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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs6916742
log Bayes Factor = 323.838
Chromosome 6   position 32,453,191  (GRCh37) Explore rs6916742 on Ensembl!
Variant rs6916742 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
1.000 0.000 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
1.000 0.000 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
1.000 0.000 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
E10.1 With ketoacidosis
1.000 0.000 0.000
E11.9 Without complications
1.000 0.000 0.000
E16.2 Hypoglycaemia, unspecified
1.000 0.000 0.000
H36.0 Diabetic retinopathy
1.000 0.000 0.000
J33.9 Nasal polyp, unspecified
1.000 0.000 0.000
J45.9 Asthma, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
1.000 0.000 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
1.000 0.000 0.000
E14 Unspecified diabetes mellitus
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
G35 Multiple sclerosis
0.000 0.000 1.000
J33 Nasal polyp
1.000 0.000 0.000
J44 Other chronic obstructive pulmonary disease
1.000 0.000 0.000
M06 Other rheumatoid arthritis
1.000 0.000 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
J40-J47 Chronic lower respiratory diseases
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
M05 Seropositive rheumatoid arthritis
1.000 0.000 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
1.000 0.000 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
J30-J39 Other diseases of upper respiratory tract
1.000 0.000 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
1.000 0.000 0.000
E10.4 With neurological complications
1.000 0.000 0.000
E16 Other disorders of pancreatic internal secretion
1.000 0.000 0.000
J45 Asthma
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
1.000 0.000 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
1.000 0.000 0.000
M35.3 Polymyalgia rheumatica
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
E14.3 With ophthalmic complications
1.000 0.000 0.000
K70-K77 Diseases of liver
1.000 0.000 0.000
M35 Other systemic involvement of connective tissue
1.000 0.000 0.000
J32 Chronic sinusitis
1.000 0.000 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.999 0.001 0.000
J33.8 Other polyp of sinus
0.999 0.001 0.000
M06.0 Seronegative rheumatoid arthritis
0.999 0.001 0.000
J46 Status asthmaticus
0.999 0.001 0.000
L40-L45 Papulosquamous disorders
0.999 0.001 0.000
Chapter XI Diseases of the digestive system
0.999 0.001 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.999 0.001 0.000
J32.9 Chronic sinusitis, unspecified
0.999 0.001 0.000
K51.9 Ulcerative colitis, unspecified
0.000 0.002 0.998
J33.0 Polyp of nasal cavity
0.998 0.002 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.998 0.002 0.000
L43 Lichen planus
0.998 0.002 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.998 0.002 0.000
K90 Intestinal malabsorption
0.997 0.003 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.997 0.003 0.000
L43.9 Lichen planus, unspecified
0.997 0.003 0.000
K90-K93 Other diseases of the digestive system
0.997 0.003 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.997 0.003 0.000
M06.3 Rheumatoid nodule
0.997 0.003 0.000
E10.5 With peripheral circulatory complications
0.996 0.004 0.000
E11.3 With ophthalmic complications
0.996 0.004 0.000
E14.9 Without complications
0.995 0.005 0.000
K74 Fibrosis and cirrhosis of liver
0.994 0.006 0.000
L40 Psoriasis
0.993 0.007 0.000
M31 Other necrotising vasculopathies
0.992 0.008 0.000
E10.2 With renal complications
0.992 0.008 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.991 0.009 0.000
C83.3 Large cell (diffuse)
0.991 0.009 0.000
M25.46 Effusion of joint (Lower leg)
0.989 0.011 0.000
K74.3 Primary biliary cirrhosis
0.989 0.011 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.989 0.011 0.000
M25.4 Effusion of joint
0.989 0.011 0.000
M25 Other joint disorders, not elsewhere classified
0.988 0.012 0.000
K51 Ulcerative colitis
0.000 0.013 0.987
M31.6 Other giant cell arteritis
0.987 0.013 0.000
E11.1 With ketoacidosis
0.984 0.016 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.983 0.017 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.982 0.018 0.000
L40.9 Psoriasis, unspecified
0.980 0.020 0.000
C91 Lymphoid leukaemia
0.980 0.020 0.000
C09 Malignant neoplasm of tonsil
0.980 0.020 0.000
K75 Other inflammatory liver diseases
0.980 0.020 0.000
Chapter VIII Diseases of the ear and mastoid process
0.979 0.021 0.000
C02.1 Border of tongue
0.977 0.023 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.977 0.023 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.973 0.027 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.971 0.029 0.000
H90-H95 Other disorders of ear
0.969 0.031 0.000
C09.9 Tonsil, unspecified
0.969 0.031 0.000
H91 Other hearing loss
0.968 0.032 0.000
H91.9 Hearing loss, unspecified
0.968 0.032 0.000
K75.4 Autoimmune hepatitis
0.968 0.032 0.000
L40.5 Arthropathic psoriasis
0.967 0.033 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.000 0.036 0.964
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.963 0.037 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.961 0.039 0.000
C02.9 Tongue, unspecified
0.960 0.040 0.000
J43 Emphysema
0.958 0.042 0.000
E11.5 With peripheral circulatory complications
0.957 0.043 0.000
M06.34 Rheumatoid nodule (Hand)
0.956 0.044 0.000
E10.8 With unspecified complications
0.956 0.044 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.003 0.045 0.951
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.954 0.046 0.000
E06 Thyroiditis
0.950 0.050 0.000
E10.6 With other specified complications
0.950 0.050 0.000
J86 Pyothorax
0.948 0.052 0.000
C91.1 Chronic lymphocytic leukaemia
0.945 0.055 0.000
D86.0 Sarcoidosis of lung
0.000 0.057 0.943
G37 Other demyelinating diseases of central nervous system
0.001 0.058 0.941
K73 Chronic hepatitis, not elsewhere classified
0.935 0.065 0.000
E06.3 Autoimmune thyroiditis
0.933 0.067 0.000
K72 Hepatic failure, not elsewhere classified
0.932 0.068 0.000
M65-M68 Disorders of synovium and tendon
0.927 0.073 0.000
E10.0 With coma
0.926 0.074 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.074 0.925
M06.98 Rheumatoid arthritis, unspecified (Other)
0.921 0.079 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.921 0.079 0.000
D86 Sarcoidosis
0.003 0.080 0.916
H60-H62 Diseases of external ear
0.918 0.082 0.000
H36 Retinal disorders in diseases classified elsewhere
0.916 0.084 0.000
J32.4 Chronic pansinusitis
0.909 0.091 0.000
J43.9 Emphysema, unspecified
0.905 0.095 0.000
K76 Other diseases of liver
0.905 0.095 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.820 0.102 0.078
J86.0 Pyothorax with fistula
0.898 0.102 0.000
M34 Systemic sclerosis
0.897 0.103 0.000
M25.47 Effusion of joint (Ankle and foot)
0.895 0.105 0.000
K76.8 Other specified diseases of liver
0.893 0.107 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.893 0.107 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.891 0.109 0.000
C82.2 Large cell, follicular
0.890 0.110 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.882 0.118 0.000
M65 Synovitis and tenosynovitis
0.881 0.119 0.000
K74.5 Biliary cirrhosis, unspecified
0.879 0.121 0.000
D86.9 Sarcoidosis, unspecified
0.000 0.126 0.874
M14 Arthropathies in other diseases classified elsewhere
0.872 0.128 0.000
M25.40 Effusion of joint (Multiple sites)
0.868 0.132 0.000
E14.1 With ketoacidosis
0.866 0.134 0.000
E11.8 With unspecified complications
0.866 0.134 0.000
E14.6 With other specified complications
0.861 0.139 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.861 0.139 0.000
J86.9 Pyothorax without fistula
0.860 0.140 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.860 0.140 0.000
C04 Malignant neoplasm of floor of mouth
0.859 0.141 0.000
H30-H36 Disorders of choroid and retina
0.855 0.145 0.000
M05.8 Other seropositive rheumatoid arthritis
0.854 0.146 0.000
Chapter VII Diseases of the eye and adnexa
0.853 0.147 0.000
M60-M63 Disorders of muscles
0.851 0.149 0.000
C01 Malignant neoplasm of base of tongue
0.849 0.151 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.848 0.152 0.000
M06.4 Inflammatory polyarthropathy
0.846 0.154 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.844 0.156 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.841 0.159 0.000
K51.5 Mucosal proctocolitis
0.000 0.160 0.840
E10.7 With multiple complications
0.840 0.160 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.836 0.164 0.000
K72.9 Hepatic failure, unspecified
0.834 0.166 0.000
E11.4 With neurological complications
0.833 0.167 0.000
E14.5 With peripheral circulatory complications
0.830 0.169 0.000
D64.9 Anaemia, unspecified
0.830 0.170 0.000
D60-D64 Aplastic and other anaemias
0.819 0.171 0.010
J32.2 Chronic ethmoidal sinusitis
0.827 0.173 0.000
D64 Other anaemias
0.822 0.174 0.004
M08 Juvenile arthritis
0.825 0.174 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.825 0.175 0.000
E05.9 Thyrotoxicosis, unspecified
0.824 0.176 0.000
M45-M49 Spondylopathies
0.824 0.176 0.000
H61 Other disorders of external ear
0.822 0.178 0.000
C91.5 Adult T-cell leukaemia
0.821 0.179 0.000
Q80-Q89 Other congenital malformations
0.820 0.180 0.000
E13 Other specified diabetes mellitus
0.820 0.180 0.000
C91.9 Lymphoid leukaemia, unspecified
0.819 0.181 0.000
E14.8 With unspecified complications
0.819 0.181 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.818 0.182 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.818 0.182 0.000
C82.0 Small cleaved cell, follicular
0.817 0.183 0.000
M07 Psoriatic and enteropathic arthropathies
0.817 0.183 0.000
C85.1 B-cell lymphoma, unspecified
0.815 0.185 0.000
E11.0 With coma
0.815 0.185 0.000
D86.1 Sarcoidosis of lymph nodes
0.001 0.185 0.813
M06.30 Rheumatoid nodule (Multiple sites)
0.814 0.186 0.000
K51.4 Pseudopolyposis of colon
0.000 0.187 0.813
L43.8 Other lichen planus
0.812 0.188 0.000
H40-H42 Glaucoma
0.810 0.190 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.807 0.193 0.000
K73.9 Chronic hepatitis, unspecified
0.807 0.193 0.000
C02.3 Anterior two-thirds of tongue, part unspecified
0.807 0.193 0.000
M05.1 Rheumatoid lung disease
0.807 0.193 0.000
C02.2 Ventral surface of tongue
0.806 0.194 0.000
E16.1 Other hypoglycaemia
0.806 0.194 0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.806 0.194 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.804 0.196 0.000
C03 Malignant neoplasm of gum
0.803 0.197 0.000
L50-L54 Urticaria and erythema
0.803 0.197 0.000
M06.8 Other specified rheumatoid arthritis
0.802 0.198 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.801 0.199 0.000
K51.2 Ulcerative (chronic) proctitis
0.000 0.199 0.801
C02.4 Lingual tonsil
0.799 0.201 0.000
K75.8 Other specified inflammatory liver diseases
0.798 0.202 0.000
L10-L14 Bullous disorders
0.796 0.204 0.000
M60 Myositis
0.795 0.205 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.795 0.205 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.794 0.206 0.000
H91.1 Presbycusis
0.794 0.206 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.793 0.206 0.000
C13 Malignant neoplasm of hypopharynx
0.792 0.208 0.000
M31.7 Microscopic polyangiitis
0.791 0.209 0.000
C07 Malignant neoplasm of parotid gland
0.790 0.210 0.000
C10 Malignant neoplasm of oropharynx
0.790 0.210 0.000
E07 Other disorders of thyroid
0.788 0.212 0.000
C91.0 Acute lymphoblastic leukaemia
0.787 0.213 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.786 0.214 0.000
C45 Mesothelioma
0.784 0.216 0.000
M66 Spontaneous rupture of synovium and tendon
0.783 0.217 0.000
E14.0 With coma
0.782 0.218 0.000
K51.8 Other ulcerative colitis
0.000 0.219 0.781
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.780 0.220 0.000
E14.4 With neurological complications
0.779 0.221 0.000
M06.33 Rheumatoid nodule (Forearm)
0.779 0.221 0.000
H40 Glaucoma
0.778 0.222 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.778 0.222 0.000
C82.3 Follicular lymphoma grade IIIa
0.777 0.223 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.777 0.223 0.000
E40-E46 Malnutrition
0.775 0.225 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.774 0.226 0.000
D80-D89 Certain disorders involving the immune mechanism
0.478 0.227 0.295
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.772 0.228 0.000
C83.1 Small cleaved cell (diffuse)
0.771 0.229 0.000
H40.9 Glaucoma, unspecified
0.770 0.230 0.000
Q83 Congenital malformations of breast
0.770 0.230 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.231 0.769
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.767 0.233 0.000
M45 Ankylosing spondylitis
0.767 0.233 0.000
H60 Otitis externa
0.766 0.234 0.000
M14.6 Neuropathic arthropathy
0.765 0.235 0.000
M31.8 Other specified necrotising vasculopathies
0.765 0.235 0.000
M30 Polyarteritis nodosa and related conditions
0.761 0.239 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.000 0.240 0.760
L43.0 Hypertrophic lichen planus
0.759 0.241 0.000
K72.0 Acute and subacute hepatic failure
0.759 0.241 0.000
L40.3 Pustulosis palmaris et plantaris
0.759 0.241 0.000
L44 Other papulosquamous disorders
0.758 0.242 0.000
C83.2 Mixed small and large cell (diffuse)
0.758 0.242 0.000
E11.7 With multiple complications
0.758 0.242 0.000
M34.8 Other forms of systemic sclerosis
0.757 0.243 0.000
C94 Other leukaemias of specified cell type
0.756 0.244 0.000
Q50-Q56 Congenital malformations of genital organs
0.756 0.244 0.000
C12 Malignant neoplasm of pyriform sinus
0.756 0.244 0.000
J43.2 Centrilobular emphysema
0.755 0.245 0.000
C05 Malignant neoplasm of palate
0.755 0.245 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.755 0.245 0.000
J32.1 Chronic frontal sinusitis
0.753 0.247 0.000
C82.4 Follicular lymphoma grade IIIb
0.752 0.247 0.000
C11 Malignant neoplasm of nasopharynx
0.751 0.249 0.000
M10 Gout
0.750 0.250 0.000
E11.6 With other specified complications
0.747 0.253 0.000
M34.1 CR(E)ST syndrome
0.747 0.253 0.000
J43.8 Other emphysema
0.747 0.253 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.256 0.744
M25.43 Effusion of joint (Forearm)
0.744 0.256 0.000
E14.2 Withrenal complications
0.744 0.256 0.000
M65.8 Other synovitis and tenosynovitis
0.744 0.256 0.000
K76.7 Hepatorenal syndrome
0.742 0.258 0.000
M12 Other specific arthropathies
0.741 0.259 0.000
M00-M03 Infectious arthropathies
0.741 0.259 0.000
H91.8 Other specified hearing loss
0.741 0.259 0.000
M60.0 Infective myositis
0.741 0.259 0.000
C04.9 Floor of mouth, unspecified
0.740 0.260 0.000
C02.8 Overlapping lesion of tongue
0.739 0.261 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.737 0.263 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.735 0.265 0.000
M06.04 Seronegative rheumatoid arthritis (Hand)
0.735 0.265 0.000
K72.1 Chronic hepatic failure
0.735 0.265 0.000
J45.1 Nonallergic asthma
0.733 0.267 0.000
J37 Chronic laryngitis and laryngotracheitis
0.733 0.267 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.731 0.269 0.000
H40.5 Glaucoma secondary to other eye disorders
0.731 0.269 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.730 0.270 0.000
M35.1 Other overlap syndromes
0.729 0.271 0.000
H61.0 Perichondritis of external ear
0.727 0.273 0.000
J41 Simple and mucopurulent chronic bronchitis
0.726 0.274 0.000
M14.2 Diabetic arthropathy
0.726 0.274 0.000
D86.8 Sarcoidosis of other and combined sites
0.002 0.275 0.723
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.723 0.277 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.720 0.280 0.000
M31.9 Necrotising vasculopathy, unspecified
0.719 0.281 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.718 0.282 0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.718 0.282 0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.718 0.282 0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.717 0.283 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.717 0.283 0.000
C82.6 Cutaneous follicle centre lymphoma
0.717 0.283 0.000
C82.5 Diffuse follicle centre lymphoma
0.717 0.283 0.000
E14.7 With multiple complications
0.717 0.283 0.000
M06.2 Rheumatoid bursitis
0.717 0.283 0.000
M06.1 Adult-onset Still's disease
0.717 0.283 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.717 0.283 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.717 0.283 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.717 0.283 0.000
E16.4 Abnormal secretion of gastrin
0.717 0.283 0.000
E16.3 Increased secretion of glucagon
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E15 Nondiabetic hypoglycaemic coma
0.717 0.283 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.717 0.283 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.717 0.283 0.000
M35.5 Multifocal fibrosclerosis
0.717 0.283 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.717 0.283 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.716 0.283 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.716 0.283 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.716 0.283 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.716 0.284 0.000
C02.0 Dorsal surface of tongue
0.716 0.284 0.000
J85 Abscess of lung and mediastinum
0.716 0.284 0.000
L43.3 Subacute (active) lichen planus
0.716 0.284 0.000
L43.2 Lichenoid drug reaction
0.716 0.284 0.000
L43.1 Bullous lichen planus
0.716 0.284 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.715 0.285 0.000
K90.3 Pancreatic steatorrhoea
0.715 0.285 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.715 0.285 0.000
K90.1 Tropical sprue
0.715 0.285 0.000
H91.0 Ototoxic hearing loss
0.715 0.285 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.715 0.285 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.714 0.285 0.000
M06.38 Rheumatoid nodule (Other)
0.714 0.285 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.714 0.285 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.714 0.285 0.000
K74.4 Secondary biliary cirrhosis
0.713 0.287 0.000
K74.2 Hepatic fibrosis with hepatic sclerosis
0.713 0.287 0.000
M05.0 Felty's syndrome
0.713 0.287 0.000
L40.2 Acrodermatitis continua
0.712 0.288 0.000
M46 Other inflammatory spondylopathies
0.711 0.289 0.000
M31.2 Lethal midline granuloma
0.711 0.289 0.000
H43-H45 Disorders of vitreous body and globe
0.711 0.289 0.000
C83.6 Undifferentiated (diffuse)
0.710 0.289 0.000
C83.5 Lymphoblastic (diffuse)
0.710 0.289 0.000
C83.4 Immunoblastic (diffuse)
0.710 0.289 0.000
J33.1 Polypoid sinus degeneration
0.710 0.290 0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.709 0.291 0.000
M25.49 Effusion of joint (Site unspecified)
0.709 0.291 0.000
M25.48 Effusion of joint (Other)
0.709 0.291 0.000
K73.8 Other chronic hepatitis, not elsewhere classified
0.709 0.291 0.000
C95 Leukaemia of unspecified cell type
0.708 0.291 0.000
M25.2 Flail joint
0.708 0.292 0.000
M25.1 Fistula of joint
0.708 0.292 0.000
M25.0 Haemarthrosis
0.707 0.293 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.706 0.293 0.000
K74.1 Hepatic sclerosis
0.704 0.296 0.000
M25.9 Joint disorder, unspecified
0.703 0.297 0.000
C91.8 Mature B-cell leukaemia Burkitt-type
0.703 0.297 0.000
C91.7 Other lymphoid leukaemia
0.703 0.297 0.000
C91.6 Prolymphocytic leukaemia of T-cell type
0.703 0.297 0.000
C91.3 Prolymphocytic leukaemia
0.703 0.297 0.000
C91.2 Subacute lymphocytic leukaemia
0.703 0.297 0.000
C09.8 Overlapping lesion of tonsil
0.702 0.297 0.000
K75.2 Nonspecific reactive hepatitis
0.702 0.298 0.000
K75.1 Phlebitis of portal vein
0.702 0.298 0.000
Q54 Hypospadias
0.702 0.298 0.000
C09.0 Tonsillar fossa
0.702 0.298 0.000
Q85 Phakomatoses, not elsewhere classified
0.700 0.300 0.000
L51 Erythema multiforme
0.698 0.301 0.000
C85.0 Lymphosarcoma
0.697 0.302 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.697 0.303 0.000
J45.8 Mixed asthma
0.697 0.303 0.000
L40.4 Guttate psoriasis
0.697 0.303 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.696 0.304 0.000
J45.0 Predominantly allergic asthma
0.696 0.304 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.002 0.304 0.693
H94 Other disorders of ear in diseases classified elsewhere
0.695 0.305 0.000
E03.1 Congenital hypothyroidism without goitre
0.694 0.306 0.000
M07.3 Other psoriatic arthropathies
0.693 0.307 0.000
E78.5 Hyperlipidaemia, unspecified
0.692 0.308 0.000
M11 Other crystal arthropathies
0.692 0.308 0.000
L40.1 Generalised pustular psoriasis
0.689 0.310 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.689 0.311 0.000
K71 Toxic liver disease
0.688 0.312 0.000
E03.8 Other specified hypothyroidism
0.687 0.313 0.000
L52 Erythema nodosum
0.687 0.313 0.000
J43.1 Panlobular emphysema
0.687 0.313 0.000
J43.0 MacLeod's syndrome
0.687 0.313 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.685 0.315 0.000
E70-E90 Metabolic disorders
0.685 0.315 0.000
J32.8 Other chronic sinusitis
0.685 0.315 0.000
E50-E64 Other nutritional deficiencies
0.685 0.315 0.000
L41 Parapsoriasis
0.684 0.316 0.000
M08.0 Juvenile rheumatoid arthritis
0.684 0.316 0.000
C45.9 Mesothelioma, unspecified
0.682 0.318 0.000
E06.4 Drug-induced thyroiditis
0.681 0.319 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.681 0.319 0.000
E06.0 Acute thyroiditis
0.681 0.319 0.000
K74.6 Other and unspecified cirrhosis of liver
0.681 0.319 0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.680 0.320 0.000
K77 Liver disorders in diseases classified elsewhere
0.679 0.321 0.000
M34.0 Progressive systemic sclerosis
0.678 0.322 0.000
C74 Malignant neoplasm of adrenal gland
0.677 0.323 0.000
C60-C63 Malignant neoplasms of male genital organs
0.676 0.324 0.000
G37.5 Concentric sclerosis [Balo]
0.001 0.325 0.675
G37.4 Subacute necrotising myelitis
0.001 0.325 0.675
G37.2 Central pontine myelinolysis
0.001 0.325 0.675
G37.1 Central demyelination of corpus callosum
0.001 0.325 0.675
G37.0 Diffuse sclerosis
0.001 0.325 0.675
M13 Other arthritis
0.675 0.325 0.000
M25.41 Effusion of joint (Shoulder region)
0.673 0.327 0.000
Q83.1 Accessory breast
0.673 0.327 0.000
Q82 Other congenital malformations of skin
0.673 0.327 0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.671 0.329 0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.671 0.329 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.670 0.329 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.670 0.330 0.000
H61.1 Non-infective disorders of pinna
0.670 0.330 0.000
M65.86 Other synovitis and tenosynovitis (Lower leg)
0.670 0.330 0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.670 0.330 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.667 0.332 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.667 0.333 0.000
M66.3 Spontaneous rupture of flexor tendons
0.667 0.333 0.000
G36 Other acute disseminated demyelination
0.003 0.334 0.664
M66.5 Spontaneous rupture of unspecified tendon
0.666 0.334 0.000
E13.3 With ophthalmic complications
0.665 0.334 0.000
K90.9 Intestinal malabsorption, unspecified
0.665 0.335 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.665 0.335 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.665 0.335 0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.664 0.336 0.000
C45.7 Mesothelioma of other sites
0.663 0.337 0.000
H92 Otalgia and effusion of ear
0.663 0.337 0.000
M60.05 Infective myositis (Pelvic region and thigh)
0.662 0.338 0.000
D64.0 Hereditary sideroblastic anaemia
0.658 0.340 0.003
E06.9 Thyroiditis, unspecified
0.659 0.341 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.656 0.343 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.000 0.344 0.656
H40.3 Glaucoma secondary to eye trauma
0.655 0.345 0.000
H30 Chorioretinal inflammation
0.655 0.345 0.000
C84.0 Mycosis fungoides
0.655 0.345 0.000
M25.44 Effusion of joint (Hand)
0.654 0.346 0.000
M65.1 Other infective (teno)synovitis
0.654 0.346 0.000
K40-K46 Hernia
0.653 0.347 0.000
Q83.8 Other congenital malformations of breast
0.652 0.348 0.000
C04.0 Anterior floor of mouth
0.651 0.348 0.000
L12 Pemphigoid
0.651 0.349 0.000
L42 Pityriasis rosea
0.649 0.351 0.000
K76.5 Hepatic veno-occlusive disease
0.649 0.351 0.000
K76.4 Peliosis hepatis
0.649 0.351 0.000
K76.2 Central haemorrhagic necrosis of liver
0.649 0.351 0.000
C06.0 Cheek mucosa
0.647 0.353 0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.646 0.354 0.000
J95-J99 Other diseases of the respiratory system
0.645 0.355 0.000
E07.9 Disorder of thyroid, unspecified
0.645 0.355 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.644 0.356 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.643 0.356 0.000
Q35-Q37 Cleft lip and cleft palate
0.643 0.357 0.000
M60.9 Myositis, unspecified
0.643 0.357 0.000
H61.8 Other specified disorders of external ear
0.643 0.357 0.000
J32.0 Chronic maxillary sinusitis
0.642 0.358 0.000
L13 Other bullous disorders
0.640 0.360 0.000
H40.4 Glaucoma secondary to eye inflammation
0.640 0.360 0.000
C10.9 Oropharynx, unspecified
0.639 0.361 0.000
H25-H28 Disorders of lens
0.639 0.361 0.000
Q54.0 Hypospadias, balanic
0.639 0.361 0.000
H91.2 Sudden idiopathic hearing loss
0.638 0.362 0.000
M34.9 Systemic sclerosis, unspecified
0.638 0.362 0.000
K75.9 Inflammatory liver disease, unspecified
0.638 0.362 0.000
M05.19 Rheumatoid lung disease (Site unspecified)
0.638 0.362 0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.638 0.362 0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)
0.637 0.363 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.636 0.364 0.000
C45.0 Mesothelioma of pleura
0.636 0.364 0.000
H91.3 Deaf mutism, not elsewhere classified
0.636 0.364 0.000
M60.08 Infective myositis (Other)
0.635 0.365 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.635 0.365 0.000
M05.2 Rheumatoid vasculitis
0.635 0.365 0.000
H60.1 Cellulitis of external ear
0.635 0.365 0.000
K76.3 Infarction of liver
0.634 0.365 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.634 0.366 0.000
M35.7 Hypermobility syndrome
0.634 0.366 0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.633 0.367 0.000
M25.42 Effusion of joint (Upper arm)
0.633 0.367 0.000
C86 Other specified types of T/NK-cell lymphoma
0.631 0.369 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.631 0.369 0.000
C03.1 Lower gum
0.630 0.370 0.000
D62 Acute posthaemorrhagic anaemia
0.628 0.370 0.002
C03.0 Upper gum
0.627 0.372 0.000
J32.3 Chronic sphenoidal sinusitis
0.627 0.373 0.000
C00 Malignant neoplasm of lip
0.626 0.373 0.000
C40 Malignant neoplasm of bone and articular cartilage of limbs
0.626 0.374 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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