351 0.000
G95 Other diseases of spinal cord
0.648 0.351 0.000
S60-S69 Injuries to the wrist and hand
0.648 0.352 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.648 0.352 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.647 0.353 0.000
R25.2 Cramp and spasm
0.647 0.353 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.646 0.353 0.000
N76.0 Acute vaginitis
0.646 0.354 0.000
I74.5 Embolism and thrombosis of iliac artery
0.646 0.354 0.000
N94.8 Other specified conditions associated with female genital organs and menstrual cycle
0.645 0.355 0.000
N71 Inflammatory disease of uterus, except cervix
0.645 0.355 0.000
N92.2 Excessive menstruation at puberty
0.645 0.355 0.000
Q50-Q56 Congenital malformations of genital organs
0.645 0.355 0.000
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.644 0.356 0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.644 0.356 0.000
R73.0 Abnormal glucose tolerance test
0.644 0.356 0.000
N10-N16 Renal tubulo-interstitial diseases
0.642 0.358 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.640 0.360 0.000
B33 Other viral diseases, not elsewhere classified
0.639 0.361 0.000
B30 Viral conjunctivitis
0.639 0.361 0.000
B27 Infectious mononucleosis
0.639 0.361 0.000
B26 Mumps
0.639 0.361 0.000
B25 Cytomegaloviral disease
0.639 0.361 0.000
B02 Zoster [herpes zoster]
0.638 0.362 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.638 0.362 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.638 0.362 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.638 0.362 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.638 0.362 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.638 0.362 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.638 0.362 0.000
F11 Mental and behavioural disorders due to use of opioids
0.638 0.362 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.638 0.362 0.000
G30 Alzheimer's disease
0.637 0.362 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.637 0.363 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.636 0.364 0.000
T51.0 Ethanol
0.636 0.364 0.000
I77.8 Other specified disorders of arteries and arterioles
0.635 0.365 0.000
I77.6 Arteritis, unspecified
0.635 0.365 0.000
I77.5 Necrosis of artery
0.635 0.365 0.000
I77.4 Coeliac artery compression syndrome
0.635 0.365 0.000
I77.3 Arterial fibromuscular dysplasia
0.635 0.365 0.000
I77.2 Rupture of artery
0.635 0.365 0.000
I77.0 Arteriovenous fistula, acquired
0.635 0.365 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.635 0.365 0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)
0.635 0.365 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.635 0.365 0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)
0.635 0.365 0.000
M47.94 Spondylosis, unspecified (Thoracic region)
0.635 0.365 0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)
0.635 0.365 0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)
0.635 0.365 0.000
F32 Depressive episode
0.634 0.366 0.000
E15 Nondiabetic hypoglycaemic coma
0.634 0.366 0.000
M65.3 Trigger finger
0.633 0.367 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.632 0.368 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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