TreeWAS – Variant ID: rs6903896

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E10.9 Without complications	0.000	0.256	0.744
E10 Insulin-dependent diabetes mellitus	0.000	0.279	0.721
E10-E14 Diabetes mellitus	0.000	0.332	0.668
E10.3 With ophthalmic complications	0.000	0.345	0.655
E11 Non-insulin-dependent diabetes mellitus	0.000	0.350	0.650
E11.9 Without complications	0.000	0.402	0.598
E11.3 With ophthalmic complications	0.000	0.410	0.590
E10.8 With unspecified complications	0.000	0.483	0.517
E10.7 With multiple complications	0.000	0.483	0.517
E10.6 With other specified complications	0.000	0.483	0.517
E10.5 With peripheral circulatory complications	0.000	0.483	0.517
E10.4 With neurological complications	0.000	0.483	0.517
E10.2 With renal complications	0.000	0.483	0.517
E10.1 With ketoacidosis	0.000	0.483	0.517
E10.0 With coma	0.000	0.483	0.517
E11.4 With neurological complications	0.000	0.508	0.492
E14 Unspecified diabetes mellitus	0.000	0.511	0.489
E11.2 With renal complications	0.000	0.511	0.489
E12 Malnutrition-related diabetes mellitus	0.000	0.521	0.479
E11.8 With unspecified complications	0.000	0.534	0.466
E11.7 With multiple complications	0.000	0.534	0.466
E11.6 With other specified complications	0.000	0.534	0.466
E11.1 With ketoacidosis	0.000	0.534	0.466
E11.0 With coma	0.000	0.534	0.466
E11.5 With peripheral circulatory complications	0.000	0.542	0.458
E13 Other specified diabetes mellitus	0.000	0.548	0.452
E14.9 Without complications	0.000	0.630	0.370
E14.8 With unspecified complications	0.000	0.649	0.351
E14.7 With multiple complications	0.000	0.649	0.351
E14.6 With other specified complications	0.000	0.649	0.351
E14.5 With peripheral circulatory complications	0.000	0.649	0.351
E14.4 With neurological complications	0.000	0.649	0.351
E14.2 Withrenal complications	0.000	0.649	0.351
E14.1 With ketoacidosis	0.000	0.649	0.351
E14.0 With coma	0.000	0.649	0.351
E12.9 Without complications	0.000	0.656	0.344
E12.8 With unspecified complications	0.000	0.656	0.344
E12.7 With multiple complications	0.000	0.656	0.344
E12.6 With other specified complications	0.000	0.656	0.344
E12.5 With peripheral circulatory complications	0.000	0.656	0.344
E12.4 With neurological complications	0.000	0.656	0.344
E12.3 With ophthalmic complications	0.000	0.656	0.344
E12.2 With renal complications	0.000	0.656	0.344
E12.1 With ketoacidosis	0.000	0.656	0.344
E12.0 With coma	0.000	0.656	0.344
E14.3 With ophthalmic complications	0.000	0.660	0.340
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.676	0.324
E13.8 With unspecified complications	0.000	0.676	0.324
E13.7 With multiple complications	0.000	0.676	0.324
E13.6 With other specified complications	0.000	0.676	0.324
E13.5 With peripheral circulatory complications	0.000	0.676	0.324
E13.4 With neurological complications	0.000	0.676	0.324
E13.3 With ophthalmic complications	0.000	0.676	0.324
E13.2 With renal complications	0.000	0.676	0.324
E13.1 With ketoacidosis	0.000	0.676	0.324
E13.0 With coma	0.000	0.676	0.324
E13.9 Without complications	0.000	0.704	0.296
E50-E64 Other nutritional deficiencies	0.000	0.718	0.282
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.721	0.279
E00-E07 Disorders of thyroid gland	0.000	0.745	0.255
E16 Other disorders of pancreatic internal secretion	0.000	0.753	0.247
E40-E46 Malnutrition	0.000	0.767	0.233
E16.2 Hypoglycaemia, unspecified	0.000	0.768	0.232
E55 Vitamin D deficiency	0.000	0.773	0.227
E61 Deficiency of other nutrient elements	0.000	0.777	0.223
E53 Deficiency of other B group vitamins	0.000	0.778	0.222
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.794	0.206
E04 Other non-toxic goitre	0.000	0.797	0.203
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.798	0.202
E63 Other nutritional deficiencies	0.000	0.798	0.202
E56 Other vitamin deficiencies	0.000	0.798	0.202
E51 Thiamine deficiency	0.000	0.798	0.202
E50 Vitamin A deficiency	0.000	0.798	0.202
E60 Dietary zinc deficiency	0.000	0.798	0.202
E59 Dietary selenium deficiency	0.000	0.798	0.202
E58 Dietary calcium deficiency	0.000	0.798	0.202
E54 Ascorbic acid deficiency	0.000	0.798	0.202
E52 Niacin deficiency [pellagra]	0.000	0.798	0.202
E06 Thyroiditis	0.000	0.798	0.202
E15 Nondiabetic hypoglycaemic coma	0.000	0.799	0.200
E65-E68 Obesity and other hyperalimentation	0.000	0.803	0.197
E07 Other disorders of thyroid	0.000	0.809	0.191
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.812	0.188
E55.9 Vitamin D deficiency, unspecified	0.000	0.813	0.187
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.817	0.183
E00 Congenital iodine-deficiency syndrome	0.000	0.817	0.183
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.817	0.183
E61.1 Iron deficiency	0.000	0.819	0.181
E53.8 Deficiency of other specified B group vitamins	0.000	0.820	0.179
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.822	0.177
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.822	0.177
E16.4 Abnormal secretion of gastrin	0.000	0.822	0.177
E16.3 Increased secretion of glucagon	0.000	0.822	0.177
E16.1 Other hypoglycaemia	0.000	0.822	0.177
E46 Unspecified protein-energy malnutrition	0.000	0.833	0.167
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.833	0.167
E45 Retarded development following protein-energy malnutrition	0.000	0.833	0.167
E43 Unspecified severe protein-energy malnutrition	0.000	0.833	0.167
E42 Marasmic kwashiorkor	0.000	0.833	0.167
E41 Nutritional marasmus	0.000	0.833	0.167
E40 Kwashiorkor	0.000	0.833	0.167
E70-E90 Metabolic disorders	0.000	0.836	0.164
E06.3 Autoimmune thyroiditis	0.000	0.836	0.164
E55.0 Rickets, active	0.000	0.837	0.163
E04.2 Non-toxic multinodular goitre	0.000	0.839	0.161
E61.9 Deficiency of nutrient element, unspecified	0.000	0.840	0.160
E61.8 Deficiency of other specified nutrient elements	0.000	0.840	0.160
E61.7 Deficiency of multiple nutrient elements	0.000	0.840	0.160
E61.6 Vanadium deficiency	0.000	0.840	0.160
E61.5 Molybdenum deficiency	0.000	0.840	0.160
E61.4 Chromium deficiency	0.000	0.840	0.160
E61.3 Manganese deficiency	0.000	0.840	0.160
E61.2 Magnesium deficiency	0.000	0.840	0.160
E61.0 Copper deficiency	0.000	0.840	0.160
E53.9 Vitamin B deficiency, unspecified	0.000	0.840	0.159
E53.1 Pyridoxine deficiency	0.000	0.840	0.159
E53.0 Riboflavin deficiency	0.000	0.840	0.159
E20-E35 Disorders of other endocrine glands	0.000	0.841	0.159
E04.1 Non-toxic single thyroid nodule	0.000	0.843	0.157
E05.8 Other thyrotoxicosis	0.000	0.852	0.148
E05.5 Thyroid crisis or storm	0.000	0.852	0.148
E05.4 Thyrotoxicosis factitia	0.000	0.852	0.148
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.852	0.148
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.852	0.148
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.854	0.146
E04.8 Other specified non-toxic goitre	0.000	0.854	0.146
E04.0 Non-toxic diffuse goitre	0.000	0.854	0.146
E07.9 Disorder of thyroid, unspecified	0.000	0.855	0.145
E50.9 Vitamin A deficiency, unspecified	0.000	0.855	0.145
E50.8 Other manifestations of vitamin A deficiency	0.000	0.855	0.145
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.855	0.145
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.855	0.145
E50.5 Vitamin A deficiency with night blindness	0.000	0.855	0.145
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.855	0.145
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.855	0.145
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.855	0.145
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.855	0.145
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.855	0.145
E51.9 Thiamine deficiency, unspecified	0.000	0.855	0.145
E51.8 Other manifestations of thiamine deficiency	0.000	0.855	0.145
E51.2 Wernicke's encephalopathy	0.000	0.855	0.145
E51.1 Beriberi	0.000	0.855	0.145
E56.9 Vitamin deficiency, unspecified	0.000	0.855	0.145
E56.8 Deficiency of other vitamins	0.000	0.855	0.145
E56.1 Deficiency of vitamin K	0.000	0.855	0.145
E56.0 Deficiency of vitamin E	0.000	0.855	0.145
E63.9 Nutritional deficiency, unspecified	0.000	0.855	0.145
E63.8 Other specified nutritional deficiencies	0.000	0.855	0.145
E63.1 Imbalance of constituents of food intake	0.000	0.855	0.145
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.855	0.145
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.855	0.145
E64.8 Sequelae of other nutritional deficiencies	0.000	0.855	0.145
E64.3 Sequelae of rickets	0.000	0.855	0.145
E64.2 Sequelae of vitamin C deficiency	0.000	0.855	0.145
E64.1 Sequelae of vitamin A deficiency	0.000	0.855	0.145
E64.0 Sequelae of protein-energy malnutrition	0.000	0.855	0.145
E06.9 Thyroiditis, unspecified	0.000	0.855	0.145
E06.5 Other chronic thyroiditis	0.000	0.855	0.145
E06.4 Drug-induced thyroiditis	0.000	0.855	0.145
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.855	0.145
E06.1 Subacute thyroiditis	0.000	0.855	0.145
E06.0 Acute thyroiditis	0.000	0.855	0.145
E86 Volume depletion	0.000	0.855	0.145
E67 Other hyperalimentation	0.000	0.858	0.141
E68 Sequelae of hyperalimentation	0.000	0.858	0.141
E65 Localised adiposity	0.000	0.858	0.141
E04.9 Non-toxic goitre, unspecified	0.000	0.859	0.141
E07.8 Other specified disorders of thyroid	0.000	0.863	0.137
E07.1 Dyshormogenetic goitre	0.000	0.863	0.137
E07.0 Hypersecretion of calcitonin	0.000	0.863	0.137
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.869	0.131
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.869	0.131
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.869	0.131
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.869	0.131
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.869	0.131
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.869	0.131
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.869	0.131
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.869	0.131
E88 Other metabolic disorders	0.000	0.869	0.131
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.869	0.131
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.878	0.122
E44.1 Mild protein-energy malnutrition	0.000	0.880	0.120
E44.0 Moderate protein-energy malnutrition	0.000	0.880	0.120
E22 Hyperfunction of pituitary gland	0.000	0.881	0.118
E05.9 Thyrotoxicosis, unspecified	0.000	0.882	0.118
E85 Amyloidosis	0.000	0.882	0.118
E84 Cystic fibrosis	0.000	0.882	0.118
E79 Disorders of purine and pyrimidine metabolism	0.000	0.882	0.118
E77 Disorders of glycoprotein metabolism	0.000	0.882	0.118
E76 Disorders of glycosaminoglycan metabolism	0.000	0.882	0.118
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.882	0.118
E74 Other disorders of carbohydrate metabolism	0.000	0.882	0.118
E73 Lactose intolerance	0.000	0.882	0.118
E72 Other disorders of amino-acid metabolism	0.000	0.882	0.118
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.882	0.118
E70 Disorders of aromatic amino-acid metabolism	0.000	0.882	0.118
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.882	0.118
E83 Disorders of mineral metabolism	0.000	0.884	0.116
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.886	0.114
E34 Other endocrine disorders	0.000	0.886	0.114
E32 Diseases of thymus	0.000	0.886	0.114
E31 Polyglandular dysfunction	0.000	0.886	0.114
E30 Disorders of puberty, not elsewhere classified	0.000	0.886	0.114
E25 Adrenogenital disorders	0.000	0.886	0.114
E20 Hypoparathyroidism	0.000	0.886	0.114
E27 Other disorders of adrenal gland	0.000	0.886	0.113
E28 Ovarian dysfunction	0.000	0.890	0.109
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.892	0.108
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.892	0.108
E24 Cushing's syndrome	0.000	0.893	0.106
E66 Obesity	0.000	0.894	0.106
E29 Testicular dysfunction	0.000	0.895	0.105
E23 Hypofunction and other disorders of pituitary gland	0.000	0.895	0.105
E67.8 Other specified hyperalimentation	0.000	0.898	0.101
E67.3 Hypervitaminosis D	0.000	0.898	0.101
E67.2 Megavitamin-B6 syndrome	0.000	0.898	0.101
E67.1 Hypercarotenaemia	0.000	0.898	0.101
E67.0 Hypervitaminosis A	0.000	0.898	0.101
E03 Other hypothyroidism	0.000	0.900	0.099
E26 Hyperaldosteronism	0.000	0.903	0.096
E88.9 Metabolic disorder, unspecified	0.000	0.906	0.094
E88.8 Other specified metabolic disorders	0.000	0.906	0.094
E88.3 Tumour lysis syndrome	0.000	0.906	0.094
E88.2 Lipomatosis, not elsewhere classified	0.000	0.906	0.094
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.906	0.094
E83.1 Disorders of iron metabolism	0.000	0.907	0.093
E80.4 Gilbert's syndrome	0.000	0.907	0.093
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.909	0.091
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.910	0.089
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.912	0.088
E80.6 Other disorders of bilirubin metabolism	0.000	0.912	0.088
E80.5 Crigler-Najjar syndrome	0.000	0.912	0.088
E80.3 Defects of catalase and peroxydase	0.000	0.912	0.088
E80.2 Other porphyria	0.000	0.912	0.088
E80.1 Porphyria cutanea tarda	0.000	0.912	0.088
E80.0 Hereditary erythropoietic porphyria	0.000	0.912	0.088
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.915	0.085
E22.8 Other hyperfunction of pituitary gland	0.000	0.915	0.085
E22.1 Hyperprolactinaemia	0.000	0.915	0.085
E22.0 Acromegaly and pituitary gigantism	0.000	0.915	0.085
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.915	0.084
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.915	0.084
E70.3 Albinism	0.000	0.915	0.084
E70.2 Disorders of tyrosine metabolism	0.000	0.915	0.084
E70.1 Other hyperphenylalaninaemias	0.000	0.915	0.084
E70.0 Classical phenylketonuria	0.000	0.915	0.084
E71.3 Disorders of fatty-acid metabolism	0.000	0.915	0.084
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.915	0.084
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.915	0.084
E71.0 Maple-syrup-urine disease	0.000	0.915	0.084
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.915	0.084
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.915	0.084
E72.5 Disorders of glycine metabolism	0.000	0.915	0.084
E72.4 Disorders of ornithine metabolism	0.000	0.915	0.084
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.915	0.084
E72.2 Disorders of urea cycle metabolism	0.000	0.915	0.084
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.915	0.084
E72.0 Disorders of amino-acid transport	0.000	0.915	0.084
E73.9 Lactose intolerance, unspecified	0.000	0.915	0.084
E73.8 Other lactose intolerance	0.000	0.915	0.084
E73.1 Secondary lactase deficiency	0.000	0.915	0.084
E73.0 Congenital lactase deficiency	0.000	0.915	0.084
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.915	0.084
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.915	0.084
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.915	0.084
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.915	0.084
E74.2 Disorders of galactose metabolism	0.000	0.915	0.084
E74.1 Disorders of fructose metabolism	0.000	0.915	0.084
E74.0 Glycogen storage disease	0.000	0.915	0.084
E75.6 Lipid storage disorder, unspecified	0.000	0.915	0.084
E75.5 Other lipid storage disorders	0.000	0.915	0.084
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.915	0.084
E75.3 Sphingolipidosis, unspecified	0.000	0.915	0.084
E75.2 Other sphingolipidosis	0.000	0.915	0.084
E75.1 Other gangliosidosis	0.000	0.915	0.084
E75.0 GM2 gangliosidosis	0.000	0.915	0.084
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.915	0.084
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.915	0.084
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.915	0.084
E76.2 Other mucopolysaccharidoses	0.000	0.915	0.084
E76.1 Mucopolysaccharidosis, type II	0.000	0.915	0.084
E76.0 Mucopolysaccharidosis, type I	0.000	0.915	0.084
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.915	0.084
E77.8 Other disorders of glycoprotein metabolism	0.000	0.915	0.084
E77.1 Defects in glycoprotein degradation	0.000	0.915	0.084
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.915	0.084
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.915	0.084
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.915	0.084
E79.1 Lesch-Nyhan syndrome	0.000	0.915	0.084
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.915	0.084
E84.9 Cystic fibrosis, unspecified	0.000	0.915	0.084
E84.8 Cystic fibrosis with other manifestations	0.000	0.915	0.084
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.915	0.084
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.915	0.084
E85.9 Amyloidosis, unspecified	0.000	0.915	0.084
E85.8 Other amyloidosis	0.000	0.915	0.084
E85.4 Organ-limited amyloidosis	0.000	0.915	0.084
E85.3 Secondary systemic amyloidosis	0.000	0.915	0.084
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.915	0.084
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.915	0.084
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.915	0.084
E83.4 Disorders of magnesium metabolism	0.000	0.915	0.085
E83.3 Disorders of phosphorus metabolism	0.000	0.917	0.083
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.917	0.083
E83.8 Other disorders of mineral metabolism	0.000	0.917	0.083
E83.2 Disorders of zinc metabolism	0.000	0.917	0.083
E83.0 Disorders of copper metabolism	0.000	0.917	0.083
E20.9 Hypoparathyroidism, unspecified	0.000	0.918	0.082
E20.8 Other hypoparathyroidism	0.000	0.918	0.082
E20.1 Pseudohypoparathyroidism	0.000	0.918	0.082
E20.0 Idiopathic hypoparathyroidism	0.000	0.918	0.082
E25.9 Adrenogenital disorder, unspecified	0.000	0.918	0.082
E25.8 Other adrenogenital disorders	0.000	0.918	0.082
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.918	0.082
E30.9 Disorder of puberty, unspecified	0.000	0.918	0.082
E30.8 Other disorders of puberty	0.000	0.918	0.082
E30.1 Precocious puberty	0.000	0.918	0.082
E30.0 Delayed puberty	0.000	0.918	0.082
E31.9 Polyglandular dysfunction, unspecified	0.000	0.918	0.082
E31.8 Other polyglandular dysfunction	0.000	0.918	0.082
E31.1 Polyglandular hyperfunction	0.000	0.918	0.082
E31.0 Autoimmune polyglandular failure	0.000	0.918	0.082
E32.9 Disease of thymus, unspecified	0.000	0.918	0.082
E32.8 Other diseases of thymus	0.000	0.918	0.082
E32.1 Abscess of thymus	0.000	0.918	0.082
E32.0 Persistent hyperplasia of thymus	0.000	0.918	0.082
E34.9 Endocrine disorder, unspecified	0.000	0.918	0.082
E34.8 Other specified endocrine disorders	0.000	0.918	0.082
E34.5 Androgen resistance syndrome	0.000	0.918	0.082
E34.4 Constitutional tall stature	0.000	0.918	0.082
E34.3 Short stature, not elsewhere classified	0.000	0.918	0.082
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.918	0.082
E34.1 Other hypersecretion of intestinal hormones	0.000	0.918	0.082
E34.0 Carcinoid syndrome	0.000	0.918	0.082
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.918	0.082
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.918	0.082
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.918	0.082
E27.9 Disorder of adrenal gland, unspecified	0.000	0.918	0.081
E27.8 Other specified disorders of adrenal gland	0.000	0.918	0.081
E27.5 Adrenomedullary hyperfunction	0.000	0.918	0.081
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.918	0.081
E27.2 Addisonian crisis	0.000	0.918	0.081
E27.1 Primary adrenocortical insufficiency	0.000	0.918	0.081
E27.0 Other adrenocortical overactivity	0.000	0.918	0.081
E66.8 Other obesity	0.000	0.919	0.081
E21.0 Primary hyperparathyroidism	0.000	0.919	0.081
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.919	0.081
E28.9 Ovarian dysfunction, unspecified	0.000	0.921	0.079
E28.8 Other ovarian dysfunction	0.000	0.921	0.079
E28.3 Primary ovarian failure	0.000	0.921	0.079
E28.1 Androgen excess	0.000	0.921	0.079
E28.0 Oestrogen excess	0.000	0.921	0.079
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.922	0.077
E21.4 Other specified disorders of parathyroid gland	0.000	0.922	0.077
E21.2 Other hyperparathyroidism	0.000	0.922	0.077
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.922	0.077
E24.8 Other Cushing's syndrome	0.000	0.923	0.076
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.923	0.076
E24.3 Ectopic ACTH syndrome	0.000	0.923	0.076
E24.2 Drug-induced Cushing's syndrome	0.000	0.923	0.076
E24.1 Nelson's syndrome	0.000	0.923	0.076
E24.0 Pituitary-dependent Cushing's disease	0.000	0.923	0.076
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.924	0.076
E66.1 Drug-induced obesity	0.000	0.924	0.076
E66.0 Obesity due to excess calories	0.000	0.924	0.076
E29.9 Testicular dysfunction, unspecified	0.000	0.924	0.075
E29.8 Other testicular dysfunction	0.000	0.924	0.075
E29.0 Testicular hyperfunction	0.000	0.924	0.075
E23.7 Disorder of pituitary gland, unspecified	0.000	0.925	0.075
E23.6 Other disorders of pituitary gland	0.000	0.925	0.075
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.925	0.075
E23.2 Diabetes insipidus	0.000	0.925	0.075
E23.1 Drug-induced hypopituitarism	0.000	0.925	0.075
E28.2 Polycystic ovarian syndrome	0.000	0.925	0.074
E03.5 Myxoedema coma	0.000	0.928	0.071
E03.4 Atrophy of thyroid (acquired)	0.000	0.928	0.071
E03.3 Postinfectious hypothyroidism	0.000	0.928	0.071
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.928	0.071
E03.1 Congenital hypothyroidism without goitre	0.000	0.928	0.071
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.928	0.071
E24.9 Cushing's syndrome, unspecified	0.000	0.930	0.069
E26.9 Hyperaldosteronism, unspecified	0.000	0.930	0.069
E26.8 Other hyperaldosteronism	0.000	0.930	0.069
E26.1 Secondary hyperaldosteronism	0.000	0.930	0.069
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.931	0.069
E29.1 Testicular hypofunction	0.000	0.933	0.067
E21.3 Hyperparathyroidism, unspecified	0.000	0.933	0.066
E23.0 Hypopituitarism	0.000	0.934	0.066
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.935	0.065
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.935	0.065
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.935	0.065
E89.5 Postprocedural testicular hypofunction	0.000	0.935	0.065
E89.4 Postprocedural ovarian failure	0.000	0.935	0.065
E89.2 Postprocedural hypoparathyroidism	0.000	0.935	0.065
E89.1 Postprocedural hypoinsulinaemia	0.000	0.935	0.065
E03.8 Other specified hypothyroidism	0.000	0.936	0.064
E83.5 Disorders of calcium metabolism	0.000	0.937	0.063
E89.3 Postprocedural hypopituitarism	0.000	0.940	0.059
E26.0 Primary hyperaldosteronism	0.001	0.948	0.051
E78.8 Other disorders of lipoprotein metabolism	0.000	0.950	0.050
E78.6 Lipoprotein deficiency	0.000	0.950	0.050
E78.4 Other hyperlipidaemia	0.000	0.950	0.050
E78.3 Hyperchylomicronaemia	0.000	0.950	0.050
E78.2 Mixed hyperlipidaemia	0.000	0.950	0.050
E78.1 Pure hyperglyceridaemia	0.000	0.950	0.050
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.950	0.049
E78.5 Hyperlipidaemia, unspecified	0.000	0.951	0.049
E89.0 Postprocedural hypothyroidism	0.000	0.952	0.048
E87 Other disorders of fluid, electrolyte and acid-base balance	0.000	0.964	0.036
E87.0 Hyperosmolality and hypernatraemia	0.000	0.971	0.029
E87.2 Acidosis	0.000	0.972	0.028
E66.9 Obesity, unspecified	0.000	0.974	0.026
E87.4 Mixed disorder of acid-base balance	0.000	0.974	0.026
E87.3 Alkalosis	0.000	0.975	0.025
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.000	0.975	0.025
E87.5 Hyperkalaemia	0.000	0.979	0.021
E87.7 Fluid overload	0.000	0.980	0.019
E87.6 Hypokalaemia	0.000	0.983	0.017
E03.9 Hypothyroidism, unspecified	0.000	0.988	0.012
D22.3 Melanocytic naevi of other and unspecified parts of face	0.000	0.991	0.009
Z87.4 Personal history of diseases of the genito-urinary system	0.000	0.992	0.008
D22 Melanocytic naevi	0.000	0.992	0.008
D22.5 Melanocytic naevi of trunk	0.000	0.992	0.008
D22.7 Melanocytic naevi of lower limb, including hip	0.000	0.993	0.007
Z87.8 Personal history of other specified conditions	0.000	0.993	0.007
D22.4 Melanocytic naevi of scalp and neck	0.000	0.994	0.006
D50.8 Other iron deficiency anaemias	0.000	0.994	0.006
E87.1 Hypo-osmolality and hyponatraemia	0.002	0.994	0.005
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue	0.000	0.994	0.006
D22.6 Melanocytic naevi of upper limb, including shoulder	0.000	0.994	0.006
Z87 Personal history of other diseases and conditions	0.000	0.994	0.006
D22.9 Melanocytic naevi, unspecified	0.000	0.994	0.006
D22.2 Melanocytic naevi of ear and external auricular canal	0.000	0.994	0.006
D22.0 Melanocytic naevi of lip	0.000	0.994	0.006
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities	0.000	0.995	0.005
D22.1 Melanocytic naevi of eyelid, including canthus	0.000	0.995	0.005
Z87.6 Personal history of certain conditions arising in the perinatal period	0.000	0.995	0.004
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium	0.000	0.995	0.004
E78.0 Pure hypercholesterolaemia	0.000	0.996	0.004
J98.4 Other disorders of lung	0.004	0.996	0.000
W19.9 Unspecified place	0.000	0.996	0.004
Y42.5 Other oestrogens and progestogens	0.000	0.996	0.004
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.996	0.004
Z87.2 Personal history of diseases of the skin and subcutaneous tissue	0.000	0.996	0.003
N80.0 Endometriosis of uterus	0.004	0.996	0.000
J98 Other respiratory disorders	0.004	0.996	0.000
J98.0 Diseases of bronchus, not elsewhere classified	0.003	0.996	0.000
M75.1 Rotator cuff syndrome	0.000	0.996	0.003
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.000	0.997	0.003
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.000	0.997	0.003
J98.8 Other specified respiratory disorders	0.003	0.997	0.000
Y43 Primarily systemic agents	0.000	0.997	0.003
D50 Iron deficiency anaemia	0.000	0.997	0.003
Y43.3 Other antineoplastic drugs	0.000	0.997	0.003
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
W19 Unspecified fall	0.000	0.997	0.003
Y45.0 Opioids and related analgesics	0.000	0.997	0.003
Y42.7 Androgens and anabolic congeners	0.000	0.997	0.003
O03.9 Complete or unspecified, without complication	0.000	0.997	0.003
J98.1 Pulmonary collapse	0.003	0.997	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.000	0.997	0.003
W19.2 School, other institution and public administrative area	0.000	0.997	0.003
I73.9 Peripheral vascular disease, unspecified	0.000	0.997	0.003
Y57 Other and unspecified drugs and medicaments	0.000	0.997	0.003
N80.9 Endometriosis, unspecified	0.003	0.997	0.000
Y42.9 Other and unspecified hormone antagonists	0.000	0.997	0.003
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.997	0.003
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.000	0.997	0.003
Y42.4 Oral contraceptives	0.000	0.997	0.003
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.997	0.003
Y42.2 Antithyroid drugs	0.000	0.997	0.003
Y42.1 Thyroid hormones and substitutes	0.000	0.997	0.003
Y42.0 Glucocorticoids and synthetic analogs	0.000	0.997	0.003
Y40 Systemic antibiotics	0.000	0.997	0.003
Z83.5 Family history of eye and ear disorders	0.003	0.997	0.000
N80 Endometriosis	0.003	0.997	0.000
J98.9 Respiratory disorder, unspecified	0.003	0.997	0.000
J98.6 Disorders of diaphragm	0.003	0.997	0.000
J98.5 Diseases of mediastinum, not elsewhere classified	0.003	0.997	0.000
J98.3 Compensatory emphysema	0.003	0.997	0.000
J98.2 Interstitial emphysema	0.003	0.997	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.997	0.003
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.000	0.997	0.003
Y45.1 Salicylates	0.000	0.997	0.003
Z87.0 Personal history of diseases of the respiratory system	0.000	0.997	0.003
Y59 Other and unspecified vaccines and biological substances	0.000	0.997	0.003
Y58 Bacterial vaccines	0.000	0.997	0.003
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.000	0.997	0.003
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.997	0.003
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.000	0.997	0.003
Y53 Agents primarily affecting the gastro-intestinal system	0.000	0.997	0.003
Y50 Central nervous system stimulants, not elsewhere classified	0.000	0.997	0.003
Y48 Anaesthetics and therapeutic gases	0.000	0.997	0.003
Y47 Sedatives, hypnotics and antianxiety drugs	0.000	0.997	0.003
Y46 Antiepileptics and anti-Parkinsonism drugs	0.000	0.997	0.003
Y83.2 Surgical operation with anastomosis, bypass or graft	0.000	0.997	0.003
N80.3 Endometriosis of pelvic peritoneum	0.003	0.997	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.000	0.997	0.003
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.000	0.997	0.003
Y45.8 Other analgesics and antipyretics	0.000	0.997	0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations