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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs6928398
log Bayes Factor = 77.5153
Chromosome 6   position 32,838,269  (GRCh37) Explore rs6928398 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.999 0.001 0.000
E10-E14 Diabetes mellitus
0.997 0.003 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.996 0.004 0.000
E20-E35 Disorders of other endocrine glands
0.969 0.031 0.000
E10.1 With ketoacidosis
0.941 0.059 0.000
E24 Cushing's syndrome
0.937 0.063 0.000
E23 Hypofunction and other disorders of pituitary gland
0.918 0.082 0.000
E10.3 With ophthalmic complications
0.891 0.109 0.000
E83.1 Disorders of iron metabolism
0.000 0.112 0.888
E23.2 Diabetes insipidus
0.886 0.114 0.000
E10.8 With unspecified complications
0.877 0.123 0.000
E10.0 With coma
0.862 0.138 0.000
E03.8 Other specified hypothyroidism
0.845 0.155 0.000
E24.9 Cushing's syndrome, unspecified
0.829 0.171 0.000
E24.0 Pituitary-dependent Cushing's disease
0.829 0.171 0.000
E28 Ovarian dysfunction
0.825 0.175 0.000
E10.2 With renal complications
0.825 0.175 0.000
E29 Testicular dysfunction
0.817 0.183 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.798 0.202 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.787 0.213 0.000
K90 Intestinal malabsorption
0.784 0.216 0.000
E13 Other specified diabetes mellitus
0.772 0.228 0.000
E24.2 Drug-induced Cushing's syndrome
0.757 0.242 0.000
E28.3 Primary ovarian failure
0.753 0.247 0.000
E23.7 Disorder of pituitary gland, unspecified
0.743 0.257 0.000
E24.8 Other Cushing's syndrome
0.729 0.271 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.720 0.280 0.000
E10.4 With neurological complications
0.719 0.281 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.714 0.285 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.713 0.287 0.000
E29.1 Testicular hypofunction
0.708 0.292 0.000
E10.7 With multiple complications
0.707 0.293 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.707 0.293 0.000
E10.5 With peripheral circulatory complications
0.702 0.298 0.000
E07 Other disorders of thyroid
0.701 0.299 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.695 0.305 0.000
E32 Diseases of thymus
0.695 0.305 0.000
E31 Polyglandular dysfunction
0.695 0.305 0.000
E30 Disorders of puberty, not elsewhere classified
0.695 0.305 0.000
E25 Adrenogenital disorders
0.695 0.305 0.000
E23.6 Other disorders of pituitary gland
0.681 0.319 0.000
E26 Hyperaldosteronism
0.680 0.320 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.672 0.328 0.000
E24.3 Ectopic ACTH syndrome
0.672 0.328 0.000
E24.1 Nelson's syndrome
0.672 0.328 0.000
E10.6 With other specified complications
0.671 0.329 0.000
E20 Hypoparathyroidism
0.667 0.333 0.000
E03.1 Congenital hypothyroidism without goitre
0.663 0.337 0.000
E40-E46 Malnutrition
0.659 0.341 0.000
E23.1 Drug-induced hypopituitarism
0.658 0.342 0.000
K90.9 Intestinal malabsorption, unspecified
0.655 0.345 0.000
E14 Unspecified diabetes mellitus
0.644 0.356 0.000
E06 Thyroiditis
0.640 0.360 0.000
E13.9 Without complications
0.640 0.360 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.636 0.364 0.000
E05.8 Other thyrotoxicosis
0.634 0.365 0.000
E07.8 Other specified disorders of thyroid
0.620 0.380 0.000
E28.9 Ovarian dysfunction, unspecified
0.592 0.408 0.000
E28.8 Other ovarian dysfunction
0.592 0.408 0.000
E28.1 Androgen excess
0.592 0.408 0.000
E28.0 Oestrogen excess
0.592 0.408 0.000
E29.9 Testicular dysfunction, unspecified
0.586 0.414 0.000
E29.8 Other testicular dysfunction
0.586 0.414 0.000
E29.0 Testicular hyperfunction
0.586 0.414 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.580 0.420 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.573 0.427 0.000
K90.3 Pancreatic steatorrhoea
0.562 0.438 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.562 0.438 0.000
K90.1 Tropical sprue
0.562 0.438 0.000
E34 Other endocrine disorders
0.557 0.443 0.000
E14.3 With ophthalmic complications
0.555 0.445 0.000
K90.8 Other intestinal malabsorption
0.555 0.445 0.000
E13.8 With unspecified complications
0.554 0.446 0.000
E13.7 With multiple complications
0.554 0.446 0.000
E13.6 With other specified complications
0.554 0.446 0.000
E13.5 With peripheral circulatory complications
0.554 0.446 0.000
E13.4 With neurological complications
0.554 0.446 0.000
E13.2 With renal complications
0.554 0.446 0.000
E13.1 With ketoacidosis
0.554 0.446 0.000
E13.0 With coma
0.554 0.446 0.000
E14.1 With ketoacidosis
0.516 0.483 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.514 0.486 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.514 0.486 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.514 0.486 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.514 0.486 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.514 0.486 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.514 0.486 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.514 0.486 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.514 0.486 0.000
E12.9 Without complications
0.512 0.488 0.000
E12.8 With unspecified complications
0.512 0.488 0.000
E12.7 With multiple complications
0.512 0.488 0.000
E12.6 With other specified complications
0.512 0.488 0.000
E12.5 With peripheral circulatory complications
0.512 0.488 0.000
E12.4 With neurological complications
0.512 0.488 0.000
E12.3 With ophthalmic complications
0.512 0.488 0.000
E12.2 With renal complications
0.512 0.488 0.000
E12.1 With ketoacidosis
0.512 0.488 0.000
E12.0 With coma
0.512 0.488 0.000
E15 Nondiabetic hypoglycaemic coma
0.511 0.489 0.000
E16 Other disorders of pancreatic internal secretion
0.509 0.491 0.000
E13.3 With ophthalmic complications
0.507 0.493 0.000
E07.1 Dyshormogenetic goitre
0.503 0.497 0.000
E07.0 Hypersecretion of calcitonin
0.503 0.497 0.000
E14.5 With peripheral circulatory complications
0.501 0.499 0.000
E25.9 Adrenogenital disorder, unspecified
0.498 0.501 0.000
E25.8 Other adrenogenital disorders
0.498 0.501 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.498 0.501 0.000
E30.9 Disorder of puberty, unspecified
0.498 0.501 0.000
E30.8 Other disorders of puberty
0.498 0.501 0.000
E30.1 Precocious puberty
0.498 0.501 0.000
E30.0 Delayed puberty
0.498 0.501 0.000
E31.9 Polyglandular dysfunction, unspecified
0.498 0.501 0.000
E31.8 Other polyglandular dysfunction
0.498 0.501 0.000
E31.1 Polyglandular hyperfunction
0.498 0.501 0.000
E31.0 Autoimmune polyglandular failure
0.498 0.501 0.000
E32.9 Disease of thymus, unspecified
0.498 0.501 0.000
E32.8 Other diseases of thymus
0.498 0.501 0.000
E32.1 Abscess of thymus
0.498 0.501 0.000
E32.0 Persistent hyperplasia of thymus
0.498 0.501 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.498 0.501 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.498 0.501 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.498 0.501 0.000
E06.5 Other chronic thyroiditis
0.497 0.502 0.000
E28.2 Polycystic ovarian syndrome
0.494 0.506 0.000
E04 Other non-toxic goitre
0.489 0.511 0.000
E14.4 With neurological complications
0.488 0.512 0.000
E26.9 Hyperaldosteronism, unspecified
0.487 0.512 0.000
E26.8 Other hyperaldosteronism
0.487 0.512 0.000
E26.1 Secondary hyperaldosteronism
0.487 0.512 0.000
E20.8 Other hypoparathyroidism
0.478 0.521 0.000
E20.1 Pseudohypoparathyroidism
0.478 0.521 0.000
E20.0 Idiopathic hypoparathyroidism
0.478 0.521 0.000
E21.2 Other hyperparathyroidism
0.473 0.526 0.000
E26.0 Primary hyperaldosteronism
0.472 0.528 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.472 0.528 0.000
E45 Retarded development following protein-energy malnutrition
0.472 0.528 0.000
E43 Unspecified severe protein-energy malnutrition
0.472 0.528 0.000
E42 Marasmic kwashiorkor
0.472 0.528 0.000
E41 Nutritional marasmus
0.472 0.528 0.000
E40 Kwashiorkor
0.472 0.528 0.000
E14.8 With unspecified complications
0.470 0.530 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.468 0.532 0.000
E06.9 Thyroiditis, unspecified
0.464 0.536 0.000
E14.7 With multiple complications
0.462 0.538 0.000
E14.0 With coma
0.462 0.538 0.000
E06.4 Drug-induced thyroiditis
0.459 0.541 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.459 0.541 0.000
E06.0 Acute thyroiditis
0.459 0.541 0.000
E21.4 Other specified disorders of parathyroid gland
0.456 0.544 0.000
E20.9 Hypoparathyroidism, unspecified
0.450 0.549 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.446 0.554 0.000
E06.1 Subacute thyroiditis
0.444 0.555 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.438 0.562 0.000
E21.0 Primary hyperparathyroidism
0.429 0.571 0.000
E04.0 Non-toxic diffuse goitre
0.426 0.574 0.000
E34.8 Other specified endocrine disorders
0.421 0.579 0.000
E34.3 Short stature, not elsewhere classified
0.418 0.581 0.000
E46 Unspecified protein-energy malnutrition
0.417 0.583 0.000
E21.3 Hyperparathyroidism, unspecified
0.404 0.596 0.000
E34.5 Androgen resistance syndrome
0.399 0.600 0.000
E34.4 Constitutional tall stature
0.399 0.600 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.399 0.600 0.000
E34.1 Other hypersecretion of intestinal hormones
0.399 0.600 0.000
E22 Hyperfunction of pituitary gland
0.398 0.602 0.000
E14.2 Withrenal complications
0.397 0.603 0.000
E14.6 With other specified complications
0.379 0.621 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.365 0.635 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.365 0.635 0.000
E16.4 Abnormal secretion of gastrin
0.365 0.635 0.000
E16.3 Increased secretion of glucagon
0.365 0.635 0.000
E04.8 Other specified non-toxic goitre
0.351 0.649 0.000
E16.1 Other hypoglycaemia
0.342 0.658 0.000
E44.1 Mild protein-energy malnutrition
0.339 0.661 0.000
E44.0 Moderate protein-energy malnutrition
0.339 0.661 0.000
E34.0 Carcinoid syndrome
0.336 0.664 0.000
E06.3 Autoimmune thyroiditis
0.328 0.672 0.000
E65-E68 Obesity and other hyperalimentation
0.318 0.682 0.000
E27 Other disorders of adrenal gland
0.305 0.694 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.294 0.706 0.000
E22.8 Other hyperfunction of pituitary gland
0.285 0.714 0.000
E34.9 Endocrine disorder, unspecified
0.279 0.720 0.000
E04.2 Non-toxic multinodular goitre
0.277 0.723 0.000
E23.0 Hypopituitarism
0.276 0.724 0.000
E22.1 Hyperprolactinaemia
0.263 0.737 0.000
E22.0 Acromegaly and pituitary gigantism
0.259 0.741 0.000
E04.1 Non-toxic single thyroid nodule
0.255 0.745 0.000
E16.2 Hypoglycaemia, unspecified
0.255 0.745 0.000
E27.1 Primary adrenocortical insufficiency
0.253 0.747 0.000
E50-E64 Other nutritional deficiencies
0.247 0.752 0.001
E27.8 Other specified disorders of adrenal gland
0.233 0.767 0.000
E67 Other hyperalimentation
0.228 0.772 0.000
E68 Sequelae of hyperalimentation
0.228 0.772 0.000
E27.5 Adrenomedullary hyperfunction
0.219 0.781 0.000
E27.0 Other adrenocortical overactivity
0.219 0.781 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.205 0.795 0.000
E04.9 Non-toxic goitre, unspecified
0.180 0.820 0.000
E54 Ascorbic acid deficiency
0.179 0.821 0.001
E07.9 Disorder of thyroid, unspecified
0.178 0.821 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.177 0.822 0.001
E63 Other nutritional deficiencies
0.177 0.822 0.001
E56 Other vitamin deficiencies
0.177 0.822 0.001
E50 Vitamin A deficiency
0.177 0.822 0.001
E60 Dietary zinc deficiency
0.177 0.822 0.001
E59 Dietary selenium deficiency
0.177 0.822 0.001
E52 Niacin deficiency [pellagra]
0.177 0.822 0.001
E51 Thiamine deficiency
0.176 0.824 0.001
E67.8 Other specified hyperalimentation
0.163 0.836 0.000
E67.3 Hypervitaminosis D
0.163 0.836 0.000
E67.2 Megavitamin-B6 syndrome
0.163 0.836 0.000
E67.1 Hypercarotenaemia
0.163 0.836 0.000
E67.0 Hypervitaminosis A
0.163 0.836 0.000
E53 Deficiency of other B group vitamins
0.142 0.858 0.000
E65 Localised adiposity
0.140 0.860 0.001
E58 Dietary calcium deficiency
0.137 0.862 0.001
E27.2 Addisonian crisis
0.133 0.866 0.001
E61 Deficiency of other nutrient elements
0.132 0.867 0.001
E50.9 Vitamin A deficiency, unspecified
0.127 0.872 0.001
E50.8 Other manifestations of vitamin A deficiency
0.127 0.872 0.001
E50.7 Other ocular manifestations of vitamin A deficiency
0.127 0.872 0.001
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.127 0.872 0.001
E50.5 Vitamin A deficiency with night blindness
0.127 0.872 0.001
E50.4 Vitamin A deficiency with keratomalacia
0.127 0.872 0.001
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.127 0.872 0.001
E50.2 Vitamin A deficiency with corneal xerosis
0.127 0.872 0.001
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.127 0.872 0.001
E50.0 Vitamin A deficiency with conjunctival xerosis
0.127 0.872 0.001
E56.9 Vitamin deficiency, unspecified
0.127 0.872 0.001
E56.8 Deficiency of other vitamins
0.127 0.872 0.001
E56.1 Deficiency of vitamin K
0.127 0.872 0.001
E56.0 Deficiency of vitamin E
0.127 0.872 0.001
E63.9 Nutritional deficiency, unspecified
0.127 0.872 0.001
E63.8 Other specified nutritional deficiencies
0.127 0.872 0.001
E63.1 Imbalance of constituents of food intake
0.127 0.872 0.001
E63.0 Essential fatty acid [EFA] deficiency
0.127 0.872 0.001
E64.9 Sequelae of unspecified nutritional deficiency
0.127 0.872 0.001
E64.8 Sequelae of other nutritional deficiencies
0.127 0.872 0.001
E64.3 Sequelae of rickets
0.127 0.872 0.001
E64.2 Sequelae of vitamin C deficiency
0.127 0.872 0.001
E64.1 Sequelae of vitamin A deficiency
0.127 0.872 0.001
E64.0 Sequelae of protein-energy malnutrition
0.127 0.872 0.001
T36-T50 Poisoning by drugs, medicaments and biological substances
0.000 0.873 0.127
E27.4 Other and unspecified adrenocortical insufficiency
0.127 0.873 0.000
E51.9 Thiamine deficiency, unspecified
0.126 0.873 0.001
E51.8 Other manifestations of thiamine deficiency
0.126 0.873 0.001
E51.1 Beriberi
0.126 0.873 0.001
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.000 0.874 0.126
E51.2 Wernicke's encephalopathy
0.125 0.875 0.001
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.000 0.875 0.125
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.000 0.881 0.119
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.000 0.881 0.119
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.000 0.881 0.119
T43.2 Other and unspecified antidepressants
0.000 0.881 0.119
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.000 0.883 0.117
T46 Poisoning by agents primarily affecting the cardiovascular system
0.000 0.886 0.114
T50.9 Other and unspecified drugs, medicaments and biological substances
0.000 0.886 0.114
E53.9 Vitamin B deficiency, unspecified
0.112 0.888 0.000
E27.9 Disorder of adrenal gland, unspecified
0.110 0.889 0.001
E55 Vitamin D deficiency
0.109 0.890 0.001
T39.0 Salicylates
0.000 0.891 0.109
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.000 0.895 0.105
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.000 0.896 0.104
E11 Non-insulin-dependent diabetes mellitus
0.104 0.896 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.000 0.896 0.104
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.000 0.897 0.103
E53.1 Pyridoxine deficiency
0.102 0.898 0.000
E53.0 Riboflavin deficiency
0.102 0.898 0.000
T42.1 Iminostilbenes
0.000 0.898 0.102
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.100 0.899 0.001
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.000 0.900 0.100
T46.4 Angiotensin-converting-enzyme inhibitors
0.000 0.902 0.098
E61.9 Deficiency of nutrient element, unspecified
0.095 0.905 0.001
E61.8 Deficiency of other specified nutrient elements
0.095 0.905 0.001
E61.7 Deficiency of multiple nutrient elements
0.095 0.905 0.001
E61.6 Vanadium deficiency
0.095 0.905 0.001
E61.5 Molybdenum deficiency
0.095 0.905 0.001
E61.4 Chromium deficiency
0.095 0.905 0.001
E61.3 Manganese deficiency
0.095 0.905 0.001
E61.0 Copper deficiency
0.095 0.905 0.001
T42.0 Hydantoin derivatives
0.000 0.905 0.095
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.000 0.906 0.094
E61.2 Magnesium deficiency
0.094 0.906 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.000 0.907 0.093
T46.1 Calcium-channel blockers
0.000 0.907 0.093
T47.1 Other antacids and anti-gastric-secretion drugs
0.000 0.907 0.093
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.000 0.907 0.093
E83 Disorders of mineral metabolism
0.006 0.908 0.087
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.000 0.908 0.092
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.000 0.908 0.092
T41 Poisoning by anaesthetics and therapeutic gases
0.000 0.908 0.092
T50.4 Drugs affecting uric acid metabolism
0.000 0.908 0.091
E11.1 With ketoacidosis
0.091 0.909 0.000
T42.4 Benzodiazepines
0.000 0.909 0.090
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.000 0.910 0.090
T42.5 Mixed antiepileptics, not elsewhere classified
0.000 0.910 0.090
T42.3 Barbiturates
0.000 0.910 0.090
T42.2 Succinimides and oxazolidinediones
0.000 0.910 0.090
T39.4 Antirheumatics, not elsewhere classified
0.000 0.910 0.090
T39.2 Pyrazolone derivatives
0.000 0.910 0.090
E11.2 With renal complications
0.089 0.911 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.000 0.914 0.086
T43.6 Psychostimulants with abuse potential
0.000 0.915 0.085
T50.8 Diagnostic agents
0.000 0.915 0.085
T50.7 Analeptics and opioid receptor antagonists
0.000 0.915 0.085
T50.5 Appetite depressants
0.000 0.915 0.085
T50.3 Electrolytic, caloric and water-balance agents
0.000 0.915 0.085
T50.1 Loop [high-ceiling] diuretics
0.000 0.915 0.085
T50.0 Mineralocorticoids and their antagonists
0.000 0.915 0.085
T43.9 Psychotropic drug, unspecified
0.000 0.916 0.084
T43.8 Other psychotropic drugs, not elsewhere classified
0.000 0.916 0.084
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.000 0.918 0.082
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.000 0.918 0.082
T46.8 Antivaricose drugs, including sclerosing agents
0.000 0.918 0.082
T46.7 Peripheral vasodilators
0.000 0.918 0.082
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.000 0.918 0.082
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.000 0.918 0.082
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.000 0.918 0.081
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.000 0.919 0.081
T46.3 Coronary vasodilators, not elsewhere classified
0.000 0.919 0.081
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.000 0.920 0.080
E11.7 With multiple complications
0.080 0.920 0.000
E55.0 Rickets, active
0.078 0.921 0.001
T50.6 Antidotes and chelating agents, not elsewhere classified
0.000 0.922 0.078
T38.1 Thyroid hormones and substitutes
0.000 0.922 0.077
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.000 0.924 0.076
T47.8 Other agents primarily affecting the gastro-intestinal system
0.000 0.924 0.076
T47.7 Emetics
0.000 0.924 0.076
T47.5 Digestants
0.000 0.924 0.076
T47.3 Saline and osmotic laxatives
0.000 0.924 0.076
T47.0 Histamine H(2)-receptor antagonists
0.000 0.924 0.076
T46.5 Other antihypertensive drugs, not elsewhere classified
0.000 0.925 0.075
T47.2 Stimulant laxatives
0.000 0.925 0.075
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.000 0.925 0.075
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.000 0.925 0.075
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.000 0.925 0.075
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.000 0.925 0.075
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.000 0.925 0.075
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.000 0.925 0.075
T44.1 Other parasympathomimetics [cholinergics]
0.000 0.925 0.075
T44.0 Anticholinesterase agents
0.000 0.925 0.075
T47.4 Other laxatives
0.000 0.927 0.073
E66 Obesity
0.071 0.929 0.000
T47.6 Antidiarrhoeal drugs
0.000 0.929 0.071
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.000 0.930 0.070
T39.1 4-Aminophenol derivatives
0.000 0.930 0.070
E11.8 With unspecified complications
0.068 0.932 0.000
T37.8 Other specified systemic anti-infectives and antiparasitics
0.000 0.932 0.068
T38.9 Other and unspecified hormone antagonists
0.000 0.933 0.067
T38.7 Androgens and anabolic congeners
0.000 0.933 0.067
T38.5 Other oestrogens and progestogens
0.000 0.933 0.067
T38.4 Oral contraceptives
0.000 0.933 0.067
T38.2 Antithyroid drugs
0.000 0.933 0.067
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.000 0.933 0.067
T37.5 Antiviral drugs
0.000 0.933 0.067
T37.4 Anthelminthics
0.000 0.933 0.067
T37.3 Other antiprotozoal drugs
0.000 0.933 0.067
T37.2 Antimalarials and drugs acting on other blood protozoa
0.000 0.933 0.067
T37.1 Antimycobacterial drugs
0.000 0.933 0.067
T37.0 Sulphonamides
0.000 0.933 0.067
E83.9 Disorder of mineral metabolism, unspecified
0.004 0.933 0.062
E83.8 Other disorders of mineral metabolism
0.004 0.933 0.062
E83.2 Disorders of zinc metabolism
0.004 0.933 0.062
E83.0 Disorders of copper metabolism
0.004 0.933 0.062
T41.5 Therapeutic gases
0.000 0.934 0.066
T41.4 Anaesthetic, unspecified
0.000 0.934 0.066
T41.3 Local anaesthetics
0.000 0.934 0.066
T41.2 Other and unspecified general anaesthetics
0.000 0.934 0.066
T41.1 Intravenous anaesthetics
0.000 0.934 0.066
T41.0 Inhaled anaesthetics
0.000 0.934 0.066
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.000 0.934 0.066
T48.6 Antiasthmatics, not elsewhere classified
0.000 0.934 0.066
T48.5 Anti-common-cold drugs
0.000 0.934 0.066
T48.4 Expectorants
0.000 0.934 0.066
T48.3 Antitussives
0.000 0.934 0.066
T48.2 Other and unspecified agents primarily acting on muscles
0.000 0.934 0.066
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.000 0.934 0.066
T48.0 Oxytocic drugs
0.000 0.934 0.066
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.000 0.935 0.064
T36 Poisoning by systemic antibiotics
0.000 0.936 0.064
T38.8 Other and unspecified hormones and their synthetic substitutes
0.000 0.936 0.064
T38.0 Glucocorticoids and synthetic analogues
0.000 0.936 0.064
T49.9 Topical agent, unspecified
0.000 0.938 0.062
T49.8 Other topical agents
0.000 0.938 0.062
T49.7 Dental drugs, topically applied
0.000 0.938 0.062
T49.6 Otorhinolaryngological drugs and preparations
0.000 0.938 0.062
T49.5 Ophthalmological drugs and preparations
0.000 0.938 0.062
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.000 0.938 0.062
T49.3 Emollients, demulcents and protectants
0.000 0.938 0.062
T49.2 Local astringents and local detergents
0.000 0.938 0.062
T49.1 Antipruritics
0.000 0.938 0.062
T43.4 Butyrophenone and thioxanthene neuroleptics
0.000 0.940 0.060
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.000 0.942 0.058
E11.4 With neurological complications
0.057 0.943 0.000
E11.6 With other specified complications
0.056 0.944 0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.000 0.944 0.056
E66.8 Other obesity
0.056 0.944 0.000
E14.9 Without complications
0.054 0.946 0.000
E11.0 With coma
0.052 0.947 0.000
E61.1 Iron deficiency
0.052 0.947 0.000
E66.1 Drug-induced obesity
0.051 0.949 0.000
E83.4 Disorders of magnesium metabolism
0.002 0.949 0.050
T45.2 Vitamins, not elsewhere classified
0.000 0.950 0.050
T43.3 Phenothiazine antipsychotics and neuroleptics
0.000 0.951 0.049
E11.5 With peripheral circulatory complications
0.049 0.951 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.000 0.953 0.047
T45.9 Primarily systemic and haematological agent, unspecified
0.000 0.953 0.046
T45.8 Other primarily systemic and haematological agents
0.000 0.953 0.046
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.000 0.953 0.046
T45.6 Fibrinolysis-affecting drugs
0.000 0.953 0.046
T45.4 Iron and its compounds
0.000 0.953 0.046
T45.3 Enzymes, not elsewhere classified
0.000 0.953 0.046
T36.9 Systemic antibiotic, unspecified
0.000 0.954 0.046
T36.8 Other systemic antibiotics
0.000 0.954 0.046
T36.7 Antifungal antibiotics, systemically used
0.000 0.954 0.046
T36.6 Rifamycins
0.000 0.954 0.046
T36.5 Aminoglycosides
0.000 0.954 0.046
T36.2 Chloramphenicol group
0.000 0.954 0.046
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.000 0.954 0.046
K90-K93 Other diseases of the digestive system
0.046 0.954 0.000
T36.3 Macrolides
0.000 0.956 0.043
E83.3 Disorders of phosphorus metabolism
0.004 0.957 0.039
E66.2 Extreme obesity with alveolar hypoventilation
0.042 0.958 0.000
T45.5 Anticoagulants
0.000 0.958 0.042
E53.8 Deficiency of other specified B group vitamins
0.041 0.959 0.000
T36.4 Tetracyclines
0.000 0.959 0.040
T45.0 Antiallergic and antiemetic drugs
0.000 0.960 0.040
E70-E90 Metabolic disorders
0.039 0.961 0.001
T40.6 Other and unspecified narcotics
0.000 0.964 0.036
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.035 0.965 0.000
E89.0 Postprocedural hypothyroidism
0.034 0.966 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.000 0.966 0.034
T40.8 Lysergide [LSD]
0.000 0.966 0.034
T40.7 Cannabis (derivatives)
0.000 0.966 0.034
T40.1 Heroin
0.000 0.966 0.034
T40.0 Opium
0.000 0.966 0.034
T36.0 Penicillins
0.001 0.967 0.033
K93 Disorders of other digestive organs in diseases classified elsewhere
0.033 0.967 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.967 0.033
T40.5 Cocaine
0.000 0.967 0.033
T45.1 Antineoplastic and immunosuppressive drugs
0.000 0.967 0.032
T40.3 Methadone
0.000 0.968 0.032
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.031 0.969 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.000 0.969 0.031
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.000 0.969 0.031
E70 Disorders of aromatic amino-acid metabolism
0.030 0.969 0.000
E74 Other disorders of carbohydrate metabolism
0.029 0.971 0.000
T40.4 Other synthetic narcotics
0.000 0.971 0.029
E73 Lactose intolerance
0.028 0.971 0.000
E77 Disorders of glycoprotein metabolism
0.028 0.972 0.001
E76 Disorders of glycosaminoglycan metabolism
0.028 0.972 0.001
E72 Other disorders of amino-acid metabolism
0.028 0.972 0.001
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.028 0.972 0.001
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.028 0.972 0.001
E84 Cystic fibrosis
0.028 0.972 0.001
E83.5 Disorders of calcium metabolism
0.001 0.972 0.028
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.028 0.972 0.001
E66.0 Obesity due to excess calories
0.025 0.974 0.001
E85 Amyloidosis
0.025 0.974 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.025 0.975 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.025 0.975 0.000
E89.5 Postprocedural testicular hypofunction
0.025 0.975 0.000
E89.1 Postprocedural hypoinsulinaemia
0.025 0.975 0.000
E88 Other metabolic disorders
0.024 0.975 0.000
E70.3 Albinism
0.024 0.976 0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.024 0.976 0.000
K93.1 Megacolon in Chagas' disease
0.024 0.976 0.000
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.024 0.976 0.000
E79 Disorders of purine and pyrimidine metabolism
0.022 0.977 0.001
L98.8 Other specified disorders of skin and subcutaneous tissue
0.023 0.977 0.000
E74.0 Glycogen storage disease
0.022 0.978 0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.022 0.978 0.000
E70.8 Other disorders of aromatic amino-acid metabolism
0.022 0.978 0.000
E70.2 Disorders of tyrosine metabolism
0.022 0.978 0.000
E70.1 Other hyperphenylalaninaemias
0.022 0.978 0.000
E70.0 Classical phenylketonuria
0.022 0.978 0.000
E89.4 Postprocedural ovarian failure
0.021 0.978 0.000
E73.9 Lactose intolerance, unspecified
0.021 0.979 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.979 0.021
E74.9 Disorder of carbohydrate metabolism, unspecified
0.021 0.979 0.000
E74.8 Other specified disorders of carbohydrate metabolism
0.021 0.979 0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.021 0.979 0.000
E74.2 Disorders of galactose metabolism
0.021 0.979 0.000
E74.1 Disorders of fructose metabolism
0.021 0.979 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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