TreeWAS – Variant ID: rs7107174

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M20.1 Hallux valgus (acquired)	0.000	0.022	0.978
F10 Mental and behavioural disorders due to use of alcohol	0.977	0.023	0.000
F10.2 Dependence syndrome	0.971	0.029	0.000
F10.1 Harmful use	0.969	0.031	0.000
M20 Acquired deformities of fingers and toes	0.000	0.032	0.968
F10.3 Withdrawal state	0.955	0.045	0.000
M20.5 Other deformities of toe(s) (acquired)	0.000	0.046	0.954
F10.0 Acute intoxication	0.948	0.052	0.000
M20.2 Hallux rigidus	0.000	0.056	0.944
M20.6 Acquired deformity of toe(s), unspecified	0.000	0.156	0.844
F10.5 Psychotic disorder	0.787	0.213	0.000
F10.9 Unspecified mental and behavioural disorder	0.775	0.225	0.000
F10.8 Other mental and behavioural disorders	0.701	0.299	0.000
F10.7 Residual and late-onset psychotic disorder	0.701	0.299	0.000
F10.4 Withdrawal state with delirium	0.686	0.314	0.000
M20.3 Other deformity of hallux (acquired)	0.000	0.377	0.622
F10.6 Amnesic syndrome	0.598	0.401	0.000
M20.0 Deformity of finger(s)	0.000	0.452	0.548
M20.4 Other hammer toe(s) (acquired)	0.000	0.537	0.463
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.228	0.772	0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.182	0.818	0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.173	0.827	0.000
F18 Mental and behavioural disorders due to use of volatile solvents	0.164	0.836	0.000
F16 Mental and behavioural disorders due to use of hallucinogens	0.164	0.836	0.000
F14 Mental and behavioural disorders due to use of cocaine	0.164	0.836	0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.164	0.836	0.000
F11 Mental and behavioural disorders due to use of opioids	0.155	0.845	0.000
F12 Mental and behavioural disorders due to use of cannabinoids	0.149	0.851	0.000
F15.1 Harmful use	0.149	0.851	0.000
F19.1 Harmful use	0.133	0.866	0.000
F15.9 Unspecified mental and behavioural disorder	0.130	0.869	0.000
F15.8 Other mental and behavioural disorders	0.130	0.869	0.000
F15.7 Residual and late-onset psychotic disorder	0.130	0.869	0.000
F15.6 Amnesic syndrome	0.130	0.869	0.000
F15.5 Psychotic disorder	0.130	0.869	0.000
F15.4 Withdrawal state with delirium	0.130	0.869	0.000
F15.3 Withdrawal state	0.130	0.869	0.000
F15.2 Dependence syndrome	0.130	0.869	0.000
F15.0 Acute intoxication	0.130	0.869	0.000
F19.9 Unspecified mental and behavioural disorder	0.124	0.876	0.000
F19.8 Other mental and behavioural disorders	0.124	0.876	0.000
F19.7 Residual and late-onset psychotic disorder	0.124	0.876	0.000
F19.6 Amnesic syndrome	0.124	0.876	0.000
F19.5 Psychotic disorder	0.124	0.876	0.000
F19.4 Withdrawal state with delirium	0.124	0.876	0.000
F19.3 Withdrawal state	0.124	0.876	0.000
F19.0 Acute intoxication	0.124	0.876	0.000
F19.2 Dependence syndrome	0.123	0.876	0.000
F13.9 Unspecified mental and behavioural disorder	0.118	0.882	0.000
F13.8 Other mental and behavioural disorders	0.118	0.882	0.000
F13.7 Residual and late-onset psychotic disorder	0.118	0.882	0.000
F13.6 Amnesic syndrome	0.118	0.882	0.000
F13.5 Psychotic disorder	0.118	0.882	0.000
F13.4 Withdrawal state with delirium	0.118	0.882	0.000
F13.3 Withdrawal state	0.118	0.882	0.000
F13.2 Dependence syndrome	0.118	0.882	0.000
F13.1 Harmful use	0.118	0.882	0.000
F13.0 Acute intoxication	0.118	0.882	0.000
F14.9 Unspecified mental and behavioural disorder	0.118	0.882	0.000
F14.8 Other mental and behavioural disorders	0.118	0.882	0.000
F14.7 Residual and late-onset psychotic disorder	0.118	0.882	0.000
F14.6 Amnesic syndrome	0.118	0.882	0.000
F14.5 Psychotic disorder	0.118	0.882	0.000
F14.4 Withdrawal state with delirium	0.118	0.882	0.000
F14.3 Withdrawal state	0.118	0.882	0.000
F14.2 Dependence syndrome	0.118	0.882	0.000
F14.1 Harmful use	0.118	0.882	0.000
F14.0 Acute intoxication	0.118	0.882	0.000
F16.9 Unspecified mental and behavioural disorder	0.118	0.882	0.000
F16.8 Other mental and behavioural disorders	0.118	0.882	0.000
F16.7 Residual and late-onset psychotic disorder	0.118	0.882	0.000
F16.6 Amnesic syndrome	0.118	0.882	0.000
F16.5 Psychotic disorder	0.118	0.882	0.000
F16.4 Withdrawal state with delirium	0.118	0.882	0.000
F16.3 Withdrawal state	0.118	0.882	0.000
F16.2 Dependence syndrome	0.118	0.882	0.000
F16.1 Harmful use	0.118	0.882	0.000
F16.0 Acute intoxication	0.118	0.882	0.000
F18.9 Unspecified mental and behavioural disorder	0.118	0.882	0.000
F18.8 Other mental and behavioural disorders	0.118	0.882	0.000
F18.7 Residual and late-onset psychotic disorder	0.118	0.882	0.000
F18.6 Amnesic syndrome	0.118	0.882	0.000
F18.5 Psychotic disorder	0.118	0.882	0.000
F18.4 Withdrawal state with delirium	0.118	0.882	0.000
F18.3 Withdrawal state	0.118	0.882	0.000
F18.2 Dependence syndrome	0.118	0.882	0.000
F18.1 Harmful use	0.118	0.882	0.000
F18.0 Acute intoxication	0.118	0.882	0.000
F11.9 Unspecified mental and behavioural disorder	0.111	0.889	0.000
F11.8 Other mental and behavioural disorders	0.111	0.889	0.000
F11.7 Residual and late-onset psychotic disorder	0.111	0.889	0.000
F11.6 Amnesic syndrome	0.111	0.889	0.000
F11.5 Psychotic disorder	0.111	0.889	0.000
F11.4 Withdrawal state with delirium	0.111	0.889	0.000
F11.3 Withdrawal state	0.111	0.889	0.000
F11.0 Acute intoxication	0.111	0.889	0.000
F11.1 Harmful use	0.109	0.891	0.000
F12.9 Unspecified mental and behavioural disorder	0.107	0.893	0.000
F12.8 Other mental and behavioural disorders	0.107	0.893	0.000
F12.7 Residual and late-onset psychotic disorder	0.107	0.893	0.000
F12.6 Amnesic syndrome	0.107	0.893	0.000
F12.5 Psychotic disorder	0.107	0.893	0.000
F12.4 Withdrawal state with delirium	0.107	0.893	0.000
F12.3 Withdrawal state	0.107	0.893	0.000
F12.0 Acute intoxication	0.107	0.893	0.000
F11.2 Dependence syndrome	0.104	0.896	0.000
F12.1 Harmful use	0.103	0.897	0.000
F12.2 Dependence syndrome	0.097	0.903	0.000
D70 Agranulocytosis	0.082	0.918	0.000
D73.0 Hyposplenism	0.077	0.923	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.077	0.923	0.000
D73 Diseases of spleen	0.076	0.924	0.000
S06 Intracranial injury	0.076	0.924	0.000
N95.8 Other specified menopausal and perimenopausal disorders	0.076	0.924	0.000
S06.2 Diffuse brain injury	0.074	0.926	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.073	0.927	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.073	0.927	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.071	0.929	0.000
S00-S09 Injuries to the head	0.067	0.933	0.000
S06.3 Focal brain injury	0.065	0.935	0.000
D73.9 Disease of spleen, unspecified	0.064	0.936	0.000
S06.0 Concussion	0.063	0.936	0.000
S01 Open wound of head	0.063	0.937	0.000
D72 Other disorders of white blood cells	0.061	0.939	0.000
S01.5 Open wound of lip and oral cavity	0.061	0.939	0.000
S02 Fracture of skull and facial bones	0.059	0.941	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.056	0.943	0.000
S06.8 Other intracranial injuries	0.056	0.944	0.000
S06.5 Traumatic subdural haemorrhage	0.056	0.944	0.000
D74 Methaemoglobinaemia	0.055	0.945	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.055	0.945	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.055	0.945	0.000
D73.4 Cyst of spleen	0.055	0.945	0.000
D73.3 Abscess of spleen	0.055	0.945	0.000
D73.2 Chronic congestive splenomegaly	0.055	0.945	0.000
D73.1 Hypersplenism	0.055	0.945	0.000
S01.4 Open wound of cheek and temporomandibular area	0.055	0.945	0.000
S06.7 Intracranial injury with prolonged coma	0.055	0.945	0.000
S06.1 Traumatic cerebral oedema	0.055	0.945	0.000
S02.1 Fracture of base of skull	0.055	0.945	0.000
S06.00 Concussion (without open intracranial wound)	0.055	0.945	0.000
S05 Injury of eye and orbit	0.054	0.946	0.000
S01.8 Open wound of other parts of head	0.054	0.946	0.000
N93.8 Other specified abnormal uterine and vaginal bleeding	0.053	0.947	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.053	0.947	0.000
S06.4 Epidural haemorrhage	0.053	0.947	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.052	0.947	0.000
F17 Mental and behavioural disorders due to use of tobacco	0.052	0.948	0.000
S02.10 Fracture of base of skull (closed)	0.052	0.948	0.000
S02.0 Fracture of vault of skull	0.051	0.949	0.000
D73.8 Other diseases of spleen	0.050	0.949	0.000
S01.0 Open wound of scalp	0.050	0.949	0.000
D73.5 Infarction of spleen	0.050	0.950	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.050	0.950	0.000
D72.8 Other specified disorders of white blood cells	0.050	0.950	0.000
S00 Superficial injury of head	0.049	0.951	0.000
S05.1 Contusion of eyeball and orbital tissues	0.048	0.952	0.000
S08 Traumatic amputation of part of head	0.048	0.952	0.000
S07 Crushing injury of head	0.048	0.952	0.000
S04 Injury of cranial nerves	0.048	0.952	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.048	0.952	0.000
S06.9 Intracranial injury, unspecified	0.047	0.953	0.000
S06.31 Focal brain injury (with open intracranial wound)	0.046	0.953	0.000
S00.7 Multiple superficial injuries of head	0.046	0.954	0.000
S06.01 Concussion (with open intracranial wound)	0.046	0.954	0.000
D72.1 Eosinophilia	0.046	0.954	0.000
S02.6 Fracture of mandible	0.045	0.955	0.000
S02.7 Multiple fractures involving skull and facial bones	0.045	0.955	0.000
S02.00 Fracture of vault of skull (closed)	0.045	0.955	0.000
D72.9 Disorder of white blood cells, unspecified	0.044	0.956	0.000
D72.0 Genetic anomalies of leukocytes	0.044	0.956	0.000
S02.4 Fracture of malar and maxillary bones	0.044	0.956	0.000
S02.8 Fractures of other skull and facial bones	0.043	0.957	0.000
S01.1 Open wound of eyelid and periocular area	0.043	0.957	0.000
S01.3 Open wound of ear	0.043	0.957	0.000
S01.2 Open wound of nose	0.043	0.957	0.000
D75 Other diseases of blood and blood-forming organs	0.042	0.957	0.000
S00.5 Superficial injury of lip and oral cavity	0.042	0.958	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.042	0.958	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.042	0.958	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.041	0.959	0.000
S02.3 Fracture of orbital floor	0.041	0.959	0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.041	0.959	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.040	0.959	0.000
S06.81 Other intracranial injuries (with open intracranial wound)	0.040	0.959	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.040	0.960	0.000
D74.9 Methaemoglobinaemia, unspecified	0.040	0.960	0.000
D74.8 Other methaemoglobinaemias	0.040	0.960	0.000
D74.0 Congenital methaemoglobinaemia	0.040	0.960	0.000
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.039	0.960	0.000
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.039	0.960	0.000
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.039	0.960	0.000
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.039	0.960	0.000
D80-D89 Certain disorders involving the immune mechanism	0.040	0.960	0.000
S02.11 Fracture of base of skull (open)	0.039	0.960	0.000
S05.7 Avulsion of eye	0.039	0.961	0.000
S05.6 Penetrating wound of eyeball without foreign body	0.039	0.961	0.000
S05.5 Penetrating wound of eyeball with foreign body	0.039	0.961	0.000
S05.4 Penetrating wound of orbit with or without foreign body	0.039	0.961	0.000
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.039	0.961	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.039	0.961	0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.038	0.962	0.000
S06.41 Epidural haemorrhage (with open intracranial wound)	0.038	0.962	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.038	0.962	0.000
F17.9 Unspecified mental and behavioural disorder	0.038	0.962	0.000
F17.8 Other mental and behavioural disorders	0.038	0.962	0.000
F17.7 Residual and late-onset psychotic disorder	0.038	0.962	0.000
F17.6 Amnesic syndrome	0.038	0.962	0.000
F17.5 Psychotic disorder	0.038	0.962	0.000
F17.4 Withdrawal state with delirium	0.038	0.962	0.000
F17.3 Withdrawal state	0.038	0.962	0.000
F17.0 Acute intoxication	0.038	0.962	0.000
S02.5 Fracture of tooth	0.037	0.963	0.000
S02.01 Fracture of vault of skull (open)	0.037	0.963	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.037	0.963	0.000
D69.6 Thrombocytopenia, unspecified	0.037	0.963	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.036	0.964	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.036	0.964	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.036	0.964	0.000
D76.2 Haemophagocytic syndrome, infection-associated	0.036	0.964	0.000
D76.1 Haemophagocytic lymphohistiocytosis	0.036	0.964	0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.036	0.964	0.000
S00.3 Superficial injury of nose	0.036	0.964	0.000
D69 Purpura and other haemorrhagic conditions	0.036	0.964	0.000
S05.8 Other injuries of eye and orbit	0.036	0.964	0.000
S02.60 Fracture of mandible (closed)	0.035	0.965	0.000
S02.70 Multiple fractures involving skull and facial bones (closed)	0.035	0.965	0.000
D75.0 Familial erythrocytosis	0.035	0.965	0.000
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head	0.035	0.965	0.000
S03.4 Sprain and strain of jaw	0.035	0.965	0.000
S03.3 Dislocation of other and unspecified parts of head	0.035	0.965	0.000
S03.2 Dislocation of tooth	0.035	0.965	0.000
S03.1 Dislocation of septal cartilage of nose	0.035	0.965	0.000
S03.0 Dislocation of jaw	0.035	0.965	0.000
S04.9 Injury of unspecified cranial nerve	0.035	0.965	0.000
S04.8 Injury of other cranial nerves	0.035	0.965	0.000
S04.7 Injury of accessory nerve	0.035	0.965	0.000
S04.6 Injury of acoustic nerve	0.035	0.965	0.000
S04.5 Injury of facial nerve	0.035	0.965	0.000
S04.4 Injury of abducent nerve	0.035	0.965	0.000
S04.3 Injury of trigeminal nerve	0.035	0.965	0.000
S04.2 Injury of trochlear nerve	0.035	0.965	0.000
S04.1 Injury of oculomotor nerve	0.035	0.965	0.000
S04.0 Injury of optic nerve and pathways	0.035	0.965	0.000
S07.9 Crushing injury of head, part unspecified	0.035	0.965	0.000
S07.8 Crushing injury of other parts of head	0.035	0.965	0.000
S07.1 Crushing injury of skull	0.035	0.965	0.000
S07.0 Crushing injury of face	0.035	0.965	0.000
S08.9 Traumatic amputation of unspecified part of head	0.035	0.965	0.000
S08.8 Traumatic amputation of other parts of head	0.035	0.965	0.000
S08.1 Traumatic amputation of ear	0.035	0.965	0.000
S08.0 Avulsion of scalp	0.035	0.965	0.000
S05.9 Injury of eye and orbit, part unspecified	0.034	0.966	0.000
S00.4 Superficial injury of ear	0.034	0.966	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.034	0.966	0.000
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.034	0.966	0.000
S02.61 Fracture of mandible (open)	0.033	0.967	0.000
S02.71 Multiple fractures involving skull and facial bones (open)	0.033	0.967	0.000
S00.1 Contusion of eyelid and periocular area	0.032	0.968	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.032	0.968	0.000
S09 Other and unspecified injuries of head	0.032	0.968	0.000
S02.81 Fractures of other skull and facial bones (open)	0.031	0.969	0.000
S00.0 Superficial injury of scalp	0.031	0.969	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.031	0.969	0.000
D82 Immunodeficiency associated with other major defects	0.031	0.969	0.000
D76.3 Other histiocytosis syndromes	0.030	0.969	0.000
S00.2 Other superficial injuries of eyelid and periocular area	0.030	0.969	0.000
D69.5 Secondary thrombocytopenia	0.030	0.970	0.000
D55-D59 Haemolytic anaemias	0.030	0.970	0.000
S02.31 Fracture of orbital floor (open)	0.030	0.970	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.029	0.970	0.000
S02.2 Fracture of nasal bones	0.029	0.971	0.000
D83 Common variable immunodeficiency	0.029	0.971	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.029	0.971	0.000
D89.3 Immune reconstitution syndrome	0.029	0.971	0.000
D89.1 Cryoglobulinaemia	0.029	0.971	0.000
D81 Combined immunodeficiencies	0.029	0.971	0.000
D80 Immunodeficiency with predominantly antibody defects	0.029	0.971	0.000
S02.30 Fracture of orbital floor (closed)	0.028	0.972	0.000
S01.7 Multiple open wounds of head	0.027	0.972	0.000
D84 Other immunodeficiencies	0.028	0.972	0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.027	0.972	0.000
D69.9 Haemorrhagic condition, unspecified	0.027	0.972	0.000
D69.4 Other primary thrombocytopenia	0.027	0.973	0.000
S02.51 Fracture of tooth (open)	0.027	0.973	0.000
S00.8 Superficial injury of other parts of head	0.027	0.973	0.000
S00.9 Superficial injury of head, part unspecified	0.026	0.974	0.000
D69.2 Other nonthrombocytopenic purpura	0.026	0.974	0.000
D67 Hereditary factor IX deficiency	0.026	0.974	0.000
D69.8 Other specified haemorrhagic conditions	0.026	0.974	0.000
D69.1 Qualitative platelet defects	0.026	0.974	0.000
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.025	0.974	0.000
D69.0 Allergic purpura	0.026	0.974	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.025	0.975	0.000
S09.2 Traumatic rupture of ear drum	0.025	0.975	0.000
D66 Hereditary factor VIII deficiency	0.025	0.975	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.025	0.975	0.000
D58 Other hereditary haemolytic anaemias	0.025	0.975	0.000
S01.9 Open wound of head, part unspecified	0.024	0.975	0.000
D82.1 Di George's syndrome	0.024	0.976	0.000
S09.0 Injury of blood vessels of head, not elsewhere classified	0.023	0.977	0.000
S09.7 Multiple injuries of head	0.023	0.977	0.000
S09.1 Injury of muscle and tendon of head	0.023	0.977	0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.023	0.977	0.000
S09.8 Other specified injuries of head	0.022	0.977	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.022	0.978	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.022	0.978	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.022	0.978	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.022	0.978	0.000
D82.2 Immunodeficiency with short-limbed stature	0.022	0.978	0.000
D82.0 Wiskott-Aldrich syndrome	0.022	0.978	0.000
D75.2 Essential thrombocytosis	0.022	0.978	0.001
D57 Sickle-cell disorders	0.022	0.978	0.000
D55 Anaemia due to enzyme disorders	0.022	0.978	0.000
D56 Thalassaemia	0.021	0.979	0.000
D83.9 Common variable immunodeficiency, unspecified	0.021	0.979	0.000
S02.21 Fracture of nasal bones (open)	0.021	0.979	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.021	0.979	0.000
S02.50 Fracture of tooth (closed)	0.021	0.979	0.000
D83.8 Other common variable immunodeficiencies	0.021	0.979	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.021	0.979	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.021	0.979	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.021	0.979	0.000
D81.9 Combined immunodeficiency, unspecified	0.021	0.979	0.000
D81.8 Other combined immunodeficiencies	0.021	0.979	0.000
D81.7 Major histocompatibility complex class II deficiency	0.021	0.979	0.000
D81.6 Major histocompatibility complex class I deficiency	0.021	0.979	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.021	0.979	0.000
D81.4 Nezelof's syndrome	0.021	0.979	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.021	0.979	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.021	0.979	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.021	0.979	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.021	0.979	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.021	0.979	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.021	0.979	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.021	0.979	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.021	0.979	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.021	0.979	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.021	0.979	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.021	0.979	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.021	0.979	0.000
D86 Sarcoidosis	0.021	0.979	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.020	0.980	0.000
D84.8 Other specified immunodeficiencies	0.020	0.980	0.000
D84.1 Defects in the complement system	0.020	0.980	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.020	0.980	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.020	0.980	0.000
D58.0 Hereditary spherocytosis	0.019	0.980	0.000
D84.9 Immunodeficiency, unspecified	0.019	0.981	0.000
D59 Acquired haemolytic anaemia	0.018	0.981	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.018	0.982	0.000
D58.2 Other haemoglobinopathies	0.018	0.982	0.000
D58.1 Hereditary elliptocytosis	0.018	0.982	0.000
D86.1 Sarcoidosis of lymph nodes	0.017	0.983	0.000
F17.2 Dependence syndrome	0.016	0.984	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.016	0.984	0.000
D68 Other coagulation defects	0.016	0.984	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.016	0.984	0.000
D55.8 Other anaemias due to enzyme disorders	0.016	0.984	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.016	0.984	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.016	0.984	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.016	0.984	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.016	0.984	0.000
D57.8 Other sickle-cell disorders	0.016	0.984	0.000
D57.3 Sickle-cell trait	0.016	0.984	0.000
D57.2 Double heterozygous sickling disorders	0.016	0.984	0.000
D57.1 Sickle-cell anaemia without crisis	0.016	0.984	0.000
D57.0 Sickle-cell anaemia with crisis	0.016	0.984	0.000
D56.1 Beta thalassaemia	0.015	0.984	0.000
D56.9 Thalassaemia, unspecified	0.015	0.984	0.000
D56.8 Other thalassaemias	0.015	0.984	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.015	0.984	0.000
D56.2 Delta-beta thalassaemia	0.015	0.984	0.000
D56.0 Alpha thalassaemia	0.015	0.984	0.000
S42.20 Fracture of upper end of humerus (closed)	0.016	0.984	0.000
D86.3 Sarcoidosis of skin	0.015	0.985	0.000
D56.3 Thalassaemia trait	0.015	0.985	0.000
S42.2 Fracture of upper end of humerus	0.014	0.986	0.000
S42.10 Fracture of scapula (closed)	0.014	0.986	0.000
D68.8 Other specified coagulation defects	0.014	0.986	0.000
D59.8 Other acquired haemolytic anaemias	0.013	0.986	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.013	0.986	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.013	0.986	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.013	0.986	0.000
D59.3 Haemolytic-uraemic syndrome	0.013	0.986	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.013	0.986	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.013	0.986	0.000
S42.1 Fracture of scapula	0.013	0.987	0.000
S42 Fracture of shoulder and upper arm	0.013	0.987	0.000
D86.8 Sarcoidosis of other and combined sites	0.013	0.987	0.000
D68.1 Hereditary factor XI deficiency	0.013	0.987	0.000
D68.5 Primary Thrombophilia	0.013	0.987	0.000
D59.1 Other autoimmune haemolytic anaemias	0.012	0.987	0.000
D50-D53 Nutritional anaemias	0.012	0.988	0.000
D68.4 Acquired coagulation factor deficiency	0.012	0.988	0.000
D86.9 Sarcoidosis, unspecified	0.012	0.988	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.011	0.988	0.000
D68.0 Von Willebrand's disease	0.011	0.989	0.000
S42.9 Fracture of shoulder girdle, part unspecified	0.011	0.989	0.000
D60-D64 Aplastic and other anaemias	0.011	0.989	0.000
S42.4 Fracture of lower end of humerus	0.011	0.989	0.000
S42.21 Fracture of upper end of humerus (open)	0.010	0.990	0.000
S42.11 Fracture of scapula (open)	0.010	0.990	0.000
S42.8 Fracture of other parts of shoulder and upper arm	0.010	0.990	0.000
Z30.1 Insertion of (intra-uterine) contraceptive device	0.010	0.990	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.010	0.990	0.000
S40-S49 Injuries to the shoulder and upper arm	0.010	0.990	0.000
S42.3 Fracture of shaft of humerus	0.009	0.991	0.000
D68.9 Coagulation defect, unspecified	0.009	0.991	0.000
S42.0 Fracture of clavicle	0.009	0.991	0.000
D53 Other nutritional anaemias	0.009	0.991	0.000
S42.7 Multiple fractures of clavicle, scapula and humerus	0.009	0.991	0.000
S42.90 Fracture of shoulder girdle, part unspecified (closed)	0.009	0.991	0.000
D68.6 Other Thrombophilia	0.008	0.991	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.009	0.991	0.000
D86.0 Sarcoidosis of lung	0.008	0.991	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.008	0.992	0.000
S42.40 Fracture of lower end of humerus (closed)	0.008	0.992	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.008	0.992	0.000
T21 Burn and corrosion of trunk	0.008	0.992	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.008	0.992	0.000
D75.1 Secondary polycythaemia	0.006	0.992	0.003
S42.91 Fracture of shoulder girdle, part unspecified (open)	0.008	0.992	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.008	0.992	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.008	0.992	0.000
D61 Other aplastic anaemias	0.008	0.992	0.000
S42.41 Fracture of lower end of humerus (open)	0.008	0.992	0.000
S02.20 Fracture of nasal bones (closed)	0.007	0.992	0.000
D68.2 Hereditary deficiency of other clotting factors	0.008	0.992	0.000
S43.1 Dislocation of acromioclavicular joint	0.008	0.992	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.008	0.992	0.000
D51 Vitamin B12 deficiency anaemia	0.008	0.992	0.000
S42.81 Fracture of other parts of shoulder and upper arm (open)	0.007	0.993	0.000
S42.80 Fracture of other parts of shoulder and upper arm (closed)	0.007	0.993	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.007	0.993	0.000
T00-T07 Injuries involving multiple body regions	0.007	0.993	0.000
T21.3 Burn of third degree of trunk	0.007	0.993	0.000
S50-S59 Injuries to the elbow and forearm	0.007	0.993	0.000
S48 Traumatic amputation of shoulder and upper arm	0.007	0.993	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.007	0.993	0.000
S44 Injury of nerves at shoulder and upper arm level	0.007	0.993	0.000
S47 Crushing injury of shoulder and upper arm	0.007	0.993	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.007	0.993	0.000
S40 Superficial injury of shoulder and upper arm	0.007	0.993	0.000
T00 Superficial injuries involving multiple body regions	0.007	0.993	0.000
O46.9 Antepartum haemorrhage, unspecified	0.007	0.993	0.000
T21.1 Burn of first degree of trunk	0.007	0.993	0.000
S42.31 Fracture of shaft of humerus (open)	0.007	0.993	0.000
N95 Menopausal and other perimenopausal disorders	0.007	0.993	0.000
T20 Burn and corrosion of head and neck	0.007	0.993	0.000
D53.9 Nutritional anaemia, unspecified	0.007	0.993	0.000
T25 Burn and corrosion of ankle and foot	0.007	0.993	0.000
S42.01 Fracture of clavicle (open)	0.007	0.993	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.007	0.993	0.000
S90-S99 Injuries to the ankle and foot	0.007	0.993	0.000
D53.8 Other specified nutritional anaemias	0.007	0.993	0.000
D53.2 Scorbutic anaemia	0.007	0.993	0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.007	0.993	0.000
D53.0 Protein deficiency anaemia	0.007	0.993	0.000
D64 Other anaemias	0.007	0.993	0.000
S42.71 Multiple fractures of clavicle, scapula and humerus (open)	0.006	0.993	0.000
T22.0 Burn of unspecified degree of shoulder and upper limb, except wrist and hand	0.007	0.993	0.000
D52 Folate deficiency anaemia	0.006	0.993	0.000
M35.3 Polymyalgia rheumatica	0.000	0.993	0.007
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot	0.007	0.993	0.000
S93.1 Dislocation of toe(s)	0.007	0.993	0.000
Z85.4 Personal history of malignant neoplasm of genital organs	0.006	0.994	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.006	0.994	0.000
T21.2 Burn of second degree of trunk	0.006	0.994	0.000
T00.9 Multiple superficial injuries, unspecified	0.006	0.994	0.000
N95.9 Menopausal and perimenopausal disorder, unspecified	0.006	0.994	0.000
S42.30 Fracture of shaft of humerus (closed)	0.006	0.994	0.000
T08 Fracture of spine, level unspecified	0.006	0.994	0.000
S56 Injury of muscle and tendon at forearm level	0.006	0.994	0.000
T24.2 Burn of second degree of hip and lower limb, except ankle and foot	0.006	0.994	0.000
D64.8 Other specified anaemias	0.006	0.994	0.000
S52.70 Multiple fractures of forearm (closed)	0.006	0.994	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.006	0.994	0.000
T21.7 Corrosion of third degree of trunk	0.006	0.994	0.000
T21.6 Corrosion of second degree of trunk	0.006	0.994	0.000
T21.5 Corrosion of first degree of trunk	0.006	0.994	0.000
T21.4 Corrosion of unspecified degree of trunk	0.006	0.994	0.000
T21.0 Burn of unspecified degree of trunk	0.006	0.994	0.000
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.006	0.994	0.000
S43.6 Sprain and strain of sternoclavicular joint	0.006	0.994	0.000
S43.5 Sprain and strain of acromioclavicular joint	0.006	0.994	0.000
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.006	0.994	0.000
S43.2 Dislocation of sternoclavicular joint	0.006	0.994	0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.006	0.994	0.000
T20.2 Burn of second degree of head and neck	0.006	0.994	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.006	0.994	0.000
S50 Superficial injury of forearm	0.006	0.994	0.000
D60.9 Acquired pure red cell aplasia, unspecified	0.006	0.994	0.000
D60.8 Other acquired pure red cell aplasias	0.006	0.994	0.000
D60.1 Transient acquired pure red cell aplasia	0.006	0.994	0.000
D60.0 Chronic acquired pure red cell aplasia	0.006	0.994	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.006	0.994	0.000
M54.96 Dorsalgia, unspecified (Lumbar region)	0.006	0.994	0.000
T33-T35 Frostbite	0.006	0.994	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.006	0.994	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations