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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs6930777
log Bayes Factor = 71.222
Chromosome 6   position 32,351,566  (GRCh37) Explore rs6930777 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
C44.3 Skin of other and unspecified parts of face
1.000 0.000 0.000
K51.9 Ulcerative colitis, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
1.000 0.000 0.000
C44 Other malignant neoplasms of skin
1.000 0.000 0.000
K51 Ulcerative colitis
1.000 0.000 0.000
Z93.2 Ileostomy status
1.000 0.000 0.000
M06 Other rheumatoid arthritis
1.000 0.000 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
1.000 0.000 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.999 0.001 0.000
C44.7 Skin of lower limb, including hip
0.999 0.001 0.000
K50-K52 Noninfective enteritis and colitis
0.999 0.001 0.000
K50 Crohn's disease [regional enteritis]
0.999 0.001 0.000
K50.1 Crohn's disease of large intestine
0.999 0.001 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.998 0.002 0.000
C44.5 Skin of trunk
0.997 0.003 0.000
M06.0 Seronegative rheumatoid arthritis
0.995 0.005 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.995 0.005 0.000
K51.4 Pseudopolyposis of colon
0.993 0.007 0.000
C44.2 Skin of ear and external auricular canal
0.992 0.008 0.000
C44.4 Skin of scalp and neck
0.988 0.012 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.983 0.017 0.000
M05-M14 Inflammatory polyarthropathies
0.981 0.019 0.000
C44.0 Skin of lip
0.973 0.027 0.000
J45.9 Asthma, unspecified
0.000 0.032 0.968
C44.6 Skin of upper limb, including shoulder
0.965 0.035 0.000
K51.8 Other ulcerative colitis
0.963 0.037 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.957 0.042 0.001
M05 Seropositive rheumatoid arthritis
0.956 0.044 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.948 0.052 0.000
K50.9 Crohn's disease, unspecified
0.947 0.053 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.946 0.054 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.939 0.061 0.000
M07 Psoriatic and enteropathic arthropathies
0.938 0.062 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.937 0.062 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.937 0.063 0.000
K51.2 Ulcerative (chronic) proctitis
0.934 0.066 0.000
C83.3 Large cell (diffuse)
0.930 0.070 0.000
C82.0 Small cleaved cell, follicular
0.915 0.085 0.000
M07.3 Other psoriatic arthropathies
0.908 0.092 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.900 0.100 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.870 0.130 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.861 0.139 0.000
C44.1 Skin of eyelid, including canthus
0.857 0.143 0.000
D86.9 Sarcoidosis, unspecified
0.000 0.158 0.842
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.839 0.161 0.000
D86 Sarcoidosis
0.000 0.163 0.837
K51.5 Mucosal proctocolitis
0.837 0.163 0.000
K52 Other non-infective gastro-enteritis and colitis
0.833 0.167 0.000
C82.3 Follicular lymphoma grade IIIa
0.830 0.170 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.828 0.172 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.827 0.173 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.820 0.180 0.000
D86.0 Sarcoidosis of lung
0.000 0.181 0.819
K51.3 Ulcerative (chronic) rectosigmoiditis
0.817 0.183 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.816 0.184 0.000
M06.3 Rheumatoid nodule
0.809 0.191 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.808 0.192 0.000
D50-D53 Nutritional anaemias
0.001 0.207 0.793
D51 Vitamin B12 deficiency anaemia
0.000 0.208 0.792
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.213 0.787
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.783 0.217 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.783 0.217 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.781 0.219 0.000
D80-D89 Certain disorders involving the immune mechanism
0.003 0.221 0.776
D50 Iron deficiency anaemia
0.000 0.224 0.776
D50.9 Iron deficiency anaemia, unspecified
0.000 0.225 0.775
M45.X9 Ankylosing spondylitis (Site unspecified)
0.773 0.227 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.771 0.229 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.005 0.237 0.758
M07.36 Other psoriatic arthropathies (Lower leg)
0.745 0.255 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.742 0.258 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.741 0.258 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.736 0.263 0.001
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.736 0.264 0.000
K90 Intestinal malabsorption
0.006 0.265 0.729
M45 Ankylosing spondylitis
0.735 0.265 0.000
C82.2 Large cell, follicular
0.735 0.265 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.725 0.275 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.718 0.282 0.000
C44.8 Overlapping lesion of skin
0.717 0.283 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.717 0.283 0.000
M06.8 Other specified rheumatoid arthritis
0.717 0.283 0.000
M06.2 Rheumatoid bursitis
0.717 0.283 0.000
M06.1 Adult-onset Still's disease
0.717 0.283 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.713 0.286 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.713 0.286 0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.713 0.286 0.000
M06.04 Seronegative rheumatoid arthritis (Hand)
0.713 0.286 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.713 0.286 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.713 0.286 0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.713 0.286 0.000
C82.6 Cutaneous follicle centre lymphoma
0.713 0.287 0.000
C82.5 Diffuse follicle centre lymphoma
0.713 0.287 0.000
C82.4 Follicular lymphoma grade IIIb
0.713 0.287 0.000
M14 Arthropathies in other diseases classified elsewhere
0.712 0.288 0.000
K52.1 Toxic gastro-enteritis and colitis
0.708 0.292 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.294 0.706
M06.4 Inflammatory polyarthropathy
0.705 0.295 0.000
M12 Other specific arthropathies
0.703 0.297 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.703 0.297 0.000
M08 Juvenile arthritis
0.703 0.297 0.000
K52.3 Indeterminate colitis
0.701 0.299 0.000
M11 Other crystal arthropathies
0.692 0.308 0.000
C85.1 B-cell lymphoma, unspecified
0.690 0.310 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.686 0.313 0.001
C94 Other leukaemias of specified cell type
0.686 0.313 0.001
C93 Monocytic leukaemia
0.686 0.313 0.001
C86 Other specified types of T/NK-cell lymphoma
0.686 0.313 0.001
C83.1 Small cleaved cell (diffuse)
0.686 0.314 0.000
M05.8 Other seropositive rheumatoid arthritis
0.686 0.314 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.686 0.314 0.000
M05.2 Rheumatoid vasculitis
0.686 0.314 0.000
M05.1 Rheumatoid lung disease
0.686 0.314 0.000
M05.0 Felty's syndrome
0.686 0.314 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.685 0.315 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.683 0.316 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.678 0.322 0.000
C85.0 Lymphosarcoma
0.678 0.322 0.000
M45-M49 Spondylopathies
0.673 0.327 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.673 0.327 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.673 0.327 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.673 0.327 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.673 0.327 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.673 0.327 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.673 0.327 0.000
M07.6 Other enteropathic arthropathies
0.673 0.327 0.000
M07.5 Arthropathy in ulcerative colitis
0.673 0.327 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.673 0.327 0.000
M07.2 Psoriatic spondylitis
0.673 0.327 0.000
M07.1 Arthritis mutilans
0.673 0.327 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.673 0.327 0.000
C83.7 Burkitt's tumour
0.672 0.328 0.000
C83.6 Undifferentiated (diffuse)
0.672 0.328 0.000
C83.5 Lymphoblastic (diffuse)
0.672 0.328 0.000
C83.4 Immunoblastic (diffuse)
0.672 0.328 0.000
C83.2 Mixed small and large cell (diffuse)
0.672 0.328 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.664 0.336 0.000
D52 Folate deficiency anaemia
0.000 0.339 0.661
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.661 0.339 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.003 0.349 0.649
M07.38 Other psoriatic arthropathies (Other)
0.651 0.349 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.651 0.349 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.651 0.349 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.651 0.349 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.651 0.349 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.651 0.349 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.644 0.356 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.643 0.357 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.634 0.366 0.000
C88 Malignant immunoproliferative diseases
0.633 0.366 0.001
M06.34 Rheumatoid nodule (Hand)
0.630 0.369 0.000
C95 Leukaemia of unspecified cell type
0.628 0.372 0.001
C84 Peripheral and cutaneous T-cell lymphomas
0.626 0.374 0.001
K50.8 Other Crohn's disease
0.625 0.375 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.608 0.392 0.000
M65-M68 Disorders of synovium and tendon
0.606 0.394 0.000
D86.8 Sarcoidosis of other and combined sites
0.000 0.400 0.600
D86.3 Sarcoidosis of skin
0.000 0.400 0.600
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.400 0.600
D86.1 Sarcoidosis of lymph nodes
0.000 0.400 0.600
C43 Malignant melanoma of skin
0.591 0.409 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.584 0.416 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.580 0.420 0.000
M06.38 Rheumatoid nodule (Other)
0.580 0.420 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.580 0.420 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.580 0.420 0.000
M06.33 Rheumatoid nodule (Forearm)
0.580 0.420 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.580 0.420 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.580 0.420 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.580 0.420 0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.574 0.426 0.000
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.432 0.568
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.432 0.568
D51.2 Transcobalamin II deficiency
0.000 0.432 0.568
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.432 0.568
D52.9 Folate deficiency anaemia, unspecified
0.000 0.433 0.567
C43.6 Malignant melanoma of upper limb, including shoulder
0.566 0.433 0.000
C81 Hodgkin's disease
0.565 0.434 0.001
K90.9 Intestinal malabsorption, unspecified
0.003 0.434 0.563
D55-D59 Haemolytic anaemias
0.004 0.441 0.555
D83 Common variable immunodeficiency
0.002 0.442 0.556
D82 Immunodeficiency associated with other major defects
0.002 0.442 0.556
D81 Combined immunodeficiencies
0.002 0.442 0.556
D50.1 Sideropenic dysphagia
0.000 0.444 0.556
M11.9 Crystal arthropathy, unspecified
0.552 0.447 0.000
M46 Other inflammatory spondylopathies
0.551 0.449 0.000
M65 Synovitis and tenosynovitis
0.545 0.455 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.544 0.456 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.543 0.456 0.000
K90.8 Other intestinal malabsorption
0.004 0.472 0.523
K90.3 Pancreatic steatorrhoea
0.005 0.473 0.522
K90.2 Blind loop syndrome, not elsewhere classified
0.005 0.473 0.522
K90.1 Tropical sprue
0.005 0.473 0.522
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.527 0.473 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.527 0.473 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.527 0.473 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.527 0.473 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.527 0.473 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.527 0.473 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.527 0.473 0.000
D80 Immunodeficiency with predominantly antibody defects
0.002 0.477 0.521
M14.6 Neuropathic arthropathy
0.519 0.481 0.000
M49 Spondylopathies in diseases classified elsewhere
0.518 0.482 0.000
M40-M43 Deforming dorsopathies
0.518 0.482 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.517 0.483 0.000
D53 Other nutritional anaemias
0.001 0.484 0.515
J45 Asthma
0.013 0.485 0.503
M06.19 Adult-onset Still's disease (Site unspecified)
0.514 0.486 0.000
M06.18 Adult-onset Still's disease (Other)
0.514 0.486 0.000
M06.17 Adult-onset Still's disease (Ankle and foot)
0.514 0.486 0.000
M06.16 Adult-onset Still's disease (Lower leg)
0.514 0.486 0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.514 0.486 0.000
M06.14 Adult-onset Still's disease (Hand)
0.514 0.486 0.000
M06.13 Adult-onset Still's disease (Forearm)
0.514 0.486 0.000
M06.12 Adult-onset Still's disease (Upper arm)
0.514 0.486 0.000
M06.11 Adult-onset Still's disease (Shoulder region)
0.514 0.486 0.000
M06.10 Adult-onset Still's disease (Multiple sites)
0.514 0.486 0.000
M06.29 Rheumatoid bursitis (Site unspecified)
0.514 0.486 0.000
M06.28 Rheumatoid bursitis (Other)
0.514 0.486 0.000
M06.27 Rheumatoid bursitis (Ankle and foot)
0.514 0.486 0.000
M06.26 Rheumatoid bursitis (Lower leg)
0.514 0.486 0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.514 0.486 0.000
M06.24 Rheumatoid bursitis (Hand)
0.514 0.486 0.000
M06.23 Rheumatoid bursitis (Forearm)
0.514 0.486 0.000
M06.22 Rheumatoid bursitis (Upper arm)
0.514 0.486 0.000
M06.21 Rheumatoid bursitis (Shoulder region)
0.514 0.486 0.000
M06.20 Rheumatoid bursitis (Multiple sites)
0.514 0.486 0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.514 0.486 0.000
M06.88 Other specified rheumatoid arthritis (Other)
0.514 0.486 0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.514 0.486 0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.514 0.486 0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.514 0.486 0.000
M06.84 Other specified rheumatoid arthritis (Hand)
0.514 0.486 0.000
M06.83 Other specified rheumatoid arthritis (Forearm)
0.514 0.486 0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.514 0.486 0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.514 0.486 0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.514 0.486 0.000
M14.8 Arthropathies in other specified diseases classified elsewhere
0.510 0.490 0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.510 0.490 0.000
M14.4 Arthropathy in amyloidosis
0.510 0.490 0.000
M14.3 Lipoid dermatoarthritis
0.510 0.490 0.000
M14.2 Diabetic arthropathy
0.510 0.490 0.000
M14.1 Crystal arthropathy in other metabolic disorders
0.510 0.490 0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.510 0.490 0.000
M10 Gout
0.506 0.493 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.505 0.495 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.505 0.495 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.505 0.495 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.505 0.495 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.505 0.495 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.505 0.495 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.505 0.495 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.505 0.495 0.000
M08.9 Juvenile arthritis, unspecified
0.504 0.495 0.000
M08.8 Other juvenile arthritis
0.504 0.495 0.000
M08.4 Pauciarticular juvenile arthritis
0.504 0.495 0.000
M08.3 Juvenile polyarthritis (seronegative)
0.504 0.495 0.000
M08.2 Juvenile arthritis with systemic onset
0.504 0.495 0.000
M08.1 Juvenile ankylosing spondylitis
0.504 0.495 0.000
M08.0 Juvenile rheumatoid arthritis
0.504 0.495 0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.504 0.495 0.000
M09.2 Juvenile arthritis in ulcerative colitis
0.504 0.495 0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.504 0.495 0.000
M09.0 Juvenile arthritis in psoriasis
0.504 0.495 0.000
M12.8 Other specific arthropathies, not elsewhere classified
0.504 0.495 0.000
M12.5 Traumatic arthropathy
0.504 0.495 0.000
M12.4 Intermittent hydrarthrosis
0.504 0.495 0.000
M12.3 Palindromic rheumatism
0.504 0.495 0.000
M12.2 Villonodular synovitis (pigmented)
0.504 0.495 0.000
M12.1 Kaschin-Beck disease
0.504 0.495 0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.504 0.495 0.000
E10.9 Without complications
0.000 0.497 0.503
M66 Spontaneous rupture of synovium and tendon
0.499 0.501 0.000
M11.8 Other specified crystal arthropathies
0.496 0.503 0.000
M11.1 Familial chondrocalcinosis
0.496 0.503 0.000
M11.0 Hydroxyapatite deposition disease
0.496 0.503 0.000
M13 Other arthritis
0.495 0.505 0.000
K52.0 Gastro-enteritis and colitis due to radiation
0.493 0.507 0.000
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.492 0.507 0.001
C86.5 Angioimmunoblastic T-cell lymphoma
0.492 0.507 0.001
C86.4 Blastic NK-cell lymphoma
0.492 0.507 0.001
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.492 0.507 0.001
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.492 0.507 0.001
C86.1 Hepatosplenic T-cell lymphoma
0.492 0.507 0.001
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.492 0.507 0.001
C93.9 Monocytic leukaemia, unspecified
0.492 0.507 0.001
C93.7 Other monocytic leukaemia
0.492 0.507 0.001
C93.3 Juvenile myelomonocytic leukaemia
0.492 0.507 0.001
C93.2 Subacute monocytic leukaemia
0.492 0.507 0.001
C93.1 Chronic monocytic leukaemia
0.492 0.507 0.001
C93.0 Acute monocytic leukaemia
0.492 0.507 0.001
C94.7 Other specified leukaemias
0.492 0.507 0.001
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.492 0.507 0.001
C94.5 Acute myelofibrosis
0.492 0.507 0.001
C94.4 Acute panmyelosis
0.492 0.507 0.001
C94.3 Mast cell leukaemia
0.492 0.507 0.001
C94.2 Acute megakaryoblastic leukaemia
0.492 0.507 0.001
C94.1 Chronic erythraemia
0.492 0.507 0.001
C94.0 Acute erythraemia and erythroleukaemia
0.492 0.507 0.001
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.492 0.507 0.001
C96.8 Histiocytic sarcoma
0.492 0.507 0.001
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.492 0.507 0.001
C96.6 Unifocal Langerhans-cell histiocytosis
0.492 0.507 0.001
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.492 0.507 0.001
C96.4 Sarcoma of dendritic cells (accessory cells)
0.492 0.507 0.001
C96.3 True histiocytic lymphoma
0.492 0.507 0.001
C96.2 Malignant mast cell tumour
0.492 0.507 0.001
C96.1 Malignant histiocytosis
0.492 0.507 0.001
C96.0 Letterer-Siwe disease
0.492 0.507 0.001
M05.09 Felty's syndrome (Site unspecified)
0.492 0.508 0.000
M05.08 Felty's syndrome (Other)
0.492 0.508 0.000
M05.07 Felty's syndrome (Ankle and foot)
0.492 0.508 0.000
M05.06 Felty's syndrome (Lower leg)
0.492 0.508 0.000
M05.05 Felty's syndrome (Pelvic region and thigh)
0.492 0.508 0.000
M05.04 Felty's syndrome (Hand)
0.492 0.508 0.000
M05.03 Felty's syndrome (Forearm)
0.492 0.508 0.000
M05.02 Felty's syndrome (Upper arm)
0.492 0.508 0.000
M05.01 Felty's syndrome (Shoulder region)
0.492 0.508 0.000
M05.00 Felty's syndrome (Multiple sites)
0.492 0.508 0.000
M05.19 Rheumatoid lung disease (Site unspecified)
0.492 0.508 0.000
M05.18 Rheumatoid lung disease (Other)
0.492 0.508 0.000
M05.17 Rheumatoid lung disease (Ankle and foot)
0.492 0.508 0.000
M05.16 Rheumatoid lung disease (Lower leg)
0.492 0.508 0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.492 0.508 0.000
M05.14 Rheumatoid lung disease (Hand)
0.492 0.508 0.000
M05.13 Rheumatoid lung disease (Forearm)
0.492 0.508 0.000
M05.12 Rheumatoid lung disease (Upper arm)
0.492 0.508 0.000
M05.11 Rheumatoid lung disease (Shoulder region)
0.492 0.508 0.000
M05.10 Rheumatoid lung disease (Multiple sites)
0.492 0.508 0.000
M05.29 Rheumatoid vasculitis (Site unspecified)
0.492 0.508 0.000
M05.28 Rheumatoid vasculitis (Other)
0.492 0.508 0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.492 0.508 0.000
M05.26 Rheumatoid vasculitis (Lower leg)
0.492 0.508 0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.492 0.508 0.000
M05.24 Rheumatoid vasculitis (Hand)
0.492 0.508 0.000
M05.23 Rheumatoid vasculitis (Forearm)
0.492 0.508 0.000
M05.22 Rheumatoid vasculitis (Upper arm)
0.492 0.508 0.000
M05.21 Rheumatoid vasculitis (Shoulder region)
0.492 0.508 0.000
M05.20 Rheumatoid vasculitis (Multiple sites)
0.492 0.508 0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.492 0.508 0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.492 0.508 0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.492 0.508 0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.492 0.508 0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.492 0.508 0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.492 0.508 0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.492 0.508 0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.492 0.508 0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.492 0.508 0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.492 0.508 0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.492 0.508 0.000
M05.88 Other seropositive rheumatoid arthritis (Other)
0.492 0.508 0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.492 0.508 0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.492 0.508 0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.492 0.508 0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.492 0.508 0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.492 0.508 0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.492 0.508 0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.492 0.508 0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.492 0.508 0.000
C43.4 Malignant melanoma of scalp and neck
0.486 0.514 0.000
C91 Lymphoid leukaemia
0.483 0.514 0.003
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.482 0.517 0.000
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.482 0.517 0.000
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.482 0.517 0.000
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.482 0.517 0.000
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.482 0.517 0.000
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.482 0.517 0.000
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.482 0.517 0.000
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.482 0.517 0.000
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.482 0.517 0.000
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.482 0.517 0.000
M07.19 Arthritis mutilans (Site unspecified)
0.482 0.517 0.000
M07.18 Arthritis mutilans (Other)
0.482 0.517 0.000
M07.17 Arthritis mutilans (Ankle and foot)
0.482 0.517 0.000
M07.16 Arthritis mutilans (Lower leg)
0.482 0.517 0.000
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.482 0.517 0.000
M07.14 Arthritis mutilans (Hand)
0.482 0.517 0.000
M07.13 Arthritis mutilans (Forearm)
0.482 0.517 0.000
M07.12 Arthritis mutilans (Upper arm)
0.482 0.517 0.000
M07.11 Arthritis mutilans (Shoulder region)
0.482 0.517 0.000
M07.10 Arthritis mutilans (Multiple sites)
0.482 0.517 0.000
M07.29 Psoriatic spondylitis (Site unspecified)
0.482 0.517 0.000
M07.28 Psoriatic spondylitis (Other)
0.482 0.517 0.000
M07.27 Psoriatic spondylitis (Ankle and foot)
0.482 0.517 0.000
M07.26 Psoriatic spondylitis (Lower leg)
0.482 0.517 0.000
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.482 0.517 0.000
M07.24 Psoriatic spondylitis (Hand)
0.482 0.517 0.000
M07.23 Psoriatic spondylitis (Forearm)
0.482 0.517 0.000
M07.22 Psoriatic spondylitis (Upper arm)
0.482 0.517 0.000
M07.21 Psoriatic spondylitis (Shoulder region)
0.482 0.517 0.000
M07.20 Psoriatic spondylitis (Multiple sites)
0.482 0.517 0.000
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)
0.482 0.517 0.000
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)
0.482 0.517 0.000
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)
0.482 0.517 0.000
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)
0.482 0.517 0.000
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)
0.482 0.517 0.000
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)
0.482 0.517 0.000
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)
0.482 0.517 0.000
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)
0.482 0.517 0.000
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)
0.482 0.517 0.000
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)
0.482 0.517 0.000
M07.59 Arthropathy in ulcerative colitis (Site unspecified)
0.482 0.517 0.000
M07.58 Arthropathy in ulcerative colitis (Other)
0.482 0.517 0.000
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)
0.482 0.517 0.000
M07.56 Arthropathy in ulcerative colitis (Lower leg)
0.482 0.517 0.000
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)
0.482 0.517 0.000
M07.54 Arthropathy in ulcerative colitis (Hand)
0.482 0.517 0.000
M07.53 Arthropathy in ulcerative colitis (Forearm)
0.482 0.517 0.000
M07.52 Arthropathy in ulcerative colitis (Upper arm)
0.482 0.517 0.000
M07.51 Arthropathy in ulcerative colitis (Shoulder region)
0.482 0.517 0.000
M07.50 Arthropathy in ulcerative colitis (Multiple sites)
0.482 0.517 0.000
M07.69 Other enteropathic arthropathies (Site unspecified)
0.482 0.517 0.000
M07.68 Other enteropathic arthropathies (Other)
0.482 0.517 0.000
M07.67 Other enteropathic arthropathies (Ankle and foot)
0.482 0.517 0.000
M07.66 Other enteropathic arthropathies (Lower leg)
0.482 0.517 0.000
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)
0.482 0.517 0.000
M07.64 Other enteropathic arthropathies (Hand)
0.482 0.517 0.000
M07.63 Other enteropathic arthropathies (Forearm)
0.482 0.517 0.000
M07.62 Other enteropathic arthropathies (Upper arm)
0.482 0.517 0.000
M07.61 Other enteropathic arthropathies (Shoulder region)
0.482 0.517 0.000
M07.60 Other enteropathic arthropathies (Multiple sites)
0.482 0.517 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.481 0.519 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.002 0.523 0.475
D52.8 Other folate deficiency anaemias
0.000 0.526 0.474
D52.1 Drug-induced folate deficiency anaemia
0.000 0.526 0.474
D52.0 Dietary folate deficiency anaemia
0.000 0.526 0.474
C83.0 Small cell (diffuse)
0.472 0.527 0.001
D59 Acquired haemolytic anaemia
0.002 0.528 0.470
Chapter II Neoplasms
0.463 0.531 0.006
M00-M03 Infectious arthropathies
0.467 0.533 0.000
M80-M85 Disorders of bone density and structure
0.456 0.544 0.000
C88.9 Malignant immunoproliferative disease, unspecified
0.454 0.546 0.001
C88.7 Other malignant immunoproliferative diseases
0.454 0.546 0.001
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.454 0.546 0.001
C88.3 Immunoproliferative small intestinal disease
0.454 0.546 0.001
C88.2 Gamma heavy chain disease
0.454 0.546 0.001
C88.1 Alpha heavy chain disease
0.454 0.546 0.001
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.451 0.547 0.002
M11.96 Crystal arthropathy, unspecified (Lower leg)
0.452 0.548 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.548 0.452
C95.7 Other leukaemia of unspecified cell type
0.450 0.549 0.001
C95.2 Subacute leukaemia of unspecified cell type
0.450 0.549 0.001
C95.1 Chronic leukaemia of unspecified cell type
0.450 0.549 0.001
C95.0 Acute leukaemia of unspecified cell type
0.450 0.549 0.001
C84.9 Mature T/NK-cell lymphoma, unspecified
0.449 0.551 0.001
C84.8 Cutaneous T-cell lymphoma, unspecified
0.449 0.551 0.001
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.449 0.551 0.001
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.449 0.551 0.001
C84.3 Lymphoepithelioid lymphoma
0.449 0.551 0.001
C84.2 T-zone lymphoma
0.449 0.551 0.001
C84.1 Sezary's diease
0.449 0.551 0.001
C84.0 Mycosis fungoides
0.449 0.551 0.001
M60-M63 Disorders of muscles
0.448 0.552 0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.448 0.552 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.444 0.556 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.443 0.556 0.000
D84 Other immunodeficiencies
0.003 0.557 0.440
C90 Multiple myeloma and malignant plasma cell neoplasms
0.443 0.557 0.001
C73 Malignant neoplasm of thyroid gland
0.440 0.559 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.560 0.440
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.434 0.565 0.000
C43.7 Malignant melanoma of lower limb, including hip
0.432 0.568 0.000
C84.5 Other and unspecified T-cell lymphomas
0.431 0.568 0.000
E10.1 With ketoacidosis
0.000 0.571 0.429
M67 Other disorders of synovium and tendon
0.428 0.572 0.000
M40 Kyphosis and lordosis
0.427 0.573 0.000
C81.1 Nodular sclerosis
0.426 0.573 0.000
C92 Myeloid leukaemia
0.425 0.574 0.001
C43.8 Overlapping malignant melanoma of skin
0.424 0.576 0.000
C43.1 Malignant melanoma of eyelid, including canthus
0.424 0.576 0.000
C43.0 Malignant melanoma of lip
0.424 0.576 0.000
E10.3 With ophthalmic complications
0.000 0.577 0.423
M46.2 Osteomyelitis of vertebra
0.419 0.581 0.000
M91-M94 Chondropathies
0.419 0.581 0.000
C91.5 Adult T-cell leukaemia
0.413 0.585 0.002
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.414 0.586 0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.413 0.587 0.000
C84.4 Peripheral T-cell lymphoma
0.410 0.590 0.001
D59.1 Other autoimmune haemolytic anaemias
0.001 0.590 0.409
M65.1 Other infective (teno)synovitis
0.408 0.592 0.000
C43.2 Malignant melanoma of ear and external auricular canal
0.408 0.592 0.000
M49.5 Collapsed vertebra in diseases classified elsewhere
0.407 0.593 0.000
C81.7 Other Hodgkin's disease
0.405 0.594 0.001
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.405 0.594 0.001
C81.3 Lymphocytic depletion
0.405 0.594 0.001
C81.2 Mixed cellularity
0.405 0.594 0.001
C81.0 Lymphocytic predominance
0.405 0.594 0.001
M46.9 Inflammatory spondylopathy, unspecified
0.406 0.594 0.000
M65.8 Other synovitis and tenosynovitis
0.406 0.594 0.000
M13.1 Monoarthritis, not elsewhere classified
0.405 0.595 0.000
J45.0 Predominantly allergic asthma
0.003 0.596 0.401
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.401 0.597 0.002
M11.2 Other chondrocalcinosis
0.402 0.598 0.000
C88.0 Waldenstrom's macroglobulinaemia
0.401 0.599 0.001
D57 Sickle-cell disorders
0.003 0.599 0.398
D55 Anaemia due to enzyme disorders
0.003 0.599 0.398
D81.9 Combined immunodeficiency, unspecified
0.002 0.599 0.399
D81.8 Other combined immunodeficiencies
0.002 0.599 0.399
D81.7 Major histocompatibility complex class II deficiency
0.002 0.599 0.399

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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