TreeWAS – Variant ID: rs6807064

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.019	0.981	0.000
Y42.5 Other oestrogens and progestogens	0.017	0.983	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.016	0.984	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.014	0.986	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.013	0.987	0.000
Y42.2 Antithyroid drugs	0.012	0.988	0.000
Y42.1 Thyroid hormones and substitutes	0.011	0.988	0.000
Y42.9 Other and unspecified hormone antagonists	0.011	0.989	0.000
Y42.4 Oral contraceptives	0.011	0.989	0.000
M06.0 Seronegative rheumatoid arthritis	0.011	0.989	0.000
S92.00 Fracture of calcaneus (closed)	0.000	0.989	0.011
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.011	0.989	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.011	0.989	0.000
C71.9 Brain, unspecified	0.000	0.991	0.009
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.009	0.991	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.009	0.991	0.000
N92.3 Ovulation bleeding	0.009	0.991	0.000
Y42.7 Androgens and anabolic congeners	0.009	0.991	0.000
I27.0 Primary pulmonary hypertension	0.000	0.991	0.009
R47.8 Other and unspecified speech disturbances	0.008	0.992	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.008	0.992	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.008	0.992	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.008	0.992	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.008	0.992	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.008	0.992	0.000
I27.2 Other secondary pulmonary hypertension	0.000	0.992	0.008
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.008	0.992	0.000
S92.0 Fracture of calcaneus	0.000	0.992	0.008
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.008	0.992	0.000
C71 Malignant neoplasm of brain	0.000	0.993	0.007
I27 Other pulmonary heart diseases	0.000	0.993	0.007
C71.3 Parietal lobe	0.000	0.993	0.007
C15.5 Lower third of oesophagus	0.007	0.993	0.000
C71.4 Occipital lobe	0.000	0.993	0.007
C71.0 Cerebrum, except lobes and ventricles	0.000	0.993	0.006
R49.8 Other and unspecified voice disturbances	0.006	0.994	0.000
C15.9 Oesophagus, unspecified	0.006	0.994	0.000
S92.01 Fracture of calcaneus (open)	0.000	0.994	0.006
G51.0 Bell's palsy	0.000	0.994	0.006
C15 Malignant neoplasm of oesophagus	0.006	0.994	0.000
C71.8 Overlapping lesion of brain	0.000	0.994	0.006
Q00-Q07 Congenital malformations of the nervous system	0.006	0.994	0.000
C71.7 Brain stem	0.000	0.994	0.005
C71.6 Cerebellum	0.000	0.994	0.005
Q07 Other congenital malformations of nervous system	0.006	0.994	0.000
S92 Fracture of foot, except ankle	0.000	0.994	0.006
O80.9 Single spontaneous delivery, unspecified	0.000	0.994	0.006
L05.0 Pilonidal cyst with abscess	0.005	0.994	0.000
Q07.0 Arnold-Chiari syndrome	0.005	0.995	0.000
I27.8 Other specified pulmonary heart diseases	0.000	0.995	0.005
Q05 Spina bifida	0.005	0.995	0.000
I27.1 Kyphoscoliotic heart disease	0.000	0.995	0.005
R49 Voice disturbances	0.005	0.995	0.000
J92.0 Pleural plaque with presence of asbestos	0.000	0.995	0.005
S92.7 Multiple fractures of foot	0.000	0.995	0.005
C15.0 Cervical part of oesophagus	0.005	0.995	0.000
Q80-Q89 Other congenital malformations	0.005	0.995	0.000
Q05.9 Spina bifida, unspecified	0.005	0.995	0.000
Z90.2 Acquired absence of lung [part of]	0.000	0.995	0.005
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.005	0.995	0.000
S92.70 Multiple fractures of foot (closed)	0.000	0.995	0.005
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.005	0.995	0.000
C71.5 Cerebral ventricle	0.000	0.995	0.005
Q60.0 Renal agenesis, unilateral	0.005	0.995	0.000
C71.1 Frontal lobe	0.000	0.995	0.005
Q89 Other congenital malformations, not elsewhere classified	0.005	0.995	0.000
S92.4 Fracture of great toe	0.000	0.995	0.005
Q07.8 Other specified congenital malformations of nervous system	0.004	0.995	0.000
S92.2 Fracture of other tarsal bone(s)	0.000	0.995	0.004
Q03 Congenital hydrocephalus	0.004	0.995	0.000
Q60-Q64 Congenital malformations of the urinary system	0.005	0.995	0.000
C15.3 Upper third of oesophagus	0.004	0.995	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.004	0.996	0.000
Q83 Congenital malformations of breast	0.004	0.996	0.000
C15.8 Overlapping lesion of oesophagus	0.004	0.996	0.000
C15.2 Abdominal part of oesophagus	0.004	0.996	0.000
C15.1 Thoracic part of oesophagus	0.004	0.996	0.000
Q05.7 Lumbar spina bifida without hydrocephalus	0.004	0.996	0.000
M10.99 Gout, unspecified (Site unspecified)	0.000	0.996	0.004
M10.9 Gout, unspecified	0.000	0.996	0.004
Q60 Renal agenesis and other reduction defects of kidney	0.004	0.996	0.000
M10.96 Gout, unspecified (Lower leg)	0.000	0.996	0.004
C44.4 Skin of scalp and neck	0.004	0.996	0.000
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.004	0.996	0.000
S92.3 Fracture of metatarsal bone	0.000	0.996	0.004
R49.0 Dysphonia	0.004	0.996	0.000
R49.1 Aphonia	0.004	0.996	0.000
Q06 Other congenital malformations of spinal cord	0.004	0.996	0.000
Q01 Encephalocele	0.004	0.996	0.000
Q00 Anencephaly and similar malformations	0.004	0.996	0.000
Q02 Microcephaly	0.004	0.996	0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.004	0.996	0.000
Q05.4 Unspecified spina bifida with hydrocephalus	0.004	0.996	0.000
Q07.9 Congenital malformation of nervous system, unspecified	0.004	0.996	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.004	0.996	0.000
C71.2 Temporal lobe	0.000	0.996	0.004
S92.9 Fracture of foot, unspecified	0.000	0.996	0.004
M10.94 Gout, unspecified (Hand)	0.000	0.996	0.004
Q04 Other congenital malformations of brain	0.004	0.996	0.000
Q83.1 Accessory breast	0.004	0.996	0.000
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.004	0.996	0.000
O12.1 Gestational proteinuria	0.004	0.996	0.000
Q05.8 Sacral spina bifida without hydrocephalus	0.004	0.996	0.000
Q05.6 Thoracic spina bifida without hydrocephalus	0.004	0.996	0.000
Q05.5 Cervical spina bifida without hydrocephalus	0.004	0.996	0.000
Q05.3 Sacral spina bifida with hydrocephalus	0.004	0.996	0.000
Q05.2 Lumbar spina bifida with hydrocephalus	0.004	0.996	0.000
Q05.1 Thoracic spina bifida with hydrocephalus	0.004	0.996	0.000
Q05.0 Cervical spina bifida with hydrocephalus	0.004	0.996	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.004	0.996	0.000
Q43 Other congenital malformations of intestine	0.004	0.996	0.000
Q50-Q56 Congenital malformations of genital organs	0.004	0.996	0.000
Q89.2 Congenital malformations of other endocrine glands	0.004	0.996	0.000
S92.5 Fracture of other toe	0.000	0.996	0.004
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.004	0.996	0.000
I27.9 Pulmonary heart disease, unspecified	0.000	0.996	0.004
R49.2 Hypernasality and hyponasality	0.004	0.996	0.000
Q45 Other congenital malformations of digestive system	0.004	0.996	0.000
S92.71 Multiple fractures of foot (open)	0.000	0.996	0.004
Q85 Phakomatoses, not elsewhere classified	0.004	0.996	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.004	0.996	0.000
Q84 Other congenital malformations of integument	0.004	0.996	0.000
Q81 Epidermolysis bullosa	0.004	0.996	0.000
Q80 Congenital ichthyosis	0.004	0.996	0.000
Q87.4 Marfan's syndrome	0.004	0.996	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.004	0.996	0.000
Q35-Q37 Cleft lip and cleft palate	0.004	0.996	0.000
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.004	0.996	0.000
Q87.3 Congenital malformation syndromes involving early overgrowth	0.004	0.996	0.000
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.004	0.996	0.000
M50.3 Other cervical disk degeneration	0.000	0.996	0.004
S92.20 Fracture of other tarsal bone(s) (closed)	0.000	0.996	0.004
R47 Speech disturbances, not elsewhere classified	0.004	0.996	0.000
C15.4 Middle third of oesophagus	0.004	0.996	0.000
Q89.3 Situs inversus	0.004	0.996	0.000
S92.40 Fracture of great toe (closed)	0.000	0.996	0.004
Q53 Undescended testicle	0.004	0.996	0.000
M10.90 Gout, unspecified (Multiple sites)	0.000	0.996	0.004
S92.41 Fracture of great toe (open)	0.000	0.996	0.004
M10.93 Gout, unspecified (Forearm)	0.000	0.996	0.004
Q64 Other congenital malformations of urinary system	0.004	0.996	0.000
S92.1 Fracture of talus	0.000	0.996	0.004
Q24 Other congenital malformations of heart	0.004	0.996	0.000
R47-R49 Symptoms and signs involving speech and voice	0.004	0.996	0.000
Q03.0 Malformations of aqueduct of Sylvius	0.003	0.996	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.004	0.996	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.004	0.996	0.000
Q25 Congenital malformations of great arteries	0.004	0.996	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.004	0.996	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.004	0.996	0.000
Q89.9 Congenital malformation, unspecified	0.003	0.996	0.000
Q89.8 Other specified congenital malformations	0.003	0.996	0.000
Q89.7 Multiple congenital malformations, not elsewhere classified	0.003	0.996	0.000
Q89.4 Conjoined twins	0.003	0.996	0.000
Q89.1 Congenital malformations of adrenal gland	0.003	0.996	0.000
Q89.0 Congenital malformations of spleen	0.003	0.996	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.004	0.996	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.003	0.996	0.000
R80 Isolated proteinuria	0.004	0.996	0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance	0.000	0.996	0.004
Q43.0 Meckel's diverticulum	0.004	0.996	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.000	0.996	0.003
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.003	0.996	0.000
M10.92 Gout, unspecified (Upper arm)	0.000	0.996	0.003
T38.8 Other and unspecified hormones and their synthetic substitutes	0.003	0.996	0.000
Q03.9 Congenital hydrocephalus, unspecified	0.003	0.996	0.000
Q03.8 Other congenital hydrocephalus	0.003	0.996	0.000
Q03.1 Atresia of foramina of Magendie and Luschka	0.003	0.996	0.000
S92.30 Fracture of metatarsal bone (closed)	0.000	0.996	0.003
Q43.1 Hirschsprung's disease	0.003	0.996	0.000
Q45.8 Other specified congenital malformations of digestive system	0.003	0.996	0.000
Q83.9 Congenital malformation of breast, unspecified	0.003	0.997	0.000
Q83.3 Accessory nipple	0.003	0.997	0.000
Q83.2 Absent nipple	0.003	0.997	0.000
Q83.0 Congenital absence of breast with absent nipple	0.003	0.997	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.003	0.997	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.003	0.997	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.003	0.997	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.003	0.997	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.003	0.997	0.000
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.003	0.997	0.000
Q60.6 Potter's syndrome	0.003	0.997	0.000
Q60.5 Renal hypoplasia, unspecified	0.003	0.997	0.000
Q60.4 Renal hypoplasia, bilateral	0.003	0.997	0.000
Q60.3 Renal hypoplasia, unilateral	0.003	0.997	0.000
Q60.1 Renal agenesis, bilateral	0.003	0.997	0.000
M10.98 Gout, unspecified (Other)	0.000	0.997	0.003
M10.95 Gout, unspecified (Pelvic region and thigh)	0.000	0.997	0.003
M10.91 Gout, unspecified (Shoulder region)	0.000	0.997	0.003
Q18 Other congenital malformations of face and neck	0.003	0.997	0.000
Q55 Other congenital malformations of male genital organs	0.003	0.997	0.000
S92.31 Fracture of metatarsal bone (open)	0.000	0.997	0.003
Q00.2 Iniencephaly	0.003	0.997	0.000
Q00.1 Craniorachischisis	0.003	0.997	0.000
Q00.0 Anencephaly	0.003	0.997	0.000
Q01.9 Encephalocele, unspecified	0.003	0.997	0.000
Q01.8 Encephalocele of other sites	0.003	0.997	0.000
Q01.2 Occipital encephalocele	0.003	0.997	0.000
Q01.1 Nasofrontal encephalocele	0.003	0.997	0.000
Q01.0 Frontal encephalocele	0.003	0.997	0.000
Q06.9 Congenital malformation of spinal cord, unspecified	0.003	0.997	0.000
Q06.8 Other specified congenital malformations of spinal cord	0.003	0.997	0.000
Q06.4 Hydromyelia	0.003	0.997	0.000
Q06.3 Other congenital cauda equina malformations	0.003	0.997	0.000
Q06.2 Diastematomyelia	0.003	0.997	0.000
Q06.1 Hypoplasia and dysplasia of spinal cord	0.003	0.997	0.000
Q06.0 Amyelia	0.003	0.997	0.000
Q43.3 Congenital malformations of intestinal fixation	0.003	0.997	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.003	0.997	0.000
Q17 Other congenital malformations of ear	0.003	0.997	0.000
Q40 Other congenital malformations of upper alimentary tract	0.003	0.997	0.000
Q39 Congenital malformations of oesophagus	0.003	0.997	0.000
Q26 Congenital malformations of great veins	0.003	0.997	0.000
Q23 Congenital malformations of aortic and mitral valves	0.003	0.997	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.003	0.997	0.000
S92.91 Fracture of foot, unspecified (open)	0.000	0.997	0.003
S92.90 Fracture of foot, unspecified (closed)	0.000	0.997	0.003
Q24.0 Dextrocardia	0.003	0.997	0.000
Q53.9 Undescended testicle, unspecified	0.003	0.997	0.000
Q53.2 Undescended testicle, bilateral	0.003	0.997	0.000
Q04.9 Congenital malformation of brain, unspecified	0.003	0.997	0.000
Q04.8 Other specified congenital malformations of brain	0.003	0.997	0.000
Q04.5 Megalencephaly	0.003	0.997	0.000
Q04.4 Septo-optic dysplasia	0.003	0.997	0.000
Q04.3 Other reduction deformities of brain	0.003	0.997	0.000
Q04.2 Holoprosencephaly	0.003	0.997	0.000
Q04.1 Arhinencephaly	0.003	0.997	0.000
Q04.0 Congenital malformations of corpus callosum	0.003	0.997	0.000
K13.7 Other and unspecified lesions of oral mucosa	0.003	0.997	0.000
Q24.8 Other specified congenital malformations of heart	0.003	0.997	0.000
Q43.7 Persistent cloaca	0.003	0.997	0.000
Q43.6 Congenital fistula of rectum and anus	0.003	0.997	0.000
Q43.5 Ectopic anus	0.003	0.997	0.000
Q43.4 Duplication of intestine	0.003	0.997	0.000
Q43.2 Other congenital functional disorders of colon	0.003	0.997	0.000
R73.9 Hyperglycaemia, unspecified	0.003	0.997	0.000
Q15 Other congenital malformations of eye	0.003	0.997	0.000
Q28 Other congenital malformations of circulatory system	0.003	0.997	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.003	0.997	0.000
Q18.0 Sinus, fistula and cyst of branchial cleft	0.003	0.997	0.000
Q25.6 Stenosis of pulmonary artery	0.003	0.997	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.003	0.997	0.000
R22.2 Localised swelling, mass and lump, trunk	0.003	0.997	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.003	0.997	0.000
Q13 Congenital malformations of anterior segment of eye	0.003	0.997	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.003	0.997	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.003	0.997	0.000
S92.51 Fracture of other toe (open)	0.000	0.997	0.003
Q04.6 Congenital cerebral cysts	0.003	0.997	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.003	0.997	0.000
Q83.8 Other congenital malformations of breast	0.003	0.997	0.000
Q22.5 Ebstein's anomaly	0.003	0.997	0.000
Q45.9 Congenital malformation of digestive system, unspecified	0.003	0.997	0.000
Q45.2 Congenital pancreatic cyst	0.003	0.997	0.000
Q45.1 Annular pancreas	0.003	0.997	0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.003	0.997	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.003	0.997	0.000
T38.0 Glucocorticoids and synthetic analogues	0.003	0.997	0.000
Q63 Other congenital malformations of kidney	0.003	0.997	0.000
S92.50 Fracture of other toe (closed)	0.000	0.997	0.003
Q80.9 Congenital ichthyosis, unspecified	0.003	0.997	0.000
Q80.8 Other congenital ichthyosis	0.003	0.997	0.000
Q80.4 Harlequin foetus	0.003	0.997	0.000
Q80.3 Congenital bullous ichthyosiform erythroderma	0.003	0.997	0.000
Q80.2 Lamellar ichthyosis	0.003	0.997	0.000
Q80.1 X-linked ichthyosis	0.003	0.997	0.000
Q80.0 Ichthyosis vulgaris	0.003	0.997	0.000
Q81.9 Epidermolysis bullosa, unspecified	0.003	0.997	0.000
Q81.8 Other epidermolysis bullosa	0.003	0.997	0.000
Q81.2 Epidermolysis bullosa dystrophica	0.003	0.997	0.000
Q81.1 Epidermolysis bullosa letalis	0.003	0.997	0.000
Q81.0 Epidermolysis bullosa simplex	0.003	0.997	0.000
Q84.9 Congenital malformation of integument, unspecified	0.003	0.997	0.000
Q84.8 Other specified congenital malformations of integument	0.003	0.997	0.000
Q84.6 Other congenital malformations of nails	0.003	0.997	0.000
Q84.5 Enlarged and hypertrophic nails	0.003	0.997	0.000
Q84.4 Congenital leukonychia	0.003	0.997	0.000
Q84.3 Anonychia	0.003	0.997	0.000
Q84.2 Other congenital malformations of hair	0.003	0.997	0.000
Q84.1 Congenital morphological disturbances of hair, not elsewhere classified	0.003	0.997	0.000
Q84.0 Congenital alopecia	0.003	0.997	0.000
Q85.1 Tuberous sclerosis	0.003	0.997	0.000
Q86.8 Other congenital malformation syndromes due to known exogenous causes	0.003	0.997	0.000
Q86.2 Dysmorphism due to warfarin	0.003	0.997	0.000
Q86.1 Foetal hydantoin syndrome	0.003	0.997	0.000
Q86.0 Foetal alcohol syndrome (dysmorphic)	0.003	0.997	0.000
Q14 Congenital malformations of posterior segment of eye	0.003	0.997	0.000
Q21 Congenital malformations of cardiac septa	0.003	0.997	0.000
N99.4 Postprocedural pelvic peritoneal adhesions	0.003	0.997	0.000
L05 Pilonidal cyst	0.003	0.997	0.000
O12.0 Gestational oedema	0.003	0.997	0.000
Q25.4 Other congenital malformations of aorta	0.003	0.997	0.000
Q44.4 Choledochal cyst	0.003	0.997	0.000
Q61.0 Congenital single renal cyst	0.003	0.997	0.000
Q62.2 Congenital megaloureter	0.003	0.997	0.000
Q85.8 Other phakomatoses, not elsewhere classified	0.003	0.997	0.000
Q61 Cystic kidney disease	0.003	0.997	0.000
Q34 Other congenital malformations of respiratory system	0.003	0.997	0.000
Q33 Congenital malformations of lung	0.003	0.997	0.000
Q32 Congenital malformations of trachea and bronchus	0.003	0.997	0.000
Q31 Congenital malformations of larynx	0.003	0.997	0.000
Q30 Congenital malformations of nose	0.003	0.997	0.000
Q37 Cleft palate with cleft lip	0.003	0.997	0.000
Q36 Cleft lip	0.003	0.997	0.000
Q35 Cleft palate	0.003	0.997	0.000
Q43.8 Other specified congenital malformations of intestine	0.003	0.997	0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified	0.003	0.997	0.000
Q21.3 Tetralogy of Fallot	0.003	0.997	0.000
J92 Pleural plaque	0.000	0.997	0.003
Q22.1 Congenital pulmonary valve stenosis	0.003	0.997	0.000
Q53.0 Ectopic testis	0.003	0.997	0.000
Q50.5 Embryonic cyst of broad ligament	0.003	0.997	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.003	0.997	0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.003	0.997	0.000
Q64.9 Congenital malformation of urinary system, unspecified	0.003	0.997	0.000
Q64.8 Other specified congenital malformations of urinary system	0.003	0.997	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.003	0.997	0.000
Q64.6 Congenital diverticulum of bladder	0.003	0.997	0.000
Q64.5 Congenital absence of bladder and urethra	0.003	0.997	0.000
Q64.4 Malformation of urachus	0.003	0.997	0.000
Q64.2 Congenital posterior urethral valves	0.003	0.997	0.000
Q64.1 Exstrophy of urinary bladder	0.003	0.997	0.000
Q64.0 Epispadias	0.003	0.997	0.000
Z73.9 Problem related to life-management difficulty, unspecified	0.003	0.997	0.000
Q82 Other congenital malformations of skin	0.003	0.997	0.000
S92.11 Fracture of talus (open)	0.000	0.997	0.003
K62.0 Anal polyp	0.003	0.997	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.003	0.997	0.000
Q51 Congenital malformations of uterus and cervix	0.003	0.997	0.000
Q24.6 Congenital heart block	0.003	0.997	0.000
Q24.4 Congenital subaortic stenosis	0.003	0.997	0.000
Q24.3 Pulmonary infundibular stenosis	0.003	0.997	0.000
Q24.2 Cor triatriatum	0.003	0.997	0.000
Q24.1 Levocardia	0.003	0.997	0.000
Q52 Other congenital malformations of female genitalia	0.003	0.997	0.000
Q25.1 Coarctation of aorta	0.003	0.997	0.000
Q53.1 Undescended testicle, unilateral	0.003	0.997	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.003	0.997	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.003	0.997	0.000
Q22.6 Hypoplastic right heart syndrome	0.003	0.997	0.000
Q22.4 Congenital tricuspid stenosis	0.003	0.997	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.003	0.997	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.003	0.997	0.000
Q22.0 Pulmonary valve atresia	0.003	0.997	0.000
Q17.5 Prominent ear	0.003	0.997	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.003	0.997	0.000
Q25.8 Other congenital malformations of great arteries	0.003	0.997	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.003	0.997	0.000
Q25.5 Atresia of pulmonary artery	0.003	0.997	0.000
Q25.3 Stenosis of aorta	0.003	0.997	0.000
Q25.2 Atresia of aorta	0.003	0.997	0.000
Q39.4 Oesophageal web	0.003	0.997	0.000
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.003	0.997	0.000
Q50.3 Other congenital malformations of ovary	0.003	0.997	0.000
Q50.2 Congenital torsion of ovary	0.003	0.997	0.000
Q50.1 Developmental ovarian cyst	0.003	0.997	0.000
Q50.0 Congenital absence of ovary	0.003	0.997	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.003	0.997	0.000
T42.0 Hydantoin derivatives	0.003	0.997	0.000
Q12 Congenital lens malformations	0.003	0.997	0.000
L05.9 Pilonidal cyst without abscess	0.003	0.997	0.000
Q24.5 Malformation of coronary vessels	0.003	0.997	0.000
Q62.8 Other congenital malformations of ureter	0.003	0.997	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.003	0.997	0.000
Q62.6 Malposition of ureter	0.003	0.997	0.000
Q62.4 Agenesis of ureter	0.003	0.997	0.000
Q62.1 Atresia and stenosis of ureter	0.003	0.997	0.000
Q62.0 Congenital hydronephrosis	0.003	0.997	0.000
T38.9 Other and unspecified hormone antagonists	0.003	0.997	0.000
T38.7 Androgens and anabolic congeners	0.003	0.997	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.003	0.997	0.000
T38.5 Other oestrogens and progestogens	0.003	0.997	0.000
T38.4 Oral contraceptives	0.003	0.997	0.000
T38.2 Antithyroid drugs	0.003	0.997	0.000
Q96 Turner's syndrome	0.003	0.997	0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.003	0.997	0.000
O12.2 Gestational oedema with proteinuria	0.003	0.997	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.003	0.997	0.000
T38.1 Thyroid hormones and substitutes	0.003	0.997	0.000
Q55.6 Other congenital malformations of penis	0.003	0.997	0.000
J92.9 Pleural plaque without asbestos	0.000	0.997	0.003
Q40.1 Congenital hiatus hernia	0.003	0.997	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.003	0.997	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.003	0.997	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.003	0.997	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.003	0.997	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.003	0.997	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.003	0.997	0.000
Q23.1 Congenital insufficiency of aortic valve	0.003	0.997	0.000
Q23.3 Congenital mitral insufficiency	0.003	0.997	0.000
Q41.9 Congenital absence, atresia and stenosis of small intestine, part unspecified	0.003	0.997	0.000
Q41.8 Congenital absence, atresia and stenosis of other specified parts of small intestine	0.003	0.997	0.000
Q41.2 Congenital absence, atresia and stenosis of ileum	0.003	0.997	0.000
Q41.1 Congenital absence, atresia and stenosis of jejunum	0.003	0.997	0.000
Q41.0 Congenital absence, atresia and stenosis of duodenum	0.003	0.997	0.000
Q42.9 Congenital absence, atresia and stenosis of large intestine, part unspecified	0.003	0.997	0.000
Q42.8 Congenital absence, atresia and stenosis of other parts of large intestine	0.003	0.997	0.000
Q42.3 Congenital absence, atresia and stenosis of anus without fistula	0.003	0.997	0.000
Q42.2 Congenital absence, atresia and stenosis of anus with fistula	0.003	0.997	0.000
Q42.1 Congenital absence, atresia and stenosis of rectum without fistula	0.003	0.997	0.000
Q42.0 Congenital absence, atresia and stenosis of rectum with fistula	0.003	0.997	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.003	0.997	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.003	0.997	0.000
T42.3 Barbiturates	0.003	0.997	0.000
T42.2 Succinimides and oxazolidinediones	0.003	0.997	0.000
Q44.7 Other congenital malformations of liver	0.003	0.997	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.003	0.997	0.000
Q44.2 Atresia of bile ducts	0.003	0.997	0.000
Q44.1 Other congenital malformations of gallbladder	0.003	0.997	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.003	0.997	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.003	0.997	0.000
Q18.9 Congenital malformation of face and neck, unspecified	0.003	0.997	0.000
Q18.8 Other specified congenital malformations of face and neck	0.003	0.997	0.000
Q18.7 Microcheilia	0.003	0.997	0.000
Q18.6 Macrocheilia	0.003	0.997	0.000
Q18.5 Microstomia	0.003	0.997	0.000
Q18.4 Macrostomia	0.003	0.997	0.000
Q18.3 Webbing of neck	0.003	0.997	0.000
Q18.2 Other branchial cleft malformations	0.003	0.997	0.000
Q55.9 Congenital malformation of male genital organ, unspecified	0.003	0.997	0.000
Q55.8 Other specified congenital malformations of male genital organs	0.003	0.997	0.000
Q55.5 Congenital absence and aplasia of penis	0.003	0.997	0.000
Q55.3 Atresia of vas deferens	0.003	0.997	0.000
Q55.1 Hypoplasia of testis and scrotum	0.003	0.997	0.000
Q55.0 Absence and aplasia of testis	0.003	0.997	0.000
Q54 Hypospadias	0.003	0.997	0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.003	0.997	0.000
Q17.9 Congenital malformation of ear, unspecified	0.002	0.997	0.000
Q17.8 Other specified congenital malformations of ear	0.002	0.997	0.000
Q17.4 Misplaced ear	0.002	0.997	0.000
Q17.3 Other misshapen ear	0.002	0.997	0.000
Q17.2 Microtia	0.002	0.997	0.000
Q17.1 Macrotia	0.002	0.997	0.000
Q17.0 Accessory auricle	0.002	0.997	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.002	0.997	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.002	0.997	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.002	0.997	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.002	0.997	0.000
T42.1 Iminostilbenes	0.003	0.997	0.000
Q39.9 Congenital malformation of oesophagus, unspecified	0.002	0.997	0.000
Q39.8 Other congenital malformations of oesophagus	0.002	0.997	0.000
Q39.5 Congenital dilatation of oesophagus	0.002	0.997	0.000
Q39.3 Congenital stenosis and stricture of oesophagus	0.002	0.997	0.000
Q39.2 Congenital tracheooesophageal fistula without atresia	0.002	0.997	0.000
Q39.1 Atresia of oesophagus with tracheooesophageal fistula	0.002	0.997	0.000
Q39.0 Atresia of oesophagus without fistula	0.002	0.997	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.002	0.997	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.002	0.997	0.000
Q20.6 Isomerism of atrial appendages	0.002	0.997	0.000
Q20.5 Discordant atrioventricular connexion	0.002	0.997	0.000
Q20.4 Double inlet ventricle	0.002	0.997	0.000
Q20.3 Discordant ventriculoarterial connexion	0.002	0.997	0.000
Q20.2 Double outlet left ventricle	0.002	0.997	0.000
Q20.1 Double outlet right ventricle	0.002	0.997	0.000
Q20.0 Common arterial trunk	0.002	0.997	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.003	0.997	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.003	0.997	0.000
Q23.4 Hypoplastic left heart syndrome	0.003	0.997	0.000
Q23.2 Congenital mitral stenosis	0.003	0.997	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.002	0.997	0.000
Q26.8 Other congenital malformations of great veins	0.002	0.997	0.000
Q26.6 Portal vein-hepatic artery fistula	0.002	0.997	0.000
Q26.5 Anomalous portal venous connexion	0.002	0.997	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.002	0.997	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.002	0.997	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.002	0.997	0.000
Q26.1 Persistent left superior vena cava	0.002	0.997	0.000
Q26.0 Congenital stenosis of vena cava	0.002	0.997	0.000
Q85.9 Phakomatosis, unspecified	0.002	0.997	0.000
M10.97 Gout, unspecified (Ankle and foot)	0.000	0.997	0.003
E83.4 Disorders of magnesium metabolism	0.003	0.997	0.000
Q15.0 Congenital glaucoma	0.002	0.997	0.000
Q61.4 Renal dysplasia	0.003	0.997	0.000
Q90 Down's syndrome	0.002	0.997	0.000
Q27 Other congenital malformations of peripheral vascular system	0.002	0.997	0.000
Q60.2 Renal agenesis, unspecified	0.002	0.997	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.003	0.997	0.000
Q15.9 Congenital malformation of eye, unspecified	0.002	0.997	0.000
Q15.8 Other specified congenital malformations of eye	0.002	0.997	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.002	0.997	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.002	0.997	0.000
Q28.1 Other malformations of precerebral vessels	0.002	0.997	0.000
Q55.2 Other congenital malformations of testis and scrotum	0.002	0.997	0.000
Q56.4 Indeterminate sex, unspecified	0.002	0.997	0.000
Q56.3 Pseudohermaphroditism, unspecified	0.002	0.997	0.000
Q56.2 Female pseudohermaphroditism, not elsewhere classified	0.002	0.997	0.000
Q56.1 Male pseudohermaphroditism, not elsewhere classified	0.002	0.997	0.000
Q56.0 Hermaphroditism, not elsewhere classified	0.002	0.997	0.000
Q25.0 Patent ductus arteriosus	0.002	0.997	0.000
Q28.3 Other malformations of cerebral vessels	0.002	0.997	0.000
Q44.5 Other congenital malformations of bile ducts	0.002	0.997	0.000
Q63.8 Other specified congenital malformations of kidney	0.002	0.997	0.000
Q10.7 Congenital malformation of orbit	0.002	0.997	0.000
Q10.6 Other congenital malformations of lachrymal apparatus	0.002	0.997	0.000
Q10.5 Congenital stenosis and stricture of lachrymal duct	0.002	0.997	0.000
Q10.4 Absence and agenesis of lachrymal apparatus	0.002	0.997	0.000
Q10.3 Other congenital malformations of eyelid	0.002	0.997	0.000
Q10.2 Congenital entropion	0.002	0.997	0.000
Q10.1 Congenital ectropion	0.002	0.997	0.000
Q10.0 Congenital ptosis	0.002	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations