TreeWAS – Variant ID: rs7078439

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H20.9 Iridocyclitis, unspecified	0.059	0.941	0.000
H20 Iridocyclitis	0.054	0.946	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.047	0.953	0.000
H18 Other disorders of cornea	0.046	0.954	0.000
H18.8 Other specified disorders of cornea	0.043	0.957	0.000
H20.1 Chronic iridocyclitis	0.043	0.957	0.000
H20.8 Other iridocyclitis	0.041	0.959	0.000
H18.5 Hereditary corneal dystrophies	0.041	0.959	0.000
H15 Disorders of sclera	0.040	0.960	0.000
H18.6 Keratoconus	0.039	0.961	0.000
H20.2 Lens-induced iridocyclitis	0.039	0.961	0.000
H20.0 Acute and subacute iridocyclitis	0.038	0.962	0.000
H16 Keratitis	0.037	0.963	0.000
H17 Corneal scars and opacities	0.035	0.965	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.033	0.966	0.000
H18.7 Other corneal deformities	0.033	0.967	0.000
H18.3 Changes in corneal membranes	0.033	0.967	0.000
H15.0 Scleritis	0.033	0.967	0.000
H18.0 Corneal pigmentations and deposits	0.032	0.968	0.000
H18.2 Other corneal oedema	0.032	0.968	0.000
H15.8 Other disorders of sclera	0.031	0.969	0.000
H21 Other disorders of iris and ciliary body	0.030	0.970	0.000
H15.1 Episcleritis	0.030	0.970	0.000
H18.1 Bullous keratopathy	0.029	0.970	0.000
H15.9 Disorder of sclera, unspecified	0.029	0.970	0.000
H16.0 Corneal ulcer	0.029	0.971	0.000
H16.3 Interstitial and deep keratitis	0.029	0.971	0.000
H18.9 Disorder of cornea, unspecified	0.029	0.971	0.000
H16.9 Keratitis, unspecified	0.029	0.971	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.029	0.971	0.000
H16.8 Other keratitis	0.029	0.971	0.000
H16.2 Keratoconjunctivitis	0.028	0.972	0.000
H18.4 Corneal degeneration	0.028	0.972	0.000
H16.4 Corneal neovascularisation	0.027	0.973	0.000
H17.8 Other corneal scars and opacities	0.027	0.973	0.000
I12.9 Hypertensive renal disease without renal failure	0.000	0.974	0.026
H17.9 Corneal scar and opacity, unspecified	0.026	0.974	0.000
H17.1 Other central corneal opacity	0.025	0.974	0.000
H17.0 Adherent leukoma	0.025	0.974	0.000
I12.0 Hypertensive renal disease with renal failure	0.000	0.975	0.025
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere	0.024	0.976	0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere	0.024	0.976	0.000
H22.1 Iridocyclitis in other diseases classified elsewhere	0.024	0.976	0.000
I12 Hypertensive renal disease	0.000	0.976	0.024
H21.2 Degeneration of iris and ciliary body	0.024	0.976	0.000
H21.5 Other adhesions and disruptions of iris and ciliary body	0.023	0.977	0.000
H21.9 Disorder of iris and ciliary body, unspecified	0.023	0.977	0.000
H21.4 Pupillary membranes	0.023	0.977	0.000
H21.0 Hyphaema	0.023	0.977	0.000
H21.3 Cyst of iris, ciliary body and anterior chamber	0.022	0.978	0.000
N64.8 Other specified disorders of breast	0.000	0.979	0.021
H19.1 Herpesviral keratitis and keratoconjunctivitis	0.021	0.979	0.000
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere	0.021	0.979	0.000
H19.0 Scleritis and episcleritis in diseases classified elsewhere	0.021	0.979	0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.019	0.981	0.000
H21.8 Other specified disorders of iris and ciliary body	0.019	0.981	0.000
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere	0.018	0.982	0.000
H16.1 Other superficial keratitis without conjunctivitis	0.017	0.983	0.001
N64 Other disorders of breast	0.000	0.984	0.016
N64.1 Fat necrosis of breast	0.000	0.985	0.015
N64.9 Disorder of breast, unspecified	0.000	0.985	0.015
T17.9 Foreign body in respiratory tract, part unspecified	0.015	0.985	0.000
T17 Foreign body in respiratory tract	0.013	0.987	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.013	0.987	0.001
N64.5 Other signs and symptoms in breast	0.000	0.988	0.012
T18.1 Foreign body in oesophagus	0.012	0.988	0.000
T18 Foreign body in alimentary tract	0.012	0.988	0.000
E66.8 Other obesity	0.012	0.988	0.000
N64.0 Fissure and fistula of nipple	0.000	0.988	0.012
N64.2 Atrophy of breast	0.000	0.988	0.012
S91.3 Open wound of other parts of foot	0.000	0.989	0.011
N64.3 Galactorrhoea not associated with childbirth	0.000	0.989	0.011
T17.8 Foreign body in other and multiple parts of respiratory tract	0.011	0.989	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.011	0.989	0.000
T17.2 Foreign body in pharynx	0.010	0.990	0.000
T17.5 Foreign body in bronchus	0.010	0.990	0.000
T18.9 Foreign body in alimentary tract, part unspecified	0.010	0.990	0.000
T18.3 Foreign body in small intestine	0.010	0.990	0.000
T17.4 Foreign body in trachea	0.010	0.990	0.000
T17.1 Foreign body in nostril	0.010	0.990	0.000
T17.0 Foreign body in nasal sinus	0.010	0.990	0.000
T17.3 Foreign body in larynx	0.010	0.990	0.000
T18.2 Foreign body in stomach	0.010	0.990	0.000
K07.3 Anomalies of tooth position	0.009	0.990	0.000
T18.0 Foreign body in mouth	0.009	0.991	0.000
T18.5 Foreign body in anus and rectum	0.009	0.991	0.000
T18.8 Foreign body in other and multiple parts of alimentary tract	0.009	0.991	0.000
T18.4 Foreign body in colon	0.009	0.991	0.000
Z97.8 Presence of other specified devices	0.009	0.991	0.000
O46.9 Antepartum haemorrhage, unspecified	0.009	0.991	0.000
N64.4 Mastodynia	0.000	0.991	0.009
C16.9 Stomach, unspecified	0.000	0.991	0.009
T19 Foreign body in genito-urinary tract	0.008	0.992	0.000
T16 Foreign body in ear	0.008	0.992	0.000
E66 Obesity	0.008	0.992	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.000	0.993	0.007
S91 Open wound of ankle and foot	0.000	0.993	0.007
T19.2 Foreign body in vulva and vagina	0.007	0.993	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.007	0.993	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.000	0.993	0.007
E66.0 Obesity due to excess calories	0.007	0.993	0.000
T15 Foreign body on external eye	0.006	0.993	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.000	0.993	0.007
T19.9 Foreign body in genito-urinary tract, part unspecified	0.006	0.994	0.000
T19.8 Foreign body in other and multiple parts of genito-urinary tract	0.006	0.994	0.000
T19.3 Foreign body in uterus [any part]	0.006	0.994	0.000
T19.0 Foreign body in urethra	0.006	0.994	0.000
K81.0 Acute cholecystitis	0.000	0.994	0.006
R41.2 Retrograde amnesia	0.006	0.994	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.000	0.994	0.006
E66.1 Drug-induced obesity	0.006	0.994	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.000	0.994	0.006
T19.1 Foreign body in bladder	0.005	0.994	0.000
S91.2 Open wound of toe(s) with damage to nail	0.000	0.994	0.005
S91.1 Open wound of toe(s) without damage to nail	0.000	0.994	0.006
S91.7 Multiple open wounds of ankle and foot	0.000	0.995	0.005
S91.0 Open wound of ankle	0.000	0.995	0.005
T15.9 Foreign body on external eye, unspecified	0.005	0.995	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.000	0.995	0.005
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.000	0.995	0.005
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.000	0.995	0.005
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.000	0.995	0.005
T15.8 Foreign body in other and multiple parts of external eye	0.005	0.995	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.000	0.995	0.005
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.000	0.995	0.005
I27.0 Primary pulmonary hypertension	0.005	0.995	0.000
T15.0 Foreign body in cornea	0.004	0.995	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.000	0.995	0.005
I27 Other pulmonary heart diseases	0.004	0.996	0.000
J69.0 Pneumonitis due to food and vomit	0.000	0.996	0.004
I27.2 Other secondary pulmonary hypertension	0.004	0.996	0.000
M84 Disorders of continuity of bone	0.000	0.996	0.004
J60-J70 Lung diseases due to external agents	0.000	0.996	0.004
J69 Pneumonitis due to solids and liquids	0.000	0.996	0.004
I27.9 Pulmonary heart disease, unspecified	0.004	0.996	0.000
D39.1 Ovary	0.000	0.996	0.004
T15.1 Foreign body in conjunctival sac	0.003	0.996	0.001
C16.6 Greater curvature of stomach, unspecified	0.000	0.996	0.004
M84.0 Malunion of fracture	0.000	0.996	0.004
J67 Hypersensitivity pneumonitis due to organic dust	0.000	0.996	0.004
O46 Antepartum haemorrhage, not elsewhere classified	0.004	0.996	0.000
C16 Malignant neoplasm of stomach	0.000	0.996	0.004
M84.03 Malunion of fracture (Forearm)	0.000	0.996	0.004
H52.2 Astigmatism	0.004	0.996	0.000
S93.0 Dislocation of ankle joint	0.000	0.996	0.004
H52.3 Anisometropia and aniseikonia	0.004	0.996	0.000
I27.8 Other specified pulmonary heart diseases	0.004	0.996	0.000
J70 Respiratory conditions due to other external agents	0.000	0.996	0.004
M34.9 Systemic sclerosis, unspecified	0.000	0.996	0.003
I27.1 Kyphoscoliotic heart disease	0.003	0.997	0.000
H90.5 Sensorineural hearing loss, unspecified	0.003	0.997	0.000
J67.9 Hypersensitivity pneumonitis due to unspecified organic dust	0.000	0.997	0.003
M84.2 Delayed union of fracture	0.000	0.997	0.003
S90-S99 Injuries to the ankle and foot	0.000	0.997	0.003
M84.02 Malunion of fracture (Upper arm)	0.000	0.997	0.003
A41.5 Septicaemia due to other Gram-negative organisms	0.000	0.997	0.003
M84.9 Disorder of continuity of bone, unspecified	0.000	0.997	0.003
M84.3 Stress fracture, not elsewhere classified	0.000	0.997	0.003
M84.07 Malunion of fracture (Ankle and foot)	0.000	0.997	0.003
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.997	0.003
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.997	0.003
J60 Coalworker's pneumoconiosis	0.000	0.997	0.003
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.000	0.997	0.003
I10-I15 Hypertensive diseases	0.000	0.997	0.003
S92.30 Fracture of metatarsal bone (closed)	0.000	0.997	0.003
T92.1 Sequelae of fracture of arm	0.000	0.997	0.003
M84.04 Malunion of fracture (Hand)	0.000	0.997	0.003
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours	0.000	0.997	0.003
J66 Airway disease due to specific organic dust	0.000	0.997	0.003
J63 Pneumoconiosis due to other inorganic dusts	0.000	0.997	0.003
J65 Pneumoconiosis associated with tuberculosis	0.000	0.997	0.003
J69.1 Pneumonitis due to oils and essences	0.000	0.997	0.003
M84.8 Other disorders of continuity of bone	0.000	0.997	0.003
J70.0 Acute pulmonary manifestations due to radiation	0.000	0.997	0.003
C16.8 Overlapping lesion of stomach	0.000	0.997	0.003
J70.4 Drug-induced interstitial lung disorder, unspecified	0.000	0.997	0.003
J67.2 Bird fancier's lung	0.000	0.997	0.003
J64 Unspecified pneumoconiosis	0.000	0.997	0.003
J62 Pneumoconiosis due to dust containing silica	0.000	0.997	0.003
C16.1 Fundus of stomach	0.000	0.997	0.003
C16.5 Lesser curvature of stomach, unspecified	0.000	0.997	0.003
M84.09 Malunion of fracture (Site unspecified)	0.000	0.997	0.003
M84.00 Malunion of fracture (Multiple sites)	0.000	0.997	0.003
J67.7 Air-conditioner and humidifier lung	0.000	0.997	0.003
J67.6 Maple-bark-stripper's lung	0.000	0.997	0.003
J67.5 Mushroom-worker's lung	0.000	0.997	0.003
J67.4 Maltworker's lung	0.000	0.997	0.003
J67.3 Suberosis	0.000	0.997	0.003
J67.1 Bagassosis	0.000	0.997	0.003
J67.0 Farmer's lung	0.000	0.997	0.003
M34.8 Other forms of systemic sclerosis	0.000	0.997	0.003
O46.0 Antepartum haemorrhage with coagulation defect	0.003	0.997	0.000
H52 Disorders of refraction and accommodation	0.003	0.997	0.000
C43.7 Malignant melanoma of lower limb, including hip	0.000	0.997	0.003
J39.8 Other specified diseases of upper respiratory tract	0.003	0.997	0.000
J67.8 Hypersensitivity pneumonitis due to other organic dusts	0.000	0.997	0.003
M80 Osteoporosis with pathological fracture	0.000	0.997	0.003
M84.08 Malunion of fracture (Other)	0.000	0.997	0.003
M84.21 Delayed union of fracture (Shoulder region)	0.000	0.997	0.003
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.000	0.997	0.003
J70.9 Respiratory conditions due to unspecified external agent	0.000	0.997	0.003
J70.8 Respiratory conditions due to other specified external agents	0.000	0.997	0.003
J70.3 Chronic drug-induced interstitial lung disorders	0.000	0.997	0.003
J70.2 Acute drug-induced interstitial lung disorders	0.000	0.997	0.003
O46.8 Other antepartum haemorrhage	0.003	0.997	0.000
S92.3 Fracture of metatarsal bone	0.000	0.997	0.003
L51.1 Bullous erythema multiforme	0.000	0.997	0.003
J69.8 Pneumonitis due to other solids and liquids	0.000	0.997	0.003
J70.1 Chronic and other pulmonary manifestations due to radiation	0.000	0.997	0.003
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.000	0.997	0.003
S93.3 Dislocation of other and unspecified parts of foot	0.000	0.997	0.003
S97 Crushing injury of ankle and foot	0.000	0.997	0.003
M84.29 Delayed union of fracture (Site unspecified)	0.000	0.997	0.003
M84.28 Delayed union of fracture (Other)	0.000	0.997	0.003
M84.27 Delayed union of fracture (Ankle and foot)	0.000	0.997	0.003
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.000	0.997	0.003
M84.24 Delayed union of fracture (Hand)	0.000	0.997	0.003
M84.23 Delayed union of fracture (Forearm)	0.000	0.997	0.003
M84.22 Delayed union of fracture (Upper arm)	0.000	0.997	0.003
M84.20 Delayed union of fracture (Multiple sites)	0.000	0.997	0.003
I13 Hypertensive heart and renal disease	0.000	0.997	0.003
M34 Systemic sclerosis	0.000	0.997	0.003
E23.7 Disorder of pituitary gland, unspecified	0.000	0.997	0.003
S95 Injury of blood vessels at ankle and foot level	0.000	0.997	0.003
S94 Injury of nerves at ankle and foot level	0.000	0.997	0.003
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.000	0.997	0.003
M80.8 Other osteoporosis with pathological fracture	0.000	0.997	0.003
S98 Traumatic amputation of ankle and foot	0.000	0.997	0.003
M80-M85 Disorders of bone density and structure	0.000	0.997	0.003
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.000	0.997	0.003
Q24.8 Other specified congenital malformations of heart	0.000	0.997	0.003
S96 Injury of muscle and tendon at ankle and foot level	0.000	0.997	0.003
M84.26 Delayed union of fracture (Lower leg)	0.000	0.997	0.002
Y79.2 Prosthetic and other implants, materials and accessory devices	0.003	0.997	0.000
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.000	0.997	0.002
M84.38 Stress fracture, not elsewhere classified (Other)	0.000	0.997	0.002
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.000	0.997	0.002
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.000	0.997	0.002
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.000	0.997	0.002
M84.34 Stress fracture, not elsewhere classified (Hand)	0.000	0.997	0.002
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.000	0.997	0.002
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.000	0.997	0.002
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.000	0.997	0.002
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.000	0.997	0.002
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.000	0.997	0.002
M84.98 Disorder of continuity of bone, unspecified (Other)	0.000	0.997	0.002
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.000	0.997	0.002
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.000	0.997	0.002
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.000	0.997	0.002
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.000	0.997	0.002
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.000	0.997	0.002
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.000	0.997	0.002
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.000	0.997	0.002
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.000	0.997	0.002
G44.2 Tension-type headache	0.000	0.997	0.003
H52.0 Hypermetropia	0.003	0.997	0.000
M34.1 CR(E)ST syndrome	0.000	0.997	0.003
S93.6 Sprain and strain of other and unspecified parts of foot	0.000	0.997	0.002
C16.3 Pyloric antrum	0.000	0.997	0.002
S93.4 Sprain and strain of ankle	0.000	0.997	0.002
S93.5 Sprain and strain of toe(s)	0.000	0.997	0.002
E23.2 Diabetes insipidus	0.000	0.997	0.003
M80.88 Other osteoporosis with pathological fracture (Other)	0.000	0.997	0.002
J63.8 Pneumoconiosis due to other specified inorganic dusts	0.000	0.997	0.002
J63.5 Stannosis	0.000	0.997	0.002
J63.4 Siderosis	0.000	0.997	0.002
J63.3 Graphite fibrosis (of lung)	0.000	0.997	0.002
J63.2 Berylliosis	0.000	0.997	0.002
J63.1 Bauxite fibrosis (of lung)	0.000	0.997	0.002
J63.0 Aluminosis (of lung)	0.000	0.997	0.002
J66.8 Airway disease due to other specific organic dusts	0.000	0.997	0.002
J66.2 Cannabinosis	0.000	0.997	0.002
J66.1 Flax-dresser's disease	0.000	0.997	0.002
J66.0 Byssinosis	0.000	0.997	0.002
J68.9 Unspecified respiratory condition due to chemicals, gases, fumes and vapours	0.000	0.997	0.002
J68.8 Other respiratory conditions due to chemicals, gases, fumes and vapours	0.000	0.997	0.002
J68.4 Chronic respiratory conditions due to chemicals, gases, fumes and vapours	0.000	0.997	0.002
J68.3 Other acute and subacute respiratory conditions due to chemicals, gases, fumes and vapours	0.000	0.997	0.002
J68.2 Upper respiratory inflammation due to chemicals, gases, fumes and vapours, not elsewhere classified	0.000	0.997	0.002
J68.1 Acute pulmonary oedema due to chemicals, gases, fumes and vapours	0.000	0.997	0.002
J68.0 Bronchitis and pneumonitis due to chemicals, gases, fumes and vapours	0.000	0.997	0.002
S92 Fracture of foot, except ankle	0.000	0.997	0.003
M84.89 Other disorders of continuity of bone (Site unspecified)	0.000	0.997	0.002
M84.88 Other disorders of continuity of bone (Other)	0.000	0.997	0.002
M84.86 Other disorders of continuity of bone (Lower leg)	0.000	0.997	0.002
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.000	0.997	0.002
M84.84 Other disorders of continuity of bone (Hand)	0.000	0.997	0.002
M84.82 Other disorders of continuity of bone (Upper arm)	0.000	0.997	0.002
M84.81 Other disorders of continuity of bone (Shoulder region)	0.000	0.997	0.002
M84.80 Other disorders of continuity of bone (Multiple sites)	0.000	0.997	0.002
C16.4 Pylorus	0.000	0.997	0.002
I15 Secondary hypertension	0.000	0.997	0.002
H52.4 Presbyopia	0.002	0.997	0.000
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.000	0.997	0.002
M80.9 Unspecified osteoporosis with pathological fracture	0.000	0.997	0.002
M84.05 Malunion of fracture (Pelvic region and thigh)	0.000	0.997	0.002
H52.7 Disorder of refraction, unspecified	0.002	0.997	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.997	0.002
I15.1 Hypertension secondary to other renal disorders	0.000	0.997	0.002
S93.2 Rupture of ligaments at ankle and foot level	0.000	0.997	0.002
S99 Other and unspecified injuries of ankle and foot	0.000	0.997	0.002
M84.06 Malunion of fracture (Lower leg)	0.000	0.998	0.002
I47.2 Ventricular tachycardia	0.000	0.998	0.002
J62.0 Pneumoconiosis due to talc dust	0.000	0.998	0.002
C16.2 Body of stomach	0.000	0.998	0.002
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
M84.83 Other disorders of continuity of bone (Forearm)	0.000	0.998	0.002
M80.0 Postmenopausal osteoporosis with pathological fracture	0.000	0.998	0.002
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.002	0.998	0.000
E66.9 Obesity, unspecified	0.002	0.998	0.000
H52.6 Other disorders of refraction	0.002	0.998	0.000
H52.5 Disorders of accommodation	0.002	0.998	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.000	0.998	0.002
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.000	0.998	0.002
M80.2 Osteoporosis of disuse with pathological fracture	0.000	0.998	0.002
S92.31 Fracture of metatarsal bone (open)	0.000	0.998	0.002
J62.8 Pneumoconiosis due to other dust containing silica	0.000	0.998	0.002
M85.0 Fibrous dysplasia (monostotic)	0.000	0.998	0.002
S97.1 Crushing injury of toe(s)	0.000	0.998	0.002
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.000	0.998	0.002
S90 Superficial injury of ankle and foot	0.000	0.998	0.002
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.002
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.000	0.998	0.002
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.002
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.002
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.002
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.000	0.998	0.002
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.002
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.002
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.002
M80.81 Other osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.002
S97.0 Crushing injury of ankle	0.000	0.998	0.002
T80.1 Vascular complications following infusion, transfusion and therapeutic injection	0.000	0.998	0.002
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.998	0.002
E23 Hypofunction and other disorders of pituitary gland	0.000	0.998	0.002
M34.2 Systemic sclerosis induced by drugs and chemicals	0.000	0.998	0.002
S94.9 Injury of unspecified nerve at ankle and foot level	0.000	0.998	0.002
S94.8 Injury of other nerves at ankle and foot level	0.000	0.998	0.002
S94.7 Injury of multiple nerves at ankle and foot level	0.000	0.998	0.002
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.000	0.998	0.002
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.000	0.998	0.002
S94.1 Injury of medial plantar nerve	0.000	0.998	0.002
S94.0 Injury of lateral plantar nerve	0.000	0.998	0.002
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.000	0.998	0.002
S95.8 Injury of other blood vessels at ankle and foot level	0.000	0.998	0.002
S95.7 Injury of multiple blood vessels at ankle and foot level	0.000	0.998	0.002
S95.2 Injury of dorsal vein of foot	0.000	0.998	0.002
S95.1 Injury of plantar artery of foot	0.000	0.998	0.002
S95.0 Injury of dorsal artery of foot	0.000	0.998	0.002
M83 Adult osteomalacia	0.000	0.998	0.002
M80.89 Other osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.002
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.002
M80.86 Other osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.002
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.002
M80.84 Other osteoporosis with pathological fracture (Hand)	0.000	0.998	0.002
M80.83 Other osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.002
M80.82 Other osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.002
M80.80 Other osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
M84.01 Malunion of fracture (Shoulder region)	0.000	0.998	0.002
S92.9 Fracture of foot, unspecified	0.000	0.998	0.002
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.998	0.002
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.000	0.998	0.002
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.000	0.998	0.002
S97.8 Crushing injury of other parts of ankle and foot	0.000	0.998	0.002
S98.4 Traumatic amputation of foot, level unspecified	0.000	0.998	0.002
S98.3 Traumatic amputation of other parts of foot	0.000	0.998	0.002
S98.2 Traumatic amputation of two or more toes	0.000	0.998	0.002
S98.0 Traumatic amputation of foot at ankle level	0.000	0.998	0.002
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.000	0.998	0.002
M25.76 Osteophyte (Lower leg)	0.002	0.998	0.000
S98.1 Traumatic amputation of one toe	0.000	0.998	0.002
M82 Osteoporosis in diseases classified elsewhere	0.000	0.998	0.002
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.000	0.998	0.002
S93.40 Sprain of unspecified ligament of ankle	0.000	0.998	0.002
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.000	0.998	0.002
R63.8 Other symptoms and signs concerning food and fluid intake	0.000	0.998	0.002
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.998	0.002
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.002	0.998	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.000	0.998	0.002
I15.2 Hypertension secondary to endocrine disorders	0.000	0.998	0.002
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene	0.002	0.998	0.000
M84.4 Pathological fracture, not elsewhere classified	0.000	0.998	0.002
S67.0 Crushing injury of thumb and other finger(s)	0.002	0.998	0.000
S92.1 Fracture of talus	0.000	0.998	0.002
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.002
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.002
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.000	0.998	0.002
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.002
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.002
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.002
E65-E68 Obesity and other hyperalimentation	0.002	0.998	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.002
M80.5 Idiopathic osteoporosis with pathological fracture	0.000	0.998	0.002
S90.1 Contusion of toe(s) without damage to nail	0.000	0.998	0.002
S99.7 Multiple injuries of ankle and foot	0.000	0.998	0.002
I11 Hypertensive heart disease	0.000	0.998	0.002
M34.0 Progressive systemic sclerosis	0.000	0.998	0.002
S92.7 Multiple fractures of foot	0.000	0.998	0.002
S96.8 Injury of other muscles and tendons at ankle and foot level	0.000	0.998	0.002
M85 Other disorders of bone density and structure	0.000	0.998	0.002
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.002
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.000	0.998	0.002
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.002
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.002
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.002
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.000	0.998	0.002
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.002
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.002
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.002
S90.0 Contusion of ankle	0.000	0.998	0.002
S92.2 Fracture of other tarsal bone(s)	0.000	0.998	0.002
M81.20 Osteoporosis of disuse (Multiple sites)	0.000	0.998	0.002
S92.90 Fracture of foot, unspecified (closed)	0.000	0.998	0.002
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.000	0.998	0.002
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.000	0.998	0.002
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.000	0.998	0.002
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.000	0.998	0.002
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.002
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.000	0.998	0.002
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.000	0.998	0.002
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.000	0.998	0.002
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.000	0.998	0.002
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.000	0.998	0.002
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.002
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.000	0.998	0.002
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.002
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.002
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.002
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.000	0.998	0.002
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.002
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.002
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.002
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.002
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.000	0.998	0.002
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.002
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.002
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.002
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)	0.000	0.998	0.002
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.002
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.002
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.002
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
C16.0 Cardia	0.000	0.998	0.002
I15.0 Renovascular hypertension	0.000	0.998	0.002
M83.8 Other adult osteomalacia	0.000	0.998	0.002
M83.3 Adult osteomalacia due to malnutrition	0.000	0.998	0.002
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)	0.000	0.998	0.002
M85.08 Fibrous dysplasia (monostotic) (Other)	0.000	0.998	0.002
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)	0.000	0.998	0.002
M85.06 Fibrous dysplasia (monostotic) (Lower leg)	0.000	0.998	0.002
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)	0.000	0.998	0.002
M85.04 Fibrous dysplasia (monostotic) (Hand)	0.000	0.998	0.002
M85.03 Fibrous dysplasia (monostotic) (Forearm)	0.000	0.998	0.002
M85.02 Fibrous dysplasia (monostotic) (Upper arm)	0.000	0.998	0.002
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)	0.000	0.998	0.002
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.002	0.998	0.000
M81.2 Osteoporosis of disuse	0.000	0.998	0.002
S92.5 Fracture of other toe	0.000	0.998	0.002
S93.1 Dislocation of toe(s)	0.000	0.998	0.002
S99.8 Other specified injuries of ankle and foot	0.000	0.998	0.002
Q61.2 Polycystic kidney, adult type	0.002	0.998	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.000	0.998	0.002
S90.2 Contusion of toe(s) with damage to nail	0.000	0.998	0.002
S99.9 Unspecified injury of ankle and foot	0.000	0.998	0.002
M81 Osteoporosis without pathological fracture	0.000	0.998	0.002
E23.6 Other disorders of pituitary gland	0.000	0.998	0.002
T80.2 Infections following infusion, transfusion and therapeutic injection	0.000	0.998	0.002
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.998	0.002
E23.1 Drug-induced hypopituitarism	0.000	0.998	0.002
I15.9 Seconday hypertension, unspecified	0.000	0.998	0.002
I15.8 Other secondary hypertension	0.000	0.998	0.002
S92.91 Fracture of foot, unspecified (open)	0.000	0.998	0.002
M81.4 Drug-induced osteoporosis	0.000	0.998	0.002
M83.9 Adult osteomalacia, unspecified	0.000	0.998	0.002
M83.5 Other drug-induced osteomalacia in adults	0.000	0.998	0.002
M83.4 Aluminum bone disease	0.000	0.998	0.002
M83.2 Adult osteomalacia due to malabsorption	0.000	0.998	0.002
M83.0 Puerperal osteomalacia	0.000	0.998	0.002
N90.4 Leukoplakia of vulva	0.002	0.998	0.000
S90.3 Contusion of other and unspecified parts of foot	0.000	0.998	0.002
I28 Other diseases of pulmonary vessels	0.002	0.998	0.000
M82.8 Osteoporosis in other diseases classified elsewhere	0.000	0.998	0.002
M82.0 Osteoporosis in multiple myelomatosis	0.000	0.998	0.002
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.000	0.998	0.002
Y52.3 Coronary vasodilators, not elsewhere classified	0.000	0.998	0.002
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.000	0.998	0.002
T80 Complications following infusion, transfusion and therapeutic injection	0.000	0.998	0.002
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.000	0.998	0.001
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.000	0.998	0.001
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.000	0.998	0.001
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.000	0.998	0.001
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.000	0.998	0.001
S92.11 Fracture of talus (open)	0.000	0.998	0.002
M83.30 Adult osteomalacia due to malnutrition (Multiple sites)	0.000	0.998	0.002
M82.1 Osteoporosis in endocrine disorders	0.000	0.998	0.002
N05.9 Unspecified	0.002	0.998	0.000
E67 Other hyperalimentation	0.002	0.998	0.000
E68 Sequelae of hyperalimentation	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations