TreeWAS – Variant ID: rs707891

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E83.1 Disorders of iron metabolism	0.000	0.000	1.000
I10 Essential (primary) hypertension	0.000	0.012	0.988
E83 Disorders of mineral metabolism	0.000	0.347	0.653
E83.3 Disorders of phosphorus metabolism	0.000	0.486	0.514
E83.5 Disorders of calcium metabolism	0.000	0.507	0.493
E83.4 Disorders of magnesium metabolism	0.000	0.511	0.489
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.532	0.468
E83.8 Other disorders of mineral metabolism	0.000	0.532	0.468
E83.2 Disorders of zinc metabolism	0.000	0.532	0.468
E83.0 Disorders of copper metabolism	0.000	0.532	0.468
K75 Other inflammatory liver diseases	0.000	0.688	0.312
K70-K77 Diseases of liver	0.000	0.691	0.309
K70 Alcoholic liver disease	0.000	0.695	0.305
K75.4 Autoimmune hepatitis	0.000	0.703	0.297
K75.9 Inflammatory liver disease, unspecified	0.000	0.710	0.290
K70.9 Alcoholic liver disease, unspecified	0.000	0.719	0.281
K70.4 Alcoholic hepatic failure	0.000	0.729	0.271
K74 Fibrosis and cirrhosis of liver	0.000	0.731	0.269
K75.8 Other specified inflammatory liver diseases	0.000	0.737	0.262
I10-I15 Hypertensive diseases	0.000	0.743	0.257
K75.0 Abscess of liver	0.000	0.746	0.254
K70.3 Alcoholic cirrhosis of liver	0.000	0.747	0.253
K73 Chronic hepatitis, not elsewhere classified	0.000	0.753	0.247
E80.4 Gilbert's syndrome	0.000	0.757	0.243
K72 Hepatic failure, not elsewhere classified	0.000	0.758	0.241
K76 Other diseases of liver	0.000	0.760	0.240
K74.6 Other and unspecified cirrhosis of liver	0.000	0.761	0.239
K70.0 Alcoholic fatty liver	0.000	0.765	0.235
K76.9 Liver disease, unspecified	0.000	0.767	0.233
K74.0 Hepatic fibrosis	0.000	0.768	0.232
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.769	0.231
K70.1 Alcoholic hepatitis	0.000	0.772	0.228
K75.3 Granulomatous hepatitis, not elsewhere classified	0.000	0.776	0.224
K75.2 Nonspecific reactive hepatitis	0.000	0.776	0.224
K75.1 Phlebitis of portal vein	0.000	0.776	0.224
K70.2 Alcoholic fibrosis and sclerosis of liver	0.000	0.776	0.224
E70-E90 Metabolic disorders	0.000	0.777	0.223
K77 Liver disorders in diseases classified elsewhere	0.000	0.778	0.221
K71 Toxic liver disease	0.000	0.778	0.221
K73.2 Chronic active hepatitis, not elsewhere classified	0.000	0.793	0.207
K72.0 Acute and subacute hepatic failure	0.000	0.795	0.205
K76.6 Portal hypertension	0.000	0.803	0.197
K74.4 Secondary biliary cirrhosis	0.000	0.807	0.193
K74.2 Hepatic fibrosis with hepatic sclerosis	0.000	0.807	0.193
K74.1 Hepatic sclerosis	0.000	0.807	0.193
I11 Hypertensive heart disease	0.000	0.808	0.192
I13 Hypertensive heart and renal disease	0.000	0.815	0.184
E73 Lactose intolerance	0.000	0.818	0.182
K73.8 Other chronic hepatitis, not elsewhere classified	0.000	0.823	0.177
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.000	0.823	0.177
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.000	0.823	0.177
K72.1 Chronic hepatic failure	0.000	0.827	0.173
K76.5 Hepatic veno-occlusive disease	0.000	0.827	0.172
K76.4 Peliosis hepatis	0.000	0.827	0.172
K76.3 Infarction of liver	0.000	0.827	0.172
K76.2 Central haemorrhagic necrosis of liver	0.000	0.827	0.172
E80.6 Other disorders of bilirubin metabolism	0.000	0.830	0.170
K74.3 Primary biliary cirrhosis	0.000	0.831	0.169
K73.9 Chronic hepatitis, unspecified	0.000	0.831	0.169
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.834	0.166
E80.5 Crigler-Najjar syndrome	0.000	0.834	0.166
E80.3 Defects of catalase and peroxydase	0.000	0.834	0.166
E80.2 Other porphyria	0.000	0.834	0.166
E80.1 Porphyria cutanea tarda	0.000	0.834	0.166
E80.0 Hereditary erythropoietic porphyria	0.000	0.834	0.166
E74 Other disorders of carbohydrate metabolism	0.000	0.838	0.162
E84 Cystic fibrosis	0.000	0.840	0.160
E77 Disorders of glycoprotein metabolism	0.000	0.840	0.160
E76 Disorders of glycosaminoglycan metabolism	0.000	0.840	0.160
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.840	0.160
E72 Other disorders of amino-acid metabolism	0.000	0.840	0.160
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.840	0.160
E70 Disorders of aromatic amino-acid metabolism	0.000	0.840	0.160
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.840	0.160
K71.9 Toxic liver disease, unspecified	0.000	0.841	0.159
K71.8 Toxic liver disease with other disorders of liver	0.000	0.841	0.159
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.000	0.841	0.159
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.000	0.841	0.159
K71.5 Toxic liver disease with chronic active hepatitis	0.000	0.841	0.159
K71.4 Toxic liver disease with chronic lobular hepatitis	0.000	0.841	0.159
K71.3 Toxic liver disease with chronic persistent hepatitis	0.000	0.841	0.159
K71.2 Toxic liver disease with acute hepatitis	0.000	0.841	0.159
K71.1 Toxic liver disease with hepatic necrosis	0.000	0.841	0.159
K71.0 Toxic liver disease with cholestasis	0.000	0.841	0.159
K77.8 Liver disorders in other diseases classified elsewhere	0.000	0.841	0.159
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.000	0.841	0.159
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.841	0.159
I12 Hypertensive renal disease	0.000	0.842	0.158
E79 Disorders of purine and pyrimidine metabolism	0.000	0.842	0.158
K74.5 Biliary cirrhosis, unspecified	0.000	0.845	0.155
E73.9 Lactose intolerance, unspecified	0.000	0.848	0.152
K76.7 Hepatorenal syndrome	0.000	0.848	0.152
K72.9 Hepatic failure, unspecified	0.000	0.848	0.152
K76.1 Chronic passive congestion of liver	0.000	0.851	0.149
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.867	0.132
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.867	0.132
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.867	0.132
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.867	0.132
I12.9 Hypertensive renal disease without renal failure	0.000	0.869	0.131
E73.8 Other lactose intolerance	0.000	0.869	0.130
E73.1 Secondary lactase deficiency	0.000	0.869	0.130
E73.0 Congenital lactase deficiency	0.000	0.869	0.130
I15 Secondary hypertension	0.000	0.876	0.124
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.881	0.119
K76.0 Fatty (change of) liver, not elsewhere classified	0.000	0.883	0.117
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.883	0.116
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.883	0.116
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.883	0.116
E74.2 Disorders of galactose metabolism	0.000	0.883	0.116
E74.1 Disorders of fructose metabolism	0.000	0.883	0.116
E74.0 Glycogen storage disease	0.000	0.883	0.116
E88 Other metabolic disorders	0.000	0.885	0.115
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.885	0.115
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.885	0.115
E70.3 Albinism	0.000	0.885	0.115
E70.2 Disorders of tyrosine metabolism	0.000	0.885	0.115
E70.1 Other hyperphenylalaninaemias	0.000	0.885	0.115
E70.0 Classical phenylketonuria	0.000	0.885	0.115
E71.3 Disorders of fatty-acid metabolism	0.000	0.885	0.115
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.885	0.115
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.885	0.115
E71.0 Maple-syrup-urine disease	0.000	0.885	0.115
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.885	0.115
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.885	0.115
E72.5 Disorders of glycine metabolism	0.000	0.885	0.115
E72.4 Disorders of ornithine metabolism	0.000	0.885	0.115
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.885	0.115
E72.2 Disorders of urea cycle metabolism	0.000	0.885	0.115
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.885	0.115
E72.0 Disorders of amino-acid transport	0.000	0.885	0.115
E75.6 Lipid storage disorder, unspecified	0.000	0.885	0.115
E75.5 Other lipid storage disorders	0.000	0.885	0.115
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.885	0.115
E75.3 Sphingolipidosis, unspecified	0.000	0.885	0.115
E75.2 Other sphingolipidosis	0.000	0.885	0.115
E75.1 Other gangliosidosis	0.000	0.885	0.115
E75.0 GM2 gangliosidosis	0.000	0.885	0.115
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.885	0.115
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.885	0.115
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.885	0.115
E76.2 Other mucopolysaccharidoses	0.000	0.885	0.115
E76.1 Mucopolysaccharidosis, type II	0.000	0.885	0.115
E76.0 Mucopolysaccharidosis, type I	0.000	0.885	0.115
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.885	0.115
E77.8 Other disorders of glycoprotein metabolism	0.000	0.885	0.115
E77.1 Defects in glycoprotein degradation	0.000	0.885	0.115
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.885	0.115
E84.9 Cystic fibrosis, unspecified	0.000	0.885	0.115
E84.8 Cystic fibrosis with other manifestations	0.000	0.885	0.115
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.885	0.115
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.885	0.115
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.886	0.114
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.886	0.113
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.886	0.113
E79.1 Lesch-Nyhan syndrome	0.000	0.886	0.113
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.888	0.112
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.891	0.109
E89.3 Postprocedural hypopituitarism	0.000	0.904	0.096
I15.8 Other secondary hypertension	0.000	0.911	0.089
I15.2 Hypertension secondary to endocrine disorders	0.000	0.911	0.089
I15.0 Renovascular hypertension	0.000	0.911	0.089
E85 Amyloidosis	0.001	0.917	0.082
E88.8 Other specified metabolic disorders	0.000	0.917	0.083
E88.3 Tumour lysis syndrome	0.000	0.917	0.083
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.918	0.082
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.921	0.079
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.921	0.079
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.921	0.079
E89.5 Postprocedural testicular hypofunction	0.000	0.921	0.079
E88.2 Lipomatosis, not elsewhere classified	0.000	0.922	0.078
E89.4 Postprocedural ovarian failure	0.000	0.923	0.077
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.930	0.070
E88.9 Metabolic disorder, unspecified	0.000	0.930	0.069
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.931	0.069
E89.1 Postprocedural hypoinsulinaemia	0.000	0.931	0.068
I15.9 Seconday hypertension, unspecified	0.001	0.932	0.067
I15.1 Hypertension secondary to other renal disorders	0.001	0.935	0.065
E89.2 Postprocedural hypoparathyroidism	0.000	0.938	0.062
E85.8 Other amyloidosis	0.001	0.940	0.059
E85.2 Heredofamilial amyloidosis, unspecified	0.001	0.940	0.059
E85.1 Neuropathic heredofamilial amyloidosis	0.001	0.940	0.059
E85.0 Nonneuropathic heredofamilial amyloidosis	0.001	0.940	0.059
O03 Spontaneous abortion	0.060	0.940	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.940	0.060
O03.9 Complete or unspecified, without complication	0.059	0.941	0.000
O70 Perineal laceration during delivery	0.059	0.941	0.000
O70.1 Second degree perineal laceration during delivery	0.058	0.942	0.000
K76.8 Other specified diseases of liver	0.000	0.943	0.057
O03.4 Incomplete, without complication	0.056	0.944	0.000
E78.1 Pure hyperglyceridaemia	0.000	0.944	0.056
O70.0 First degree perineal laceration during delivery	0.056	0.944	0.000
O60-O75 Complications of labour and delivery	0.053	0.947	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.053	0.947	0.000
O00-O08 Pregnancy with abortive outcome	0.053	0.947	0.000
E85.3 Secondary systemic amyloidosis	0.001	0.948	0.051
E78.5 Hyperlipidaemia, unspecified	0.000	0.948	0.052
E85.9 Amyloidosis, unspecified	0.001	0.949	0.050
O03.8 Complete or unspecified, with other and unspecified complications	0.051	0.949	0.000
O62 Abnormalities of forces of labour	0.051	0.949	0.000
O62.2 Other uterine inertia	0.051	0.949	0.000
E78.6 Lipoprotein deficiency	0.000	0.949	0.050
E78.3 Hyperchylomicronaemia	0.000	0.949	0.050
O20-O29 Other maternal disorders predominantly related to pregnancy	0.051	0.949	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.000	0.950	0.050
I67.1 Cerebral aneurysm, nonruptured	0.000	0.950	0.050
E87.3 Alkalosis	0.000	0.952	0.048
O24 Diabetes mellitus in pregnancy	0.047	0.953	0.000
O80-O84 Delivery	0.047	0.953	0.000
I63.9 Cerebral infarction, unspecified	0.000	0.953	0.047
I67 Other cerebrovascular diseases	0.000	0.954	0.046
E78.8 Other disorders of lipoprotein metabolism	0.000	0.954	0.046
O70.2 Third degree perineal laceration during delivery	0.046	0.954	0.000
O03.3 Incomplete, with other and unspecified complications	0.045	0.955	0.000
I63 Cerebral infarction	0.000	0.955	0.045
O03.1 Incomplete, complicated by delayed or excessive haemorrhage	0.044	0.956	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.044	0.956	0.000
O81 Single delivery by forceps and vacuum extractor	0.044	0.956	0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.000	0.956	0.044
I60-I69 Cerebrovascular diseases	0.000	0.957	0.043
O03.7 Complete or unspecified, complicated by embolism	0.043	0.957	0.000
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.043	0.957	0.000
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.043	0.957	0.000
O03.2 Incomplete, complicated by embolism	0.043	0.957	0.000
O03.0 Incomplete, complicated by genital tract and pelvic infection	0.043	0.957	0.000
O62.0 Primary inadequate contractions	0.042	0.958	0.000
O70.3 Fourth degree perineal laceration during delivery	0.042	0.958	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.042	0.958	0.000
I69 Sequelae of cerebrovascular disease	0.000	0.959	0.041
O66 Other obstructed labour	0.041	0.959	0.000
I12.0 Hypertensive renal disease with renal failure	0.000	0.959	0.041
O61 Failed induction of labour	0.041	0.959	0.000
O24.9 Diabetes mellitus in pregnancy, unspecified	0.041	0.959	0.000
E78.4 Other hyperlipidaemia	0.000	0.959	0.041
O85-O92 Complications predominantly related to the puerperium	0.041	0.959	0.000
O28 Abnormal findings on antenatal screening of mother	0.040	0.960	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.960	0.040
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.040	0.960	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.000	0.960	0.040
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.961	0.039
O74 Complications of anaesthesia during labour and delivery	0.039	0.961	0.000
O70.9 Perineal laceration during delivery, unspecified	0.039	0.961	0.000
O26.9 Pregnancy-related condition, unspecified	0.039	0.961	0.000
I67.9 Cerebrovascular disease, unspecified	0.000	0.961	0.039
O60 Preterm delivery	0.038	0.961	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.000	0.962	0.038
O65 Obstructed labour due to maternal pelvic abnormality	0.038	0.962	0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.038	0.962	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.038	0.962	0.000
O81.3 Other and unspecified forceps delivery	0.038	0.962	0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.038	0.962	0.000
O08 Complications following abortion and ectopic and molar pregnancy	0.038	0.962	0.000
O07 Failed attempted abortion	0.038	0.962	0.000
O06 Unspecified abortion	0.038	0.962	0.000
O05 Other abortion	0.038	0.962	0.000
O01 Hydatidiform mole	0.038	0.962	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.000	0.962	0.038
O81.0 Low forceps delivery	0.037	0.963	0.000
O20 Haemorrhage in early pregnancy	0.037	0.963	0.000
O82 Single delivery by Caesarean section	0.037	0.963	0.000
O62.9 Abnormality of forces of labour, unspecified	0.037	0.963	0.000
O62.8 Other abnormalities of forces of labour	0.037	0.963	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.037	0.963	0.000
O21 Excessive vomiting in pregnancy	0.036	0.963	0.000
O29 Complications of anaesthesia during pregnancy	0.036	0.963	0.000
O25 Malnutrition in pregnancy	0.036	0.963	0.000
O62.1 Secondary uterine inertia	0.036	0.964	0.000
E87.4 Mixed disorder of acid-base balance	0.000	0.964	0.036
O26.2 Pregnancy care of habitual aborter	0.036	0.964	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.036	0.964	0.000
O22 Venous complications in pregnancy	0.036	0.964	0.000
O71 Other obstetric trauma	0.035	0.965	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.000	0.965	0.035
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.035	0.965	0.000
O86 Other puerperal infections	0.035	0.965	0.000
O62.3 Precipitate labour	0.035	0.965	0.000
O81.4 Vacuum extractor delivery	0.034	0.966	0.000
O73 Retained placenta and membranes, without haemorrhage	0.034	0.966	0.000
O24.3 Pre-existing diabetes mellitus, unspecified	0.034	0.966	0.000
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.034	0.966	0.000
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.034	0.966	0.000
O84 Multiple delivery	0.034	0.966	0.000
O83 Other assisted single delivery	0.034	0.966	0.000
E87.6 Hypokalaemia	0.000	0.966	0.034
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.966	0.033
I67.7 Cerebral arteritis, not elsewhere classified	0.000	0.967	0.033
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.000	0.967	0.033
I67.5 Moyamoya disease	0.000	0.967	0.033
I67.4 Hypertensive encephalopathy	0.000	0.967	0.033
I67.3 Progressive vascular leukoencephalopathy	0.000	0.967	0.033
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.033	0.967	0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.033	0.967	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.033	0.967	0.000
O72 Postpartum haemorrhage	0.033	0.967	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.000	0.968	0.032
E87.2 Acidosis	0.000	0.968	0.032
O61.0 Failed medical induction of labour	0.032	0.968	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.000	0.968	0.032
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.000	0.968	0.032
O04 Medical abortion	0.032	0.968	0.000
I67.2 Cerebral atherosclerosis	0.000	0.968	0.032
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.032	0.968	0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.032	0.968	0.000
O26.5 Maternal hypotension syndrome	0.032	0.968	0.000
O26.4 Herpes gestationis	0.032	0.968	0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.032	0.968	0.000
O26.1 Low weight gain in pregnancy	0.032	0.968	0.000
O26.0 Excessive weight gain in pregnancy	0.032	0.968	0.000
O81.5 Delivery by combination of forceps and vacuum extractor	0.032	0.968	0.000
O81.2 Mid-cavity forceps with rotation	0.032	0.968	0.000
O81.1 Mid-cavity forceps delivery	0.032	0.968	0.000
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.032	0.968	0.000
O66.4 Failed trial of labour, unspecified	0.031	0.969	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.031	0.969	0.000
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.031	0.969	0.000
O85 Puerperal sepsis	0.031	0.969	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.031	0.969	0.000
O14.9 Preeclampsia, unspecified	0.031	0.969	0.000
O66.0 Obstructed labour due to shoulder dystocia	0.031	0.969	0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.031	0.969	0.000
O87 Venous complications in the puerperium	0.030	0.970	0.000
O86.4 Pyrexia of unknown origin following delivery	0.030	0.970	0.000
O02 Other abnormal products of conception	0.030	0.970	0.000
O66.9 Obstructed labour, unspecified	0.030	0.970	0.000
O66.8 Other specified obstructed labour	0.030	0.970	0.000
O66.3 Obstructed labour due to other abnormalities of foetus	0.030	0.970	0.000
O66.2 Obstructed labour due to unusually large foetus	0.030	0.970	0.000
O66.1 Obstructed labour due to locked twins	0.030	0.970	0.000
O67.9 Intrapartum haemorrhage, unspecified	0.030	0.970	0.000
O61.9 Failed induction of labour, unspecified	0.030	0.970	0.000
O61.8 Other failed induction of labour	0.030	0.970	0.000
O61.1 Failed instrumental induction of labour	0.030	0.970	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.030	0.970	0.000
O91 Infections of breast associated with childbirth	0.029	0.970	0.000
O88 Obstetric embolism	0.029	0.970	0.000
O20.8 Other haemorrhage in early pregnancy	0.029	0.971	0.000
O82.0 Delivery by elective Caesarean section	0.029	0.971	0.000
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.029	0.971	0.000
O28.8 Other abnormal findings on antenatal screening of mother	0.029	0.971	0.000
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.029	0.971	0.000
O28.4 Abnormal radiological finding on antenatal screening of mother	0.029	0.971	0.000
O28.2 Abnormal cytological finding on antenatal screening of mother	0.029	0.971	0.000
O28.0 Abnormal haematological finding on antenatal screening of mother	0.029	0.971	0.000
E85.4 Organ-limited amyloidosis	0.002	0.971	0.027
I63.8 Other cerebral infarction	0.000	0.971	0.029
O72.2 Delayed and secondary postpartum haemorrhage	0.029	0.971	0.000
O89 Complications of anaesthesia during the puerperium	0.029	0.971	0.000
O23 Infections of genito-urinary tract in pregnancy	0.029	0.971	0.000
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.029	0.971	0.000
O67.8 Other intrapartum haemorrhage	0.029	0.971	0.000
O67.0 Intrapartum haemorrhage with coagulation defect	0.029	0.971	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.000	0.971	0.028
M19.94 Arthrosis, unspecified (Hand)	0.029	0.971	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.000	0.971	0.028
O20.0 Threatened abortion	0.029	0.971	0.000
O82.9 Delivery by Caesarean section, unspecified	0.028	0.972	0.000
O74.9 Complication of anaesthesia during labour and delivery, unspecified	0.028	0.972	0.000
O74.8 Other complications of anaesthesia during labour and delivery	0.028	0.972	0.000
O74.7 Failed or difficult intubation during labour and delivery	0.028	0.972	0.000
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery	0.028	0.972	0.000
O74.4 Toxic reaction to local anaesthesia during labour and delivery	0.028	0.972	0.000
O74.3 Central nervous system complications of anaesthesia during labour and delivery	0.028	0.972	0.000
O74.2 Cardiac complications of anaesthesia during labour and delivery	0.028	0.972	0.000
O74.1 Other pulmonary complications of anaesthesia during labour and delivery	0.028	0.972	0.000
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery	0.028	0.972	0.000
O60.3 Preterm delivery without spontaneous labour	0.028	0.972	0.000
O60.2 Preterm spontaneous labour with term delivery	0.028	0.972	0.000
O60.1 Preterm spontaneous labour with preterm delivery	0.028	0.972	0.000
O60.0 Preterm labour without delivery	0.028	0.972	0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.028	0.972	0.000
O92 Other disorders of breast and lactation associated with childbirth	0.028	0.972	0.000
I60 Subarachnoid haemorrhage	0.000	0.972	0.028
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.028	0.972	0.000
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.028	0.972	0.000
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.028	0.972	0.000
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.028	0.972	0.000
O65.2 Obstructed labour due to pelvic inlet contraction	0.028	0.972	0.000
O65.1 Obstructed labour due to generally contracted pelvis	0.028	0.972	0.000
O65.0 Obstructed labour due to deformed pelvis	0.028	0.972	0.000
O21.9 Vomiting of pregnancy, unspecified	0.027	0.972	0.000
O71.8 Other specified obstetric trauma	0.027	0.973	0.000
O01.9 Hydatidiform mole, unspecified	0.027	0.973	0.000
O01.1 Incomplete and partial hydatidiform mole	0.027	0.973	0.000
O01.0 Classical hydatidiform mole	0.027	0.973	0.000
O05.9 Complete or unspecified, without complication	0.027	0.973	0.000
O05.8 Complete or unspecified, with other and unspecified complications	0.027	0.973	0.000
O05.7 Complete or unspecified, complicated by embolism	0.027	0.973	0.000
O05.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.027	0.973	0.000
O05.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.027	0.973	0.000
O05.4 Incomplete, without complication	0.027	0.973	0.000
O05.3 Incomplete, with other and unspecified complications	0.027	0.973	0.000
O05.2 Incomplete, complicated by embolism	0.027	0.973	0.000
O05.1 Incomplete, complicated by delayed or excessive haemorrhage	0.027	0.973	0.000
O05.0 Incomplete, complicated by genital tract and pelvic infection	0.027	0.973	0.000
O06.9 Complete or unspecified, without complication	0.027	0.973	0.000
O06.8 Complete or unspecified, with other and unspecified complications	0.027	0.973	0.000
O06.7 Complete or unspecified, complicated by embolism	0.027	0.973	0.000
O06.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.027	0.973	0.000
O06.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.027	0.973	0.000
O06.4 Incomplete, without complication	0.027	0.973	0.000
O06.3 Incomplete, with other and unspecified complications	0.027	0.973	0.000
O06.2 Incomplete, complicated by embolism	0.027	0.973	0.000
O06.1 Incomplete, complicated by delayed or excessive haemorrhage	0.027	0.973	0.000
O06.0 Incomplete, complicated by genital tract and pelvic infection	0.027	0.973	0.000
O07.9 Other and unspecified failed attempted abortion, without complication	0.027	0.973	0.000
O07.8 Other and unspecified failed attempted abortion, with other and unspecified complications	0.027	0.973	0.000
O07.7 Other and unspecified failed attempted abortion, complicated by embolism	0.027	0.973	0.000
O07.6 Other and unspecified failed attempted abortion, complicated by delayed or excessive haemorrhage	0.027	0.973	0.000
O07.5 Other and unspecified failed attempted abortion, complicated by genital tract and pelvic infection	0.027	0.973	0.000
O07.4 Failed medical abortion, without complication	0.027	0.973	0.000
O07.3 Failed medical abortion, with other and unspecified complications	0.027	0.973	0.000
O07.2 Failed medical abortion, complicated by embolism	0.027	0.973	0.000
O07.1 Failed medical abortion, complicated by delayed or excessive haemorrhage	0.027	0.973	0.000
O07.0 Failed medical abortion, complicated by genital tract and pelvic infection	0.027	0.973	0.000
O08.9 Complication following abortion and ectopic and molar pregnancy, unspecified	0.027	0.973	0.000
O08.8 Other complications following abortion and ectopic and molar pregnancy	0.027	0.973	0.000
O08.7 Other venous complications following abortion and ectopic and molar pregnancy	0.027	0.973	0.000
O08.6 Damage to pelvic organs and tissues following abortion and ectopic and molar pregnancy	0.027	0.973	0.000
O08.5 Metabolic disorders following abortion and ectopic and molar pregnancy	0.027	0.973	0.000
O08.4 Renal failure following abortion and ectopic and molar pregnancy	0.027	0.973	0.000
O08.3 Shock following abortion and ectopic and molar pregnancy	0.027	0.973	0.000
O08.2 Embolism following abortion and ectopic and molar pregnancy	0.027	0.973	0.000
O08.1 Delayed or excessive haemorrhage following abortion and ectopic and molar pregnancy	0.027	0.973	0.000
O08.0 Genital tract and pelvic infection following abortion and ectopic and molar pregnancy	0.027	0.973	0.000
O86.1 Other infection of genital tract following delivery	0.027	0.973	0.000
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.027	0.973	0.000
O21.8 Other vomiting complicating pregnancy	0.027	0.973	0.000
O86.2 Urinary tract infection following delivery	0.027	0.973	0.000
O21.2 Late vomiting of pregnancy	0.027	0.973	0.000
O00 Ectopic pregnancy	0.027	0.973	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.000	0.973	0.027
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.973	0.027
O82.8 Other single delivery by Caesarean section	0.027	0.973	0.000
O82.2 Delivery by Caesarean hysterectomy	0.027	0.973	0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.026	0.973	0.000
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.027	0.973	0.000
O15 Eclampsia	0.027	0.973	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.027	0.973	0.000
O04.9 Complete or unspecified, without complication	0.027	0.973	0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.026	0.974	0.000
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.026	0.974	0.000
O29.8 Other complications of anaesthesia during pregnancy	0.026	0.974	0.000
O29.6 Failed or difficult intubation during pregnancy	0.026	0.974	0.000
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.026	0.974	0.000
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.026	0.974	0.000
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.026	0.974	0.000
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.026	0.974	0.000
O29.1 Cardiac complications of anaesthesia during pregnancy	0.026	0.974	0.000
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.026	0.974	0.000
O80 Single spontaneous delivery	0.026	0.974	0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.026	0.974	0.000
O97 Death from sequelae of direct obstetric causes	0.026	0.974	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.026	0.974	0.000
O95 Obstetric death of unspecified cause	0.026	0.974	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.026	0.974	0.000
I67.8 Other specified cerebrovascular diseases	0.000	0.974	0.026
O22.9 Venous complication in pregnancy, unspecified	0.026	0.974	0.000
O22.8 Other venous complications in pregnancy	0.026	0.974	0.000
O22.5 Cerebral venous thrombosis in pregnancy	0.026	0.974	0.000
O22.3 Deep phlebothrombosis in pregnancy	0.026	0.974	0.000
O22.2 Superficial thrombophlebitis in pregnancy	0.026	0.974	0.000
O22.1 Genital varices in pregnancy	0.026	0.974	0.000
O22.0 Varicose veins of lower extremity in pregnancy	0.026	0.974	0.000
O69.9 Labour and delivery complicated by cord complication, unspecified	0.026	0.974	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.026	0.974	0.000
O82.1 Delivery by emergency Caesarean section	0.026	0.974	0.000
O71.9 Obstetric trauma, unspecified	0.025	0.974	0.000
O71.7 Obstetric haematoma of pelvis	0.025	0.974	0.000
O71.6 Obstetric damage to pelvic joints and ligaments	0.025	0.974	0.000
O71.5 Other obstetric injury to pelvic organs	0.025	0.974	0.000
O71.3 Obstetric laceration of cervix	0.025	0.974	0.000
O71.2 Postpartum inversion of uterus	0.025	0.974	0.000
O71.1 Rupture of uterus during labour	0.025	0.974	0.000
O71.0 Rupture of uterus before onset of labour	0.025	0.974	0.000
O22.4 Haemorrhoids in pregnancy	0.025	0.975	0.000
O86.8 Other specified puerperal infections	0.025	0.975	0.000
O86.3 Other genito-urinary tract infections following delivery	0.025	0.975	0.000
O64.8 Obstructed labour due to other malposition and malpresentation	0.025	0.975	0.000
I61 Intracerebral haemorrhage	0.000	0.975	0.025
O12.0 Gestational oedema	0.025	0.975	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.025	0.975	0.000
O83.9 Assisted single delivery, unspecified	0.024	0.975	0.000
O83.8 Other specified assisted single delivery	0.024	0.975	0.000
O83.4 Destructive operation for delivery	0.024	0.975	0.000
O83.3 Delivery of viable foetus in abdominal pregnancy	0.024	0.975	0.000
O83.2 Other manipulation-assisted delivery	0.024	0.975	0.000
O83.1 Other assisted breech delivery	0.024	0.975	0.000
O83.0 Breech extraction	0.024	0.975	0.000
O84.9 Multiple delivery, unspecified	0.024	0.975	0.000
O84.8 Other multiple delivery	0.024	0.975	0.000
O84.2 Multiple delivery, all by Caesarean section	0.024	0.975	0.000
O84.1 Multiple delivery, all by forceps and vacuum extractor	0.024	0.975	0.000
O84.0 Multiple delivery, all spontaneous	0.024	0.975	0.000
O14.1 Severe preeclampsia	0.024	0.975	0.000
O90 Complications of the puerperium, not elsewhere classified	0.024	0.976	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.024	0.976	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.000	0.976	0.024
O14.2 HELLP syndrome	0.024	0.976	0.000
E78.2 Mixed hyperlipidaemia	0.000	0.976	0.024
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.024	0.976	0.000
O14.0 Moderate preeclampsia	0.024	0.976	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations