TreeWAS – Variant ID: rs6926737

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.000	1.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.000	1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.000	1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.000	1.000
E05.0 Thyrotoxicosis with diffuse goitre	1.000	0.000	0.000
K90.0 Coeliac disease	1.000	0.000	0.000
L40.9 Psoriasis, unspecified	0.000	0.000	1.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.000	1.000
M06.9 Rheumatoid arthritis, unspecified	0.000	0.000	1.000
G35 Multiple sclerosis	1.000	0.000	0.000
M06 Other rheumatoid arthritis	0.000	0.000	1.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.000	1.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.000	1.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	1.000	0.000	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	1.000	0.000	0.000
D86 Sarcoidosis	1.000	0.000	0.000
D80-D89 Certain disorders involving the immune mechanism	1.000	0.000	0.000
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
M05 Seropositive rheumatoid arthritis	0.000	0.000	1.000
M05-M14 Inflammatory polyarthropathies	0.000	0.000	1.000
M06.3 Rheumatoid nodule	0.000	0.000	1.000
D69 Purpura and other haemorrhagic conditions	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.999	0.001	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.000	0.001	0.999
D86.0 Sarcoidosis of lung	0.998	0.002	0.000
D69.6 Thrombocytopenia, unspecified	0.998	0.002	0.000
L40 Psoriasis	0.000	0.003	0.997
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.003	0.997
R31 Unspecified haematuria	0.000	0.004	0.996
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.005	0.995
M06.0 Seronegative rheumatoid arthritis	0.000	0.005	0.995
L40.5 Arthropathic psoriasis	0.000	0.006	0.994
D86.9 Sarcoidosis, unspecified	0.994	0.006	0.000
M06.34 Rheumatoid nodule (Hand)	0.000	0.007	0.993
D50-D53 Nutritional anaemias	0.991	0.009	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.012	0.988
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.000	0.018	0.982
K90 Intestinal malabsorption	0.976	0.024	0.000
D52 Folate deficiency anaemia	0.968	0.032	0.000
D68 Other coagulation defects	0.965	0.035	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.038	0.962
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.041	0.959
D51 Vitamin B12 deficiency anaemia	0.954	0.046	0.000
D52.9 Folate deficiency anaemia, unspecified	0.952	0.048	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.053	0.947
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.058	0.942
D69.3 Idiopathic thrombocytopenic purpura	0.942	0.058	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.000	0.060	0.940
M07 Psoriatic and enteropathic arthropathies	0.000	0.069	0.931
C82.0 Small cleaved cell, follicular	0.000	0.074	0.926
K90.9 Intestinal malabsorption, unspecified	0.926	0.074	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.916	0.084	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.000	0.087	0.913
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.093	0.907
M06.37 Rheumatoid nodule (Ankle and foot)	0.000	0.094	0.906
D68.5 Primary Thrombophilia	0.905	0.095	0.000
D69.4 Other primary thrombocytopenia	0.904	0.096	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.904	0.096	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.902	0.098	0.000
L40.0 Psoriasis vulgaris	0.000	0.101	0.899
M14 Arthropathies in other diseases classified elsewhere	0.000	0.105	0.895
E27.1 Primary adrenocortical insufficiency	0.894	0.106	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.108	0.892
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.111	0.889
M07.3 Other psoriatic arthropathies	0.000	0.114	0.886
M06.4 Inflammatory polyarthropathy	0.000	0.121	0.879
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.852	0.148	0.000
K90.8 Other intestinal malabsorption	0.850	0.150	0.000
C82.3 Follicular lymphoma grade IIIa	0.000	0.154	0.846
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.156	0.844
M07.39 Other psoriatic arthropathies (Site unspecified)	0.000	0.157	0.843
M14.6 Neuropathic arthropathy	0.000	0.162	0.838
M06.30 Rheumatoid nodule (Multiple sites)	0.000	0.166	0.834
D68.8 Other specified coagulation defects	0.832	0.168	0.000
D86.3 Sarcoidosis of skin	0.830	0.170	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.829	0.171	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.000	0.190	0.810
D69.8 Other specified haemorrhagic conditions	0.801	0.199	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.000	0.201	0.799
D86.1 Sarcoidosis of lymph nodes	0.793	0.207	0.000
M12 Other specific arthropathies	0.000	0.213	0.787
D89.9 Disorder involving the immune mechanism, unspecified	0.786	0.214	0.000
E27 Other disorders of adrenal gland	0.777	0.223	0.000
D55-D59 Haemolytic anaemias	0.776	0.224	0.000
M05.8 Other seropositive rheumatoid arthritis	0.000	0.229	0.771
D60-D64 Aplastic and other anaemias	0.770	0.230	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.233	0.767
D89.0 Polyclonal hypergammaglobulinaemia	0.766	0.234	0.000
L40.4 Guttate psoriasis	0.000	0.235	0.765
D69.0 Allergic purpura	0.764	0.236	0.000
C82.2 Large cell, follicular	0.000	0.236	0.764
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.752	0.248	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.252	0.748
M06.04 Seronegative rheumatoid arthritis (Hand)	0.000	0.256	0.744
M06.8 Other specified rheumatoid arthritis	0.000	0.265	0.735
D68.1 Hereditary factor XI deficiency	0.728	0.272	0.000
L40.8 Other psoriasis	0.000	0.273	0.727
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.000	0.275	0.725
D69.5 Secondary thrombocytopenia	0.724	0.276	0.000
D68.9 Coagulation defect, unspecified	0.723	0.277	0.000
D68.6 Other Thrombophilia	0.721	0.279	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.283	0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.283	0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.283	0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.283	0.717
M06.2 Rheumatoid bursitis	0.000	0.283	0.717
D81 Combined immunodeficiencies	0.717	0.283	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.000	0.283	0.717
M05.1 Rheumatoid lung disease	0.000	0.283	0.717
M05.0 Felty's syndrome	0.000	0.283	0.717
M09 Juvenile arthritis in diseases classified elsewhere	0.000	0.283	0.717
M08 Juvenile arthritis	0.000	0.283	0.717
M06.39 Rheumatoid nodule (Site unspecified)	0.000	0.283	0.717
M06.38 Rheumatoid nodule (Other)	0.000	0.283	0.717
M06.36 Rheumatoid nodule (Lower leg)	0.000	0.283	0.717
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.000	0.283	0.717
M06.33 Rheumatoid nodule (Forearm)	0.000	0.283	0.717
M06.31 Rheumatoid nodule (Shoulder region)	0.000	0.283	0.717
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.717	0.283	0.000
D61 Other aplastic anaemias	0.715	0.285	0.000
L40.2 Acrodermatitis continua	0.000	0.285	0.715
D51.8 Other vitamin B12 deficiency anaemias	0.714	0.286	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.000	0.287	0.713
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.000	0.287	0.713
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.000	0.287	0.713
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.000	0.287	0.713
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.000	0.287	0.713
D83 Common variable immunodeficiency	0.706	0.294	0.000
C82.6 Cutaneous follicle centre lymphoma	0.000	0.296	0.704
C82.5 Diffuse follicle centre lymphoma	0.000	0.296	0.704
D82 Immunodeficiency associated with other major defects	0.701	0.299	0.000
K90.3 Pancreatic steatorrhoea	0.700	0.300	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.700	0.300	0.000
K90.1 Tropical sprue	0.700	0.300	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.000	0.305	0.695
C82.4 Follicular lymphoma grade IIIb	0.000	0.305	0.695
D52.8 Other folate deficiency anaemias	0.694	0.306	0.000
D52.1 Drug-induced folate deficiency anaemia	0.694	0.306	0.000
D52.0 Dietary folate deficiency anaemia	0.694	0.306	0.000
E27.2 Addisonian crisis	0.692	0.308	0.000
L40.1 Generalised pustular psoriasis	0.000	0.308	0.692
D86.8 Sarcoidosis of other and combined sites	0.692	0.308	0.000
D51.2 Transcobalamin II deficiency	0.684	0.316	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.684	0.316	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.000	0.320	0.680
D89.1 Cryoglobulinaemia	0.679	0.320	0.000
D68.4 Acquired coagulation factor deficiency	0.671	0.329	0.000
D68.2 Hereditary deficiency of other clotting factors	0.668	0.332	0.000
M07.5 Arthropathy in ulcerative colitis	0.000	0.332	0.668
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.000	0.332	0.668
M07.2 Psoriatic spondylitis	0.000	0.332	0.668
M07.1 Arthritis mutilans	0.000	0.332	0.668
M07.0 Distal interphalangeal psoriatic arthropathy	0.000	0.332	0.668
D61.9 Aplastic anaemia, unspecified	0.666	0.334	0.000
D67 Hereditary factor IX deficiency	0.666	0.334	0.000
M06.1 Adult-onset Still's disease	0.000	0.335	0.665
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.000	0.335	0.665
D66 Hereditary factor VIII deficiency	0.664	0.336	0.000
M14.2 Diabetic arthropathy	0.000	0.338	0.662
D69.1 Qualitative platelet defects	0.661	0.338	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.000	0.342	0.658
M05.2 Rheumatoid vasculitis	0.000	0.343	0.657
M07.30 Other psoriatic arthropathies (Multiple sites)	0.000	0.348	0.652
M07.6 Other enteropathic arthropathies	0.000	0.352	0.648
D59 Acquired haemolytic anaemia	0.648	0.352	0.000
D89.3 Immune reconstitution syndrome	0.647	0.353	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.645	0.355	0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.000	0.359	0.641
M14.4 Arthropathy in amyloidosis	0.000	0.359	0.641
M14.3 Lipoid dermatoarthritis	0.000	0.359	0.641
M14.1 Crystal arthropathy in other metabolic disorders	0.000	0.359	0.641
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.000	0.359	0.641
E20-E35 Disorders of other endocrine glands	0.637	0.363	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.635	0.364	0.000
M07.38 Other psoriatic arthropathies (Other)	0.000	0.365	0.635
M07.33 Other psoriatic arthropathies (Forearm)	0.000	0.365	0.635
M07.32 Other psoriatic arthropathies (Upper arm)	0.000	0.365	0.635
D53 Other nutritional anaemias	0.632	0.368	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.000	0.369	0.631
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.000	0.369	0.631
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.000	0.369	0.631
M06.44 Inflammatory polyarthropathy (Hand)	0.000	0.369	0.631
M06.43 Inflammatory polyarthropathy (Forearm)	0.000	0.369	0.631
M06.42 Inflammatory polyarthropathy (Upper arm)	0.000	0.369	0.631
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.000	0.369	0.631
J32.9 Chronic sinusitis, unspecified	0.000	0.370	0.630
D84 Other immunodeficiencies	0.630	0.370	0.000
M12.3 Palindromic rheumatism	0.000	0.378	0.622
M07.31 Other psoriatic arthropathies (Shoulder region)	0.000	0.388	0.612
E00-E07 Disorders of thyroid gland	0.611	0.389	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.608	0.392	0.000
D61.0 Constitutional aplastic anaemia	0.607	0.393	0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.000	0.393	0.607
D51.3 Other dietary vitamin B12 deficiency anaemia	0.604	0.396	0.000
M12.2 Villonodular synovitis (pigmented)	0.000	0.408	0.592
D68.0 Von Willebrand's disease	0.582	0.418	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.582	0.418	0.000
L40.3 Pustulosis palmaris et plantaris	0.000	0.418	0.582
E27.9 Disorder of adrenal gland, unspecified	0.581	0.419	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.000	0.419	0.581
D69.2 Other nonthrombocytopenic purpura	0.578	0.421	0.000
D57 Sickle-cell disorders	0.575	0.425	0.000
D56 Thalassaemia	0.574	0.426	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.573	0.427	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.000	0.428	0.572
E28 Ovarian dysfunction	0.568	0.432	0.000
M12.5 Traumatic arthropathy	0.000	0.434	0.566
E27.3 Drug-induced adrenocortical insufficiency	0.565	0.435	0.000
M12.4 Intermittent hydrarthrosis	0.000	0.436	0.564
M12.1 Kaschin-Beck disease	0.000	0.436	0.564
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.000	0.436	0.564
D69.9 Haemorrhagic condition, unspecified	0.561	0.439	0.000
D80 Immunodeficiency with predominantly antibody defects	0.558	0.441	0.000
E27.5 Adrenomedullary hyperfunction	0.557	0.443	0.000
E27.0 Other adrenocortical overactivity	0.557	0.443	0.000
D55 Anaemia due to enzyme disorders	0.556	0.444	0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.000	0.447	0.553
M05.88 Other seropositive rheumatoid arthritis (Other)	0.000	0.447	0.553
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.000	0.447	0.553
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.000	0.447	0.553
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.000	0.447	0.553
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.000	0.447	0.553
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.000	0.447	0.553
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.000	0.447	0.553
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.000	0.447	0.553
E05.8 Other thyrotoxicosis	0.550	0.449	0.000
M12.8 Other specific arthropathies, not elsewhere classified	0.000	0.452	0.548
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.000	0.455	0.545
E22 Hyperfunction of pituitary gland	0.544	0.456	0.000
D50 Iron deficiency anaemia	0.544	0.456	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.539	0.461	0.000
D59.1 Other autoimmune haemolytic anaemias	0.538	0.462	0.000
G37 Other demyelinating diseases of central nervous system	0.536	0.464	0.000
M11 Other crystal arthropathies	0.000	0.464	0.536
M14.8 Arthropathies in other specified diseases classified elsewhere	0.000	0.469	0.531
M13 Other arthritis	0.000	0.472	0.528
M06.88 Other specified rheumatoid arthritis (Other)	0.000	0.473	0.527
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.000	0.473	0.527
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.000	0.473	0.527
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.000	0.473	0.527
M06.84 Other specified rheumatoid arthritis (Hand)	0.000	0.473	0.527
M06.83 Other specified rheumatoid arthritis (Forearm)	0.000	0.473	0.527
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.000	0.473	0.527
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.000	0.473	0.527
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.000	0.473	0.526
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.523	0.477	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.477	0.523
D64 Other anaemias	0.522	0.478	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.521	0.479	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.000	0.486	0.514
M06.28 Rheumatoid bursitis (Other)	0.000	0.486	0.514
M06.27 Rheumatoid bursitis (Ankle and foot)	0.000	0.486	0.514
M06.26 Rheumatoid bursitis (Lower leg)	0.000	0.486	0.514
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.000	0.486	0.514
M06.24 Rheumatoid bursitis (Hand)	0.000	0.486	0.514
M06.23 Rheumatoid bursitis (Forearm)	0.000	0.486	0.514
M06.22 Rheumatoid bursitis (Upper arm)	0.000	0.486	0.514
M06.21 Rheumatoid bursitis (Shoulder region)	0.000	0.486	0.514
M06.20 Rheumatoid bursitis (Multiple sites)	0.000	0.486	0.514
D81.9 Combined immunodeficiency, unspecified	0.514	0.486	0.000
D81.8 Other combined immunodeficiencies	0.514	0.486	0.000
D81.7 Major histocompatibility complex class II deficiency	0.514	0.486	0.000
D81.6 Major histocompatibility complex class I deficiency	0.514	0.486	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.514	0.486	0.000
D81.4 Nezelof's syndrome	0.514	0.486	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.514	0.486	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.514	0.486	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.514	0.486	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.514	0.486	0.000
M05.09 Felty's syndrome (Site unspecified)	0.000	0.486	0.514
M05.08 Felty's syndrome (Other)	0.000	0.486	0.514
M05.07 Felty's syndrome (Ankle and foot)	0.000	0.486	0.514
M05.06 Felty's syndrome (Lower leg)	0.000	0.486	0.514
M05.05 Felty's syndrome (Pelvic region and thigh)	0.000	0.486	0.514
M05.04 Felty's syndrome (Hand)	0.000	0.486	0.514
M05.03 Felty's syndrome (Forearm)	0.000	0.486	0.514
M05.02 Felty's syndrome (Upper arm)	0.000	0.486	0.514
M05.01 Felty's syndrome (Shoulder region)	0.000	0.486	0.514
M05.00 Felty's syndrome (Multiple sites)	0.000	0.486	0.514
M05.19 Rheumatoid lung disease (Site unspecified)	0.000	0.486	0.514
M05.18 Rheumatoid lung disease (Other)	0.000	0.486	0.514
M05.17 Rheumatoid lung disease (Ankle and foot)	0.000	0.486	0.514
M05.16 Rheumatoid lung disease (Lower leg)	0.000	0.486	0.514
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.000	0.486	0.514
M05.14 Rheumatoid lung disease (Hand)	0.000	0.486	0.514
M05.13 Rheumatoid lung disease (Forearm)	0.000	0.486	0.514
M05.12 Rheumatoid lung disease (Upper arm)	0.000	0.486	0.514
M05.11 Rheumatoid lung disease (Shoulder region)	0.000	0.486	0.514
M05.10 Rheumatoid lung disease (Multiple sites)	0.000	0.486	0.514
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.000	0.486	0.514
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.000	0.486	0.514
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.000	0.486	0.514
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.000	0.486	0.514
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.000	0.486	0.514
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.000	0.486	0.514
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.000	0.486	0.514
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.000	0.486	0.514
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.000	0.486	0.514
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.000	0.486	0.514
M08.9 Juvenile arthritis, unspecified	0.000	0.486	0.514
M08.8 Other juvenile arthritis	0.000	0.486	0.514
M08.4 Pauciarticular juvenile arthritis	0.000	0.486	0.514
M08.3 Juvenile polyarthritis (seronegative)	0.000	0.486	0.514
M08.2 Juvenile arthritis with systemic onset	0.000	0.486	0.514
M08.1 Juvenile ankylosing spondylitis	0.000	0.486	0.514
M08.0 Juvenile rheumatoid arthritis	0.000	0.486	0.514
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.000	0.486	0.514
M09.2 Juvenile arthritis in ulcerative colitis	0.000	0.486	0.514
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.000	0.486	0.514
M09.0 Juvenile arthritis in psoriasis	0.000	0.486	0.514
D61.8 Other specified aplastic anaemias	0.513	0.487	0.000
D61.3 Idiopathic aplastic anaemia	0.513	0.487	0.000
D61.2 Aplastic anaemia due to other external agents	0.513	0.487	0.000
D83.8 Other common variable immunodeficiencies	0.506	0.493	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.506	0.493	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.506	0.493	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.506	0.493	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.503	0.497	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.503	0.497	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.503	0.497	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.503	0.497	0.000
D82.2 Immunodeficiency with short-limbed stature	0.503	0.497	0.000
D82.0 Wiskott-Aldrich syndrome	0.503	0.497	0.000
E31 Polyglandular dysfunction	0.500	0.500	0.000
D83.9 Common variable immunodeficiency, unspecified	0.496	0.504	0.000
M12.24 Villonodular synovitis (pigmented) (Hand)	0.000	0.505	0.495
D59.9 Acquired haemolytic anaemia, unspecified	0.492	0.508	0.000
M12.30 Palindromic rheumatism (Multiple sites)	0.000	0.509	0.491
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.487	0.513	0.000
D82.1 Di George's syndrome	0.487	0.513	0.000
E28.3 Primary ovarian failure	0.487	0.513	0.000
D73 Diseases of spleen	0.486	0.514	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.485	0.515	0.000
D64.8 Other specified anaemias	0.480	0.520	0.000
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)	0.000	0.521	0.479
M07.08 Distal interphalangeal proriatic arthropathy-Other	0.000	0.521	0.479
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)	0.000	0.521	0.479
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg	0.000	0.521	0.479
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh	0.000	0.521	0.479
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)	0.000	0.521	0.479
M07.03 Distal interphalangeal proriatic arthropathy-Forearm	0.000	0.521	0.479
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm	0.000	0.521	0.479
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region	0.000	0.521	0.479
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)	0.000	0.521	0.479
M07.19 Arthritis mutilans (Site unspecified)	0.000	0.521	0.479
M07.18 Arthritis mutilans (Other)	0.000	0.521	0.479
M07.17 Arthritis mutilans (Ankle and foot)	0.000	0.521	0.479
M07.16 Arthritis mutilans (Lower leg)	0.000	0.521	0.479
M07.15 Arthritis mutilans (Pelvic region and thigh)	0.000	0.521	0.479
M07.14 Arthritis mutilans (Hand)	0.000	0.521	0.479
M07.13 Arthritis mutilans (Forearm)	0.000	0.521	0.479
M07.12 Arthritis mutilans (Upper arm)	0.000	0.521	0.479
M07.11 Arthritis mutilans (Shoulder region)	0.000	0.521	0.479
M07.10 Arthritis mutilans (Multiple sites)	0.000	0.521	0.479
M07.29 Psoriatic spondylitis (Site unspecified)	0.000	0.521	0.479
M07.28 Psoriatic spondylitis (Other)	0.000	0.521	0.479
M07.27 Psoriatic spondylitis (Ankle and foot)	0.000	0.521	0.479
M07.26 Psoriatic spondylitis (Lower leg)	0.000	0.521	0.479
M07.25 Psoriatic spondylitis (Pelvic region and thigh)	0.000	0.521	0.479
M07.24 Psoriatic spondylitis (Hand)	0.000	0.521	0.479
M07.23 Psoriatic spondylitis (Forearm)	0.000	0.521	0.479
M07.22 Psoriatic spondylitis (Upper arm)	0.000	0.521	0.479
M07.21 Psoriatic spondylitis (Shoulder region)	0.000	0.521	0.479
M07.20 Psoriatic spondylitis (Multiple sites)	0.000	0.521	0.479
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)	0.000	0.521	0.479
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)	0.000	0.521	0.479
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)	0.000	0.521	0.479
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)	0.000	0.521	0.479
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)	0.000	0.521	0.479
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)	0.000	0.521	0.479
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)	0.000	0.521	0.479
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)	0.000	0.521	0.479
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)	0.000	0.521	0.479
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)	0.000	0.521	0.479
M07.59 Arthropathy in ulcerative colitis (Site unspecified)	0.000	0.521	0.479
M07.58 Arthropathy in ulcerative colitis (Other)	0.000	0.521	0.479
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)	0.000	0.521	0.479
M07.56 Arthropathy in ulcerative colitis (Lower leg)	0.000	0.521	0.479
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)	0.000	0.521	0.479
M07.54 Arthropathy in ulcerative colitis (Hand)	0.000	0.521	0.479
M07.53 Arthropathy in ulcerative colitis (Forearm)	0.000	0.521	0.479
M07.52 Arthropathy in ulcerative colitis (Upper arm)	0.000	0.521	0.479
M07.51 Arthropathy in ulcerative colitis (Shoulder region)	0.000	0.521	0.479
M07.50 Arthropathy in ulcerative colitis (Multiple sites)	0.000	0.521	0.479
E34 Other endocrine disorders	0.478	0.522	0.000
M06.19 Adult-onset Still's disease (Site unspecified)	0.000	0.523	0.477
M06.18 Adult-onset Still's disease (Other)	0.000	0.523	0.477
M06.17 Adult-onset Still's disease (Ankle and foot)	0.000	0.523	0.477
M06.16 Adult-onset Still's disease (Lower leg)	0.000	0.523	0.477
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.000	0.523	0.477
M06.14 Adult-onset Still's disease (Hand)	0.000	0.523	0.477
M06.13 Adult-onset Still's disease (Forearm)	0.000	0.523	0.477
M06.12 Adult-onset Still's disease (Upper arm)	0.000	0.523	0.477
M06.11 Adult-onset Still's disease (Shoulder region)	0.000	0.523	0.477
D84.1 Defects in the complement system	0.473	0.526	0.000
M05.28 Rheumatoid vasculitis (Other)	0.000	0.529	0.471
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.000	0.529	0.471
M05.26 Rheumatoid vasculitis (Lower leg)	0.000	0.529	0.471
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.000	0.529	0.471
M05.24 Rheumatoid vasculitis (Hand)	0.000	0.529	0.471
M05.23 Rheumatoid vasculitis (Forearm)	0.000	0.529	0.471
M05.22 Rheumatoid vasculitis (Upper arm)	0.000	0.529	0.471
M05.21 Rheumatoid vasculitis (Shoulder region)	0.000	0.529	0.471
M05.20 Rheumatoid vasculitis (Multiple sites)	0.000	0.529	0.471
E20 Hypoparathyroidism	0.471	0.529	0.000
E28.2 Polycystic ovarian syndrome	0.470	0.530	0.000
E24 Cushing's syndrome	0.468	0.532	0.000
L40-L45 Papulosquamous disorders	0.007	0.532	0.461
D59.0 Drug-induced autoimmune haemolytic anaemia	0.467	0.533	0.000
M07.68 Other enteropathic arthropathies (Other)	0.000	0.535	0.465
M07.67 Other enteropathic arthropathies (Ankle and foot)	0.000	0.535	0.465
M07.66 Other enteropathic arthropathies (Lower leg)	0.000	0.535	0.465
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)	0.000	0.535	0.465
M07.64 Other enteropathic arthropathies (Hand)	0.000	0.535	0.465
M07.63 Other enteropathic arthropathies (Forearm)	0.000	0.535	0.465
M07.62 Other enteropathic arthropathies (Upper arm)	0.000	0.535	0.465
M07.61 Other enteropathic arthropathies (Shoulder region)	0.000	0.535	0.465
M07.60 Other enteropathic arthropathies (Multiple sites)	0.000	0.535	0.465
D59.8 Other acquired haemolytic anaemias	0.464	0.535	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.464	0.535	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.464	0.535	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.464	0.535	0.000
D59.3 Haemolytic-uraemic syndrome	0.464	0.535	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.464	0.535	0.000
M12.39 Palindromic rheumatism (Site unspecified)	0.000	0.537	0.463
E10 Insulin-dependent diabetes mellitus	0.000	0.543	0.457
E35 Disorders of endocrine glands in diseases classified elsewhere	0.457	0.543	0.000
E32 Diseases of thymus	0.457	0.543	0.000
E30 Disorders of puberty, not elsewhere classified	0.457	0.543	0.000
D73.5 Infarction of spleen	0.454	0.546	0.000
D53.8 Other specified nutritional anaemias	0.453	0.547	0.000
D53.2 Scorbutic anaemia	0.453	0.547	0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.453	0.547	0.000
D53.0 Protein deficiency anaemia	0.453	0.547	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.452	0.548	0.000
D62 Acute posthaemorrhagic anaemia	0.452	0.548	0.000
D76.3 Other histiocytosis syndromes	0.450	0.549	0.000
D58 Other hereditary haemolytic anaemias	0.449	0.551	0.000
M12.38 Palindromic rheumatism (Other)	0.000	0.554	0.446
M12.37 Palindromic rheumatism (Ankle and foot)	0.000	0.554	0.446
M12.36 Palindromic rheumatism (Lower leg)	0.000	0.554	0.446
M12.35 Palindromic rheumatism (Pelvic region and thigh)	0.000	0.554	0.446
M12.34 Palindromic rheumatism (Hand)	0.000	0.554	0.446
M12.33 Palindromic rheumatism (Forearm)	0.000	0.554	0.446
M12.32 Palindromic rheumatism (Upper arm)	0.000	0.554	0.446
M12.31 Palindromic rheumatism (Shoulder region)	0.000	0.554	0.446
M07.69 Other enteropathic arthropathies (Site unspecified)	0.000	0.554	0.445
D56.9 Thalassaemia, unspecified	0.445	0.554	0.000
E07 Other disorders of thyroid	0.445	0.555	0.000
E10.9 Without complications	0.000	0.560	0.440
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.438	0.562	0.000
E00 Congenital iodine-deficiency syndrome	0.438	0.562	0.000
D84.8 Other specified immunodeficiencies	0.437	0.563	0.000
M45 Ankylosing spondylitis	0.000	0.563	0.437
E22.9 Hyperfunction of pituitary gland, unspecified	0.436	0.564	0.000
E10.3 With ophthalmic complications	0.000	0.568	0.432
D57.1 Sickle-cell anaemia without crisis	0.431	0.569	0.000
E27.8 Other specified disorders of adrenal gland	0.430	0.569	0.000
E22.0 Acromegaly and pituitary gigantism	0.428	0.572	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.427	0.573	0.000
E50-E64 Other nutritional deficiencies	0.426	0.574	0.000
M13.1 Monoarthritis, not elsewhere classified	0.000	0.575	0.425
M06.10 Adult-onset Still's disease (Multiple sites)	0.000	0.575	0.425
M12.29 Villonodular synovitis (pigmented) (Site unspecified)	0.000	0.575	0.425
M12.28 Villonodular synovitis (pigmented) (Other)	0.000	0.575	0.425
M12.27 Villonodular synovitis (pigmented) (Ankle and foot)	0.000	0.575	0.425
M12.25 Villonodular synovitis (pigmented) (Pelvic region and thigh)	0.000	0.575	0.425
M12.23 Villonodular synovitis (pigmented) (Forearm)	0.000	0.575	0.425
M12.22 Villonodular synovitis (pigmented) (Upper arm)	0.000	0.575	0.425
M12.21 Villonodular synovitis (pigmented) (Shoulder region)	0.000	0.575	0.425
M12.20 Villonodular synovitis (pigmented) (Multiple sites)	0.000	0.575	0.425
D63 Anaemia in chronic diseases classified elsewhere	0.423	0.576	0.000
D50.1 Sideropenic dysphagia	0.422	0.578	0.000
E10.5 With peripheral circulatory complications	0.000	0.578	0.422
D80.1 Nonfamilial hypogammaglobulinaemia	0.421	0.578	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.000	0.580	0.420
D50.9 Iron deficiency anaemia, unspecified	0.420	0.580	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.420	0.580	0.000
D56.1 Beta thalassaemia	0.417	0.583	0.000
D61.1 Drug-induced aplastic anaemia	0.413	0.586	0.000
M13.8 Other specified arthritis	0.000	0.587	0.413
D57.8 Other sickle-cell disorders	0.412	0.588	0.000
D57.3 Sickle-cell trait	0.412	0.588	0.000
D57.2 Double heterozygous sickling disorders	0.412	0.588	0.000
D57.0 Sickle-cell anaemia with crisis	0.412	0.588	0.000
M05.29 Rheumatoid vasculitis (Site unspecified)	0.000	0.588	0.411
D56.8 Other thalassaemias	0.412	0.588	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.412	0.588	0.000
D56.2 Delta-beta thalassaemia	0.412	0.588	0.000
D56.0 Alpha thalassaemia	0.412	0.588	0.000
J33.9 Nasal polyp, unspecified	0.000	0.591	0.409
M12.57 Traumatic arthropathy (Ankle and foot)	0.000	0.592	0.408
E10.6 With other specified complications	0.000	0.593	0.407
E28.9 Ovarian dysfunction, unspecified	0.407	0.593	0.000
E28.8 Other ovarian dysfunction	0.407	0.593	0.000
E28.1 Androgen excess	0.407	0.593	0.000
E28.0 Oestrogen excess	0.407	0.593	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations