TreeWAS – Variant ID: rs7069733

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
R15 Faecal incontinence	0.000	0.062	0.938
Z92.1 Personal history of long-term (current) use of anticoagulants	0.846	0.154	0.000
R13 Dysphagia	0.000	0.882	0.118
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.000	0.882	0.118
R14 Flatulence and related conditions	0.000	0.888	0.112
R12 Heartburn	0.000	0.936	0.064
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.000	0.940	0.060
R17 Unspecified jaundice	0.000	0.954	0.046
R16.2 Hepatomegaly with splenomegaly, not elsewhere classified	0.000	0.954	0.046
T78.3 Angioneurotic oedema	0.034	0.966	0.000
T78 Adverse effects, not elsewhere classified	0.033	0.967	0.000
R16.0 Hepatomegaly, not elsewhere classified	0.000	0.968	0.032
T78.0 Anaphylactic shock due to adverse food reaction	0.031	0.969	0.000
R19 Other symptoms and signs involving the digestive system and abdomen	0.000	0.970	0.030
T78.2 Anaphylactic shock, unspecified	0.030	0.970	0.000
R16.1 Splenomegaly, not elsewhere classified	0.000	0.970	0.030
T78.4 Allergy, unspecified	0.029	0.971	0.000
R18 Ascites	0.000	0.971	0.029
R19.5 Other fecal abnormalities	0.000	0.972	0.028
T78.8 Other adverse effects, not elsewhere classified	0.026	0.974	0.000
R10 Abdominal and pelvic pain	0.000	0.975	0.025
T78.9 Adverse effect, unspecified	0.024	0.976	0.000
R19.6 Halitosis	0.000	0.977	0.023
T78.1 Other adverse food reactions, not elsewhere classified	0.023	0.977	0.000
R19.3 Abdominal rigidity	0.000	0.978	0.022
R19.2 Visible peristalsis	0.000	0.978	0.022
R19.1 Abnormal bowel sounds	0.000	0.978	0.022
R10.1 Pain localised to upper abdomen	0.000	0.978	0.022
M81.99 Osteoporosis, unspecified (Site unspecified)	0.000	0.979	0.021
R10.0 Acute abdomen	0.000	0.981	0.019
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.000	0.983	0.017
Z92 Personal history of medical treatment	0.016	0.984	0.000
J98.4 Other disorders of lung	0.000	0.985	0.015
Z92.4 Personal history of major surgery, not elsewhere classified	0.013	0.987	0.000
Z92.9 Personal history of medical treatment, unspecified	0.011	0.989	0.000
Z92.5 Personal history of rehabilitation measures	0.011	0.989	0.000
M81.9 Osteoporosis, unspecified	0.000	0.989	0.011
M35.0 Sicca syndrome [Sjogren]	0.011	0.989	0.000
C50.8 Overlapping lesion of breast	0.000	0.989	0.011
Z92.0 Personal history of contraception	0.010	0.990	0.000
T66-T78 Other and unspecified effects of external causes	0.010	0.990	0.000
M81.98 Osteoporosis, unspecified (Other)	0.000	0.991	0.009
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.000	0.991	0.009
R10.2 Pelvic and perineal pain	0.000	0.991	0.009
M81.96 Osteoporosis, unspecified (Lower leg)	0.000	0.992	0.008
M81.94 Osteoporosis, unspecified (Hand)	0.000	0.992	0.008
M81.93 Osteoporosis, unspecified (Forearm)	0.000	0.992	0.008
M81.92 Osteoporosis, unspecified (Upper arm)	0.000	0.992	0.008
M81.91 Osteoporosis, unspecified (Shoulder region)	0.000	0.992	0.008
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.000	0.992	0.008
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.000	0.992	0.008
G40 Epilepsy	0.000	0.992	0.008
T66 Unspecified effects of radiation	0.007	0.992	0.000
T74 Maltreatment syndromes	0.007	0.993	0.000
T73 Effects of other deprivation	0.007	0.993	0.000
T70 Effects of air pressure and water pressure	0.007	0.993	0.000
T69 Other effects of reduced temperature	0.007	0.993	0.000
T67 Effects of heat and light	0.007	0.993	0.000
T71 Asphyxiation	0.007	0.993	0.000
Z92.8 Personal history of other medical treatment	0.007	0.993	0.000
T75 Effects of other external causes	0.007	0.993	0.000
M13.96 Arthritis, unspecified (Lower leg)	0.007	0.993	0.000
G40.8 Other epilepsy	0.000	0.993	0.006
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.000	0.994	0.006
I20.9 Angina pectoris, unspecified	0.000	0.994	0.006
I20.1 Angina pectoris with documented spasm	0.000	0.994	0.006
M81 Osteoporosis without pathological fracture	0.000	0.994	0.006
R19.4 Change in bowel habit	0.000	0.994	0.006
I20 Angina pectoris	0.000	0.994	0.006
G40.4 Other generalised epilepsy and epileptic syndromes	0.000	0.994	0.006
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.000	0.994	0.006
T68 Hypothermia	0.005	0.994	0.000
T67.9 Effects of heat and light, unspecified	0.005	0.994	0.000
T67.8 Other effects of heat and light	0.005	0.994	0.000
T67.7 Heat oedema	0.005	0.994	0.000
T67.6 Heat fatigue, transient	0.005	0.994	0.000
T67.5 Heat exhaustion, unspecified	0.005	0.994	0.000
T67.4 Heat exhaustion due to salt depletion	0.005	0.994	0.000
T67.3 Heat exhaustion, anhydrotic	0.005	0.994	0.000
T67.2 Heat cramp	0.005	0.994	0.000
T67.1 Heat syncope	0.005	0.994	0.000
T67.0 Heatstroke and sunstroke	0.005	0.994	0.000
T69.9 Effect of reduced temperature, unspecified	0.005	0.994	0.000
T69.8 Other specified effects of reduced temperature	0.005	0.994	0.000
T69.1 Chilblains	0.005	0.994	0.000
T69.0 Immersion hand and foot	0.005	0.994	0.000
T70.9 Effect of air pressure and water pressure, unspecified	0.005	0.994	0.000
T70.8 Other effects of air pressure and water pressure	0.005	0.994	0.000
T70.4 Effects of high-pressure fluids	0.005	0.994	0.000
T70.3 Caisson disease [decompression sickness]	0.005	0.994	0.000
T70.2 Other and unspecified effects of high altitude	0.005	0.994	0.000
T70.1 Sinus barotrauma	0.005	0.994	0.000
T70.0 Otitic barotrauma	0.005	0.994	0.000
T73.9 Effect of deprivation, unspecified	0.005	0.994	0.000
T73.8 Other effects of deprivation	0.005	0.994	0.000
T73.3 Exhaustion due to excessive exertion	0.005	0.994	0.000
T73.2 Exhaustion due to exposure	0.005	0.994	0.000
T73.1 Effects of thirst	0.005	0.994	0.000
T73.0 Effects of hunger	0.005	0.994	0.000
T74.9 Maltreatment syndrome, unspecified	0.005	0.994	0.000
T74.8 Other maltreatment syndromes	0.005	0.994	0.000
T74.3 Psychological abuse	0.005	0.994	0.000
T74.2 Sexual abuse	0.005	0.994	0.000
T74.1 Physical abuse	0.005	0.994	0.000
T74.0 Neglect or abandonment	0.005	0.994	0.000
I20.8 Other forms of angina pectoris	0.000	0.995	0.005
T75.8 Other specified effects of external causes	0.005	0.995	0.000
T75.3 Motion sickness	0.005	0.995	0.000
T75.2 Effects of vibration	0.005	0.995	0.000
T75.1 Drowning and nonfatal submersion	0.005	0.995	0.000
T75.0 Effects of lightning	0.005	0.995	0.000
R19.0 Intra-abdominal and pelvic swelling, mass and lump	0.000	0.995	0.005
I05.0 Mitral stenosis	0.005	0.995	0.000
M81.4 Drug-induced osteoporosis	0.000	0.995	0.005
G40.5 Special epileptic syndromes	0.000	0.995	0.005
T75.4 Effects of electric current	0.005	0.995	0.000
G40.7 Petit mal, unspecified, without grand mal seizures	0.000	0.995	0.004
M81.2 Osteoporosis of disuse	0.000	0.995	0.004
M81.8 Other osteoporosis	0.000	0.995	0.004
M81.6 Localised osteoporosis [Lequesne]	0.000	0.995	0.004
M81.5 Idiopathic osteoporosis	0.000	0.995	0.004
M81.3 Postsurgical malabsorption osteoporosis	0.000	0.995	0.004
M81.1 Postoophorectomy osteoporosis	0.000	0.995	0.004
M81.40 Drug-induced osteoporosis (Multiple sites)	0.000	0.996	0.004
M81.0 Postmenopausal osteoporosis	0.000	0.996	0.004
M81.90 Osteoporosis, unspecified (Multiple sites)	0.000	0.996	0.004
Y57.9 Drug or medicament, unspecified	0.004	0.996	0.000
I20.0 Unstable angina	0.000	0.996	0.004
I08.0 Disorders of both mitral and aortic valves	0.004	0.996	0.000
M81.48 Drug-induced osteoporosis (Other)	0.000	0.996	0.004
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.000	0.996	0.004
M81.46 Drug-induced osteoporosis (Lower leg)	0.000	0.996	0.004
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.000	0.996	0.004
M81.44 Drug-induced osteoporosis (Hand)	0.000	0.996	0.004
M81.43 Drug-induced osteoporosis (Forearm)	0.000	0.996	0.004
M81.42 Drug-induced osteoporosis (Upper arm)	0.000	0.996	0.004
M81.41 Drug-induced osteoporosis (Shoulder region)	0.000	0.996	0.004
M81.49 Drug-induced osteoporosis (Site unspecified)	0.000	0.996	0.004
G40.9 Epilepsy, unspecified	0.000	0.996	0.004
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.000	0.996	0.004
J98 Other respiratory disorders	0.000	0.996	0.004
Z92.6 Personal history of chemotherapy for neoplastic disease	0.004	0.996	0.000
M81.20 Osteoporosis of disuse (Multiple sites)	0.000	0.996	0.003
M81.29 Osteoporosis of disuse (Site unspecified)	0.000	0.996	0.003
M81.28 Osteoporosis of disuse (Other)	0.000	0.996	0.003
M81.27 Osteoporosis of disuse (Ankle and foot)	0.000	0.996	0.003
M81.26 Osteoporosis of disuse (Lower leg)	0.000	0.996	0.003
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.000	0.996	0.003
M81.24 Osteoporosis of disuse (Hand)	0.000	0.996	0.003
M81.23 Osteoporosis of disuse (Forearm)	0.000	0.996	0.003
M81.22 Osteoporosis of disuse (Upper arm)	0.000	0.996	0.003
M81.21 Osteoporosis of disuse (Shoulder region)	0.000	0.996	0.003
M22.2 Patellofemoral disorders	0.004	0.996	0.000
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.000	0.996	0.003
M81.18 Postoophorectomy osteoporosis (Other)	0.000	0.996	0.003
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.000	0.996	0.003
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.000	0.996	0.003
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.000	0.996	0.003
M81.14 Postoophorectomy osteoporosis (Hand)	0.000	0.996	0.003
M81.13 Postoophorectomy osteoporosis (Forearm)	0.000	0.996	0.003
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.000	0.996	0.003
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.000	0.996	0.003
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.000	0.996	0.003
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.000	0.996	0.003
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.000	0.996	0.003
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.000	0.996	0.003
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.000	0.996	0.003
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.000	0.996	0.003
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.000	0.996	0.003
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.000	0.996	0.003
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.000	0.996	0.003
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.000	0.996	0.003
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.000	0.996	0.003
M81.59 Idiopathic osteoporosis (Site unspecified)	0.000	0.996	0.003
M81.58 Idiopathic osteoporosis (Other)	0.000	0.996	0.003
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.000	0.996	0.003
M81.56 Idiopathic osteoporosis (Lower leg)	0.000	0.996	0.003
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.000	0.996	0.003
M81.54 Idiopathic osteoporosis (Hand)	0.000	0.996	0.003
M81.53 Idiopathic osteoporosis (Forearm)	0.000	0.996	0.003
M81.52 Idiopathic osteoporosis (Upper arm)	0.000	0.996	0.003
M81.51 Idiopathic osteoporosis (Shoulder region)	0.000	0.996	0.003
M81.50 Idiopathic osteoporosis (Multiple sites)	0.000	0.996	0.003
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.000	0.996	0.003
M81.68 Localized osteoporosis [Lequesne] (Other)	0.000	0.996	0.003
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.000	0.996	0.003
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.000	0.996	0.003
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.000	0.996	0.003
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.000	0.996	0.003
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.000	0.996	0.003
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.000	0.996	0.003
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.000	0.996	0.003
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.000	0.996	0.003
M81.89 Other osteoporosis (Site unspecified)	0.000	0.996	0.003
M81.88 Other osteoporosis (Other)	0.000	0.996	0.003
M81.87 Other osteoporosis (Ankle and foot)	0.000	0.996	0.003
M81.86 Other osteoporosis (Lower leg)	0.000	0.996	0.003
M81.85 Other osteoporosis (Pelvic region and thigh)	0.000	0.996	0.003
M81.84 Other osteoporosis (Hand)	0.000	0.996	0.003
M81.83 Other osteoporosis (Forearm)	0.000	0.996	0.003
M81.82 Other osteoporosis (Upper arm)	0.000	0.996	0.003
M81.81 Other osteoporosis (Shoulder region)	0.000	0.996	0.003
M81.80 Other osteoporosis (Multiple sites)	0.000	0.996	0.003
I05 Rheumatic mitral valve diseases	0.003	0.996	0.000
N71.9 Inflammatory disease of uterus, unspecified	0.003	0.997	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.000	0.997	0.003
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.003	0.997	0.000
M81.08 Postmenopausal osteoporosis (Other)	0.000	0.997	0.003
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.000	0.997	0.003
M81.06 Postmenopausal osteoporosis (Lower leg)	0.000	0.997	0.003
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.000	0.997	0.003
M81.04 Postmenopausal osteoporosis (Hand)	0.000	0.997	0.003
M81.03 Postmenopausal osteoporosis (Forearm)	0.000	0.997	0.003
M81.02 Postmenopausal osteoporosis (Upper arm)	0.000	0.997	0.003
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.000	0.997	0.003
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.000	0.997	0.003
E04.2 Non-toxic multinodular goitre	0.000	0.997	0.003
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.000	0.997	0.003
R11 Nausea and vomiting	0.000	0.997	0.003
I08 Multiple valve diseases	0.003	0.997	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.003	0.997	0.000
I05.9 Mitral valve disease, unspecified	0.003	0.997	0.000
J98.5 Diseases of mediastinum, not elsewhere classified	0.000	0.997	0.003
Z35.1 Supervision of pregnancy with history of abortive outcome	0.000	0.997	0.003
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.000	0.997	0.003
J98.3 Compensatory emphysema	0.000	0.997	0.003
J98.2 Interstitial emphysema	0.000	0.997	0.003
J98.0 Diseases of bronchus, not elsewhere classified	0.000	0.997	0.003
Y57 Other and unspecified drugs and medicaments	0.003	0.997	0.000
I05.8 Other mitral valve diseases	0.003	0.997	0.000
K57.1 Diverticular disease of small intestine without perforation or abscess	0.000	0.997	0.003
I08.2 Disorders of both aortic and tricuspid valves	0.003	0.997	0.000
Y57.5 X-ray contrast media	0.003	0.997	0.000
I05.1 Rheumatic mitral insufficiency	0.002	0.997	0.000
R19.8 Other specified symptoms and signs involving the digestive system and abdomen	0.000	0.997	0.003
I05-I09 Chronic rheumatic heart diseases	0.003	0.997	0.000
J98.6 Disorders of diaphragm	0.000	0.997	0.002
N80.0 Endometriosis of uterus	0.003	0.997	0.000
I08.9 Multiple valve disease, unspecified	0.002	0.997	0.000
J39.2 Other diseases of pharynx	0.000	0.997	0.003
J98.1 Pulmonary collapse	0.000	0.997	0.003
I21.4 Acute subendocardial myocardial infarction	0.000	0.998	0.002
J98.9 Respiratory disorder, unspecified	0.000	0.998	0.002
Y57.7 Vitamins, not elsewhere classified	0.002	0.998	0.000
Y57.6 Other diagnostic agents	0.002	0.998	0.000
Y57.4 Pharmaceutical excipients	0.002	0.998	0.000
Y57.3 Alcohol deterrents	0.002	0.998	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.002	0.998	0.000
Y57.1 Lipotropic drugs	0.002	0.998	0.000
Y57.0 Appetite depressants [anorectics]	0.002	0.998	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.002	0.998	0.000
I09 Other rheumatic heart diseases	0.002	0.998	0.000
I34.0 Mitral (valve) insufficiency	0.002	0.998	0.000
I05.2 Mitral stenosis with insufficiency	0.002	0.998	0.000
G62.8 Other specified polyneuropathies	0.000	0.998	0.002
J98.8 Other specified respiratory disorders	0.000	0.998	0.002
I08.8 Other multiple valve diseases	0.002	0.998	0.000
K74.0 Hepatic fibrosis	0.000	0.998	0.002
Y57.8 Other drugs and medicaments	0.002	0.998	0.000
D63.0 Anaemia in neoplastic disease	0.000	0.998	0.002
I09.9 Rheumatic heart disease, unspecified	0.002	0.998	0.000
I06 Rheumatic aortic valve diseases	0.002	0.998	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
D07.5 Prostate	0.002	0.998	0.000
N28.8 Other specified disorders of kidney and ureter	0.002	0.998	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.000	0.998	0.002
H74.4 Polyp of middle ear	0.002	0.998	0.000
M11.2 Other chondrocalcinosis	0.002	0.998	0.000
K07.3 Anomalies of tooth position	0.002	0.998	0.000
O02.1 Missed abortion	0.000	0.998	0.002
Y42.1 Thyroid hormones and substitutes	0.002	0.998	0.000
Z35 Supervision of high-risk pregnancy	0.000	0.998	0.002
H66.9 Otitis media, unspecified	0.000	0.998	0.002
I09.8 Other specified rheumatic heart diseases	0.002	0.998	0.000
I09.2 Chronic rheumatic pericarditis	0.002	0.998	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.002	0.998	0.000
I09.0 Rheumatic myocarditis	0.002	0.998	0.000
H26.2 Complicated cataract	0.002	0.998	0.000
L71.9 Rosacea, unspecified	0.000	0.998	0.002
S06.30 Focal brain injury (without open intracranial wound)	0.000	0.998	0.002
L57.0 Actinic keratosis	0.000	0.998	0.002
M17.5 Other secondary gonarthrosis	0.002	0.998	0.000
H43.8 Other disorders of vitreous body	0.002	0.998	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.002	0.998	0.000
I06.8 Other rheumatic aortic valve diseases	0.002	0.998	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.002	0.998	0.000
I06.1 Rheumatic aortic insufficiency	0.002	0.998	0.000
I06.0 Rheumatic aortic stenosis	0.002	0.998	0.000
M89.9 Disorder of bone, unspecified	0.000	0.998	0.002
N90.4 Leukoplakia of vulva	0.000	0.998	0.002
Z35.0 Supervision of pregnancy with history of infertility	0.000	0.998	0.002
K59.1 Functional diarrhoea	0.002	0.998	0.000
Y42.2 Antithyroid drugs	0.002	0.998	0.000
G62.9 Polyneuropathy, unspecified	0.000	0.998	0.002
O72.1 Other immediate postpartum haemorrhage	0.000	0.998	0.002
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.002	0.998	0.000
H26.4 After-cataract	0.002	0.998	0.000
Z35.9 Supervision of high-risk pregnancy, unspecified	0.000	0.998	0.002
N71 Inflammatory disease of uterus, except cervix	0.002	0.998	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.002	0.998	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.000	0.998	0.002
M11.29 Other chondrocalcinosis (Site unspecified)	0.002	0.998	0.000
M11.28 Other chondrocalcinosis (Other)	0.002	0.998	0.000
M11.27 Other chondrocalcinosis (Ankle and foot)	0.002	0.998	0.000
M11.25 Other chondrocalcinosis (Pelvic region and thigh)	0.002	0.998	0.000
M11.24 Other chondrocalcinosis (Hand)	0.002	0.998	0.000
M11.23 Other chondrocalcinosis (Forearm)	0.002	0.998	0.000
M11.22 Other chondrocalcinosis (Upper arm)	0.002	0.998	0.000
M11.21 Other chondrocalcinosis (Shoulder region)	0.002	0.998	0.000
M11.20 Other chondrocalcinosis (Multiple sites)	0.002	0.998	0.000
Y52 Agents primarily affecting the cardiovascular system	0.002	0.998	0.000
G50.0 Trigeminal neuralgia	0.002	0.998	0.000
Z35.5 Supervision of elderly primigravida	0.000	0.998	0.002
G62 Other polyneuropathies	0.000	0.998	0.002
O63.9 Long labour, unspecified	0.000	0.998	0.002
C83.0 Small cell (diffuse)	0.002	0.998	0.000
S67.0 Crushing injury of thumb and other finger(s)	0.002	0.998	0.000
Y54.5 Other diuretics	0.002	0.998	0.000
O02.0 Blighted ovum and nonhydatidiform mole	0.000	0.998	0.002
R10.3 Pain localised to other parts of lower abdomen	0.000	0.998	0.002
Z35.7 Supervision of high-risk pregnancy due to social problems	0.000	0.998	0.002
Z35.6 Supervision of very young primigravida	0.000	0.998	0.002
Z35.3 Supervision of pregnancy with history of insufficient antenatal care	0.000	0.998	0.002
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.002	0.998	0.000
E05.9 Thyrotoxicosis, unspecified	0.002	0.998	0.000
G60.0 Hereditary motor and sensory neuropathy	0.000	0.998	0.002
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.000	0.998	0.002
N71.1 Chronic inflammatory disease of uterus	0.002	0.998	0.000
Z35.8 Supervision of other high-risk pregnancies	0.000	0.998	0.002
Z35.4 Supervision of pregnancy with grand multiparity	0.000	0.998	0.002
Z92.3 Personal history of irradiation	0.002	0.998	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.002	0.998	0.000
S92.30 Fracture of metatarsal bone (closed)	0.000	0.998	0.002
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.001	0.998	0.000
Z97.8 Presence of other specified devices	0.000	0.998	0.002
I07 Rheumatic tricuspid valve diseases	0.001	0.998	0.000
M89.99 Disorder of bone, unspecified (Site unspecified)	0.000	0.998	0.001
M89.93 Disorder of bone, unspecified (Forearm)	0.000	0.998	0.001
M89.92 Disorder of bone, unspecified (Upper arm)	0.000	0.998	0.001
M89.91 Disorder of bone, unspecified (Shoulder region)	0.000	0.998	0.001
M89.90 Disorder of bone, unspecified (Multiple sites)	0.000	0.998	0.001
S06.3 Focal brain injury	0.000	0.998	0.002
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.001	0.998	0.000
M89.96 Disorder of bone, unspecified (Lower leg)	0.000	0.998	0.001
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.001	0.998	0.000
H25.9 Senile cataract, unspecified	0.002	0.998	0.000
J32.9 Chronic sinusitis, unspecified	0.002	0.998	0.000
Y42.9 Other and unspecified hormone antagonists	0.001	0.998	0.000
Y42.4 Oral contraceptives	0.001	0.998	0.000
N71.0 Acute inflammatory disease of uterus	0.001	0.998	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.001	0.998	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.001	0.998	0.000
Y52.7 Peripheral vasodilators	0.001	0.998	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.001	0.998	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.001	0.998	0.000
G62.2 Polyneuropathy due to other toxic agents	0.000	0.998	0.001
G62.1 Alcoholic polyneuropathy	0.000	0.998	0.001
Y52.1 Calcium-channel blockers	0.001	0.998	0.000
I50.1 Left ventricular failure	0.001	0.999	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.001	0.999	0.000
I72.8 Aneurysm of other specified arteries	0.001	0.999	0.000
Y54.8 Agents affecting uric acid metabolism	0.001	0.999	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.001	0.999	0.000
Y54.9 Mineral salts, not elsewhere classified	0.001	0.999	0.000
Y54.7 Agents affecting calcification	0.001	0.999	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.001	0.999	0.000
Y54.4 Loop [high-ceiling] diuretics	0.001	0.999	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.001	0.999	0.000
Y54.0 Mineralocorticoids	0.001	0.999	0.000
M89.98 Disorder of bone, unspecified (Other)	0.000	0.999	0.001
E05.0 Thyrotoxicosis with diffuse goitre	0.001	0.999	0.000
O02 Other abnormal products of conception	0.000	0.999	0.001
Y58 Bacterial vaccines	0.001	0.999	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.001	0.999	0.000
D07.4 Penis	0.001	0.999	0.000
G41.9 Status epilepticus, unspecified	0.000	0.999	0.001
M35 Other systemic involvement of connective tissue	0.001	0.999	0.000
S06.31 Focal brain injury (with open intracranial wound)	0.000	0.999	0.001
I07.9 Tricuspid valve disease, unspecified	0.001	0.999	0.000
I07.8 Other tricuspid valve diseases	0.001	0.999	0.000
I07.2 Tricuspid stenosis with insufficiency	0.001	0.999	0.000
I07.0 Tricuspid stenosis	0.001	0.999	0.000
N05.9 Unspecified	0.001	0.999	0.000
Y40.0 Penicillins	0.001	0.999	0.000
Y58.0 BCG vaccine	0.001	0.999	0.000
G60 Hereditary and idiopathic neuropathy	0.000	0.999	0.001
S06.40 Epidural haemorrhage (without open intracranial wound)	0.000	0.999	0.001
H16.9 Keratitis, unspecified	0.001	0.999	0.000
H16.1 Other superficial keratitis without conjunctivitis	0.001	0.999	0.000
Y42.7 Androgens and anabolic congeners	0.001	0.999	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.001	0.999	0.000
E06.3 Autoimmune thyroiditis	0.000	0.999	0.001
Y46.7 Anti-Parkinsonism drugs	0.001	0.999	0.000
D07.2 Vagina	0.001	0.999	0.000
F10.2 Dependence syndrome	0.000	0.999	0.001
H26.0 Infantile, juvenile and presenile cataract	0.001	0.999	0.000
H40.8 Other glaucoma	0.001	0.999	0.000
N05.2 Diffuse membranous glomerulonephritis	0.001	0.999	0.000
G60.8 Other hereditary and idiopathic neuropathies	0.000	0.999	0.001
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.001	0.999	0.000
R79.0 Abnormal level of blood mineral	0.000	0.999	0.001
S06.4 Epidural haemorrhage	0.000	0.999	0.001
U80.1 Methicillin resistant agent	0.001	0.999	0.000
Y46.4 Iminostilbenes	0.001	0.999	0.000
B00.1 Herpesviral vesicular dermatitis	0.001	0.999	0.000
C45.0 Mesothelioma of pleura	0.001	0.999	0.000
E05.8 Other thyrotoxicosis	0.001	0.999	0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified	0.001	0.999	0.000
M35.2 Behcet's disease	0.001	0.999	0.000
W21.9 Unspecified place	0.001	0.999	0.000
D07 Carcinoma in situ of other and unspecified genital organs	0.001	0.999	0.000
Y59 Other and unspecified vaccines and biological substances	0.001	0.999	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.001	0.999	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.001	0.999	0.000
Y48 Anaesthetics and therapeutic gases	0.001	0.999	0.000
Y46.8 Antispasticity drugs	0.001	0.999	0.000
Y46.6 Other and unspecified antiepileptics	0.001	0.999	0.000
Y46.5 Valproic acid	0.001	0.999	0.000
Y46.3 Deoxybarbiturates	0.001	0.999	0.000
Y46.1 Oxazolidinediones	0.001	0.999	0.000
Y46.0 Succinimides	0.001	0.999	0.000
C18.0 Caecum	0.000	0.999	0.001
K74.5 Biliary cirrhosis, unspecified	0.000	0.999	0.001
M35.9 Systemic involvement of connective tissue, unspecified	0.001	0.999	0.000
M35.8 Other specified systemic involvement of connective tissue	0.001	0.999	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.001	0.999	0.000
M35.5 Multifocal fibrosclerosis	0.001	0.999	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.001	0.999	0.000
N99.4 Postprocedural pelvic peritoneal adhesions	0.000	0.999	0.001
O02.9 Abnormal product of conception, unspecified	0.000	0.999	0.001
O02.8 Other specified abnormal products of conception	0.000	0.999	0.001
R09.0 Asphyxia	0.000	0.999	0.001
Y46.2 Hydantoin derivatives	0.001	0.999	0.000
Y49.5 Other antipsychotics and neuroleptics	0.001	0.999	0.000
Y58.9 Other and unspecified bacterial vaccines	0.001	0.999	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.001	0.999	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.001	0.999	0.000
Y58.5 Diphtheria vaccine	0.001	0.999	0.000
Y58.4 Tetanus vaccine	0.001	0.999	0.000
Y58.3 Plague vaccine	0.001	0.999	0.000
Y58.2 Cholera vaccine	0.001	0.999	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.001	0.999	0.000
S06 Intracranial injury	0.000	0.999	0.001
S12.10 Fracture of second cervical vertebra (closed)	0.000	0.999	0.001
G60.9 Hereditary and idiopathic neuropathy, unspecified	0.000	0.999	0.001
G60.3 Idiopathic progressive neuropathy	0.000	0.999	0.001
G60.2 Neuropathy in association with hereditary ataxia	0.000	0.999	0.001
G60.1 Refsum's disease	0.000	0.999	0.001
H16.3 Interstitial and deep keratitis	0.001	0.999	0.000
N99.8 Other postprocedural disorders of genito-urinary system	0.000	0.999	0.001
O82.1 Delivery by emergency Caesarean section	0.000	0.999	0.001
Y49.2 Other and unspecified antidepressants	0.001	0.999	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.000	0.999	0.001
J92.0 Pleural plaque with presence of asbestos	0.001	0.999	0.000
Y49.9 Psychotropic drug, unspecified	0.001	0.999	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.001	0.999	0.000
Y49.7 Psychostimulants with abuse potential	0.001	0.999	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.001	0.999	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.001	0.999	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.001	0.999	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.001	0.999	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.001	0.999	0.000
H26 Other cataract	0.001	0.999	0.000
K74 Fibrosis and cirrhosis of liver	0.000	0.999	0.001
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.999	0.001
G61.0 Guillain-Barre syndrome	0.000	0.999	0.001
K13.0 Diseases of lips	0.000	0.999	0.001
Y49.0 Tricyclic and tetracyclic antidepressants	0.001	0.999	0.000
E46 Unspecified protein-energy malnutrition	0.000	0.999	0.001
Y47 Sedatives, hypnotics and antianxiety drugs	0.001	0.999	0.000
S06.41 Epidural haemorrhage (with open intracranial wound)	0.000	0.999	0.001
D07.6 Other and unspecified male genital organs	0.001	0.999	0.000
D07.3 Other and unspecified female genital organs	0.001	0.999	0.000
D07.0 Endometrium	0.001	0.999	0.000
G62.0 Drug-induced polyneuropathy	0.000	0.999	0.001
Y48.5 Therapeutic gases	0.001	0.999	0.000
Y48.1 Parenteral anaesthetics	0.001	0.999	0.000
Y48.0 Inhaled anaesthetics	0.001	0.999	0.000
Y50.9 Central nervous system stimulant, unspecified	0.001	0.999	0.000
Y50.8 Other central nervous system stimulants	0.001	0.999	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.001	0.999	0.000
Y50.1 Opioid receptor antagonists	0.001	0.999	0.000
Y50.0 Analeptics	0.001	0.999	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.001	0.999	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.001	0.999	0.000
Y55.5 Anticommon cold drugs	0.001	0.999	0.000
Y55.4 Expectorants	0.001	0.999	0.000
Y55.3 Antitussives	0.001	0.999	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.001	0.999	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.001	0.999	0.000
Y55.0 Oxytocic drugs	0.001	0.999	0.000
Y59.9 Vaccine or biological substance, unspecified	0.001	0.999	0.000
Y59.8 Other specified vaccines and biological substances	0.001	0.999	0.000
Y59.3 Immunoglobulin	0.001	0.999	0.000
Y59.2 Protozoal vaccines	0.001	0.999	0.000
Y59.1 Rickettsial vaccines	0.001	0.999	0.000
Y59.0 Viral vaccines	0.001	0.999	0.000
I21 Acute myocardial infarction	0.000	0.999	0.001
C22.0 Liver cell carcinoma	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations