TreeWAS – Variant ID: rs6901541

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.000	1.000
D64.9 Anaemia, unspecified	1.000	0.000	0.000
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
E05.0 Thyrotoxicosis with diffuse goitre	1.000	0.000	0.000
E10.9 Without complications	1.000	0.000	0.000
E10.3 With ophthalmic complications	1.000	0.000	0.000
K90.0 Coeliac disease	1.000	0.000	0.000
M06.9 Rheumatoid arthritis, unspecified	0.000	0.000	1.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
R31 Unspecified haematuria	0.000	0.000	1.000
E20-E35 Disorders of other endocrine glands	1.000	0.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.000	1.000
E03 Other hypothyroidism	1.000	0.000	0.000
M06 Other rheumatoid arthritis	0.000	0.000	1.000
D64 Other anaemias	1.000	0.000	0.000
D60-D64 Aplastic and other anaemias	1.000	0.000	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	1.000	0.000	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.000	1.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.000	1.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	1.000	0.000	0.000
K90 Intestinal malabsorption	1.000	0.000	0.000
D69 Purpura and other haemorrhagic conditions	1.000	0.000	0.000
Chapter VII Diseases of the eye and adnexa	1.000	0.000	0.000
M05 Seropositive rheumatoid arthritis	0.000	0.000	1.000
M05-M14 Inflammatory polyarthropathies	0.000	0.000	0.999
E10.1 With ketoacidosis	1.000	0.000	0.000
E14 Unspecified diabetes mellitus	1.000	0.000	0.000
D50-D53 Nutritional anaemias	0.999	0.001	0.000
H30-H36 Disorders of choroid and retina	0.999	0.001	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.999	0.001	0.000
I60-I69 Cerebrovascular diseases	0.999	0.001	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.998	0.002	0.000
H36 Retinal disorders in diseases classified elsewhere	0.998	0.002	0.000
D50 Iron deficiency anaemia	0.998	0.002	0.000
H36.0 Diabetic retinopathy	0.998	0.002	0.000
D50.9 Iron deficiency anaemia, unspecified	0.998	0.002	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.997	0.003	0.000
D69.6 Thrombocytopenia, unspecified	0.997	0.003	0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.997	0.003	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.997	0.003	0.000
E27 Other disorders of adrenal gland	0.997	0.003	0.000
H06.2 Dysthyroid exophthalmos	0.996	0.004	0.000
M35.0 Sicca syndrome [Sjogren]	0.995	0.005	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.995	0.005	0.000
E27.1 Primary adrenocortical insufficiency	0.995	0.005	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.995	0.005	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.995	0.005	0.000
G56.0 Carpal tunnel syndrome	0.994	0.006	0.000
N40 Hyperplasia of prostate	0.000	0.006	0.994
D80-D89 Certain disorders involving the immune mechanism	0.993	0.007	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.993	0.007	0.000
G56 Mononeuropathies of upper limb	0.993	0.007	0.000
K90.9 Intestinal malabsorption, unspecified	0.992	0.008	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.008	0.992
Q60-Q64 Congenital malformations of the urinary system	0.991	0.009	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.988	0.012	0.000
Chapter VI Diseases of the nervous system	0.987	0.013	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.987	0.013	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.987	0.013	0.000
C81 Hodgkin's disease	0.985	0.015	0.000
M35 Other systemic involvement of connective tissue	0.985	0.015	0.000
E14.3 With ophthalmic complications	0.982	0.018	0.000
M20-M25 Other joint disorders	0.980	0.020	0.000
K90-K93 Other diseases of the digestive system	0.980	0.020	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.979	0.021	0.000
Chapter XI Diseases of the digestive system	0.979	0.021	0.000
E14.9 Without complications	0.979	0.021	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.978	0.022	0.000
D86 Sarcoidosis	0.978	0.022	0.000
E16 Other disorders of pancreatic internal secretion	0.977	0.023	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.974	0.026	0.000
N00-N08 Glomerular diseases	0.974	0.026	0.000
E21.3 Hyperparathyroidism, unspecified	0.974	0.026	0.000
M15-M19 Arthrosis	0.972	0.028	0.000
E10.2 With renal complications	0.971	0.029	0.000
E21.0 Primary hyperparathyroidism	0.969	0.031	0.000
N04 Nephrotic syndrome	0.968	0.032	0.000
E16.2 Hypoglycaemia, unspecified	0.968	0.032	0.000
K70-K77 Diseases of liver	0.967	0.033	0.000
C91 Lymphoid leukaemia	0.966	0.034	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.035	0.965
N08 Glomerular disorders in diseases classified elsewhere	0.964	0.036	0.000
N05 Unspecified nephritic syndrome	0.960	0.040	0.000
H05 Disorders of orbit	0.957	0.043	0.000
M06.3 Rheumatoid nodule	0.000	0.043	0.957
N04.9 Unspecified	0.957	0.043	0.000
D69.4 Other primary thrombocytopenia	0.956	0.044	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.955	0.045	0.000
I73 Other peripheral vascular diseases	0.953	0.047	0.000
Q61 Cystic kidney disease	0.952	0.048	0.000
M18 Arthrosis of first carpometacarpal joint	0.952	0.048	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.952	0.048	0.000
K75 Other inflammatory liver diseases	0.951	0.049	0.000
N08.3 Glomerular disorders in diabetes mellitus	0.950	0.050	0.000
C85.1 B-cell lymphoma, unspecified	0.949	0.051	0.000
C83.3 Large cell (diffuse)	0.948	0.052	0.000
K75.4 Autoimmune hepatitis	0.944	0.056	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.944	0.056	0.000
I63 Cerebral infarction	0.941	0.059	0.000
E10.4 With neurological complications	0.941	0.059	0.000
I10-I15 Hypertensive diseases	0.941	0.059	0.000
D51 Vitamin B12 deficiency anaemia	0.939	0.061	0.000
D86.9 Sarcoidosis, unspecified	0.938	0.062	0.000
C81.9 Hodgkin's disease, unspecified	0.936	0.064	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.064	0.936
H35 Other retinal disorders	0.935	0.065	0.000
Q43 Other congenital malformations of intestine	0.929	0.071	0.000
I12 Hypertensive renal disease	0.928	0.072	0.000
G51 Facial nerve disorders	0.928	0.072	0.000
M06.34 Rheumatoid nodule (Hand)	0.000	0.074	0.926
M60-M63 Disorders of muscles	0.925	0.075	0.000
Q61.3 Polycystic kidney, unspecified	0.920	0.080	0.000
L10-L14 Bullous disorders	0.919	0.081	0.000
M17 Gonarthrosis [arthrosis of knee]	0.919	0.081	0.000
M17.1 Other primary gonarthrosis	0.918	0.082	0.000
Chapter XIV Diseases of the genitourinary system	0.915	0.085	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.914	0.086	0.000
C91.1 Chronic lymphocytic leukaemia	0.913	0.087	0.000
H05.2 Exophthalmic conditions	0.911	0.089	0.000
K73 Chronic hepatitis, not elsewhere classified	0.908	0.092	0.000
D55-D59 Haemolytic anaemias	0.901	0.099	0.000
M07 Psoriatic and enteropathic arthropathies	0.000	0.100	0.900
I62 Other nontraumatic intracranial haemorrhage	0.900	0.100	0.000
M32 Systemic lupus erythematosus	0.899	0.101	0.000
N05.1 Focal and segmental glomerular lesions	0.899	0.101	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.896	0.104	0.000
D68 Other coagulation defects	0.896	0.104	0.000
N05.2 Diffuse membranous glomerulonephritis	0.894	0.106	0.000
L13 Other bullous disorders	0.892	0.108	0.000
Q44.6 Cystic disease of liver	0.892	0.108	0.000
I73.0 Raynaud's syndrome	0.891	0.109	0.000
N17-N19 Renal failure	0.889	0.111	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.889	0.111	0.000
M15 Polyarthrosis	0.888	0.112	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.888	0.112	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.887	0.113	0.000
I20-I25 Ischaemic heart diseases	0.885	0.115	0.000
C81.1 Nodular sclerosis	0.885	0.115	0.000
N18 Chronic renal failure	0.885	0.115	0.000
M34 Systemic sclerosis	0.883	0.117	0.000
I12.9 Hypertensive renal disease without renal failure	0.883	0.117	0.000
I24 Other acute ischaemic heart diseases	0.882	0.118	0.000
E28 Ovarian dysfunction	0.882	0.118	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.881	0.119	0.000
I24.8 Other forms of acute ischaemic heart disease	0.881	0.119	0.000
Q60.0 Renal agenesis, unilateral	0.881	0.119	0.000
G51.0 Bell's palsy	0.877	0.123	0.000
E50-E64 Other nutritional deficiencies	0.876	0.124	0.000
L13.0 Dermatitis herpetiformis	0.873	0.127	0.000
I12.0 Hypertensive renal disease with renal failure	0.871	0.129	0.000
E29 Testicular dysfunction	0.871	0.129	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.868	0.132	0.000
E14.8 With unspecified complications	0.865	0.135	0.000
Q60.2 Renal agenesis, unspecified	0.863	0.137	0.000
I77 Other disorders of arteries and arterioles	0.863	0.137	0.000
D61 Other aplastic anaemias	0.863	0.137	0.000
L50-L54 Urticaria and erythema	0.862	0.138	0.000
E06 Thyroiditis	0.861	0.139	0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.860	0.140	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.854	0.146	0.000
H34 Retinal vascular occlusions	0.852	0.148	0.000
H35.2 Other proliferative retinopathy	0.851	0.149	0.000
I70 Atherosclerosis	0.851	0.149	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.851	0.149	0.000
Chapter II Neoplasms	0.849	0.151	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.153	0.847
D86.3 Sarcoidosis of skin	0.847	0.153	0.000
H35.8 Other specified retinal disorders	0.847	0.153	0.000
D80 Immunodeficiency with predominantly antibody defects	0.846	0.154	0.000
Q39 Congenital malformations of oesophagus	0.846	0.154	0.000
N18.3 Chronic kidney disease, stage 3	0.845	0.155	0.000
I74 Arterial embolism and thrombosis	0.845	0.155	0.000
E10.0 With coma	0.844	0.156	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.841	0.159	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.841	0.159	0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.841	0.159	0.000
H35.4 Peripheral retinal degeneration	0.840	0.160	0.000
G59 Mononeuropathy in diseases classified elsewhere	0.840	0.160	0.000
I73.9 Peripheral vascular disease, unspecified	0.839	0.161	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.839	0.161	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.838	0.162	0.000
M60 Myositis	0.838	0.162	0.000
C83.7 Burkitt's tumour	0.836	0.164	0.000
C91.9 Lymphoid leukaemia, unspecified	0.835	0.165	0.000
C92 Myeloid leukaemia	0.834	0.166	0.000
E10.5 With peripheral circulatory complications	0.833	0.167	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.167	0.833
E14.1 With ketoacidosis	0.831	0.169	0.000
D86.0 Sarcoidosis of lung	0.830	0.170	0.000
G58 Other mononeuropathies	0.830	0.170	0.000
M80-M85 Disorders of bone density and structure	0.829	0.171	0.000
M07.3 Other psoriatic arthropathies	0.000	0.171	0.829
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.829	0.171	0.000
M06.0 Seronegative rheumatoid arthritis	0.000	0.173	0.827
E22 Hyperfunction of pituitary gland	0.827	0.173	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.827	0.173	0.000
Chapter I Certain infectious and parasitic diseases	0.826	0.174	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.825	0.175	0.000
M35.7 Hypermobility syndrome	0.824	0.176	0.000
D68.0 Von Willebrand's disease	0.824	0.176	0.000
C88 Malignant immunoproliferative diseases	0.823	0.177	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.178	0.822
I77.1 Stricture of artery	0.822	0.178	0.000
N04.1 Focal and segmental glomerular lesions	0.821	0.179	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.821	0.179	0.000
E10.7 With multiple complications	0.820	0.180	0.000
H33 Retinal detachments and breaks	0.819	0.181	0.000
D64.8 Other specified anaemias	0.819	0.181	0.000
N08.5 Glomerular disorders in systemic connective tissue disorders	0.813	0.187	0.000
E07 Other disorders of thyroid	0.809	0.191	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.808	0.192	0.000
N18.9 Chronic renal failure, unspecified	0.807	0.193	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.806	0.194	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.195	0.805
C83.1 Small cleaved cell (diffuse)	0.805	0.195	0.000
C81.2 Mixed cellularity	0.804	0.196	0.000
H35.0 Background retinopathy and retinal vascular changes	0.804	0.196	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.802	0.198	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.802	0.198	0.000
E20 Hypoparathyroidism	0.802	0.198	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.802	0.198	0.000
E11 Non-insulin-dependent diabetes mellitus	0.798	0.202	0.000
D69.2 Other nonthrombocytopenic purpura	0.798	0.202	0.000
I63.8 Other cerebral infarction	0.798	0.202	0.000
M15.2 Bouchard's nodes (with arthropathy)	0.796	0.204	0.000
K35-K38 Diseases of appendix	0.795	0.205	0.000
C95 Leukaemia of unspecified cell type	0.794	0.206	0.000
K74 Fibrosis and cirrhosis of liver	0.792	0.208	0.000
E31 Polyglandular dysfunction	0.791	0.209	0.000
M62 Other disorders of muscle	0.790	0.210	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.788	0.211	0.000
H05.0 Acute inflammation of orbit	0.787	0.213	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.787	0.213	0.000
C84.5 Other and unspecified T-cell lymphomas	0.787	0.213	0.000
K75.8 Other specified inflammatory liver diseases	0.786	0.214	0.000
N18.4 Chronic kidney disease, stage 4	0.786	0.214	0.000
G56.4 Causalgia	0.786	0.214	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.784	0.216	0.000
I22 Subsequent myocardial infarction	0.784	0.216	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.783	0.217	0.000
H34.8 Other retinal vascular occlusions	0.782	0.218	0.000
K50-K52 Noninfective enteritis and colitis	0.777	0.218	0.005
C04 Malignant neoplasm of floor of mouth	0.782	0.218	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.780	0.220	0.000
G58.9 Mononeuropathy, unspecified	0.779	0.221	0.000
E29.1 Testicular hypofunction	0.779	0.221	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.778	0.222	0.000
M35.1 Other overlap syndromes	0.778	0.222	0.000
N04.2 Diffuse membranous glomerulonephritis	0.778	0.222	0.000
K73.9 Chronic hepatitis, unspecified	0.777	0.223	0.000
D59 Acquired haemolytic anaemia	0.777	0.223	0.000
C07 Malignant neoplasm of parotid gland	0.776	0.224	0.000
M11 Other crystal arthropathies	0.000	0.224	0.776
E23 Hypofunction and other disorders of pituitary gland	0.775	0.225	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.774	0.226	0.000
Q40 Other congenital malformations of upper alimentary tract	0.773	0.227	0.000
E27.8 Other specified disorders of adrenal gland	0.772	0.228	0.000
K72 Hepatic failure, not elsewhere classified	0.772	0.228	0.000
G51.9 Disorder of facial nerve, unspecified	0.770	0.230	0.000
E14.5 With peripheral circulatory complications	0.769	0.230	0.000
K52.8 Other specified non-infective gastro-enteritis and colitis	0.769	0.231	0.000
Q00-Q07 Congenital malformations of the nervous system	0.768	0.232	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.768	0.232	0.000
E10.8 With unspecified complications	0.767	0.233	0.000
M60.9 Myositis, unspecified	0.767	0.233	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.000	0.233	0.767
K52 Other non-infective gastro-enteritis and colitis	0.765	0.234	0.001
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.766	0.234	0.000
Q80-Q89 Other congenital malformations	0.763	0.237	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.762	0.238	0.000
M14 Arthropathies in other diseases classified elsewhere	0.000	0.238	0.762
G57 Mononeuropathies of lower limb	0.762	0.238	0.000
H33.3 Retinal breaks without detachment	0.761	0.239	0.000
E06.3 Autoimmune thyroiditis	0.760	0.240	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.240	0.760
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.759	0.241	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.759	0.241	0.000
D68.6 Other Thrombophilia	0.759	0.241	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.242	0.758
E21.2 Other hyperparathyroidism	0.758	0.242	0.000
Q43.3 Congenital malformations of intestinal fixation	0.757	0.243	0.000
G12 Spinal muscular atrophy and related syndromes	0.756	0.244	0.000
Q44.5 Other congenital malformations of bile ducts	0.756	0.244	0.000
E40-E46 Malnutrition	0.756	0.244	0.000
C84.8 Cutaneous T-cell lymphoma, unspecified	0.755	0.245	0.000
E28.2 Polycystic ovarian syndrome	0.754	0.246	0.000
Q61.9 Cystic kidney disease, unspecified	0.752	0.248	0.000
E34 Other endocrine disorders	0.752	0.248	0.000
D58 Other hereditary haemolytic anaemias	0.751	0.249	0.000
M34.8 Other forms of systemic sclerosis	0.750	0.250	0.000
N18.0 End-stage renal disease	0.750	0.250	0.000
E11.3 With ophthalmic complications	0.749	0.251	0.000
L20-L30 Dermatitis and eczema	0.749	0.251	0.000
B35-B49 Mycoses	0.749	0.251	0.000
M33 Dermatopolymyositis	0.748	0.252	0.000
Q43.0 Meckel's diverticulum	0.748	0.252	0.000
M81 Osteoporosis without pathological fracture	0.746	0.254	0.000
C81.0 Lymphocytic predominance	0.744	0.255	0.000
I15 Secondary hypertension	0.744	0.256	0.000
G56.9 Mononeuropathy of upper limb, unspecified	0.740	0.260	0.000
E14.2 Withrenal complications	0.738	0.262	0.000
G52 Disorders of other cranial nerves	0.738	0.262	0.000
K35 Acute appendicitis	0.737	0.263	0.000
B25-B34 Other viral diseases	0.736	0.264	0.000
D68.8 Other specified coagulation defects	0.736	0.264	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.735	0.265	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.734	0.265	0.000
I00-I02 Acute rheumatic fever	0.733	0.267	0.000
Q61.2 Polycystic kidney, adult type	0.731	0.269	0.000
D52 Folate deficiency anaemia	0.731	0.269	0.000
C84.0 Mycosis fungoides	0.731	0.269	0.000
G59.0 Diabetic mononeuropathy	0.731	0.269	0.000
N05.8 Other	0.730	0.270	0.000
L53 Other erythematous conditions	0.729	0.271	0.000
D61.9 Aplastic anaemia, unspecified	0.729	0.271	0.000
C91.5 Adult T-cell leukaemia	0.729	0.271	0.000
C92.0 Acute myeloid leukaemia	0.728	0.272	0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.728	0.272	0.000
K35.9 Acute appendicitis, unspecified	0.727	0.273	0.000
L08 Other local infections of skin and subcutaneous tissue	0.727	0.273	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.726	0.273	0.000
D83 Common variable immunodeficiency	0.726	0.274	0.000
Q35-Q37 Cleft lip and cleft palate	0.726	0.274	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.726	0.274	0.000
D69.9 Haemorrhagic condition, unspecified	0.725	0.275	0.000
D68.5 Primary Thrombophilia	0.724	0.276	0.000
L03 Cellulitis	0.723	0.277	0.000
Q39.9 Congenital malformation of oesophagus, unspecified	0.722	0.278	0.000
H00.1 Chalazion	0.000	0.279	0.721
N05.9 Unspecified	0.719	0.281	0.000
E28.3 Primary ovarian failure	0.717	0.283	0.000
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.717	0.283	0.000
E32 Diseases of thymus	0.717	0.283	0.000
E30 Disorders of puberty, not elsewhere classified	0.717	0.283	0.000
E25 Adrenogenital disorders	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.283	0.717
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.283	0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.283	0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.283	0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.283	0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.283	0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.283	0.717
E03.5 Myxoedema coma	0.717	0.283	0.000
E03.4 Atrophy of thyroid (acquired)	0.717	0.283	0.000
E03.3 Postinfectious hypothyroidism	0.717	0.283	0.000
E03.1 Congenital hypothyroidism without goitre	0.717	0.283	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.717	0.283	0.000
M06.8 Other specified rheumatoid arthritis	0.000	0.283	0.717
M06.2 Rheumatoid bursitis	0.000	0.283	0.717
M06.1 Adult-onset Still's disease	0.000	0.283	0.717
D64.4 Congenital dyserythropoietic anaemia	0.717	0.283	0.000
D64.3 Other sideroblastic anaemias	0.717	0.283	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.717	0.283	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.717	0.283	0.000
D64.0 Hereditary sideroblastic anaemia	0.717	0.283	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.717	0.283	0.000
D67 Hereditary factor IX deficiency	0.717	0.283	0.000
C91.0 Acute lymphoblastic leukaemia	0.717	0.283	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.717	0.283	0.000
K90.3 Pancreatic steatorrhoea	0.717	0.283	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.717	0.283	0.000
K90.1 Tropical sprue	0.717	0.283	0.000
E27.2 Addisonian crisis	0.717	0.283	0.000
D69.8 Other specified haemorrhagic conditions	0.717	0.283	0.000
D69.1 Qualitative platelet defects	0.717	0.283	0.000
M05.8 Other seropositive rheumatoid arthritis	0.000	0.283	0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.000	0.283	0.717
M05.2 Rheumatoid vasculitis	0.000	0.283	0.717
M05.1 Rheumatoid lung disease	0.000	0.283	0.717
M05.0 Felty's syndrome	0.000	0.283	0.717
M09 Juvenile arthritis in diseases classified elsewhere	0.000	0.283	0.716
M08 Juvenile arthritis	0.000	0.283	0.716
E14.7 With multiple complications	0.717	0.283	0.000
E14.0 With coma	0.717	0.283	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.717	0.283	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.716	0.284	0.000
M34.0 Progressive systemic sclerosis	0.716	0.284	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.716	0.284	0.000
C94 Other leukaemias of specified cell type	0.716	0.284	0.000
C93 Monocytic leukaemia	0.716	0.284	0.000
C86 Other specified types of T/NK-cell lymphoma	0.716	0.284	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.716	0.284	0.000
G54 Nerve root and plexus disorders	0.716	0.284	0.000
D50.1 Sideropenic dysphagia	0.715	0.285	0.000
I67 Other cerebrovascular diseases	0.715	0.285	0.000
H06.3 Other disorders of orbit in diseases classified elsewhere	0.715	0.285	0.000
H06.1 Parasitic infestation of orbit in diseases classified elsewhere	0.715	0.285	0.000
H06.0 Disorders of lachrymal system in diseases classified elsewhere	0.715	0.285	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.714	0.285	0.000
E21.4 Other specified disorders of parathyroid gland	0.714	0.285	0.000
E27.5 Adrenomedullary hyperfunction	0.714	0.285	0.000
E27.0 Other adrenocortical overactivity	0.714	0.285	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.714	0.286	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.714	0.286	0.000
Q45 Other congenital malformations of digestive system	0.713	0.287	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.713	0.287	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.713	0.287	0.000
G14 Postpolio syndrome	0.713	0.287	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.713	0.287	0.000
C85.0 Lymphosarcoma	0.713	0.287	0.000
D86.8 Sarcoidosis of other and combined sites	0.713	0.287	0.000
C04.9 Floor of mouth, unspecified	0.713	0.287	0.000
D81 Combined immunodeficiencies	0.712	0.288	0.000
E03.8 Other specified hypothyroidism	0.712	0.288	0.000
H30 Chorioretinal inflammation	0.711	0.289	0.000
H03 Disorders of eyelid in diseases classified elsewhere	0.711	0.289	0.000
L52 Erythema nodosum	0.711	0.289	0.000
K90.8 Other intestinal malabsorption	0.711	0.289	0.000
E14.4 With neurological complications	0.710	0.290	0.000
B15-B19 Viral hepatitis	0.709	0.291	0.000
I79.1 Aortitis in diseases classified elsewhere	0.709	0.291	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.709	0.291	0.000
G70-G73 Diseases of myoneural junction and muscle	0.708	0.292	0.000
E15 Nondiabetic hypoglycaemic coma	0.707	0.293	0.000
D82 Immunodeficiency associated with other major defects	0.707	0.293	0.000
L03.1 Cellulitis of other parts of limb	0.707	0.293	0.000
C81.7 Other Hodgkin's disease	0.706	0.294	0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.706	0.294	0.000
C81.3 Lymphocytic depletion	0.706	0.294	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.706	0.294	0.000
M35.8 Other specified systemic involvement of connective tissue	0.706	0.294	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.706	0.294	0.000
M35.5 Multifocal fibrosclerosis	0.706	0.294	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.706	0.294	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.706	0.294	0.000
Q43.8 Other specified congenital malformations of intestine	0.706	0.294	0.000
M06.4 Inflammatory polyarthropathy	0.000	0.294	0.705
H46-H48 Disorders of optic nerve and visual pathways	0.705	0.295	0.000
L11 Other acantholytic disorders	0.703	0.297	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.702	0.297	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.702	0.298	0.000
M15.8 Other polyarthrosis	0.702	0.298	0.000
N18.2 Chronic kidney disease, stage 2	0.702	0.298	0.000
M60.99 Myositis, unspecified (Site unspecified)	0.702	0.298	0.000
E61 Deficiency of other nutrient elements	0.701	0.299	0.000
K74.3 Primary biliary cirrhosis	0.701	0.299	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.700	0.299	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.701	0.299	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.701	0.299	0.000
E16.4 Abnormal secretion of gastrin	0.701	0.299	0.000
E16.3 Increased secretion of glucagon	0.701	0.299	0.000
E07.8 Other specified disorders of thyroid	0.699	0.301	0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified	0.698	0.302	0.000
C83.6 Undifferentiated (diffuse)	0.698	0.302	0.000
C83.5 Lymphoblastic (diffuse)	0.698	0.302	0.000
C83.4 Immunoblastic (diffuse)	0.698	0.302	0.000
C83.2 Mixed small and large cell (diffuse)	0.698	0.302	0.000
N07 Hereditary nephropathy, not elsewhere classified	0.698	0.302	0.000
N06 Isolated proteinuria with specified morphological lesion	0.698	0.302	0.000
N01 Rapidly progressive nephritic syndrome	0.698	0.302	0.000
N00 Acute nephritic syndrome	0.698	0.302	0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.697	0.303	0.000
I70.0 Atherosclerosis of aorta	0.697	0.303	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.696	0.304	0.000
E51 Thiamine deficiency	0.695	0.304	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.695	0.305	0.000
H50 Other strabismus	0.695	0.305	0.000
E53 Deficiency of other B group vitamins	0.695	0.305	0.000
N04.8 Other	0.694	0.306	0.000
N04.7 Diffuse crescentic glomerulonephritis	0.694	0.306	0.000
N04.6 Dense deposit disease	0.694	0.306	0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis	0.694	0.306	0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis	0.694	0.306	0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis	0.694	0.306	0.000
N04.0 Minor glomerular abnormality	0.694	0.306	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.693	0.307	0.000
K77 Liver disorders in diseases classified elsewhere	0.693	0.307	0.000
K71 Toxic liver disease	0.693	0.307	0.000
H05.8 Other disorders of orbit	0.693	0.307	0.000
G11 Hereditary ataxia	0.693	0.307	0.000
C91.8 Mature B-cell leukaemia Burkitt-type	0.692	0.307	0.000
C91.7 Other lymphoid leukaemia	0.692	0.307	0.000
C91.6 Prolymphocytic leukaemia of T-cell type	0.692	0.307	0.000
C91.3 Prolymphocytic leukaemia	0.692	0.307	0.000
C91.2 Subacute lymphocytic leukaemia	0.692	0.307	0.000
M15.4 Erosive (osteo)arthrosis	0.691	0.309	0.000
N08.8 Glomerular disorders in other diseases classified elsewhere	0.691	0.309	0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases	0.691	0.309	0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism	0.691	0.309	0.000
N08.1 Glomerular disorders in neoplastic diseases	0.691	0.309	0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere	0.691	0.309	0.000
N05.7 Diffuse crescentic glomerulonephritis	0.688	0.311	0.000
N05.6 Dense deposit disease	0.688	0.311	0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis	0.688	0.311	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations