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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs6921256
log Bayes Factor = 54.7929
Chromosome 6   position 27,587,518  (GRCh37) Explore rs6921256 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
1.000 0.000 0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.000 0.001 0.999
E05.9 Thyrotoxicosis, unspecified
0.914 0.086 0.000
E10 Insulin-dependent diabetes mellitus
0.903 0.097 0.000
E10.9 Without complications
0.896 0.104 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.894 0.106 0.000
E00-E07 Disorders of thyroid gland
0.887 0.113 0.000
E03 Other hypothyroidism
0.878 0.122 0.000
E10-E14 Diabetes mellitus
0.877 0.123 0.000
E03.9 Hypothyroidism, unspecified
0.875 0.125 0.000
E10.4 With neurological complications
0.872 0.128 0.000
E10.3 With ophthalmic complications
0.864 0.136 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.863 0.137 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.775 0.225 0.000
E10.2 With renal complications
0.766 0.234 0.000
K90 Intestinal malabsorption
0.743 0.257 0.000
E10.7 With multiple complications
0.722 0.278 0.000
E16 Other disorders of pancreatic internal secretion
0.711 0.289 0.000
E10.6 With other specified complications
0.705 0.295 0.000
E07 Other disorders of thyroid
0.702 0.298 0.000
E14 Unspecified diabetes mellitus
0.687 0.313 0.000
K90.9 Intestinal malabsorption, unspecified
0.660 0.340 0.000
E16.2 Hypoglycaemia, unspecified
0.655 0.345 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.654 0.345 0.000
E05.5 Thyroid crisis or storm
0.641 0.359 0.000
E05.4 Thyrotoxicosis factitia
0.641 0.359 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.641 0.359 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.636 0.364 0.000
E00 Congenital iodine-deficiency syndrome
0.636 0.364 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.631 0.369 0.000
E05.8 Other thyrotoxicosis
0.631 0.369 0.000
E03.5 Myxoedema coma
0.630 0.370 0.000
E03.4 Atrophy of thyroid (acquired)
0.630 0.370 0.000
E03.3 Postinfectious hypothyroidism
0.630 0.370 0.000
E12 Malnutrition-related diabetes mellitus
0.629 0.371 0.000
E10.0 With coma
0.618 0.382 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.617 0.383 0.000
E03.1 Congenital hypothyroidism without goitre
0.593 0.407 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.582 0.417 0.000
E14.4 With neurological complications
0.581 0.418 0.000
E07.8 Other specified disorders of thyroid
0.580 0.420 0.000
E11 Non-insulin-dependent diabetes mellitus
0.575 0.425 0.000
K90.8 Other intestinal malabsorption
0.575 0.425 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.567 0.433 0.000
E10.5 With peripheral circulatory complications
0.567 0.433 0.000
E10.1 With ketoacidosis
0.562 0.438 0.000
K40 Inguinal hernia
0.000 0.441 0.559
E03.8 Other specified hypothyroidism
0.556 0.443 0.000
E15 Nondiabetic hypoglycaemic coma
0.555 0.444 0.000
E11.5 With peripheral circulatory complications
0.553 0.447 0.000
E11.3 With ophthalmic complications
0.550 0.450 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.547 0.453 0.000
E16.1 Other hypoglycaemia
0.539 0.461 0.000
E14.8 With unspecified complications
0.534 0.466 0.000
K90.3 Pancreatic steatorrhoea
0.533 0.467 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.533 0.467 0.000
K90.1 Tropical sprue
0.533 0.467 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.532 0.468 0.000
E14.3 With ophthalmic complications
0.527 0.473 0.000
E10.8 With unspecified complications
0.526 0.473 0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.000 0.474 0.526
E13 Other specified diabetes mellitus
0.526 0.474 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.521 0.479 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.510 0.490 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.510 0.490 0.000
E16.4 Abnormal secretion of gastrin
0.510 0.490 0.000
E16.3 Increased secretion of glucagon
0.510 0.490 0.000
E14.6 With other specified complications
0.505 0.495 0.000
E07.1 Dyshormogenetic goitre
0.503 0.497 0.000
E07.0 Hypersecretion of calcitonin
0.503 0.497 0.000
E20-E35 Disorders of other endocrine glands
0.499 0.501 0.000
E40-E46 Malnutrition
0.494 0.506 0.000
E14.7 With multiple complications
0.492 0.508 0.000
E14.0 With coma
0.492 0.508 0.000
E07.9 Disorder of thyroid, unspecified
0.486 0.514 0.000
E14.5 With peripheral circulatory complications
0.482 0.518 0.000
E14.2 Withrenal complications
0.475 0.524 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.456 0.544 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.456 0.544 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.456 0.544 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.456 0.544 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.456 0.544 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.456 0.544 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.456 0.544 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.456 0.544 0.000
E14.1 With ketoacidosis
0.453 0.547 0.000
E12.9 Without complications
0.451 0.549 0.000
E12.8 With unspecified complications
0.451 0.549 0.000
E12.7 With multiple complications
0.451 0.549 0.000
E12.6 With other specified complications
0.451 0.549 0.000
E12.5 With peripheral circulatory complications
0.451 0.549 0.000
E12.4 With neurological complications
0.451 0.549 0.000
E12.3 With ophthalmic complications
0.451 0.549 0.000
E12.2 With renal complications
0.451 0.549 0.000
E12.1 With ketoacidosis
0.451 0.549 0.000
E12.0 With coma
0.451 0.549 0.000
E11.7 With multiple complications
0.450 0.550 0.000
E20 Hypoparathyroidism
0.420 0.580 0.000
E23 Hypofunction and other disorders of pituitary gland
0.418 0.582 0.000
E28 Ovarian dysfunction
0.415 0.585 0.000
E50-E64 Other nutritional deficiencies
0.412 0.588 0.000
E11.6 With other specified complications
0.409 0.591 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.404 0.596 0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene
0.000 0.599 0.401
K40.1 Bilateral inguinal hernia, with gangrene
0.000 0.599 0.401
E13.3 With ophthalmic complications
0.398 0.602 0.000
E06 Thyroiditis
0.382 0.617 0.000
E11.1 With ketoacidosis
0.383 0.617 0.000
E24 Cushing's syndrome
0.381 0.619 0.000
E14.9 Without complications
0.381 0.619 0.000
E13.8 With unspecified complications
0.377 0.623 0.000
E13.7 With multiple complications
0.377 0.623 0.000
E13.6 With other specified complications
0.377 0.623 0.000
E13.5 With peripheral circulatory complications
0.377 0.623 0.000
E13.4 With neurological complications
0.377 0.623 0.000
E13.2 With renal complications
0.377 0.623 0.000
E13.1 With ketoacidosis
0.377 0.623 0.000
E13.0 With coma
0.377 0.623 0.000
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene
0.000 0.623 0.377
E11.0 With coma
0.372 0.628 0.000
E65-E68 Obesity and other hyperalimentation
0.368 0.631 0.000
E21.3 Hyperparathyroidism, unspecified
0.366 0.634 0.000
E20.9 Hypoparathyroidism, unspecified
0.364 0.636 0.000
E31 Polyglandular dysfunction
0.358 0.642 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.358 0.642 0.000
E32 Diseases of thymus
0.358 0.642 0.000
E30 Disorders of puberty, not elsewhere classified
0.358 0.642 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.354 0.646 0.000
E45 Retarded development following protein-energy malnutrition
0.354 0.646 0.000
E43 Unspecified severe protein-energy malnutrition
0.354 0.646 0.000
E42 Marasmic kwashiorkor
0.354 0.646 0.000
E41 Nutritional marasmus
0.354 0.646 0.000
E40 Kwashiorkor
0.354 0.646 0.000
E28.3 Primary ovarian failure
0.354 0.646 0.000
E23.7 Disorder of pituitary gland, unspecified
0.347 0.653 0.000
E23.0 Hypopituitarism
0.339 0.660 0.000
E25 Adrenogenital disorders
0.336 0.664 0.000
E21.4 Other specified disorders of parathyroid gland
0.322 0.678 0.000
E29 Testicular dysfunction
0.320 0.680 0.000
E54 Ascorbic acid deficiency
0.316 0.684 0.000
E23.2 Diabetes insipidus
0.311 0.689 0.000
E34 Other endocrine disorders
0.303 0.697 0.000
E20.8 Other hypoparathyroidism
0.301 0.699 0.000
E20.1 Pseudohypoparathyroidism
0.301 0.699 0.000
E20.0 Idiopathic hypoparathyroidism
0.301 0.699 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.300 0.700 0.000
E23.1 Drug-induced hypopituitarism
0.300 0.700 0.000
E28.2 Polycystic ovarian syndrome
0.298 0.702 0.000
E28.9 Ovarian dysfunction, unspecified
0.297 0.703 0.000
E28.8 Other ovarian dysfunction
0.297 0.703 0.000
E28.1 Androgen excess
0.297 0.703 0.000
E28.0 Oestrogen excess
0.297 0.703 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.295 0.705 0.000
E63 Other nutritional deficiencies
0.295 0.705 0.000
E50 Vitamin A deficiency
0.295 0.705 0.000
E60 Dietary zinc deficiency
0.295 0.705 0.000
E59 Dietary selenium deficiency
0.295 0.705 0.000
E52 Niacin deficiency [pellagra]
0.295 0.705 0.000
E24.0 Pituitary-dependent Cushing's disease
0.294 0.706 0.000
E21.2 Other hyperparathyroidism
0.293 0.707 0.000
E58 Dietary calcium deficiency
0.293 0.707 0.000
E24.8 Other Cushing's syndrome
0.292 0.708 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.290 0.710 0.000
E51 Thiamine deficiency
0.287 0.713 0.000
E06.1 Subacute thyroiditis
0.284 0.716 0.000
E53 Deficiency of other B group vitamins
0.276 0.723 0.000
E56 Other vitamin deficiencies
0.275 0.725 0.000
E06.4 Drug-induced thyroiditis
0.274 0.725 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.274 0.725 0.000
E06.0 Acute thyroiditis
0.274 0.725 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.274 0.726 0.000
E24.3 Ectopic ACTH syndrome
0.274 0.726 0.000
E24.1 Nelson's syndrome
0.274 0.726 0.000
E11.8 With unspecified complications
0.272 0.728 0.000
E24.2 Drug-induced Cushing's syndrome
0.268 0.732 0.000
E67 Other hyperalimentation
0.264 0.736 0.000
E68 Sequelae of hyperalimentation
0.264 0.736 0.000
E24.9 Cushing's syndrome, unspecified
0.263 0.737 0.000
E23.6 Other disorders of pituitary gland
0.259 0.741 0.000
E31.0 Autoimmune polyglandular failure
0.257 0.743 0.000
E55 Vitamin D deficiency
0.257 0.743 0.000
E06.5 Other chronic thyroiditis
0.257 0.743 0.000
E31.9 Polyglandular dysfunction, unspecified
0.257 0.743 0.000
E31.8 Other polyglandular dysfunction
0.257 0.743 0.000
E31.1 Polyglandular hyperfunction
0.257 0.743 0.000
E30.9 Disorder of puberty, unspecified
0.257 0.743 0.000
E30.8 Other disorders of puberty
0.257 0.743 0.000
E30.1 Precocious puberty
0.257 0.743 0.000
E30.0 Delayed puberty
0.257 0.743 0.000
E32.9 Disease of thymus, unspecified
0.257 0.743 0.000
E32.8 Other diseases of thymus
0.257 0.743 0.000
E32.1 Abscess of thymus
0.257 0.743 0.000
E32.0 Persistent hyperplasia of thymus
0.257 0.743 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.257 0.743 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.257 0.743 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.257 0.743 0.000
E26 Hyperaldosteronism
0.256 0.743 0.001
E44.1 Mild protein-energy malnutrition
0.254 0.746 0.000
E44.0 Moderate protein-energy malnutrition
0.254 0.746 0.000
E29.9 Testicular dysfunction, unspecified
0.251 0.749 0.000
E25.9 Adrenogenital disorder, unspecified
0.241 0.759 0.000
E25.8 Other adrenogenital disorders
0.241 0.759 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.234 0.766 0.000
E13.9 Without complications
0.232 0.768 0.000
E06.9 Thyroiditis, unspecified
0.230 0.769 0.000
E29.8 Other testicular dysfunction
0.229 0.771 0.000
E29.0 Testicular hyperfunction
0.229 0.771 0.000
E46 Unspecified protein-energy malnutrition
0.228 0.771 0.000
E65 Localised adiposity
0.227 0.772 0.000
E34.8 Other specified endocrine disorders
0.221 0.779 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.218 0.781 0.000
E34.5 Androgen resistance syndrome
0.217 0.783 0.000
E34.4 Constitutional tall stature
0.217 0.783 0.000
E34.3 Short stature, not elsewhere classified
0.217 0.783 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.217 0.783 0.000
E34.1 Other hypersecretion of intestinal hormones
0.217 0.783 0.000
E61 Deficiency of other nutrient elements
0.213 0.787 0.000
E21.0 Primary hyperparathyroidism
0.213 0.787 0.000
E50.9 Vitamin A deficiency, unspecified
0.212 0.788 0.000
E50.8 Other manifestations of vitamin A deficiency
0.212 0.788 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.212 0.788 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.212 0.788 0.000
E50.5 Vitamin A deficiency with night blindness
0.212 0.788 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.212 0.788 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.212 0.788 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.212 0.788 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.212 0.788 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.212 0.788 0.000
E63.9 Nutritional deficiency, unspecified
0.212 0.788 0.000
E63.8 Other specified nutritional deficiencies
0.212 0.788 0.000
E63.1 Imbalance of constituents of food intake
0.212 0.788 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.212 0.788 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.212 0.788 0.000
E64.8 Sequelae of other nutritional deficiencies
0.212 0.788 0.000
E64.3 Sequelae of rickets
0.212 0.788 0.000
E64.2 Sequelae of vitamin C deficiency
0.212 0.788 0.000
E64.1 Sequelae of vitamin A deficiency
0.212 0.788 0.000
E64.0 Sequelae of protein-energy malnutrition
0.212 0.788 0.000
E53.8 Deficiency of other specified B group vitamins
0.209 0.791 0.000
E51.9 Thiamine deficiency, unspecified
0.206 0.794 0.000
E51.8 Other manifestations of thiamine deficiency
0.206 0.794 0.000
E51.1 Beriberi
0.206 0.794 0.000
E22 Hyperfunction of pituitary gland
0.201 0.798 0.000
E53.1 Pyridoxine deficiency
0.198 0.802 0.000
E53.0 Riboflavin deficiency
0.198 0.802 0.000
E51.2 Wernicke's encephalopathy
0.198 0.802 0.000
E56.9 Vitamin deficiency, unspecified
0.197 0.803 0.000
E56.8 Deficiency of other vitamins
0.197 0.803 0.000
E56.0 Deficiency of vitamin E
0.197 0.803 0.000
E34.0 Carcinoid syndrome
0.191 0.809 0.000
E34.9 Endocrine disorder, unspecified
0.190 0.810 0.000
E67.8 Other specified hyperalimentation
0.190 0.810 0.000
E67.3 Hypervitaminosis D
0.190 0.810 0.000
E67.2 Megavitamin-B6 syndrome
0.190 0.810 0.000
E67.1 Hypercarotenaemia
0.190 0.810 0.000
E67.0 Hypervitaminosis A
0.190 0.810 0.000
E55.0 Rickets, active
0.185 0.815 0.000
E26.9 Hyperaldosteronism, unspecified
0.184 0.816 0.001
E26.8 Other hyperaldosteronism
0.184 0.816 0.001
E26.1 Secondary hyperaldosteronism
0.184 0.816 0.001
E56.1 Deficiency of vitamin K
0.177 0.823 0.000
E27 Other disorders of adrenal gland
0.168 0.832 0.000
E53.9 Vitamin B deficiency, unspecified
0.165 0.835 0.000
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene
0.000 0.837 0.163
E61.9 Deficiency of nutrient element, unspecified
0.153 0.847 0.000
E61.8 Deficiency of other specified nutrient elements
0.153 0.847 0.000
E61.7 Deficiency of multiple nutrient elements
0.153 0.847 0.000
E61.6 Vanadium deficiency
0.153 0.847 0.000
E61.5 Molybdenum deficiency
0.153 0.847 0.000
E61.4 Chromium deficiency
0.153 0.847 0.000
E61.3 Manganese deficiency
0.153 0.847 0.000
E61.0 Copper deficiency
0.153 0.847 0.000
E29.1 Testicular hypofunction
0.150 0.850 0.000
E55.9 Vitamin D deficiency, unspecified
0.147 0.853 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.145 0.855 0.000
E22.8 Other hyperfunction of pituitary gland
0.145 0.855 0.000
E22.1 Hyperprolactinaemia
0.143 0.857 0.000
E06.3 Autoimmune thyroiditis
0.139 0.861 0.000
E61.2 Magnesium deficiency
0.137 0.862 0.000
E27.9 Disorder of adrenal gland, unspecified
0.132 0.868 0.000
E11.2 With renal complications
0.126 0.873 0.001
E27.5 Adrenomedullary hyperfunction
0.120 0.879 0.000
E27.0 Other adrenocortical overactivity
0.120 0.879 0.000
E27.1 Primary adrenocortical insufficiency
0.120 0.880 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.106 0.894 0.000
E66 Obesity
0.106 0.894 0.000
E27.2 Addisonian crisis
0.104 0.895 0.000
E22.0 Acromegaly and pituitary gigantism
0.104 0.896 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.101 0.898 0.000
E61.1 Iron deficiency
0.099 0.901 0.000
E11.4 With neurological complications
0.096 0.904 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.000 0.907 0.093
G24 Dystonia
0.000 0.909 0.091
G25 Other extrapyramidal and movement disorders
0.000 0.910 0.090
G24.9 Dystonia, unspecified
0.000 0.911 0.089
G24.3 Spasmodic torticollis
0.000 0.913 0.087
D64.9 Anaemia, unspecified
0.084 0.916 0.000
E26.0 Primary hyperaldosteronism
0.082 0.917 0.001
G20-G26 Extrapyramidal and movement disorders
0.000 0.918 0.082
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.081 0.919 0.000
G24.8 Other dystonia
0.000 0.922 0.078
E66.1 Drug-induced obesity
0.076 0.924 0.000
E66.8 Other obesity
0.076 0.924 0.000
G25.9 Extrapyramidal and movement disorder, unspecified
0.000 0.925 0.075
E66.0 Obesity due to excess calories
0.073 0.927 0.000
G25.5 Other chorea
0.000 0.928 0.072
G25.1 Drug-induced tremor
0.000 0.929 0.071
G24.5 Blepharospasm
0.000 0.930 0.070
G25.0 Essential tremor
0.000 0.932 0.068
G24.0 Drug-induced dystonia
0.000 0.933 0.067
G25.2 Other specified forms of tremor
0.000 0.933 0.067
G24.4 Idiopathic orofacial dystonia
0.000 0.934 0.066
G24.2 Idiopathic nonfamilial dystonia
0.000 0.934 0.066
G24.1 Idiopathic familial dystonia
0.000 0.934 0.066
E04 Other non-toxic goitre
0.065 0.935 0.000
G25.6 Drug-induced tics and other tics of organic origin
0.000 0.935 0.065
G25.4 Drug-induced chorea
0.000 0.935 0.065
E83 Disorders of mineral metabolism
0.016 0.935 0.049
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.000 0.941 0.059
G22 Parkinsonism in diseases classified elsewhere
0.000 0.941 0.059
G25.3 Myoclonus
0.000 0.941 0.059
E66.2 Extreme obesity with alveolar hypoventilation
0.058 0.941 0.000
G21 Secondary Parkinsonism
0.000 0.943 0.057
G23 Other degenerative diseases of basal ganglia
0.000 0.945 0.055
D64 Other anaemias
0.051 0.949 0.000
E04.8 Other specified non-toxic goitre
0.047 0.953 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.011 0.953 0.035
E83.8 Other disorders of mineral metabolism
0.011 0.953 0.035
E83.2 Disorders of zinc metabolism
0.011 0.953 0.035
E83.0 Disorders of copper metabolism
0.011 0.953 0.035
K90-K93 Other diseases of the digestive system
0.046 0.953 0.000
G21.9 Secondary Parkinsonism, unspecified
0.000 0.959 0.041
G21.8 Other secondary Parkinsonism
0.000 0.959 0.041
G21.3 Postencephalitic Parkinsonism
0.000 0.959 0.041
G21.2 Secondary Parkinsonism due to other external agents
0.000 0.959 0.041
G21.1 Other drug-induced secondary Parkinsonism
0.000 0.959 0.041
G21.0 Malignant neuroleptic syndrome
0.000 0.959 0.041
E27.8 Other specified disorders of adrenal gland
0.039 0.959 0.002
G21.4 Vascular parkinsonism
0.000 0.960 0.039
G23.9 Degenerative disease of basal ganglia, unspecified
0.000 0.960 0.039
G23.3 Multiple system atrophy, cerebellar type
0.000 0.960 0.039
G23.2 Striatonigral degeneration
0.000 0.960 0.039
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]
0.000 0.960 0.039
G23.0 Hallervorden-Spatz disease
0.000 0.960 0.039
D64.3 Other sideroblastic anaemias
0.037 0.963 0.000
E83.3 Disorders of phosphorus metabolism
0.008 0.963 0.030
D64.4 Congenital dyserythropoietic anaemia
0.036 0.963 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.036 0.963 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.036 0.963 0.000
D64.0 Hereditary sideroblastic anaemia
0.036 0.963 0.000
G23.8 Other specified degenerative diseases of basal ganglia
0.000 0.965 0.035
E04.0 Non-toxic diffuse goitre
0.034 0.966 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.033 0.966 0.000
D60-D64 Aplastic and other anaemias
0.032 0.968 0.000
K40-K46 Hernia
0.000 0.968 0.032
D64.8 Other specified anaemias
0.031 0.969 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.029 0.971 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.029 0.971 0.000
K41 Femoral hernia
0.000 0.972 0.028
E04.9 Non-toxic goitre, unspecified
0.028 0.972 0.000
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene
0.000 0.975 0.025
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.024 0.976 0.000
K93.1 Megacolon in Chagas' disease
0.024 0.976 0.000
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.024 0.976 0.000
J06.9 Acute upper respiratory infection, unspecified
0.000 0.976 0.024
K44 Diaphragmatic hernia
0.000 0.977 0.023
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.022 0.977 0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene
0.000 0.977 0.023
D62 Acute posthaemorrhagic anaemia
0.022 0.978 0.000
D63.1 Anaemia in other chronic diseases classified elsewhere
0.021 0.979 0.000
K41.1 Bilateral femoral hernia, with gangrene
0.000 0.980 0.020
K41.0 Bilateral femoral hernia, with obstruction, without gangrene
0.000 0.980 0.020
E83.4 Disorders of magnesium metabolism
0.011 0.980 0.009
K44.0 Diaphragmatic hernia with obstruction, without gangrene
0.000 0.980 0.020
K41.4 Unilateral or unspecified femoral hernia, with gangrene
0.000 0.980 0.020
K44.1 Diaphragmatic hernia with gangrene
0.000 0.980 0.020
D61 Other aplastic anaemias
0.020 0.980 0.000
E70-E90 Metabolic disorders
0.019 0.981 0.001
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.019 0.981 0.000
K41.2 Bilateral femoral hernia, without obstruction or gangrene
0.000 0.981 0.018
D51 Vitamin B12 deficiency anaemia
0.018 0.982 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.018 0.982 0.000
D60.8 Other acquired pure red cell aplasias
0.016 0.984 0.000
D60.1 Transient acquired pure red cell aplasia
0.016 0.984 0.000
D60.0 Chronic acquired pure red cell aplasia
0.016 0.984 0.000
E83.5 Disorders of calcium metabolism
0.015 0.984 0.001
D60.9 Acquired pure red cell aplasia, unspecified
0.015 0.984 0.000
E73 Lactose intolerance
0.015 0.985 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.014 0.985 0.001
K46 Unspecified abdominal hernia
0.000 0.985 0.014
K45 Other abdominal hernia
0.000 0.986 0.014
D61.8 Other specified aplastic anaemias
0.014 0.986 0.000
D61.3 Idiopathic aplastic anaemia
0.014 0.986 0.000
D61.2 Aplastic anaemia due to other external agents
0.014 0.986 0.000
E84 Cystic fibrosis
0.014 0.986 0.001
D50-D53 Nutritional anaemias
0.014 0.986 0.000
E77 Disorders of glycoprotein metabolism
0.014 0.986 0.001
E76 Disorders of glycosaminoglycan metabolism
0.014 0.986 0.001
E72 Other disorders of amino-acid metabolism
0.014 0.986 0.001
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.014 0.986 0.001
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.014 0.986 0.001
E74 Other disorders of carbohydrate metabolism
0.014 0.986 0.001
E70 Disorders of aromatic amino-acid metabolism
0.013 0.986 0.001
D51.8 Other vitamin B12 deficiency anaemias
0.014 0.986 0.000
E85 Amyloidosis
0.013 0.986 0.001
D51.2 Transcobalamin II deficiency
0.013 0.987 0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.013 0.987 0.000
D61.0 Constitutional aplastic anaemia
0.013 0.987 0.000
E79 Disorders of purine and pyrimidine metabolism
0.013 0.987 0.001
D61.1 Drug-induced aplastic anaemia
0.013 0.987 0.000
D61.9 Aplastic anaemia, unspecified
0.013 0.987 0.000
D51.3 Other dietary vitamin B12 deficiency anaemia
0.013 0.987 0.000
E73.9 Lactose intolerance, unspecified
0.012 0.987 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.012 0.988 0.000
E85.4 Organ-limited amyloidosis
0.012 0.988 0.000
N87.9 Dysplasia of cervix uteri, unspecified
0.000 0.988 0.012
D53 Other nutritional anaemias
0.012 0.988 0.000
E75.5 Other lipid storage disorders
0.011 0.988 0.000
E73.8 Other lactose intolerance
0.011 0.989 0.000
E73.1 Secondary lactase deficiency
0.011 0.989 0.000
E73.0 Congenital lactase deficiency
0.011 0.989 0.000
E04.2 Non-toxic multinodular goitre
0.011 0.989 0.000
E75.6 Lipid storage disorder, unspecified
0.010 0.989 0.001
E75.4 Neuronal ceroid lipofuscinosis
0.010 0.989 0.001
E75.3 Sphingolipidosis, unspecified
0.010 0.989 0.001
E75.2 Other sphingolipidosis
0.010 0.989 0.001
E75.1 Other gangliosidosis
0.010 0.989 0.001
E75.0 GM2 gangliosidosis
0.010 0.989 0.001
K46.1 Unspecified abdominal hernia with gangrene
0.000 0.989 0.011
E84.0 Cystic fibrosis with pulmonary manifestations
0.010 0.989 0.001
K45.1 Other specified abdominal hernia with gangrene
0.000 0.989 0.010
E84.8 Cystic fibrosis with other manifestations
0.010 0.989 0.001
E84.1 Cystic fibrosis with intestinal manifestations
0.010 0.989 0.001
E84.9 Cystic fibrosis, unspecified
0.010 0.990 0.000
D50 Iron deficiency anaemia
0.010 0.990 0.000
E71.3 Disorders of fatty-acid metabolism
0.010 0.990 0.001
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.010 0.990 0.001
E71.1 Other disorders of branched-chain amino-acid metabolism
0.010 0.990 0.001
E71.0 Maple-syrup-urine disease
0.010 0.990 0.001
E72.9 Disorder of amino-acid metabolism, unspecified
0.010 0.990 0.001
E72.8 Other specified disorders of amino-acid metabolism
0.010 0.990 0.001
E72.5 Disorders of glycine metabolism
0.010 0.990 0.001
E72.4 Disorders of ornithine metabolism
0.010 0.990 0.001
E72.3 Disorders of lysine and hydroxylysine metabolism
0.010 0.990 0.001
E72.2 Disorders of urea cycle metabolism
0.010 0.990 0.001
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.010 0.990 0.001
E72.0 Disorders of amino-acid transport
0.010 0.990 0.001
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.010 0.990 0.001
E76.8 Other disorders of glucosaminoglycan metabolism
0.010 0.990 0.001
E76.3 Mucopolysaccharidosis, unspecified
0.010 0.990 0.001
E76.2 Other mucopolysaccharidoses
0.010 0.990 0.001
E76.1 Mucopolysaccharidosis, type II
0.010 0.990 0.001
E76.0 Mucopolysaccharidosis, type I
0.010 0.990 0.001
E77.9 Disorder of glycoprotein metabolism, unspecified
0.010 0.990 0.001
E77.8 Other disorders of glycoprotein metabolism
0.010 0.990 0.001
E77.1 Defects in glycoprotein degradation
0.010 0.990 0.001
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.010 0.990 0.001
E74.9 Disorder of carbohydrate metabolism, unspecified
0.010 0.990 0.001
E74.8 Other specified disorders of carbohydrate metabolism
0.010 0.990 0.001
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.010 0.990 0.001
E74.2 Disorders of galactose metabolism
0.010 0.990 0.001
E74.1 Disorders of fructose metabolism
0.010 0.990 0.001
E74.0 Glycogen storage disease
0.010 0.990 0.001
J06 Acute upper respiratory infections of multiple and unspecified sites
0.000 0.990 0.010
R27.0 Ataxia, unspecified
0.000 0.990 0.010
E74.3 Other disorders of intestinal carbohydrate absorption
0.010 0.990 0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.010 0.990 0.001
E70.8 Other disorders of aromatic amino-acid metabolism
0.010 0.990 0.001
E70.2 Disorders of tyrosine metabolism
0.010 0.990 0.001
E70.1 Other hyperphenylalaninaemias
0.010 0.990 0.001
E70.0 Classical phenylketonuria
0.010 0.990 0.001
E85.8 Other amyloidosis
0.010 0.990 0.001
E85.2 Heredofamilial amyloidosis, unspecified
0.010 0.990 0.001
E85.1 Neuropathic heredofamilial amyloidosis
0.010 0.990 0.001
E85.0 Nonneuropathic heredofamilial amyloidosis
0.010 0.990 0.001
E70.3 Albinism
0.009 0.990 0.001
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.009 0.990 0.001
E79.8 Other disorders of purine and pyrimidine metabolism
0.009 0.990 0.001
E79.1 Lesch-Nyhan syndrome
0.009 0.990 0.001
D53.9 Nutritional anaemia, unspecified
0.009 0.990 0.000
E85.3 Secondary systemic amyloidosis
0.009 0.991 0.001
D50.8 Other iron deficiency anaemias
0.009 0.991 0.000
K46.0 Unspecified abdominal hernia with obstruction, without gangrene
0.000 0.991 0.009
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.008 0.991 0.001
E11.9 Without complications
0.009 0.991 0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.009 0.991 0.000
D53.8 Other specified nutritional anaemias
0.008 0.991 0.000
D53.2 Scorbutic anaemia
0.008 0.991 0.000
D53.0 Protein deficiency anaemia
0.008 0.991 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.008 0.991 0.001
J35.8 Other chronic diseases of tonsils and adenoids
0.000 0.991 0.009
K42 Umbilical hernia
0.000 0.991 0.009
K45.0 Other specified abdominal hernia with obstruction, without gangrene
0.000 0.992 0.008
R27.8 Other and unspecified lack of coordination
0.000 0.992 0.008
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.008 0.992 0.000
N40 Hyperplasia of prostate
0.000 0.992 0.008
R27 Other lack of coordination
0.000 0.992 0.008
N87 Dysplasia of cervix uteri
0.000 0.992 0.008
D50.1 Sideropenic dysphagia
0.008 0.992 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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