TreeWAS – Variant ID: rs71319465

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
# Top node	1.000	0.000
Chapter XI Diseases of the digestive system	1.000	0.000
M20-M25 Other joint disorders	0.998	0.002
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.996	0.004
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.994	0.006
Chapter V Mental and behavioural disorders	0.994	0.006
M05-M14 Inflammatory polyarthropathies	0.989	0.011
M50-M54 Other dorsopathies	0.983	0.017
K70-K77 Diseases of liver	0.981	0.019
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.979	0.021
M15-M19 Arthrosis	0.978	0.022
M17 Gonarthrosis [arthrosis of knee]	0.974	0.026
M54 Dorsalgia	0.971	0.029
Chapter XIV Diseases of the genitourinary system	0.970	0.030
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.967	0.033
Chapter XX External causes of morbidity and mortality	0.962	0.038
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.961	0.039
M17.9 Gonarthrosis, unspecified	0.961	0.039
N17-N19 Renal failure	0.959	0.041
F10 Mental and behavioural disorders due to use of alcohol	0.953	0.047
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.953	0.047
Chapter XII Diseases of the skin and subcutaneous tissue	0.952	0.048
K90-K93 Other diseases of the digestive system	0.952	0.048
M25 Other joint disorders, not elsewhere classified	0.949	0.051
Chapter I Certain infectious and parasitic diseases	0.949	0.051
K76 Other diseases of liver	0.948	0.052
N17 Acute renal failure	0.948	0.052
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.947	0.053
M54.5 Low back pain	0.945	0.055
M13 Other arthritis	0.944	0.056
N17.9 Acute renal failure, unspecified	0.940	0.060
K50-K52 Noninfective enteritis and colitis	0.934	0.066
D60-D64 Aplastic and other anaemias	0.932	0.068
M70-M79 Other soft tissue disorders	0.932	0.068
R50-R69 General symptoms and signs	0.928	0.072
L00-L08 Infections of the skin and subcutaneous tissue	0.927	0.073
K76.9 Liver disease, unspecified	0.923	0.077
K55-K64 Other diseases of intestines	0.919	0.081
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.914	0.086
M79 Other soft tissue disorders, not elsewhere classified	0.913	0.087
R59 Enlarged lymph nodes	0.910	0.090
M13.9 Arthritis, unspecified	0.905	0.095
D69 Purpura and other haemorrhagic conditions	0.905	0.095
K50 Crohn's disease [regional enteritis]	0.905	0.095
N25-N29 Other disorders of kidney and ureter	0.901	0.099
M21 Other acquired deformities of limbs	0.898	0.102
M54.56 Low back pain (Lumbar region)	0.898	0.102
M45-M49 Spondylopathies	0.897	0.103
L03 Cellulitis	0.896	0.104
K58 Irritable bowel syndrome	0.895	0.105
K92 Other diseases of digestive system	0.894	0.106
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.893	0.107
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.889	0.111
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.886	0.114
N10-N16 Renal tubulo-interstitial diseases	0.885	0.115
R07 Pain in throat and chest	0.880	0.120
R59.0 Localised enlarged lymph nodes	0.877	0.123
K80 Cholelithiasis	0.876	0.124
R07.4 Chest pain, unspecified	0.875	0.125
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.873	0.127
M10 Gout	0.873	0.127
F60-F69 Disorders of adult personality and behaviour	0.873	0.127
M79.6 Pain in limb	0.872	0.128
M17.1 Other primary gonarthrosis	0.872	0.128
K50.9 Crohn's disease, unspecified	0.870	0.130
K58.9 Irritable bowel syndrome without diarrhoea	0.869	0.131
M06 Other rheumatoid arthritis	0.867	0.133
T66-T78 Other and unspecified effects of external causes	0.865	0.135
F17 Mental and behavioural disorders due to use of tobacco	0.865	0.135
M13.96 Arthritis, unspecified (Lower leg)	0.857	0.143
Chapter II Neoplasms	0.854	0.146
M35 Other systemic involvement of connective tissue	0.854	0.146
N28 Other disorders of kidney and ureter, not elsewhere classified	0.851	0.149
F10.1 Harmful use	0.850	0.150
M22 Disorders of patella	0.850	0.150
K56 Paralytic ileus and intestinal obstruction without hernia	0.848	0.152
T36-T50 Poisoning by drugs, medicaments and biological substances	0.844	0.156
K92.2 Gastro-intestinal haemorrhage, unspecified	0.844	0.156
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.844	0.156
M23 Internal derangement of knee	0.843	0.157
Y95 Nosocomial condition	0.836	0.164
R42 Dizziness and giddiness	0.835	0.165
R93 Abnormal findings on diagnostic imaging of other body structures	0.835	0.165
L03.1 Cellulitis of other parts of limb	0.833	0.167
Chapter IV Endocrine, nutritional and metabolic diseases	0.831	0.169
R56 Convulsions, not elsewhere classified	0.830	0.170
M25.8 Other specified joint disorders	0.829	0.171
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.827	0.173
M54.9 Dorsalgia, unspecified	0.826	0.174
M20 Acquired deformities of fingers and toes	0.826	0.174
K86 Other diseases of pancreas	0.825	0.175
M54.57 Low back pain (Lumbosacral region)	0.824	0.176
C15-C26 Malignant neoplasms of digestive organs	0.823	0.177
M25.4 Effusion of joint	0.822	0.178
T81 Complications of procedures, not elsewhere classified	0.821	0.179
K85 Acute pancreatitis	0.821	0.179
F10.0 Acute intoxication	0.819	0.181
D69.3 Idiopathic thrombocytopenic purpura	0.818	0.182
K35-K38 Diseases of appendix	0.816	0.184
K60 Fissure and fistula of anal and rectal regions	0.816	0.184
M25.7 Osteophyte	0.816	0.184
D69.6 Thrombocytopenia, unspecified	0.816	0.184
B95-B98 Bacterial, viral and other infectious agents	0.816	0.184
Chapter X Diseases of the respiratory system	0.815	0.185
A00-A09 Intestinal infectious diseases	0.814	0.186
D64 Other anaemias	0.813	0.187
D70-D77 Other diseases of blood and blood-forming organs	0.812	0.188
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.808	0.192
S20-S29 Injuries to the thorax	0.806	0.194
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.806	0.194
K74 Fibrosis and cirrhosis of liver	0.805	0.195
K65-K67 Diseases of peritoneum	0.804	0.196
R59.1 Generalised enlarged lymph nodes	0.804	0.196
K80.2 Calculus of gallbladder without cholecystitis	0.804	0.196
S70-S79 Injuries to the hip and thigh	0.802	0.198
F17.1 Harmful use	0.798	0.202
S40-S49 Injuries to the shoulder and upper arm	0.793	0.207
R52 Pain, not elsewhere classified	0.793	0.207
E70-E90 Metabolic disorders	0.793	0.207
M79.67 Pain in limb (Ankle and foot)	0.790	0.210
M10.9 Gout, unspecified	0.790	0.210
L03.3 Cellulitis of trunk	0.790	0.210
M65-M68 Disorders of synovium and tendon	0.787	0.213
D50-D53 Nutritional anaemias	0.786	0.214
F60 Specific personality disorders	0.786	0.214
J09-J18 Influenza and pneumonia	0.785	0.215
M17.0 Primary gonarthrosis, bilateral	0.784	0.216
K76.6 Portal hypertension	0.784	0.216
M54.3 Sciatica	0.784	0.216
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.783	0.217
K70 Alcoholic liver disease	0.782	0.217
F10.3 Withdrawal state	0.782	0.218
D37-D48 Neoplasms of uncertain or unknown behaviour	0.782	0.218
M24 Other specific joint derangements	0.781	0.219
M40-M43 Deforming dorsopathies	0.780	0.220
D63 Anaemia in chronic diseases classified elsewhere	0.777	0.223
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.775	0.225
F80-F89 Disorders of psychological development	0.775	0.225
W20-W49 Exposure to inanimate mechanical forces	0.775	0.225
K60.2 Anal fissure, unspecified	0.774	0.226
S90-S99 Injuries to the ankle and foot	0.774	0.226
T78 Adverse effects, not elsewhere classified	0.772	0.228
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.772	0.228
T84.0 Mechanical complication of internal joint prosthesis	0.771	0.229
D62 Acute posthaemorrhagic anaemia	0.771	0.229
F30-F39 Mood [affective] disorders	0.771	0.229
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.770	0.230
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.767	0.233
E87 Other disorders of fluid, electrolyte and acid-base balance	0.767	0.233
M91-M94 Chondropathies	0.764	0.236
M79.8 Other specified soft tissue disorders	0.764	0.236
N13 Obstructive and reflux uropathy	0.763	0.237
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.762	0.238
M54.50 Low back pain (Multiple sites in spine)	0.762	0.238
Chapter VI Diseases of the nervous system	0.761	0.239
J18 Pneumonia, organism unspecified	0.761	0.239
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.761	0.239
D80-D89 Certain disorders involving the immune mechanism	0.760	0.240
R56.8 Other and unspecified convulsions	0.760	0.240
M06.9 Rheumatoid arthritis, unspecified	0.760	0.240
M50 Cervical disk disorders	0.759	0.241
T81.4 Infection following a procedure, not elsewhere classified	0.758	0.242
K50.0 Crohn's disease of small intestine	0.758	0.242
N00-N08 Glomerular diseases	0.755	0.245
Chapter XXII Codes for special purposes	0.755	0.245
M34 Systemic sclerosis	0.755	0.245
N18 Chronic renal failure	0.754	0.246
M21.1 Varus deformity, not elsewhere classified	0.753	0.247
A30-A49 Other bacterial diseases	0.752	0.248
F10.2 Dependence syndrome	0.752	0.248
F10.4 Withdrawal state with delirium	0.750	0.250
F99-F99 Unspecified mental disorder	0.750	0.250
N28.8 Other specified disorders of kidney and ureter	0.749	0.251
F00-F09 Organic, including symptomatic, mental disorders	0.748	0.252
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.748	0.252
T79-T79 Certain early complications of trauma	0.746	0.254
R61 Hyperhidrosis	0.746	0.254
K92.1 Melaena	0.744	0.256
M46 Other inflammatory spondylopathies	0.743	0.257
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.743	0.257
K56.7 Ileus, unspecified	0.742	0.258
E87.1 Hypo-osmolality and hyponatraemia	0.741	0.259
K76.0 Fatty (change of) liver, not elsewhere classified	0.740	0.260
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.740	0.260
M86-M90 Other osteopathies	0.740	0.260
M21.4 Flat foot [pes planus] (acquired)	0.739	0.261
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.738	0.262
L05 Pilonidal cyst	0.738	0.262
T86 Failure and rejection of transplanted organs and tissues	0.738	0.262
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.737	0.263
L80-L99 Other disorders of the skin and subcutaneous tissue	0.735	0.265
M11 Other crystal arthropathies	0.732	0.268
D68 Other coagulation defects	0.731	0.269
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.730	0.270
R50 Fever of unknown origin	0.730	0.270
M13.94 Arthritis, unspecified (Hand)	0.730	0.270
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.728	0.272
M35.3 Polymyalgia rheumatica	0.727	0.273
L02 Cutaneous abscess, furuncle and carbuncle	0.727	0.273
D64.9 Anaemia, unspecified	0.727	0.273
M48 Other spondylopathies	0.727	0.273
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.727	0.273
M79.1 Myalgia	0.726	0.274
M13.0 Polyarthritis, unspecified	0.725	0.274
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.725	0.275
M54.99 Dorsalgia, unspecified (Site unspecified)	0.725	0.275
T88 Other complications of surgical and medical care, not elsewhere classified	0.724	0.275
M54.1 Radiculopathy	0.724	0.276
K58.0 Irritable bowel syndrome with diarrhoea	0.723	0.277
K85.9 Acute pancreatitis, unspecified	0.723	0.277
T81.8 Other complications of procedures, not elsewhere classified	0.723	0.277
B35-B49 Mycoses	0.722	0.278
M05 Seropositive rheumatoid arthritis	0.721	0.279
K56.6 Other and unspecified intestinal obstruction	0.721	0.279
M25.46 Effusion of joint (Lower leg)	0.720	0.280
K56.5 Intestinal adhesions [bands] with obstruction	0.720	0.280
K75 Other inflammatory liver diseases	0.720	0.280
M60-M63 Disorders of muscles	0.717	0.283
M00-M03 Infectious arthropathies	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
L60-L75 Disorders of skin appendages	0.717	0.283
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.716	0.284
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.716	0.284
M33 Dermatopolymyositis	0.716	0.284
M32 Systemic lupus erythematosus	0.716	0.284
M30 Polyarteritis nodosa and related conditions	0.716	0.284
M13.90 Arthritis, unspecified (Multiple sites)	0.716	0.284
T15-T19 Effects of foreign body entering through natural orifice	0.715	0.284
K52 Other non-infective gastro-enteritis and colitis	0.714	0.286
T33-T35 Frostbite	0.714	0.286
T26-T28 Burns and corrosions confined to eye and internal organs	0.714	0.286
T20-T25 Burns and corrosions of external body surface, specified by site	0.714	0.286
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.714	0.286
T00-T07 Injuries involving multiple body regions	0.714	0.286
S10-S19 Injuries to the neck	0.714	0.286
K35 Acute appendicitis	0.714	0.286
M13.98 Arthritis, unspecified (Other)	0.713	0.287
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.713	0.287
D55-D59 Haemolytic anaemias	0.713	0.287
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.713	0.287
F70-F79 Mental retardation	0.713	0.287
L03.2 Cellulitis of face	0.711	0.289
X60-X84 Intentional self-harm	0.710	0.289
C15 Malignant neoplasm of oesophagus	0.710	0.290
M21.0 Valgus deformity, not elsewhere classified	0.709	0.291
W00-W19 Falls	0.709	0.291
M14 Arthropathies in other diseases classified elsewhere	0.709	0.291
M12 Other specific arthropathies	0.709	0.291
M09 Juvenile arthritis in diseases classified elsewhere	0.709	0.291
M08 Juvenile arthritis	0.709	0.291
R07.1 Chest pain on breathing	0.709	0.291
M79.0 Rheumatism, unspecified	0.708	0.292
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.708	0.292
J18.1 Lobar pneumonia, unspecified	0.708	0.292
M20.4 Other hammer toe(s) (acquired)	0.707	0.293
S50-S59 Injuries to the elbow and forearm	0.705	0.294
M22.2 Patellofemoral disorders	0.705	0.295
M10.99 Gout, unspecified (Site unspecified)	0.705	0.295
M53 Other dorsopathies, not elsewhere classified	0.705	0.295
R02 Gangrene, not elsewhere classified	0.704	0.296
M79.62 Pain in limb (Upper arm)	0.703	0.297
K77 Liver disorders in diseases classified elsewhere	0.703	0.297
K73 Chronic hepatitis, not elsewhere classified	0.703	0.297
K72 Hepatic failure, not elsewhere classified	0.703	0.297
K71 Toxic liver disease	0.703	0.297
M47 Spondylosis	0.703	0.297
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.702	0.298
F18 Mental and behavioural disorders due to use of volatile solvents	0.702	0.298
F16 Mental and behavioural disorders due to use of hallucinogens	0.702	0.298
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.702	0.298
F14 Mental and behavioural disorders due to use of cocaine	0.702	0.298
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.702	0.298
F12 Mental and behavioural disorders due to use of cannabinoids	0.702	0.298
F11 Mental and behavioural disorders due to use of opioids	0.702	0.298
C64-C68 Malignant neoplasms of urinary tract	0.702	0.298
M15 Polyarthrosis	0.701	0.299
N19 Unspecified renal failure	0.701	0.299
M17.5 Other secondary gonarthrosis	0.698	0.302
M17.4 Other secondary gonarthrosis, bilateral	0.698	0.302
M17.3 Other posttraumatic gonarthrosis	0.698	0.302
M17.2 Posttraumatic gonarthrosis, bilateral	0.698	0.302
R06 Abnormalities of breathing	0.698	0.302
N18.9 Chronic renal failure, unspecified	0.697	0.303
L90 Atrophic disorders of skin	0.697	0.303
M79.63 Pain in limb (Forearm)	0.696	0.304
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.696	0.304
M54.8 Other dorsalgia	0.696	0.304
M54.6 Pain in thoracic spine	0.696	0.304
M54.0 Panniculitis affecting regions of neck and back	0.696	0.304
M79.66 Pain in limb (Lower leg)	0.695	0.305
F60.9 Personality disorder, unspecified	0.694	0.306
S80-S89 Injuries to the knee and lower leg	0.693	0.306
L50-L54 Urticaria and erythema	0.693	0.307
T87 Complications peculiar to reattachment and amputation	0.693	0.307
T80 Complications following infusion, transfusion and therapeutic injection	0.693	0.307
T83.1 Mechanical complication of other urinary devices and implants	0.693	0.307
M54.4 Lumbago with sciatica	0.692	0.308
N28.0 Ischaemia and infarction of kidney	0.691	0.309
T46 Poisoning by agents primarily affecting the cardiovascular system	0.691	0.309
Y60-Y69 Misadventures to patients during surgical and medical care	0.690	0.310
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.690	0.310
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.690	0.310
Y35-Y36 Legal intervention and operations of war	0.690	0.310
Y10-Y34 Event of undetermined intent	0.690	0.310
Y00-Y09 Assault	0.690	0.310
X85-X99 Assault	0.690	0.310
X58-X59 Accidental exposure to other and unspecified factors	0.690	0.310
X50-X57 Overexertion, travel and privation	0.690	0.310
X40-X49 Accidental poisoning by and exposure to noxious substances	0.690	0.310
X30-X39 Exposure to forces of nature	0.690	0.310
X20-X29 Contact with venomous animals and plants	0.690	0.310
X10-X19 Contact with heat and hot substances	0.690	0.310
X00-X09 Exposure to smoke, fire and flames	0.690	0.310
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.690	0.310
W75-W84 Other accidental threats to breathing	0.690	0.310
W65-W74 Accidental drowning and submersion	0.690	0.310
W50-W64 Exposure to animate mechanical forces	0.690	0.310
V98-V99 Other and unspecified transport accidents	0.690	0.310
V95-V97 Air and space transport accidents	0.690	0.310
V90-V94 Water transport accidents	0.690	0.310
V80-V89 Other land transport accidents	0.690	0.310
V70-V79 Bus occupant injured in transport accident	0.690	0.310
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.690	0.310
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.690	0.310
V40-V49 Car occupant injured in transport accident	0.690	0.310
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.690	0.310
V20-V29 Motorcycle rider injured in transport accident	0.690	0.310
V01-V09 Pedestrian injured in transport accident	0.690	0.310
J18.9 Pneumonia, unspecified	0.689	0.311
R95-R99 Ill-defined and unknown causes of mortality	0.689	0.311
M31 Other necrotising vasculopathies	0.689	0.311
M25.84 Other specified joint disorders (Hand)	0.687	0.313
N40-N51 Diseases of male genital organs	0.687	0.313
C19 Malignant neoplasm of rectosigmoid junction	0.686	0.314
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.684	0.316
K86.3 Pseudocyst of pancreas	0.684	0.316
M80-M85 Disorders of bone density and structure	0.684	0.316
F10.9 Unspecified mental and behavioural disorder	0.684	0.316
F10.8 Other mental and behavioural disorders	0.684	0.316
F10.7 Residual and late-onset psychotic disorder	0.684	0.316
F10.6 Amnesic syndrome	0.684	0.316
F10.5 Psychotic disorder	0.684	0.316
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.683	0.317
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract	0.683	0.317
L10-L14 Bullous disorders	0.683	0.317
K93 Disorders of other digestive organs in diseases classified elsewhere	0.682	0.317
M54.2 Cervicalgia	0.682	0.318
K86.0 Alcohol-induced chronic pancreatitis	0.682	0.318
R94 Abnormal results of function studies	0.682	0.318
K74.6 Other and unspecified cirrhosis of liver	0.682	0.318
C25 Malignant neoplasm of pancreas	0.681	0.319
N28.1 Cyst of kidney, acquired	0.681	0.319
K80.0 Calculus of gallbladder with acute cholecystitis	0.681	0.319
M25.9 Joint disorder, unspecified	0.680	0.319
M25.6 Stiffness of joint, not elsewhere classified	0.680	0.319
M25.3 Other instability of joint	0.680	0.319
M25.2 Flail joint	0.680	0.319
M25.1 Fistula of joint	0.680	0.319
M25.0 Haemarthrosis	0.680	0.319
B99-B99 Other infectious diseases	0.680	0.320
B90-B94 Sequelae of infectious and parasitic diseases	0.680	0.320
B85-B89 Pediculosis, acariasis and other infestations	0.680	0.320
B65-B83 Helminthiases	0.680	0.320
B50-B64 Protozoal diseases	0.680	0.320
B20-B24 Human immunodeficiency virus [HIV] disease	0.680	0.320
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.680	0.320
A80-A89 Viral infections of the central nervous system	0.680	0.320
A75-A79 Rickettsioses	0.680	0.320
A70-A74 Other diseases caused by chlamydiae	0.680	0.320
A65-A69 Other spirochaetal diseases	0.680	0.320
A50-A64 Infections with a predominantly sexual mode of transmission	0.680	0.320
A20-A28 Certain zoonotic bacterial diseases	0.680	0.320
A15-A19 Tuberculosis	0.680	0.320
K76.7 Hepatorenal syndrome	0.680	0.320
K76.5 Hepatic veno-occlusive disease	0.680	0.320
K76.4 Peliosis hepatis	0.680	0.320
K76.3 Infarction of liver	0.680	0.320
K76.2 Central haemorrhagic necrosis of liver	0.680	0.320
K76.1 Chronic passive congestion of liver	0.680	0.320
N17.8 Other acute renal failure	0.680	0.320
N17.2 Acute renal failure with medullary necrosis	0.680	0.320
N17.1 Acute renal failure with acute cortical necrosis	0.680	0.320
N17.0 Acute renal failure with tubular necrosis	0.680	0.320
M25.76 Osteophyte (Lower leg)	0.680	0.320
M79.5 Residual foreign body in soft tissue	0.679	0.320
R47-R49 Symptoms and signs involving speech and voice	0.679	0.321
D67 Hereditary factor IX deficiency	0.679	0.321
D66 Hereditary factor VIII deficiency	0.679	0.321
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.679	0.321
K80.1 Calculus of gallbladder with other cholecystitis	0.679	0.321
M54.55 Low back pain (Thoracolumbar region)	0.678	0.322
M54.54 Low back pain-Thoracic	0.678	0.322
M54.53 Low back pain-Cervicothoracic	0.678	0.322
M54.52 Low back pain-Cervical	0.678	0.322
M54.51 Low back pain-Occipit-atl-axl	0.678	0.322
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.677	0.323
M13.8 Other specified arthritis	0.677	0.323
M13.1 Monoarthritis, not elsewhere classified	0.677	0.323
L03.9 Cellulitis, unspecified	0.676	0.324
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.675	0.325
M77 Other enthesopathies	0.674	0.326
T84.2 Mechanical complication of internal fixation device of other bones	0.673	0.327
M07 Psoriatic and enteropathic arthropathies	0.673	0.327
N28.9 Disorder of kidney and ureter, unspecified	0.673	0.327
M22.4 Chondromalacia patellae	0.672	0.328
R90 Abnormal findings on diagnostic imaging of central nervous system	0.671	0.329
M20.5 Other deformities of toe(s) (acquired)	0.670	0.330
L90.5 Scar conditions and fibrosis of skin	0.669	0.331
M06.0 Seronegative rheumatoid arthritis	0.669	0.331
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.668	0.332
M25.74 Osteophyte (Hand)	0.668	0.332
M76 Enthesopathies of lower limb, excluding foot	0.668	0.332
M73 Soft tissue disorders in diseases classified elsewhere	0.668	0.332
M71 Other bursopathies	0.668	0.332
B97 Viral agents as the cause of diseases classified to other chapters	0.667	0.333
D63.0 Anaemia in neoplastic disease	0.667	0.333
M54.59 Low back pain (Site unspecified)	0.667	0.333
M18 Arthrosis of first carpometacarpal joint	0.666	0.334
M23.2 Derangement of meniscus due to old tear or injury	0.666	0.334
R59.9 Enlarged lymph nodes, unspecified	0.666	0.334
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.665	0.335
R62 Lack of expected normal physiological development	0.665	0.335
R57 Shock, not elsewhere classified	0.665	0.335
R64 Cachexia	0.665	0.335
R58 Haemorrhage, not elsewhere classified	0.665	0.335
M70 Soft tissue disorders related to use, overuse and pressure	0.665	0.335
V10-V19 Pedal cyclist injured in transport accident	0.665	0.335
L04 Acute lymphadenitis	0.665	0.335
L01 Impetigo	0.665	0.335
L00 Staphylococcal scalded skin syndrome	0.665	0.335
R52.1 Chronic intractable pain	0.665	0.335
B15-B19 Viral hepatitis	0.664	0.336
R07.2 Precordial pain	0.663	0.337
S72 Fracture of femur	0.663	0.337
T78.2 Anaphylactic shock, unspecified	0.662	0.338
M54.39 Sciatica (Site unspecified)	0.662	0.338
K70.9 Alcoholic liver disease, unspecified	0.662	0.338
D72 Other disorders of white blood cells	0.661	0.339
K55 Vascular disorders of intestine	0.661	0.339
M45 Ankylosing spondylitis	0.661	0.339
M79.60 Pain in limb (Multiple sites)	0.661	0.339
C26 Malignant neoplasm of other and ill-defined digestive organs	0.660	0.339
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.660	0.339
L08 Other local infections of skin and subcutaneous tissue	0.660	0.340
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.659	0.341
D61 Other aplastic anaemias	0.659	0.341
K64 Haemorrhoids and perianal venous thrombosis	0.659	0.341
C20 Malignant neoplasm of rectum	0.659	0.341
Y86 Sequelae of other accidents	0.659	0.341
R68 Other general symptoms and signs	0.658	0.342
M65 Synovitis and tenosynovitis	0.657	0.343
R60 Oedema, not elsewhere classified	0.657	0.343
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.655	0.345
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.655	0.345
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.655	0.345
T84.3 Mechanical complication of other bone devices, implants and grafts	0.655	0.345
M79.9 Soft tissue disorder, unspecified	0.655	0.345
M79.4 Hypertrophy of (infrapatellar) fat pad	0.655	0.345
M79.3 Panniculitis, unspecified	0.655	0.345
M79.2 Neuralgia and neuritis, unspecified	0.655	0.345
M35.0 Sicca syndrome [Sjogren]	0.655	0.345
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.655	0.345
T83.0 Mechanical complication of urinary (indwelling) catheter	0.654	0.346
M23.8 Other internal derangements of knee	0.654	0.346
T83.3 Mechanical complication of intra-uterine contraceptive device	0.654	0.346
K80.4 Calculus of bile duct with cholecystitis	0.653	0.347
K90 Intestinal malabsorption	0.653	0.347
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.653	0.347
M25.87 Other specified joint disorders (Ankle and foot)	0.652	0.348
S22 Fracture of rib(s), sternum and thoracic spine	0.651	0.348
M23.3 Other meniscus derangements	0.651	0.349
B07 Viral warts	0.650	0.350
A04 Other bacterial intestinal infections	0.650	0.350
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.650	0.350
M13.93 Arthritis, unspecified (Forearm)	0.649	0.351
M13.92 Arthritis, unspecified (Upper arm)	0.649	0.351
M13.91 Arthritis, unspecified (Shoulder region)	0.649	0.351
D69.9 Haemorrhagic condition, unspecified	0.649	0.351
D69.8 Other specified haemorrhagic conditions	0.649	0.351
D69.5 Secondary thrombocytopenia	0.649	0.351
D69.4 Other primary thrombocytopenia	0.649	0.351
D69.2 Other nonthrombocytopenic purpura	0.649	0.351
D69.1 Qualitative platelet defects	0.649	0.351
D69.0 Allergic purpura	0.649	0.351
K50.8 Other Crohn's disease	0.648	0.351
R06.0 Dyspnoea	0.648	0.352
M72 Fibroblastic disorders	0.648	0.352
K86.1 Other chronic pancreatitis	0.647	0.353
N29 Other disorders of kidney and ureter in diseases classified elsewhere	0.646	0.354
N27 Small kidney of unknown cause	0.646	0.354
N25 Disorders resulting from impaired renal tubular function	0.646	0.354
N26 Unspecified contracted kidney	0.646	0.354
M20.6 Acquired deformity of toe(s), unspecified	0.646	0.354
J40-J47 Chronic lower respiratory diseases	0.646	0.354
C51-C58 Malignant neoplasms of female genital organs	0.646	0.354
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.645	0.355
R52.2 Other chronic pain	0.645	0.355
M21.9 Acquired deformity of limb, unspecified	0.644	0.356
M21.8 Other specified acquired deformities of limbs	0.644	0.356

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations