TreeWAS – Variant ID: rs6915934

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	0.000	0.000	1.000
E83.1 Disorders of iron metabolism	0.000	0.000	1.000
E10 Insulin-dependent diabetes mellitus	0.000	0.528	0.472
E10.9 Without complications	0.000	0.531	0.469
E10.4 With neurological complications	0.000	0.559	0.441
E10.5 With peripheral circulatory complications	0.000	0.566	0.434
E10.6 With other specified complications	0.000	0.574	0.426
E10.8 With unspecified complications	0.000	0.602	0.398
E10.1 With ketoacidosis	0.000	0.645	0.355
E10.2 With renal complications	0.000	0.647	0.353
E10-E14 Diabetes mellitus	0.000	0.649	0.351
E10.7 With multiple complications	0.000	0.661	0.339
E10.0 With coma	0.000	0.680	0.320
E10.3 With ophthalmic complications	0.000	0.689	0.311
K90 Intestinal malabsorption	0.000	0.692	0.308
E83 Disorders of mineral metabolism	0.000	0.695	0.305
E13 Other specified diabetes mellitus	0.000	0.702	0.298
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.737	0.263
E13.9 Without complications	0.000	0.738	0.261
E14 Unspecified diabetes mellitus	0.000	0.739	0.261
E70-E90 Metabolic disorders	0.000	0.740	0.260
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.746	0.254
E12 Malnutrition-related diabetes mellitus	0.000	0.748	0.252
E14.3 With ophthalmic complications	0.000	0.751	0.249
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.775	0.225
K90.3 Pancreatic steatorrhoea	0.000	0.779	0.221
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.779	0.221
K90.1 Tropical sprue	0.000	0.779	0.221
E40-E46 Malnutrition	0.000	0.780	0.220
E88 Other metabolic disorders	0.000	0.780	0.220
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.781	0.219
E83.8 Other disorders of mineral metabolism	0.000	0.781	0.219
E83.2 Disorders of zinc metabolism	0.000	0.781	0.219
E83.0 Disorders of copper metabolism	0.000	0.781	0.219
E13.8 With unspecified complications	0.000	0.786	0.213
E13.7 With multiple complications	0.000	0.786	0.213
E13.6 With other specified complications	0.000	0.786	0.213
E13.5 With peripheral circulatory complications	0.000	0.786	0.213
E13.4 With neurological complications	0.000	0.786	0.213
E13.2 With renal complications	0.000	0.786	0.213
E13.1 With ketoacidosis	0.000	0.786	0.213
E13.0 With coma	0.000	0.786	0.213
K90.8 Other intestinal malabsorption	0.000	0.787	0.213
E85 Amyloidosis	0.000	0.789	0.211
E13.3 With ophthalmic complications	0.000	0.791	0.209
E16 Other disorders of pancreatic internal secretion	0.000	0.802	0.198
E14.5 With peripheral circulatory complications	0.000	0.805	0.195
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.807	0.193
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.810	0.190
E46 Unspecified protein-energy malnutrition	0.000	0.810	0.190
E14.7 With multiple complications	0.000	0.813	0.187
E14.6 With other specified complications	0.000	0.813	0.187
E14.2 Withrenal complications	0.000	0.813	0.187
E14.0 With coma	0.000	0.813	0.187
E84 Cystic fibrosis	0.000	0.813	0.186
E77 Disorders of glycoprotein metabolism	0.000	0.813	0.186
E76 Disorders of glycosaminoglycan metabolism	0.000	0.813	0.186
E72 Other disorders of amino-acid metabolism	0.000	0.813	0.186
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.813	0.186
E70 Disorders of aromatic amino-acid metabolism	0.000	0.813	0.186
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.813	0.186
E16.2 Hypoglycaemia, unspecified	0.000	0.814	0.186
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.817	0.183
E12.9 Without complications	0.000	0.819	0.181
E12.8 With unspecified complications	0.000	0.819	0.181
E12.7 With multiple complications	0.000	0.819	0.181
E12.6 With other specified complications	0.000	0.819	0.181
E12.5 With peripheral circulatory complications	0.000	0.819	0.181
E12.4 With neurological complications	0.000	0.819	0.181
E12.3 With ophthalmic complications	0.000	0.819	0.181
E12.2 With renal complications	0.000	0.819	0.181
E12.1 With ketoacidosis	0.000	0.819	0.181
E12.0 With coma	0.000	0.819	0.181
E14.4 With neurological complications	0.000	0.819	0.181
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.821	0.179
E65-E68 Obesity and other hyperalimentation	0.000	0.822	0.178
E85.9 Amyloidosis, unspecified	0.000	0.824	0.176
E79 Disorders of purine and pyrimidine metabolism	0.000	0.831	0.169
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.832	0.167
E88.8 Other specified metabolic disorders	0.000	0.833	0.167
E88.2 Lipomatosis, not elsewhere classified	0.000	0.834	0.166
E15 Nondiabetic hypoglycaemic coma	0.000	0.838	0.162
E85.4 Organ-limited amyloidosis	0.000	0.841	0.159
E88.3 Tumour lysis syndrome	0.000	0.842	0.158
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.842	0.158
E45 Retarded development following protein-energy malnutrition	0.000	0.842	0.158
E43 Unspecified severe protein-energy malnutrition	0.000	0.842	0.158
E42 Marasmic kwashiorkor	0.000	0.842	0.158
E41 Nutritional marasmus	0.000	0.842	0.158
E40 Kwashiorkor	0.000	0.842	0.158
E14.1 With ketoacidosis	0.000	0.845	0.155
E89.2 Postprocedural hypoparathyroidism	0.000	0.845	0.155
E14.8 With unspecified complications	0.000	0.845	0.155
E11 Non-insulin-dependent diabetes mellitus	0.000	0.846	0.154
E65 Localised adiposity	0.000	0.848	0.152
E85.8 Other amyloidosis	0.000	0.849	0.151
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.849	0.151
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.849	0.151
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.849	0.151
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.851	0.149
E74 Other disorders of carbohydrate metabolism	0.000	0.852	0.147
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.853	0.147
E88.9 Metabolic disorder, unspecified	0.000	0.853	0.147
E89.4 Postprocedural ovarian failure	0.000	0.856	0.144
E89.0 Postprocedural hypothyroidism	0.000	0.856	0.144
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.857	0.142
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.857	0.142
E16.4 Abnormal secretion of gastrin	0.000	0.857	0.142
E16.3 Increased secretion of glucagon	0.000	0.857	0.142
E85.3 Secondary systemic amyloidosis	0.000	0.859	0.141
E75.5 Other lipid storage disorders	0.000	0.859	0.141
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.862	0.138
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.862	0.138
E89.5 Postprocedural testicular hypofunction	0.000	0.862	0.138
E89.1 Postprocedural hypoinsulinaemia	0.000	0.862	0.138
E80.4 Gilbert's syndrome	0.000	0.862	0.138
E73 Lactose intolerance	0.000	0.863	0.137
E75.6 Lipid storage disorder, unspecified	0.000	0.863	0.137
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.863	0.137
E75.3 Sphingolipidosis, unspecified	0.000	0.863	0.137
E75.2 Other sphingolipidosis	0.000	0.863	0.137
E75.1 Other gangliosidosis	0.000	0.863	0.137
E75.0 GM2 gangliosidosis	0.000	0.863	0.137
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.866	0.134
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.866	0.134
E70.3 Albinism	0.000	0.866	0.134
E70.2 Disorders of tyrosine metabolism	0.000	0.866	0.134
E70.1 Other hyperphenylalaninaemias	0.000	0.866	0.134
E70.0 Classical phenylketonuria	0.000	0.866	0.134
E71.3 Disorders of fatty-acid metabolism	0.000	0.866	0.134
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.866	0.134
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.866	0.134
E71.0 Maple-syrup-urine disease	0.000	0.866	0.134
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.866	0.134
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.866	0.134
E72.5 Disorders of glycine metabolism	0.000	0.866	0.134
E72.4 Disorders of ornithine metabolism	0.000	0.866	0.134
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.866	0.134
E72.2 Disorders of urea cycle metabolism	0.000	0.866	0.134
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.866	0.134
E72.0 Disorders of amino-acid transport	0.000	0.866	0.134
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.866	0.134
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.866	0.134
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.866	0.134
E76.2 Other mucopolysaccharidoses	0.000	0.866	0.134
E76.1 Mucopolysaccharidosis, type II	0.000	0.866	0.134
E76.0 Mucopolysaccharidosis, type I	0.000	0.866	0.134
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.866	0.134
E77.8 Other disorders of glycoprotein metabolism	0.000	0.866	0.134
E77.1 Defects in glycoprotein degradation	0.000	0.866	0.134
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.866	0.134
E84.9 Cystic fibrosis, unspecified	0.000	0.866	0.134
E84.8 Cystic fibrosis with other manifestations	0.000	0.866	0.134
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.866	0.134
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.866	0.134
E83.3 Disorders of phosphorus metabolism	0.000	0.868	0.132
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.868	0.131
E80.5 Crigler-Najjar syndrome	0.000	0.868	0.131
E80.3 Defects of catalase and peroxydase	0.000	0.868	0.131
E80.1 Porphyria cutanea tarda	0.000	0.868	0.131
E80.0 Hereditary erythropoietic porphyria	0.000	0.868	0.131
E67 Other hyperalimentation	0.000	0.872	0.127
E68 Sequelae of hyperalimentation	0.000	0.872	0.127
E83.4 Disorders of magnesium metabolism	0.000	0.873	0.127
E80.2 Other porphyria	0.000	0.874	0.126
E11.5 With peripheral circulatory complications	0.000	0.874	0.126
E80.6 Other disorders of bilirubin metabolism	0.000	0.875	0.125
E00-E07 Disorders of thyroid gland	0.000	0.878	0.122
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.878	0.122
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.879	0.121
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.879	0.121
E79.1 Lesch-Nyhan syndrome	0.000	0.879	0.121
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.882	0.118
E11.0 With coma	0.000	0.882	0.118
E11.8 With unspecified complications	0.000	0.885	0.115
E44.1 Mild protein-energy malnutrition	0.000	0.886	0.113
E44.0 Moderate protein-energy malnutrition	0.000	0.886	0.113
E11.2 With renal complications	0.000	0.888	0.112
E11.1 With ketoacidosis	0.000	0.889	0.111
E11.7 With multiple complications	0.000	0.890	0.110
E16.1 Other hypoglycaemia	0.000	0.892	0.108
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.894	0.106
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.894	0.106
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.894	0.106
E74.2 Disorders of galactose metabolism	0.000	0.894	0.106
E74.1 Disorders of fructose metabolism	0.000	0.894	0.106
E11.6 With other specified complications	0.000	0.894	0.106
E11.4 With neurological complications	0.000	0.896	0.104
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.896	0.104
E78.4 Other hyperlipidaemia	0.000	0.901	0.099
E73.8 Other lactose intolerance	0.000	0.901	0.098
E73.1 Secondary lactase deficiency	0.000	0.901	0.098
E73.0 Congenital lactase deficiency	0.000	0.901	0.098
E74.0 Glycogen storage disease	0.000	0.903	0.097
E07 Other disorders of thyroid	0.000	0.904	0.096
E04 Other non-toxic goitre	0.000	0.907	0.093
E78.6 Lipoprotein deficiency	0.000	0.908	0.092
E67.8 Other specified hyperalimentation	0.000	0.908	0.092
E67.3 Hypervitaminosis D	0.000	0.908	0.092
E67.2 Megavitamin-B6 syndrome	0.000	0.908	0.092
E67.1 Hypercarotenaemia	0.000	0.908	0.092
E67.0 Hypervitaminosis A	0.000	0.908	0.092
K90.9 Intestinal malabsorption, unspecified	0.001	0.910	0.089
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.912	0.088
E00 Congenital iodine-deficiency syndrome	0.000	0.912	0.088
E78.3 Hyperchylomicronaemia	0.000	0.912	0.088
E50-E64 Other nutritional deficiencies	0.000	0.914	0.085
E87 Other disorders of fluid, electrolyte and acid-base balance	0.000	0.915	0.085
E89.3 Postprocedural hypopituitarism	0.000	0.916	0.084
E06 Thyroiditis	0.000	0.917	0.083
E78.1 Pure hyperglyceridaemia	0.000	0.917	0.083
E04.9 Non-toxic goitre, unspecified	0.000	0.918	0.082
E07.9 Disorder of thyroid, unspecified	0.000	0.919	0.081
E20-E35 Disorders of other endocrine glands	0.000	0.919	0.081
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.919	0.080
E11.3 With ophthalmic complications	0.000	0.919	0.081
E78.2 Mixed hyperlipidaemia	0.000	0.920	0.080
E03 Other hypothyroidism	0.000	0.920	0.080
E87.3 Alkalosis	0.000	0.922	0.078
E83.5 Disorders of calcium metabolism	0.000	0.923	0.077
E03.8 Other specified hypothyroidism	0.000	0.928	0.072
E87.0 Hyperosmolality and hypernatraemia	0.000	0.929	0.071
E04.0 Non-toxic diffuse goitre	0.000	0.929	0.070
E07.1 Dyshormogenetic goitre	0.000	0.931	0.069
E07.0 Hypersecretion of calcitonin	0.000	0.931	0.069
E14.9 Without complications	0.000	0.932	0.068
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.933	0.067
E04.8 Other specified non-toxic goitre	0.000	0.933	0.067
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.937	0.063
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.937	0.063
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.937	0.063
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.937	0.063
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.937	0.063
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.937	0.063
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.937	0.063
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.937	0.063
E28 Ovarian dysfunction	0.000	0.937	0.063
E06.3 Autoimmune thyroiditis	0.000	0.938	0.062
E87.7 Fluid overload	0.000	0.938	0.062
E20 Hypoparathyroidism	0.000	0.938	0.062
E04.2 Non-toxic multinodular goitre	0.000	0.938	0.062
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.938	0.061
E63 Other nutritional deficiencies	0.000	0.938	0.061
E56 Other vitamin deficiencies	0.000	0.938	0.061
E50 Vitamin A deficiency	0.000	0.938	0.061
E60 Dietary zinc deficiency	0.000	0.938	0.061
E59 Dietary selenium deficiency	0.000	0.938	0.061
E54 Ascorbic acid deficiency	0.000	0.938	0.061
E52 Niacin deficiency [pellagra]	0.000	0.938	0.061
E87.4 Mixed disorder of acid-base balance	0.000	0.939	0.061
E07.8 Other specified disorders of thyroid	0.000	0.939	0.061
E26 Hyperaldosteronism	0.000	0.939	0.061
E58 Dietary calcium deficiency	0.000	0.939	0.061
E87.2 Acidosis	0.000	0.939	0.061
E06.5 Other chronic thyroiditis	0.000	0.940	0.060
E06.4 Drug-induced thyroiditis	0.000	0.940	0.060
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.940	0.060
E06.1 Subacute thyroiditis	0.000	0.940	0.060
E06.0 Acute thyroiditis	0.000	0.940	0.060
E66 Obesity	0.000	0.940	0.060
E29 Testicular dysfunction	0.000	0.941	0.059
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.941	0.058
E32 Diseases of thymus	0.000	0.941	0.058
E31 Polyglandular dysfunction	0.000	0.941	0.058
E30 Disorders of puberty, not elsewhere classified	0.000	0.941	0.058
E25 Adrenogenital disorders	0.000	0.941	0.058
E23 Hypofunction and other disorders of pituitary gland	0.000	0.942	0.058
E03.5 Myxoedema coma	0.000	0.942	0.058
E03.4 Atrophy of thyroid (acquired)	0.000	0.942	0.058
E03.3 Postinfectious hypothyroidism	0.000	0.942	0.058
E03.1 Congenital hypothyroidism without goitre	0.000	0.942	0.058
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.942	0.058
E51 Thiamine deficiency	0.000	0.943	0.057
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.943	0.056
E28.2 Polycystic ovarian syndrome	0.000	0.944	0.056
E53 Deficiency of other B group vitamins	0.000	0.945	0.055
E34 Other endocrine disorders	0.000	0.947	0.053
E23.2 Diabetes insipidus	0.000	0.947	0.053
E06.9 Thyroiditis, unspecified	0.000	0.947	0.053
E24 Cushing's syndrome	0.000	0.947	0.053
E78.8 Other disorders of lipoprotein metabolism	0.000	0.948	0.052
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.948	0.052
E27 Other disorders of adrenal gland	0.000	0.949	0.051
E87.5 Hyperkalaemia	0.000	0.950	0.050
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.950	0.050
E73.9 Lactose intolerance, unspecified	0.001	0.951	0.048
E55 Vitamin D deficiency	0.000	0.951	0.049
E20.9 Hypoparathyroidism, unspecified	0.000	0.952	0.048
E27.1 Primary adrenocortical insufficiency	0.000	0.952	0.048
E04.1 Non-toxic single thyroid nodule	0.000	0.953	0.047
E26.0 Primary hyperaldosteronism	0.000	0.953	0.047
E28.9 Ovarian dysfunction, unspecified	0.000	0.955	0.045
E28.8 Other ovarian dysfunction	0.000	0.955	0.045
E28.1 Androgen excess	0.000	0.955	0.045
E28.0 Oestrogen excess	0.000	0.955	0.045
E20.8 Other hypoparathyroidism	0.000	0.955	0.044
E20.1 Pseudohypoparathyroidism	0.000	0.955	0.044
E20.0 Idiopathic hypoparathyroidism	0.000	0.955	0.044
E50.9 Vitamin A deficiency, unspecified	0.000	0.956	0.044
E50.8 Other manifestations of vitamin A deficiency	0.000	0.956	0.044
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.956	0.044
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.956	0.044
E50.5 Vitamin A deficiency with night blindness	0.000	0.956	0.044
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.956	0.044
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.956	0.044
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.956	0.044
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.956	0.044
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.956	0.044
E56.9 Vitamin deficiency, unspecified	0.000	0.956	0.044
E56.8 Deficiency of other vitamins	0.000	0.956	0.044
E56.1 Deficiency of vitamin K	0.000	0.956	0.044
E56.0 Deficiency of vitamin E	0.000	0.956	0.044
E63.9 Nutritional deficiency, unspecified	0.000	0.956	0.044
E63.8 Other specified nutritional deficiencies	0.000	0.956	0.044
E63.1 Imbalance of constituents of food intake	0.000	0.956	0.044
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.956	0.044
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.956	0.044
E64.8 Sequelae of other nutritional deficiencies	0.000	0.956	0.044
E64.3 Sequelae of rickets	0.000	0.956	0.044
E64.2 Sequelae of vitamin C deficiency	0.000	0.956	0.044
E64.1 Sequelae of vitamin A deficiency	0.000	0.956	0.044
E64.0 Sequelae of protein-energy malnutrition	0.000	0.956	0.044
E26.9 Hyperaldosteronism, unspecified	0.000	0.956	0.044
E26.8 Other hyperaldosteronism	0.000	0.956	0.044
E26.1 Secondary hyperaldosteronism	0.000	0.956	0.044
E24.2 Drug-induced Cushing's syndrome	0.000	0.956	0.044
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.000	0.956	0.043
E66.1 Drug-induced obesity	0.000	0.957	0.043
E29.1 Testicular hypofunction	0.000	0.957	0.043
E29.9 Testicular dysfunction, unspecified	0.000	0.958	0.042
E29.8 Other testicular dysfunction	0.000	0.958	0.042
E29.0 Testicular hyperfunction	0.000	0.958	0.042
E25.9 Adrenogenital disorder, unspecified	0.000	0.958	0.042
E25.8 Other adrenogenital disorders	0.000	0.958	0.042
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.958	0.042
E30.9 Disorder of puberty, unspecified	0.000	0.958	0.042
E30.8 Other disorders of puberty	0.000	0.958	0.042
E30.1 Precocious puberty	0.000	0.958	0.042
E30.0 Delayed puberty	0.000	0.958	0.042
E31.9 Polyglandular dysfunction, unspecified	0.000	0.958	0.042
E31.8 Other polyglandular dysfunction	0.000	0.958	0.042
E31.1 Polyglandular hyperfunction	0.000	0.958	0.042
E31.0 Autoimmune polyglandular failure	0.000	0.958	0.042
E32.9 Disease of thymus, unspecified	0.000	0.958	0.042
E32.8 Other diseases of thymus	0.000	0.958	0.042
E32.1 Abscess of thymus	0.000	0.958	0.042
E32.0 Persistent hyperplasia of thymus	0.000	0.958	0.042
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.958	0.042
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.958	0.042
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.958	0.042
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.958	0.042
E23.1 Drug-induced hypopituitarism	0.000	0.958	0.042
E66.0 Obesity due to excess calories	0.000	0.958	0.041
E51.9 Thiamine deficiency, unspecified	0.000	0.959	0.041
E51.8 Other manifestations of thiamine deficiency	0.000	0.959	0.041
E51.1 Beriberi	0.000	0.959	0.041
E23.7 Disorder of pituitary gland, unspecified	0.000	0.959	0.041
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.959	0.041
E53.1 Pyridoxine deficiency	0.000	0.960	0.039
E53.0 Riboflavin deficiency	0.000	0.960	0.039
E53.9 Vitamin B deficiency, unspecified	0.000	0.961	0.039
E05.8 Other thyrotoxicosis	0.000	0.961	0.039
E34.5 Androgen resistance syndrome	0.000	0.961	0.038
E34.4 Constitutional tall stature	0.000	0.961	0.038
E34.3 Short stature, not elsewhere classified	0.000	0.961	0.038
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.961	0.038
E34.1 Other hypersecretion of intestinal hormones	0.000	0.961	0.038
E34.9 Endocrine disorder, unspecified	0.000	0.962	0.038
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.962	0.038
E24.8 Other Cushing's syndrome	0.000	0.962	0.038
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.962	0.038
E24.3 Ectopic ACTH syndrome	0.000	0.962	0.038
E24.1 Nelson's syndrome	0.000	0.962	0.038
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.962	0.038
E05.5 Thyroid crisis or storm	0.000	0.962	0.037
E05.4 Thyrotoxicosis factitia	0.000	0.962	0.037
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.962	0.037
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.962	0.037
E34.8 Other specified endocrine disorders	0.000	0.963	0.037
E27.5 Adrenomedullary hyperfunction	0.000	0.963	0.037
E27.0 Other adrenocortical overactivity	0.000	0.963	0.037
E23.6 Other disorders of pituitary gland	0.000	0.963	0.037
E51.2 Wernicke's encephalopathy	0.000	0.964	0.036
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.964	0.036
E55.0 Rickets, active	0.000	0.965	0.035
E34.0 Carcinoid syndrome	0.000	0.965	0.035
E24.0 Pituitary-dependent Cushing's disease	0.000	0.966	0.034
E53.8 Deficiency of other specified B group vitamins	0.000	0.967	0.033
E61 Deficiency of other nutrient elements	0.001	0.967	0.032
E28.3 Primary ovarian failure	0.000	0.971	0.028
E27.2 Addisonian crisis	0.000	0.971	0.028
E21.3 Hyperparathyroidism, unspecified	0.000	0.972	0.028
E21.4 Other specified disorders of parathyroid gland	0.000	0.973	0.027
E21.2 Other hyperparathyroidism	0.000	0.973	0.027
E86 Volume depletion	0.000	0.973	0.027
E24.9 Cushing's syndrome, unspecified	0.000	0.974	0.026
E22 Hyperfunction of pituitary gland	0.000	0.974	0.026
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.974	0.025
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.975	0.025
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.975	0.025
E27.8 Other specified disorders of adrenal gland	0.000	0.976	0.024
E61.9 Deficiency of nutrient element, unspecified	0.001	0.976	0.023
E61.8 Deficiency of other specified nutrient elements	0.001	0.976	0.023
E61.7 Deficiency of multiple nutrient elements	0.001	0.976	0.023
E61.6 Vanadium deficiency	0.001	0.976	0.023
E61.5 Molybdenum deficiency	0.001	0.976	0.023
E61.4 Chromium deficiency	0.001	0.976	0.023
E61.3 Manganese deficiency	0.001	0.976	0.023
E61.0 Copper deficiency	0.001	0.976	0.023
E55.9 Vitamin D deficiency, unspecified	0.000	0.977	0.022
E27.9 Disorder of adrenal gland, unspecified	0.000	0.978	0.021
E23.0 Hypopituitarism	0.000	0.979	0.021
K90-K93 Other diseases of the digestive system	0.000	0.980	0.020
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.981	0.019
E22.8 Other hyperfunction of pituitary gland	0.000	0.981	0.019
E61.2 Magnesium deficiency	0.001	0.981	0.018
E66.9 Obesity, unspecified	0.000	0.983	0.017
E22.1 Hyperprolactinaemia	0.000	0.983	0.017
R31 Unspecified haematuria	0.015	0.985	0.000
E21.0 Primary hyperparathyroidism	0.000	0.985	0.015
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.986	0.014
C71.2 Temporal lobe	0.014	0.986	0.000
C71 Malignant neoplasm of brain	0.013	0.987	0.000
C71.9 Brain, unspecified	0.013	0.987	0.000
E22.0 Acromegaly and pituitary gigantism	0.000	0.988	0.012
E05.9 Thyrotoxicosis, unspecified	0.000	0.988	0.012
C71.3 Parietal lobe	0.011	0.989	0.000
E87.6 Hypokalaemia	0.000	0.989	0.011
M41.9 Scoliosis, unspecified	0.011	0.989	0.000
C71.1 Frontal lobe	0.011	0.989	0.000
M41.96 Scoliosis, unspecified (Lumbar region)	0.011	0.989	0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.989	0.010
K93.1 Megacolon in Chagas' disease	0.000	0.989	0.010
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.989	0.010
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.010	0.990	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.010	0.990	0.000
M41.94 Scoliosis, unspecified (Thoracic region)	0.010	0.990	0.000
C71.7 Brain stem	0.010	0.990	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.001	0.990	0.009
C71.6 Cerebellum	0.010	0.990	0.000
C71.5 Cerebral ventricle	0.010	0.990	0.000
C71.0 Cerebrum, except lobes and ventricles	0.010	0.990	0.000
C71.8 Overlapping lesion of brain	0.009	0.990	0.000
G31.8 Other specified degenerative diseases of nervous system	0.000	0.991	0.009
G44.2 Tension-type headache	0.009	0.991	0.000
E61.1 Iron deficiency	0.001	0.992	0.007
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.992	0.008
C71.4 Occipital lobe	0.008	0.992	0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.008	0.992	0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.008	0.992	0.000
M41.92 Scoliosis, unspecified (Cervical region)	0.008	0.992	0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.008	0.992	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.008	0.992	0.000
G31.0 Circumscribed brain atrophy	0.000	0.992	0.008
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.008	0.992	0.000
E66.8 Other obesity	0.000	0.993	0.007
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.993	0.007
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.007	0.993	0.000
C69 Malignant neoplasm of eye and adnexa	0.007	0.993	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.007	0.993	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.000	0.994	0.006
C70 Malignant neoplasm of meninges	0.006	0.994	0.000
N04.9 Unspecified	0.000	0.994	0.006
C69.9 Eye, unspecified	0.006	0.994	0.000
M79.10 Myalgia (Multiple sites)	0.006	0.994	0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.005	0.994	0.000
C69.3 Choroid	0.005	0.995	0.000
M41 Scoliosis	0.005	0.995	0.000
G31.2 Degeneration of nervous system due to alcohol	0.000	0.995	0.005
C69.8 Overlapping lesion of eye and adnexa	0.005	0.995	0.000
C69.5 Lachrymal gland and duct	0.005	0.995	0.000
C69.4 Ciliary body	0.005	0.995	0.000
C69.2 Retina	0.005	0.995	0.000
C69.1 Cornea	0.005	0.995	0.000
C70.0 Cerebral meninges	0.005	0.995	0.000
G30-G32 Other degenerative diseases of the nervous system	0.000	0.995	0.005
C69.6 Orbit	0.005	0.995	0.000
C69.0 Conjunctiva	0.005	0.995	0.000
G30 Alzheimer's disease	0.000	0.995	0.005
G54.9 Nerve root and plexus disorder, unspecified	0.005	0.995	0.000
C70.9 Meninges, unspecified	0.004	0.995	0.000
C70.1 Spinal meninges	0.004	0.995	0.000
G44 Other headache syndromes	0.005	0.995	0.000
M67.8 Other specified disorders of synovium and tendon	0.000	0.995	0.005
Z86.1 Personal history of infectious and parasitic diseases	0.000	0.996	0.004
G30.0 Alzheimer's disease with early onset	0.000	0.996	0.004
R52.1 Chronic intractable pain	0.004	0.996	0.000
C72.9 Central nervous system, unspecified	0.004	0.996	0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.004	0.996	0.000
C72.5 Other and unspecified cranial nerves	0.004	0.996	0.000
C72.4 Acoustic nerve	0.004	0.996	0.000
C72.3 Optic nerve	0.004	0.996	0.000
C72.2 Olfactory nerve	0.004	0.996	0.000
C72.1 Cauda equina	0.004	0.996	0.000
I31.9 Disease of pericardium, unspecified	0.000	0.996	0.004
G44.8 Other specified headache syndromes	0.004	0.996	0.000
G30.9 Alzheimer's disease, unspecified	0.000	0.996	0.004
M41.5 Other secondary scoliosis	0.004	0.996	0.000
M41.4 Neuromuscular scoliosis	0.004	0.996	0.000
M41.3 Thoracogenic scoliosis	0.004	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations