TreeWAS – Variant ID: rs6808138

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
S82.80 Fractures of other parts of lower leg (closed)	0.140	0.860	0.000
S82.8 Fractures of other parts of lower leg	0.097	0.903	0.000
S82.81 Fractures of other parts of lower leg (open)	0.076	0.924	0.000
S82.86 Maisonneuve's fracture	0.070	0.930	0.000
M10.99 Gout, unspecified (Site unspecified)	0.060	0.940	0.000
S82 Fracture of lower leg, including ankle	0.058	0.942	0.000
S82.6 Fracture of lateral malleolus	0.052	0.948	0.000
S82.7 Multiple fractures of lower leg	0.049	0.951	0.000
S82.2 Fracture of shaft of tibia	0.047	0.953	0.000
S82.60 Fracture of lateral malleolus (closed)	0.046	0.954	0.000
M10.9 Gout, unspecified	0.045	0.955	0.000
M10.97 Gout, unspecified (Ankle and foot)	0.043	0.957	0.000
S82.70 Multiple fractures of lower leg (closed)	0.042	0.958	0.000
S82.9 Fracture of lower leg, part unspecified	0.042	0.958	0.000
S82.61 Fracture of lateral malleolus (open)	0.041	0.959	0.000
S82.4 Fracture of fibula alone	0.041	0.959	0.000
S82.1 Fracture of upper end of tibia	0.040	0.960	0.000
S82.20 Fracture of shaft of tibia (closed)	0.039	0.961	0.000
S82.5 Fracture of medial malleolus	0.037	0.962	0.000
S82.0 Fracture of patella	0.036	0.964	0.000
S82.21 Fracture of shaft of tibia (open)	0.035	0.965	0.000
S82.71 Multiple fractures of lower leg (open)	0.035	0.965	0.000
M10.98 Gout, unspecified (Other)	0.032	0.968	0.000
M10.95 Gout, unspecified (Pelvic region and thigh)	0.032	0.968	0.000
M10.91 Gout, unspecified (Shoulder region)	0.032	0.968	0.000
M10.94 Gout, unspecified (Hand)	0.031	0.969	0.000
S82.91 Fracture of lower leg, part unspecified (open)	0.030	0.970	0.000
S82.90 Fracture of lower leg, part unspecified (closed)	0.030	0.970	0.000
M10.93 Gout, unspecified (Forearm)	0.030	0.970	0.000
M10.90 Gout, unspecified (Multiple sites)	0.030	0.970	0.000
S82.41 Fracture of fibula alone (open)	0.029	0.970	0.000
M10.92 Gout, unspecified (Upper arm)	0.029	0.971	0.000
M10.96 Gout, unspecified (Lower leg)	0.029	0.971	0.000
S82.11 Fracture of upper end of tibia (open)	0.029	0.971	0.000
S82.3 Fracture of lower end of tibia	0.029	0.971	0.000
S82.40 Fracture of fibula alone (closed)	0.029	0.971	0.000
S82.51 Fracture of medial malleolus (open)	0.027	0.973	0.000
S82.01 Fracture of patella (open)	0.027	0.973	0.000
S82.10 Fracture of upper end of tibia (closed)	0.026	0.974	0.000
S82.50 Fracture of medial malleolus (closed)	0.023	0.977	0.000
H04.1 Other disorders of lachrymal gland	0.000	0.977	0.023
M10 Gout	0.022	0.978	0.000
H04 Disorders of lachrymal system	0.000	0.980	0.020
H50 Other strabismus	0.000	0.980	0.020
H50.9 Strabismus, unspecified	0.000	0.981	0.019
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.000	0.981	0.019
S82.00 Fracture of patella (closed)	0.019	0.981	0.000
H49 Paralytic strabismus	0.000	0.982	0.018
H50.1 Divergent concomitant strabismus	0.000	0.982	0.018
H04.3 Acute and unspecified inflammation of lachrymal passages	0.000	0.983	0.017
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.000	0.983	0.017
S82.30 Fracture of lower end of tibia (closed)	0.017	0.983	0.000
H50.0 Convergent concomitant strabismus	0.000	0.983	0.017
J92.0 Pleural plaque with presence of asbestos	0.000	0.983	0.017
H49.2 Sixth [abducent] nerve palsy	0.000	0.983	0.017
M10.4 Other secondary gout	0.016	0.984	0.000
M10.3 Gout due to impairment of renal function	0.016	0.984	0.000
M10.2 Drug-induced gout	0.016	0.984	0.000
M10.1 Lead-induced gout	0.016	0.984	0.000
H04.9 Disorder of lachrymal system, unspecified	0.000	0.984	0.016
M47.86 Other spondylosis (Lumbar region)	0.000	0.984	0.016
H04.4 Chronic inflammation of lachrymal passages	0.000	0.984	0.016
M10.0 Idiopathic gout	0.016	0.984	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.000	0.984	0.016
H52 Disorders of refraction and accommodation	0.000	0.984	0.016
J92.9 Pleural plaque without asbestos	0.000	0.984	0.016
H04.8 Other disorders of lachrymal system	0.000	0.985	0.015
B34.9 Viral infection, unspecified	0.015	0.985	0.000
H05 Disorders of orbit	0.000	0.985	0.015
H49.0 Third [oculomotor] nerve palsy	0.000	0.985	0.015
H04.0 Dacryoadenitis	0.000	0.985	0.015
S82.31 Fracture of lower end of tibia (open)	0.014	0.985	0.000
H50.2 Vertical strabismus	0.000	0.985	0.015
J92 Pleural plaque	0.000	0.985	0.015
H50.6 Mechanical strabismus	0.000	0.985	0.014
H50.4 Other and unspecified heterotropia	0.000	0.985	0.014
H50.3 Intermittent heterotropia	0.000	0.985	0.014
H49.9 Paralytic strabismus, unspecified	0.000	0.985	0.014
H50.8 Other specified strabismus	0.000	0.985	0.014
H52.1 Myopia	0.000	0.985	0.015
H53.2 Diplopia	0.000	0.985	0.015
H04.6 Other changes in lachrymal passages	0.000	0.986	0.014
H04.5 Stenosis and insufficiency of lachrymal passages	0.000	0.986	0.014
H51 Other disorders of binocular movement	0.000	0.986	0.014
H49.1 Fourth [trochlear] nerve palsy	0.000	0.986	0.014
H52.7 Disorder of refraction, unspecified	0.000	0.986	0.013
H05.0 Acute inflammation of orbit	0.000	0.986	0.013
H49.8 Other paralytic strabismus	0.000	0.987	0.013
H49.4 Progressive external ophthalmoplegia	0.000	0.987	0.013
H49.3 Total (external) ophthalmoplegia	0.000	0.987	0.013
H04.2 Epiphora	0.000	0.987	0.013
H05.8 Other disorders of orbit	0.000	0.987	0.013
H01 Other inflammation of eyelid	0.000	0.987	0.013
H03 Disorders of eyelid in diseases classified elsewhere	0.000	0.987	0.013
Q61.2 Polycystic kidney, adult type	0.012	0.988	0.000
H50.5 Heterophoria	0.000	0.988	0.012
H00 Hordeolum and chalazion	0.000	0.988	0.012
H52.0 Hypermetropia	0.000	0.988	0.012
Chapter VII Diseases of the eye and adnexa	0.000	0.988	0.012
M10.19 Lead-induced gout (Site unspecified)	0.012	0.988	0.000
M10.18 Lead-induced gout (Other)	0.012	0.988	0.000
M10.17 Lead-induced gout (Ankle and foot)	0.012	0.988	0.000
M10.16 Lead-induced gout (Lower leg)	0.012	0.988	0.000
M10.15 Lead-induced gout (Pelvic region and thigh)	0.012	0.988	0.000
M10.14 Lead-induced gout (Hand)	0.012	0.988	0.000
M10.13 Lead-induced gout (Forearm)	0.012	0.988	0.000
M10.12 Lead-induced gout (Upper arm)	0.012	0.988	0.000
M10.11 Lead-induced gout (Shoulder region)	0.012	0.988	0.000
M10.10 Lead-induced gout (Multiple sites)	0.012	0.988	0.000
M10.29 Drug-induced gout (Site unspecified)	0.012	0.988	0.000
M10.28 Drug-induced gout (Other)	0.012	0.988	0.000
M10.27 Drug-induced gout (Ankle and foot)	0.012	0.988	0.000
M10.26 Drug-induced gout (Lower leg)	0.012	0.988	0.000
M10.25 Drug-induced gout (Pelvic region and thigh)	0.012	0.988	0.000
M10.24 Drug-induced gout (Hand)	0.012	0.988	0.000
M10.23 Drug-induced gout (Forearm)	0.012	0.988	0.000
M10.22 Drug-induced gout (Upper arm)	0.012	0.988	0.000
M10.21 Drug-induced gout (Shoulder region)	0.012	0.988	0.000
M10.20 Drug-induced gout (Multiple sites)	0.012	0.988	0.000
M10.39 Gout due to impairment of renal function (Site unspecified)	0.012	0.988	0.000
M10.38 Gout due to impairment of renal function (Other)	0.012	0.988	0.000
M10.37 Gout due to impairment of renal function (Ankle and foot)	0.012	0.988	0.000
M10.36 Gout due to impairment of renal function (Lower leg)	0.012	0.988	0.000
M10.35 Gout due to impairment of renal function (Pelvic region and thigh)	0.012	0.988	0.000
M10.34 Gout due to impairment of renal function (Hand)	0.012	0.988	0.000
M10.33 Gout due to impairment of renal function (Forearm)	0.012	0.988	0.000
M10.32 Gout due to impairment of renal function (Upper arm)	0.012	0.988	0.000
M10.31 Gout due to impairment of renal function (Shoulder region)	0.012	0.988	0.000
M10.30 Gout due to impairment of renal function (Multiple sites)	0.012	0.988	0.000
M10.49 Other secondary gout (Site unspecified)	0.012	0.988	0.000
M10.48 Other secondary gout (Other)	0.012	0.988	0.000
M10.47 Other secondary gout (Ankle and foot)	0.012	0.988	0.000
M10.46 Other secondary gout (Lower leg)	0.012	0.988	0.000
M10.45 Other secondary gout (Pelvic region and thigh)	0.012	0.988	0.000
M10.44 Other secondary gout (Hand)	0.012	0.988	0.000
M10.43 Other secondary gout (Forearm)	0.012	0.988	0.000
M10.42 Other secondary gout (Upper arm)	0.012	0.988	0.000
M10.41 Other secondary gout (Shoulder region)	0.012	0.988	0.000
M10.40 Other secondary gout (Multiple sites)	0.012	0.988	0.000
Q18.1 Preauricular sinus and cyst	0.012	0.988	0.000
M10.09 Idiopathic gout (Site unspecified)	0.012	0.988	0.000
M10.08 Idiopathic gout (Other)	0.012	0.988	0.000
M10.06 Idiopathic gout (Lower leg)	0.012	0.988	0.000
M10.05 Idiopathic gout (Pelvic region and thigh)	0.012	0.988	0.000
M10.04 Idiopathic gout (Hand)	0.012	0.988	0.000
M10.03 Idiopathic gout (Forearm)	0.012	0.988	0.000
M10.02 Idiopathic gout (Upper arm)	0.012	0.988	0.000
M10.01 Idiopathic gout (Shoulder region)	0.012	0.988	0.000
M10.00 Idiopathic gout (Multiple sites)	0.012	0.988	0.000
H52.6 Other disorders of refraction	0.000	0.988	0.012
H52.5 Disorders of accommodation	0.000	0.988	0.012
H52.4 Presbyopia	0.000	0.988	0.012
M10.07 Idiopathic gout (Ankle and foot)	0.011	0.989	0.000
H05.2 Exophthalmic conditions	0.000	0.989	0.011
Q61 Cystic kidney disease	0.011	0.989	0.000
M47.82 Other spondylosis (Cervical region)	0.000	0.989	0.011
M47.8 Other spondylosis	0.000	0.989	0.011
H05.9 Disorder of orbit, unspecified	0.000	0.989	0.011
H05.5 Retained (old) foreign body following penetrating wound of orbit	0.000	0.989	0.011
H05.4 Enophthalmos	0.000	0.989	0.011
H05.3 Deformity of orbit	0.000	0.989	0.011
H05.1 Chronic inflammatory disorders of orbit	0.000	0.989	0.011
I35.0 Aortic (valve) stenosis	0.000	0.989	0.011
H53-H54 Visual disturbances and blindness	0.000	0.989	0.011
H01.0 Blepharitis	0.000	0.989	0.010
Q18 Other congenital malformations of face and neck	0.010	0.990	0.000
Q61.3 Polycystic kidney, unspecified	0.010	0.990	0.000
H03.1 Involvement of eyelid in other infectious diseases classified elsewhere	0.000	0.990	0.010
H51.9 Disorder of binocular movement, unspecified	0.000	0.990	0.010
H51.8 Other specified disorders of binocular movement	0.000	0.990	0.010
H51.2 Internuclear ophthalmoplegia	0.000	0.990	0.010
H51.1 Convergence insufficiency and excess	0.000	0.990	0.010
H51.0 Palsy of conjugate gaze	0.000	0.990	0.010
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.000	0.990	0.010
H46-H48 Disorders of optic nerve and visual pathways	0.000	0.990	0.010
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.010	0.990	0.000
H00.1 Chalazion	0.000	0.990	0.010
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.010	0.990	0.000
Q60-Q64 Congenital malformations of the urinary system	0.010	0.990	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.010	0.990	0.000
H01.8 Other specified inflammation of eyelid	0.000	0.990	0.009
I35.9 Aortic valve disorder, unspecified	0.000	0.991	0.009
I35 Nonrheumatic aortic valve disorders	0.000	0.991	0.009
H55-H59 Other disorders of eye and adnexa	0.000	0.991	0.009
H01.1 Non-infectious dermatoses of eyelid	0.000	0.991	0.009
H03.8 Involvement of eyelid in other diseases classified elsewhere	0.000	0.991	0.009
H03.0 Parasitic infestation of eyelid in diseases classified elsewhere	0.000	0.991	0.009
I35.1 Aortic (valve) insufficiency	0.000	0.991	0.009
Q66 Congenital deformities of feet	0.009	0.991	0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.000	0.991	0.009
H55 Nystagmus and other irregular eye movements	0.000	0.991	0.009
H52.2 Astigmatism	0.000	0.991	0.009
H10-H13 Disorders of conjunctiva	0.000	0.991	0.009
H43-H45 Disorders of vitreous body and globe	0.000	0.991	0.009
M47.87 Other spondylosis (Lumbosacral region)	0.000	0.991	0.009
H01.9 Inflammation of eyelid, unspecified	0.000	0.991	0.009
H53 Visual disturbances	0.000	0.991	0.009
H46 Optic neuritis	0.000	0.991	0.009
H00.0 Hordeolum and other deep inflammation of eyelid	0.000	0.991	0.009
Q74 Other congenital malformations of limb(s)	0.009	0.991	0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.000	0.991	0.009
H54 Blindness and low vision	0.000	0.991	0.009
Q76 Congenital malformations of spine and bony thorax	0.008	0.992	0.000
Q61.5 Medullary cystic kidney	0.008	0.992	0.000
Q61.9 Cystic kidney disease, unspecified	0.008	0.992	0.000
Q61.8 Other cystic kidney diseases	0.008	0.992	0.000
Q61.4 Renal dysplasia	0.008	0.992	0.000
Q61.1 Polycystic kidney, infantile type	0.008	0.992	0.000
H44 Disorders of globe	0.000	0.992	0.008
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.008	0.992	0.000
Q80-Q89 Other congenital malformations	0.008	0.992	0.000
M47.83 Other spondylosis (Cervicothoracic region)	0.000	0.992	0.008
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.000	0.992	0.008
M47.84 Other spondylosis (Thoracic region)	0.000	0.992	0.008
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.008	0.992	0.000
H52.3 Anisometropia and aniseikonia	0.000	0.992	0.008
Q38-Q45 Other congenital malformations of the digestive system	0.008	0.992	0.000
B34 Viral infection of unspecified site	0.008	0.992	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.008	0.992	0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified	0.000	0.992	0.008
M47.89 Other spondylosis (Site unspecified)	0.000	0.992	0.008
Q66.9 Congenital deformity of feet, unspecified	0.008	0.992	0.000
Q78 Other osteochondrodysplasias	0.008	0.992	0.000
M06.0 Seronegative rheumatoid arthritis	0.008	0.992	0.000
H11 Other disorders of conjunctiva	0.000	0.992	0.008
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.008	0.992	0.000
H44.0 Purulent endophthalmitis	0.000	0.992	0.008
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.008	0.992	0.000
Q18.9 Congenital malformation of face and neck, unspecified	0.008	0.992	0.000
Q18.8 Other specified congenital malformations of face and neck	0.008	0.992	0.000
Q18.7 Microcheilia	0.008	0.992	0.000
Q18.6 Macrocheilia	0.008	0.992	0.000
Q18.5 Microstomia	0.008	0.992	0.000
Q18.4 Macrostomia	0.008	0.992	0.000
Q18.3 Webbing of neck	0.008	0.992	0.000
Q18.2 Other branchial cleft malformations	0.008	0.992	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.000	0.992	0.008
Q66.3 Other congenital varus deformities of feet	0.008	0.992	0.000
Q76.1 Klippel-Feil syndrome	0.008	0.992	0.000
H54.4 Blindness, one eye	0.000	0.992	0.008
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere	0.000	0.992	0.007
H06.3 Other disorders of orbit in diseases classified elsewhere	0.000	0.992	0.007
H06.1 Parasitic infestation of orbit in diseases classified elsewhere	0.000	0.992	0.007
H06.0 Disorders of lachrymal system in diseases classified elsewhere	0.000	0.992	0.007
H47 Other disorders of optic [2nd] nerve and visual pathways	0.000	0.992	0.007
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.007	0.992	0.000
Q75 Other congenital malformations of skull and face bones	0.007	0.992	0.000
Q73 Reduction defects of unspecified limb	0.007	0.992	0.000
Q72 Reduction defects of lower limb	0.007	0.992	0.000
Q71 Reduction defects of upper limb	0.007	0.992	0.000
Q70 Syndactyly	0.007	0.992	0.000
Q69 Polydactyly	0.007	0.992	0.000
Q68 Other congenital musculoskeletal deformities	0.007	0.992	0.000
G93.3 Postviral fatigue syndrome	0.000	0.992	0.008
Q17 Other congenital malformations of ear	0.007	0.993	0.000
Q66.0 Talipes equinovarus	0.007	0.993	0.000
N75.0 Cyst of Bartholin's gland	0.007	0.993	0.000
Q18.0 Sinus, fistula and cyst of branchial cleft	0.007	0.993	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.007	0.993	0.000
Q15 Other congenital malformations of eye	0.007	0.993	0.000
Q14 Congenital malformations of posterior segment of eye	0.007	0.993	0.000
Q13 Congenital malformations of anterior segment of eye	0.007	0.993	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.007	0.993	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.007	0.993	0.000
H11.3 Conjunctival haemorrhage	0.000	0.993	0.007
Q66.7 Pes cavus	0.007	0.993	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.007	0.993	0.000
M05-M14 Inflammatory polyarthropathies	0.007	0.993	0.000
Q64 Other congenital malformations of urinary system	0.007	0.993	0.000
Q35-Q37 Cleft lip and cleft palate	0.007	0.993	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.007	0.993	0.000
Q82 Other congenital malformations of skin	0.007	0.993	0.000
H54.7 Unspecified visual loss	0.000	0.993	0.007
Q66.2 Metatarsus varus	0.007	0.993	0.000
Q79.6 Ehlers-Danlos syndrome	0.007	0.993	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.007	0.993	0.000
Q00-Q07 Congenital malformations of the nervous system	0.007	0.993	0.000
M47.80 Other spondylosis (Multiple sites in spine)	0.000	0.993	0.007
Q66.6 Other congenital valgus deformities of feet	0.007	0.993	0.000
Q66.5 Congenital pes planus	0.007	0.993	0.000
Q66.4 Talipes calcaneovalgus	0.007	0.993	0.000
Q66.1 Talipes calcaneovarus	0.007	0.993	0.000
N31.1 Reflex neuropathic bladder, not elsewhere classified	0.000	0.993	0.007
N31.0 Uninhibited neuropathic bladder, not elsewhere classified	0.000	0.993	0.007
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.007	0.993	0.000
Q12 Congenital lens malformations	0.007	0.993	0.000
Q66.8 Other congenital deformities of feet	0.007	0.993	0.000
H44.2 Degenerative myopia	0.000	0.993	0.007
Q90 Down's syndrome	0.007	0.993	0.000
N31.8 Other neuromuscular dysfunction of bladder	0.000	0.993	0.007
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.007	0.993	0.000
Q83 Congenital malformations of breast	0.007	0.993	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.007	0.993	0.000
M47.85 Other spondylosis (Thoracolumbar region)	0.000	0.993	0.006
H13 Disorders of conjunctiva in diseases classified elsewhere	0.000	0.993	0.006
H47.2 Optic atrophy	0.000	0.993	0.007
H53.0 Amblyopia ex anopsia	0.000	0.993	0.007
H54.0 Blindness, both eyes	0.000	0.993	0.007
H11.1 Conjunctival degenerations and deposits	0.000	0.993	0.007
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.007	0.993	0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.000	0.993	0.006
Q65 Congenital deformities of hip	0.006	0.993	0.000
H53.6 Night blindness	0.000	0.993	0.006
H53.5 Colour vision deficiencies	0.000	0.993	0.006
H53.3 Other disorders of binocular vision	0.000	0.993	0.006
M06 Other rheumatoid arthritis	0.007	0.993	0.000
Q74.9 Unspecified congenital malformation of limb(s)	0.006	0.993	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.006	0.993	0.000
Q74.3 Arthrogryposis multiplex congenita	0.006	0.993	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.006	0.993	0.000
Q61.0 Congenital single renal cyst	0.006	0.993	0.000
Q45 Other congenital malformations of digestive system	0.006	0.993	0.000
H54.6 Unqualified visual loss, one eye	0.000	0.994	0.006
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.994	0.006
H54.3 Unqualified visual loss, both eyes	0.000	0.994	0.006
H54.2 Low vision, both eyes	0.000	0.994	0.006
H54.1 Blindness, one eye, low vision, other eye	0.000	0.994	0.006
Q74.1 Congenital malformation of knee	0.006	0.994	0.000
X41.9 Unspecified place	0.006	0.994	0.000
Q40 Other congenital malformations of upper alimentary tract	0.006	0.994	0.000
H54.5 Low vision, one eye	0.000	0.994	0.006
Q76.9 Congenital malformation of bony thorax, unspecified	0.006	0.994	0.000
Q76.8 Other congenital malformations of bony thorax	0.006	0.994	0.000
Q76.7 Congenital malformation of sternum	0.006	0.994	0.000
Q76.6 Other congenital malformations of ribs	0.006	0.994	0.000
Q76.5 Cervical rib	0.006	0.994	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.006	0.994	0.000
Q76.2 Congenital spondylolisthesis	0.006	0.994	0.000
B34.4 Papovirus infection, unspecified	0.006	0.994	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.006	0.994	0.000
H44.1 Other endophthalmitis	0.000	0.994	0.006
N87.1 Moderate cervical dysplasia	0.000	0.994	0.006
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.000	0.994	0.006
Q43 Other congenital malformations of intestine	0.006	0.994	0.000
H44.9 Disorder of globe, unspecified	0.000	0.994	0.006
H44.8 Other disorders of globe	0.000	0.994	0.006
H44.7 Retained (old) intraocular foreign body, nonmagnetic	0.000	0.994	0.006
H44.6 Retained (old) intraocular foreign body, magnetic	0.000	0.994	0.006
H44.5 Degenerated conditions of globe	0.000	0.994	0.006
H44.4 Hypotony of eye	0.000	0.994	0.006
H44.3 Other degenerative disorders of globe	0.000	0.994	0.006
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.006	0.994	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.006	0.994	0.000
Q79.5 Other congenital malformations of abdominal wall	0.006	0.994	0.000
Q79.4 Prune belly syndrome	0.006	0.994	0.000
Q79.3 Gastroschisis	0.006	0.994	0.000
Q79.2 Exomphalos	0.006	0.994	0.000
Q79.1 Other congenital malformations of diaphragm	0.006	0.994	0.000
Q79.0 Congenital diaphragmatic hernia	0.006	0.994	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.006	0.994	0.000
Q84 Other congenital malformations of integument	0.006	0.994	0.000
Q81 Epidermolysis bullosa	0.006	0.994	0.000
Q80 Congenital ichthyosis	0.006	0.994	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.006	0.994	0.000
Q78.0 Osteogenesis imperfecta	0.006	0.994	0.000
Q89 Other congenital malformations, not elsewhere classified	0.006	0.994	0.000
Q96 Turner's syndrome	0.006	0.994	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.006	0.994	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.006	0.994	0.000
Q67.5 Congenital deformity of spine	0.006	0.994	0.000
B34.3 Parvovirus infection, unspecified	0.006	0.994	0.000
B34.2 Coronavirus infection, unspecified	0.006	0.994	0.000
B34.1 Enterovirus infection, unspecified	0.006	0.994	0.000
B34.0 Adenovirus infection, unspecified	0.006	0.994	0.000
Q82.0 Hereditary lymphoedema	0.006	0.994	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.006	0.994	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.006	0.994	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.006	0.994	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.006	0.994	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.006	0.994	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.006	0.994	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.006	0.994	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.006	0.994	0.000
B34.8 Other viral infections of unspecified site	0.006	0.994	0.000
H06.2 Dysthyroid exophthalmos	0.000	0.994	0.006
M12 Other specific arthropathies	0.006	0.994	0.000
Q78.9 Osteochondrodysplasia, unspecified	0.006	0.994	0.000
Q78.8 Other specified osteochondrodysplasias	0.006	0.994	0.000
Q78.6 Multiple congenital exostoses	0.006	0.994	0.000
Q78.5 Metaphyseal dysplasia	0.006	0.994	0.000
Q78.4 Enchondromatosis	0.006	0.994	0.000
Q78.3 Progressive diaphyseal dysplasia	0.006	0.994	0.000
Q78.2 Osteopetrosis	0.006	0.994	0.000
Q78.1 Polyostotic fibrous dysplasia	0.006	0.994	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.006	0.994	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.006	0.994	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.006	0.994	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.006	0.994	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.006	0.994	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.006	0.994	0.000
Q90.9 Down's syndrome, unspecified	0.006	0.994	0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.000	0.994	0.006
Q67.8 Other congenital deformities of chest	0.006	0.994	0.000
Q67.7 Pectus carinatum	0.006	0.994	0.000
Q67.6 Pectus excavatum	0.006	0.994	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.006	0.994	0.000
Q67.3 Plagiocephaly	0.006	0.994	0.000
Q67.2 Dolichocephaly	0.006	0.994	0.000
Q67.1 Compression facies	0.006	0.994	0.000
Q67.0 Facial asymmetry	0.006	0.994	0.000
Q87.4 Marfan's syndrome	0.006	0.994	0.000
Q07 Other congenital malformations of nervous system	0.006	0.994	0.000
H47.3 Other disorders of optic disk	0.000	0.994	0.006
H53.4 Visual field defects	0.000	0.994	0.006
Q82.5 Congenital nonneoplastic naevus	0.006	0.994	0.000
Q39 Congenital malformations of oesophagus	0.006	0.994	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.000	0.994	0.006
Q44.6 Cystic disease of liver	0.006	0.994	0.000
H48.8 Other disorders of optic nerve and visual pathways in diseases classified elsewhere	0.000	0.994	0.005
H48.1 Retrobulbar neuritis in diseases classified elsewhere	0.000	0.994	0.005
H48.0 Optic atrophy in diseases classified elsewhere	0.000	0.994	0.005
M11 Other crystal arthropathies	0.006	0.994	0.000
H47.7 Disorder of visual pathways, unspecified	0.000	0.994	0.006
H47.6 Disorders of visual cortex	0.000	0.994	0.006
H47.5 Disorders of other visual pathways	0.000	0.994	0.006
H47.4 Disorders of optic chiasm	0.000	0.994	0.006
Q68.8 Other specified congenital musculoskeletal deformities	0.005	0.994	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.005	0.994	0.000
Q68.4 Congenital bowing of tibia and fibula	0.005	0.994	0.000
Q68.3 Congenital bowing of femur	0.005	0.994	0.000
Q68.2 Congenital deformity of knee	0.005	0.994	0.000
Q68.1 Congenital deformity of hand	0.005	0.994	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.005	0.994	0.000
Q69.9 Polydactyly, unspecified	0.005	0.994	0.000
Q69.2 Accessory toe(s)	0.005	0.994	0.000
Q69.1 Accessory thumb(s)	0.005	0.994	0.000
Q69.0 Accessory finger(s)	0.005	0.994	0.000
Q70.9 Syndactyly, unspecified	0.005	0.994	0.000
Q70.4 Polysyndactyly	0.005	0.994	0.000
Q70.3 Webbed toes	0.005	0.994	0.000
Q70.2 Fused toes	0.005	0.994	0.000
Q70.1 Webbed fingers	0.005	0.994	0.000
Q70.0 Fused fingers	0.005	0.994	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.005	0.994	0.000
Q71.8 Other reduction defects of upper limb(s)	0.005	0.994	0.000
Q71.6 Lobster-claw hand	0.005	0.994	0.000
Q71.5 Longitudinal reduction defect of ulna	0.005	0.994	0.000
Q71.4 Longitudinal reduction defect of radius	0.005	0.994	0.000
Q71.3 Congenital absence of hand and finger(s)	0.005	0.994	0.000
Q71.2 Congenital absence of both forearm and hand	0.005	0.994	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.005	0.994	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.005	0.994	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.005	0.994	0.000
Q72.8 Other reduction defects of lower limb(s)	0.005	0.994	0.000
Q72.7 Split foot	0.005	0.994	0.000
Q72.6 Longitudinal reduction defect of fibula	0.005	0.994	0.000
Q72.5 Longitudinal reduction defect of tibia	0.005	0.994	0.000
Q72.4 Longitudinal reduction defect of femur	0.005	0.994	0.000
Q72.3 Congenital absence of foot and toe(s)	0.005	0.994	0.000
Q72.2 Congenital absence of both lower leg and foot	0.005	0.994	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.005	0.994	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.005	0.994	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.005	0.994	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.005	0.994	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.005	0.994	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.005	0.994	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.005	0.994	0.000
Q75.5 Oculomandibular dysostosis	0.005	0.994	0.000
Q75.4 Mandibulofacial dysostosis	0.005	0.994	0.000
Q75.3 Macrocephaly	0.005	0.994	0.000
Q75.2 Hypertelorism	0.005	0.994	0.000
Q75.1 Craniofacial dysostosis	0.005	0.994	0.000
Q75.0 Craniosynostosis	0.005	0.994	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.005	0.994	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.005	0.994	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.005	0.994	0.000
Q77.6 Chondroectodermal dysplasia	0.005	0.994	0.000
Q77.5 Diastrophic dysplasia	0.005	0.994	0.000
Q77.4 Achondroplasia	0.005	0.994	0.000
Q77.3 Chondrodysplasia punctata	0.005	0.994	0.000
Q77.2 Short rib syndrome	0.005	0.994	0.000
Q77.1 Thanatophoric short stature	0.005	0.994	0.000
Q77.0 Achondrogenesis	0.005	0.994	0.000
Q17.5 Prominent ear	0.005	0.994	0.000
Q83.8 Other congenital malformations of breast	0.006	0.994	0.000
Q43.1 Hirschsprung's disease	0.006	0.994	0.000
M14 Arthropathies in other diseases classified elsewhere	0.006	0.994	0.000
Q17.9 Congenital malformation of ear, unspecified	0.005	0.994	0.000
Q17.8 Other specified congenital malformations of ear	0.005	0.994	0.000
Q17.4 Misplaced ear	0.005	0.994	0.000
Q17.3 Other misshapen ear	0.005	0.994	0.000
Q17.2 Microtia	0.005	0.994	0.000
Q17.1 Macrotia	0.005	0.994	0.000
Q17.0 Accessory auricle	0.005	0.994	0.000
H40-H42 Glaucoma	0.000	0.994	0.006
H11.0 Pterygium	0.000	0.994	0.005
Q60.2 Renal agenesis, unspecified	0.005	0.994	0.000
Q10.7 Congenital malformation of orbit	0.005	0.994	0.000
Q10.6 Other congenital malformations of lachrymal apparatus	0.005	0.994	0.000
Q10.5 Congenital stenosis and stricture of lachrymal duct	0.005	0.994	0.000
Q10.4 Absence and agenesis of lachrymal apparatus	0.005	0.994	0.000
Q10.3 Other congenital malformations of eyelid	0.005	0.994	0.000
Q10.2 Congenital entropion	0.005	0.994	0.000
Q10.1 Congenital ectropion	0.005	0.994	0.000
Q10.0 Congenital ptosis	0.005	0.994	0.000
Q11.3 Macrophthalmos	0.005	0.994	0.000
Q11.2 Microphthalmos	0.005	0.994	0.000
Q11.1 Other anophthalmos	0.005	0.994	0.000
Q11.0 Cystic eyeball	0.005	0.994	0.000
Q13.9 Congenital malformation of anterior segment of eye, unspecified	0.005	0.994	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations