TreeWAS – Variant ID: rs6936539

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	0.000	0.000	1.000
E83.1 Disorders of iron metabolism	0.000	0.000	1.000
E10 Insulin-dependent diabetes mellitus	0.000	0.656	0.344
E10.9 Without complications	0.000	0.660	0.340
K90 Intestinal malabsorption	0.000	0.675	0.325
E10.4 With neurological complications	0.000	0.680	0.320
E10.5 With peripheral circulatory complications	0.000	0.684	0.316
E10.6 With other specified complications	0.000	0.690	0.310
E10.8 With unspecified complications	0.000	0.710	0.289
E83 Disorders of mineral metabolism	0.000	0.726	0.273
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.733	0.267
E10-E14 Diabetes mellitus	0.000	0.738	0.262
E10.2 With renal complications	0.000	0.744	0.256
E10.1 With ketoacidosis	0.000	0.745	0.255
E10.7 With multiple complications	0.000	0.753	0.247
K90.3 Pancreatic steatorrhoea	0.000	0.767	0.233
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.767	0.233
K90.1 Tropical sprue	0.000	0.767	0.233
E10.0 With coma	0.000	0.767	0.232
K90.8 Other intestinal malabsorption	0.000	0.776	0.224
E13 Other specified diabetes mellitus	0.000	0.779	0.221
E10.3 With ophthalmic complications	0.000	0.780	0.220
E70-E90 Metabolic disorders	0.000	0.793	0.207
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.794	0.206
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.804	0.196
E83.8 Other disorders of mineral metabolism	0.000	0.804	0.196
E83.2 Disorders of zinc metabolism	0.000	0.804	0.196
E83.0 Disorders of copper metabolism	0.000	0.804	0.196
E13.9 Without complications	0.000	0.806	0.194
E14 Unspecified diabetes mellitus	0.000	0.807	0.193
E12 Malnutrition-related diabetes mellitus	0.000	0.812	0.188
E14.3 With ophthalmic complications	0.000	0.815	0.185
E88 Other metabolic disorders	0.000	0.827	0.173
E40-E46 Malnutrition	0.000	0.828	0.172
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.832	0.168
E85 Amyloidosis	0.000	0.837	0.163
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.838	0.162
E13.8 With unspecified complications	0.000	0.841	0.159
E13.7 With multiple complications	0.000	0.841	0.159
E13.6 With other specified complications	0.000	0.841	0.159
E13.5 With peripheral circulatory complications	0.000	0.841	0.159
E13.4 With neurological complications	0.000	0.841	0.159
E13.2 With renal complications	0.000	0.841	0.159
E13.1 With ketoacidosis	0.000	0.841	0.159
E13.0 With coma	0.000	0.841	0.159
E13.3 With ophthalmic complications	0.000	0.845	0.155
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.849	0.151
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.851	0.149
E84 Cystic fibrosis	0.000	0.852	0.148
E77 Disorders of glycoprotein metabolism	0.000	0.852	0.148
E76 Disorders of glycosaminoglycan metabolism	0.000	0.852	0.148
E72 Other disorders of amino-acid metabolism	0.000	0.852	0.148
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.852	0.148
E70 Disorders of aromatic amino-acid metabolism	0.000	0.852	0.148
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.852	0.148
E46 Unspecified protein-energy malnutrition	0.000	0.853	0.147
E14.5 With peripheral circulatory complications	0.000	0.856	0.144
E16 Other disorders of pancreatic internal secretion	0.000	0.859	0.141
E65-E68 Obesity and other hyperalimentation	0.000	0.860	0.140
E14.7 With multiple complications	0.000	0.861	0.139
E14.6 With other specified complications	0.000	0.861	0.139
E14.2 Withrenal complications	0.000	0.861	0.139
E14.0 With coma	0.000	0.861	0.139
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.862	0.138
E83.3 Disorders of phosphorus metabolism	0.000	0.865	0.135
E12.9 Without complications	0.000	0.865	0.135
E12.8 With unspecified complications	0.000	0.865	0.135
E12.7 With multiple complications	0.000	0.865	0.135
E12.6 With other specified complications	0.000	0.865	0.135
E12.5 With peripheral circulatory complications	0.000	0.865	0.135
E12.4 With neurological complications	0.000	0.865	0.135
E12.3 With ophthalmic complications	0.000	0.865	0.135
E12.2 With renal complications	0.000	0.865	0.135
E12.1 With ketoacidosis	0.000	0.865	0.135
E12.0 With coma	0.000	0.865	0.135
E85.9 Amyloidosis, unspecified	0.000	0.865	0.134
E79 Disorders of purine and pyrimidine metabolism	0.000	0.866	0.134
E14.4 With neurological complications	0.000	0.866	0.134
E88.2 Lipomatosis, not elsewhere classified	0.000	0.867	0.133
E89.2 Postprocedural hypoparathyroidism	0.000	0.868	0.132
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.868	0.132
E88.8 Other specified metabolic disorders	0.000	0.868	0.131
E16.2 Hypoglycaemia, unspecified	0.000	0.872	0.128
E89.0 Postprocedural hypothyroidism	0.000	0.873	0.127
E83.4 Disorders of magnesium metabolism	0.000	0.874	0.126
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.874	0.126
E88.3 Tumour lysis syndrome	0.000	0.875	0.125
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.877	0.123
E45 Retarded development following protein-energy malnutrition	0.000	0.877	0.123
E43 Unspecified severe protein-energy malnutrition	0.000	0.877	0.123
E42 Marasmic kwashiorkor	0.000	0.877	0.123
E41 Nutritional marasmus	0.000	0.877	0.123
E40 Kwashiorkor	0.000	0.877	0.123
E85.4 Organ-limited amyloidosis	0.000	0.877	0.123
E89.4 Postprocedural ovarian failure	0.000	0.878	0.121
E15 Nondiabetic hypoglycaemic coma	0.000	0.879	0.120
E65 Localised adiposity	0.000	0.881	0.119
E14.1 With ketoacidosis	0.000	0.882	0.117
E85.8 Other amyloidosis	0.000	0.883	0.117
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.883	0.117
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.883	0.117
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.883	0.117
E74 Other disorders of carbohydrate metabolism	0.000	0.883	0.117
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.883	0.117
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.883	0.117
E89.5 Postprocedural testicular hypofunction	0.000	0.883	0.117
E89.1 Postprocedural hypoinsulinaemia	0.000	0.883	0.117
K90.9 Intestinal malabsorption, unspecified	0.000	0.883	0.116
E88.9 Metabolic disorder, unspecified	0.000	0.884	0.115
E80.4 Gilbert's syndrome	0.000	0.885	0.115
E14.8 With unspecified complications	0.000	0.885	0.114
E11 Non-insulin-dependent diabetes mellitus	0.000	0.888	0.112
E75.5 Other lipid storage disorders	0.000	0.888	0.112
E73 Lactose intolerance	0.000	0.891	0.108
E75.6 Lipid storage disorder, unspecified	0.000	0.891	0.109
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.891	0.109
E75.3 Sphingolipidosis, unspecified	0.000	0.891	0.109
E75.2 Other sphingolipidosis	0.000	0.891	0.109
E75.1 Other gangliosidosis	0.000	0.891	0.109
E75.0 GM2 gangliosidosis	0.000	0.891	0.109
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.893	0.107
E80.5 Crigler-Najjar syndrome	0.000	0.893	0.107
E80.3 Defects of catalase and peroxydase	0.000	0.893	0.107
E80.1 Porphyria cutanea tarda	0.000	0.893	0.107
E80.0 Hereditary erythropoietic porphyria	0.000	0.893	0.107
E85.3 Secondary systemic amyloidosis	0.000	0.893	0.107
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.893	0.106
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.893	0.106
E70.3 Albinism	0.000	0.893	0.106
E70.2 Disorders of tyrosine metabolism	0.000	0.893	0.106
E70.1 Other hyperphenylalaninaemias	0.000	0.893	0.106
E70.0 Classical phenylketonuria	0.000	0.893	0.106
E71.3 Disorders of fatty-acid metabolism	0.000	0.893	0.106
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.893	0.106
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.893	0.106
E71.0 Maple-syrup-urine disease	0.000	0.893	0.106
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.893	0.106
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.893	0.106
E72.5 Disorders of glycine metabolism	0.000	0.893	0.106
E72.4 Disorders of ornithine metabolism	0.000	0.893	0.106
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.893	0.106
E72.2 Disorders of urea cycle metabolism	0.000	0.893	0.106
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.893	0.106
E72.0 Disorders of amino-acid transport	0.000	0.893	0.106
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.893	0.106
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.893	0.106
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.893	0.106
E76.2 Other mucopolysaccharidoses	0.000	0.893	0.106
E76.1 Mucopolysaccharidosis, type II	0.000	0.893	0.106
E76.0 Mucopolysaccharidosis, type I	0.000	0.893	0.106
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.893	0.106
E77.8 Other disorders of glycoprotein metabolism	0.000	0.893	0.106
E77.1 Defects in glycoprotein degradation	0.000	0.893	0.106
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.893	0.106
E84.9 Cystic fibrosis, unspecified	0.000	0.893	0.106
E84.8 Cystic fibrosis with other manifestations	0.000	0.893	0.106
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.893	0.106
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.893	0.106
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.896	0.104
E80.2 Other porphyria	0.000	0.897	0.103
E80.6 Other disorders of bilirubin metabolism	0.000	0.898	0.102
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.899	0.101
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.899	0.101
E16.4 Abnormal secretion of gastrin	0.000	0.899	0.101
E16.3 Increased secretion of glucagon	0.000	0.899	0.101
E67 Other hyperalimentation	0.000	0.899	0.100
E68 Sequelae of hyperalimentation	0.000	0.899	0.100
E83.5 Disorders of calcium metabolism	0.000	0.903	0.097
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.903	0.096
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.903	0.096
E79.1 Lesch-Nyhan syndrome	0.000	0.903	0.096
E11.5 With peripheral circulatory complications	0.000	0.906	0.094
E44.1 Mild protein-energy malnutrition	0.000	0.911	0.088
E44.0 Moderate protein-energy malnutrition	0.000	0.911	0.088
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.913	0.087
E11.0 With coma	0.000	0.914	0.086
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.915	0.085
E20-E35 Disorders of other endocrine glands	0.000	0.916	0.084
E00-E07 Disorders of thyroid gland	0.000	0.916	0.084
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.916	0.084
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.916	0.084
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.916	0.084
E74.2 Disorders of galactose metabolism	0.000	0.916	0.084
E74.1 Disorders of fructose metabolism	0.000	0.916	0.084
E11.8 With unspecified complications	0.000	0.916	0.084
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.918	0.082
E11.1 With ketoacidosis	0.000	0.918	0.082
E11.7 With multiple complications	0.000	0.919	0.080
E11.2 With renal complications	0.000	0.920	0.080
E73.8 Other lactose intolerance	0.000	0.922	0.078
E73.1 Secondary lactase deficiency	0.000	0.922	0.078
E73.0 Congenital lactase deficiency	0.000	0.922	0.078
E74.0 Glycogen storage disease	0.000	0.923	0.077
E89.3 Postprocedural hypopituitarism	0.000	0.923	0.077
E87 Other disorders of fluid, electrolyte and acid-base balance	0.000	0.923	0.077
E11.6 With other specified complications	0.000	0.923	0.077
E16.1 Other hypoglycaemia	0.000	0.923	0.076
E11.4 With neurological complications	0.000	0.924	0.076
E67.8 Other specified hyperalimentation	0.000	0.928	0.072
E67.3 Hypervitaminosis D	0.000	0.928	0.072
E67.2 Megavitamin-B6 syndrome	0.000	0.928	0.072
E67.1 Hypercarotenaemia	0.000	0.928	0.072
E67.0 Hypervitaminosis A	0.000	0.928	0.072
E78.4 Other hyperlipidaemia	0.000	0.929	0.071
E87.3 Alkalosis	0.000	0.931	0.069
E50-E64 Other nutritional deficiencies	0.000	0.931	0.069
E07 Other disorders of thyroid	0.000	0.934	0.066
E78.6 Lipoprotein deficiency	0.000	0.934	0.066
E29 Testicular dysfunction	0.000	0.935	0.065
E87.0 Hyperosmolality and hypernatraemia	0.000	0.935	0.065
E28 Ovarian dysfunction	0.000	0.936	0.064
E20 Hypoparathyroidism	0.000	0.936	0.064
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.936	0.063
E26 Hyperaldosteronism	0.000	0.937	0.063
E78.3 Hyperchylomicronaemia	0.000	0.937	0.063
E04 Other non-toxic goitre	0.000	0.939	0.061
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.939	0.061
E32 Diseases of thymus	0.000	0.939	0.061
E31 Polyglandular dysfunction	0.000	0.939	0.061
E30 Disorders of puberty, not elsewhere classified	0.000	0.939	0.061
E25 Adrenogenital disorders	0.000	0.939	0.061
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.939	0.060
E00 Congenital iodine-deficiency syndrome	0.000	0.939	0.060
E23 Hypofunction and other disorders of pituitary gland	0.000	0.940	0.060
E78.1 Pure hyperglyceridaemia	0.000	0.941	0.059
E24 Cushing's syndrome	0.000	0.942	0.057
E28.2 Polycystic ovarian syndrome	0.000	0.943	0.057
E87.2 Acidosis	0.000	0.944	0.056
E06 Thyroiditis	0.000	0.944	0.056
E78.2 Mixed hyperlipidaemia	0.000	0.944	0.056
E87.7 Fluid overload	0.000	0.944	0.056
E87.4 Mixed disorder of acid-base balance	0.000	0.945	0.055
E23.2 Diabetes insipidus	0.000	0.945	0.055
E07.9 Disorder of thyroid, unspecified	0.000	0.945	0.055
E34 Other endocrine disorders	0.000	0.945	0.055
E04.9 Non-toxic goitre, unspecified	0.000	0.945	0.055
E11.3 With ophthalmic complications	0.000	0.946	0.054
E03 Other hypothyroidism	0.000	0.947	0.053
E27 Other disorders of adrenal gland	0.000	0.948	0.052
E29.1 Testicular hypofunction	0.000	0.948	0.052
E66 Obesity	0.000	0.949	0.051
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.950	0.049
E63 Other nutritional deficiencies	0.000	0.950	0.049
E56 Other vitamin deficiencies	0.000	0.950	0.049
E50 Vitamin A deficiency	0.000	0.950	0.049
E60 Dietary zinc deficiency	0.000	0.950	0.049
E59 Dietary selenium deficiency	0.000	0.950	0.049
E54 Ascorbic acid deficiency	0.000	0.950	0.049
E52 Niacin deficiency [pellagra]	0.000	0.950	0.049
E20.9 Hypoparathyroidism, unspecified	0.000	0.950	0.049
E58 Dietary calcium deficiency	0.000	0.951	0.049
E27.1 Primary adrenocortical insufficiency	0.000	0.951	0.049
E26.0 Primary hyperaldosteronism	0.000	0.952	0.048
E24.2 Drug-induced Cushing's syndrome	0.000	0.952	0.048
E07.1 Dyshormogenetic goitre	0.000	0.952	0.048
E07.0 Hypersecretion of calcitonin	0.000	0.952	0.048
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.952	0.048
E87.5 Hyperkalaemia	0.000	0.953	0.047
E03.8 Other specified hypothyroidism	0.000	0.953	0.047
E29.9 Testicular dysfunction, unspecified	0.000	0.953	0.047
E29.8 Other testicular dysfunction	0.000	0.953	0.047
E29.0 Testicular hyperfunction	0.000	0.953	0.047
E04.0 Non-toxic diffuse goitre	0.000	0.954	0.046
E28.9 Ovarian dysfunction, unspecified	0.000	0.954	0.046
E28.8 Other ovarian dysfunction	0.000	0.954	0.046
E28.1 Androgen excess	0.000	0.954	0.046
E28.0 Oestrogen excess	0.000	0.954	0.046
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.954	0.046
E20.8 Other hypoparathyroidism	0.000	0.954	0.046
E20.1 Pseudohypoparathyroidism	0.000	0.954	0.046
E20.0 Idiopathic hypoparathyroidism	0.000	0.954	0.046
E51 Thiamine deficiency	0.000	0.954	0.045
E26.9 Hyperaldosteronism, unspecified	0.000	0.954	0.045
E26.8 Other hyperaldosteronism	0.000	0.954	0.045
E26.1 Secondary hyperaldosteronism	0.000	0.954	0.045
E53 Deficiency of other B group vitamins	0.000	0.955	0.045
E07.8 Other specified disorders of thyroid	0.000	0.955	0.045
E04.8 Other specified non-toxic goitre	0.000	0.956	0.044
E25.9 Adrenogenital disorder, unspecified	0.000	0.956	0.044
E25.8 Other adrenogenital disorders	0.000	0.956	0.044
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.956	0.044
E30.9 Disorder of puberty, unspecified	0.000	0.956	0.044
E30.8 Other disorders of puberty	0.000	0.956	0.044
E30.1 Precocious puberty	0.000	0.956	0.044
E30.0 Delayed puberty	0.000	0.956	0.044
E31.9 Polyglandular dysfunction, unspecified	0.000	0.956	0.044
E31.8 Other polyglandular dysfunction	0.000	0.956	0.044
E31.1 Polyglandular hyperfunction	0.000	0.956	0.044
E31.0 Autoimmune polyglandular failure	0.000	0.956	0.044
E32.9 Disease of thymus, unspecified	0.000	0.956	0.044
E32.8 Other diseases of thymus	0.000	0.956	0.044
E32.1 Abscess of thymus	0.000	0.956	0.044
E32.0 Persistent hyperplasia of thymus	0.000	0.956	0.044
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.956	0.044
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.956	0.044
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.956	0.044
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.956	0.043
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.956	0.043
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.956	0.043
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.956	0.043
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.956	0.043
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.956	0.043
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.956	0.043
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.956	0.043
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.957	0.043
E23.1 Drug-induced hypopituitarism	0.000	0.957	0.043
E14.9 Without complications	0.000	0.957	0.043
E23.7 Disorder of pituitary gland, unspecified	0.000	0.958	0.042
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.958	0.042
E24.8 Other Cushing's syndrome	0.000	0.958	0.041
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.958	0.041
E24.3 Ectopic ACTH syndrome	0.000	0.958	0.041
E24.1 Nelson's syndrome	0.000	0.958	0.041
E06.3 Autoimmune thyroiditis	0.000	0.959	0.041
E06.5 Other chronic thyroiditis	0.000	0.960	0.040
E06.4 Drug-induced thyroiditis	0.000	0.960	0.040
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.960	0.040
E06.1 Subacute thyroiditis	0.000	0.960	0.040
E06.0 Acute thyroiditis	0.000	0.960	0.040
E34.5 Androgen resistance syndrome	0.000	0.960	0.039
E34.4 Constitutional tall stature	0.000	0.960	0.039
E34.3 Short stature, not elsewhere classified	0.000	0.960	0.039
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.960	0.039
E34.1 Other hypersecretion of intestinal hormones	0.000	0.960	0.039
E55 Vitamin D deficiency	0.000	0.961	0.039
E34.9 Endocrine disorder, unspecified	0.000	0.961	0.039
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.961	0.039
E73.9 Lactose intolerance, unspecified	0.001	0.961	0.038
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.000	0.961	0.039
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.961	0.038
E34.8 Other specified endocrine disorders	0.000	0.962	0.038
E03.5 Myxoedema coma	0.000	0.962	0.038
E03.4 Atrophy of thyroid (acquired)	0.000	0.962	0.038
E03.3 Postinfectious hypothyroidism	0.000	0.962	0.038
E03.1 Congenital hypothyroidism without goitre	0.000	0.962	0.038
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.962	0.038
E24.0 Pituitary-dependent Cushing's disease	0.000	0.962	0.038
E27.5 Adrenomedullary hyperfunction	0.000	0.962	0.038
E27.0 Other adrenocortical overactivity	0.000	0.962	0.038
E21.3 Hyperparathyroidism, unspecified	0.000	0.963	0.037
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.963	0.037
E23.6 Other disorders of pituitary gland	0.000	0.963	0.037
E66.1 Drug-induced obesity	0.000	0.964	0.036
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.964	0.036
E04.2 Non-toxic multinodular goitre	0.000	0.964	0.036
E78.8 Other disorders of lipoprotein metabolism	0.000	0.964	0.036
E34.0 Carcinoid syndrome	0.000	0.964	0.036
E50.9 Vitamin A deficiency, unspecified	0.000	0.964	0.036
E50.8 Other manifestations of vitamin A deficiency	0.000	0.964	0.036
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.964	0.036
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.964	0.036
E50.5 Vitamin A deficiency with night blindness	0.000	0.964	0.036
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.964	0.036
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.964	0.036
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.964	0.036
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.964	0.036
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.964	0.036
E56.9 Vitamin deficiency, unspecified	0.000	0.964	0.036
E56.8 Deficiency of other vitamins	0.000	0.964	0.036
E56.1 Deficiency of vitamin K	0.000	0.964	0.036
E56.0 Deficiency of vitamin E	0.000	0.964	0.036
E63.9 Nutritional deficiency, unspecified	0.000	0.964	0.036
E63.8 Other specified nutritional deficiencies	0.000	0.964	0.036
E63.1 Imbalance of constituents of food intake	0.000	0.964	0.036
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.964	0.036
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.964	0.036
E64.8 Sequelae of other nutritional deficiencies	0.000	0.964	0.036
E64.3 Sequelae of rickets	0.000	0.964	0.036
E64.2 Sequelae of vitamin C deficiency	0.000	0.964	0.036
E64.1 Sequelae of vitamin A deficiency	0.000	0.964	0.036
E64.0 Sequelae of protein-energy malnutrition	0.000	0.964	0.036
E06.9 Thyroiditis, unspecified	0.000	0.965	0.035
E66.0 Obesity due to excess calories	0.000	0.965	0.035
E21.4 Other specified disorders of parathyroid gland	0.000	0.965	0.034
E21.2 Other hyperparathyroidism	0.000	0.965	0.034
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.966	0.034
E51.9 Thiamine deficiency, unspecified	0.000	0.967	0.033
E51.8 Other manifestations of thiamine deficiency	0.000	0.967	0.033
E51.1 Beriberi	0.000	0.967	0.033
E53.1 Pyridoxine deficiency	0.000	0.967	0.033
E53.0 Riboflavin deficiency	0.000	0.967	0.033
E53.9 Vitamin B deficiency, unspecified	0.000	0.967	0.032
E24.9 Cushing's syndrome, unspecified	0.000	0.968	0.032
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.968	0.031
E04.1 Non-toxic single thyroid nodule	0.000	0.970	0.030
E28.3 Primary ovarian failure	0.000	0.970	0.029
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.971	0.029
E51.2 Wernicke's encephalopathy	0.000	0.971	0.029
E27.2 Addisonian crisis	0.000	0.971	0.029
E53.8 Deficiency of other specified B group vitamins	0.000	0.971	0.029
E55.0 Rickets, active	0.000	0.972	0.028
E22 Hyperfunction of pituitary gland	0.000	0.972	0.028
E05.8 Other thyrotoxicosis	0.000	0.972	0.028
E05.5 Thyroid crisis or storm	0.000	0.973	0.027
E05.4 Thyrotoxicosis factitia	0.000	0.973	0.027
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.973	0.027
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.973	0.027
E86 Volume depletion	0.000	0.973	0.027
E61 Deficiency of other nutrient elements	0.001	0.974	0.025
E27.8 Other specified disorders of adrenal gland	0.000	0.976	0.024
E23.0 Hypopituitarism	0.000	0.976	0.024
E27.9 Disorder of adrenal gland, unspecified	0.000	0.978	0.022
K90-K93 Other diseases of the digestive system	0.000	0.979	0.021
E21.0 Primary hyperparathyroidism	0.000	0.979	0.021
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.980	0.020
E22.8 Other hyperfunction of pituitary gland	0.000	0.980	0.020
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.980	0.020
E61.9 Deficiency of nutrient element, unspecified	0.001	0.981	0.018
E61.8 Deficiency of other specified nutrient elements	0.001	0.981	0.018
E61.7 Deficiency of multiple nutrient elements	0.001	0.981	0.018
E61.6 Vanadium deficiency	0.001	0.981	0.018
E61.5 Molybdenum deficiency	0.001	0.981	0.018
E61.4 Chromium deficiency	0.001	0.981	0.018
E61.3 Manganese deficiency	0.001	0.981	0.018
E61.0 Copper deficiency	0.001	0.981	0.018
E22.1 Hyperprolactinaemia	0.000	0.982	0.018
E55.9 Vitamin D deficiency, unspecified	0.000	0.982	0.018
E66.9 Obesity, unspecified	0.000	0.982	0.018
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.984	0.015
R31 Unspecified haematuria	0.015	0.985	0.000
E61.2 Magnesium deficiency	0.001	0.985	0.014
E22.0 Acromegaly and pituitary gigantism	0.000	0.986	0.014
E87.6 Hypokalaemia	0.000	0.987	0.013
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.989	0.011
K93.1 Megacolon in Chagas' disease	0.000	0.989	0.011
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.989	0.011
G44.2 Tension-type headache	0.011	0.989	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.989	0.010
M41.9 Scoliosis, unspecified	0.009	0.991	0.000
M41.96 Scoliosis, unspecified (Lumbar region)	0.009	0.991	0.000
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.009	0.991	0.000
E05.9 Thyrotoxicosis, unspecified	0.000	0.991	0.009
M41.94 Scoliosis, unspecified (Thoracic region)	0.009	0.991	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.009	0.991	0.000
G31.8 Other specified degenerative diseases of nervous system	0.000	0.992	0.008
C71.2 Temporal lobe	0.008	0.992	0.000
E66.8 Other obesity	0.000	0.992	0.008
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.993	0.007
C71 Malignant neoplasm of brain	0.007	0.993	0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.007	0.993	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.007	0.993	0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.007	0.993	0.000
M41.92 Scoliosis, unspecified (Cervical region)	0.007	0.993	0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.007	0.993	0.000
C71.9 Brain, unspecified	0.007	0.993	0.000
G31.0 Circumscribed brain atrophy	0.000	0.993	0.007
E61.1 Iron deficiency	0.002	0.993	0.005
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.993	0.007
M79.10 Myalgia (Multiple sites)	0.006	0.993	0.000
C71.3 Parietal lobe	0.006	0.994	0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.006	0.994	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.006	0.994	0.000
G54.9 Nerve root and plexus disorder, unspecified	0.006	0.994	0.000
G44 Other headache syndromes	0.006	0.994	0.000
N04.9 Unspecified	0.000	0.994	0.006
C71.7 Brain stem	0.005	0.994	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.000	0.995	0.005
C71.8 Overlapping lesion of brain	0.005	0.995	0.000
C71.6 Cerebellum	0.005	0.995	0.000
C71.5 Cerebral ventricle	0.005	0.995	0.000
C71.0 Cerebrum, except lobes and ventricles	0.005	0.995	0.000
C71.1 Frontal lobe	0.005	0.995	0.000
G44.8 Other specified headache syndromes	0.005	0.995	0.000
M41 Scoliosis	0.005	0.995	0.000
M79.19 Myalgia (Site unspecified)	0.005	0.995	0.000
C71.4 Occipital lobe	0.004	0.995	0.000
G31.2 Degeneration of nervous system due to alcohol	0.000	0.995	0.004
M79.1 Myalgia	0.004	0.996	0.000
G44.1 Vascular headache, not elsewhere classified	0.004	0.996	0.000
G44.3 Chronic posttraumatic headache	0.004	0.996	0.000
M22.2 Patellofemoral disorders	0.004	0.996	0.000
R52.1 Chronic intractable pain	0.004	0.996	0.000
G44.0 Cluster headache syndrome	0.004	0.996	0.000
G44.4 Drug-induced headache, not elsewhere classified	0.004	0.996	0.000
K62.5 Haemorrhage of anus and rectum	0.004	0.996	0.000
G30-G32 Other degenerative diseases of the nervous system	0.000	0.996	0.004
E87.1 Hypo-osmolality and hyponatraemia	0.000	0.996	0.004
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome	0.004	0.996	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.004	0.996	0.000
M41.5 Other secondary scoliosis	0.003	0.996	0.000
M41.4 Neuromuscular scoliosis	0.003	0.996	0.000
M41.3 Thoracogenic scoliosis	0.003	0.996	0.000
M41.2 Other idiopathic scoliosis	0.003	0.996	0.000
M41.1 Juvenile idiopathic scoliosis	0.003	0.996	0.000
M41.0 Infantile idiopathic scoliosis	0.003	0.996	0.000
I31.9 Disease of pericardium, unspecified	0.000	0.996	0.004
M67.8 Other specified disorders of synovium and tendon	0.000	0.996	0.004
M71.12 Other infective bursitis (Upper arm)	0.004	0.996	0.000
G30 Alzheimer's disease	0.000	0.996	0.004
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.997	0.003
M79.15 Myalgia (Pelvic region and thigh)	0.003	0.997	0.000
M71.1 Other infective bursitis	0.003	0.997	0.000
M79.11 Myalgia (Shoulder region)	0.003	0.997	0.000
M79.17 Myalgia (Ankle and foot)	0.003	0.997	0.000
M79.14 Myalgia (Hand)	0.003	0.997	0.000
M79.13 Myalgia (Forearm)	0.003	0.997	0.000
M79.12 Myalgia (Upper arm)	0.003	0.997	0.000
Z97.5 Presence of (intra-uterine) contraceptive device	0.003	0.997	0.000
N50.1 Vascular disorders of male genital organs	0.000	0.997	0.003
G30.0 Alzheimer's disease with early onset	0.000	0.997	0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations