TreeWAS – Variant ID: rs6909430

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M23.30 Other meniscus derangements (Multiple sites)	0.000	0.977	0.023
M81.99 Osteoporosis, unspecified (Site unspecified)	0.016	0.984	0.000
J32.9 Chronic sinusitis, unspecified	0.012	0.988	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.012	0.988	0.000
M81.9 Osteoporosis, unspecified	0.011	0.989	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.009	0.991	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.008	0.992	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.008	0.992	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.008	0.992	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.008	0.992	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.008	0.992	0.000
Q23.1 Congenital insufficiency of aortic valve	0.000	0.993	0.007
R22.2 Localised swelling, mass and lump, trunk	0.000	0.993	0.007
J32 Chronic sinusitis	0.007	0.993	0.000
K90.0 Coeliac disease	0.007	0.993	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.006	0.994	0.000
N21.0 Calculus in bladder	0.000	0.994	0.006
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.006	0.994	0.000
C45.0 Mesothelioma of pleura	0.006	0.994	0.000
Z34.9 Supervision of normal pregnancy, unspecified	0.006	0.994	0.000
J32.0 Chronic maxillary sinusitis	0.006	0.994	0.000
J32.8 Other chronic sinusitis	0.005	0.994	0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.995	0.005
J32.4 Chronic pansinusitis	0.005	0.995	0.000
M81.98 Osteoporosis, unspecified (Other)	0.005	0.995	0.000
J32.1 Chronic frontal sinusitis	0.005	0.995	0.000
C45 Mesothelioma	0.005	0.995	0.000
J32.3 Chronic sphenoidal sinusitis	0.005	0.995	0.000
C45.7 Mesothelioma of other sites	0.005	0.995	0.000
C45.9 Mesothelioma, unspecified	0.005	0.995	0.000
Q23 Congenital malformations of aortic and mitral valves	0.000	0.995	0.005
M81 Osteoporosis without pathological fracture	0.005	0.995	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.000	0.996	0.004
M23.3 Other meniscus derangements	0.000	0.996	0.004
Q23.0 Congenital stenosis of aortic valve	0.000	0.996	0.004
S92.30 Fracture of metatarsal bone (closed)	0.004	0.996	0.000
C45.2 Mesothelioma of pericardium	0.004	0.996	0.000
C45.1 Mesothelioma of peritoneum	0.004	0.996	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.004	0.996	0.000
L89.9 Decubitus ulcer and pressure area, unspecified	0.004	0.996	0.000
K90 Intestinal malabsorption	0.004	0.996	0.000
K90.9 Intestinal malabsorption, unspecified	0.004	0.996	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.000	0.996	0.003
Q23.8 Other congenital malformations of aortic and mitral valves	0.000	0.996	0.003
Q23.4 Hypoplastic left heart syndrome	0.000	0.996	0.003
Q23.2 Congenital mitral stenosis	0.000	0.996	0.003
M81.6 Localised osteoporosis [Lequesne]	0.003	0.996	0.000
M81.5 Idiopathic osteoporosis	0.003	0.996	0.000
I34.1 Mitral (valve) prolapse	0.000	0.996	0.004
J32.2 Chronic ethmoidal sinusitis	0.003	0.996	0.000
Q23.3 Congenital mitral insufficiency	0.000	0.996	0.003
M81.8 Other osteoporosis	0.003	0.996	0.000
M81.1 Postoophorectomy osteoporosis	0.003	0.997	0.000
M23.37 Other meniscus derangements-Capsular lig	0.000	0.997	0.003
L89.1 Stage II decubitus ulcer	0.003	0.997	0.000
H11 Other disorders of conjunctiva	0.000	0.997	0.003
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.000	0.997	0.003
M81.2 Osteoporosis of disuse	0.003	0.997	0.000
T83.3 Mechanical complication of intra-uterine contraceptive device	0.000	0.997	0.003
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.997	0.003
L89 Decubitus ulcer	0.003	0.997	0.000
H11.9 Disorder of conjunctiva, unspecified	0.000	0.997	0.003
S92.3 Fracture of metatarsal bone	0.003	0.997	0.000
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.003	0.997	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.000	0.997	0.003
M81.0 Postmenopausal osteoporosis	0.003	0.997	0.000
Z63.4 Disappearance and death of family member	0.003	0.997	0.000
M81.4 Drug-induced osteoporosis	0.003	0.997	0.000
Z34 Supervision of normal pregnancy	0.003	0.997	0.000
N21 Calculus of lower urinary tract	0.000	0.997	0.003
H11.0 Pterygium	0.000	0.997	0.003
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.003	0.997	0.000
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.003	0.997	0.000
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.003	0.997	0.000
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.003	0.997	0.000
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.003	0.997	0.000
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.003	0.997	0.000
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.003	0.997	0.000
Z63 Other problems related to primary support group, including family circumstances	0.003	0.997	0.000
O63.1 Prolonged second stage (of labour)	0.003	0.997	0.000
K90.3 Pancreatic steatorrhoea	0.003	0.997	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.003	0.997	0.000
K90.1 Tropical sprue	0.003	0.997	0.000
R22.0 Localised swelling, mass and lump, head	0.000	0.997	0.003
K90.8 Other intestinal malabsorption	0.003	0.997	0.000
R27.0 Ataxia, unspecified	0.000	0.997	0.003
Z63.7 Other stressful life events affecting family and household	0.003	0.997	0.000
L97 Ulcer of lower limb, not elsewhere classified	0.000	0.997	0.003
L89.2 Stage III decubitus ulcer	0.003	0.997	0.000
M81.59 Idiopathic osteoporosis (Site unspecified)	0.003	0.997	0.000
M81.58 Idiopathic osteoporosis (Other)	0.003	0.997	0.000
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.56 Idiopathic osteoporosis (Lower leg)	0.003	0.997	0.000
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.54 Idiopathic osteoporosis (Hand)	0.003	0.997	0.000
M81.53 Idiopathic osteoporosis (Forearm)	0.003	0.997	0.000
M81.52 Idiopathic osteoporosis (Upper arm)	0.003	0.997	0.000
M81.51 Idiopathic osteoporosis (Shoulder region)	0.003	0.997	0.000
M81.50 Idiopathic osteoporosis (Multiple sites)	0.003	0.997	0.000
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.003	0.997	0.000
M81.68 Localized osteoporosis [Lequesne] (Other)	0.003	0.997	0.000
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.003	0.997	0.000
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.003	0.997	0.000
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.003	0.997	0.000
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.003	0.997	0.000
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.003	0.997	0.000
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.003	0.997	0.000
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.003	0.997	0.000
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.003	0.997	0.000
H11.2 Conjunctival scars	0.000	0.997	0.003
Z63.6 Dependent relative needing care at home	0.003	0.997	0.000
O42.9 Premature rupture of membranes, unspecified	0.000	0.997	0.003
M81.88 Other osteoporosis (Other)	0.003	0.997	0.000
M81.87 Other osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.86 Other osteoporosis (Lower leg)	0.003	0.997	0.000
M81.85 Other osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.84 Other osteoporosis (Hand)	0.003	0.997	0.000
M81.83 Other osteoporosis (Forearm)	0.003	0.997	0.000
M81.82 Other osteoporosis (Upper arm)	0.003	0.997	0.000
M81.81 Other osteoporosis (Shoulder region)	0.003	0.997	0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.000	0.997	0.003
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.002	0.997	0.000
M81.18 Postoophorectomy osteoporosis (Other)	0.002	0.997	0.000
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.002	0.997	0.000
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.002	0.997	0.000
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.002	0.997	0.000
M81.14 Postoophorectomy osteoporosis (Hand)	0.002	0.997	0.000
M81.13 Postoophorectomy osteoporosis (Forearm)	0.002	0.997	0.000
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.002	0.997	0.000
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.002	0.997	0.000
M81.80 Other osteoporosis (Multiple sites)	0.002	0.997	0.000
H11.3 Conjunctival haemorrhage	0.000	0.997	0.003
L89.3 Stage IV decubitus ulcer	0.003	0.997	0.000
S91.3 Open wound of other parts of foot	0.003	0.997	0.000
M81.89 Other osteoporosis (Site unspecified)	0.002	0.997	0.000
H11.1 Conjunctival degenerations and deposits	0.000	0.997	0.003
M50.3 Other cervical disk degeneration	0.000	0.997	0.003
S92 Fracture of foot, except ankle	0.003	0.997	0.000
S91 Open wound of ankle and foot	0.003	0.997	0.000
I34.0 Mitral (valve) insufficiency	0.000	0.997	0.003
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.997	0.002
M81.29 Osteoporosis of disuse (Site unspecified)	0.002	0.997	0.000
M81.28 Osteoporosis of disuse (Other)	0.002	0.997	0.000
M81.27 Osteoporosis of disuse (Ankle and foot)	0.002	0.997	0.000
M81.26 Osteoporosis of disuse (Lower leg)	0.002	0.997	0.000
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.002	0.997	0.000
M81.24 Osteoporosis of disuse (Hand)	0.002	0.997	0.000
M81.23 Osteoporosis of disuse (Forearm)	0.002	0.997	0.000
M81.22 Osteoporosis of disuse (Upper arm)	0.002	0.997	0.000
M81.21 Osteoporosis of disuse (Shoulder region)	0.002	0.997	0.000
H50.1 Divergent concomitant strabismus	0.000	0.997	0.003
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.002	0.997	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.003	0.997	0.000
Z63.0 Problems in relationship with spouse or partner	0.003	0.997	0.000
S92.31 Fracture of metatarsal bone (open)	0.002	0.997	0.000
N21.1 Calculus in urethra	0.000	0.997	0.002
N21.9 Calculus of lower urinary tract, unspecified	0.000	0.997	0.002
M81.08 Postmenopausal osteoporosis (Other)	0.002	0.997	0.000
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.002	0.997	0.000
M81.06 Postmenopausal osteoporosis (Lower leg)	0.002	0.997	0.000
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.002	0.997	0.000
M81.04 Postmenopausal osteoporosis (Hand)	0.002	0.997	0.000
M81.03 Postmenopausal osteoporosis (Forearm)	0.002	0.997	0.000
M81.02 Postmenopausal osteoporosis (Upper arm)	0.002	0.997	0.000
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.002	0.997	0.000
L89.0 Stage I decubitus ulcer and pressure area	0.002	0.997	0.000
S92.5 Fracture of other toe	0.002	0.997	0.000
S90 Superficial injury of ankle and foot	0.003	0.997	0.000
M81.48 Drug-induced osteoporosis (Other)	0.002	0.997	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.002	0.997	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.002	0.997	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.002	0.997	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.002	0.997	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.002	0.997	0.000
M81.42 Drug-induced osteoporosis (Upper arm)	0.002	0.997	0.000
M81.41 Drug-induced osteoporosis (Shoulder region)	0.002	0.997	0.000
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.002	0.997	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.002	0.997	0.000
S90-S99 Injuries to the ankle and foot	0.002	0.998	0.000
N13.7 Vesicoureteral-reflux-associated uropathy	0.000	0.998	0.002
I34 Nonrheumatic mitral valve disorders	0.000	0.998	0.002
Z63.9 Problem related to primary support group, unspecified	0.002	0.998	0.000
Z63.3 Absence of family member	0.002	0.998	0.000
Z63.2 Inadequate family support	0.002	0.998	0.000
Z63.1 Problems in relationship with parents and in-laws	0.002	0.998	0.000
N13 Obstructive and reflux uropathy	0.000	0.998	0.002
M80-M85 Disorders of bone density and structure	0.002	0.998	0.000
H11.8 Other specified disorders of conjunctiva	0.000	0.998	0.002
S92.50 Fracture of other toe (closed)	0.002	0.998	0.000
M81.20 Osteoporosis of disuse (Multiple sites)	0.002	0.998	0.000
K22.9 Disease of oesophagus, unspecified	0.002	0.998	0.000
Z63.8 Other specified problems related to primary support group	0.002	0.998	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.002	0.998	0.000
M81.49 Drug-induced osteoporosis (Site unspecified)	0.002	0.998	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.000	0.998	0.002
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.002	0.998	0.000
S90.3 Contusion of other and unspecified parts of foot	0.002	0.998	0.000
S92.9 Fracture of foot, unspecified	0.002	0.998	0.000
N21.8 Other lower urinary tract calculus	0.000	0.998	0.002
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
D07.5 Prostate	0.000	0.998	0.002
I34.2 Nonrheumatic mitral (valve) stenosis	0.000	0.998	0.002
Z34.0 Supervision of normal first pregnancy	0.002	0.998	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.002	0.998	0.000
S92.51 Fracture of other toe (open)	0.002	0.998	0.000
S91.2 Open wound of toe(s) with damage to nail	0.002	0.998	0.000
S91.0 Open wound of ankle	0.002	0.998	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.002	0.998	0.000
N13.8 Other obstructive and reflux uropathy	0.000	0.998	0.002
S91.1 Open wound of toe(s) without damage to nail	0.002	0.998	0.000
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.002	0.998	0.001
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.000	0.998	0.002
S91.7 Multiple open wounds of ankle and foot	0.002	0.998	0.000
S92.7 Multiple fractures of foot	0.002	0.998	0.000
S02.20 Fracture of nasal bones (closed)	0.002	0.998	0.000
K07.3 Anomalies of tooth position	0.000	0.998	0.002
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.002	0.998	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.002	0.998	0.000
M84.4 Pathological fracture, not elsewhere classified	0.002	0.998	0.000
M82 Osteoporosis in diseases classified elsewhere	0.002	0.998	0.000
Z34.8 Supervision of other normal pregnancy	0.002	0.998	0.000
M80 Osteoporosis with pathological fracture	0.002	0.998	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.002	0.998	0.000
S90.2 Contusion of toe(s) with damage to nail	0.002	0.998	0.000
S92.1 Fracture of talus	0.002	0.998	0.000
Z63.5 Disruption of family by separation and divorce	0.002	0.998	0.000
S90.1 Contusion of toe(s) without damage to nail	0.002	0.998	0.000
S92.2 Fracture of other tarsal bone(s)	0.002	0.998	0.000
M85 Other disorders of bone density and structure	0.002	0.998	0.000
S90.0 Contusion of ankle	0.002	0.998	0.000
S95 Injury of blood vessels at ankle and foot level	0.002	0.998	0.000
S94 Injury of nerves at ankle and foot level	0.002	0.998	0.000
S92.90 Fracture of foot, unspecified (closed)	0.002	0.998	0.000
N13.6 Pyonephrosis	0.000	0.998	0.002
S96.8 Injury of other muscles and tendons at ankle and foot level	0.002	0.998	0.000
Z32.1 Pregnancy confirmed	0.002	0.998	0.000
Z39.0 Care and examination immediately after delivery	0.002	0.998	0.000
S93.0 Dislocation of ankle joint	0.002	0.998	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.002	0.998	0.000
Z31.0 Tuboplasty or vasoplasty after previous sterilisation	0.002	0.998	0.000
S97 Crushing injury of ankle and foot	0.002	0.998	0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
C80.9 Malignant neoplasm, unspecified	0.000	0.998	0.002
I34.8 Other nonrheumatic mitral valve disorders	0.000	0.998	0.002
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.002	0.998	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.002	0.998	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.002	0.998	0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.000	0.998	0.002
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.002	0.998	0.000
M82.1 Osteoporosis in endocrine disorders	0.002	0.998	0.000
S90.8 Other superficial injuries of ankle and foot	0.002	0.998	0.000
S98 Traumatic amputation of ankle and foot	0.002	0.998	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
S92.91 Fracture of foot, unspecified (open)	0.002	0.998	0.000
S92.4 Fracture of great toe	0.002	0.998	0.000
S93.1 Dislocation of toe(s)	0.002	0.998	0.000
S99 Other and unspecified injuries of ankle and foot	0.002	0.998	0.000
Z58 Problems related to physical environment	0.002	0.998	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
O63.9 Long labour, unspecified	0.002	0.998	0.000
Z58.1 Exposure to air pollution	0.002	0.998	0.000
O63 Long labour	0.002	0.998	0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.002	0.998	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.000	0.998	0.002
N13.3 Other and unspecified hydronephrosis	0.000	0.998	0.002
Z33 Pregnant state, incidental	0.002	0.998	0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.002	0.998	0.000
M83 Adult osteomalacia	0.002	0.998	0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
S42.20 Fracture of upper end of humerus (closed)	0.002	0.998	0.000
S92.71 Multiple fractures of foot (open)	0.002	0.998	0.000
M85.4 Solitary bone cyst	0.002	0.998	0.000
H55 Nystagmus and other irregular eye movements	0.000	0.998	0.002
M84 Disorders of continuity of bone	0.002	0.998	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
S93.4 Sprain and strain of ankle	0.002	0.998	0.000
S93.5 Sprain and strain of toe(s)	0.002	0.998	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.002	0.998	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.002	0.998	0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.002	0.998	0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.002	0.998	0.000
M82.8 Osteoporosis in other diseases classified elsewhere	0.002	0.998	0.000
M82.0 Osteoporosis in multiple myelomatosis	0.002	0.998	0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.002	0.998	0.000
M85.8 Other specified disorders of bone density and structure	0.002	0.998	0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.002	0.998	0.000
S92.11 Fracture of talus (open)	0.002	0.998	0.000
S92.70 Multiple fractures of foot (closed)	0.002	0.998	0.000
A49.9 Bacterial infection, unspecified	0.002	0.998	0.000
H20.9 Iridocyclitis, unspecified	0.002	0.998	0.000
M80.8 Other osteoporosis with pathological fracture	0.002	0.998	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.002	0.998	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.002	0.998	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.002	0.998	0.000
M85.9 Disorder of bone density and structure, unspecified	0.002	0.998	0.000
L90.0 Lichen sclerosus et atrophicus	0.002	0.998	0.000
M85.2 Hyperostosis of skull	0.002	0.998	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.002	0.998	0.000
M85.5 Aneurysmal bone cyst	0.002	0.998	0.000
M85.3 Osteitis condensans	0.002	0.998	0.000
M85.1 Skeletal fluorosis	0.002	0.998	0.000
S92.0 Fracture of calcaneus	0.002	0.998	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.002	0.998	0.000
M89.9 Disorder of bone, unspecified	0.002	0.998	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.002	0.998	0.000
S94.8 Injury of other nerves at ankle and foot level	0.002	0.998	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.002	0.998	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.002	0.998	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.002	0.998	0.000
S94.1 Injury of medial plantar nerve	0.002	0.998	0.000
S94.0 Injury of lateral plantar nerve	0.002	0.998	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.002	0.998	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.002	0.998	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.002	0.998	0.000
S95.2 Injury of dorsal vein of foot	0.002	0.998	0.000
S95.1 Injury of plantar artery of foot	0.002	0.998	0.000
S95.0 Injury of dorsal artery of foot	0.002	0.998	0.000
Z64 Problems related to certain psychosocial circumstances	0.002	0.998	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.000	0.998	0.002
S93.3 Dislocation of other and unspecified parts of foot	0.002	0.998	0.000
Z58.8 Other problems related to physical environment	0.002	0.998	0.000
Z61 Problems related to negative life events in childhood	0.002	0.998	0.000
M85.0 Fibrous dysplasia (monostotic)	0.002	0.998	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.002	0.998	0.000
T79.6 Traumatic ischaemia of muscle	0.002	0.998	0.000
Z01.5 Diagnostic skin and sensitisation tests	0.000	0.998	0.002
M85.83 Other specified disorders of bone density and structure (Forearm)	0.002	0.998	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.002	0.998	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.002	0.998	0.000
S42.2 Fracture of upper end of humerus	0.002	0.998	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.001	0.998	0.000
S97.0 Crushing injury of ankle	0.001	0.998	0.000
M85.47 Solitary bone cyst (Ankle and foot)	0.001	0.998	0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.002	0.998	0.000
S92.10 Fracture of talus (closed)	0.001	0.998	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.002	0.998	0.000
Z64.0 Problems related to unwanted pregnancy	0.002	0.998	0.000
Z32 Pregnancy examination and test	0.002	0.998	0.000
M82.19 Osteoporosis in endocrine disorders (Site unspecified)	0.001	0.998	0.000
M82.18 Osteoporosis in endocrine disorders (Other)	0.001	0.998	0.000
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)	0.001	0.998	0.000
M82.16 Osteoporosis in endocrine disorders (Lower leg)	0.001	0.998	0.000
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)	0.001	0.998	0.000
M82.14 Osteoporosis in endocrine disorders (Hand)	0.001	0.998	0.000
M82.13 Osteoporosis in endocrine disorders (Forearm)	0.001	0.998	0.000
M82.12 Osteoporosis in endocrine disorders (Upper arm)	0.001	0.998	0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.001	0.998	0.000
K74.0 Hepatic fibrosis	0.000	0.998	0.002
S98.4 Traumatic amputation of foot, level unspecified	0.001	0.998	0.000
S98.3 Traumatic amputation of other parts of foot	0.001	0.998	0.000
S98.2 Traumatic amputation of two or more toes	0.001	0.998	0.000
S98.0 Traumatic amputation of foot at ankle level	0.001	0.998	0.000
Z58.7 Exposure to tobacco smoke	0.002	0.998	0.000
Z57 Occupational exposure to risk-factors	0.002	0.998	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.002	0.998	0.000
M85.95 Disorder of bone density and structure, unspecified (Pelvic region and thigh)	0.001	0.998	0.000
S42.90 Fracture of shoulder girdle, part unspecified (closed)	0.002	0.998	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.001	0.998	0.000
A49.1 Streptococcal infection, unspecified	0.002	0.998	0.000
M85.6 Other cyst of bone	0.002	0.998	0.000
S97.1 Crushing injury of toe(s)	0.001	0.998	0.000
S99.7 Multiple injuries of ankle and foot	0.001	0.998	0.000
Z58.9 Problem related to physical environment, unspecified	0.001	0.998	0.000
Z58.6 Inadequate drinking-water supply	0.001	0.998	0.000
Z58.4 Exposure to radiation	0.001	0.998	0.000
Z58.3 Exposure to soil pollution	0.001	0.998	0.000
Z58.2 Exposure to water pollution	0.001	0.998	0.000
Z58.0 Exposure to noise	0.001	0.998	0.000
Z65 Problems related to other psychosocial circumstances	0.002	0.998	0.000
Z60 Problems related to social environment	0.002	0.998	0.000
M85.45 Solitary bone cyst (Pelvic region and thigh)	0.001	0.998	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.002	0.998	0.000
M89.91 Disorder of bone, unspecified (Shoulder region)	0.002	0.998	0.000
N13.4 Hydroureter	0.000	0.998	0.002
O63.2 Delayed delivery of second twin, triplet, etc.	0.001	0.998	0.000
S99.9 Unspecified injury of ankle and foot	0.001	0.998	0.000
Z39 Postpartum care and examination	0.002	0.998	0.000
Z62 Other problems related to upbringing	0.002	0.998	0.000
Z55 Problems related to education and literacy	0.002	0.998	0.000
M89.96 Disorder of bone, unspecified (Lower leg)	0.002	0.998	0.000
S92.01 Fracture of calcaneus (open)	0.001	0.998	0.000
M83.9 Adult osteomalacia, unspecified	0.001	0.998	0.000
M96.0 Pseudarthrosis after fusion or arthrodesis	0.000	0.998	0.002
R20.2 Paraesthesia of skin	0.000	0.998	0.002
Z57.8 Occupational exposure to other risk-factors	0.002	0.998	0.000
M85.49 Solitary bone cyst (Site unspecified)	0.001	0.998	0.000
M85.48 Solitary bone cyst (Other)	0.001	0.998	0.000
M85.44 Solitary bone cyst (Hand)	0.001	0.998	0.000
M85.43 Solitary bone cyst (Forearm)	0.001	0.998	0.000
M85.42 Solitary bone cyst (Upper arm)	0.001	0.998	0.000
M85.41 Solitary bone cyst (Shoulder region)	0.001	0.998	0.000
M85.40 Solitary bone cyst (Multiple sites)	0.001	0.998	0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.001	0.998	0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.001	0.998	0.000
F43.2 Adjustment disorders	0.002	0.998	0.000
M83.5 Other drug-induced osteomalacia in adults	0.001	0.998	0.000
M83.4 Aluminum bone disease	0.001	0.998	0.000
M83.3 Adult osteomalacia due to malnutrition	0.001	0.998	0.000
M83.2 Adult osteomalacia due to malabsorption	0.001	0.998	0.000
M83.0 Puerperal osteomalacia	0.001	0.998	0.000
M84.9 Disorder of continuity of bone, unspecified	0.001	0.998	0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.000	0.998	0.002
S42.9 Fracture of shoulder girdle, part unspecified	0.002	0.998	0.000
M85.22 Hyperostosis of skull-Upper arm	0.001	0.998	0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.001	0.998	0.000
M85.84 Other specified disorders of bone density and structure (Hand)	0.001	0.998	0.000
M85.98 Disorder of bone density and structure, unspecified (Other)	0.001	0.998	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.001	0.998	0.000
S93.40 Sprain of unspecified ligament of ankle	0.001	0.998	0.000
M50.1 Cervical disk disorder with radiculopathy	0.000	0.998	0.002
S42.0 Fracture of clavicle	0.002	0.998	0.000
Z58.5 Exposure to other pollution	0.001	0.998	0.000
Z61.8 Other negative life events in childhood	0.001	0.998	0.000
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.001	0.998	0.000
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.001	0.998	0.000
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.001	0.998	0.000
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.001	0.998	0.000
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.001	0.998	0.000
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.001	0.998	0.000
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.001	0.998	0.000
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.001	0.998	0.000
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.001	0.998	0.000
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.001	0.998	0.000
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.001	0.998	0.000
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.001	0.998	0.000
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.001	0.998	0.000
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.001	0.998	0.000
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.998	0.000
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.001	0.998	0.000
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.001	0.998	0.000
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.001	0.998	0.000
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.001	0.998	0.000
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.001	0.998	0.000
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.001	0.998	0.000
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.001	0.998	0.000
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.001	0.998	0.000
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.001	0.998	0.000
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.998	0.000
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)	0.001	0.998	0.000
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)	0.001	0.998	0.000
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)	0.001	0.998	0.000
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)	0.001	0.998	0.000
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)	0.001	0.998	0.000
M80.89 Other osteoporosis with pathological fracture (Site unspecified)	0.001	0.998	0.000
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)	0.001	0.998	0.000
M80.86 Other osteoporosis with pathological fracture (Lower leg)	0.001	0.998	0.000
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.998	0.000
M80.84 Other osteoporosis with pathological fracture (Hand)	0.001	0.998	0.000
M80.83 Other osteoporosis with pathological fracture (Forearm)	0.001	0.998	0.000
M80.82 Other osteoporosis with pathological fracture (Upper arm)	0.001	0.998	0.000
M80.81 Other osteoporosis with pathological fracture (Shoulder region)	0.001	0.998	0.000
M80.80 Other osteoporosis with pathological fracture (Multiple sites)	0.001	0.998	0.000
M82.09 Osteoporosis in multiple myelomatosis (Site unspecified)	0.001	0.998	0.000
M82.08 Osteoporosis in multiple myelomatosis (Other)	0.001	0.998	0.000
M82.07 Osteoporosis in multiple myelomatosis (Ankle and foot)	0.001	0.998	0.000
M82.06 Osteoporosis in multiple myelomatosis (Lower leg)	0.001	0.998	0.000
M82.05 Osteoporosis in multiple myelomatosis (Pelvic region and thigh)	0.001	0.998	0.000
M82.04 Osteoporosis in multiple myelomatosis (Hand)	0.001	0.998	0.000
M82.03 Osteoporosis in multiple myelomatosis (Forearm)	0.001	0.998	0.000
M82.02 Osteoporosis in multiple myelomatosis (Upper arm)	0.001	0.998	0.000
M82.01 Osteoporosis in multiple myelomatosis (Shoulder region)	0.001	0.998	0.000
M82.00 Osteoporosis in multiple myelomatosis (Multiple sites)	0.001	0.998	0.000
M82.89 Osteoporosis in other diseases classified elsewhere (Site unspecified)	0.001	0.998	0.000
M82.88 Osteoporosis in other diseases classified elsewhere (Other)	0.001	0.998	0.000
M82.87 Osteoporosis in other diseases classified elsewhere (Ankle and foot)	0.001	0.998	0.000
M82.86 Osteoporosis in other diseases classified elsewhere (Lower leg)	0.001	0.998	0.000
M82.85 Osteoporosis in other diseases classified elsewhere (Pelvic region and thigh)	0.001	0.998	0.000
M82.84 Osteoporosis in other diseases classified elsewhere (Hand)	0.001	0.998	0.000
M82.83 Osteoporosis in other diseases classified elsewhere (Forearm)	0.001	0.998	0.000
M82.82 Osteoporosis in other diseases classified elsewhere (Upper arm)	0.001	0.998	0.000
M82.81 Osteoporosis in other diseases classified elsewhere (Shoulder region)	0.001	0.998	0.000
M82.80 Osteoporosis in other diseases classified elsewhere (Multiple sites)	0.001	0.998	0.000
M85.97 Disorder of bone density and structure, unspecified (Ankle and foot)	0.001	0.998	0.000
M85.96 Disorder of bone density and structure, unspecified (Lower leg)	0.001	0.998	0.000
M85.94 Disorder of bone density and structure, unspecified (Hand)	0.001	0.998	0.000
M85.93 Disorder of bone density and structure, unspecified (Forearm)	0.001	0.998	0.000
M85.92 Disorder of bone density and structure, unspecified (Upper arm)	0.001	0.998	0.000
M85.91 Disorder of bone density and structure, unspecified (Shoulder region)	0.001	0.998	0.000
M85.90 Disorder of bone density and structure, unspecified (Multiple sites)	0.001	0.998	0.000
M89.98 Disorder of bone, unspecified (Other)	0.001	0.998	0.000
S92.41 Fracture of great toe (open)	0.001	0.998	0.000
A04.5 Campylobacter enteritis	0.000	0.998	0.002
M83.1 Senile osteomalacia	0.001	0.998	0.000
S98.1 Traumatic amputation of one toe	0.001	0.998	0.000
Z61.5 Problems related to alleged sexual abuse of child by person outside primary support group	0.001	0.998	0.000
Z76.8 Persons encountering health services in other specified circumstances	0.000	0.998	0.002
S42 Fracture of shoulder and upper arm	0.002	0.998	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.998	0.001
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.000	0.998	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations