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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7089656
log Bayes Factor = 10.3905
Chromosome 10   position 22,284,140  (GRCh37) Explore rs7089656 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E65-E68 Obesity and other hyperalimentation
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
E66 Obesity
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
J90-J94 Other diseases of pleura
1.000 0.000 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.999 0.001 0.000
E66.8 Other obesity
0.999 0.001 0.000
J92 Pleural plaque
0.999 0.001 0.000
I10 Essential (primary) hypertension
0.998 0.002 0.000
H10-H13 Disorders of conjunctiva
0.996 0.004 0.000
I10-I15 Hypertensive diseases
0.996 0.004 0.000
Chapter II Neoplasms
0.996 0.004 0.000
E20-E35 Disorders of other endocrine glands
0.995 0.005 0.000
D32 Benign neoplasm of meninges
0.993 0.007 0.000
D32.0 Cerebral meninges
0.993 0.007 0.000
H11 Other disorders of conjunctiva
0.992 0.008 0.000
D10-D36 Benign neoplasms
0.991 0.009 0.000
J92.0 Pleural plaque with presence of asbestos
0.991 0.009 0.000
D00-D09 In situ neoplasms
0.991 0.009 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.991 0.009 0.000
Chapter V Mental and behavioural disorders
0.989 0.011 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.988 0.012 0.000
C43.7 Malignant melanoma of lower limb, including hip
0.988 0.012 0.000
C43 Malignant melanoma of skin
0.987 0.013 0.000
Chapter XXI Factors influencing health status and contact with health services
0.986 0.014 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.986 0.014 0.000
J40-J47 Chronic lower respiratory diseases
0.985 0.015 0.000
J91 Pleural effusion in conditions classified elsewhere
0.984 0.016 0.000
H18 Other disorders of cornea
0.984 0.016 0.000
Z86 Personal history of certain other diseases
0.983 0.017 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.981 0.019 0.000
D35.1 Parathyroid gland
0.980 0.020 0.000
Z86.7 Personal history of diseases of the circulatory system
0.975 0.025 0.000
D04 Carcinoma in situ of skin
0.974 0.026 0.000
J92.9 Pleural plaque without asbestos
0.973 0.027 0.000
J46 Status asthmaticus
0.972 0.028 0.000
Z80 Family history of malignant neoplasm
0.972 0.028 0.000
Z86.0 Personal history of other neoplasms
0.971 0.029 0.000
E21.3 Hyperparathyroidism, unspecified
0.968 0.032 0.000
E66.9 Obesity, unspecified
0.967 0.033 0.000
D04.3 Skin of other and unspecified parts of face
0.965 0.035 0.000
Z98 Other postsurgical states
0.965 0.035 0.000
E50-E64 Other nutritional deficiencies
0.959 0.041 0.000
H11.0 Pterygium
0.955 0.045 0.000
Z80.3 Family history of malignant neoplasm of breast
0.955 0.045 0.000
Chapter IX Diseases of the circulatory system
0.955 0.045 0.000
I12 Hypertensive renal disease
0.952 0.048 0.000
Z98.1 Arthrodesis status
0.951 0.049 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.951 0.049 0.000
H16 Keratitis
0.947 0.053 0.000
D03 Melanoma in situ
0.945 0.055 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.941 0.059 0.000
F30-F39 Mood [affective] disorders
0.940 0.060 0.000
F31 Bipolar affective disorder
0.939 0.061 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.931 0.069 0.000
E61 Deficiency of other nutrient elements
0.928 0.072 0.000
I15 Secondary hypertension
0.928 0.072 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.926 0.074 0.000
D12.8 Rectum
0.925 0.075 0.000
Z88.2 Personal history of allergy to sulphonamides
0.919 0.081 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.917 0.083 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.914 0.086 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.913 0.087 0.000
D32.9 Meninges, unspecified
0.910 0.090 0.000
E61.1 Iron deficiency
0.910 0.090 0.000
E28 Ovarian dysfunction
0.906 0.094 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.904 0.096 0.000
C43.5 Malignant melanoma of trunk
0.901 0.099 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.898 0.102 0.000
J60-J70 Lung diseases due to external agents
0.897 0.102 0.000
H17 Corneal scars and opacities
0.895 0.105 0.000
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs
0.894 0.106 0.000
J42 Unspecified chronic bronchitis
0.893 0.107 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.890 0.110 0.000
Z98.8 Other specified postsurgical states
0.885 0.115 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.885 0.115 0.000
D31 Benign neoplasm of eye and adnexa
0.884 0.116 0.000
H11.4 Other conjunctival vascular disorders and cysts
0.884 0.116 0.000
H55-H59 Other disorders of eye and adnexa
0.883 0.117 0.000
E23 Hypofunction and other disorders of pituitary gland
0.881 0.119 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.880 0.120 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.879 0.121 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.877 0.123 0.000
D29 Benign neoplasm of male genital organs
0.877 0.123 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.874 0.126 0.000
Z97 Presence of other devices
0.871 0.129 0.000
I12.9 Hypertensive renal disease without renal failure
0.868 0.132 0.000
H11.9 Disorder of conjunctiva, unspecified
0.868 0.132 0.000
D32.1 Spinal meninges
0.867 0.133 0.000
H21 Other disorders of iris and ciliary body
0.866 0.134 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.862 0.138 0.000
Z80.8 Family history of malignant neoplasm of other organs or systems
0.858 0.142 0.000
H55 Nystagmus and other irregular eye movements
0.858 0.142 0.000
H18.2 Other corneal oedema
0.857 0.142 0.000
D12.6 Colon, unspecified
0.857 0.143 0.000
E65 Localised adiposity
0.856 0.144 0.000
H11.1 Conjunctival degenerations and deposits
0.856 0.144 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.854 0.146 0.000
Chapter XXII Codes for special purposes
0.853 0.147 0.000
I15.1 Hypertension secondary to other renal disorders
0.852 0.148 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.850 0.150 0.000
I12.0 Hypertensive renal disease with renal failure
0.849 0.151 0.000
H18.6 Keratoconus
0.848 0.152 0.000
Z57 Occupational exposure to risk-factors
0.848 0.152 0.000
H16.0 Corneal ulcer
0.848 0.152 0.000
D30 Benign neoplasm of urinary organs
0.846 0.154 0.000
H18.9 Disorder of cornea, unspecified
0.846 0.154 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.844 0.156 0.000
H18.8 Other specified disorders of cornea
0.839 0.161 0.000
H18.5 Hereditary corneal dystrophies
0.838 0.162 0.000
D03.7 Melanoma in situ of lower limb, including hip
0.837 0.163 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.837 0.163 0.000
H17.9 Corneal scar and opacity, unspecified
0.837 0.163 0.000
D03.3 Melanoma in situ of other and unspecified parts of face
0.836 0.164 0.000
F70-F79 Mental retardation
0.836 0.164 0.000
Z72 Problems related to lifestyle
0.832 0.168 0.000
Z72.0 Tobacco use
0.831 0.169 0.000
H13 Disorders of conjunctiva in diseases classified elsewhere
0.829 0.171 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.827 0.173 0.000
Z90.3 Acquired absence of part of stomach
0.825 0.175 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.823 0.177 0.000
D29.1 Prostate
0.822 0.178 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.822 0.178 0.000
D04.7 Skin of lower limb, including hip
0.822 0.178 0.000
Z90.2 Acquired absence of lung [part of]
0.821 0.179 0.000
H16.1 Other superficial keratitis without conjunctivitis
0.820 0.180 0.000
E34 Other endocrine disorders
0.819 0.181 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.818 0.182 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.816 0.184 0.000
Z94 Transplanted organ and tissue status
0.815 0.185 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.814 0.186 0.000
F25 Schizoaffective disorders
0.813 0.187 0.000
E21.0 Primary hyperparathyroidism
0.811 0.189 0.000
L20-L30 Dermatitis and eczema
0.810 0.190 0.000
E23.0 Hypopituitarism
0.806 0.194 0.000
Z86.4 Personal history of psychoactive substance abuse
0.806 0.194 0.000
Q50-Q56 Congenital malformations of genital organs
0.805 0.195 0.000
F20 Schizophrenia
0.804 0.196 0.000
D11 Benign neoplasm of major salivary glands
0.804 0.196 0.000
Z58 Problems related to physical environment
0.804 0.196 0.000
D06 Carcinoma in situ of cervix uteri
0.800 0.200 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.800 0.200 0.000
Q60-Q64 Congenital malformations of the urinary system
0.799 0.201 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.797 0.203 0.000
H11.8 Other specified disorders of conjunctiva
0.796 0.204 0.000
F60-F69 Disorders of adult personality and behaviour
0.795 0.205 0.000
L50-L54 Urticaria and erythema
0.794 0.206 0.000
J93 Pneumothorax
0.794 0.206 0.000
E21.2 Other hyperparathyroidism
0.794 0.206 0.000
H18.0 Corneal pigmentations and deposits
0.791 0.208 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.791 0.209 0.000
E28.2 Polycystic ovarian syndrome
0.791 0.209 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.790 0.210 0.000
D37.1 Stomach
0.790 0.210 0.000
I11 Hypertensive heart disease
0.785 0.215 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.785 0.215 0.000
D31.0 Conjunctiva
0.785 0.215 0.000
Z90.7 Acquired absence of genital organ(s)
0.784 0.216 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.781 0.219 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.780 0.220 0.000
Z97.5 Presence of (intra-uterine) contraceptive device
0.780 0.220 0.000
F80-F89 Disorders of psychological development
0.779 0.221 0.000
L29 Pruritus
0.779 0.221 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.778 0.222 0.000
D04.0 Skin of lip
0.777 0.223 0.000
E55 Vitamin D deficiency
0.776 0.224 0.000
D04.4 Skin of scalp and neck
0.776 0.224 0.000
J94 Other pleural conditions
0.775 0.225 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.774 0.226 0.000
E66.0 Obesity due to excess calories
0.773 0.227 0.000
D37.4 Colon
0.772 0.228 0.000
Z97.4 Presence of external hearing-aid
0.772 0.228 0.000
J95-J99 Other diseases of the respiratory system
0.770 0.230 0.000
Z94.7 Corneal transplant status
0.769 0.230 0.000
E63 Other nutritional deficiencies
0.769 0.231 0.000
J44 Other chronic obstructive pulmonary disease
0.768 0.232 0.000
Z99.2 Dependence on renal dialysis
0.767 0.233 0.000
Z75 Problems related to medical facilities and other health care
0.766 0.234 0.000
D30.3 Bladder
0.765 0.235 0.000
E28.3 Primary ovarian failure
0.765 0.235 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.764 0.236 0.000
H18.1 Bullous keratopathy
0.762 0.238 0.000
L29.9 Pruritus, unspecified
0.761 0.239 0.000
D26 Other benign neoplasms of uterus
0.760 0.240 0.000
H11.2 Conjunctival scars
0.758 0.242 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.752 0.248 0.000
H50 Other strabismus
0.752 0.248 0.000
I15.8 Other secondary hypertension
0.751 0.249 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.751 0.249 0.000
F31.7 Bipolar affective disorder, currently in remission
0.750 0.250 0.000
D03.2 Melanoma in situ of ear and external auricular canal
0.748 0.252 0.000
C43.4 Malignant melanoma of scalp and neck
0.746 0.254 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.746 0.254 0.000
D03.4 Melanoma in situ of scalp and neck
0.745 0.255 0.000
H16.3 Interstitial and deep keratitis
0.744 0.256 0.000
Z88.5 Personal history of allergy to narcotic agent
0.743 0.257 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.743 0.257 0.000
Z57.5 Occupational exposure to toxic agents in other industries
0.742 0.258 0.000
J47 Bronchiectasis
0.742 0.258 0.000
Z60 Problems related to social environment
0.741 0.259 0.000
F51 Nonorganic sleep disorders
0.740 0.260 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.738 0.262 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.737 0.263 0.000
E23.7 Disorder of pituitary gland, unspecified
0.736 0.264 0.000
Q00-Q07 Congenital malformations of the nervous system
0.735 0.265 0.000
D11.7 Other major salivary glands
0.733 0.267 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.732 0.268 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.732 0.268 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.731 0.269 0.000
H18.3 Changes in corneal membranes
0.731 0.269 0.000
Z94.1 Heart transplant status
0.731 0.269 0.000
H21.1 Other vascular disorders of iris and ciliary body
0.731 0.269 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.728 0.272 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.726 0.274 0.000
F79 Unspecified mental retardation
0.726 0.274 0.000
Z57.3 Occupational exposure to other air contaminants
0.721 0.279 0.000
E31 Polyglandular dysfunction
0.720 0.279 0.000
D37.7 Other digestive organs
0.718 0.282 0.000
E67 Other hyperalimentation
0.717 0.283 0.000
E68 Sequelae of hyperalimentation
0.717 0.283 0.000
E66.1 Drug-induced obesity
0.717 0.283 0.000
L52 Erythema nodosum
0.717 0.283 0.000
E26 Hyperaldosteronism
0.717 0.283 0.000
J20-J22 Other acute lower respiratory infections
0.717 0.283 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.716 0.284 0.000
J98 Other respiratory disorders
0.716 0.284 0.000
H16.9 Keratitis, unspecified
0.715 0.285 0.000
I13 Hypertensive heart and renal disease
0.714 0.286 0.000
L53 Other erythematous conditions
0.714 0.286 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.713 0.287 0.000
E32 Diseases of thymus
0.713 0.287 0.000
E30 Disorders of puberty, not elsewhere classified
0.713 0.287 0.000
E25 Adrenogenital disorders
0.713 0.287 0.000
H16.8 Other keratitis
0.713 0.287 0.000
H15 Disorders of sclera
0.713 0.287 0.000
D26.1 Corpus uteri
0.713 0.287 0.000
C43.1 Malignant melanoma of eyelid, including canthus
0.711 0.289 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.711 0.289 0.000
D19 Benign neoplasm of mesothelial tissue
0.711 0.289 0.000
E21.4 Other specified disorders of parathyroid gland
0.710 0.290 0.000
F20.9 Schizophrenia, unspecified
0.709 0.291 0.000
H13.3 Ocular pemphigoid
0.709 0.291 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.709 0.291 0.000
J45 Asthma
0.709 0.291 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.708 0.292 0.000
C43.8 Overlapping malignant melanoma of skin
0.708 0.292 0.000
C43.0 Malignant melanoma of lip
0.708 0.292 0.000
D37.3 Appendix
0.707 0.293 0.000
J41 Simple and mucopurulent chronic bronchitis
0.706 0.294 0.000
H18.7 Other corneal deformities
0.705 0.295 0.000
D33.2 Brain, unspecified
0.704 0.296 0.000
D35.9 Endocrine gland, unspecified
0.703 0.297 0.000
D35.8 Pluriglandular involvement
0.703 0.297 0.000
D35.7 Other specified endocrine glands
0.703 0.297 0.000
D35.6 Aortic body and other paraganglia
0.703 0.297 0.000
D35.5 Carotid body
0.703 0.297 0.000
D35.4 Pineal gland
0.703 0.297 0.000
D35.3 Craniopharyngeal duct
0.703 0.297 0.000
I00-I02 Acute rheumatic fever
0.703 0.297 0.000
D06.0 Endocervix
0.701 0.299 0.000
J93.9 Pneumothorax, unspecified
0.701 0.299 0.000
H47.2 Optic atrophy
0.700 0.300 0.000
D04.8 Skin of other sites
0.698 0.302 0.000
Z75.1 Person awaiting admission to adequate facility elsewhere
0.698 0.302 0.000
H22.1 Iridocyclitis in other diseases classified elsewhere
0.697 0.303 0.000
E29 Testicular dysfunction
0.696 0.304 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.696 0.304 0.000
E20 Hypoparathyroidism
0.695 0.305 0.000
Z80.6 Family history of leukaemia
0.695 0.305 0.000
J98.1 Pulmonary collapse
0.695 0.305 0.000
H21.4 Pupillary membranes
0.694 0.306 0.000
I15.0 Renovascular hypertension
0.694 0.306 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.693 0.307 0.000
F80 Specific developmental disorders of speech and language
0.692 0.308 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.692 0.308 0.000
D31.3 Choroid
0.689 0.311 0.000
F23 Acute and transient psychotic disorders
0.688 0.312 0.000
F31.9 Bipolar affective disorder, unspecified
0.688 0.312 0.000
I11.9 Hypertensive heart disease without (congestive) heart failure
0.688 0.312 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.687 0.313 0.000
E50 Vitamin A deficiency
0.687 0.313 0.000
E60 Dietary zinc deficiency
0.687 0.313 0.000
E59 Dietary selenium deficiency
0.687 0.313 0.000
E54 Ascorbic acid deficiency
0.687 0.313 0.000
E52 Niacin deficiency [pellagra]
0.687 0.313 0.000
Z57.2 Occupational exposure to dust
0.687 0.313 0.000
L21 Seborrhoeic dermatitis
0.686 0.314 0.000
D04.1 Skin of eyelid, including canthus
0.684 0.316 0.000
Q54 Hypospadias
0.684 0.316 0.000
H10 Conjunctivitis
0.683 0.317 0.000
Z60.9 Problem related to social environment, unspecified
0.683 0.317 0.000
H21.2 Degeneration of iris and ciliary body
0.683 0.317 0.000
D09 Carcinoma in situ of other and unspecified sites
0.683 0.317 0.000
L28 Lichen simplex chronicus and prurigo
0.681 0.318 0.000
Z74 Problems related to care-provider dependency
0.680 0.320 0.000
H16.4 Corneal neovascularisation
0.679 0.321 0.000
F25.0 Schizoaffective disorder, manic type
0.679 0.321 0.000
D03.9 Melanoma in situ, unspecified
0.678 0.322 0.000
D03.8 Melanoma in situ of other sites
0.678 0.322 0.000
D03.1 Melanoma in situ of eyelid, including canthus
0.678 0.322 0.000
D03.0 Melanoma in situ of lip
0.678 0.322 0.000
E34.9 Endocrine disorder, unspecified
0.677 0.323 0.000
Z61 Problems related to negative life events in childhood
0.676 0.324 0.000
H40-H42 Glaucoma
0.676 0.324 0.000
Z58.7 Exposure to tobacco smoke
0.675 0.325 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.675 0.325 0.000
F38 Other mood [affective] disorders
0.674 0.326 0.000
F34 Persistent mood [affective] disorders
0.674 0.326 0.000
Z97.3 Presence of spectacles and contact lenses
0.673 0.327 0.000
Z82.3 Family history of stroke
0.670 0.330 0.000
E34.3 Short stature, not elsewhere classified
0.670 0.330 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.670 0.330 0.000
E58 Dietary calcium deficiency
0.670 0.330 0.000
F31.8 Other bipolar affective disorders
0.669 0.330 0.000
Q60.0 Renal agenesis, unilateral
0.669 0.331 0.000
H47.1 Papilloedema, unspecified
0.668 0.332 0.000
F53 Mental and behavioural disorders associated with the puerperium, not elsewhere classified
0.668 0.332 0.000
C64-C68 Malignant neoplasms of urinary tract
0.667 0.333 0.000
E51 Thiamine deficiency
0.666 0.334 0.000
E61.9 Deficiency of nutrient element, unspecified
0.665 0.334 0.000
E61.8 Deficiency of other specified nutrient elements
0.665 0.334 0.000
E61.7 Deficiency of multiple nutrient elements
0.665 0.334 0.000
E61.6 Vanadium deficiency
0.665 0.334 0.000
E61.5 Molybdenum deficiency
0.665 0.334 0.000
E61.4 Chromium deficiency
0.665 0.334 0.000
E61.3 Manganese deficiency
0.665 0.334 0.000
E61.0 Copper deficiency
0.665 0.334 0.000
I15.2 Hypertension secondary to endocrine disorders
0.665 0.335 0.000
Z75.5 Holiday relief care
0.665 0.335 0.000
Z58.8 Other problems related to physical environment
0.664 0.336 0.000
F25.9 Schizoaffective disorder, unspecified
0.662 0.338 0.000
F39 Unspecified mood [affective] disorder
0.662 0.338 0.000
D03.5 Melanoma in situ of trunk
0.662 0.338 0.000
Z97.2 Presence of dental prosthetic device (complete)(partial)
0.661 0.339 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.661 0.339 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.660 0.340 0.000
F51.5 Nightmares
0.660 0.340 0.000
E56 Other vitamin deficiencies
0.660 0.340 0.000
H21.9 Disorder of iris and ciliary body, unspecified
0.659 0.341 0.000
Q50.4 Embryonic cyst of Fallopian tube
0.659 0.341 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.659 0.341 0.000
C43.2 Malignant melanoma of ear and external auricular canal
0.658 0.341 0.000
Q35-Q37 Cleft lip and cleft palate
0.657 0.343 0.000
Z62 Other problems related to upbringing
0.655 0.344 0.000
Z55 Problems related to education and literacy
0.655 0.344 0.000
C43.9 Malignant melanoma of skin, unspecified
0.655 0.345 0.000
H21.0 Hyphaema
0.654 0.346 0.000
U80 Agent resistant to penicillin and related antibiotics
0.654 0.346 0.000
J20 Acute bronchitis
0.654 0.346 0.000
H21.8 Other specified disorders of iris and ciliary body
0.653 0.347 0.000
L10-L14 Bullous disorders
0.652 0.347 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.652 0.348 0.000
D29.4 Scrotum
0.652 0.348 0.000
F25.1 Schizoaffective disorder, depressive type
0.651 0.349 0.000
Z81 Family history of mental and behavioural disorders
0.651 0.349 0.000
H47.3 Other disorders of optic disk
0.651 0.349 0.000
E28.9 Ovarian dysfunction, unspecified
0.649 0.350 0.000
E28.8 Other ovarian dysfunction
0.649 0.350 0.000
E28.1 Androgen excess
0.649 0.350 0.000
E28.0 Oestrogen excess
0.649 0.350 0.000
F42 Obsessive-compulsive disorder
0.649 0.351 0.000
F50 Eating disorders
0.648 0.352 0.000
F79.9 Unspecified mental retardation (Without mention of impairment of behaviour)
0.647 0.353 0.000
F20.5 Residual schizophrenia
0.646 0.354 0.000
I15.9 Seconday hypertension, unspecified
0.646 0.354 0.000
E55.9 Vitamin D deficiency, unspecified
0.645 0.355 0.000
F28 Other nonorganic psychotic disorders
0.644 0.356 0.000
F24 Induced delusional disorder
0.644 0.356 0.000
F21 Schizotypal disorder
0.644 0.356 0.000
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.643 0.356 0.000
J66 Airway disease due to specific organic dust
0.643 0.356 0.000
J63 Pneumoconiosis due to other inorganic dusts
0.643 0.356 0.000
J62 Pneumoconiosis due to dust containing silica
0.643 0.356 0.000
J65 Pneumoconiosis associated with tuberculosis
0.643 0.356 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.642 0.357 0.000
H17.1 Other central corneal opacity
0.641 0.358 0.000
H17.0 Adherent leukoma
0.641 0.358 0.000
D05 Carcinoma in situ of breast
0.642 0.358 0.000
Z64 Problems related to certain psychosocial circumstances
0.641 0.359 0.000
F69 Unspecified disorder of adult personality and behaviour
0.640 0.359 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.640 0.360 0.000
J94.2 Haemothorax
0.640 0.360 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.639 0.361 0.000
Z82.1 Family history of blindness and visual loss
0.639 0.361 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.638 0.362 0.000
D12.7 Rectosigmoid junction
0.638 0.362 0.000
Z73 Problems related to life-management difficulty
0.637 0.363 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.637 0.363 0.000
F64 Gender identity disorders
0.636 0.364 0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues
0.635 0.364 0.000
J70 Respiratory conditions due to other external agents
0.635 0.365 0.000
H50.0 Convergent concomitant strabismus
0.634 0.366 0.000
D31.9 Eye, unspecified
0.634 0.366 0.000
D31.6 Orbit, unspecified
0.634 0.366 0.000
D31.5 Lachrymal gland and duct
0.634 0.366 0.000
D31.4 Ciliary body
0.634 0.366 0.000
D31.2 Retina
0.634 0.366 0.000
D31.1 Cornea
0.634 0.366 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.633 0.367 0.000
D44.4 Craniopharyngeal duct
0.633 0.367 0.000
E63.9 Nutritional deficiency, unspecified
0.632 0.367 0.000
Q63 Other congenital malformations of kidney
0.632 0.368 0.000
D27 Benign neoplasm of ovary
0.632 0.368 0.000
H51 Other disorders of binocular movement
0.632 0.368 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.631 0.368 0.000
E23.1 Drug-induced hypopituitarism
0.631 0.368 0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.631 0.369 0.000
F80.1 Expressive language disorder
0.629 0.371 0.000
H50.1 Divergent concomitant strabismus
0.629 0.371 0.000
D29.9 Male genital organ, unspecified
0.629 0.371 0.000
D29.7 Other male genital organs
0.629 0.371 0.000
D29.3 Epididymis
0.629 0.371 0.000
D29.2 Testis
0.629 0.371 0.000
L25 Unspecified contact dermatitis
0.628 0.372 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.627 0.373 0.000
J94.1 Fibrothorax
0.627 0.373 0.000
D04.9 Skin, unspecified
0.626 0.374 0.000
F99-F99 Unspecified mental disorder
0.625 0.374 0.000
H50.5 Heterophoria
0.624 0.376 0.000
D33.0 Brain, supratentorial
0.623 0.377 0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified
0.623 0.377 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.622 0.378 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.622 0.378 0.000
E40-E46 Malnutrition
0.621 0.378 0.000
H21.3 Cyst of iris, ciliary body and anterior chamber
0.621 0.379 0.000
L53.9 Erythematous condition, unspecified
0.621 0.379 0.000
U80.8 Agent resistant to other penicillin-related antibiotic
0.620 0.380 0.000
D44.7 Aortic body and other paraganglia
0.619 0.381 0.000
J20.9 Acute bronchitis, unspecified
0.619 0.381 0.000
Q07 Other congenital malformations of nervous system
0.618 0.382 0.000
E61.2 Magnesium deficiency
0.618 0.382 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.617 0.382 0.000
Z74.1 Need for assistance with personal care
0.617 0.383 0.000
H46 Optic neuritis
0.617 0.383 0.000
D37.0 Lip, oral cavity and pharynx
0.616 0.384 0.000
Z99.0 Dependence on aspirator
0.615 0.385 0.000
Z63 Other problems related to primary support group, including family circumstances
0.615 0.385 0.000
D02.0 Larynx
0.614 0.386 0.000
Q14 Congenital malformations of posterior segment of eye
0.614 0.386 0.000
D33.4 Spinal cord
0.612 0.388 0.000
Q52 Other congenital malformations of female genitalia
0.612 0.388 0.000
F59 Unspecified behavioural syndromes associated with physiological disturbances and physical factors
0.612 0.388 0.000
F55 Abuse of non-dependence-producing substances
0.612 0.388 0.000
F54 Psychological and behavioural factors associated with disorders or diseases classified elsewhere
0.612 0.388 0.000
D37.9 Digestive organ, unspecified
0.611 0.389 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.610 0.390 0.000
Z65 Problems related to other psychosocial circumstances
0.609 0.391 0.000
E34.0 Carcinoid syndrome
0.609 0.391 0.000
C60-C63 Malignant neoplasms of male genital organs
0.608 0.392 0.000
Z57.9 Occupational exposure to unspecified risk-factor
0.608 0.392 0.000
Z57.7 Occupational exposure to vibration
0.608 0.392 0.000
Z57.6 Occupational exposure to extreme temperature
0.608 0.392 0.000
Z57.4 Occupational exposure to toxic agents in agriculture
0.608 0.392 0.000
Z57.1 Occupational exposure to radiation
0.608 0.392 0.000
Z57.0 Occupational exposure to noise
0.608 0.392 0.000
D02.2 Bronchus and lung
0.608 0.392 0.000
D30.9 Urinary organ, unspecified
0.607 0.393 0.000
D30.7 Other urinary organs
0.607 0.393 0.000
D30.4 Urethra
0.607 0.393 0.000
D30.2 Ureter
0.607 0.393 0.000
D30.1 Renal pelvis
0.607 0.393 0.000
C65 Malignant neoplasm of renal pelvis
0.605 0.395 0.000
Z60.8 Other problems related to social environment
0.604 0.396 0.000
Q12 Congenital lens malformations
0.604 0.396 0.000
F98 Other behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.603 0.397 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.603 0.397 0.000
C69 Malignant neoplasm of eye and adnexa
0.603 0.397 0.000
D03.6 Melanoma in situ of upper limb, including shoulder
0.602 0.398 0.000
Z98.2 Presence of cerebrospinal fluid drainage device
0.602 0.398 0.000
D37.2 Small intestine
0.600 0.399 0.000
D12.0 Caecum
0.599 0.401 0.000
Z97.1 Presence of artificial limb (complete)(partial)
0.599 0.401 0.000
F78 Other mental retardation
0.599 0.401 0.000
F73 Profound mental retardation
0.599 0.401 0.000
F72 Severe mental retardation
0.599 0.401 0.000
F71 Moderate mental retardation
0.599 0.401 0.000
F70 Mild mental retardation
0.599 0.401 0.000
L21.9 Seborrhoeic dermatitis, unspecified
0.597 0.403 0.000
Z72.6 Gambling and betting
0.596 0.404 0.000
Z72.5 High-risk sexual behaviour
0.596 0.404 0.000
Z72.3 Lack of physical exercise
0.596 0.404 0.000
Q64 Other congenital malformations of urinary system
0.595 0.405 0.000
Q60.3 Renal hypoplasia, unilateral
0.595 0.405 0.000
H13.8 Other disorders of conjunctiva in diseases classified elsewhere
0.594 0.406 0.000
H13.2 Conjunctivitis in other diseases classified elsewhere
0.594 0.406 0.000
H13.1 Conjunctivitis in infectious and parasitic diseases classified elsewhere
0.594 0.406 0.000
H13.0 Filarial infection of conjunctiva
0.594 0.406 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.594 0.406 0.000
F30 Manic episode
0.593 0.407 0.000
D11.9 Major salivary gland, unspecified
0.593 0.407 0.000
Q04 Other congenital malformations of brain
0.593 0.407 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.593 0.407 0.000
J45.9 Asthma, unspecified
0.591 0.409 0.000
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere
0.590 0.410 0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere
0.590 0.410 0.000
Z82.2 Family history of deafness and hearing loss
0.589 0.410 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.589 0.411 0.000
F61 Mixed and other personality disorders
0.587 0.412 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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