TreeWAS – Variant ID: rs6892553

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I30-I52 Other forms of heart disease	0.041	0.959	0.000
I34 Nonrheumatic mitral valve disorders	0.040	0.959	0.000
I34.0 Mitral (valve) insufficiency	0.039	0.961	0.000
I45 Other conduction disorders	0.039	0.961	0.000
I44 Atrioventricular and left bundle-branch block	0.039	0.961	0.000
I35 Nonrheumatic aortic valve disorders	0.038	0.962	0.000
I51 Complications and ill-defined descriptions of heart disease	0.037	0.963	0.000
I35.1 Aortic (valve) insufficiency	0.036	0.964	0.000
I50 Heart failure	0.035	0.965	0.000
I45.1 Other and unspecified right bundle-branch block	0.035	0.965	0.000
I44.0 Atrioventricular block, first degree	0.035	0.965	0.000
I34.1 Mitral (valve) prolapse	0.035	0.965	0.000
I51.9 Heart disease, unspecified	0.032	0.968	0.000
I50.0 Congestive heart failure	0.032	0.968	0.000
I45.3 Trifascicular block	0.032	0.968	0.000
I44.2 Atrioventricular block, complete	0.032	0.968	0.000
I46 Cardiac arrest	0.031	0.968	0.000
I33 Acute and subacute endocarditis	0.030	0.969	0.000
I36 Nonrheumatic tricuspid valve disorders	0.030	0.970	0.000
I45.2 Bifascicular block	0.030	0.970	0.000
I45.5 Other specified heart block	0.030	0.970	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.030	0.970	0.000
I44.7 Left bundle-branch block, unspecified	0.030	0.970	0.000
I52 Other heart disorders in diseases classified elsewhere	0.030	0.970	0.000
I48 Atrial fibrillation and flutter	0.030	0.970	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.030	0.970	0.000
I41 Myocarditis in diseases classified elsewhere	0.030	0.970	0.000
I40 Acute myocarditis	0.030	0.970	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.030	0.970	0.000
I37 Pulmonary valve disorders	0.030	0.970	0.000
I32 Pericarditis in diseases classified elsewhere	0.030	0.970	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.029	0.971	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.029	0.971	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.029	0.971	0.000
I51.8 Other ill-defined heart diseases	0.029	0.971	0.000
I44.3 Other and unspecified atrioventricular block	0.029	0.971	0.000
I44.6 Other and unspecified fascicular block	0.028	0.972	0.000
I31 Other diseases of pericardium	0.028	0.972	0.000
I45.8 Other specified conduction disorders	0.028	0.972	0.000
I45.4 Nonspecific intraventricular block	0.028	0.972	0.000
I45.0 Right fascicular block	0.028	0.972	0.000
I44.5 Left posterior fascicular block	0.028	0.972	0.000
I44.4 Left anterior fascicular block	0.028	0.972	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.028	0.972	0.000
I45.9 Conduction disorder, unspecified	0.028	0.972	0.000
I44.1 Atrioventricular block, second degree	0.028	0.972	0.000
I42 Cardiomyopathy	0.027	0.973	0.000
I35.9 Aortic valve disorder, unspecified	0.027	0.973	0.000
I46.9 Cardiac arrest, unspecified	0.027	0.973	0.000
I30 Acute pericarditis	0.027	0.973	0.000
I45.6 Preexcitation syndrome	0.027	0.973	0.000
I35.0 Aortic (valve) stenosis	0.027	0.973	0.000
I51.6 Cardiovascular disease, unspecified	0.026	0.973	0.000
I51.5 Myocardial degeneration	0.026	0.973	0.000
I51.4 Myocarditis, unspecified	0.026	0.973	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.026	0.973	0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.026	0.973	0.000
I51.0 Cardiac septal defect, acquired	0.026	0.973	0.000
I35.8 Other aortic valve disorders	0.026	0.973	0.000
I50.1 Left ventricular failure	0.026	0.974	0.000
I38 Endocarditis, valve unspecified	0.025	0.975	0.000
I47 Paroxysmal tachycardia	0.024	0.976	0.000
I51.7 Cardiomegaly	0.024	0.976	0.000
I33.0 Acute and subacute infective endocarditis	0.023	0.977	0.000
I46.1 Sudden cardiac death, so described	0.023	0.977	0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.022	0.977	0.000
I33.9 Acute endocarditis, unspecified	0.022	0.978	0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.022	0.978	0.000
I36.8 Other nonrheumatic tricuspid valve disorders	0.022	0.978	0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.022	0.978	0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.022	0.978	0.000
I32.8 Pericarditis in other diseases classified elsewhere	0.021	0.978	0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.021	0.978	0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.021	0.978	0.000
I37.9 Pulmonary valve disorder, unspecified	0.021	0.978	0.000
I37.8 Other pulmonary valve disorders	0.021	0.978	0.000
I37.2 Pulmonary valve stenosis with insufficiency	0.021	0.978	0.000
I37.1 Pulmonary valve insufficiency	0.021	0.978	0.000
I37.0 Pulmonary valve stenosis	0.021	0.978	0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.021	0.978	0.000
I39.4 Multiple valve disorders in diseases classified elsewhere	0.021	0.978	0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.021	0.978	0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.021	0.978	0.000
I39.1 Aortic valve disorders in diseases classified elsewhere	0.021	0.978	0.000
I39.0 Mitral valve disorders in diseases classified elsewhere	0.021	0.978	0.000
I40.9 Acute myocarditis, unspecified	0.021	0.978	0.000
I40.8 Other acute myocarditis	0.021	0.978	0.000
I40.1 Isolated myocarditis	0.021	0.978	0.000
I40.0 Infective myocarditis	0.021	0.978	0.000
I41.8 Myocarditis in other diseases classified elsewhere	0.021	0.978	0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.021	0.978	0.000
I41.1 Myocarditis in viral diseases classified elsewhere	0.021	0.978	0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.021	0.978	0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.021	0.978	0.000
I43.2 Cardiomyopathy in nutritional diseases	0.021	0.978	0.000
I43.1 Cardiomyopathy in metabolic diseases	0.021	0.978	0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.021	0.978	0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.021	0.978	0.000
I48.4 Atypical atrial flutter	0.021	0.978	0.000
I48.3 Typical atrial flutter	0.021	0.978	0.000
I48.2 Chronic atrial fibrillation	0.021	0.978	0.000
I48.1 Persistent atrial fibrillation	0.021	0.978	0.000
I48.0 Paroxysmal atrial fibrillation	0.021	0.978	0.000
I52.8 Other heart disorders in other diseases classified elsewhere	0.021	0.978	0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.021	0.978	0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.021	0.978	0.000
I50.9 Heart failure, unspecified	0.021	0.979	0.000
I42.8 Other cardiomyopathies	0.021	0.979	0.000
I31.3 Pericardial effusion (noninflammatory)	0.021	0.979	0.000
I31.8 Other specified diseases of pericardium	0.020	0.980	0.000
I31.2 Haemopericardium, not elsewhere classified	0.020	0.980	0.000
I31.1 Chronic constrictive pericarditis	0.020	0.980	0.000
I31.0 Chronic adhesive pericarditis	0.020	0.980	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.020	0.980	0.000
I42.6 Alcoholic cardiomyopathy	0.020	0.980	0.000
I42.5 Other restrictive cardiomyopathy	0.020	0.980	0.000
I42.4 Endocardial fibroelastosis	0.020	0.980	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.020	0.980	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.020	0.980	0.000
I30.8 Other forms of acute pericarditis	0.019	0.980	0.000
I30.1 Infective pericarditis	0.019	0.980	0.000
I30.0 Acute nonspecific idiopathic pericarditis	0.019	0.980	0.000
I47.2 Ventricular tachycardia	0.019	0.980	0.000
I42.2 Other hypertrophic cardiomyopathy	0.019	0.981	0.000
I46.0 Cardiac arrest with successful resuscitation	0.019	0.981	0.000
I42.0 Dilated cardiomyopathy	0.019	0.981	0.000
I31.9 Disease of pericardium, unspecified	0.019	0.981	0.000
I49 Other cardiac arrhythmias	0.019	0.981	0.000
I42.9 Cardiomyopathy, unspecified	0.018	0.982	0.000
I47.0 Reentry ventricular arrhythmia	0.017	0.983	0.000
I30.9 Acute pericarditis, unspecified	0.016	0.983	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.016	0.983	0.000
I49.3 Ventricular premature depolarisation	0.016	0.984	0.000
I49.8 Other specified cardiac arrhythmias	0.014	0.986	0.000
I49.2 Junctional premature depolarisation	0.013	0.986	0.000
M47.99 Spondylosis, unspecified (Site unspecified)	0.000	0.987	0.013
I49.1 Atrial premature depolarisation	0.013	0.987	0.000
I49.0 Ventricular fibrillation and flutter	0.013	0.987	0.000
M47.9 Spondylosis, unspecified	0.000	0.988	0.012
I49.5 Sick sinus syndrome	0.012	0.988	0.000
M47.92 Spondylosis, unspecified (Cervical region)	0.000	0.988	0.012
I49.4 Other and unspecified premature depolarisation	0.011	0.989	0.000
M47.96 Spondylosis, unspecified (Lumbar region)	0.000	0.989	0.011
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.000	0.991	0.009
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)	0.000	0.991	0.009
M47.95 Spondylosis, unspecified (Thoracolumbar region)	0.000	0.991	0.009
M47.94 Spondylosis, unspecified (Thoracic region)	0.000	0.991	0.009
M47.93 Spondylosis, unspecified (Cervicothoracic region)	0.000	0.991	0.009
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)	0.000	0.991	0.009
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.000	0.992	0.008
I47.1 Supraventricular tachycardia	0.008	0.992	0.000
I49.9 Cardiac arrhythmia, unspecified	0.007	0.992	0.000
N80.3 Endometriosis of pelvic peritoneum	0.000	0.993	0.007
K43.9 Ventral hernia without obstruction or gangrene	0.000	0.994	0.006
N80 Endometriosis	0.000	0.995	0.005
H52.1 Myopia	0.000	0.995	0.005
N80.8 Other endometriosis	0.000	0.995	0.005
N80.0 Endometriosis of uterus	0.000	0.995	0.005
N80.1 Endometriosis of ovary	0.000	0.995	0.005
M47 Spondylosis	0.000	0.995	0.005
L72.1 Trichilemmal cyst	0.000	0.996	0.004
N80.6 Endometriosis in cutaneous scar	0.000	0.996	0.004
N80.5 Endometriosis of intestine	0.000	0.996	0.004
N80.4 Endometriosis of rectovaginal septum and vagina	0.000	0.996	0.004
N80.2 Endometriosis of Fallopian tube	0.000	0.996	0.004
M47.1 Other spondylosis with myelopathy	0.000	0.996	0.004
M47.0 Anterior spinal and vertebral artery compression syndromes	0.000	0.996	0.004
K43 Ventral hernia	0.000	0.996	0.004
M17.9 Gonarthrosis, unspecified	0.000	0.997	0.003
N80.9 Endometriosis, unspecified	0.000	0.997	0.003
M47.8 Other spondylosis	0.000	0.997	0.003
M47.86 Other spondylosis (Lumbar region)	0.000	0.997	0.003
K42.9 Umbilical hernia without obstruction or gangrene	0.000	0.997	0.003
M47.2 Other spondylosis with radiculopathy	0.000	0.997	0.003
S72.00 Fracture of neck of femur (closed)	0.003	0.997	0.000
D25.1 Intramural leiomyoma of uterus	0.000	0.997	0.003
K43.0 Ventral hernia with obstruction, without gangrene	0.000	0.997	0.003
M47.09 Anterior spinal and vertebral artery compression syndromes (Site unspecified)	0.000	0.997	0.003
M47.08 Anterior spinal and vertebral artery compression syndromes (Sacral and sacrococcygeal region)	0.000	0.997	0.003
M47.07 Anterior spinal and vertebral artery compression syndromes (Lumbosacral region)	0.000	0.997	0.003
M47.06 Anterior spinal and vertebral artery compression syndromes (Lumbar region)	0.000	0.997	0.003
M47.05 Anterior spinal and vertebral artery compression syndromes (Thoracolumbar region)	0.000	0.997	0.003
M47.04 Anterior spinal and vertebral artery compression syndromes (Thoracic region)	0.000	0.997	0.003
M47.03 Anterior spinal and vertebral artery compression syndromes (Cervicothoracic region)	0.000	0.997	0.003
M47.02 Anterior spinal and vertebral artery compression syndromes (Cervical region)	0.000	0.997	0.003
M47.01 Anterior spinal and vertebral artery compression syndromes (Occipito-atlanto-axial region)	0.000	0.997	0.003
M47.00 Anterior spinal and vertebral artery compression syndromes (Multiple sites in spine)	0.000	0.997	0.003
M47.19 Other spondylosis with myelopathy (Site unspecified)	0.000	0.997	0.003
M47.18 Other spondylosis with myelopathy (Sacral and sacrococcygeal region)	0.000	0.997	0.003
M47.17 Other spondylosis with myelopathy (Lumbosacral region)	0.000	0.997	0.003
M47.16 Other spondylosis with myelopathy (Lumbar region)	0.000	0.997	0.003
M47.15 Other spondylosis with myelopathy (Thoracolumbar region)	0.000	0.997	0.003
M47.14 Other spondylosis with myelopathy (Thoracic region)	0.000	0.997	0.003
M47.13 Other spondylosis with myelopathy (Cervicothoracic region)	0.000	0.997	0.003
M47.12 Other spondylosis with myelopathy (Cervical region)	0.000	0.997	0.003
M47.11 Other spondylosis with myelopathy (Occipito-atlanto-axial region)	0.000	0.997	0.003
M47.10 Other spondylosis with myelopathy (Multiple sites in spine)	0.000	0.997	0.003
D22.3 Melanocytic naevi of other and unspecified parts of face	0.003	0.997	0.000
K43.7 Other and unspecified ventral hernia with gangrene	0.000	0.997	0.003
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene	0.000	0.997	0.003
K43.5 Parastomal hernia without obstruction or gangrene	0.000	0.997	0.003
K43.4 Parastomal hernia with gangrene	0.000	0.997	0.003
K43.3 Parastomal hernia with obstruction, without gangrene	0.000	0.997	0.003
K43.2 Incisional hernia without obstruction or gangrene	0.000	0.997	0.003
K43.1 Ventral hernia with gangrene	0.000	0.997	0.003
D25.2 Subserosal leiomyoma of uterus	0.000	0.997	0.003
K13.7 Other and unspecified lesions of oral mucosa	0.003	0.997	0.000
J47 Bronchiectasis	0.000	0.997	0.003
D25.9 Leiomyoma of uterus, unspecified	0.000	0.997	0.003
M47.80 Other spondylosis (Multiple sites in spine)	0.000	0.997	0.003
S52.10 Fracture of upper end of radius (closed)	0.003	0.997	0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.000	0.997	0.002
M47.85 Other spondylosis (Thoracolumbar region)	0.000	0.997	0.002
M47.84 Other spondylosis (Thoracic region)	0.000	0.997	0.002
M47.83 Other spondylosis (Cervicothoracic region)	0.000	0.997	0.002
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.000	0.997	0.002
D25 Leiomyoma of uterus	0.000	0.997	0.003
M47.29 Other spondylosis with radiculopathy (Site unspecified)	0.000	0.997	0.002
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)	0.000	0.997	0.002
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.000	0.997	0.002
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)	0.000	0.997	0.002
M47.24 Other spondylosis with radiculopathy (Thoracic region)	0.000	0.997	0.002
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)	0.000	0.997	0.002
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)	0.000	0.997	0.002
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)	0.000	0.997	0.002
M47.87 Other spondylosis (Lumbosacral region)	0.000	0.997	0.002
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.000	0.998	0.002
M20.5 Other deformities of toe(s) (acquired)	0.002	0.998	0.000
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified	0.000	0.998	0.002
L72 Follicular cysts of skin and subcutaneous tissue	0.000	0.998	0.002
S72.0 Fracture of neck of femur	0.002	0.998	0.000
S42.20 Fracture of upper end of humerus (closed)	0.002	0.998	0.000
K42 Umbilical hernia	0.000	0.998	0.002
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.000	0.998	0.002
M47.89 Other spondylosis (Site unspecified)	0.000	0.998	0.002
S52.1 Fracture of upper end of radius	0.002	0.998	0.000
A04.5 Campylobacter enteritis	0.000	0.998	0.002
L72.8 Other follicular cysts of skin and subcutaneous tissue	0.000	0.998	0.002
N18.5 Chronic kidney disease, stage 5	0.002	0.998	0.000
L72.2 Steatocystoma multiplex	0.000	0.998	0.002
M17 Gonarthrosis [arthrosis of knee]	0.000	0.998	0.002
S72.01 Fracture of neck of femur (open)	0.002	0.998	0.000
K42.1 Umbilical hernia with gangrene	0.000	0.998	0.002
M20.2 Hallux rigidus	0.002	0.998	0.000
S42.2 Fracture of upper end of humerus	0.002	0.998	0.000
T51.0 Ethanol	0.002	0.998	0.000
K42.0 Umbilical hernia with obstruction, without gangrene	0.000	0.998	0.002
S93.1 Dislocation of toe(s)	0.002	0.998	0.000
H52 Disorders of refraction and accommodation	0.000	0.998	0.002
S52.11 Fracture of upper end of radius (open)	0.002	0.998	0.000
S42.40 Fracture of lower end of humerus (closed)	0.002	0.998	0.000
D25.0 Submucous leiomyoma of uterus	0.000	0.998	0.002
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.000	0.998	0.002
M19.99 Arthrosis, unspecified (Site unspecified)	0.000	0.998	0.002
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.000	0.998	0.002
N30.2 Other chronic cystitis	0.000	0.998	0.002
M19.0 Primary arthrosis of other joints	0.000	0.998	0.002
Q24.9 Congenital malformation of the heart, unspecified	0.002	0.998	0.000
R49.0 Dysphonia	0.000	0.998	0.002
N63 Unspecified lump in breast	0.002	0.998	0.000
M19.01 Primary arthrosis of other joints (Shoulder region)	0.000	0.998	0.002
M17.5 Other secondary gonarthrosis	0.000	0.998	0.002
M17.4 Other secondary gonarthrosis, bilateral	0.000	0.998	0.002
M17.2 Posttraumatic gonarthrosis, bilateral	0.000	0.998	0.002
M35.3 Polymyalgia rheumatica	0.000	0.998	0.002
S42.4 Fracture of lower end of humerus	0.002	0.998	0.000
M47.82 Other spondylosis (Cervical region)	0.000	0.998	0.002
L27.0 Generalised skin eruption due to drugs and medicaments	0.002	0.998	0.000
S72 Fracture of femur	0.002	0.998	0.000
S42.21 Fracture of upper end of humerus (open)	0.001	0.998	0.000
K92.1 Melaena	0.000	0.998	0.002
M17.0 Primary gonarthrosis, bilateral	0.000	0.998	0.002
S52 Fracture of forearm	0.002	0.998	0.000
Q24 Other congenital malformations of heart	0.001	0.998	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
M45-M49 Spondylopathies	0.000	0.998	0.002
H52.7 Disorder of refraction, unspecified	0.000	0.998	0.001
H52.6 Other disorders of refraction	0.000	0.998	0.001
H52.5 Disorders of accommodation	0.000	0.998	0.001
H52.4 Presbyopia	0.000	0.998	0.001
M17.3 Other posttraumatic gonarthrosis	0.000	0.998	0.001
Q65.8 Other congenital deformities of hip	0.001	0.998	0.000
S42 Fracture of shoulder and upper arm	0.002	0.998	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.001	0.998	0.000
M19.97 Arthrosis, unspecified (Ankle and foot)	0.000	0.998	0.002
K62.3 Rectal prolapse	0.000	0.998	0.002
N18.0 End-stage renal disease	0.001	0.998	0.000
G62.9 Polyneuropathy, unspecified	0.000	0.998	0.001
H52.2 Astigmatism	0.000	0.998	0.001
Q23.1 Congenital insufficiency of aortic valve	0.001	0.998	0.000
T51 Toxic effect of alcohol	0.001	0.998	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.001	0.998	0.000
M19.09 Primary arthrosis of other joints (Site unspecified)	0.000	0.998	0.001
M19.08 Primary arthrosis of other joints (Other)	0.000	0.998	0.001
M19.06 Primary arthrosis of other joints-Lower leg	0.000	0.998	0.001
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)	0.000	0.998	0.001
M19.03 Primary arthrosis of other joints (Forearm)	0.000	0.998	0.001
M19.02 Primary arthrosis of other joints (Upper arm)	0.000	0.998	0.001
M19.00 Primary arthrosis of other joints (Multiple sites)	0.000	0.998	0.001
S52.0 Fracture of upper end of ulna	0.001	0.998	0.000
S56.8 Injury of other and unspecified muscles and tendons at forearm level	0.001	0.998	0.000
T42.4 Benzodiazepines	0.001	0.998	0.000
Q23 Congenital malformations of aortic and mitral valves	0.001	0.998	0.000
S51 Open wound of forearm	0.001	0.998	0.000
M19.04 Primary arthrosis of other joints (Hand)	0.000	0.999	0.001
M17.1 Other primary gonarthrosis	0.000	0.999	0.001
Q61.3 Polycystic kidney, unspecified	0.001	0.999	0.000
Q61.0 Congenital single renal cyst	0.001	0.999	0.000
S51.9 Open wound of forearm, part unspecified	0.001	0.999	0.000
M19 Other arthrosis	0.000	0.999	0.001
M45 Ankylosing spondylitis	0.000	0.999	0.001
Q61 Cystic kidney disease	0.001	0.999	0.000
Q65 Congenital deformities of hip	0.001	0.999	0.000
S56 Injury of muscle and tendon at forearm level	0.001	0.999	0.000
M19.93 Arthrosis, unspecified (Forearm)	0.000	0.999	0.001
S42.41 Fracture of lower end of humerus (open)	0.001	0.999	0.000
S52.01 Fracture of upper end of ulna (open)	0.001	0.999	0.000
S51.8 Open wound of other parts of forearm	0.001	0.999	0.000
S72.9 Fracture of femur, part unspecified	0.001	0.999	0.000
S72.8 Fractures of other parts of femur	0.001	0.999	0.000
S72.7 Multiple fractures of femur	0.001	0.999	0.000
S72.3 Fracture of shaft of femur	0.001	0.999	0.000
S72.2 Subtrochanteric fracture	0.001	0.999	0.000
S50-S59 Injuries to the elbow and forearm	0.001	0.999	0.000
N30.3 Trigonitis	0.000	0.999	0.001
Q24.8 Other specified congenital malformations of heart	0.001	0.999	0.000
Q24.6 Congenital heart block	0.001	0.999	0.000
Q24.5 Malformation of coronary vessels	0.001	0.999	0.000
Q24.4 Congenital subaortic stenosis	0.001	0.999	0.000
Q24.3 Pulmonary infundibular stenosis	0.001	0.999	0.000
Q24.2 Cor triatriatum	0.001	0.999	0.000
Q24.1 Levocardia	0.001	0.999	0.000
Q24.0 Dextrocardia	0.001	0.999	0.000
S52.9 Fracture of forearm, part unspecified	0.001	0.999	0.000
S52.8 Fracture of other parts of forearm	0.001	0.999	0.000
S52.7 Multiple fractures of forearm	0.001	0.999	0.000
S52.4 Fracture of shafts of both ulna and radius	0.001	0.999	0.000
S52.3 Fracture of shaft of radius	0.001	0.999	0.000
S52.2 Fracture of shaft of ulna	0.001	0.999	0.000
M65.34 Trigger finger-Hand	0.000	0.999	0.001
A08.4 Viral intestinal infection, unspecified	0.000	0.999	0.001
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.000	0.999	0.001
R20.8 Other and unspecified disturbances of skin sensation	0.000	0.999	0.001
M49 Spondylopathies in diseases classified elsewhere	0.000	0.999	0.001
K40-K46 Hernia	0.000	0.999	0.001
H52.3 Anisometropia and aniseikonia	0.000	0.999	0.001
L23.5 Allergic contact dermatitis due to other chemical products	0.001	0.999	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.999	0.001
S42.9 Fracture of shoulder girdle, part unspecified	0.001	0.999	0.000
S42.8 Fracture of other parts of shoulder and upper arm	0.001	0.999	0.000
S42.7 Multiple fractures of clavicle, scapula and humerus	0.001	0.999	0.000
S72.1 Pertrochanteric fracture	0.001	0.999	0.000
S93.4 Sprain and strain of ankle	0.001	0.999	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.001	0.999	0.000
S93.5 Sprain and strain of toe(s)	0.001	0.999	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.001	0.999	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.001	0.999	0.000
S93.0 Dislocation of ankle joint	0.001	0.999	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.001	0.999	0.000
M19.1 Posttraumatic arthrosis of other joints	0.000	0.999	0.001
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.000	0.999	0.001
R20.2 Paraesthesia of skin	0.000	0.999	0.001
S00.1 Contusion of eyelid and periocular area	0.001	0.999	0.000
S72.4 Fracture of lower end of femur	0.001	0.999	0.000
Q21 Congenital malformations of cardiac septa	0.001	0.999	0.000
M19.9 Arthrosis, unspecified	0.000	0.999	0.001
N30.9 Cystitis, unspecified	0.000	0.999	0.001
N30.1 Interstitial cystitis (chronic)	0.000	0.999	0.001
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.001	0.999	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.001	0.999	0.000
Q23.4 Hypoplastic left heart syndrome	0.001	0.999	0.000
Q23.3 Congenital mitral insufficiency	0.001	0.999	0.000
Q23.2 Congenital mitral stenosis	0.001	0.999	0.000
Q23.0 Congenital stenosis of aortic valve	0.001	0.999	0.000
S42.1 Fracture of scapula	0.001	0.999	0.000
S51.7 Multiple open wounds of forearm	0.001	0.999	0.000
T51.8 Other alcohols	0.001	0.999	0.000
T51.3 Fusel oil	0.001	0.999	0.000
T51.2 2-Propanol	0.001	0.999	0.000
T51.1 Methanol	0.001	0.999	0.000
Q28 Other congenital malformations of circulatory system	0.001	0.999	0.000
Q27 Other congenital malformations of peripheral vascular system	0.001	0.999	0.000
Q26 Congenital malformations of great veins	0.001	0.999	0.000
Q25 Congenital malformations of great arteries	0.001	0.999	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.001	0.999	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.001	0.999	0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)	0.000	0.999	0.001
S92.50 Fracture of other toe (closed)	0.001	0.999	0.000
T51.9 Alcohol, unspecified	0.001	0.999	0.000
Y40.8 Other systemic antibiotics	0.001	0.999	0.000
K41 Femoral hernia	0.000	0.999	0.001
N30 Cystitis	0.000	0.999	0.001
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.001	0.999	0.000
S52.00 Fracture of upper end of ulna (closed)	0.001	0.999	0.000
S72.21 Subtrochanteric fracture (open)	0.001	0.999	0.000
S72.20 Subtrochanteric fracture (closed)	0.001	0.999	0.000
S72.31 Fracture of shaft of femur (open)	0.001	0.999	0.000
S72.30 Fracture of shaft of femur (closed)	0.001	0.999	0.000
S72.71 Multiple fractures of femur (open)	0.001	0.999	0.000
S72.70 Multiple fractures of femur (closed)	0.001	0.999	0.000
S72.81 Fractures of other parts of femur (open)	0.001	0.999	0.000
S72.80 Fractures of other parts of femur (closed)	0.001	0.999	0.000
S72.91 Fracture of femur, part unspecified (open)	0.001	0.999	0.000
S72.90 Fracture of femur, part unspecified (closed)	0.001	0.999	0.000
J98.1 Pulmonary collapse	0.001	0.999	0.000
M19.8 Other specified arthrosis	0.000	0.999	0.001
M19.2 Other secondary arthrosis	0.000	0.999	0.001
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.000	0.999	0.001
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.000	0.999	0.001
M45.X6 Ankylosing spondylitis (Lumbar region)	0.000	0.999	0.001
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.000	0.999	0.001
M45.X4 Ankylosing spondylitis (Thoracic region)	0.000	0.999	0.001
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.000	0.999	0.001
M45.X2 Ankylosing spondylitis (Cervical region)	0.000	0.999	0.001
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.000	0.999	0.001
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.000	0.999	0.001
Q61.9 Cystic kidney disease, unspecified	0.001	0.999	0.000
Q61.8 Other cystic kidney diseases	0.001	0.999	0.000
Q61.5 Medullary cystic kidney	0.001	0.999	0.000
Q61.4 Renal dysplasia	0.001	0.999	0.000
Q61.1 Polycystic kidney, infantile type	0.001	0.999	0.000
Q65.9 Congenital deformity of hip, unspecified	0.001	0.999	0.000
Q65.6 Unstable hip	0.001	0.999	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.001	0.999	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.001	0.999	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.001	0.999	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.001	0.999	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.001	0.999	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.001	0.999	0.000
S56.2 Injury of other flexor muscle and tendon at forearm level	0.001	0.999	0.000
S56.7 Injury of multiple muscles and tendons at forearm level	0.001	0.999	0.000
S56.5 Injury of other extensor muscle and tendon at forearm level	0.001	0.999	0.000
S56.4 Injury of extensor muscle and tendon of other finger(s) at forearm level	0.001	0.999	0.000
S56.3 Injury of extensor or abductor muscles and tendons of thumb at forearm level	0.001	0.999	0.000
S56.1 Injury of flexor muscle and tendon of other finger(s) at forearm level	0.001	0.999	0.000
S56.0 Injury of flexor muscle and tendon of thumb at forearm level	0.001	0.999	0.000
M20 Acquired deformities of fingers and toes	0.001	0.999	0.000
S90-S99 Injuries to the ankle and foot	0.001	0.999	0.000
Q60-Q64 Congenital malformations of the urinary system	0.001	0.999	0.000
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)	0.000	0.999	0.001
H52.0 Hypermetropia	0.000	0.999	0.001
Q61.2 Polycystic kidney, adult type	0.001	0.999	0.000
Q79.6 Ehlers-Danlos syndrome	0.001	0.999	0.000
S42.0 Fracture of clavicle	0.001	0.999	0.000
S51.0 Open wound of elbow	0.001	0.999	0.000
L27 Dermatitis due to substances taken internally	0.001	0.999	0.000
S59 Other and unspecified injuries of forearm	0.001	0.999	0.000
S58 Traumatic amputation of forearm	0.001	0.999	0.000
S57 Crushing injury of forearm	0.001	0.999	0.000
S55 Injury of blood vessels at forearm level	0.001	0.999	0.000
S54 Injury of nerves at forearm level	0.001	0.999	0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.001	0.999	0.000
S99 Other and unspecified injuries of ankle and foot	0.001	0.999	0.000
S52.21 Fracture of shaft of ulna (open)	0.001	0.999	0.000
S52.20 Fracture of shaft of ulna (closed)	0.001	0.999	0.000
S52.31 Fracture of shaft of radius (open)	0.001	0.999	0.000
S52.30 Fracture of shaft of radius (closed)	0.001	0.999	0.000
S52.41 Fracture of shafts of both ulna and radius (open)	0.001	0.999	0.000
S52.40 Fracture of shafts of both ulna and radius (closed)	0.001	0.999	0.000
S52.71 Multiple fractures of forearm (open)	0.001	0.999	0.000
S52.70 Multiple fractures of forearm (closed)	0.001	0.999	0.000
S52.81 Fracture of other parts of forearm (open)	0.001	0.999	0.000
S52.80 Fracture of other parts of forearm (closed)	0.001	0.999	0.000
S52.91 Fracture of forearm, part unspecified (open)	0.001	0.999	0.000
S52.90 Fracture of forearm, part unspecified (closed)	0.001	0.999	0.000
F06.7 Mild cognitive disorder	0.001	0.999	0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.000	0.999	0.001
S99.9 Unspecified injury of ankle and foot	0.001	0.999	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.001	0.999	0.000
S42.71 Multiple fractures of clavicle, scapula and humerus (open)	0.001	0.999	0.000
S42.70 Multiple fractures of clavicle, scapula and humerus (closed)	0.001	0.999	0.000
S42.81 Fracture of other parts of shoulder and upper arm (open)	0.001	0.999	0.000
S42.80 Fracture of other parts of shoulder and upper arm (closed)	0.001	0.999	0.000
S42.91 Fracture of shoulder girdle, part unspecified (open)	0.001	0.999	0.000
S42.90 Fracture of shoulder girdle, part unspecified (closed)	0.001	0.999	0.000
L85.8 Other specified epidermal thickening	0.001	0.999	0.000
M49.8 Spondylopathy in other diseases classified elsewhere	0.000	0.999	0.001
M49.5 Collapsed vertebra in diseases classified elsewhere	0.000	0.999	0.001
M49.4 Neuropathic spondylopathy	0.000	0.999	0.001
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere	0.000	0.999	0.001
M49.2 Enterobacterial spondylitis	0.000	0.999	0.001
M49.1 Brucella spondylitis	0.000	0.999	0.001
M49.0 Tuberculosis of spine	0.000	0.999	0.001
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.000	0.999	0.001
S91.1 Open wound of toe(s) without damage to nail	0.001	0.999	0.000
S92.5 Fracture of other toe	0.001	0.999	0.000
K45 Other abdominal hernia	0.000	0.999	0.001
Q78 Other osteochondrodysplasias	0.001	0.999	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.001	0.999	0.000
Q76 Congenital malformations of spine and bony thorax	0.001	0.999	0.000
Q75 Other congenital malformations of skull and face bones	0.001	0.999	0.000
Q74 Other congenital malformations of limb(s)	0.001	0.999	0.000
Q73 Reduction defects of unspecified limb	0.001	0.999	0.000
Q72 Reduction defects of lower limb	0.001	0.999	0.000
Q71 Reduction defects of upper limb	0.001	0.999	0.000
Q70 Syndactyly	0.001	0.999	0.000
Q69 Polydactyly	0.001	0.999	0.000
Q68 Other congenital musculoskeletal deformities	0.001	0.999	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.001	0.999	0.000
Q66 Congenital deformities of feet	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations