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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs709400
log Bayes Factor = 0.89509
Chromosome 14   position 104,149,475  (GRCh37) Explore rs709400 on Ensembl!
Variant rs709400 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Z72.1 Alcohol use
0.000 0.274 0.726
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.408 0.592 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.400 0.600 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.396 0.604 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.390 0.610 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.390 0.610 0.000
C83.3 Large cell (diffuse)
0.380 0.620 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.370 0.630 0.000
C90.0 Multiple myeloma
0.370 0.630 0.000
C92 Myeloid leukaemia
0.363 0.637 0.000
C90.2 Plasmacytoma, extramedullary
0.350 0.650 0.000
C85.1 B-cell lymphoma, unspecified
0.323 0.677 0.000
C88 Malignant immunoproliferative diseases
0.321 0.679 0.000
C92.1 Chronic myeloid leukaemia
0.318 0.682 0.000
C94 Other leukaemias of specified cell type
0.315 0.685 0.000
C90.3 Solitary plasmacytoma
0.309 0.691 0.000
C92.0 Acute myeloid leukaemia
0.302 0.698 0.000
C86 Other specified types of T/NK-cell lymphoma
0.294 0.706 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.291 0.709 0.000
C85.0 Lymphosarcoma
0.287 0.713 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.284 0.716 0.000
C92.7 Other myeloid leukaemia
0.284 0.716 0.000
C83.6 Undifferentiated (diffuse)
0.279 0.720 0.000
C83.5 Lymphoblastic (diffuse)
0.279 0.720 0.000
C83.4 Immunoblastic (diffuse)
0.279 0.720 0.000
C83.2 Mixed small and large cell (diffuse)
0.279 0.720 0.000
C93 Monocytic leukaemia
0.275 0.725 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.274 0.726 0.000
C90.1 Plasma cell leukaemia
0.273 0.727 0.000
C95 Leukaemia of unspecified cell type
0.268 0.732 0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.264 0.736 0.000
C92.9 Myeloid leukaemia, unspecified
0.260 0.740 0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.260 0.740 0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.260 0.740 0.000
C92.5 Acute myelomonocytic leukaemia
0.260 0.740 0.000
C92.3 Myeloid sarcoma
0.260 0.740 0.000
C92.2 Subacute myeloid leukaemia
0.260 0.740 0.000
C83.0 Small cell (diffuse)
0.259 0.741 0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.257 0.743 0.000
C92.4 Acute promyelocytic leukaemia
0.243 0.756 0.000
C88.0 Waldenstrom's macroglobulinaemia
0.236 0.764 0.000
C88.9 Malignant immunoproliferative disease, unspecified
0.230 0.770 0.000
C88.7 Other malignant immunoproliferative diseases
0.230 0.770 0.000
C88.3 Immunoproliferative small intestinal disease
0.230 0.770 0.000
C88.2 Gamma heavy chain disease
0.230 0.770 0.000
C88.1 Alpha heavy chain disease
0.230 0.770 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.228 0.772 0.000
C94.7 Other specified leukaemias
0.226 0.774 0.000
C94.5 Acute myelofibrosis
0.226 0.774 0.000
C94.4 Acute panmyelosis
0.226 0.774 0.000
C94.3 Mast cell leukaemia
0.226 0.774 0.000
C94.2 Acute megakaryoblastic leukaemia
0.226 0.774 0.000
C94.1 Chronic erythraemia
0.226 0.774 0.000
C94.0 Acute erythraemia and erythroleukaemia
0.226 0.774 0.000
C83.7 Burkitt's tumour
0.224 0.775 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.224 0.776 0.000
C86.5 Angioimmunoblastic T-cell lymphoma
0.221 0.779 0.000
C83.1 Small cleaved cell (diffuse)
0.215 0.785 0.000
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.211 0.789 0.000
C86.4 Blastic NK-cell lymphoma
0.211 0.789 0.000
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.211 0.789 0.000
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.211 0.789 0.000
C86.1 Hepatosplenic T-cell lymphoma
0.211 0.789 0.000
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.211 0.789 0.000
C81 Hodgkin's disease
0.207 0.793 0.000
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.204 0.796 0.000
C96.8 Histiocytic sarcoma
0.204 0.796 0.000
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.204 0.796 0.000
C96.6 Unifocal Langerhans-cell histiocytosis
0.204 0.796 0.000
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.204 0.796 0.000
C96.4 Sarcoma of dendritic cells (accessory cells)
0.204 0.796 0.000
C96.3 True histiocytic lymphoma
0.204 0.796 0.000
C96.2 Malignant mast cell tumour
0.204 0.796 0.000
C96.1 Malignant histiocytosis
0.204 0.796 0.000
C96.0 Letterer-Siwe disease
0.204 0.796 0.000
C93.9 Monocytic leukaemia, unspecified
0.197 0.802 0.000
C93.7 Other monocytic leukaemia
0.197 0.802 0.000
C93.3 Juvenile myelomonocytic leukaemia
0.197 0.802 0.000
C93.2 Subacute monocytic leukaemia
0.197 0.802 0.000
C93.0 Acute monocytic leukaemia
0.197 0.802 0.000
C95.7 Other leukaemia of unspecified cell type
0.192 0.808 0.000
C95.2 Subacute leukaemia of unspecified cell type
0.192 0.808 0.000
C95.1 Chronic leukaemia of unspecified cell type
0.192 0.808 0.000
C93.1 Chronic monocytic leukaemia
0.189 0.811 0.000
C95.9 Leukaemia, unspecified
0.188 0.811 0.000
C95.0 Acute leukaemia of unspecified cell type
0.180 0.819 0.000
C84.8 Cutaneous T-cell lymphoma, unspecified
0.167 0.833 0.000
C84.9 Mature T/NK-cell lymphoma, unspecified
0.161 0.839 0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.161 0.839 0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.161 0.839 0.000
C84.3 Lymphoepithelioid lymphoma
0.161 0.839 0.000
C84.2 T-zone lymphoma
0.161 0.839 0.000
C84.1 Sezary's diease
0.161 0.839 0.000
C84.0 Mycosis fungoides
0.160 0.840 0.000
C81.1 Nodular sclerosis
0.155 0.845 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.149 0.851 0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.149 0.851 0.000
C81.3 Lymphocytic depletion
0.149 0.851 0.000
C81.2 Mixed cellularity
0.146 0.853 0.000
C84.5 Other and unspecified T-cell lymphomas
0.140 0.860 0.000
C81.0 Lymphocytic predominance
0.140 0.860 0.000
C81.7 Other Hodgkin's disease
0.139 0.860 0.000
I10 Essential (primary) hypertension
0.000 0.862 0.138
C84.4 Peripheral T-cell lymphoma
0.123 0.877 0.000
C82.3 Follicular lymphoma grade IIIa
0.117 0.882 0.000
C91 Lymphoid leukaemia
0.109 0.891 0.000
C82.0 Small cleaved cell, follicular
0.107 0.893 0.000
C82.6 Cutaneous follicle centre lymphoma
0.107 0.893 0.000
C82.5 Diffuse follicle centre lymphoma
0.107 0.893 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.105 0.894 0.000
C82.4 Follicular lymphoma grade IIIb
0.101 0.898 0.000
C81.9 Hodgkin's disease, unspecified
0.097 0.903 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.094 0.906 0.000
C82.2 Large cell, follicular
0.089 0.910 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.910 0.090
C91.5 Adult T-cell leukaemia
0.086 0.914 0.000
I08 Multiple valve diseases
0.000 0.921 0.079
C91.8 Mature B-cell leukaemia Burkitt-type
0.078 0.922 0.000
C91.7 Other lymphoid leukaemia
0.078 0.922 0.000
C91.6 Prolymphocytic leukaemia of T-cell type
0.078 0.922 0.000
C91.3 Prolymphocytic leukaemia
0.078 0.922 0.000
C91.2 Subacute lymphocytic leukaemia
0.078 0.922 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.926 0.074
I08.0 Disorders of both mitral and aortic valves
0.000 0.930 0.070
C91.0 Acute lymphoblastic leukaemia
0.070 0.930 0.000
C91.4 Hairy-cell leukaemia
0.062 0.938 0.000
C91.9 Lymphoid leukaemia, unspecified
0.060 0.939 0.000
H80.9 Otosclerosis, unspecified
0.061 0.939 0.000
I10-I15 Hypertensive diseases
0.000 0.940 0.060
I05-I09 Chronic rheumatic heart diseases
0.000 0.944 0.056
Z72 Problems related to lifestyle
0.000 0.949 0.051
I08.9 Multiple valve disease, unspecified
0.000 0.952 0.048
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.952 0.048
I42.0 Dilated cardiomyopathy
0.000 0.953 0.047
I09 Other rheumatic heart diseases
0.000 0.954 0.046
I05 Rheumatic mitral valve diseases
0.000 0.955 0.045
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.043 0.957 0.000
F10.3 Withdrawal state
0.000 0.958 0.042
F10.4 Withdrawal state with delirium
0.000 0.958 0.042
Chapter IX Diseases of the circulatory system
0.000 0.958 0.042
F10 Mental and behavioural disorders due to use of alcohol
0.000 0.958 0.042
I13 Hypertensive heart and renal disease
0.000 0.959 0.041
I12 Hypertensive renal disease
0.000 0.959 0.041
F10.2 Dependence syndrome
0.000 0.960 0.040
I05.2 Mitral stenosis with insufficiency
0.000 0.960 0.040
I09.9 Rheumatic heart disease, unspecified
0.000 0.961 0.039
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.962 0.038
I05.9 Mitral valve disease, unspecified
0.000 0.963 0.037
Z72.9 Problem related to lifestyle, unspecified
0.000 0.963 0.037
I42 Cardiomyopathy
0.000 0.963 0.037
I15 Secondary hypertension
0.000 0.963 0.037
Z72.6 Gambling and betting
0.000 0.963 0.037
Z72.5 High-risk sexual behaviour
0.000 0.963 0.037
Z72.3 Lack of physical exercise
0.000 0.963 0.037
I74 Arterial embolism and thrombosis
0.000 0.965 0.035
I30-I52 Other forms of heart disease
0.000 0.965 0.035
I33 Acute and subacute endocarditis
0.000 0.965 0.035
I38 Endocarditis, valve unspecified
0.000 0.965 0.035
I33.0 Acute and subacute infective endocarditis
0.000 0.966 0.034
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.000 0.966 0.034
I42.9 Cardiomyopathy, unspecified
0.000 0.966 0.034
F17 Mental and behavioural disorders due to use of tobacco
0.000 0.967 0.033
I09.8 Other specified rheumatic heart diseases
0.000 0.967 0.033
I09.2 Chronic rheumatic pericarditis
0.000 0.967 0.033
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.967 0.033
I09.0 Rheumatic myocarditis
0.000 0.967 0.033
K70.3 Alcoholic cirrhosis of liver
0.000 0.967 0.033
I06 Rheumatic aortic valve diseases
0.000 0.967 0.033
I78 Diseases of capillaries
0.000 0.967 0.033
I11 Hypertensive heart disease
0.000 0.967 0.033
I50 Heart failure
0.000 0.967 0.033
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.967 0.033
I08.8 Other multiple valve diseases
0.000 0.968 0.032
I45 Other conduction disorders
0.000 0.968 0.032
F10.6 Amnesic syndrome
0.000 0.968 0.032
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.969 0.031
I70 Atherosclerosis
0.000 0.969 0.031
F17.2 Dependence syndrome
0.000 0.969 0.031
F10.5 Psychotic disorder
0.000 0.969 0.031
Z72.8 Other problems related to lifestyle
0.000 0.969 0.030
I50.0 Congestive heart failure
0.000 0.970 0.030
F17.1 Harmful use
0.000 0.970 0.030
I36 Nonrheumatic tricuspid valve disorders
0.000 0.970 0.030
F10.8 Other mental and behavioural disorders
0.000 0.970 0.030
Z72.4 Inappropriate diet and eating habits
0.000 0.970 0.030
I12.0 Hypertensive renal disease with renal failure
0.000 0.970 0.030
F10.7 Residual and late-onset psychotic disorder
0.000 0.970 0.030
K70.9 Alcoholic liver disease, unspecified
0.000 0.970 0.030
I15.0 Renovascular hypertension
0.000 0.970 0.030
K70 Alcoholic liver disease
0.000 0.970 0.030
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.970 0.029
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.970 0.029
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.970 0.029
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.970 0.030
I45.6 Preexcitation syndrome
0.000 0.970 0.030
I05.8 Other mitral valve diseases
0.000 0.970 0.029
F11 Mental and behavioural disorders due to use of opioids
0.000 0.971 0.029
I05.0 Mitral stenosis
0.000 0.971 0.029
I50.9 Heart failure, unspecified
0.000 0.971 0.029
I00-I02 Acute rheumatic fever
0.000 0.971 0.029
I72 Other aneurysm
0.000 0.971 0.029
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.971 0.029
H80 Otosclerosis
0.028 0.972 0.000
I74.5 Embolism and thrombosis of iliac artery
0.000 0.972 0.028
I78.1 Naevus, nonneoplastic
0.000 0.972 0.028
I71 Aortic aneurysm and dissection
0.000 0.972 0.028
I33.9 Acute endocarditis, unspecified
0.000 0.972 0.028
N39.0 Urinary tract infection, site not specified
0.000 0.972 0.028
I70.0 Atherosclerosis of aorta
0.000 0.972 0.028
I45.8 Other specified conduction disorders
0.000 0.973 0.027
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.973 0.027
I05.1 Rheumatic mitral insufficiency
0.000 0.973 0.027
I07 Rheumatic tricuspid valve diseases
0.000 0.973 0.027
I42.4 Endocardial fibroelastosis
0.000 0.973 0.027
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.973 0.027
I15.8 Other secondary hypertension
0.000 0.973 0.027
I15.2 Hypertension secondary to endocrine disorders
0.000 0.973 0.027
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.973 0.027
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.973 0.027
O66.5 Failed application of vacuum extractor and forceps, unspecified
0.026 0.974 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.974 0.026
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.974 0.026
L03.3 Cellulitis of trunk
0.000 0.974 0.026
I45.2 Bifascicular block
0.000 0.974 0.026
I12.9 Hypertensive renal disease without renal failure
0.000 0.974 0.026
I45.3 Trifascicular block
0.000 0.974 0.026
I42.6 Alcoholic cardiomyopathy
0.000 0.974 0.026
I45.9 Conduction disorder, unspecified
0.000 0.974 0.026
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.974 0.026
I52 Other heart disorders in diseases classified elsewhere
0.000 0.975 0.025
I48 Atrial fibrillation and flutter
0.000 0.975 0.025
I41 Myocarditis in diseases classified elsewhere
0.000 0.975 0.025
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.975 0.025
I32 Pericarditis in diseases classified elsewhere
0.000 0.975 0.025
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.975 0.025
I70.1 Atherosclerosis of renal artery
0.000 0.975 0.025
I72.2 Aneurysm of renal artery
0.000 0.975 0.025
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.000 0.975 0.025
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.975 0.025
K70.1 Alcoholic hepatitis
0.000 0.975 0.025
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.975 0.025
F18 Mental and behavioural disorders due to use of volatile solvents
0.000 0.975 0.025
F16 Mental and behavioural disorders due to use of hallucinogens
0.000 0.975 0.025
F14 Mental and behavioural disorders due to use of cocaine
0.000 0.975 0.025
I72.4 Aneurysm of artery of lower extremity
0.000 0.975 0.025
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.000 0.975 0.025
Z72.2 Drug use
0.000 0.976 0.024
I42.5 Other restrictive cardiomyopathy
0.000 0.976 0.024
F11.2 Dependence syndrome
0.000 0.976 0.024
F17.8 Other mental and behavioural disorders
0.000 0.976 0.024
F17.7 Residual and late-onset psychotic disorder
0.000 0.976 0.024
F17.6 Amnesic syndrome
0.000 0.976 0.024
F17.5 Psychotic disorder
0.000 0.976 0.024
F17.4 Withdrawal state with delirium
0.000 0.976 0.024
F17.0 Acute intoxication
0.000 0.976 0.024
I40 Acute myocarditis
0.000 0.976 0.024
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.976 0.024
I42.8 Other cardiomyopathies
0.000 0.976 0.024
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.976 0.024
I06.8 Other rheumatic aortic valve diseases
0.000 0.976 0.024
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.976 0.024
I78.9 Disease of capillaries, unspecified
0.000 0.976 0.024
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.976 0.023
I79.1 Aortitis in diseases classified elsewhere
0.000 0.976 0.023
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.976 0.023
F17.9 Unspecified mental and behavioural disorder
0.000 0.976 0.023
I15.1 Hypertension secondary to other renal disorders
0.000 0.976 0.023
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.977 0.023
F11.3 Withdrawal state
0.000 0.977 0.023
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.000 0.977 0.023
I70.8 Atherosclerosis of other arteries
0.000 0.977 0.023
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.977 0.022
F17.3 Withdrawal state
0.000 0.977 0.022
I45.0 Right fascicular block
0.000 0.977 0.022
F11.1 Harmful use
0.000 0.977 0.022
I78.8 Other diseases of capillaries
0.000 0.977 0.022
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.978 0.022
F10.9 Unspecified mental and behavioural disorder
0.000 0.978 0.022
K70.2 Alcoholic fibrosis and sclerosis of liver
0.000 0.978 0.022
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.978 0.022
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.978 0.022
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.978 0.022
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.978 0.022
I70.9 Generalised and unspecified atherosclerosis
0.000 0.978 0.021
F11.9 Unspecified mental and behavioural disorder
0.000 0.979 0.021
F11.8 Other mental and behavioural disorders
0.000 0.979 0.021
F11.7 Residual and late-onset psychotic disorder
0.000 0.979 0.021
F11.6 Amnesic syndrome
0.000 0.979 0.021
F11.5 Psychotic disorder
0.000 0.979 0.021
F11.4 Withdrawal state with delirium
0.000 0.979 0.021
F11.0 Acute intoxication
0.000 0.979 0.021
I72.3 Aneurysm of iliac artery
0.000 0.979 0.021
I06.1 Rheumatic aortic insufficiency
0.000 0.979 0.021
I72.0 Aneurysm of carotid artery
0.000 0.979 0.021
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.979 0.021
I42.2 Other hypertrophic cardiomyopathy
0.000 0.979 0.021
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.979 0.021
I37 Pulmonary valve disorders
0.000 0.979 0.021
F12 Mental and behavioural disorders due to use of cannabinoids
0.000 0.979 0.021
I02 Rheumatic chorea
0.000 0.979 0.021
I01 Rheumatic fever with heart involvement
0.000 0.979 0.021
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.979 0.021
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.979 0.021
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.979 0.021
H80.8 Other otosclerosis
0.020 0.979 0.000
H80.2 Cochlear otosclerosis
0.020 0.979 0.000
H80.1 Otosclerosis involving oval window, obliterative
0.020 0.979 0.000
H80.0 Otosclerosis involving oval window, nonobliterative
0.020 0.979 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.979 0.021
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.980 0.020
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.980 0.020
I51 Complications and ill-defined descriptions of heart disease
0.000 0.980 0.020
F10.1 Harmful use
0.000 0.980 0.020
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.980 0.020
I06.0 Rheumatic aortic stenosis
0.000 0.980 0.020
I71.0 Dissection of aorta [any part]
0.000 0.980 0.020
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.980 0.020
I07.9 Tricuspid valve disease, unspecified
0.000 0.980 0.019
I07.8 Other tricuspid valve diseases
0.000 0.980 0.019
I07.2 Tricuspid stenosis with insufficiency
0.000 0.980 0.019
I07.0 Tricuspid stenosis
0.000 0.980 0.019
I00 Rheumatic fever without mention of heart involvement
0.000 0.981 0.019
I45.4 Nonspecific intraventricular block
0.000 0.981 0.019
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.981 0.019
I15.9 Seconday hypertension, unspecified
0.000 0.981 0.019
K70.0 Alcoholic fatty liver
0.000 0.981 0.019
K70.4 Alcoholic hepatic failure
0.000 0.981 0.019
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.982 0.018
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.982 0.018
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.982 0.018
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.982 0.018
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.982 0.018
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.982 0.018
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.982 0.018
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.982 0.018
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.982 0.018
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.982 0.018
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.982 0.018
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.982 0.018
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.982 0.018
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.982 0.018
I48.4 Atypical atrial flutter
0.000 0.982 0.018
I48.3 Typical atrial flutter
0.000 0.982 0.018
I48.2 Chronic atrial fibrillation
0.000 0.982 0.018
I48.1 Persistent atrial fibrillation
0.000 0.982 0.018
I48.0 Paroxysmal atrial fibrillation
0.000 0.982 0.018
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.982 0.018
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.982 0.018
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.982 0.018
I72.8 Aneurysm of other specified arteries
0.000 0.982 0.018
F13.2 Dependence syndrome
0.000 0.982 0.018
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.982 0.018
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.982 0.018
F19.2 Dependence syndrome
0.000 0.982 0.018
F13.9 Unspecified mental and behavioural disorder
0.000 0.982 0.018
F13.8 Other mental and behavioural disorders
0.000 0.982 0.018
F13.7 Residual and late-onset psychotic disorder
0.000 0.982 0.018
F13.6 Amnesic syndrome
0.000 0.982 0.018
F13.5 Psychotic disorder
0.000 0.982 0.018
F13.4 Withdrawal state with delirium
0.000 0.982 0.018
F13.3 Withdrawal state
0.000 0.982 0.018
F13.1 Harmful use
0.000 0.982 0.018
F13.0 Acute intoxication
0.000 0.982 0.018
F14.9 Unspecified mental and behavioural disorder
0.000 0.982 0.018
F14.8 Other mental and behavioural disorders
0.000 0.982 0.018
F14.7 Residual and late-onset psychotic disorder
0.000 0.982 0.018
F14.6 Amnesic syndrome
0.000 0.982 0.018
F14.5 Psychotic disorder
0.000 0.982 0.018
F14.4 Withdrawal state with delirium
0.000 0.982 0.018
F14.3 Withdrawal state
0.000 0.982 0.018
F14.2 Dependence syndrome
0.000 0.982 0.018
F14.1 Harmful use
0.000 0.982 0.018
F14.0 Acute intoxication
0.000 0.982 0.018
F16.9 Unspecified mental and behavioural disorder
0.000 0.982 0.018
F16.8 Other mental and behavioural disorders
0.000 0.982 0.018
F16.7 Residual and late-onset psychotic disorder
0.000 0.982 0.018
F16.6 Amnesic syndrome
0.000 0.982 0.018
F16.5 Psychotic disorder
0.000 0.982 0.018
F16.4 Withdrawal state with delirium
0.000 0.982 0.018
F16.3 Withdrawal state
0.000 0.982 0.018
F16.2 Dependence syndrome
0.000 0.982 0.018
F16.1 Harmful use
0.000 0.982 0.018
F16.0 Acute intoxication
0.000 0.982 0.018
F18.9 Unspecified mental and behavioural disorder
0.000 0.982 0.018
F18.8 Other mental and behavioural disorders
0.000 0.982 0.018
F18.7 Residual and late-onset psychotic disorder
0.000 0.982 0.018
F18.6 Amnesic syndrome
0.000 0.982 0.018
F18.5 Psychotic disorder
0.000 0.982 0.018
F18.4 Withdrawal state with delirium
0.000 0.982 0.018
F18.3 Withdrawal state
0.000 0.982 0.018
F18.2 Dependence syndrome
0.000 0.982 0.018
F18.1 Harmful use
0.000 0.982 0.018
F18.0 Acute intoxication
0.000 0.982 0.018
I74.8 Embolism and thrombosis of other arteries
0.000 0.982 0.018
F19.9 Unspecified mental and behavioural disorder
0.000 0.982 0.018
F19.8 Other mental and behavioural disorders
0.000 0.982 0.018
F19.7 Residual and late-onset psychotic disorder
0.000 0.982 0.018
F19.6 Amnesic syndrome
0.000 0.982 0.018
F19.5 Psychotic disorder
0.000 0.982 0.018
F19.4 Withdrawal state with delirium
0.000 0.982 0.018
F19.3 Withdrawal state
0.000 0.982 0.018
F19.0 Acute intoxication
0.000 0.982 0.018
I40.9 Acute myocarditis, unspecified
0.000 0.982 0.018
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.982 0.018
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.982 0.017
I40.8 Other acute myocarditis
0.000 0.982 0.017
I40.1 Isolated myocarditis
0.000 0.982 0.017
I34 Nonrheumatic mitral valve disorders
0.000 0.982 0.018
F19.1 Harmful use
0.000 0.983 0.017
C91.1 Chronic lymphocytic leukaemia
0.017 0.983 0.000
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.983 0.017
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.983 0.017
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.983 0.017
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.983 0.017
F15.9 Unspecified mental and behavioural disorder
0.000 0.983 0.017
F15.8 Other mental and behavioural disorders
0.000 0.983 0.017
F15.7 Residual and late-onset psychotic disorder
0.000 0.983 0.017
F15.6 Amnesic syndrome
0.000 0.983 0.017
F15.5 Psychotic disorder
0.000 0.983 0.017
F15.4 Withdrawal state with delirium
0.000 0.983 0.017
F15.3 Withdrawal state
0.000 0.983 0.017
F15.2 Dependence syndrome
0.000 0.983 0.017
F15.0 Acute intoxication
0.000 0.983 0.017
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.983 0.017
I45.1 Other and unspecified right bundle-branch block
0.000 0.983 0.017
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.983 0.016
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.983 0.016
I50.1 Left ventricular failure
0.000 0.983 0.017
I62 Other nontraumatic intracranial haemorrhage
0.000 0.984 0.016
J91 Pleural effusion in conditions classified elsewhere
0.000 0.984 0.016
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.984 0.016
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.984 0.016
I40.0 Infective myocarditis
0.000 0.984 0.016
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.984 0.016
I51.7 Cardiomegaly
0.000 0.984 0.016
I51.6 Cardiovascular disease, unspecified
0.000 0.985 0.015
I72.1 Aneurysm of artery of upper extremity
0.000 0.985 0.015
I37.9 Pulmonary valve disorder, unspecified
0.000 0.985 0.015
I37.8 Other pulmonary valve disorders
0.000 0.985 0.015
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.985 0.015
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.985 0.015
F12.9 Unspecified mental and behavioural disorder
0.000 0.985 0.015
F12.8 Other mental and behavioural disorders
0.000 0.985 0.015
F12.7 Residual and late-onset psychotic disorder
0.000 0.985 0.015
F12.6 Amnesic syndrome
0.000 0.985 0.015
F12.5 Psychotic disorder
0.000 0.985 0.015
F12.4 Withdrawal state with delirium
0.000 0.985 0.015
F12.3 Withdrawal state
0.000 0.985 0.015
F12.0 Acute intoxication
0.000 0.985 0.015
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.985 0.015
I01.8 Other acute rheumatic heart disease
0.000 0.985 0.015
I01.2 Acute rheumatic myocarditis
0.000 0.985 0.015
I01.1 Acute rheumatic endocarditis
0.000 0.985 0.015
I01.0 Acute rheumatic pericarditis
0.000 0.985 0.015
I02.9 Rheumatic chorea without heart involvement
0.000 0.985 0.015
I02.0 Rheumatic chorea with heart involvement
0.000 0.985 0.015
F15.1 Harmful use
0.000 0.985 0.015
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.985 0.015
I72.9 Aneurysm of unspecified site
0.000 0.985 0.015
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.985 0.015
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.985 0.015
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.985 0.015
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.985 0.015
F12.1 Harmful use
0.000 0.985 0.015
I51.5 Myocardial degeneration
0.000 0.985 0.015
I77 Other disorders of arteries and arterioles
0.000 0.985 0.015
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.986 0.014
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.986 0.014
I98.0 Cardiovascular syphilis
0.000 0.986 0.014
I30 Acute pericarditis
0.000 0.986 0.014
I37.0 Pulmonary valve stenosis
0.000 0.986 0.014
Z72.0 Tobacco use
0.000 0.986 0.014
I60-I69 Cerebrovascular diseases
0.000 0.986 0.014
O66 Other obstructed labour
0.014 0.986 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.987 0.013
I31 Other diseases of pericardium
0.000 0.987 0.013
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.987 0.013
I37.1 Pulmonary valve insufficiency
0.000 0.987 0.013
I45.5 Other specified heart block
0.000 0.987 0.013
I62.1 Nontraumatic extradural haemorrhage
0.000 0.987 0.013
K74.3 Primary biliary cirrhosis
0.000 0.988 0.012
F12.2 Dependence syndrome
0.000 0.988 0.012
I51.4 Myocarditis, unspecified
0.000 0.988 0.012
I34.0 Mitral (valve) insufficiency
0.000 0.988 0.012
I73 Other peripheral vascular diseases
0.000 0.988 0.012
I77.2 Rupture of artery
0.000 0.988 0.012
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.989 0.011
I51.9 Heart disease, unspecified
0.000 0.989 0.011
R47.0 Dysphasia and aphasia
0.000 0.989 0.011
K74 Fibrosis and cirrhosis of liver
0.000 0.989 0.011
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.989 0.011
I51.8 Other ill-defined heart diseases
0.000 0.989 0.011
I46 Cardiac arrest
0.000 0.989 0.011
J90-J94 Other diseases of pleura
0.000 0.989 0.011
I51.0 Cardiac septal defect, acquired
0.000 0.989 0.011
I77.5 Necrosis of artery
0.000 0.989 0.011
I77.4 Coeliac artery compression syndrome
0.000 0.989 0.011
I77.3 Arterial fibromuscular dysplasia
0.000 0.989 0.011
I31.3 Pericardial effusion (noninflammatory)
0.000 0.989 0.011
I77.1 Stricture of artery
0.000 0.989 0.011

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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