TreeWAS – Variant ID: rs6888304

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T43.0 Tricyclic and tetracyclic antidepressants	0.023	0.977	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.023	0.977	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.022	0.978	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.022	0.978	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.022	0.978	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.021	0.979	0.000
T43.2 Other and unspecified antidepressants	0.021	0.979	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.020	0.980	0.000
T38.0 Glucocorticoids and synthetic analogues	0.018	0.982	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.018	0.982	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.018	0.982	0.000
T36 Poisoning by systemic antibiotics	0.018	0.982	0.000
T42.4 Benzodiazepines	0.017	0.983	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.017	0.983	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.017	0.983	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.017	0.983	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.017	0.983	0.000
T38.1 Thyroid hormones and substitutes	0.017	0.983	0.000
T42.1 Iminostilbenes	0.017	0.983	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.017	0.983	0.000
T42.0 Hydantoin derivatives	0.017	0.983	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.017	0.983	0.000
T38.9 Other and unspecified hormone antagonists	0.016	0.983	0.000
T38.7 Androgens and anabolic congeners	0.016	0.983	0.000
T38.5 Other oestrogens and progestogens	0.016	0.983	0.000
T38.4 Oral contraceptives	0.016	0.983	0.000
T38.2 Antithyroid drugs	0.016	0.983	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.016	0.984	0.000
T50.8 Diagnostic agents	0.016	0.984	0.000
T46.1 Calcium-channel blockers	0.016	0.984	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.016	0.984	0.000
T43.9 Psychotropic drug, unspecified	0.016	0.984	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.016	0.984	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.016	0.984	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.016	0.984	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.016	0.984	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.016	0.984	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.015	0.985	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.015	0.985	0.000
T42.3 Barbiturates	0.015	0.985	0.000
T42.2 Succinimides and oxazolidinediones	0.015	0.985	0.000
T50.4 Drugs affecting uric acid metabolism	0.015	0.985	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.015	0.985	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.015	0.985	0.000
T50.7 Analeptics and opioid receptor antagonists	0.015	0.985	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.015	0.985	0.000
T50.5 Appetite depressants	0.015	0.985	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.015	0.985	0.000
T50.1 Loop [high-ceiling] diuretics	0.015	0.985	0.000
T50.0 Mineralocorticoids and their antagonists	0.015	0.985	0.000
T47.0 Histamine H(2)-receptor antagonists	0.014	0.986	0.000
T36.0 Penicillins	0.014	0.986	0.000
T43.6 Psychostimulants with abuse potential	0.014	0.986	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.014	0.986	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.014	0.986	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.013	0.987	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.013	0.987	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.013	0.987	0.000
T46.7 Peripheral vasodilators	0.013	0.987	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.013	0.987	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.013	0.987	0.000
T36.3 Macrolides	0.013	0.987	0.000
T47.4 Other laxatives	0.013	0.987	0.000
T36.9 Systemic antibiotic, unspecified	0.013	0.987	0.000
T36.8 Other systemic antibiotics	0.013	0.987	0.000
T36.7 Antifungal antibiotics, systemically used	0.013	0.987	0.000
T36.6 Rifamycins	0.013	0.987	0.000
T36.5 Aminoglycosides	0.013	0.987	0.000
T36.4 Tetracyclines	0.013	0.987	0.000
T36.2 Chloramphenicol group	0.013	0.987	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.013	0.987	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.012	0.988	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.012	0.988	0.000
T47.7 Emetics	0.012	0.988	0.000
T47.6 Antidiarrhoeal drugs	0.012	0.988	0.000
T47.5 Digestants	0.012	0.988	0.000
T47.3 Saline and osmotic laxatives	0.012	0.988	0.000
T47.2 Stimulant laxatives	0.012	0.988	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.012	0.988	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.012	0.988	0.000
T37.5 Antiviral drugs	0.012	0.988	0.000
T37.4 Anthelminthics	0.012	0.988	0.000
T37.3 Other antiprotozoal drugs	0.012	0.988	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.012	0.988	0.000
T37.1 Antimycobacterial drugs	0.012	0.988	0.000
T37.0 Sulphonamides	0.012	0.988	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.012	0.988	0.000
T41.5 Therapeutic gases	0.011	0.988	0.000
T41.4 Anaesthetic, unspecified	0.011	0.988	0.000
T41.3 Local anaesthetics	0.011	0.988	0.000
T41.2 Other and unspecified general anaesthetics	0.011	0.988	0.000
T41.1 Intravenous anaesthetics	0.011	0.988	0.000
T41.0 Inhaled anaesthetics	0.011	0.988	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.011	0.988	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.011	0.988	0.000
T48.5 Anti-common-cold drugs	0.011	0.988	0.000
T48.4 Expectorants	0.011	0.988	0.000
T48.3 Antitussives	0.011	0.988	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.011	0.988	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.011	0.988	0.000
T48.0 Oxytocic drugs	0.011	0.988	0.000
T49.9 Topical agent, unspecified	0.011	0.988	0.000
T49.8 Other topical agents	0.011	0.988	0.000
T49.7 Dental drugs, topically applied	0.011	0.988	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.011	0.988	0.000
T49.5 Ophthalmological drugs and preparations	0.011	0.988	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.011	0.988	0.000
T49.3 Emollients, demulcents and protectants	0.011	0.988	0.000
T49.2 Local astringents and local detergents	0.011	0.988	0.000
T49.1 Antipruritics	0.011	0.988	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.011	0.988	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.011	0.988	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.011	0.989	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.011	0.989	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.011	0.989	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.011	0.989	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.011	0.989	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.011	0.989	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.011	0.989	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.011	0.989	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.011	0.989	0.000
T44.0 Anticholinesterase agents	0.011	0.989	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.010	0.990	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.009	0.991	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.009	0.991	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.009	0.991	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.008	0.991	0.000
T45.8 Other primarily systemic and haematological agents	0.008	0.991	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.008	0.991	0.000
T45.6 Fibrinolysis-affecting drugs	0.008	0.991	0.000
T45.4 Iron and its compounds	0.008	0.991	0.000
T45.3 Enzymes, not elsewhere classified	0.008	0.991	0.000
I08.0 Disorders of both mitral and aortic valves	0.000	0.992	0.008
T45.2 Vitamins, not elsewhere classified	0.008	0.992	0.000
Z22.3 Carrier of other specified bacterial diseases	0.008	0.992	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.008	0.992	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.007	0.993	0.000
T45.0 Antiallergic and antiemetic drugs	0.007	0.993	0.000
O72.1 Other immediate postpartum haemorrhage	0.007	0.993	0.000
T39.4 Antirheumatics, not elsewhere classified	0.007	0.993	0.000
T39.2 Pyrazolone derivatives	0.007	0.993	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.006	0.994	0.000
T45.5 Anticoagulants	0.006	0.994	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.005	0.994	0.000
C67.2 Lateral wall of bladder	0.000	0.995	0.005
I84.7 Unspecified thrombosed haemorrhoids	0.005	0.995	0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.005	0.995	0.000
Z73.9 Problem related to life-management difficulty, unspecified	0.005	0.995	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.005	0.995	0.000
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.000	0.995	0.005
T39.0 Salicylates	0.005	0.995	0.000
C32.9 Larynx, unspecified	0.005	0.995	0.000
C67.8 Overlapping lesion of bladder	0.000	0.996	0.004
C67 Malignant neoplasm of bladder	0.000	0.996	0.004
Z73.3 Stress, not elsewhere classified	0.004	0.996	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.004	0.996	0.000
C67.1 Dome of bladder	0.000	0.996	0.004
Z73 Problems related to life-management difficulty	0.004	0.996	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.003	0.996	0.000
T40.8 Lysergide [LSD]	0.003	0.996	0.000
T40.7 Cannabis (derivatives)	0.003	0.996	0.000
T40.5 Cocaine	0.003	0.996	0.000
T40.3 Methadone	0.003	0.996	0.000
T40.1 Heroin	0.003	0.996	0.000
T40.0 Opium	0.003	0.996	0.000
C67.4 Posterior wall of bladder	0.000	0.996	0.004
N42.1 Congestion and haemorrhage of prostate	0.004	0.996	0.000
C67.5 Bladder neck	0.000	0.996	0.003
C32 Malignant neoplasm of larynx	0.003	0.997	0.000
C67.7 Urachus	0.000	0.997	0.003
C67.0 Trigone of bladder	0.000	0.997	0.003
J92.9 Pleural plaque without asbestos	0.000	0.997	0.003
C67.6 Ureteric orifice	0.000	0.997	0.003
S62.61 Fracture of other finger (open)	0.000	0.997	0.003
C32.0 Glottis	0.003	0.997	0.000
C67.3 Anterior wall of bladder	0.000	0.997	0.003
F25.0 Schizoaffective disorder, manic type	0.003	0.997	0.000
M79.00 Rheumatism, unspecified (Multiple sites)	0.000	0.997	0.003
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs	0.003	0.997	0.000
S29.9 Unspecified injury of thorax	0.003	0.997	0.000
Z73.8 Other problems related to life-management difficulty	0.003	0.997	0.000
Z73.5 Social role conflict, not elsewhere classified	0.003	0.997	0.000
Z73.4 Inadequate social skills, not elsewhere classified	0.003	0.997	0.000
Z73.2 Lack of relaxation and leisure	0.003	0.997	0.000
Z73.1 Accentuation of personality traits	0.003	0.997	0.000
Z73.0 Burn-out	0.003	0.997	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.997	0.003
C32.1 Supraglottis	0.003	0.997	0.000
M54.12 Radiculopathy (Cervical region)	0.003	0.997	0.000
N75.1 Abscess of Bartholin's gland	0.000	0.997	0.003
T39.1 4-Aminophenol derivatives	0.003	0.997	0.000
F25 Schizoaffective disorders	0.003	0.997	0.000
M79.09 Rheumatism, unspecified (Site unspecified)	0.000	0.997	0.003
F25.9 Schizoaffective disorder, unspecified	0.003	0.997	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.000	0.997	0.003
C32.8 Overlapping lesion of larynx	0.003	0.997	0.000
C32.3 Laryngeal cartilage	0.003	0.997	0.000
C32.2 Subglottis	0.003	0.997	0.000
Z35.1 Supervision of pregnancy with history of abortive outcome	0.003	0.997	0.000
Z73.6 Limitation of activities due to disability	0.003	0.997	0.000
O61.0 Failed medical induction of labour	0.003	0.997	0.000
D63.0 Anaemia in neoplastic disease	0.003	0.997	0.000
F25.2 Schizoaffective disorder, mixed type	0.003	0.997	0.000
F25.1 Schizoaffective disorder, depressive type	0.003	0.997	0.000
N11 Chronic tubulo-interstitial nephritis	0.000	0.997	0.003
T40.6 Other and unspecified narcotics	0.002	0.997	0.001
I70.00 Atherosclerosis of aorta (without gangrene)	0.003	0.997	0.000
K59.1 Functional diarrhoea	0.003	0.997	0.000
Z74.0 Reduced mobility	0.003	0.997	0.000
T51.0 Ethanol	0.002	0.998	0.000
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.000	0.998	0.002
F25.8 Other schizoaffective disorders	0.002	0.998	0.000
L08.8 Other specified local infections of skin and subcutaneous tissue	0.000	0.998	0.002
T40.4 Other synthetic narcotics	0.002	0.998	0.001
T40.2 Other opioids	0.002	0.998	0.000
C83.3 Large cell (diffuse)	0.002	0.998	0.000
M79.0 Rheumatism, unspecified	0.000	0.998	0.002
Y84.8 Other medical procedures	0.002	0.998	0.000
C64-C68 Malignant neoplasms of urinary tract	0.000	0.998	0.002
J86.9 Pyothorax without fistula	0.000	0.998	0.002
Z22 Carrier of infectious disease	0.002	0.998	0.000
C65 Malignant neoplasm of renal pelvis	0.000	0.998	0.002
C64 Malignant neoplasm of kidney, except renal pelvis	0.000	0.998	0.002
N11.8 Other chronic tubulo-interstitial nephritis	0.000	0.998	0.002
T51.9 Alcohol, unspecified	0.002	0.998	0.000
N11.1 Chronic obstructive pyelonephritis	0.000	0.998	0.002
H50.2 Vertical strabismus	0.002	0.998	0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.002	0.998	0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.002	0.998	0.000
H50.0 Convergent concomitant strabismus	0.002	0.998	0.000
M48.09 Spinal stenosis (Site unspecified)	0.002	0.998	0.000
T51 Toxic effect of alcohol	0.002	0.998	0.000
M79.07 Rheumatism, unspecified (Ankle and foot)	0.000	0.998	0.002
M79.05 Rheumatism, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
M79.04 Rheumatism, unspecified (Hand)	0.000	0.998	0.002
M79.03 Rheumatism, unspecified (Forearm)	0.000	0.998	0.002
M79.02 Rheumatism, unspecified (Upper arm)	0.000	0.998	0.002
M79.06 Rheumatism, unspecified (Lower leg)	0.000	0.998	0.002
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.000	0.998	0.002
Z22.9 Carrier of infectious disease, unspecified	0.002	0.998	0.000
Z22.6 Carrier of human T-lymphotropic virus type 1 [HTLV-1] infection	0.002	0.998	0.000
Z22.4 Carrier of infections with a predominantly sexual mode of transmission	0.002	0.998	0.000
Z22.2 Carrier of diphtheria	0.002	0.998	0.000
Z22.0 Carrier of typhoid	0.002	0.998	0.000
M79.01 Rheumatism, unspecified (Shoulder region)	0.000	0.998	0.002
M79.08 Rheumatism, unspecified (Other)	0.000	0.998	0.002
Z22.8 Carrier of other infectious diseases	0.002	0.998	0.000
C68 Malignant neoplasm of other and unspecified urinary organs	0.000	0.998	0.002
H50.5 Heterophoria	0.002	0.998	0.000
H74.0 Tympanosclerosis	0.000	0.998	0.002
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.002	0.998	0.000
O62.0 Primary inadequate contractions	0.002	0.998	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.000	0.998	0.002
S19.9 Unspecified injury of neck	0.002	0.998	0.000
E83.1 Disorders of iron metabolism	0.002	0.998	0.000
G11.9 Hereditary ataxia, unspecified	0.002	0.998	0.000
O72 Postpartum haemorrhage	0.002	0.998	0.000
H50.4 Other and unspecified heterotropia	0.002	0.998	0.000
S29 Other and unspecified injuries of thorax	0.002	0.998	0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.000	0.998	0.002
Z22.1 Carrier of other intestinal infectious diseases	0.002	0.998	0.000
C92.0 Acute myeloid leukaemia	0.000	0.998	0.002
J01.9 Acute sinusitis, unspecified	0.002	0.998	0.000
D47.1 Chronic myeloproliferative disease	0.000	0.998	0.002
T51.8 Other alcohols	0.002	0.998	0.000
T51.3 Fusel oil	0.002	0.998	0.000
T51.2 2-Propanol	0.002	0.998	0.000
T51.1 Methanol	0.002	0.998	0.000
H50 Other strabismus	0.002	0.998	0.000
F01.9 Vascular dementia, unspecified	0.002	0.998	0.000
S29.8 Other specified injuries of thorax	0.002	0.998	0.000
R61.0 Localised hyperhidrosis	0.002	0.998	0.000
F22.0 Delusional disorder	0.002	0.998	0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.000	0.998	0.002
E24.9 Cushing's syndrome, unspecified	0.002	0.998	0.000
S29.0 Injury of muscle and tendon at thorax level	0.002	0.998	0.000
C68.8 Overlapping lesion of urinary organs	0.000	0.998	0.001
C68.1 Paraurethral glands	0.000	0.998	0.001
H50.8 Other specified strabismus	0.002	0.998	0.000
N76.0 Acute vaginitis	0.002	0.998	0.000
O72.3 Postpartum coagulation defects	0.001	0.998	0.000
F22 Persistent delusional disorders	0.002	0.998	0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.002	0.998	0.000
C68.9 Urinary organ, unspecified	0.000	0.998	0.001
C68.0 Urethra	0.000	0.998	0.001
I70.0 Atherosclerosis of aorta	0.001	0.998	0.000
S29.7 Multiple injuries of thorax	0.001	0.998	0.000
Y42.5 Other oestrogens and progestogens	0.002	0.998	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.002	0.998	0.000
M88.99 Paget's disease of bone, unspecified (Site unspecified)	0.000	0.998	0.001
C14.0 Pharynx, unspecified	0.001	0.998	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.001	0.998	0.000
H50.6 Mechanical strabismus	0.001	0.998	0.000
H50.3 Intermittent heterotropia	0.001	0.998	0.000
T78.3 Angioneurotic oedema	0.001	0.998	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.000	0.999	0.001
S92.20 Fracture of other tarsal bone(s) (closed)	0.001	0.999	0.000
B97 Viral agents as the cause of diseases classified to other chapters	0.001	0.999	0.000
D11.7 Other major salivary glands	0.001	0.999	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.999	0.001
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)	0.001	0.999	0.000
Q60.2 Renal agenesis, unspecified	0.000	0.999	0.001
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.001	0.999	0.000
T63.4 Venom of other arthropods	0.000	0.999	0.001
W10.8 Other specified place	0.001	0.999	0.000
M79.15 Myalgia (Pelvic region and thigh)	0.000	0.999	0.001
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.000	0.999	0.001
R81 Glycosuria	0.001	0.999	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.001	0.999	0.000
H47.1 Papilloedema, unspecified	0.001	0.999	0.000
H70.9 Mastoiditis, unspecified	0.001	0.999	0.000
D47.4 Osteomyelofibrosis	0.000	0.999	0.001
F22.9 Persistent delusional disorder, unspecified	0.001	0.999	0.000
F43.2 Adjustment disorders	0.000	0.999	0.001
I70.01 Atherosclerosis of aorta (with gangrene)	0.001	0.999	0.000
C09.1 Tonsillar pillar (anterior) (posterior)	0.001	0.999	0.000
D63.1 Anaemia in other chronic diseases classified elsewhere	0.001	0.999	0.000
F22.8 Other persistent delusional disorders	0.001	0.999	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.999	0.001
M48.5 Collapsed vertebra, not elsewhere classified	0.001	0.999	0.000
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)	0.001	0.999	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.001	0.999	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.000	0.999	0.001
O72.2 Delayed and secondary postpartum haemorrhage	0.001	0.999	0.000
T14.1 Open wound of unspecified body region	0.000	0.999	0.001
Z36.0 Antenatal screening for chromosomal anomalies	0.001	0.999	0.000
Z74 Problems related to care-provider dependency	0.001	0.999	0.000
S61.9 Open wound of wrist and hand, part unspecified	0.001	0.999	0.000
W60.0 Home	0.001	0.999	0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.000	0.999	0.001
B97.6 Parvovirus as the cause of diseases classified to other chapters	0.001	0.999	0.000
B97.5 Reovirus as the cause of diseases classified to other chapters	0.001	0.999	0.000
B97.3 Retrovirus as the cause of diseases classified to other chapters	0.001	0.999	0.000
B97.2 Coronavirus as the cause of diseases classified to other chapters	0.001	0.999	0.000
B97.1 Enterovirus as the cause of diseases classified to other chapters	0.001	0.999	0.000
B97.0 Adenovirus as the cause of diseases classified to other chapters	0.001	0.999	0.000
W55.8 Other specified place	0.001	0.999	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.000	0.999	0.001
J01.8 Other acute sinusitis	0.001	0.999	0.000
Q87.4 Marfan's syndrome	0.000	0.999	0.001
Z74.2 Need for assistance at home and no other household member able to render care	0.001	0.999	0.000
Z74.1 Need for assistance with personal care	0.001	0.999	0.000
M54.17 Radiculopathy (Lumbosacral region)	0.001	0.999	0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.000	0.999	0.001
C83.1 Small cleaved cell (diffuse)	0.001	0.999	0.000
D28.0 Vulva	0.001	0.999	0.000
I09.9 Rheumatic heart disease, unspecified	0.000	0.999	0.001
W55.0 Home	0.001	0.999	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.999	0.001
F28 Other nonorganic psychotic disorders	0.001	0.999	0.000
F24 Induced delusional disorder	0.001	0.999	0.000
F21 Schizotypal disorder	0.001	0.999	0.000
K29.4 Chronic atrophic gastritis	0.001	0.999	0.000
R79.9 Abnormal finding of blood chemistry, unspecified	0.001	0.999	0.000
F20 Schizophrenia	0.001	0.999	0.000
I08 Multiple valve diseases	0.000	0.999	0.001
W55 Bitten or struck by other mammals	0.001	0.999	0.000
M54.10 Radiculopathy (Multiple sites in spine)	0.001	0.999	0.000
J01.1 Acute frontal sinusitis	0.001	0.999	0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.001	0.999	0.000
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)	0.001	0.999	0.000
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)	0.001	0.999	0.000
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)	0.001	0.999	0.000
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)	0.001	0.999	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.000	0.999	0.001
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.000	0.999	0.001
F20.8 Other schizophrenia	0.001	0.999	0.000
M88.9 Paget's disease of bone, unspecified	0.000	0.999	0.001
Y46.4 Iminostilbenes	0.001	0.999	0.000
C66 Malignant neoplasm of ureter	0.000	0.999	0.001
H46 Optic neuritis	0.001	0.999	0.000
M54.19 Radiculopathy (Site unspecified)	0.001	0.999	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.000	0.999	0.001
F20.5 Residual schizophrenia	0.001	0.999	0.000
M54.1 Radiculopathy	0.001	0.999	0.000
Q61.0 Congenital single renal cyst	0.000	0.999	0.001
X68.9 Unspecified place	0.001	0.999	0.000
Z74.3 Need for continuous supervision	0.001	0.999	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.000	0.999	0.001
F20.0 Paranoid schizophrenia	0.001	0.999	0.000
G11.4 Hereditary spastic paraplegia	0.001	0.999	0.000
H74.1 Adhesive middle ear disease	0.000	0.999	0.001
M84.4 Pathological fracture, not elsewhere classified	0.000	0.999	0.001
N34.2 Other urethritis	0.000	0.999	0.001
O61 Failed induction of labour	0.001	0.999	0.000
M54.88 Other dorsalgia (Sacral and sacrococcygeal region)	0.001	0.999	0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.000	0.999	0.001
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.000	0.999	0.001
H25.9 Senile cataract, unspecified	0.000	0.999	0.001
H74.3 Other acquired abnormalities of ear ossicles	0.000	0.999	0.001
N42.9 Disorder of prostate, unspecified	0.001	0.999	0.000
O61.9 Failed induction of labour, unspecified	0.001	0.999	0.000
W55.7 Farm	0.001	0.999	0.000
J86 Pyothorax	0.000	0.999	0.001
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)	0.001	0.999	0.000
E24.0 Pituitary-dependent Cushing's disease	0.001	0.999	0.000
F20.6 Simple schizophrenia	0.001	0.999	0.000
F20.4 Postschizophrenic depression	0.001	0.999	0.000
F20.3 Undifferentiated schizophrenia	0.001	0.999	0.000
F20.2 Catatonic schizophrenia	0.001	0.999	0.000
F20.1 Hebephrenic schizophrenia	0.001	0.999	0.000
W55.9 Unspecified place	0.001	0.999	0.000
W55.5 Trade and service area	0.001	0.999	0.000
W55.6 Industrial and construction area	0.001	0.999	0.000
W55.4 Street and highway	0.001	0.999	0.000
W55.3 Sports and athletics area	0.001	0.999	0.000
W55.2 School, other institution and public administrative area	0.001	0.999	0.000
W55.1 Residential institution	0.001	0.999	0.000
W57.8 Other specified place	0.001	0.999	0.000
G11 Hereditary ataxia	0.001	0.999	0.000
M24.51 Contracture of joint (Shoulder region)	0.000	0.999	0.001
M25.84 Other specified joint disorders (Hand)	0.001	0.999	0.000
M88.98 Paget's disease of bone, unspecified (Other)	0.000	0.999	0.001
M88.97 Paget's disease of bone, unspecified (Ankle and foot)	0.000	0.999	0.001
M88.96 Paget's disease of bone, unspecified (Lower leg)	0.000	0.999	0.001
M88.95 Paget's disease of bone, unspecified (Pelvic region and thigh)	0.000	0.999	0.001
M88.94 Paget's disease of bone, unspecified (Hand)	0.000	0.999	0.001
M88.93 Paget's disease of bone, unspecified (Forearm)	0.000	0.999	0.001
M88.92 Paget's disease of bone, unspecified (Upper arm)	0.000	0.999	0.001
M88.91 Paget's disease of bone, unspecified (Shoulder region)	0.000	0.999	0.001
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.999	0.001
D68.9 Coagulation defect, unspecified	0.001	0.999	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.001	0.999	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.000	0.999	0.001
S05.8 Other injuries of eye and orbit	0.001	0.999	0.000
W51.9 Unspecified place	0.001	0.999	0.000
A46 Erysipelas	0.000	0.999	0.001
M54.15 Radiculopathy (Thoracolumbar region)	0.001	0.999	0.000
M54.13 Radiculopathy (Cervicothoracic region)	0.001	0.999	0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)	0.001	0.999	0.000
M54.89 Other dorsalgia (Site unspecified)	0.001	0.999	0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.000	0.999	0.001
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.000	0.999	0.001
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.000	0.999	0.001
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.000	0.999	0.001
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.000	0.999	0.001
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.000	0.999	0.001
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.000	0.999	0.001
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.000	0.999	0.001
G12.2 Motor neuron disease	0.000	0.999	0.001
I05.0 Mitral stenosis	0.000	0.999	0.001
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.001	0.999	0.000
W60 Contact with plant thorns and spines and sharp leaves	0.001	0.999	0.000
N90.9 Noninflammatory disorder of vulva and perineum, unspecified	0.000	0.999	0.001
O61.8 Other failed induction of labour	0.001	0.999	0.000
T83.1 Mechanical complication of other urinary devices and implants	0.000	0.999	0.001
Z74.9 Problem related to care-provider dependency, unspecified	0.001	0.999	0.000
I99 Other and unspecified disorders of circulatory system	0.000	0.999	0.001
J01 Acute sinusitis	0.001	0.999	0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.001	0.999	0.000
W55.58 Bitten or struck by other mammals; Trade and service area;While engaged in other specified activities	0.001	0.999	0.000
W55.99 Bitten or struck by other mammals: Unspecified place: During unspecified activity	0.001	0.999	0.000
C10.9 Oropharynx, unspecified	0.001	0.999	0.000
D10.1 Tongue	0.001	0.999	0.000
G11.8 Other hereditary ataxias	0.001	0.999	0.000
G11.3 Cerebellar ataxia with defective DNA repair	0.001	0.999	0.000
G11.2 Late-onset cerebellar ataxia	0.001	0.999	0.000
G11.1 Early-onset cerebellar ataxia	0.001	0.999	0.000
G11.0 Congenital nonprogressive ataxia	0.001	0.999	0.000
J34.0 Abscess, furuncle and carbuncle of nose	0.001	0.999	0.000
K35.8 Acute appendicitis, other and unspecified	0.000	0.999	0.001
N76.6 Ulceration of vulva	0.000	0.999	0.001
T54.9 Corrosive substance, unspecified	0.001	0.999	0.000
W50.8 Other specified place	0.001	0.999	0.000
Z22.5 Carrier of viral hepatitis	0.001	0.999	0.000
C09 Malignant neoplasm of tonsil	0.001	0.999	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.001	0.999	0.000
T58 Toxic effect of carbon monoxide	0.001	0.999	0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.001	0.999	0.000
M54.14 Radiculopathy (Thoracic region)	0.001	0.999	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.000	0.999	0.001
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.000	0.999	0.001
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.000	0.999	0.001
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.000	0.999	0.001
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.000	0.999	0.001
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.000	0.999	0.001
B97.4 Respiratory synctial virus as the cause of diseases classified to other chapters	0.001	0.999	0.000
D31.3 Choroid	0.001	0.999	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.999	0.001
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified	0.000	0.999	0.001
T87.6 Other and unspecified complications of amputation stump	0.000	0.999	0.001
F29 Unspecified nonorganic psychosis	0.001	0.999	0.000
W51 Striking against or bumped into by another person	0.001	0.999	0.000
M54.46 Lumbago with sciatica (Lumbar region)	0.001	0.999	0.000
M54.84 Other dorsalgia (Thoracic region)	0.001	0.999	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.000	0.999	0.001
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.000	0.999	0.001
C14.8 Overlapping lesion of lip, oral cavity and pharynx	0.001	0.999	0.000
C14.2 Waldeyer's ring	0.001	0.999	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.000	0.999	0.001
H74.8 Other specified disorders of middle ear and mastoid	0.000	0.999	0.001
J01.4 Acute pansinusitis	0.001	0.999	0.000
J01.3 Acute sphenoidal sinusitis	0.001	0.999	0.000
L29.9 Pruritus, unspecified	0.001	0.999	0.000
L60.9 Nail disorder, unspecified	0.001	0.999	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.001	0.999	0.000
O44.0 Placenta praevia specified as without haemorrhage	0.001	0.999	0.000
Q67.6 Pectus excavatum	0.001	0.999	0.000
W01.1 Residential institution	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations