TreeWAS – Variant ID: rs7042161

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Z00.0 General medical examination	0.065	0.935	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.000	0.982	0.018
F00.9 Dementia in Alzheimer's disease, unspecified	0.000	0.983	0.017
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.016	0.984	0.000
Z00.8 Other general examinations	0.013	0.986	0.000
M77.91 Enthesopathy, unspecified (Shoulder region)	0.012	0.988	0.000
Z00.4 General psychiatric examination, not elsewhere classified	0.012	0.988	0.000
Z00.3 Examination for adolescent development state	0.011	0.988	0.000
Z00.2 Examination for period of rapid growth in childhood	0.011	0.988	0.000
Z00.1 Routine child health examination	0.011	0.988	0.000
F00 Dementia in Alzheimer's disease	0.000	0.989	0.011
F00.1 Dementia in Alzheimer's disease with late onset	0.000	0.990	0.010
F00.0 Dementia in Alzheimer's disease with early onset	0.000	0.991	0.009
H81.0 Meniere's disease	0.009	0.991	0.000
S82.30 Fracture of lower end of tibia (closed)	0.000	0.992	0.008
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.000	0.992	0.008
H34.8 Other retinal vascular occlusions	0.000	0.992	0.008
Z00.6 Examination for normal comparison and control in clinical research programme	0.007	0.993	0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.000	0.993	0.007
J44 Other chronic obstructive pulmonary disease	0.000	0.994	0.006
M81.90 Osteoporosis, unspecified (Multiple sites)	0.000	0.994	0.006
H34.2 Other retinal artery occlusions	0.000	0.994	0.006
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.006	0.994	0.000
H34 Retinal vascular occlusions	0.000	0.994	0.006
E85.4 Organ-limited amyloidosis	0.006	0.994	0.000
E85.9 Amyloidosis, unspecified	0.005	0.994	0.000
E85 Amyloidosis	0.005	0.995	0.000
Z00.5 Examination of potential donor of organ and tissue	0.005	0.995	0.000
M77.9 Enthesopathy, unspecified	0.005	0.995	0.000
D22.5 Melanocytic naevi of trunk	0.005	0.995	0.000
E85.3 Secondary systemic amyloidosis	0.005	0.995	0.000
H34.9 Retinal vascular occlusion, unspecified	0.000	0.995	0.005
T93.2 Sequelae of other fractures of lower limb	0.005	0.995	0.000
H34.1 Central retinal artery occlusion	0.000	0.995	0.005
E85.8 Other amyloidosis	0.005	0.995	0.000
M81.9 Osteoporosis, unspecified	0.000	0.995	0.005
H34.0 Transient retinal artery occlusion	0.000	0.995	0.004
M77.95 Enthesopathy, unspecified (Pelvic region and thigh)	0.004	0.995	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.000	0.996	0.004
X41.9 Unspecified place	0.004	0.996	0.000
S82.3 Fracture of lower end of tibia	0.000	0.996	0.004
M77.93 Enthesopathy, unspecified (Forearm)	0.004	0.996	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.004	0.996	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.004	0.996	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.004	0.996	0.000
M77.99 Enthesopathy, unspecified (Site unspecified)	0.004	0.996	0.000
M77.98 Enthesopathy, unspecified (Other)	0.004	0.996	0.000
M77.90 Enthesopathy, unspecified (Multiple sites)	0.004	0.996	0.000
M77.97 Enthesopathy, unspecified (Ankle and foot)	0.004	0.996	0.000
M77.94 Enthesopathy, unspecified (Hand)	0.004	0.996	0.000
L57.0 Actinic keratosis	0.004	0.996	0.000
J32.2 Chronic ethmoidal sinusitis	0.004	0.996	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.000	0.996	0.004
M81.98 Osteoporosis, unspecified (Other)	0.000	0.996	0.004
M81.93 Osteoporosis, unspecified (Forearm)	0.000	0.996	0.004
R52.1 Chronic intractable pain	0.000	0.996	0.004
M77.92 Enthesopathy, unspecified (Upper arm)	0.004	0.996	0.000
S01.5 Open wound of lip and oral cavity	0.004	0.996	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.004	0.996	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.000	0.996	0.003
S82.31 Fracture of lower end of tibia (open)	0.000	0.996	0.004
T93.8 Sequelae of other specified injuries of lower limb	0.004	0.996	0.000
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.000	0.996	0.004
M81.91 Osteoporosis, unspecified (Shoulder region)	0.000	0.996	0.003
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.000	0.997	0.003
M77.96 Enthesopathy, unspecified (Lower leg)	0.003	0.997	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.000	0.997	0.003
T93.9 Sequelae of unspecified injury of lower limb	0.003	0.997	0.000
T93 Sequelae of injuries of lower limb	0.003	0.997	0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.000	0.997	0.003
J32.0 Chronic maxillary sinusitis	0.003	0.997	0.000
S72.30 Fracture of shaft of femur (closed)	0.003	0.997	0.000
S01.8 Open wound of other parts of head	0.003	0.997	0.000
T14.0 Superficial injury of unspecified body region	0.003	0.997	0.000
H61.8 Other specified disorders of external ear	0.000	0.997	0.003
S01 Open wound of head	0.003	0.997	0.000
J32 Chronic sinusitis	0.003	0.997	0.000
H61.2 Impacted cerumen	0.000	0.997	0.003
J32.4 Chronic pansinusitis	0.003	0.997	0.000
S01.0 Open wound of scalp	0.003	0.997	0.000
J32.8 Other chronic sinusitis	0.003	0.997	0.000
J44.8 Other specified chronic obstructive pulmonary disease	0.000	0.997	0.003
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.003	0.997	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.003	0.997	0.000
S01.3 Open wound of ear	0.003	0.997	0.000
H61.1 Non-infective disorders of pinna	0.000	0.997	0.003
S01.2 Open wound of nose	0.003	0.997	0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.002	0.997	0.000
S01.4 Open wound of cheek and temporomandibular area	0.002	0.997	0.000
S60.7 Multiple superficial injuries of wrist and hand	0.000	0.998	0.002
H61 Other disorders of external ear	0.000	0.998	0.002
Z40 Prophylactic surgery	0.002	0.998	0.000
F11.2 Dependence syndrome	0.000	0.998	0.002
T46.4 Angiotensin-converting-enzyme inhibitors	0.002	0.998	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.002	0.998	0.000
T93.1 Sequelae of fracture of femur	0.002	0.998	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
G82.1 Spastic paraplegia	0.002	0.998	0.000
S01.1 Open wound of eyelid and periocular area	0.002	0.998	0.000
Z52.4 Kidney donor	0.000	0.998	0.002
M81 Osteoporosis without pathological fracture	0.000	0.998	0.002
I67.8 Other specified cerebrovascular diseases	0.000	0.998	0.002
S01.7 Multiple open wounds of head	0.002	0.998	0.000
L90.0 Lichen sclerosus et atrophicus	0.002	0.998	0.000
G82.2 Paraplegia, unspecified	0.002	0.998	0.000
J32.3 Chronic sphenoidal sinusitis	0.002	0.998	0.000
T93.0 Sequelae of open wound of lower limb	0.002	0.998	0.000
S60.8 Other superficial injuries of wrist and hand	0.000	0.998	0.002
Z40.9 Prophylactic surgery, unspecified	0.002	0.998	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
R52.2 Other chronic pain	0.000	0.998	0.002
X41.2 School, other institution and public administrative area	0.002	0.998	0.000
J32.1 Chronic frontal sinusitis	0.002	0.998	0.000
I74.5 Embolism and thrombosis of iliac artery	0.002	0.998	0.000
R40.2 Coma, unspecified	0.000	0.998	0.002
X41.0 Home	0.002	0.998	0.000
X41.8 Other specified place	0.002	0.998	0.000
X41.7 Farm	0.002	0.998	0.000
X41.6 Industrial and construction area	0.002	0.998	0.000
X41.5 Trade and service area	0.002	0.998	0.000
X41.4 Street and highway	0.002	0.998	0.000
X41.3 Sports and athletics area	0.002	0.998	0.000
X41.1 Residential institution	0.002	0.998	0.000
M81.4 Drug-induced osteoporosis	0.000	0.998	0.002
X51.9 Unspecified place	0.000	0.998	0.002
Q51.3 Bicornate uterus	0.000	0.998	0.002
S60 Superficial injury of wrist and hand	0.000	0.998	0.002
M81.0 Postmenopausal osteoporosis	0.000	0.998	0.002
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.002	0.998	0.000
R52 Pain, not elsewhere classified	0.000	0.998	0.002
Q51.8 Other congenital malformations of uterus and cervix	0.000	0.998	0.002
S60.2 Contusion of other parts of wrist and hand	0.000	0.998	0.002
S60.0 Contusion of finger(s) without damage to nail	0.000	0.998	0.002
Q51 Congenital malformations of uterus and cervix	0.000	0.998	0.002
M80.9 Unspecified osteoporosis with pathological fracture	0.002	0.998	0.000
M81.8 Other osteoporosis	0.000	0.998	0.002
M81.6 Localised osteoporosis [Lequesne]	0.000	0.998	0.002
M81.5 Idiopathic osteoporosis	0.000	0.998	0.002
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.000	0.998	0.002
G82 Paraplegia and tetraplegia	0.002	0.998	0.000
M81.1 Postoophorectomy osteoporosis	0.000	0.998	0.002
H61.3 Acquired stenosis of external ear canal	0.000	0.998	0.002
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
M81.49 Drug-induced osteoporosis (Site unspecified)	0.000	0.998	0.002
K00.6 Disturbances in tooth eruption	0.000	0.998	0.002
Q51.2 Other doubling of uterus	0.000	0.998	0.002
S60.1 Contusion of finger(s) with damage to nail	0.000	0.998	0.002
T43.5 Other and unspecified antipsychotics and neuroleptics	0.002	0.998	0.000
M81.2 Osteoporosis of disuse	0.000	0.998	0.002
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.000	0.998	0.002
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.000	0.998	0.002
B35.1 Tinea unguium	0.002	0.998	0.000
H61.9 Disorder of external ear, unspecified	0.000	0.998	0.002
X51.8 Other specified place	0.000	0.998	0.002
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.002	0.998	0.000
X41.08 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, antiparkinsonism and psychotropic drugs, not elsewhere classified , Home ,While engaged in other specified activities	0.002	0.998	0.000
K56.7 Ileus, unspecified	0.000	0.998	0.002
M81.48 Drug-induced osteoporosis (Other)	0.000	0.998	0.002
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.000	0.998	0.002
M81.46 Drug-induced osteoporosis (Lower leg)	0.000	0.998	0.002
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.000	0.998	0.002
M81.44 Drug-induced osteoporosis (Hand)	0.000	0.998	0.002
M81.43 Drug-induced osteoporosis (Forearm)	0.000	0.998	0.002
M81.42 Drug-induced osteoporosis (Upper arm)	0.000	0.998	0.002
M81.41 Drug-induced osteoporosis (Shoulder region)	0.000	0.998	0.002
J37.0 Chronic laryngitis	0.002	0.998	0.000
Z40.8 Other prophylactic surgery	0.002	0.998	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.000	0.998	0.002
I05.9 Mitral valve disease, unspecified	0.000	0.998	0.002
M81.08 Postmenopausal osteoporosis (Other)	0.000	0.998	0.001
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.000	0.998	0.001
M81.06 Postmenopausal osteoporosis (Lower leg)	0.000	0.998	0.001
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.000	0.998	0.001
M81.04 Postmenopausal osteoporosis (Hand)	0.000	0.998	0.001
M81.03 Postmenopausal osteoporosis (Forearm)	0.000	0.998	0.001
M81.02 Postmenopausal osteoporosis (Upper arm)	0.000	0.998	0.001
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.000	0.998	0.001
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.000	0.998	0.001
F23.9 Acute and transient psychotic disorder, unspecified	0.002	0.998	0.000
G82.5 Tetraplegia, unspecified	0.002	0.998	0.000
N70.9 Salpingitis and oophoritis, unspecified	0.002	0.998	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.002	0.998	0.000
B02.2 Zoster with other nervous system involvement	0.000	0.998	0.002
G82.0 Flaccid paraplegia	0.002	0.998	0.000
D84.9 Immunodeficiency, unspecified	0.002	0.998	0.000
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.000	0.998	0.002
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.000	0.998	0.002
Q51.6 Embryonic cyst of cervix	0.000	0.998	0.002
Q51.5 Agenesis and aplasia of cervix	0.000	0.998	0.002
Q51.0 Agenesis and aplasia of uterus	0.000	0.998	0.002
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
M81.59 Idiopathic osteoporosis (Site unspecified)	0.000	0.998	0.001
M81.58 Idiopathic osteoporosis (Other)	0.000	0.998	0.001
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.000	0.998	0.001
M81.56 Idiopathic osteoporosis (Lower leg)	0.000	0.998	0.001
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.000	0.998	0.001
M81.54 Idiopathic osteoporosis (Hand)	0.000	0.998	0.001
M81.53 Idiopathic osteoporosis (Forearm)	0.000	0.998	0.001
M81.52 Idiopathic osteoporosis (Upper arm)	0.000	0.998	0.001
M81.51 Idiopathic osteoporosis (Shoulder region)	0.000	0.998	0.001
M81.50 Idiopathic osteoporosis (Multiple sites)	0.000	0.998	0.001
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.000	0.998	0.001
M81.68 Localized osteoporosis [Lequesne] (Other)	0.000	0.998	0.001
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.000	0.998	0.001
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.000	0.998	0.001
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.000	0.998	0.001
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.000	0.998	0.001
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.000	0.998	0.001
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.000	0.998	0.001
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.000	0.998	0.001
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.000	0.998	0.001
M81.89 Other osteoporosis (Site unspecified)	0.000	0.998	0.001
M81.88 Other osteoporosis (Other)	0.000	0.998	0.001
M81.87 Other osteoporosis (Ankle and foot)	0.000	0.998	0.001
M81.86 Other osteoporosis (Lower leg)	0.000	0.998	0.001
M81.85 Other osteoporosis (Pelvic region and thigh)	0.000	0.998	0.001
M81.84 Other osteoporosis (Hand)	0.000	0.998	0.001
M81.83 Other osteoporosis (Forearm)	0.000	0.998	0.001
M81.82 Other osteoporosis (Upper arm)	0.000	0.998	0.001
M81.81 Other osteoporosis (Shoulder region)	0.000	0.998	0.001
M81.80 Other osteoporosis (Multiple sites)	0.000	0.998	0.001
G82.3 Flaccid tetraplegia	0.002	0.998	0.000
H49.0 Third [oculomotor] nerve palsy	0.000	0.998	0.002
T14 Injury of unspecified body region	0.002	0.998	0.000
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.000	0.998	0.001
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.000	0.998	0.001
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.000	0.998	0.001
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.000	0.998	0.001
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.000	0.998	0.001
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.000	0.998	0.001
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.000	0.998	0.001
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.000	0.998	0.001
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.000	0.998	0.001
J33.0 Polyp of nasal cavity	0.002	0.998	0.000
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.000	0.998	0.001
M81.18 Postoophorectomy osteoporosis (Other)	0.000	0.998	0.001
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.000	0.998	0.001
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.000	0.998	0.001
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.000	0.998	0.001
M81.14 Postoophorectomy osteoporosis (Hand)	0.000	0.998	0.001
M81.13 Postoophorectomy osteoporosis (Forearm)	0.000	0.998	0.001
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.000	0.998	0.001
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.000	0.998	0.001
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.000	0.998	0.001
L43.9 Lichen planus, unspecified	0.000	0.998	0.002
T14.9 Injury, unspecified	0.002	0.998	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.002	0.998	0.000
F17.2 Dependence syndrome	0.000	0.998	0.002
F50.0 Anorexia nervosa	0.002	0.998	0.000
N85.9 Noninflammatory disorder of uterus, unspecified	0.000	0.998	0.002
H81 Disorders of vestibular function	0.002	0.998	0.000
X51 Travel and motion	0.000	0.998	0.002
Q54.9 Hypospadias, unspecified	0.000	0.998	0.002
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.000	0.998	0.001
M81.29 Osteoporosis of disuse (Site unspecified)	0.000	0.998	0.001
M81.28 Osteoporosis of disuse (Other)	0.000	0.998	0.001
M81.27 Osteoporosis of disuse (Ankle and foot)	0.000	0.998	0.001
M81.26 Osteoporosis of disuse (Lower leg)	0.000	0.998	0.001
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.000	0.998	0.001
M81.24 Osteoporosis of disuse (Hand)	0.000	0.998	0.001
M81.23 Osteoporosis of disuse (Forearm)	0.000	0.998	0.001
M81.22 Osteoporosis of disuse (Upper arm)	0.000	0.998	0.001
M81.21 Osteoporosis of disuse (Shoulder region)	0.000	0.998	0.001
D26.0 Cervix uteri	0.002	0.998	0.000
G82.4 Spastic tetraplegia	0.001	0.998	0.000
T14.4 Injury of nerve(s) of unspecified body region	0.001	0.998	0.000
Q55.6 Other congenital malformations of penis	0.000	0.998	0.001
Q54 Hypospadias	0.000	0.998	0.002
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.001	0.998	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.001	0.998	0.000
F11.3 Withdrawal state	0.000	0.998	0.001
S72.3 Fracture of shaft of femur	0.001	0.998	0.000
T14.3 Dislocation, sprain and strain of unspecified body region	0.001	0.998	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.001	0.998	0.000
M66.34 Spontaneous rupture of flexor tendons (Hand)	0.001	0.999	0.000
H81.8 Other disorders of vestibular function	0.001	0.999	0.000
Q51.4 Unicornate uterus	0.000	0.999	0.001
T14.2 Fracture of unspecified body region	0.001	0.999	0.000
T14.8 Other injuries of unspecified body region	0.001	0.999	0.000
T14.7 Crushing injury and traumatic amputation of unspecified body region	0.001	0.999	0.000
T14.5 Injury of blood vessel(s) of unspecified body region	0.001	0.999	0.000
T43.2 Other and unspecified antidepressants	0.001	0.999	0.000
Z34.0 Supervision of normal first pregnancy	0.001	0.999	0.000
A49.8 Other bacterial infections of unspecified site	0.001	0.999	0.000
Q54.1 Hypospadias, penile	0.000	0.999	0.001
R52.0 Acute pain	0.000	0.999	0.001
T79.3 Post-traumatic wound infection, not elsewhere classified	0.001	0.999	0.000
H61.0 Perichondritis of external ear	0.000	0.999	0.001
H81.4 Vertigo of central origin	0.001	0.999	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.001	0.999	0.000
T46.7 Peripheral vasodilators	0.001	0.999	0.000
M67.1 Other contracture of tendon (sheath)	0.000	0.999	0.001
T46.1 Calcium-channel blockers	0.001	0.999	0.000
X51.7 Farm	0.000	0.999	0.001
X51.6 Industrial and construction area	0.000	0.999	0.001
X51.5 Trade and service area	0.000	0.999	0.001
X51.4 Street and highway	0.000	0.999	0.001
X51.3 Sports and athletics area	0.000	0.999	0.001
X51.2 School, other institution and public administrative area	0.000	0.999	0.001
X51.1 Residential institution	0.000	0.999	0.001
X51.0 Home	0.000	0.999	0.001
M81.20 Osteoporosis of disuse (Multiple sites)	0.000	0.999	0.001
I22.8 Subsequent myocardial infarction of other sites	0.001	0.999	0.000
J05.1 Acute epiglottitis	0.000	0.999	0.001
Q53.1 Undescended testicle, unilateral	0.000	0.999	0.001
T46.5 Other antihypertensive drugs, not elsewhere classified	0.001	0.999	0.000
Q55 Other congenital malformations of male genital organs	0.000	0.999	0.001
M77.57 Other enthesopathy of foot-Ankle/Foot	0.001	0.999	0.000
G30.9 Alzheimer's disease, unspecified	0.000	0.999	0.001
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.999	0.001
O86.0 Infection of obstetric surgical wound	0.000	0.999	0.001
Q53 Undescended testicle	0.000	0.999	0.001
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.001	0.999	0.000
Q50-Q56 Congenital malformations of genital organs	0.000	0.999	0.001
F11 Mental and behavioural disorders due to use of opioids	0.000	0.999	0.001
L57 Skin changes due to chronic exposure to nonionising radiation	0.001	0.999	0.000
Q54.4 Congenital chordee	0.000	0.999	0.001
Q54.3 Hypospadias, perineal	0.000	0.999	0.001
Q54.2 Hypospadias, penoscrotal	0.000	0.999	0.001
T14.6 Injury of tendons and muscles of unspecified body region	0.001	0.999	0.000
T43.6 Psychostimulants with abuse potential	0.001	0.999	0.000
D10.0 Lip	0.001	0.999	0.000
H81.9 Disorder of vestibular function, unspecified	0.001	0.999	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.001	0.999	0.000
K04.4 Acute apical periodontitis of pulpal origin	0.001	0.999	0.000
Q53.2 Undescended testicle, bilateral	0.000	0.999	0.001
S46.2 Injury of muscle and tendon of other parts of biceps	0.001	0.999	0.000
Q52 Other congenital malformations of female genitalia	0.000	0.999	0.001
S82.40 Fracture of fibula alone (closed)	0.001	0.999	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.001	0.999	0.000
H81.3 Other peripheral vertigo	0.001	0.999	0.000
J03.9 Acute tonsillitis, unspecified	0.000	0.999	0.001
O86.1 Other infection of genital tract following delivery	0.000	0.999	0.001
Q54.8 Other hypospadias	0.000	0.999	0.001
Q55.2 Other congenital malformations of testis and scrotum	0.000	0.999	0.001
R52.9 Pain, unspecified	0.000	0.999	0.001
M66.31 Spontaneous rupture of flexor tendons (Shoulder region)	0.001	0.999	0.000
T14.21 Fracture of unspecified body region (open)	0.001	0.999	0.000
T14.20 Fracture of unspecified body region (closed)	0.001	0.999	0.000
M77.5 Other enthesopathy of foot	0.001	0.999	0.000
N18.4 Chronic kidney disease, stage 4	0.001	0.999	0.000
Q54.0 Hypospadias, balanic	0.000	0.999	0.001
T46.3 Coronary vasodilators, not elsewhere classified	0.001	0.999	0.000
Z83.3 Family history of diabetes mellitus	0.001	0.999	0.000
J10 Influenza due to identified influenza virus	0.000	0.999	0.001
S72.31 Fracture of shaft of femur (open)	0.001	0.999	0.000
C21.1 Anal canal	0.000	0.999	0.001
F02.8 Dementia in other specified diseases classified elsewhere	0.000	0.999	0.001
J18.0 Bronchopneumonia, unspecified	0.000	0.999	0.001
O86.8 Other specified puerperal infections	0.000	0.999	0.001
T79.6 Traumatic ischaemia of muscle	0.001	0.999	0.000
Z35.5 Supervision of elderly primigravida	0.000	0.999	0.001
M66.33 Spontaneous rupture of flexor tendons (Forearm)	0.001	0.999	0.000
D84.1 Defects in the complement system	0.001	0.999	0.000
F11.1 Harmful use	0.000	0.999	0.001
Q55.9 Congenital malformation of male genital organ, unspecified	0.000	0.999	0.001
Q55.8 Other specified congenital malformations of male genital organs	0.000	0.999	0.001
Q55.5 Congenital absence and aplasia of penis	0.000	0.999	0.001
Q55.3 Atresia of vas deferens	0.000	0.999	0.001
Q55.1 Hypoplasia of testis and scrotum	0.000	0.999	0.001
Q55.0 Absence and aplasia of testis	0.000	0.999	0.001
F50.2 Bulimia nervosa	0.001	0.999	0.000
H27.8 Other specified disorders of lens	0.001	0.999	0.000
H43.3 Other vitreous opacities	0.000	0.999	0.001
L57.3 Poikiloderma of Civatte	0.001	0.999	0.000
L57.2 Cutis rhomboidalis nuchae	0.001	0.999	0.000
L57.1 Actinic reticuloid	0.001	0.999	0.000
O86.2 Urinary tract infection following delivery	0.000	0.999	0.001
Q52.5 Fusion of labia	0.000	0.999	0.001
Q52.1 Doubling of vagina	0.000	0.999	0.001
Q53.0 Ectopic testis	0.000	0.999	0.001
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.000	0.999	0.001
T24.3 Burn of third degree of hip and lower limb, except ankle and foot	0.001	0.999	0.000
T43.9 Psychotropic drug, unspecified	0.001	0.999	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.001	0.999	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.000	0.999	0.001
F11.9 Unspecified mental and behavioural disorder	0.000	0.999	0.001
F11.8 Other mental and behavioural disorders	0.000	0.999	0.001
F11.7 Residual and late-onset psychotic disorder	0.000	0.999	0.001
F11.6 Amnesic syndrome	0.000	0.999	0.001
F11.5 Psychotic disorder	0.000	0.999	0.001
F11.4 Withdrawal state with delirium	0.000	0.999	0.001
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified	0.001	0.999	0.000
L57.5 Actinic granuloma	0.001	0.999	0.000
M75.2 Bicipital tendinitis	0.001	0.999	0.000
A86 Unspecified viral encephalitis	0.000	0.999	0.001
D84 Other immunodeficiencies	0.001	0.999	0.000
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease	0.000	0.999	0.001
F06.7 Mild cognitive disorder	0.000	0.999	0.001
H50.0 Convergent concomitant strabismus	0.000	0.999	0.001
Q52.9 Congenital malformation of female genitalia, unspecified	0.000	0.999	0.001
Q52.8 Other specified congenital malformations of female genitalia	0.000	0.999	0.001
Q52.7 Other congenital malformations of vulva	0.000	0.999	0.001
Q52.6 Congenital malformation of clitoris	0.000	0.999	0.001
Q52.3 Imperforate hymen	0.000	0.999	0.001
Q52.2 Congenital rectovaginal fistula	0.000	0.999	0.001
Q52.0 Congenital absence of vagina	0.000	0.999	0.001
T14.1 Open wound of unspecified body region	0.001	0.999	0.000
M77 Other enthesopathies	0.001	0.999	0.000
M77.59 Other enthesopathy of foot-Site unspec	0.001	0.999	0.000
M77.58 Other enthesopathy of foot-Other	0.001	0.999	0.000
M77.56 Other enthesopathy of foot-Lower Leg	0.001	0.999	0.000
M77.55 Other enthesopathy of foot-Pelvic/Thigh	0.001	0.999	0.000
M77.54 Other enthesopathy of foot-Hand	0.001	0.999	0.000
M77.53 Other enthesopathy of foot-Forearm	0.001	0.999	0.000
M77.52 Other enthesopathy of foot-Upper arm	0.001	0.999	0.000
M77.51 Other enthesopathy of foot-Shldr region	0.001	0.999	0.000
M77.50 Other enthesopathy of foot-Mult sites	0.001	0.999	0.000
J10.8 Influenza with other manifestations, influenza virus identified	0.000	0.999	0.001
K04.7 Periapical abscess without sinus	0.001	0.999	0.000
K13.6 Irritative hyperplasia of oral mucosa	0.000	0.999	0.001
S67.0 Crushing injury of thumb and other finger(s)	0.000	0.999	0.001
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.001	0.999	0.000
I85.9 Oesophageal varices without bleeding	0.000	0.999	0.001
M22.2 Patellofemoral disorders	0.001	0.999	0.000
Q52.4 Other congenital malformations of vagina	0.000	0.999	0.001
J39.8 Other specified diseases of upper respiratory tract	0.001	0.999	0.000
L57.4 Cutis laxa senilis	0.001	0.999	0.000
M66.3 Spontaneous rupture of flexor tendons	0.001	0.999	0.000
Q53.9 Undescended testicle, unspecified	0.000	0.999	0.001
Q56.4 Indeterminate sex, unspecified	0.000	0.999	0.001
Q56.3 Pseudohermaphroditism, unspecified	0.000	0.999	0.001
Q56.2 Female pseudohermaphroditism, not elsewhere classified	0.000	0.999	0.001
Q56.1 Male pseudohermaphroditism, not elsewhere classified	0.000	0.999	0.001
Q56.0 Hermaphroditism, not elsewhere classified	0.000	0.999	0.001
Z52.3 Bone marrow donor	0.000	0.999	0.001
O86 Other puerperal infections	0.000	0.999	0.001
M89.87 Other specified disorders of bone (Ankle and foot)	0.001	0.999	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.001	0.999	0.000
J69.0 Pneumonitis due to food and vomit	0.000	0.999	0.001
R22.1 Localised swelling, mass and lump, neck	0.001	0.999	0.000
S60.9 Superficial injury of wrist and hand, unspecified	0.000	0.999	0.001
T43.4 Butyrophenone and thioxanthene neuroleptics	0.001	0.999	0.000
D73.5 Infarction of spleen	0.001	0.999	0.000
G83.9 Paralytic syndrome, unspecified	0.001	0.999	0.000
M77.8 Other enthesopathies, not elsewhere classified	0.001	0.999	0.000
M77.3 Calcaneal spur	0.001	0.999	0.000
M77.2 Periarthritis of wrist	0.001	0.999	0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.000	0.999	0.001
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.001	0.999	0.000
X45.0 Home	0.001	0.999	0.000
Y89.9 Sequelae of unspecified external cause	0.001	0.999	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.000	0.999	0.001
F50 Eating disorders	0.001	0.999	0.000
D12.0 Caecum	0.000	0.999	0.001
F11.0 Acute intoxication	0.000	0.999	0.001
J32.9 Chronic sinusitis, unspecified	0.001	0.999	0.000
N99.0 Postprocedural renal failure	0.000	0.999	0.001
Z30.3 Menstrual extraction	0.000	0.999	0.001
F00-F09 Organic, including symptomatic, mental disorders	0.000	0.999	0.001
M66.39 Spontaneous rupture of flexor tendons (Site unspecified)	0.001	0.999	0.000
M66.38 Spontaneous rupture of flexor tendons (Other)	0.001	0.999	0.000
M66.37 Spontaneous rupture of flexor tendons (Ankle and foot)	0.001	0.999	0.000
M66.35 Spontaneous rupture of flexor tendons (Pelvic region and thigh)	0.001	0.999	0.000
M66.32 Spontaneous rupture of flexor tendons (Upper arm)	0.001	0.999	0.000
M66.30 Spontaneous rupture of flexor tendons (Multiple sites)	0.001	0.999	0.000
S42.40 Fracture of lower end of humerus (closed)	0.000	0.999	0.001
B02.3 Zoster ocular disease	0.000	0.999	0.001
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.001	0.999	0.000
O86.3 Other genito-urinary tract infections following delivery	0.000	0.999	0.001
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.000	0.999	0.001
M77.39 Calcaneal spur-Site unspec	0.001	0.999	0.000
M77.38 Calcaneal spur-Other	0.001	0.999	0.000
M77.36 Calcaneal spur-Lower Leg	0.001	0.999	0.000
M77.35 Calcaneal spur-Pelvic/Thigh	0.001	0.999	0.000
M77.34 Calcaneal spur-Hand	0.001	0.999	0.000
M77.33 Calcaneal spur-Forearm	0.001	0.999	0.000
M77.32 Calcaneal spur-Upper arm	0.001	0.999	0.000
M77.31 Calcaneal spur-Shldr region	0.001	0.999	0.000
M77.30 Calcaneal spur-Mult sites	0.001	0.999	0.000
C16.9 Stomach, unspecified	0.000	0.999	0.001
D84.8 Other specified immunodeficiencies	0.001	0.999	0.000
F50.9 Eating disorder, unspecified	0.001	0.999	0.000
T92.0 Sequelae of open wound of upper limb	0.001	0.999	0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.001	0.999	0.000
M77.29 Periarthritis of wrist-Site unspec	0.001	0.999	0.000
M77.28 Periarthritis of wrist-Other	0.001	0.999	0.000
M77.27 Periarthritis of wrist-Ankle/Foot	0.001	0.999	0.000
M77.26 Periarthritis of wrist-Lower Leg	0.001	0.999	0.000
M77.25 Periarthritis of wrist-Pelvic/Thigh	0.001	0.999	0.000
M77.24 Periarthritis of wrist-Hand	0.001	0.999	0.000
M77.23 Periarthritis of wrist-Forearm	0.001	0.999	0.000
M77.22 Periarthritis of wrist-Upper arm	0.001	0.999	0.000
M77.21 Periarthritis of wrist-Shldr region	0.001	0.999	0.000
M77.20 Periarthritis of wrist-Mult sites	0.001	0.999	0.000
M77.37 Calcaneal spur-Ankle/Foot	0.001	0.999	0.000
M77.89 Other enthesopathies, not elsewhere classified (Site unspecified)	0.001	0.999	0.000
M77.88 Other enthesopathies, not elsewhere classified (Other)	0.001	0.999	0.000
M77.87 Other enthesopathies, not elsewhere classified (Ankle and foot)	0.001	0.999	0.000
M77.86 Other enthesopathies, not elsewhere classified (Lower leg)	0.001	0.999	0.000
M77.85 Other enthesopathies, not elsewhere classified (Pelvic region and thigh)	0.001	0.999	0.000
M77.84 Other enthesopathies, not elsewhere classified (Hand)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations