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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs6916278
log Bayes Factor = 25.9034
Chromosome 6   position 31,678,774  (GRCh37) Explore rs6916278 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
L40-L45 Papulosquamous disorders
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.001 0.999
L40.5 Arthropathic psoriasis
0.000 0.001 0.999
M05-M14 Inflammatory polyarthropathies
0.000 0.003 0.997
E10.3 With ophthalmic complications
0.000 0.008 0.992
# Top node
0.000 0.009 0.991
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.014 0.986
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.015 0.985
K90.0 Coeliac disease
0.985 0.015 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.025 0.975
Chapter X Diseases of the respiratory system
0.000 0.026 0.974
M07 Psoriatic and enteropathic arthropathies
0.000 0.027 0.973
L20-L30 Dermatitis and eczema
0.000 0.030 0.970
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.035 0.965
M06.0 Seronegative rheumatoid arthritis
0.000 0.039 0.961
L57.0 Actinic keratosis
0.000 0.041 0.959
D60-D64 Aplastic and other anaemias
0.000 0.044 0.956
M07.3 Other psoriatic arthropathies
0.000 0.045 0.955
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.046 0.954
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.052 0.948
L00-L08 Infections of the skin and subcutaneous tissue
0.000 0.053 0.947
L29 Pruritus
0.000 0.054 0.946
E10.1 With ketoacidosis
0.000 0.066 0.934
Chapter I Certain infectious and parasitic diseases
0.000 0.069 0.931
E06 Thyroiditis
0.000 0.074 0.926
M05 Seropositive rheumatoid arthritis
0.000 0.078 0.922
L29.0 Pruritus ani
0.000 0.079 0.921
L08 Other local infections of skin and subcutaneous tissue
0.000 0.082 0.918
J09-J18 Influenza and pneumonia
0.000 0.082 0.918
B35-B49 Mycoses
0.000 0.092 0.908
J81 Pulmonary oedema
0.000 0.092 0.908
D64 Other anaemias
0.000 0.094 0.906
E05.9 Thyrotoxicosis, unspecified
0.000 0.094 0.906
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.100 0.900
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.000 0.101 0.899
D50-D53 Nutritional anaemias
0.000 0.101 0.899
B37 Candidiasis
0.000 0.104 0.896
D61 Other aplastic anaemias
0.000 0.106 0.894
B37.8 Candidiasis of other sites
0.000 0.107 0.893
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.108 0.892
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.108 0.892
E10.5 With peripheral circulatory complications
0.000 0.111 0.889
J18 Pneumonia, organism unspecified
0.000 0.115 0.885
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.119 0.881
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.122 0.878
E10.4 With neurological complications
0.000 0.125 0.875
D64.9 Anaemia, unspecified
0.000 0.129 0.871
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.130 0.870
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.131 0.869
E50-E64 Other nutritional deficiencies
0.000 0.133 0.867
J18.1 Lobar pneumonia, unspecified
0.000 0.136 0.864
E06.3 Autoimmune thyroiditis
0.000 0.138 0.862
J40-J47 Chronic lower respiratory diseases
0.000 0.141 0.859
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.148 0.852
D61.9 Aplastic anaemia, unspecified
0.000 0.150 0.850
J80 Adult respiratory distress syndrome
0.000 0.150 0.850
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.152 0.848
E65-E68 Obesity and other hyperalimentation
0.000 0.158 0.842
D50 Iron deficiency anaemia
0.000 0.159 0.841
B25-B34 Other viral diseases
0.000 0.160 0.840
L40.0 Psoriasis vulgaris
0.000 0.168 0.832
E70-E90 Metabolic disorders
0.000 0.169 0.831
M35.3 Polymyalgia rheumatica
0.000 0.172 0.828
M35 Other systemic involvement of connective tissue
0.000 0.172 0.828
D68 Other coagulation defects
0.000 0.172 0.828
M20-M25 Other joint disorders
0.000 0.173 0.827
D80-D89 Certain disorders involving the immune mechanism
0.000 0.173 0.827
J47 Bronchiectasis
0.000 0.177 0.823
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.182 0.818
E20-E35 Disorders of other endocrine glands
0.000 0.195 0.805
D50.9 Iron deficiency anaemia, unspecified
0.000 0.210 0.790
E27 Other disorders of adrenal gland
0.000 0.212 0.788
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.214 0.785
E86 Volume depletion
0.000 0.217 0.783
M14 Arthropathies in other diseases classified elsewhere
0.000 0.219 0.781
A50-A64 Infections with a predominantly sexual mode of transmission
0.000 0.223 0.777
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.226 0.774
L02 Cutaneous abscess, furuncle and carbuncle
0.000 0.226 0.774
J20-J22 Other acute lower respiratory infections
0.000 0.227 0.773
L27 Dermatitis due to substances taken internally
0.000 0.233 0.767
J10 Influenza due to identified influenza virus
0.000 0.234 0.766
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.235 0.765
L29.9 Pruritus, unspecified
0.000 0.239 0.761
J30-J39 Other diseases of upper respiratory tract
0.000 0.241 0.759
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.245 0.755
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.245 0.755
E53 Deficiency of other B group vitamins
0.000 0.249 0.751
L43 Lichen planus
0.000 0.250 0.750
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.252 0.748
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.255 0.745
E04 Other non-toxic goitre
0.000 0.257 0.743
B37.0 Candidal stomatitis
0.000 0.260 0.740
D86 Sarcoidosis
0.000 0.260 0.740
E66 Obesity
0.000 0.261 0.739
D55-D59 Haemolytic anaemias
0.000 0.267 0.733
L28 Lichen simplex chronicus and prurigo
0.000 0.269 0.731
J18.9 Pneumonia, unspecified
0.000 0.269 0.731
D68.9 Coagulation defect, unspecified
0.000 0.272 0.728
E27.1 Primary adrenocortical insufficiency
0.000 0.273 0.727
B34 Viral infection of unspecified site
0.000 0.273 0.727
J14 Pneumonia due to Haemophilus influenzae
0.000 0.274 0.726
A30-A49 Other bacterial diseases
0.000 0.275 0.725
E66.8 Other obesity
0.000 0.278 0.722
J32 Chronic sinusitis
0.000 0.278 0.722
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.2 With renal complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
L40.8 Other psoriasis
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.3 Pustulosis palmaris et plantaris
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
L44 Other papulosquamous disorders
0.000 0.283 0.717
L41 Parapsoriasis
0.000 0.283 0.717
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
M12 Other specific arthropathies
0.000 0.285 0.715
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.285 0.715
M08 Juvenile arthritis
0.000 0.285 0.715
E06.9 Thyroiditis, unspecified
0.000 0.288 0.712
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.288 0.712
B20-B24 Human immunodeficiency virus [HIV] disease
0.000 0.288 0.712
E55 Vitamin D deficiency
0.000 0.289 0.710
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.290 0.710
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.293 0.706
L58 Radiodermatitis
0.000 0.293 0.706
L55 Sunburn
0.000 0.293 0.706
E40-E46 Malnutrition
0.000 0.295 0.705
B25 Cytomegaloviral disease
0.000 0.295 0.705
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.296 0.704
J35 Chronic diseases of tonsils and adenoids
0.000 0.297 0.703
J44 Other chronic obstructive pulmonary disease
0.000 0.298 0.702
M34 Systemic sclerosis
0.000 0.298 0.702
E10.8 With unspecified complications
0.000 0.300 0.700
M60-M63 Disorders of muscles
0.000 0.300 0.700
M06.3 Rheumatoid nodule
0.000 0.300 0.699
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.301 0.699
L57.5 Actinic granuloma
0.000 0.301 0.699
L57.4 Cutis laxa senilis
0.000 0.301 0.699
L57.3 Poikiloderma of Civatte
0.000 0.301 0.699
L57.2 Cutis rhomboidalis nuchae
0.000 0.301 0.699
L57.1 Actinic reticuloid
0.000 0.301 0.699
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.000 0.301 0.699
L20 Atopic dermatitis
0.000 0.302 0.698
M07.6 Other enteropathic arthropathies
0.000 0.303 0.697
M07.5 Arthropathy in ulcerative colitis
0.000 0.303 0.697
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.303 0.697
M07.2 Psoriatic spondylitis
0.000 0.303 0.697
M07.1 Arthritis mutilans
0.000 0.303 0.697
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.303 0.697
L10-L14 Bullous disorders
0.000 0.303 0.697
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.304 0.696
L25 Unspecified contact dermatitis
0.000 0.304 0.696
L24 Irritant contact dermatitis
0.000 0.304 0.696
L23 Allergic contact dermatitis
0.000 0.304 0.696
L21 Seborrhoeic dermatitis
0.000 0.304 0.696
L26 Exfoliative dermatitis
0.000 0.304 0.696
L22 Diaper [napkin] dermatitis
0.000 0.304 0.696
J11 Influenza, virus not identified
0.000 0.305 0.695
Chapter XXII Codes for special purposes
0.000 0.305 0.694
B49 Unspecified mycosis
0.000 0.306 0.694
D52 Folate deficiency anaemia
0.000 0.307 0.693
D68.5 Primary Thrombophilia
0.000 0.309 0.691
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.311 0.689
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.311 0.689
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.311 0.689
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.311 0.689
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.311 0.689
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.311 0.689
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.311 0.689
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.311 0.689
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.315 0.685
M07.38 Other psoriatic arthropathies (Other)
0.000 0.315 0.685
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.315 0.685
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.315 0.685
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.315 0.685
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.315 0.685
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.315 0.685
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.315 0.685
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.315 0.685
E05.5 Thyroid crisis or storm
0.000 0.316 0.684
E05.4 Thyrotoxicosis factitia
0.000 0.316 0.684
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.316 0.684
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.316 0.684
J35.0 Chronic tonsillitis
0.000 0.317 0.683
L29.2 Pruritus vulvae
0.000 0.317 0.683
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.318 0.682
E13 Other specified diabetes mellitus
0.000 0.319 0.681
L04 Acute lymphadenitis
0.000 0.321 0.679
L01 Impetigo
0.000 0.321 0.679
L00 Staphylococcal scalded skin syndrome
0.000 0.321 0.679
L29.8 Other pruritus
0.000 0.322 0.678
L29.3 Anogenital pruritus, unspecified
0.000 0.322 0.678
L29.1 Pruritus scroti
0.000 0.322 0.678
M80-M85 Disorders of bone density and structure
0.000 0.323 0.677
L92 Granulomatous disorders of skin and subcutaneous tissue
0.000 0.325 0.675
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.327 0.673
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.000 0.327 0.673
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.328 0.671
B99-B99 Other infectious diseases
0.000 0.329 0.671
E53.8 Deficiency of other specified B group vitamins
0.000 0.331 0.669
J15 Bacterial pneumonia, not elsewhere classified
0.000 0.332 0.668
B85-B89 Pediculosis, acariasis and other infestations
0.000 0.333 0.667
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.000 0.333 0.667
A75-A79 Rickettsioses
0.000 0.333 0.667
A70-A74 Other diseases caused by chlamydiae
0.000 0.333 0.667
A65-A69 Other spirochaetal diseases
0.000 0.333 0.667
A20-A28 Certain zoonotic bacterial diseases
0.000 0.333 0.667
E14 Unspecified diabetes mellitus
0.000 0.334 0.666
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.000 0.334 0.666
E06.5 Other chronic thyroiditis
0.000 0.336 0.664
E06.4 Drug-induced thyroiditis
0.000 0.336 0.664
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.336 0.664
E06.1 Subacute thyroiditis
0.000 0.336 0.664
E06.0 Acute thyroiditis
0.000 0.336 0.664
D66 Hereditary factor VIII deficiency
0.000 0.336 0.664
A80-A89 Viral infections of the central nervous system
0.000 0.337 0.662
J40 Bronchitis, not specified as acute or chronic
0.000 0.338 0.662
D68.8 Other specified coagulation defects
0.000 0.338 0.662
M05.8 Other seropositive rheumatoid arthritis
0.000 0.339 0.661
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.339 0.661
M05.2 Rheumatoid vasculitis
0.000 0.339 0.661
M05.1 Rheumatoid lung disease
0.000 0.339 0.661
M05.0 Felty's syndrome
0.000 0.339 0.661
J32.8 Other chronic sinusitis
0.000 0.339 0.661
M11 Other crystal arthropathies
0.000 0.339 0.660
M35.7 Hypermobility syndrome
0.000 0.340 0.660
L05 Pilonidal cyst
0.000 0.341 0.659
L08.1 Erythrasma
0.000 0.341 0.658
L08.0 Pyoderma
0.000 0.341 0.658
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.000 0.342 0.658
J09 Influenza due to certain identified influenza virus
0.000 0.342 0.658
J10.1 Influenza with other respiratory manifestations, influenza virus identified
0.000 0.343 0.657
J84 Other interstitial pulmonary diseases
0.000 0.343 0.657
M31 Other necrotising vasculopathies
0.000 0.344 0.656
L27.0 Generalised skin eruption due to drugs and medicaments
0.000 0.344 0.656
M10 Gout
0.000 0.344 0.656
B65-B83 Helminthiases
0.000 0.345 0.655
E27.8 Other specified disorders of adrenal gland
0.000 0.346 0.654
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.346 0.654
L42 Pityriasis rosea
0.000 0.347 0.652
B48 Other mycoses, not elsewhere classified
0.000 0.349 0.651
B47 Mycetoma
0.000 0.349 0.651
B46 Zygomycosis
0.000 0.349 0.651
B45 Cryptococcosis
0.000 0.349 0.651
B43 Chromomycosis and phaeomycotic abscess
0.000 0.349 0.651
B42 Sporotrichosis
0.000 0.349 0.651
B41 Paracoccidioidomycosis
0.000 0.349 0.651
B40 Blastomycosis
0.000 0.349 0.651
B39 Histoplasmosis
0.000 0.349 0.651
B38 Coccidioidomycosis
0.000 0.349 0.651
B36 Other superficial mycoses
0.000 0.349 0.651
E11 Non-insulin-dependent diabetes mellitus
0.000 0.349 0.651
M80 Osteoporosis with pathological fracture
0.000 0.349 0.651
D64.8 Other specified anaemias
0.000 0.350 0.650
D64.4 Congenital dyserythropoietic anaemia
0.000 0.350 0.650
D64.3 Other sideroblastic anaemias
0.000 0.350 0.650
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.350 0.650
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.350 0.650
D64.0 Hereditary sideroblastic anaemia
0.000 0.350 0.650
E03.8 Other specified hypothyroidism
0.000 0.351 0.649
M91-M94 Chondropathies
0.000 0.355 0.645
B37.7 Candidal septicaemia
0.000 0.357 0.643
B37.6 Candidal endocarditis
0.000 0.357 0.643
B37.5 Candidal meningitis
0.000 0.357 0.643
B37.2 Candidiasis of skin and nail
0.000 0.357 0.643
B37.1 Pulmonary candidiasis
0.000 0.357 0.643
M00-M03 Infectious arthropathies
0.000 0.358 0.642
J82 Pulmonary eosinophilia, not elsewhere classified
0.000 0.358 0.642
L08.8 Other specified local infections of skin and subcutaneous tissue
0.000 0.358 0.642
A49 Bacterial infection of unspecified site
0.000 0.359 0.641
D61.8 Other specified aplastic anaemias
0.000 0.359 0.641
D61.3 Idiopathic aplastic anaemia
0.000 0.359 0.641
D61.2 Aplastic anaemia due to other external agents
0.000 0.359 0.641
D61.1 Drug-induced aplastic anaemia
0.000 0.359 0.641
D61.0 Constitutional aplastic anaemia
0.000 0.359 0.641
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.359 0.641
B34.9 Viral infection, unspecified
0.000 0.359 0.641
J46 Status asthmaticus
0.000 0.360 0.640
J17 Pneumonia in diseases classified elsewhere
0.000 0.360 0.639
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.361 0.639
A15-A19 Tuberculosis
0.000 0.362 0.638
L82 Seborrhoeic keratosis
0.000 0.365 0.635
J18.2 Hypostatic pneumonia, unspecified
0.000 0.366 0.634
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.000 0.368 0.632
D67 Hereditary factor IX deficiency
0.000 0.368 0.632
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.368 0.632
L83 Acanthosis nigricans
0.000 0.368 0.632
E73 Lactose intolerance
0.000 0.369 0.631
B35 Dermatophytosis
0.000 0.371 0.628
M80.9 Unspecified osteoporosis with pathological fracture
0.000 0.372 0.628
M22 Disorders of patella
0.000 0.372 0.628
J22 Unspecified acute lower respiratory infection
0.000 0.373 0.627
J00-J06 Acute upper respiratory infections
0.000 0.373 0.627
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.000 0.373 0.627
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.374 0.626
M14.6 Neuropathic arthropathy
0.000 0.374 0.626
D86.0 Sarcoidosis of lung
0.000 0.375 0.625
J32.9 Chronic sinusitis, unspecified
0.000 0.375 0.625
D86.9 Sarcoidosis, unspecified
0.000 0.377 0.623
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.377 0.623
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.377 0.623
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.377 0.623
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.377 0.623
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.377 0.623
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.377 0.623
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.377 0.623
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.377 0.623
D53 Other nutritional anaemias
0.000 0.378 0.622
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.378 0.621
E63 Other nutritional deficiencies
0.000 0.378 0.621
E56 Other vitamin deficiencies
0.000 0.378 0.621
E51 Thiamine deficiency
0.000 0.378 0.621
E50 Vitamin A deficiency
0.000 0.378 0.621
E60 Dietary zinc deficiency
0.000 0.378 0.621
E59 Dietary selenium deficiency
0.000 0.378 0.621
E58 Dietary calcium deficiency
0.000 0.378 0.621
E54 Ascorbic acid deficiency
0.000 0.378 0.621
E52 Niacin deficiency [pellagra]
0.000 0.378 0.621
B50-B64 Protozoal diseases
0.000 0.381 0.618
J41 Simple and mucopurulent chronic bronchitis
0.000 0.384 0.616
D68.6 Other Thrombophilia
0.000 0.384 0.615
M34.9 Systemic sclerosis, unspecified
0.000 0.389 0.611
M35.0 Sicca syndrome [Sjogren]
0.000 0.389 0.611
B90-B94 Sequelae of infectious and parasitic diseases
0.000 0.390 0.610
M06.4 Inflammatory polyarthropathy
0.000 0.391 0.609
E26 Hyperaldosteronism
0.000 0.391 0.609
B25.9 Cytomegaloviral disease, unspecified
0.000 0.392 0.608
E67 Other hyperalimentation
0.000 0.396 0.603
E68 Sequelae of hyperalimentation
0.000 0.396 0.603
D50.1 Sideropenic dysphagia
0.000 0.397 0.603
B33 Other viral diseases, not elsewhere classified
0.000 0.397 0.603
B30 Viral conjunctivitis
0.000 0.397 0.603
B27 Infectious mononucleosis
0.000 0.397 0.603
B26 Mumps
0.000 0.397 0.603
E87.1 Hypo-osmolality and hyponatraemia
0.000 0.398 0.602
E55.9 Vitamin D deficiency, unspecified
0.000 0.402 0.598
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.402 0.598
E84 Cystic fibrosis
0.000 0.404 0.596
E79 Disorders of purine and pyrimidine metabolism
0.000 0.404 0.596
E77 Disorders of glycoprotein metabolism
0.000 0.404 0.596
E76 Disorders of glycosaminoglycan metabolism
0.000 0.404 0.596
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.404 0.596
E72 Other disorders of amino-acid metabolism
0.000 0.404 0.596
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.404 0.596
E70 Disorders of aromatic amino-acid metabolism
0.000 0.404 0.596
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.404 0.596
E74 Other disorders of carbohydrate metabolism
0.000 0.405 0.595
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.406 0.594
M35.8 Other specified systemic involvement of connective tissue
0.000 0.406 0.594
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.406 0.594
M35.5 Multifocal fibrosclerosis
0.000 0.406 0.594
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.406 0.594
M35.2 Behcet's disease
0.000 0.406 0.594
M35.1 Other overlap syndromes
0.000 0.406 0.594
D68.4 Acquired coagulation factor deficiency
0.000 0.406 0.593
D68.1 Hereditary factor XI deficiency
0.000 0.406 0.593
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.407 0.593
M32 Systemic lupus erythematosus
0.000 0.407 0.593
D68.0 Von Willebrand's disease
0.000 0.407 0.593
D84 Other immunodeficiencies
0.000 0.407 0.593
D83 Common variable immunodeficiency
0.000 0.407 0.593
D82 Immunodeficiency associated with other major defects
0.000 0.407 0.593
D81 Combined immunodeficiencies
0.000 0.407 0.593
M31.3 Wegener's granulomatosis
0.000 0.408 0.592
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.409 0.591
E80.4 Gilbert's syndrome
0.000 0.409 0.591
L30 Other dermatitis
0.000 0.410 0.590
D62 Acute posthaemorrhagic anaemia
0.000 0.411 0.589
A63.0 Anogenital (venereal) warts
0.000 0.413 0.587
E27.9 Disorder of adrenal gland, unspecified
0.000 0.413 0.587
L89 Decubitus ulcer
0.000 0.414 0.586
D51 Vitamin B12 deficiency anaemia
0.000 0.416 0.584
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)
0.000 0.419 0.581
M33 Dermatopolymyositis
0.000 0.419 0.581
E65 Localised adiposity
0.000 0.421 0.579
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.422 0.577
E32 Diseases of thymus
0.000 0.422 0.577
E31 Polyglandular dysfunction
0.000 0.422 0.577
E30 Disorders of puberty, not elsewhere classified
0.000 0.422 0.577
E25 Adrenogenital disorders
0.000 0.422 0.577
E20 Hypoparathyroidism
0.000 0.422 0.577
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.000 0.423 0.577
M30 Polyarteritis nodosa and related conditions
0.000 0.424 0.576
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.426 0.574
E11.3 With ophthalmic complications
0.000 0.426 0.574
J42 Unspecified chronic bronchitis
0.000 0.427 0.573
L43.9 Lichen planus, unspecified
0.000 0.429 0.571
D59 Acquired haemolytic anaemia
0.000 0.429 0.571
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.431 0.569
E04.2 Non-toxic multinodular goitre
0.000 0.432 0.568
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.433 0.567
J12 Viral pneumonia, not elsewhere classified
0.000 0.434 0.566
E28 Ovarian dysfunction
0.000 0.434 0.566
J20 Acute bronchitis
0.000 0.434 0.565
E89.0 Postprocedural hypothyroidism
0.000 0.435 0.565
E27.5 Adrenomedullary hyperfunction
0.000 0.435 0.565
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.435 0.565
E27.2 Addisonian crisis
0.000 0.435 0.565
E27.0 Other adrenocortical overactivity
0.000 0.435 0.565
E05.8 Other thyrotoxicosis
0.000 0.435 0.565
J33 Nasal polyp
0.000 0.436 0.564
M80.98 Unspecified osteoporosis with pathological fracture (Other)
0.000 0.436 0.564
J32.0 Chronic maxillary sinusitis
0.000 0.438 0.561
M14.8 Arthropathies in other specified diseases classified elsewhere
0.000 0.440 0.560
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.440 0.560
M14.4 Arthropathy in amyloidosis
0.000 0.440 0.560
M14.3 Lipoid dermatoarthritis
0.000 0.440 0.560
M14.2 Diabetic arthropathy
0.000 0.440 0.560
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.440 0.560
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.440 0.560
B37.4 Candidiasis of other urogenital sites
0.000 0.440 0.560
L28.0 Lichen simplex chronicus
0.000 0.440 0.560
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.441 0.559
A60 Anogenital herpesviral [herpes simplex] infections
0.000 0.443 0.557
A59 Trichomoniasis
0.000 0.443 0.557
A56 Other sexually transmitted chlamydial diseases
0.000 0.443 0.557
A54 Gonococcal infection
0.000 0.443 0.557
A53 Other and unspecified syphilis
0.000 0.443 0.557
A52 Late syphilis
0.000 0.443 0.557
A51 Early syphilis
0.000 0.443 0.557
A50 Congenital syphilis
0.000 0.443 0.557
A64 Unspecified sexually transmitted disease
0.000 0.443 0.557
A58 Granuloma inguinale
0.000 0.443 0.557
A57 Chancroid
0.000 0.443 0.557
A55 Chlamydial lymphogranuloma (venereum)
0.000 0.443 0.557
B24 Unspecified human immunodeficiency virus [HIV] disease
0.000 0.445 0.555
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites
0.000 0.445 0.555
B15-B19 Viral hepatitis
0.000 0.449 0.550
J18.0 Bronchopneumonia, unspecified
0.000 0.450 0.550
L93 Lupus erythematosus
0.000 0.450 0.550
L27.9 Dermatitis due to unspecified substance taken internally
0.000 0.450 0.550
L27.8 Dermatitis due to other substances taken internally
0.000 0.450 0.550
L27.2 Dermatitis due to ingested food
0.000 0.450 0.550
D80 Immunodeficiency with predominantly antibody defects
0.000 0.450 0.550
E07 Other disorders of thyroid
0.000 0.451 0.549
J10.8 Influenza with other manifestations, influenza virus identified
0.000 0.451 0.549
J10.0 Influenza with pneumonia, influenza virus identified
0.000 0.451 0.549
E61 Deficiency of other nutrient elements
0.000 0.451 0.549
E88 Other metabolic disorders
0.000 0.451 0.549
E87.2 Acidosis
0.000 0.453 0.547
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.453 0.547
A00-A09 Intestinal infectious diseases
0.000 0.453 0.547
A49.0 Staphylococcal infection, unspecified
0.000 0.454 0.546
J35.9 Chronic disease of tonsils and adenoids, unspecified
0.000 0.454 0.546
D52.9 Folate deficiency anaemia, unspecified
0.000 0.454 0.545
J21 Acute bronchiolitis
0.000 0.455 0.545
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.000 0.459 0.541
L87 Transepidermal elimination disorders
0.000 0.459 0.541
L88 Pyoderma gangrenosum
0.000 0.459 0.541
L86 Keratoderma in diseases classified elsewhere
0.000 0.459 0.541
L80 Vitiligo
0.000 0.459 0.541
B44 Aspergillosis
0.000 0.459 0.541
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.459 0.541
L94 Other localised connective tissue disorders
0.000 0.460 0.540
E04.1 Non-toxic single thyroid nodule
0.000 0.461 0.539
E53.9 Vitamin B deficiency, unspecified
0.000 0.461 0.539
E53.1 Pyridoxine deficiency
0.000 0.461 0.539
E53.0 Riboflavin deficiency
0.000 0.461 0.539
L43.8 Other lichen planus
0.000 0.462 0.538
L43.3 Subacute (active) lichen planus
0.000 0.462 0.538
L43.2 Lichenoid drug reaction
0.000 0.462 0.538
L43.1 Bullous lichen planus
0.000 0.462 0.538
L43.0 Hypertrophic lichen planus
0.000 0.462 0.538
E66.0 Obesity due to excess calories
0.000 0.463 0.537
E29 Testicular dysfunction
0.000 0.463 0.537
J11.1 Influenza with other respiratory manifestations, virus not identified
0.000 0.465 0.535
D86.8 Sarcoidosis of other and combined sites
0.000 0.466 0.534
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.000 0.467 0.533
E04.8 Other specified non-toxic goitre
0.000 0.467 0.533
E04.0 Non-toxic diffuse goitre
0.000 0.467 0.533
B34.8 Other viral infections of unspecified site
0.000 0.468 0.531
M13 Other arthritis
0.000 0.468 0.531
J18.8 Other pneumonia, organism unspecified
0.000 0.469 0.531

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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