TreeWAS – Variant ID: rs683250

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
N18.9 Chronic renal failure, unspecified	0.000	0.709	0.291
N18 Chronic renal failure	0.000	0.710	0.290
N18.0 End-stage renal disease	0.000	0.719	0.281
N18.8 Other chronic renal failure	0.000	0.738	0.262
N18.4 Chronic kidney disease, stage 4	0.000	0.738	0.262
N18.5 Chronic kidney disease, stage 5	0.000	0.747	0.253
N18.1 Chronic kidney disease, stage 1	0.000	0.747	0.253
N18.2 Chronic kidney disease, stage 2	0.000	0.819	0.181
C67 Malignant neoplasm of bladder	0.000	0.902	0.098
C67.2 Lateral wall of bladder	0.000	0.903	0.097
C67.9 Bladder, unspecified	0.000	0.904	0.096
C67.1 Dome of bladder	0.000	0.905	0.095
C67.3 Anterior wall of bladder	0.000	0.920	0.080
C67.7 Urachus	0.000	0.930	0.070
C67.5 Bladder neck	0.000	0.931	0.069
N17-N19 Renal failure	0.000	0.933	0.067
C67.0 Trigone of bladder	0.000	0.934	0.066
C67.6 Ureteric orifice	0.000	0.938	0.062
C67.4 Posterior wall of bladder	0.000	0.938	0.062
N18.3 Chronic kidney disease, stage 3	0.000	0.938	0.062
C67.8 Overlapping lesion of bladder	0.000	0.941	0.059
C64-C68 Malignant neoplasms of urinary tract	0.000	0.949	0.051
J35.0 Chronic tonsillitis	0.000	0.958	0.042
C64 Malignant neoplasm of kidney, except renal pelvis	0.000	0.960	0.040
N17 Acute renal failure	0.000	0.960	0.040
K70 Alcoholic liver disease	0.000	0.961	0.039
K70.3 Alcoholic cirrhosis of liver	0.000	0.962	0.038
C65 Malignant neoplasm of renal pelvis	0.000	0.962	0.038
C68 Malignant neoplasm of other and unspecified urinary organs	0.000	0.962	0.038
Z99.1 Dependence on respirator	0.000	0.963	0.037
K70.9 Alcoholic liver disease, unspecified	0.000	0.963	0.037
C66 Malignant neoplasm of ureter	0.000	0.965	0.035
N19 Unspecified renal failure	0.000	0.965	0.035
K70.2 Alcoholic fibrosis and sclerosis of liver	0.000	0.965	0.035
K70.1 Alcoholic hepatitis	0.000	0.966	0.034
N17.8 Other acute renal failure	0.000	0.967	0.033
K70.0 Alcoholic fatty liver	0.000	0.967	0.033
K70.4 Alcoholic hepatic failure	0.000	0.969	0.031
N17.2 Acute renal failure with medullary necrosis	0.000	0.971	0.029
N17.1 Acute renal failure with acute cortical necrosis	0.000	0.971	0.029
C68.0 Urethra	0.000	0.971	0.029
C68.8 Overlapping lesion of urinary organs	0.000	0.973	0.027
C68.1 Paraurethral glands	0.000	0.973	0.027
C68.9 Urinary organ, unspecified	0.000	0.973	0.027
N17.0 Acute renal failure with tubular necrosis	0.000	0.974	0.026
I67.1 Cerebral aneurysm, nonruptured	0.000	0.981	0.019
K04.9 Other and unspecified diseases of pulp and periapical tissues	0.000	0.984	0.016
N17.9 Acute renal failure, unspecified	0.000	0.985	0.015
H00.0 Hordeolum and other deep inflammation of eyelid	0.000	0.988	0.012
T42.4 Benzodiazepines	0.000	0.988	0.012
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.988	0.012
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.989	0.011
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.991	0.009
R18 Ascites	0.000	0.991	0.009
T42.1 Iminostilbenes	0.000	0.991	0.009
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.992	0.008
T42.2 Succinimides and oxazolidinediones	0.000	0.992	0.008
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.992	0.008
T39.1 4-Aminophenol derivatives	0.000	0.992	0.008
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.992	0.008
T42.3 Barbiturates	0.000	0.992	0.008
T42.0 Hydantoin derivatives	0.000	0.992	0.008
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.992	0.008
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.993	0.007
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.993	0.007
T39.0 Salicylates	0.000	0.993	0.007
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.000	0.993	0.007
Z99.2 Dependence on renal dialysis	0.000	0.994	0.006
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.994	0.006
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.994	0.006
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.994	0.006
T46.1 Calcium-channel blockers	0.000	0.994	0.006
T36 Poisoning by systemic antibiotics	0.000	0.994	0.006
T39.4 Antirheumatics, not elsewhere classified	0.000	0.994	0.006
T39.2 Pyrazolone derivatives	0.000	0.994	0.006
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.994	0.006
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.994	0.006
E27.2 Addisonian crisis	0.000	0.994	0.006
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.994	0.006
J35 Chronic diseases of tonsils and adenoids	0.000	0.994	0.006
E27 Other disorders of adrenal gland	0.000	0.994	0.006
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.994	0.006
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.994	0.006
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.994	0.006
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.994	0.006
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.994	0.005
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.994	0.005
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.994	0.005
T46.7 Peripheral vasodilators	0.000	0.994	0.005
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.994	0.005
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.994	0.005
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.995	0.005
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.995	0.005
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.995	0.005
N31.8 Other neuromuscular dysfunction of bladder	0.000	0.995	0.005
E27.9 Disorder of adrenal gland, unspecified	0.000	0.995	0.005
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.995	0.005
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.995	0.005
Z99.4 Dependence on artificial heart	0.000	0.995	0.005
Z99.0 Dependence on aspirator	0.000	0.995	0.005
T40.4 Other synthetic narcotics	0.000	0.995	0.005
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.995	0.005
N83.0 Follicular cyst of ovary	0.000	0.995	0.005
T36.0 Penicillins	0.000	0.995	0.005
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.995	0.005
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.995	0.005
S64.4 Injury of digital nerve of other finger	0.000	0.995	0.005
Z99.9 Dependence on unspecified enabling machine and device	0.000	0.995	0.005
T40.6 Other and unspecified narcotics	0.000	0.995	0.005
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.005	0.995	0.000
K05.6 Periodontal disease, unspecified	0.005	0.995	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.995	0.005
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.995	0.005
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.995	0.005
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.995	0.005
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.995	0.005
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.995	0.005
T44.0 Anticholinesterase agents	0.000	0.995	0.005
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.995	0.005
T48.5 Anti-common-cold drugs	0.000	0.995	0.005
T48.4 Expectorants	0.000	0.995	0.005
T48.3 Antitussives	0.000	0.995	0.005
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.995	0.005
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.995	0.005
T48.0 Oxytocic drugs	0.000	0.995	0.005
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.995	0.005
T36.9 Systemic antibiotic, unspecified	0.000	0.995	0.004
T36.8 Other systemic antibiotics	0.000	0.995	0.004
T36.7 Antifungal antibiotics, systemically used	0.000	0.995	0.004
T36.6 Rifamycins	0.000	0.995	0.004
T36.5 Aminoglycosides	0.000	0.995	0.004
T36.3 Macrolides	0.000	0.995	0.004
T36.2 Chloramphenicol group	0.000	0.995	0.004
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.995	0.004
W10.8 Other specified place	0.005	0.995	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.995	0.005
T38.1 Thyroid hormones and substitutes	0.000	0.995	0.004
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.995	0.005
T41.5 Therapeutic gases	0.000	0.995	0.004
T41.4 Anaesthetic, unspecified	0.000	0.995	0.004
T41.3 Local anaesthetics	0.000	0.995	0.004
T41.2 Other and unspecified general anaesthetics	0.000	0.995	0.004
T41.1 Intravenous anaesthetics	0.000	0.995	0.004
T41.0 Inhaled anaesthetics	0.000	0.995	0.004
D75.8 Other specified diseases of blood and blood-forming organs	0.000	0.995	0.005
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.995	0.004
T40.5 Cocaine	0.000	0.995	0.004
J35.3 Hypertrophy of tonsils with hypertrophy of adenoids	0.000	0.996	0.004
E27.5 Adrenomedullary hyperfunction	0.000	0.996	0.004
E27.0 Other adrenocortical overactivity	0.000	0.996	0.004
T38.9 Other and unspecified hormone antagonists	0.000	0.996	0.004
T38.7 Androgens and anabolic congeners	0.000	0.996	0.004
T38.5 Other oestrogens and progestogens	0.000	0.996	0.004
T38.4 Oral contraceptives	0.000	0.996	0.004
T38.2 Antithyroid drugs	0.000	0.996	0.004
T38.0 Glucocorticoids and synthetic analogues	0.000	0.996	0.004
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.996	0.004
T36.4 Tetracyclines	0.000	0.996	0.004
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.996	0.004
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.996	0.004
T40.8 Lysergide [LSD]	0.000	0.996	0.004
T40.7 Cannabis (derivatives)	0.000	0.996	0.004
T40.3 Methadone	0.000	0.996	0.004
T40.0 Opium	0.000	0.996	0.004
T50.7 Analeptics and opioid receptor antagonists	0.000	0.996	0.004
T50.5 Appetite depressants	0.000	0.996	0.004
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.996	0.004
T50.1 Loop [high-ceiling] diuretics	0.000	0.996	0.004
T50.0 Mineralocorticoids and their antagonists	0.000	0.996	0.004
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.996	0.004
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.996	0.004
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.996	0.004
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.996	0.004
T49.9 Topical agent, unspecified	0.000	0.996	0.004
T49.8 Other topical agents	0.000	0.996	0.004
T49.7 Dental drugs, topically applied	0.000	0.996	0.004
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.996	0.004
T49.5 Ophthalmological drugs and preparations	0.000	0.996	0.004
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.996	0.004
T49.3 Emollients, demulcents and protectants	0.000	0.996	0.004
T49.2 Local astringents and local detergents	0.000	0.996	0.004
T49.1 Antipruritics	0.000	0.996	0.004
E27.8 Other specified disorders of adrenal gland	0.000	0.996	0.004
J35.2 Hypertrophy of adenoids	0.000	0.996	0.004
T40.1 Heroin	0.000	0.996	0.004
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.996	0.004
T37.5 Antiviral drugs	0.000	0.996	0.004
T37.4 Anthelminthics	0.000	0.996	0.004
T37.3 Other antiprotozoal drugs	0.000	0.996	0.004
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.996	0.004
T37.1 Antimycobacterial drugs	0.000	0.996	0.004
T37.0 Sulphonamides	0.000	0.996	0.004
T50.4 Drugs affecting uric acid metabolism	0.000	0.996	0.004
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.996	0.004
T43.6 Psychostimulants with abuse potential	0.000	0.996	0.004
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.996	0.004
S22.00 Fracture of thoracic vertebra (closed)	0.000	0.996	0.004
T47.2 Stimulant laxatives	0.000	0.996	0.004
T43.9 Psychotropic drug, unspecified	0.000	0.996	0.004
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.996	0.004
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.996	0.004
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.996	0.004
T47.7 Emetics	0.000	0.996	0.004
T47.6 Antidiarrhoeal drugs	0.000	0.996	0.004
T47.5 Digestants	0.000	0.996	0.004
T47.4 Other laxatives	0.000	0.996	0.004
T47.3 Saline and osmotic laxatives	0.000	0.996	0.004
E27.1 Primary adrenocortical insufficiency	0.000	0.996	0.004
J35.1 Hypertrophy of tonsils	0.000	0.996	0.004
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.996	0.003
T50.8 Diagnostic agents	0.000	0.996	0.004
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.996	0.004
I82.8 Embolism and thrombosis of other specified veins	0.000	0.996	0.004
I85.9 Oesophageal varices without bleeding	0.000	0.996	0.004
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.996	0.004
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.996	0.003
R23.8 Other and unspecified skin changes	0.000	0.996	0.003
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.996	0.003
T45.0 Antiallergic and antiemetic drugs	0.000	0.996	0.003
Z49.1 Extracorporeal dialysis	0.000	0.997	0.003
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.997	0.003
T47.0 Histamine H(2)-receptor antagonists	0.000	0.997	0.003
J35.9 Chronic disease of tonsils and adenoids, unspecified	0.000	0.997	0.003
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.003	0.997	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.997	0.003
T45.8 Other primarily systemic and haematological agents	0.000	0.997	0.003
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.997	0.003
T45.6 Fibrinolysis-affecting drugs	0.000	0.997	0.003
T45.4 Iron and its compounds	0.000	0.997	0.003
T45.3 Enzymes, not elsewhere classified	0.000	0.997	0.003
M47.99 Spondylosis, unspecified (Site unspecified)	0.000	0.997	0.003
K08.3 Retained dental root	0.000	0.997	0.003
M85.8 Other specified disorders of bone density and structure	0.003	0.997	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.997	0.003
Z99.8 Dependence on other enabling machines and devices	0.000	0.997	0.003
M85.88 Other specified disorders of bone density and structure (Other)	0.003	0.997	0.000
Z49.0 Preparatory care for dialysis	0.000	0.997	0.003
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.003	0.997	0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.003	0.997	0.000
Y42.7 Androgens and anabolic congeners	0.000	0.997	0.003
H52.2 Astigmatism	0.003	0.997	0.000
K08.9 Disorder of teeth and supporting structures, unspecified	0.000	0.997	0.003
O44.1 Placenta praevia with haemorrhage	0.000	0.997	0.003
J35.8 Other chronic diseases of tonsils and adenoids	0.000	0.997	0.003
H54.7 Unspecified visual loss	0.003	0.997	0.000
S93.1 Dislocation of toe(s)	0.003	0.997	0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.003	0.997	0.000
T45.2 Vitamins, not elsewhere classified	0.000	0.997	0.002
H54.5 Low vision, one eye	0.003	0.997	0.000
O03.9 Complete or unspecified, without complication	0.000	0.997	0.003
Z49 Care involving dialysis	0.000	0.997	0.003
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.003	0.997	0.000
Z94.8 Other transplanted organ and tissue status	0.003	0.997	0.000
I73.9 Peripheral vascular disease, unspecified	0.000	0.997	0.003
M85.84 Other specified disorders of bone density and structure (Hand)	0.002	0.997	0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.002	0.997	0.000
C15.5 Lower third of oesophagus	0.003	0.997	0.000
K76.8 Other specified diseases of liver	0.003	0.997	0.000
M85.83 Other specified disorders of bone density and structure (Forearm)	0.002	0.998	0.000
T45.5 Anticoagulants	0.000	0.998	0.002
M23.49 Loose body in knee-Unspec lig/men	0.000	0.998	0.002
H00 Hordeolum and chalazion	0.000	0.998	0.002
M85.65 Other cyst of bone (Pelvic region and thigh)	0.002	0.998	0.000
I51.7 Cardiomegaly	0.000	0.998	0.002
K74.0 Hepatic fibrosis	0.000	0.998	0.002
F60.3 Emotionally unstable personality disorder	0.000	0.998	0.002
H54 Blindness and low vision	0.002	0.998	0.000
K08 Other disorders of teeth and supporting structures	0.000	0.998	0.002
Z49.2 Other dialysis	0.000	0.998	0.002
H54.0 Blindness, both eyes	0.002	0.998	0.000
D59.1 Other autoimmune haemolytic anaemias	0.000	0.998	0.002
S22.0 Fracture of thoracic vertebra	0.000	0.998	0.002
H50.5 Heterophoria	0.002	0.998	0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.000	0.998	0.002
E34.0 Carcinoid syndrome	0.000	0.998	0.002
H54.1 Blindness, one eye, low vision, other eye	0.002	0.998	0.000
M85 Other disorders of bone density and structure	0.002	0.998	0.000
M85.6 Other cyst of bone	0.002	0.998	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.000	0.998	0.002
R23.0 Cyanosis	0.000	0.998	0.002
M85.66 Other cyst of bone (Lower leg)	0.002	0.998	0.000
H54.6 Unqualified visual loss, one eye	0.002	0.998	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.000	0.998	0.002
J15.7 Pneumonia due to Mycoplasma pneumoniae	0.000	0.998	0.002
D59.9 Acquired haemolytic anaemia, unspecified	0.000	0.998	0.002
H40.0 Glaucoma suspect	0.002	0.998	0.000
I84.3 External thrombosed haemorrhoids	0.000	0.998	0.002
Z91.6 Personal history of other physical trauma	0.002	0.998	0.000
I51.6 Cardiovascular disease, unspecified	0.000	0.998	0.002
I98 Other disorders of circulatory system in diseases classified elsewhere	0.000	0.998	0.002
K70-K77 Diseases of liver	0.000	0.998	0.002
D23.9 Skin, unspecified	0.000	0.998	0.002
M85.0 Fibrous dysplasia (monostotic)	0.002	0.998	0.000
K08.0 Exfoliation of teeth due to systemic causes	0.000	0.998	0.002
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.002	0.998	0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.002	0.998	0.000
H54.3 Unqualified visual loss, both eyes	0.002	0.998	0.000
K74 Fibrosis and cirrhosis of liver	0.000	0.998	0.002
M85.4 Solitary bone cyst	0.002	0.998	0.000
S22.01 Fracture of thoracic vertebra (open)	0.000	0.998	0.002
D59 Acquired haemolytic anaemia	0.000	0.998	0.002
I84.4 External haemorrhoids with other complications	0.000	0.998	0.002
R86.8 Other abnormal findings	0.000	0.998	0.002
S64 Injury of nerves at wrist and hand level	0.000	0.998	0.002
M85.5 Aneurysmal bone cyst	0.002	0.998	0.000
M85.3 Osteitis condensans	0.002	0.998	0.000
M85.1 Skeletal fluorosis	0.002	0.998	0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.000	0.998	0.002
M85.69 Other cyst of bone (Site unspecified)	0.002	0.998	0.000
M85.63 Other cyst of bone (Forearm)	0.002	0.998	0.000
M85.62 Other cyst of bone (Upper arm)	0.002	0.998	0.000
M85.61 Other cyst of bone (Shoulder region)	0.002	0.998	0.000
M85.60 Other cyst of bone (Multiple sites)	0.002	0.998	0.000
G93.4 Encephalopathy, unspecified	0.000	0.998	0.002
K08.2 Atrophy of edentulous alveolar ridge	0.000	0.998	0.002
M85.2 Hyperostosis of skull	0.002	0.998	0.000
E34 Other endocrine disorders	0.000	0.998	0.002
I82 Other venous embolism and thrombosis	0.000	0.998	0.002
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.002	0.998	0.000
S64.1 Injury of median nerve at wrist and hand level	0.000	0.998	0.002
R23 Other skin changes	0.000	0.998	0.002
S64.2 Injury of radial nerve at wrist and hand level	0.000	0.998	0.002
L70.0 Acne vulgaris	0.000	0.998	0.002
L92.8 Other granulomatous disorders of skin and subcutaneous tissue	0.000	0.998	0.002
I51 Complications and ill-defined descriptions of heart disease	0.000	0.998	0.002
K12.3 Oral mucositis (ulcerative)	0.000	0.998	0.002
M85.9 Disorder of bone density and structure, unspecified	0.002	0.998	0.000
V89.2 Person injured in unspecified motor-vehicle accident, traffic	0.000	0.998	0.002
I51.8 Other ill-defined heart diseases	0.000	0.998	0.002
I95.9 Hypotension, unspecified	0.000	0.998	0.002
I99 Other and unspecified disorders of circulatory system	0.000	0.998	0.002
I82.3 Embolism and thrombosis of renal vein	0.000	0.998	0.002
I84.7 Unspecified thrombosed haemorrhoids	0.002	0.998	0.000
I88.9 Nonspecific lymphadenitis, unspecified	0.002	0.998	0.000
T43.2 Other and unspecified antidepressants	0.000	0.998	0.002
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue	0.000	0.998	0.002
Z84.1 Family history of disorders of the kidney and ureter	0.002	0.998	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.000	0.998	0.002
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
I98.0 Cardiovascular syphilis	0.000	0.998	0.002
K76.6 Portal hypertension	0.000	0.998	0.002
R29.6 Tendency to fall, not elsewhere classified	0.000	0.998	0.002
K77 Liver disorders in diseases classified elsewhere	0.000	0.998	0.002
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)	0.001	0.998	0.000
M85.08 Fibrous dysplasia (monostotic) (Other)	0.001	0.998	0.000
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)	0.001	0.998	0.000
M85.06 Fibrous dysplasia (monostotic) (Lower leg)	0.001	0.998	0.000
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)	0.001	0.998	0.000
M85.04 Fibrous dysplasia (monostotic) (Hand)	0.001	0.998	0.000
M85.03 Fibrous dysplasia (monostotic) (Forearm)	0.001	0.998	0.000
M85.02 Fibrous dysplasia (monostotic) (Upper arm)	0.001	0.998	0.000
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)	0.001	0.998	0.000
H50.0 Convergent concomitant strabismus	0.002	0.998	0.000
H54.2 Low vision, both eyes	0.001	0.998	0.000
Z82.3 Family history of stroke	0.000	0.998	0.002
S22.30 Fracture of rib (closed)	0.000	0.998	0.002
R52.9 Pain, unspecified	0.000	0.998	0.002
M85.47 Solitary bone cyst (Ankle and foot)	0.001	0.998	0.000
M85.45 Solitary bone cyst (Pelvic region and thigh)	0.001	0.998	0.000
K71 Toxic liver disease	0.000	0.998	0.002
M85.49 Solitary bone cyst (Site unspecified)	0.001	0.998	0.000
M85.48 Solitary bone cyst (Other)	0.001	0.998	0.000
M85.46 Solitary bone cyst (Lower leg)	0.001	0.998	0.000
M85.44 Solitary bone cyst (Hand)	0.001	0.998	0.000
M85.43 Solitary bone cyst (Forearm)	0.001	0.998	0.000
M85.42 Solitary bone cyst (Upper arm)	0.001	0.998	0.000
M85.41 Solitary bone cyst (Shoulder region)	0.001	0.998	0.000
M85.40 Solitary bone cyst (Multiple sites)	0.001	0.998	0.000
M85.64 Other cyst of bone (Hand)	0.001	0.998	0.000
D68.6 Other Thrombophilia	0.002	0.998	0.000
I51.5 Myocardial degeneration	0.000	0.998	0.002
K74.4 Secondary biliary cirrhosis	0.000	0.998	0.001
K74.2 Hepatic fibrosis with hepatic sclerosis	0.000	0.998	0.001
K74.1 Hepatic sclerosis	0.000	0.998	0.001
R23.2 Flushing	0.000	0.998	0.002
M85.68 Other cyst of bone (Other)	0.001	0.998	0.000
D59.8 Other acquired haemolytic anaemias	0.000	0.998	0.001
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.000	0.998	0.001
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.000	0.998	0.001
D59.4 Other nonautoimmune haemolytic anaemias	0.000	0.998	0.001
D59.3 Haemolytic-uraemic syndrome	0.000	0.998	0.001
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.000	0.998	0.001
D59.0 Drug-induced autoimmune haemolytic anaemia	0.000	0.998	0.001
H50.1 Divergent concomitant strabismus	0.002	0.998	0.000
M85.67 Other cyst of bone (Ankle and foot)	0.001	0.998	0.000
I51.4 Myocarditis, unspecified	0.000	0.998	0.002
S64.9 Injury of unspecified nerve at wrist and hand level	0.000	0.998	0.001
S64.8 Injury of other nerves at wrist and hand level	0.000	0.998	0.001
M85.19 Skeletal fluorosis (Site unspecified)	0.001	0.998	0.000
M85.18 Skeletal fluorosis (Other)	0.001	0.998	0.000
M85.17 Skeletal fluorosis (Ankle and foot)	0.001	0.998	0.000
M85.16 Skeletal fluorosis (Lower leg)	0.001	0.998	0.000
M85.15 Skeletal fluorosis (Pelvic region and thigh)	0.001	0.998	0.000
M85.14 Skeletal fluorosis (Hand)	0.001	0.998	0.000
M85.13 Skeletal fluorosis (Forearm)	0.001	0.998	0.000
M85.12 Skeletal fluorosis (Upper arm)	0.001	0.998	0.000
M85.11 Skeletal fluorosis (Shoulder region)	0.001	0.998	0.000
M85.10 Skeletal fluorosis (Multiple sites)	0.001	0.998	0.000
M85.39 Osteitis condensans (Site unspecified)	0.001	0.998	0.000
M85.38 Osteitis condensans (Other)	0.001	0.998	0.000
M85.37 Osteitis condensans (Ankle and foot)	0.001	0.998	0.000
M85.36 Osteitis condensans (Lower leg)	0.001	0.998	0.000
M85.35 Osteitis condensans (Pelvic region and thigh)	0.001	0.998	0.000
M85.34 Osteitis condensans (Hand)	0.001	0.998	0.000
M85.33 Osteitis condensans (Forearm)	0.001	0.998	0.000
M85.32 Osteitis condensans (Upper arm)	0.001	0.998	0.000
M85.31 Osteitis condensans (Shoulder region)	0.001	0.998	0.000
M85.30 Osteitis condensans (Multiple sites)	0.001	0.998	0.000
M85.59 Aneurysmal bone cyst (Site unspecified)	0.001	0.998	0.000
M85.58 Aneurysmal bone cyst (Other)	0.001	0.998	0.000
M85.57 Aneurysmal bone cyst (Ankle and foot)	0.001	0.998	0.000
M85.56 Aneurysmal bone cyst (Lower leg)	0.001	0.998	0.000
M85.55 Aneurysmal bone cyst (Pelvic region and thigh)	0.001	0.998	0.000
M85.54 Aneurysmal bone cyst (Hand)	0.001	0.998	0.000
M85.53 Aneurysmal bone cyst (Forearm)	0.001	0.998	0.000
M85.52 Aneurysmal bone cyst (Upper arm)	0.001	0.998	0.000
M85.51 Aneurysmal bone cyst (Shoulder region)	0.001	0.998	0.000
M85.50 Aneurysmal bone cyst (Multiple sites)	0.001	0.998	0.000
H54.4 Blindness, one eye	0.002	0.998	0.000
I82.0 Budd-Chiari syndrome	0.000	0.998	0.001
T40.2 Other opioids	0.000	0.998	0.002
M85.29 Hyperostosis of skull-Site unspec	0.001	0.998	0.000
M85.28 Hyperostosis of skull-Other	0.001	0.998	0.000
M85.27 Hyperostosis of skull-Ankle/Foot	0.001	0.998	0.000
M85.26 Hyperostosis of skull-Lower Leg	0.001	0.998	0.000
M85.25 Hyperostosis of skull-Pelvic/Thigh	0.001	0.998	0.000
M85.24 Hyperostosis of skull-Hand	0.001	0.998	0.000
M85.23 Hyperostosis of skull-Forearm	0.001	0.998	0.000
M85.22 Hyperostosis of skull-Upper arm	0.001	0.998	0.000
M85.21 Hyperostosis of skull-Shldr region	0.001	0.998	0.000
E34.8 Other specified endocrine disorders	0.000	0.998	0.001
E34.5 Androgen resistance syndrome	0.000	0.998	0.001
E34.4 Constitutional tall stature	0.000	0.998	0.001
E34.3 Short stature, not elsewhere classified	0.000	0.998	0.001
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.998	0.001
E34.1 Other hypersecretion of intestinal hormones	0.000	0.998	0.001
I82.1 Thrombophlebitis migrans	0.000	0.998	0.001
K74.6 Other and unspecified cirrhosis of liver	0.000	0.998	0.002
O87.2 Haemorrhoids in the puerperium	0.000	0.998	0.001
S72.20 Subtrochanteric fracture (closed)	0.000	0.998	0.002
E34.9 Endocrine disorder, unspecified	0.000	0.998	0.001
R52.0 Acute pain	0.000	0.998	0.002
S93.0 Dislocation of ankle joint	0.001	0.998	0.000
M85.98 Disorder of bone density and structure, unspecified (Other)	0.001	0.998	0.000
M85.97 Disorder of bone density and structure, unspecified (Ankle and foot)	0.001	0.998	0.000
M85.96 Disorder of bone density and structure, unspecified (Lower leg)	0.001	0.998	0.000
M85.95 Disorder of bone density and structure, unspecified (Pelvic region and thigh)	0.001	0.998	0.000
M85.94 Disorder of bone density and structure, unspecified (Hand)	0.001	0.998	0.000
M85.93 Disorder of bone density and structure, unspecified (Forearm)	0.001	0.998	0.000
M85.92 Disorder of bone density and structure, unspecified (Upper arm)	0.001	0.998	0.000
M85.91 Disorder of bone density and structure, unspecified (Shoulder region)	0.001	0.998	0.000
M85.90 Disorder of bone density and structure, unspecified (Multiple sites)	0.001	0.998	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.000	0.998	0.001
K08.8 Other specified disorders of teeth and supporting structures	0.000	0.998	0.002
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.000	0.998	0.001
K71.1 Toxic liver disease with hepatic necrosis	0.000	0.998	0.001
H50 Other strabismus	0.002	0.998	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.002	0.998	0.000
M85.20 Hyperostosis of skull-Mult sites	0.001	0.998	0.000
R23.1 Pallor	0.000	0.998	0.001
W10 Fall on and from stairs and steps	0.001	0.998	0.000
E28.2 Polycystic ovarian syndrome	0.000	0.998	0.001
F01.9 Vascular dementia, unspecified	0.001	0.998	0.000
L92 Granulomatous disorders of skin and subcutaneous tissue	0.000	0.998	0.001
E20.9 Hypoparathyroidism, unspecified	0.000	0.999	0.001
K77.8 Liver disorders in other diseases classified elsewhere	0.000	0.999	0.001
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.000	0.999	0.001
N28.8 Other specified disorders of kidney and ureter	0.001	0.999	0.000
N92.1 Excessive and frequent menstruation with irregular cycle	0.000	0.999	0.001
M96.0 Pseudarthrosis after fusion or arthrodesis	0.000	0.999	0.001
Y77.3 Surgical instruments, materials and devices (including sutures)	0.001	0.999	0.000
I85 Oesophageal varices	0.000	0.999	0.001
K71.9 Toxic liver disease, unspecified	0.000	0.999	0.001
K71.8 Toxic liver disease with other disorders of liver	0.000	0.999	0.001
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.000	0.999	0.001
K71.5 Toxic liver disease with chronic active hepatitis	0.000	0.999	0.001
K71.4 Toxic liver disease with chronic lobular hepatitis	0.000	0.999	0.001
K71.3 Toxic liver disease with chronic persistent hepatitis	0.000	0.999	0.001
K71.2 Toxic liver disease with acute hepatitis	0.000	0.999	0.001
K80.8 Other cholelithiasis	0.000	0.999	0.001
K86.3 Pseudocyst of pancreas	0.001	0.999	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.000	0.999	0.001
I82.2 Embolism and thrombosis of vena cava	0.000	0.999	0.001
L92.2 Granuloma faciale [eosinophilic granuloma of skin]	0.000	0.999	0.001
N73.9 Female pelvic inflammatory disease, unspecified	0.000	0.999	0.001
E20-E35 Disorders of other endocrine glands	0.000	0.999	0.001
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)	0.001	0.999	0.000
H50.6 Mechanical strabismus	0.001	0.999	0.000
I97.1 Other functional disturbances following cardiac surgery	0.000	0.999	0.001
S64.7 Injury of multiple nerves at wrist and hand level	0.000	0.999	0.001
O44 Placenta praevia	0.000	0.999	0.001
K35.1 Acute appendicitis with peritoneal abscess	0.001	0.999	0.000
E20 Hypoparathyroidism	0.000	0.999	0.001
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.000	0.999	0.001
C34.9 Bronchus or lung, unspecified	0.000	0.999	0.001
C44.3 Skin of other and unspecified parts of face	0.001	0.999	0.000
H40.2 Primary angle-closure glaucoma	0.001	0.999	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.000	0.999	0.001
K74.5 Biliary cirrhosis, unspecified	0.000	0.999	0.001
H52 Disorders of refraction and accommodation	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations