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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs6976769
log Bayes Factor = 3.00178
Chromosome 7   position 83,297,262  (GRCh37) Explore rs6976769 on Ensembl!
Variant rs6976769 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
# Top node
0.999 0.001 0.000
I20-I25 Ischaemic heart diseases
0.997 0.003 0.000
I25 Chronic ischaemic heart disease
0.975 0.025 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.972 0.028 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.970 0.030 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.946 0.054 0.000
E70-E90 Metabolic disorders
0.941 0.059 0.000
I21 Acute myocardial infarction
0.931 0.069 0.000
I20 Angina pectoris
0.917 0.083 0.000
I30-I52 Other forms of heart disease
0.904 0.096 0.000
I25.1 Atherosclerotic heart disease
0.896 0.104 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.894 0.106 0.000
R07 Pain in throat and chest
0.894 0.106 0.000
Chapter XIV Diseases of the genitourinary system
0.885 0.115 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.874 0.126 0.000
I21.9 Acute myocardial infarction, unspecified
0.871 0.129 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.842 0.158 0.000
Chapter XXI Factors influencing health status and contact with health services
0.840 0.160 0.000
Chapter V Mental and behavioural disorders
0.837 0.162 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.837 0.163 0.000
E78.0 Pure hypercholesterolaemia
0.835 0.165 0.000
I20.9 Angina pectoris, unspecified
0.827 0.173 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.825 0.175 0.000
Chapter VII Diseases of the eye and adnexa
0.822 0.178 0.000
I25.2 Old myocardial infarction
0.817 0.183 0.000
E86 Volume depletion
0.815 0.184 0.000
R07.2 Precordial pain
0.810 0.190 0.000
I60-I69 Cerebrovascular diseases
0.809 0.191 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.805 0.195 0.000
Chapter VIII Diseases of the ear and mastoid process
0.801 0.199 0.000
N17-N19 Renal failure
0.797 0.203 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.792 0.208 0.000
I10-I15 Hypertensive diseases
0.786 0.214 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.786 0.214 0.000
I95 Hypotension
0.785 0.215 0.000
R07.4 Chest pain, unspecified
0.775 0.225 0.000
E00-E07 Disorders of thyroid gland
0.774 0.225 0.000
I05-I09 Chronic rheumatic heart diseases
0.773 0.227 0.000
R47-R49 Symptoms and signs involving speech and voice
0.768 0.232 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.765 0.235 0.000
R00 Abnormalities of heart beat
0.764 0.236 0.000
N20-N23 Urolithiasis
0.758 0.242 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.757 0.243 0.000
I45 Other conduction disorders
0.755 0.245 0.000
Chapter X Diseases of the respiratory system
0.751 0.249 0.000
E78.5 Hyperlipidaemia, unspecified
0.750 0.250 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.750 0.250 0.000
E10-E14 Diabetes mellitus
0.749 0.251 0.000
R30-R39 Symptoms and signs involving the urinary system
0.744 0.256 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.743 0.257 0.000
H53-H54 Visual disturbances and blindness
0.739 0.261 0.000
R04 Haemorrhage from respiratory passages
0.736 0.264 0.000
I20.8 Other forms of angina pectoris
0.733 0.267 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.720 0.280 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
Chapter XXII Codes for special purposes
0.716 0.284 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.716 0.284 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.716 0.284 0.000
I24 Other acute ischaemic heart diseases
0.715 0.285 0.000
I23 Certain current complications following acute myocardial infarction
0.715 0.285 0.000
I22 Subsequent myocardial infarction
0.715 0.285 0.000
M20-M25 Other joint disorders
0.707 0.293 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.704 0.296 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.701 0.299 0.000
I47 Paroxysmal tachycardia
0.700 0.300 0.000
I25.6 Silent myocardial ischaemia
0.699 0.301 0.000
I25.5 Ischaemic cardiomyopathy
0.699 0.301 0.000
I25.4 Coronary artery aneurysm
0.699 0.301 0.000
I25.3 Aneurysm of heart
0.699 0.301 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.699 0.301 0.000
Chapter II Neoplasms
0.699 0.301 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.698 0.302 0.000
E50-E64 Other nutritional deficiencies
0.697 0.303 0.000
E40-E46 Malnutrition
0.697 0.303 0.000
E20-E35 Disorders of other endocrine glands
0.697 0.303 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.697 0.303 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.696 0.304 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.696 0.304 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.696 0.304 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.696 0.304 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.696 0.304 0.000
N18 Chronic renal failure
0.691 0.309 0.000
Chapter VI Diseases of the nervous system
0.689 0.311 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.688 0.312 0.000
I20.0 Unstable angina
0.686 0.314 0.000
I95.1 Orthostatic hypotension
0.684 0.316 0.000
I73 Other peripheral vascular diseases
0.683 0.317 0.000
I44 Atrioventricular and left bundle-branch block
0.683 0.317 0.000
E65-E68 Obesity and other hyperalimentation
0.682 0.317 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.682 0.318 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.681 0.319 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.681 0.319 0.000
R05 Cough
0.681 0.319 0.000
I34 Nonrheumatic mitral valve disorders
0.680 0.320 0.000
H53 Visual disturbances
0.679 0.321 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.678 0.322 0.000
R01 Cardiac murmurs and other cardiac sounds
0.678 0.322 0.000
R02 Gangrene, not elsewhere classified
0.678 0.322 0.000
I77 Other disorders of arteries and arterioles
0.675 0.325 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.674 0.325 0.000
E88 Other metabolic disorders
0.674 0.325 0.000
E85 Amyloidosis
0.674 0.325 0.000
E84 Cystic fibrosis
0.674 0.325 0.000
E83 Disorders of mineral metabolism
0.674 0.325 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.674 0.325 0.000
E79 Disorders of purine and pyrimidine metabolism
0.674 0.325 0.000
E77 Disorders of glycoprotein metabolism
0.674 0.325 0.000
E76 Disorders of glycosaminoglycan metabolism
0.674 0.325 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.674 0.325 0.000
E74 Other disorders of carbohydrate metabolism
0.674 0.325 0.000
E73 Lactose intolerance
0.674 0.325 0.000
E72 Other disorders of amino-acid metabolism
0.674 0.325 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.674 0.325 0.000
E70 Disorders of aromatic amino-acid metabolism
0.674 0.325 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.674 0.325 0.000
I50 Heart failure
0.672 0.328 0.000
I51 Complications and ill-defined descriptions of heart disease
0.670 0.330 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.669 0.331 0.000
I35 Nonrheumatic aortic valve disorders
0.668 0.332 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.667 0.332 0.000
I21.4 Acute subendocardial myocardial infarction
0.667 0.332 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.667 0.332 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.667 0.332 0.000
N17 Acute renal failure
0.663 0.337 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.661 0.339 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.660 0.340 0.000
I20.1 Angina pectoris with documented spasm
0.658 0.342 0.000
N25-N29 Other disorders of kidney and ureter
0.657 0.343 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.656 0.344 0.000
R07.3 Other chest pain
0.654 0.346 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.654 0.346 0.000
R06 Abnormalities of breathing
0.650 0.350 0.000
H65-H75 Diseases of middle ear and mastoid
0.649 0.351 0.000
M70-M79 Other soft tissue disorders
0.649 0.351 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.649 0.351 0.000
I45.1 Other and unspecified right bundle-branch block
0.648 0.352 0.000
I52 Other heart disorders in diseases classified elsewhere
0.648 0.352 0.000
I49 Other cardiac arrhythmias
0.648 0.352 0.000
I48 Atrial fibrillation and flutter
0.648 0.352 0.000
I46 Cardiac arrest
0.648 0.352 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.648 0.352 0.000
I42 Cardiomyopathy
0.648 0.352 0.000
I41 Myocarditis in diseases classified elsewhere
0.648 0.352 0.000
I40 Acute myocarditis
0.648 0.352 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.648 0.352 0.000
I37 Pulmonary valve disorders
0.648 0.352 0.000
I36 Nonrheumatic tricuspid valve disorders
0.648 0.352 0.000
I33 Acute and subacute endocarditis
0.648 0.352 0.000
I32 Pericarditis in diseases classified elsewhere
0.648 0.352 0.000
I31 Other diseases of pericardium
0.648 0.352 0.000
I30 Acute pericarditis
0.648 0.352 0.000
I38 Endocarditis, valve unspecified
0.648 0.352 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.646 0.354 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.644 0.356 0.000
I95.9 Hypotension, unspecified
0.644 0.356 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.643 0.356 0.000
N20 Calculus of kidney and ureter
0.642 0.358 0.000
Chapter XX External causes of morbidity and mortality
0.642 0.358 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.641 0.359 0.000
E78.8 Other disorders of lipoprotein metabolism
0.641 0.359 0.000
E78.6 Lipoprotein deficiency
0.641 0.359 0.000
E78.4 Other hyperlipidaemia
0.641 0.359 0.000
E78.3 Hyperchylomicronaemia
0.641 0.359 0.000
E78.2 Mixed hyperlipidaemia
0.641 0.359 0.000
E78.1 Pure hyperglyceridaemia
0.641 0.359 0.000
R07.1 Chest pain on breathing
0.641 0.359 0.000
R07.0 Pain in throat
0.641 0.359 0.000
M45-M49 Spondylopathies
0.634 0.366 0.000
N99-N99 Other disorders of the genitourinary system
0.634 0.366 0.000
N60-N64 Disorders of breast
0.634 0.366 0.000
N10-N16 Renal tubulo-interstitial diseases
0.634 0.366 0.000
N00-N08 Glomerular diseases
0.634 0.366 0.000
I10 Essential (primary) hypertension
0.634 0.366 0.000
E04 Other non-toxic goitre
0.632 0.368 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.631 0.369 0.000
I67 Other cerebrovascular diseases
0.629 0.370 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.628 0.372 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.627 0.373 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.627 0.373 0.000
I99 Other and unspecified disorders of circulatory system
0.627 0.373 0.000
M50-M54 Other dorsopathies
0.625 0.375 0.000
F30-F39 Mood [affective] disorders
0.624 0.376 0.000
R47 Speech disturbances, not elsewhere classified
0.623 0.377 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.622 0.378 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.620 0.380 0.000
Z86 Personal history of certain other diseases
0.617 0.383 0.000
Chapter I Certain infectious and parasitic diseases
0.616 0.384 0.000
J09-J18 Influenza and pneumonia
0.611 0.389 0.000
I08 Multiple valve diseases
0.611 0.389 0.000
M05-M14 Inflammatory polyarthropathies
0.610 0.389 0.000
R39 Other symptoms and signs involving the urinary system
0.610 0.390 0.000
R00.2 Palpitations
0.607 0.392 0.000
H53.2 Diplopia
0.606 0.394 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.604 0.396 0.000
I78 Diseases of capillaries
0.604 0.396 0.000
I74 Arterial embolism and thrombosis
0.604 0.396 0.000
I72 Other aneurysm
0.604 0.396 0.000
I71 Aortic aneurysm and dissection
0.604 0.396 0.000
I70 Atherosclerosis
0.604 0.396 0.000
F99-F99 Unspecified mental disorder
0.600 0.399 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.600 0.399 0.000
F80-F89 Disorders of psychological development
0.600 0.399 0.000
F70-F79 Mental retardation
0.600 0.399 0.000
F60-F69 Disorders of adult personality and behaviour
0.600 0.399 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.600 0.399 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.600 0.399 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.600 0.399 0.000
S80-S89 Injuries to the knee and lower leg
0.600 0.400 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.600 0.400 0.000
M91-M94 Chondropathies
0.600 0.400 0.000
M86-M90 Other osteopathies
0.600 0.400 0.000
M65-M68 Disorders of synovium and tendon
0.600 0.400 0.000
M60-M63 Disorders of muscles
0.600 0.400 0.000
M40-M43 Deforming dorsopathies
0.600 0.400 0.000
M00-M03 Infectious arthropathies
0.600 0.400 0.000
R04.0 Epistaxis
0.598 0.402 0.000
F41 Other anxiety disorders
0.598 0.402 0.000
Z95.1 Presence of aortocoronary bypass graft
0.595 0.405 0.000
H40-H42 Glaucoma
0.594 0.406 0.000
N23 Unspecified renal colic
0.592 0.408 0.000
H90-H95 Other disorders of ear
0.590 0.410 0.000
I63 Cerebral infarction
0.590 0.410 0.000
H55-H59 Other disorders of eye and adnexa
0.590 0.410 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.590 0.410 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.590 0.410 0.000
H43-H45 Disorders of vitreous body and globe
0.590 0.410 0.000
H30-H36 Disorders of choroid and retina
0.590 0.410 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.590 0.410 0.000
H10-H13 Disorders of conjunctiva
0.590 0.410 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.590 0.410 0.000
M20 Acquired deformities of fingers and toes
0.588 0.412 0.000
M25 Other joint disorders, not elsewhere classified
0.585 0.415 0.000
E14 Unspecified diabetes mellitus
0.583 0.417 0.000
R00.1 Bradycardia, unspecified
0.583 0.417 0.000
Z86.7 Personal history of diseases of the circulatory system
0.582 0.418 0.000
I69 Sequelae of cerebrovascular disease
0.580 0.420 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.580 0.420 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.580 0.420 0.000
I62 Other nontraumatic intracranial haemorrhage
0.580 0.420 0.000
I61 Intracerebral haemorrhage
0.580 0.420 0.000
I60 Subarachnoid haemorrhage
0.580 0.420 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.580 0.420 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.578 0.422 0.000
Z92 Personal history of medical treatment
0.578 0.422 0.000
I73.0 Raynaud's syndrome
0.577 0.423 0.000
N18.9 Chronic renal failure, unspecified
0.577 0.423 0.000
J95-J99 Other diseases of the respiratory system
0.576 0.423 0.000
S40-S49 Injuries to the shoulder and upper arm
0.575 0.425 0.000
H80-H83 Diseases of inner ear
0.574 0.425 0.000
H60-H62 Diseases of external ear
0.574 0.425 0.000
N19 Unspecified renal failure
0.571 0.429 0.000
R03.1 Nonspecific low blood-pressure reading
0.568 0.432 0.000
N17.9 Acute renal failure, unspecified
0.567 0.433 0.000
H53.8 Other visual disturbances
0.566 0.433 0.000
M80-M85 Disorders of bone density and structure
0.565 0.435 0.000
S50-S59 Injuries to the elbow and forearm
0.564 0.436 0.000
I15 Secondary hypertension
0.564 0.436 0.000
I13 Hypertensive heart and renal disease
0.564 0.436 0.000
I12 Hypertensive renal disease
0.564 0.436 0.000
I11 Hypertensive heart disease
0.564 0.436 0.000
R27 Other lack of coordination
0.563 0.436 0.000
R26 Abnormalities of gait and mobility
0.563 0.436 0.000
R25 Abnormal involuntary movements
0.563 0.436 0.000
S70-S79 Injuries to the hip and thigh
0.563 0.437 0.000
I95.8 Other hypotension
0.563 0.437 0.000
I95.2 Hypotension due to drugs
0.563 0.437 0.000
I95.0 Idiopathic hypotension
0.563 0.437 0.000
E11 Non-insulin-dependent diabetes mellitus
0.561 0.439 0.000
N18.3 Chronic kidney disease, stage 3
0.561 0.439 0.000
E03 Other hypothyroidism
0.557 0.442 0.000
Z87 Personal history of other diseases and conditions
0.557 0.443 0.000
J90-J94 Other diseases of pleura
0.557 0.443 0.000
Z80 Family history of malignant neoplasm
0.556 0.444 0.000
S00-S09 Injuries to the head
0.556 0.444 0.000
E07 Other disorders of thyroid
0.555 0.445 0.000
E06 Thyroiditis
0.555 0.445 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.555 0.445 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.555 0.445 0.000
E00 Congenital iodine-deficiency syndrome
0.555 0.445 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.555 0.445 0.000
I77.1 Stricture of artery
0.555 0.445 0.000
I47.1 Supraventricular tachycardia
0.555 0.445 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.554 0.445 0.000
I09 Other rheumatic heart diseases
0.554 0.446 0.000
I07 Rheumatic tricuspid valve diseases
0.554 0.446 0.000
I06 Rheumatic aortic valve diseases
0.554 0.446 0.000
I05 Rheumatic mitral valve diseases
0.554 0.446 0.000
O80-O84 Delivery
0.554 0.446 0.000
R11 Nausea and vomiting
0.552 0.448 0.000
R49 Voice disturbances
0.551 0.449 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.551 0.449 0.000
D10-D36 Benign neoplasms
0.551 0.449 0.000
R50-R69 General symptoms and signs
0.550 0.450 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.548 0.452 0.000
T79-T79 Certain early complications of trauma
0.548 0.452 0.000
T66-T78 Other and unspecified effects of external causes
0.548 0.452 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.548 0.452 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.548 0.452 0.000
T33-T35 Frostbite
0.548 0.452 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.548 0.452 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.548 0.452 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.548 0.452 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.548 0.452 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.548 0.452 0.000
T00-T07 Injuries involving multiple body regions
0.548 0.452 0.000
S90-S99 Injuries to the ankle and foot
0.548 0.452 0.000
S60-S69 Injuries to the wrist and hand
0.548 0.452 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.548 0.452 0.000
S20-S29 Injuries to the thorax
0.548 0.452 0.000
S10-S19 Injuries to the neck
0.548 0.452 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.547 0.452 0.000
R00.0 Tachycardia, unspecified
0.547 0.452 0.000
D50-D53 Nutritional anaemias
0.545 0.455 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.544 0.456 0.000
N21 Calculus of lower urinary tract
0.544 0.456 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.543 0.457 0.000
Z98 Other postsurgical states
0.543 0.457 0.000
Z97 Presence of other devices
0.543 0.457 0.000
Z94 Transplanted organ and tissue status
0.543 0.457 0.000
Z93 Artificial opening status
0.543 0.457 0.000
Z89 Acquired absence of limb
0.543 0.457 0.000
Z84 Family history of other conditions
0.543 0.457 0.000
Z83 Family history of other specific disorders
0.543 0.457 0.000
Z81 Family history of mental and behavioural disorders
0.543 0.457 0.000
R33 Retention of urine
0.542 0.458 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.542 0.458 0.000
I45.9 Conduction disorder, unspecified
0.541 0.459 0.000
I45.8 Other specified conduction disorders
0.541 0.459 0.000
I45.6 Preexcitation syndrome
0.541 0.459 0.000
I45.5 Other specified heart block
0.541 0.459 0.000
I45.4 Nonspecific intraventricular block
0.541 0.459 0.000
I45.3 Trifascicular block
0.541 0.459 0.000
I45.2 Bifascicular block
0.541 0.459 0.000
I45.0 Right fascicular block
0.541 0.459 0.000
H71 Cholesteatoma of middle ear
0.540 0.460 0.000
O60-O75 Complications of labour and delivery
0.540 0.460 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.538 0.462 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.538 0.462 0.000
J60-J70 Lung diseases due to external agents
0.538 0.462 0.000
J00-J06 Acute upper respiratory infections
0.538 0.462 0.000
E13 Other specified diabetes mellitus
0.537 0.463 0.000
E12 Malnutrition-related diabetes mellitus
0.537 0.463 0.000
R15 Faecal incontinence
0.537 0.463 0.000
R31 Unspecified haematuria
0.535 0.465 0.000
R30 Pain associated with micturition
0.534 0.466 0.000
R36 Urethral discharge
0.534 0.466 0.000
R34 Anuria and oliguria
0.534 0.466 0.000
R32 Unspecified urinary incontinence
0.534 0.466 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.533 0.467 0.000
O85-O92 Complications predominantly related to the puerperium
0.533 0.467 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.533 0.467 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.533 0.467 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.533 0.467 0.000
O00-O08 Pregnancy with abortive outcome
0.533 0.467 0.000
H54 Blindness and low vision
0.530 0.470 0.000
E04.2 Non-toxic multinodular goitre
0.529 0.471 0.000
N20.0 Calculus of kidney
0.529 0.471 0.000
R04.9 Haemorrhage from respiratory passages, unspecified
0.528 0.472 0.000
R04.8 Haemorrhage from other sites in respiratory passages
0.528 0.472 0.000
R04.1 Haemorrhage from throat
0.528 0.472 0.000
I44.7 Left bundle-branch block, unspecified
0.525 0.475 0.000
N30-N39 Other diseases of urinary system
0.522 0.478 0.000
E10 Insulin-dependent diabetes mellitus
0.520 0.479 0.000
I26 Pulmonary embolism
0.520 0.480 0.000
R47.8 Other and unspecified speech disturbances
0.519 0.481 0.000
I34.0 Mitral (valve) insufficiency
0.519 0.481 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.519 0.481 0.000
M15-M19 Arthrosis
0.518 0.482 0.000
I28 Other diseases of pulmonary vessels
0.516 0.484 0.000
I27 Other pulmonary heart diseases
0.516 0.484 0.000
I50.0 Congestive heart failure
0.516 0.484 0.000
J20-J22 Other acute lower respiratory infections
0.515 0.485 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.515 0.485 0.000
I02 Rheumatic chorea
0.513 0.486 0.000
I01 Rheumatic fever with heart involvement
0.513 0.486 0.000
I00 Rheumatic fever without mention of heart involvement
0.513 0.486 0.000
P90-P96 Other disorders originating in the perinatal period
0.513 0.486 0.000
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn
0.513 0.486 0.000
P75-P78 Digestive system disorders of fetus and newborn
0.513 0.486 0.000
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn
0.513 0.486 0.000
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn
0.513 0.486 0.000
P35-P39 Infections specific to the perinatal period
0.513 0.486 0.000
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period
0.513 0.486 0.000
P10-P15 Birth trauma
0.513 0.486 0.000
P05-P08 Disorders related to length of gestation and fetal growth
0.513 0.486 0.000
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery
0.513 0.486 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.513 0.486 0.000
Q80-Q89 Other congenital malformations
0.513 0.486 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.513 0.486 0.000
Q60-Q64 Congenital malformations of the urinary system
0.513 0.486 0.000
Q50-Q56 Congenital malformations of genital organs
0.513 0.486 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.513 0.486 0.000
Q35-Q37 Cleft lip and cleft palate
0.513 0.486 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.513 0.486 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.513 0.486 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.513 0.486 0.000
Q00-Q07 Congenital malformations of the nervous system
0.513 0.486 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.513 0.486 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.513 0.486 0.000
L20-L30 Dermatitis and eczema
0.513 0.487 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.512 0.487 0.000
I22.8 Subsequent myocardial infarction of other sites
0.512 0.487 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.512 0.487 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.512 0.487 0.000
I23.8 Other current complications following acute myocardial infarction
0.512 0.487 0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.512 0.487 0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.512 0.487 0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.512 0.487 0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.512 0.487 0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.512 0.487 0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.512 0.487 0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.512 0.487 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.512 0.487 0.000
I24.8 Other forms of acute ischaemic heart disease
0.512 0.487 0.000
I24.1 Dressler's syndrome
0.512 0.487 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.512 0.487 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.512 0.488 0.000
F41.9 Anxiety disorder, unspecified
0.511 0.489 0.000
J18 Pneumonia, organism unspecified
0.511 0.489 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.510 0.489 0.000
J40-J47 Chronic lower respiratory diseases
0.510 0.489 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.509 0.490 0.000
N20.1 Calculus of ureter
0.508 0.491 0.000
R04.2 Haemoptysis
0.508 0.492 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.507 0.493 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.507 0.493 0.000
M35 Other systemic involvement of connective tissue
0.507 0.493 0.000
M34 Systemic sclerosis
0.507 0.493 0.000
M33 Dermatopolymyositis
0.507 0.493 0.000
M32 Systemic lupus erythematosus
0.507 0.493 0.000
M31 Other necrotising vasculopathies
0.507 0.493 0.000
M30 Polyarteritis nodosa and related conditions
0.507 0.493 0.000
M24 Other specific joint derangements
0.507 0.493 0.000
M22 Disorders of patella
0.507 0.493 0.000
M21 Other acquired deformities of limbs
0.507 0.493 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.504 0.495 0.000
R18 Ascites
0.504 0.495 0.000
R17 Unspecified jaundice
0.504 0.495 0.000
R14 Flatulence and related conditions
0.504 0.495 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.504 0.496 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.503 0.497 0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.503 0.497 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.503 0.497 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.503 0.497 0.000
Z82.3 Family history of stroke
0.503 0.497 0.000
Z82.2 Family history of deafness and hearing loss
0.503 0.497 0.000
Z82.1 Family history of blindness and visual loss
0.503 0.497 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.503 0.497 0.000
Z22 Carrier of infectious disease
0.502 0.497 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.502 0.498 0.000
I47.2 Ventricular tachycardia
0.502 0.498 0.000
I47.0 Reentry ventricular arrhythmia
0.502 0.498 0.000
I51.7 Cardiomegaly
0.502 0.498 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.502 0.498 0.000
R13 Dysphagia
0.502 0.498 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.501 0.498 0.000
D00-D09 In situ neoplasms
0.501 0.498 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.501 0.498 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.501 0.498 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.501 0.498 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.501 0.498 0.000
C64-C68 Malignant neoplasms of urinary tract
0.501 0.498 0.000
C51-C58 Malignant neoplasms of female genital organs
0.501 0.498 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.501 0.498 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.501 0.498 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.501 0.498 0.000
C15-C26 Malignant neoplasms of digestive organs
0.501 0.498 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.501 0.498 0.000
I67.8 Other specified cerebrovascular diseases
0.501 0.499 0.000
F48 Other neurotic disorders
0.501 0.499 0.000
F45 Somatoform disorders
0.501 0.499 0.000
F44 Dissociative [conversion] disorders
0.501 0.499 0.000
F43 Reaction to severe stress, and adjustment disorders
0.501 0.499 0.000
F42 Obsessive-compulsive disorder
0.501 0.499 0.000
F40 Phobic anxiety disorders
0.501 0.499 0.000
E16 Other disorders of pancreatic internal secretion
0.500 0.500 0.000
E15 Nondiabetic hypoglycaemic coma
0.500 0.500 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.500 0.500 0.000
E34 Other endocrine disorders
0.500 0.500 0.000
E32 Diseases of thymus
0.500 0.500 0.000
E31 Polyglandular dysfunction
0.500 0.500 0.000
E30 Disorders of puberty, not elsewhere classified
0.500 0.500 0.000
E29 Testicular dysfunction
0.500 0.500 0.000
E28 Ovarian dysfunction
0.500 0.500 0.000
E27 Other disorders of adrenal gland
0.500 0.500 0.000
E26 Hyperaldosteronism
0.500 0.500 0.000
E25 Adrenogenital disorders
0.500 0.500 0.000
E24 Cushing's syndrome
0.500 0.500 0.000
E23 Hypofunction and other disorders of pituitary gland
0.500 0.500 0.000
E22 Hyperfunction of pituitary gland
0.500 0.500 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.500 0.500 0.000
E20 Hypoparathyroidism
0.500 0.500 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.500 0.500 0.000
E46 Unspecified protein-energy malnutrition
0.500 0.500 0.000
E45 Retarded development following protein-energy malnutrition
0.500 0.500 0.000
E43 Unspecified severe protein-energy malnutrition
0.500 0.500 0.000
E42 Marasmic kwashiorkor
0.500 0.500 0.000
E41 Nutritional marasmus
0.500 0.500 0.000
E40 Kwashiorkor
0.500 0.500 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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