TreeWAS – Variant ID: rs6831256

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
S22.40 Multiple fractures of ribs (closed)	0.000	0.937	0.063
S22.4 Multiple fractures of ribs	0.000	0.945	0.055
S22 Fracture of rib(s), sternum and thoracic spine	0.000	0.952	0.048
S22.1 Multiple fractures of thoracic spine	0.000	0.956	0.044
S22.5 Flail chest	0.000	0.957	0.043
S22.10 Multiple fractures of thoracic spine (closed)	0.000	0.959	0.041
S22.41 Multiple fractures of ribs (open)	0.000	0.961	0.039
S22.50 Flail chest (closed)	0.000	0.961	0.039
S22.2 Fracture of sternum	0.000	0.965	0.035
S22.9 Fracture of bony thorax, part unspecified	0.000	0.965	0.035
S22.8 Fracture of other parts of bony thorax	0.000	0.965	0.035
S22.0 Fracture of thoracic vertebra	0.000	0.965	0.035
S22.3 Fracture of rib	0.000	0.968	0.032
S22.11 Multiple fractures of thoracic spine (open)	0.000	0.968	0.031
S22.51 Flail chest (open)	0.000	0.969	0.031
S22.20 Fracture of sternum (closed)	0.000	0.974	0.025
S22.21 Fracture of sternum (open)	0.000	0.975	0.025
S22.81 Fracture of other parts of bony thorax (open)	0.000	0.975	0.025
S22.80 Fracture of other parts of bony thorax (closed)	0.000	0.975	0.025
S22.91 Fracture of bony thorax, part unspecified (open)	0.000	0.975	0.025
S22.90 Fracture of bony thorax, part unspecified (closed)	0.000	0.975	0.025
S22.01 Fracture of thoracic vertebra (open)	0.000	0.975	0.025
S22.00 Fracture of thoracic vertebra (closed)	0.000	0.975	0.025
S20-S29 Injuries to the thorax	0.000	0.975	0.024
S22.31 Fracture of rib (open)	0.000	0.977	0.023
S27 Injury of other and unspecified intrathoracic organs	0.000	0.978	0.022
S21 Open wound of thorax	0.000	0.979	0.021
S22.30 Fracture of rib (closed)	0.000	0.980	0.020
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.000	0.981	0.019
S21.9 Open wound of thorax, part unspecified	0.000	0.982	0.018
S27.0 Traumatic pneumothorax	0.000	0.982	0.018
S24 Injury of nerves and spinal cord at thorax level	0.000	0.982	0.018
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.000	0.982	0.018
S26 Injury of heart	0.000	0.982	0.018
S25 Injury of blood vessels of thorax	0.000	0.982	0.018
S27.8 Injury of other specified intrathoracic organs	0.000	0.982	0.018
S27.3 Other injuries of lung	0.000	0.982	0.017
S21.1 Open wound of front wall of thorax	0.000	0.983	0.017
S27.2 Traumatic heamopneumothorax	0.000	0.983	0.017
S42.00 Fracture of clavicle (closed)	0.000	0.983	0.017
S27.9 Injury of unspecified intrathoracic organ	0.000	0.984	0.016
S27.7 Multiple injuries of intrathoracic organs	0.000	0.984	0.016
S27.6 Injury of pleura	0.000	0.984	0.016
S27.5 Injury of thoracic trachea	0.000	0.984	0.016
S27.4 Injury of bronchus	0.000	0.984	0.016
S27.1 Traumatic haemothorax	0.000	0.984	0.016
S29 Other and unspecified injuries of thorax	0.000	0.984	0.016
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.000	0.984	0.016
S21.8 Open wound of other parts of thorax	0.000	0.984	0.015
S21.7 Multiple open wounds of thoracic wall	0.000	0.984	0.015
S21.0 Open wound of breast	0.000	0.984	0.015
S21.2 Open wound of back wall of thorax	0.000	0.985	0.015
S27.80 Injury of other specified intrathoracic organs (without open wound into thoracic cavity)	0.000	0.985	0.014
S23.4 Sprain and strain of ribs and sternum	0.000	0.985	0.014
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.000	0.986	0.014
S23.5 Sprain and strain of other and unspecified parts of thorax	0.000	0.986	0.013
S23.3 Sprain and strain of thoracic spine	0.000	0.986	0.013
S23.2 Dislocation of other and unspecified parts of thorax	0.000	0.986	0.013
S23.1 Dislocation of thoracic vertebra	0.000	0.986	0.013
S23.0 Traumatic rupture of thoracic intervertebral disk	0.000	0.986	0.013
S06.20 Diffuse brain injury (without open intracranial wound)	0.000	0.986	0.014
S24.1 Other and unspecified injuries of thoracic spinal cord	0.000	0.987	0.013
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.000	0.987	0.013
S24.6 Injury of unspecified nerve of thorax	0.000	0.987	0.013
S24.5 Injury of other nerves of thorax	0.000	0.987	0.013
S24.4 Injury of thoracic sympathetic nerves	0.000	0.987	0.013
S24.3 Injury of peripheral nerves of thorax	0.000	0.987	0.013
S24.2 Injury of nerve root of thoracic spine	0.000	0.987	0.013
S24.0 Concussion and oedema of thoracic spinal cord	0.000	0.987	0.013
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.000	0.987	0.013
S25.9 Injury of unspecified blood vessel of thorax	0.000	0.987	0.013
S25.8 Injury of other blood vessels of thorax	0.000	0.987	0.013
S25.7 Injury of multiple blood vessels of thorax	0.000	0.987	0.013
S25.5 Injury of intercostal blood vessels	0.000	0.987	0.013
S25.4 Injury of pulmonary blood vessels	0.000	0.987	0.013
S25.3 Injury of innominate or subclavian vein	0.000	0.987	0.013
S25.2 Injury of superior vena cava	0.000	0.987	0.013
S25.1 Injury of innominate or subclavian artery	0.000	0.987	0.013
S25.0 Injury of thoracic aorta	0.000	0.987	0.013
S26.9 Injury of heart, unspecified	0.000	0.987	0.013
S26.8 Other injuries of heart	0.000	0.987	0.013
S26.0 Injury of heart with haemopericardium	0.000	0.987	0.013
S28.1 Traumatic amputation of part of thorax	0.000	0.987	0.013
S28.0 Crushed chest	0.000	0.987	0.013
M25.47 Effusion of joint (Ankle and foot)	0.013	0.987	0.000
S27.81 Injury of other specified intrathoracic organs (with open wound into thoracic cavity)	0.000	0.987	0.013
S27.31 Other injuries of lung (with open wound into thoracic cavity)	0.000	0.987	0.013
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.000	0.988	0.012
M25.7 Osteophyte	0.012	0.988	0.000
M25.74 Osteophyte (Hand)	0.012	0.988	0.000
S27.41 Injury of bronchus (with open wound into thoracic cavity)	0.000	0.988	0.012
S27.40 Injury of bronchus (without open wound into thoracic cavity)	0.000	0.988	0.012
S27.51 Injury of thoracic trachea (with open wound into thoracic cavity)	0.000	0.988	0.012
S27.50 Injury of thoracic trachea (without open wound into thoracic cavity)	0.000	0.988	0.012
S27.61 Injury of pleura (with open wound into thoracic cavity)	0.000	0.988	0.012
S27.60 Injury of pleura (without open wound into thoracic cavity)	0.000	0.988	0.012
S27.71 Multiple injuries of intrathoracic organs (with open wound into thoracic cavity)	0.000	0.988	0.012
S27.70 Multiple injuries of intrathoracic organs (without open wound into thoracic cavity)	0.000	0.988	0.012
S27.91 Injury of unspecified intrathoracic organ (with open wound into thoracic cavity)	0.000	0.988	0.012
S27.90 Injury of unspecified intrathoracic organ (without open wound into thoracic cavity)	0.000	0.988	0.012
S27.11 Traumatic haemothorax (with open wound into thoracic cavity)	0.000	0.988	0.011
S29.7 Multiple injuries of thorax	0.000	0.988	0.011
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.000	0.989	0.011
M25.73 Osteophyte (Forearm)	0.011	0.989	0.000
S06.2 Diffuse brain injury	0.000	0.989	0.011
M25.78 Osteophyte (Other)	0.011	0.989	0.000
S29.8 Other specified injuries of thorax	0.000	0.989	0.011
S29.9 Unspecified injury of thorax	0.000	0.989	0.011
S29.0 Injury of muscle and tendon at thorax level	0.000	0.989	0.010
M25.4 Effusion of joint	0.010	0.990	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.010	0.990	0.000
M25.75 Osteophyte (Pelvic region and thigh)	0.010	0.990	0.000
M25 Other joint disorders, not elsewhere classified	0.010	0.990	0.000
M25.76 Osteophyte (Lower leg)	0.010	0.990	0.000
S26.01 Injury of heart with haemopericardium (with open wound into thoracic cavity)	0.000	0.990	0.009
S26.00 Injury of heart with haemopericardium (without open wound into thoracic cavity)	0.000	0.990	0.009
S26.81 Other injuries of heart (with open wound into thoracic cavity)	0.000	0.990	0.009
S26.80 Other injuries of heart (without open wound into thoracic cavity)	0.000	0.990	0.009
S26.91 Injury of heart, unspecified (with open wound into thoracic cavity)	0.000	0.990	0.009
S26.90 Injury of heart, unspecified (without open wound into thoracic cavity)	0.000	0.990	0.009
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.010	0.990	0.000
S06 Intracranial injury	0.000	0.990	0.010
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.009	0.990	0.000
L57.0 Actinic keratosis	0.000	0.991	0.009
S06.3 Focal brain injury	0.000	0.991	0.009
M77.47 Metatarsalgia-Ankle/Foot	0.000	0.991	0.009
M25.71 Osteophyte (Shoulder region)	0.009	0.991	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.000	0.991	0.009
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.009	0.991	0.000
M25.79 Osteophyte (Site unspecified)	0.009	0.991	0.000
M25.70 Osteophyte (Multiple sites)	0.009	0.991	0.000
M25.3 Other instability of joint	0.009	0.991	0.000
M25.44 Effusion of joint (Hand)	0.008	0.991	0.000
M25.40 Effusion of joint (Multiple sites)	0.008	0.991	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.008	0.991	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.008	0.991	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.000	0.992	0.008
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.008	0.992	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.000	0.992	0.008
S06.5 Traumatic subdural haemorrhage	0.000	0.992	0.008
S06.9 Intracranial injury, unspecified	0.000	0.992	0.008
M25.45 Effusion of joint (Pelvic region and thigh)	0.008	0.992	0.000
S02.10 Fracture of base of skull (closed)	0.000	0.992	0.008
M25.49 Effusion of joint (Site unspecified)	0.008	0.992	0.000
M25.48 Effusion of joint (Other)	0.008	0.992	0.000
M25.34 Other instability of joint (Hand)	0.008	0.992	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.008	0.992	0.000
S42.0 Fracture of clavicle	0.000	0.992	0.008
R40.2 Coma, unspecified	0.007	0.993	0.000
M25.41 Effusion of joint (Shoulder region)	0.007	0.993	0.000
M25.2 Flail joint	0.007	0.993	0.000
M25.1 Fistula of joint	0.007	0.993	0.000
M25.33 Other instability of joint (Forearm)	0.007	0.993	0.000
M25.9 Joint disorder, unspecified	0.007	0.993	0.000
M25.42 Effusion of joint (Upper arm)	0.007	0.993	0.000
S06.8 Other intracranial injuries	0.000	0.993	0.007
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.000	0.993	0.007
M25.0 Haemarthrosis	0.007	0.993	0.000
S06.7 Intracranial injury with prolonged coma	0.000	0.993	0.007
S06.1 Traumatic cerebral oedema	0.000	0.993	0.007
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.000	0.993	0.007
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.000	0.993	0.007
M25.31 Other instability of joint (Shoulder region)	0.007	0.993	0.000
S06.31 Focal brain injury (with open intracranial wound)	0.000	0.993	0.007
M25.36 Other instability of joint (Lower leg)	0.007	0.993	0.000
M25.72 Osteophyte (Upper arm)	0.007	0.993	0.000
M25.39 Other instability of joint (Site unspecified)	0.006	0.993	0.000
M25.38 Other instability of joint (Other)	0.006	0.993	0.000
M25.35 Other instability of joint (Pelvic region and thigh)	0.006	0.993	0.000
M25.32 Other instability of joint (Upper arm)	0.006	0.993	0.000
M25.30 Other instability of joint (Multiple sites)	0.006	0.993	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.006	0.993	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.006	0.993	0.000
C15 Malignant neoplasm of oesophagus	0.000	0.994	0.006
S06.4 Epidural haemorrhage	0.000	0.994	0.006
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.000	0.994	0.006
S62.30 Fracture of other metacarpal bone (closed)	0.000	0.994	0.006
Y57.9 Drug or medicament, unspecified	0.000	0.994	0.006
M25.99 Joint disorder, unspecified (Site unspecified)	0.006	0.994	0.000
C15.3 Upper third of oesophagus	0.000	0.994	0.006
S20 Superficial injury of thorax	0.003	0.994	0.003
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.000	0.994	0.006
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.000	0.994	0.006
C15.9 Oesophagus, unspecified	0.000	0.994	0.006
S06.0 Concussion	0.000	0.994	0.006
C15.5 Lower third of oesophagus	0.000	0.994	0.006
M25.98 Joint disorder, unspecified (Other)	0.006	0.994	0.000
M25.93 Joint disorder, unspecified (Forearm)	0.006	0.994	0.000
S42.01 Fracture of clavicle (open)	0.000	0.994	0.006
M25.92 Joint disorder, unspecified (Upper arm)	0.006	0.994	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.000	0.994	0.006
J99.1 Respiratory disorders in other diffuse connective tissue disorders	0.000	0.994	0.006
M25.19 Fistula of joint (Site unspecified)	0.005	0.994	0.000
M25.18 Fistula of joint (Other)	0.005	0.994	0.000
M25.17 Fistula of joint (Ankle and foot)	0.005	0.994	0.000
M25.16 Fistula of joint (Lower leg)	0.005	0.994	0.000
M25.15 Fistula of joint (Pelvic region and thigh)	0.005	0.994	0.000
M25.14 Fistula of joint (Hand)	0.005	0.994	0.000
M25.13 Fistula of joint (Forearm)	0.005	0.994	0.000
M25.12 Fistula of joint (Upper arm)	0.005	0.994	0.000
M25.11 Fistula of joint (Shoulder region)	0.005	0.994	0.000
M25.10 Fistula of joint (Multiple sites)	0.005	0.994	0.000
M25.29 Flail joint (Site unspecified)	0.005	0.994	0.000
M25.28 Flail joint (Other)	0.005	0.994	0.000
M25.27 Flail joint (Ankle and foot)	0.005	0.994	0.000
M25.26 Flail joint (Lower leg)	0.005	0.994	0.000
M25.25 Flail joint (Pelvic region and thigh)	0.005	0.994	0.000
M25.24 Flail joint (Hand)	0.005	0.994	0.000
M25.23 Flail joint (Forearm)	0.005	0.994	0.000
M25.22 Flail joint (Upper arm)	0.005	0.994	0.000
M25.21 Flail joint (Shoulder region)	0.005	0.994	0.000
M25.20 Flail joint (Multiple sites)	0.005	0.994	0.000
M25.97 Joint disorder, unspecified (Ankle and foot)	0.005	0.994	0.000
M25.90 Joint disorder, unspecified (Multiple sites)	0.005	0.994	0.000
S06.81 Other intracranial injuries (with open intracranial wound)	0.000	0.994	0.005
M25.43 Effusion of joint (Forearm)	0.005	0.995	0.000
S20.8 Superficial injuries of other and unspecified parts of thorax	0.005	0.995	0.000
C15.0 Cervical part of oesophagus	0.000	0.995	0.005
M25.09 Haemarthrosis (Site unspecified)	0.005	0.995	0.000
M25.08 Haemarthrosis (Other)	0.005	0.995	0.000
M25.07 Haemarthrosis (Ankle and foot)	0.005	0.995	0.000
M25.05 Haemarthrosis (Pelvic region and thigh)	0.005	0.995	0.000
M25.04 Haemarthrosis (Hand)	0.005	0.995	0.000
M25.03 Haemarthrosis (Forearm)	0.005	0.995	0.000
M25.02 Haemarthrosis (Upper arm)	0.005	0.995	0.000
M25.01 Haemarthrosis (Shoulder region)	0.005	0.995	0.000
M25.00 Haemarthrosis (Multiple sites)	0.005	0.995	0.000
M25.46 Effusion of joint (Lower leg)	0.005	0.995	0.000
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.000	0.995	0.005
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.000	0.995	0.005
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.000	0.995	0.005
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.000	0.995	0.005
M25.37 Other instability of joint (Ankle and foot)	0.005	0.995	0.000
M25.94 Joint disorder, unspecified (Hand)	0.005	0.995	0.000
M25.96 Joint disorder, unspecified (Lower leg)	0.005	0.995	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.005	0.995	0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.005	0.995	0.000
M25.06 Haemarthrosis (Lower leg)	0.005	0.995	0.000
C15.4 Middle third of oesophagus	0.000	0.995	0.005
C21.1 Anal canal	0.000	0.995	0.005
Q05.9 Spina bifida, unspecified	0.005	0.995	0.000
Y57 Other and unspecified drugs and medicaments	0.000	0.995	0.005
Y57.6 Other diagnostic agents	0.000	0.995	0.005
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.005	0.995	0.000
J95.0 Tracheostomy malfunction	0.000	0.995	0.005
C15.8 Overlapping lesion of oesophagus	0.000	0.995	0.005
C15.2 Abdominal part of oesophagus	0.000	0.995	0.005
C15.1 Thoracic part of oesophagus	0.000	0.995	0.005
S02.1 Fracture of base of skull	0.000	0.995	0.005
S06.41 Epidural haemorrhage (with open intracranial wound)	0.000	0.995	0.005
Y57.8 Other drugs and medicaments	0.000	0.995	0.005
C21 Malignant neoplasm of anus and anal canal	0.000	0.995	0.005
C26.0 Intestinal tract, part unspecified	0.000	0.995	0.005
R40 Somnolence, stupor and coma	0.005	0.995	0.000
S20.7 Multiple superficial injuries of thorax	0.002	0.995	0.002
S06.01 Concussion (with open intracranial wound)	0.000	0.995	0.004
M25.91 Joint disorder, unspecified (Shoulder region)	0.004	0.995	0.000
S20.0 Contusion of breast	0.003	0.995	0.002
O32.1 Maternal care for breech presentation	0.005	0.995	0.000
S20.4 Other superficial injuries of back wall of thorax	0.002	0.996	0.002
R40.1 Stupor	0.004	0.996	0.000
S20.1 Other and unspecified superficial injuries of breast	0.002	0.996	0.002
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.000	0.996	0.004
S20.3 Other superficial injuries of front wall of thorax	0.003	0.996	0.001
C21.8 Overlapping lesion of rectum, anus and anal canal	0.000	0.996	0.004
C21.0 Anus, unspecified	0.000	0.996	0.004
I49.8 Other specified cardiac arrhythmias	0.000	0.996	0.004
M77.4 Metatarsalgia	0.000	0.996	0.004
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.996	0.004
C26 Malignant neoplasm of other and ill-defined digestive organs	0.000	0.996	0.004
T88.4 Failed or difficult intubation	0.000	0.996	0.004
D46.9 Myelodysplastic syndrome, unspecified	0.004	0.996	0.000
T88.5 Other complications of anaesthesia	0.000	0.996	0.004
S62.3 Fracture of other metacarpal bone	0.000	0.996	0.004
T88 Other complications of surgical and medical care, not elsewhere classified	0.000	0.996	0.004
Y57.7 Vitamins, not elsewhere classified	0.000	0.996	0.004
Y57.4 Pharmaceutical excipients	0.000	0.996	0.004
Y57.3 Alcohol deterrents	0.000	0.996	0.004
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.000	0.996	0.004
Y57.1 Lipotropic drugs	0.000	0.996	0.004
Y57.0 Appetite depressants [anorectics]	0.000	0.996	0.004
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.000	0.996	0.004
S06.40 Epidural haemorrhage (without open intracranial wound)	0.000	0.996	0.004
C18.2 Ascending colon	0.000	0.996	0.004
J99 Respiratory disorders in diseases classified elsewhere	0.000	0.996	0.004
C21.2 Cloacogenic zone	0.000	0.996	0.004
S20.2 Contusion of thorax	0.002	0.996	0.002
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.000	0.996	0.004
Q05 Spina bifida	0.004	0.996	0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.000	0.996	0.004
C26.9 Ill-defined sites within the digestive system	0.000	0.996	0.003
M21.0 Valgus deformity, not elsewhere classified	0.003	0.997	0.000
C15-C26 Malignant neoplasms of digestive organs	0.000	0.997	0.003
T88.2 Shock due to anaesthesia	0.000	0.997	0.003
R40.0 Somnolence	0.003	0.997	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.003	0.997	0.000
S06.00 Concussion (without open intracranial wound)	0.000	0.997	0.003
Y57.5 X-ray contrast media	0.000	0.997	0.003
L57 Skin changes due to chronic exposure to nonionising radiation	0.000	0.997	0.003
Z93.0 Tracheostomy status	0.000	0.997	0.003
C17 Malignant neoplasm of small intestine	0.000	0.997	0.003
M77.49 Metatarsalgia-Site unspec	0.000	0.997	0.003
M77.48 Metatarsalgia-Other	0.000	0.997	0.003
M77.46 Metatarsalgia-Lower Leg	0.000	0.997	0.003
M77.45 Metatarsalgia-Pelvic/Thigh	0.000	0.997	0.003
M77.44 Metatarsalgia-Hand	0.000	0.997	0.003
M77.43 Metatarsalgia-Forearm	0.000	0.997	0.003
M77.42 Metatarsalgia-Upper arm	0.000	0.997	0.003
M77.41 Metatarsalgia-Shldr region	0.000	0.997	0.003
M77.40 Metatarsalgia-Mult sites	0.000	0.997	0.003
S02.9 Fracture of skull and facial bones, part unspecified	0.000	0.997	0.003
S02.11 Fracture of base of skull (open)	0.000	0.997	0.003
C17.0 Duodenum	0.000	0.997	0.003
C26.8 Overlapping lesion of digestive system	0.000	0.997	0.003
C26.1 Spleen	0.000	0.997	0.003
Q51.3 Bicornate uterus	0.000	0.997	0.003
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.000	0.997	0.003
J99.0 Rheumatoid lung disease	0.000	0.997	0.003
S62.31 Fracture of other metacarpal bone (open)	0.000	0.997	0.003
Q05.4 Unspecified spina bifida with hydrocephalus	0.003	0.997	0.000
S02 Fracture of skull and facial bones	0.000	0.997	0.003
M89.55 Osteolysis (Pelvic region and thigh)	0.003	0.997	0.000
Q05.7 Lumbar spina bifida without hydrocephalus	0.003	0.997	0.000
T88.3 Malignant hyperthermia due to anaesthesis	0.000	0.997	0.003
T88.1 Other complications following immunisation, not elsewhere classified	0.000	0.997	0.003
T88.0 Infection following immunisation	0.000	0.997	0.003
J99.8 Respiratory disorders in other diseases classified elsewhere	0.000	0.997	0.003
M07.30 Other psoriatic arthropathies (Multiple sites)	0.000	0.997	0.003
D04.5 Skin of trunk	0.003	0.997	0.000
M25.8 Other specified joint disorders	0.003	0.997	0.000
C23 Malignant neoplasm of gallbladder	0.000	0.997	0.003
Q51 Congenital malformations of uterus and cervix	0.000	0.997	0.003
N04.9 Unspecified	0.003	0.997	0.000
Q05.8 Sacral spina bifida without hydrocephalus	0.003	0.997	0.000
Q05.6 Thoracic spina bifida without hydrocephalus	0.003	0.997	0.000
Q05.5 Cervical spina bifida without hydrocephalus	0.003	0.997	0.000
Q05.3 Sacral spina bifida with hydrocephalus	0.003	0.997	0.000
Q05.2 Lumbar spina bifida with hydrocephalus	0.003	0.997	0.000
Q05.1 Thoracic spina bifida with hydrocephalus	0.003	0.997	0.000
Q05.0 Cervical spina bifida with hydrocephalus	0.003	0.997	0.000
S02.8 Fractures of other skull and facial bones	0.000	0.997	0.003
S02.7 Multiple fractures involving skull and facial bones	0.000	0.997	0.003
C17.1 Jejunum	0.000	0.997	0.003
M80.5 Idiopathic osteoporosis with pathological fracture	0.000	0.997	0.003
M70.65 Trochanteric bursitis-Pelvic/Thigh	0.000	0.997	0.003
A41.8 Other specified septicaemia	0.003	0.997	0.000
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified	0.000	0.997	0.003
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.003	0.997	0.000
M21.08 Valgus deformity, not elsewhere classified (Other)	0.003	0.997	0.000
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.003	0.997	0.000
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.003	0.997	0.000
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.003	0.997	0.000
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.003	0.997	0.000
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.003	0.997	0.000
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.003	0.997	0.000
Q52.5 Fusion of labia	0.000	0.997	0.003
M25.77 Osteophyte (Ankle and foot)	0.003	0.997	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.000	0.997	0.003
S02.70 Multiple fractures involving skull and facial bones (closed)	0.000	0.997	0.003
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.000	0.997	0.003
L57.5 Actinic granuloma	0.000	0.997	0.003
L57.3 Poikiloderma of Civatte	0.000	0.997	0.003
L57.2 Cutis rhomboidalis nuchae	0.000	0.997	0.003
L57.1 Actinic reticuloid	0.000	0.997	0.003
S02.80 Fractures of other skull and facial bones (closed)	0.000	0.997	0.003
C18.0 Caecum	0.000	0.997	0.003
C17.8 Overlapping lesion of small intestine	0.000	0.997	0.003
C17.3 Meckel's diverticulum	0.000	0.997	0.003
N28.1 Cyst of kidney, acquired	0.000	0.997	0.003
D46 Myelodysplastic syndromes	0.003	0.997	0.000
D72.8 Other specified disorders of white blood cells	0.003	0.997	0.000
Q54 Hypospadias	0.000	0.997	0.003
Q52 Other congenital malformations of female genitalia	0.000	0.997	0.003
M79.19 Myalgia (Site unspecified)	0.003	0.997	0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.000	0.997	0.002
C17.2 Ileum	0.000	0.997	0.003
Q51.2 Other doubling of uterus	0.000	0.997	0.003
G80.9 Infantile cerebral palsy, unspecified	0.000	0.997	0.003
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.000	0.997	0.002
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.000	0.997	0.002
C17.9 Small intestine, unspecified	0.000	0.997	0.002
T88.7 Unspecified adverse effect of drug or medicament	0.000	0.997	0.003
Q54.1 Hypospadias, penile	0.000	0.997	0.002
T88.9 Complication of surgical and medical care, unspecified	0.000	0.997	0.002
Q54.0 Hypospadias, balanic	0.000	0.997	0.002
C24.9 Biliary tract, unspecified	0.000	0.998	0.002
Q50-Q56 Congenital malformations of genital organs	0.000	0.998	0.002
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.000	0.998	0.002
M25.82 Other specified joint disorders (Upper arm)	0.002	0.998	0.000
M25.83 Other specified joint disorders (Forearm)	0.002	0.998	0.000
S02.3 Fracture of orbital floor	0.000	0.998	0.002
Z93.1 Gastrostomy status	0.000	0.998	0.002
D46.4 Refractory anaemia, unspecified	0.002	0.998	0.000
M35.7 Hypermobility syndrome	0.002	0.998	0.000
C22.0 Liver cell carcinoma	0.000	0.998	0.002
F60.9 Personality disorder, unspecified	0.000	0.998	0.002
M25.89 Other specified joint disorders (Site unspecified)	0.002	0.998	0.000
M25.80 Other specified joint disorders (Multiple sites)	0.002	0.998	0.000
F05.9 Delirium, unspecified	0.000	0.998	0.002
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.000	0.998	0.002
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.000	0.998	0.002
Q51.6 Embryonic cyst of cervix	0.000	0.998	0.002
Q51.5 Agenesis and aplasia of cervix	0.000	0.998	0.002
Q51.4 Unicornate uterus	0.000	0.998	0.002
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.000	0.998	0.002
Q51.0 Agenesis and aplasia of uterus	0.000	0.998	0.002
S02.71 Multiple fractures involving skull and facial bones (open)	0.000	0.998	0.002
D46.7 Other myelodysplastic syndromes	0.002	0.998	0.000
L57.4 Cutis laxa senilis	0.000	0.998	0.002
S02.0 Fracture of vault of skull	0.000	0.998	0.002
S02.81 Fractures of other skull and facial bones (open)	0.000	0.998	0.002
Z43.1 Attention to gastrostomy	0.000	0.998	0.002
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.002
M80.58 Idiopathic osteoporosis with pathological fracture (Other)	0.000	0.998	0.002
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.002
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.002
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.002
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)	0.000	0.998	0.002
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.002
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.002
G80.2 Infantile hemiplegia	0.000	0.998	0.002
G80.1 Spastic diplegia	0.000	0.998	0.002
S02.5 Fracture of tooth	0.000	0.998	0.002
D46.1 Refractory anaemia with sideroblasts	0.002	0.998	0.000
S62.10 Fracture of other carpal bone(s) (closed)	0.000	0.998	0.002
D46.2 Refractory anaemia with excess of blasts	0.002	0.998	0.000
Q52.1 Doubling of vagina	0.000	0.998	0.002
G80 Infantile cerebral palsy	0.000	0.998	0.002
H61.0 Perichondritis of external ear	0.002	0.998	0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung	0.000	0.998	0.002
C22.7 Other specified carcinomas of liver	0.000	0.998	0.002
C22.4 Other sarcomas of liver	0.000	0.998	0.002
C22.3 Angiosarcoma of liver	0.000	0.998	0.002
C22.2 Hepatoblastoma	0.000	0.998	0.002
Q51.8 Other congenital malformations of uterus and cervix	0.000	0.998	0.002
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.002
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.000	0.998	0.002
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.002
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.002
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.002
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.000	0.998	0.002
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.002
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.002
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.002
M25.88 Other specified joint disorders (Other)	0.002	0.998	0.000
Z03.4 Observation for suspected myocardial infarction	0.000	0.998	0.002
C22.9 Liver, unspecified	0.000	0.998	0.002
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.002	0.998	0.000
D46.5 Refractory anaemia with multi-lineage dysplasia	0.002	0.998	0.000
D46.3 Refractory anaemia with excess of blasts with transformation	0.002	0.998	0.000
D46.0 Refractory anaemia without sideroblasts, so stated	0.002	0.998	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.002	0.998	0.000
Q54.8 Other hypospadias	0.000	0.998	0.002
Q54.4 Congenital chordee	0.000	0.998	0.002
Q54.3 Hypospadias, perineal	0.000	0.998	0.002
Q54.2 Hypospadias, penoscrotal	0.000	0.998	0.002
S02.4 Fracture of malar and maxillary bones	0.000	0.998	0.002
I22 Subsequent myocardial infarction	0.000	0.998	0.002
Q55 Other congenital malformations of male genital organs	0.000	0.998	0.002
M79.1 Myalgia	0.002	0.998	0.000
Q52.9 Congenital malformation of female genitalia, unspecified	0.000	0.998	0.002
Q52.8 Other specified congenital malformations of female genitalia	0.000	0.998	0.002
Q52.7 Other congenital malformations of vulva	0.000	0.998	0.002
Q52.6 Congenital malformation of clitoris	0.000	0.998	0.002
Q52.4 Other congenital malformations of vagina	0.000	0.998	0.002
Q52.3 Imperforate hymen	0.000	0.998	0.002
Q52.2 Congenital rectovaginal fistula	0.000	0.998	0.002
Q52.0 Congenital absence of vagina	0.000	0.998	0.002
S62.1 Fracture of other carpal bone(s)	0.000	0.998	0.002
Z93.3 Colostomy status	0.000	0.998	0.002
J95 Postprocedural respiratory disorders, not elsewhere classified	0.000	0.998	0.002
C24.8 Overlapping lesion of biliary tract	0.000	0.998	0.002
H60.1 Cellulitis of external ear	0.002	0.998	0.000
Q54.9 Hypospadias, unspecified	0.000	0.998	0.002
S02.6 Fracture of mandible	0.000	0.998	0.002
C24.0 Extrahepatic bile duct	0.000	0.998	0.002
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.998	0.002
S62 Fracture at wrist and hand level	0.000	0.998	0.002
V89.2 Person injured in unspecified motor-vehicle accident, traffic	0.002	0.998	0.000
M25.87 Other specified joint disorders (Ankle and foot)	0.002	0.998	0.000
M79.18 Myalgia (Other)	0.002	0.998	0.000
M79.10 Myalgia (Multiple sites)	0.002	0.998	0.000
Q53 Undescended testicle	0.000	0.998	0.002
M25.84 Other specified joint disorders (Hand)	0.002	0.998	0.000
I07.1 Tricuspid insufficiency	0.000	0.998	0.002
N04.2 Diffuse membranous glomerulonephritis	0.002	0.998	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.000	0.998	0.002
M25.81 Other specified joint disorders (Shoulder region)	0.002	0.998	0.000
N18.3 Chronic kidney disease, stage 3	0.000	0.998	0.002
N04 Nephrotic syndrome	0.002	0.998	0.000
M79.11 Myalgia (Shoulder region)	0.002	0.998	0.000
M79.16 Myalgia (Lower leg)	0.002	0.998	0.000
S02.31 Fracture of orbital floor (open)	0.000	0.998	0.002
S62.51 Fracture of thumb (open)	0.000	0.998	0.002
I49.1 Atrial premature depolarisation	0.000	0.998	0.002
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.002	0.998	0.000
S32.40 Fracture of acetabulum (closed)	0.000	0.998	0.002
D68.8 Other specified coagulation defects	0.000	0.998	0.002
G80.0 Spastic cerebral palsy	0.000	0.998	0.002
Q55.6 Other congenital malformations of penis	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations