TreeWAS – Variant ID: rs713875

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
E03 Other hypothyroidism	0.768	0.232	0.000
E03.8 Other specified hypothyroidism	0.634	0.366	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.618	0.382	0.000
E03.1 Congenital hypothyroidism without goitre	0.611	0.389	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.572	0.428	0.000
E03.5 Myxoedema coma	0.550	0.450	0.000
E03.4 Atrophy of thyroid (acquired)	0.550	0.450	0.000
E03.3 Postinfectious hypothyroidism	0.550	0.450	0.000
E00-E07 Disorders of thyroid gland	0.163	0.837	0.000
E06 Thyroiditis	0.142	0.857	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.125	0.875	0.000
E07 Other disorders of thyroid	0.124	0.876	0.000
E06.3 Autoimmune thyroiditis	0.122	0.878	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.117	0.883	0.000
E00 Congenital iodine-deficiency syndrome	0.117	0.883	0.000
E06.9 Thyroiditis, unspecified	0.110	0.890	0.000
E06.5 Other chronic thyroiditis	0.107	0.893	0.000
S22.40 Multiple fractures of ribs (closed)	0.106	0.894	0.000
E07.9 Disorder of thyroid, unspecified	0.106	0.894	0.000
E06.4 Drug-induced thyroiditis	0.102	0.898	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.102	0.898	0.000
E06.1 Subacute thyroiditis	0.102	0.898	0.000
E06.0 Acute thyroiditis	0.102	0.898	0.000
E07.1 Dyshormogenetic goitre	0.089	0.911	0.000
E07.0 Hypersecretion of calcitonin	0.089	0.911	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.084	0.916	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.084	0.916	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.084	0.916	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.084	0.916	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.084	0.916	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.084	0.916	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.084	0.916	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.084	0.916	0.000
E07.8 Other specified disorders of thyroid	0.070	0.930	0.000
S22.4 Multiple fractures of ribs	0.055	0.945	0.000
H83.0 Labyrinthitis	0.054	0.946	0.000
S82.40 Fracture of fibula alone (closed)	0.046	0.954	0.000
S82.4 Fracture of fibula alone	0.043	0.957	0.000
S82 Fracture of lower leg, including ankle	0.041	0.959	0.000
S22.41 Multiple fractures of ribs (open)	0.040	0.960	0.000
D50.8 Other iron deficiency anaemias	0.039	0.961	0.000
S80.9 Superficial injury of lower leg, unspecified	0.039	0.961	0.000
S82.2 Fracture of shaft of tibia	0.038	0.962	0.000
S82.6 Fracture of lateral malleolus	0.037	0.963	0.000
S82.7 Multiple fractures of lower leg	0.037	0.963	0.000
S82.20 Fracture of shaft of tibia (closed)	0.036	0.964	0.000
E04 Other non-toxic goitre	0.035	0.965	0.000
S82.70 Multiple fractures of lower leg (closed)	0.034	0.966	0.000
S82.0 Fracture of patella	0.034	0.966	0.000
S80-S89 Injuries to the knee and lower leg	0.034	0.966	0.000
S82.60 Fracture of lateral malleolus (closed)	0.034	0.966	0.000
S80 Superficial injury of lower leg	0.033	0.967	0.000
S81 Open wound of lower leg	0.033	0.967	0.000
S82.9 Fracture of lower leg, part unspecified	0.032	0.968	0.000
S81.8 Open wound of other parts of lower leg	0.031	0.969	0.000
S82.41 Fracture of fibula alone (open)	0.031	0.969	0.000
S82.01 Fracture of patella (open)	0.030	0.970	0.000
S82.61 Fracture of lateral malleolus (open)	0.029	0.971	0.000
S81.7 Multiple open wounds of lower leg	0.029	0.971	0.000
S82.21 Fracture of shaft of tibia (open)	0.029	0.971	0.000
S81.9 Open wound of lower leg, part unspecified	0.028	0.972	0.000
S82.71 Multiple fractures of lower leg (open)	0.027	0.973	0.000
S82.90 Fracture of lower leg, part unspecified (closed)	0.025	0.975	0.000
S82.5 Fracture of medial malleolus	0.025	0.975	0.000
Z45.2 Adjustment and management of vascular access device	0.025	0.975	0.000
E04.8 Other specified non-toxic goitre	0.025	0.975	0.000
S87 Crushing injury of lower leg	0.025	0.975	0.000
S80.0 Contusion of knee	0.025	0.975	0.000
S88 Traumatic amputation of lower leg	0.024	0.975	0.000
S85 Injury of blood vessels at lower leg level	0.024	0.975	0.000
S84 Injury of nerves at lower leg level	0.024	0.975	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.024	0.976	0.000
S82.91 Fracture of lower leg, part unspecified (open)	0.023	0.977	0.000
S82.00 Fracture of patella (closed)	0.023	0.977	0.000
E04.9 Non-toxic goitre, unspecified	0.022	0.978	0.000
S86 Injury of muscle and tendon at lower leg level	0.022	0.978	0.000
H83 Other diseases of inner ear	0.021	0.979	0.000
E04.0 Non-toxic diffuse goitre	0.021	0.979	0.000
S80.7 Multiple superficial injuries of lower leg	0.021	0.979	0.000
S89 Other and unspecified injuries of lower leg	0.020	0.980	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.019	0.981	0.000
S82.1 Fracture of upper end of tibia	0.019	0.981	0.000
N18.5 Chronic kidney disease, stage 5	0.019	0.981	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.019	0.981	0.000
S87.8 Crushing injury of other and unspecified parts of lower leg	0.019	0.981	0.000
S80.8 Other superficial injuries of lower leg	0.018	0.982	0.000
S87.0 Crushing injury of knee	0.018	0.982	0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.000	0.982	0.018
E05.5 Thyroid crisis or storm	0.018	0.982	0.000
E05.4 Thyrotoxicosis factitia	0.018	0.982	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.018	0.982	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.018	0.982	0.000
S84.9 Injury of unspecified nerve at lower leg level	0.018	0.982	0.000
S84.8 Injury of other nerves at lower leg level	0.018	0.982	0.000
S84.7 Injury of multiple nerves at lower leg level	0.018	0.982	0.000
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.018	0.982	0.000
S84.1 Injury of peroneal nerve at lower leg level	0.018	0.982	0.000
S84.0 Injury of tibial nerve at lower leg level	0.018	0.982	0.000
S85.9 Injury of unspecified blood vessel at lower leg level	0.018	0.982	0.000
S85.8 Injury of other blood vessels at lower leg level	0.018	0.982	0.000
S85.7 Injury of multiple blood vessels at lower leg level	0.018	0.982	0.000
S85.5 Injury of popliteal vein	0.018	0.982	0.000
S85.4 Injury of lesser saphenous vein at lower leg level	0.018	0.982	0.000
S85.3 Injury of greater saphenous vein at lower leg level	0.018	0.982	0.000
S85.2 Injury of peroneal artery	0.018	0.982	0.000
S85.1 Injury of (anterior)(posterior) tibial artery	0.018	0.982	0.000
S85.0 Injury of popliteal artery	0.018	0.982	0.000
S88.9 Traumatic amputation of lower leg, level unspecified	0.018	0.982	0.000
S88.1 Traumatic amputation at level between knee and ankle	0.018	0.982	0.000
S88.0 Traumatic amputation at knee level	0.018	0.982	0.000
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.017	0.983	0.000
S82.51 Fracture of medial malleolus (open)	0.017	0.983	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.017	0.983	0.000
S82.8 Fractures of other parts of lower leg	0.017	0.983	0.000
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.017	0.983	0.000
S86.0 Injury of Achilles tendon	0.016	0.984	0.000
S86.7 Injury of multiple muscles and tendons at lower leg level	0.016	0.984	0.000
S82.50 Fracture of medial malleolus (closed)	0.016	0.984	0.000
H83.2 Labyrinthine dysfunction	0.016	0.984	0.000
S86.8 Injury of other muscles and tendons at lower leg level	0.015	0.985	0.000
S82.3 Fracture of lower end of tibia	0.015	0.985	0.000
H83.1 Labyrinthine fistula	0.015	0.985	0.000
H83.9 Disease of inner ear, unspecified	0.015	0.985	0.000
H83.8 Other specified diseases of inner ear	0.015	0.985	0.000
E04.2 Non-toxic multinodular goitre	0.015	0.985	0.000
S89.8 Other specified injuries of lower leg	0.015	0.985	0.000
S89.7 Multiple injuries of lower leg	0.014	0.986	0.000
S89.1 Other specified injuries of lower leg	0.014	0.986	0.000
S89.0 Multiple injuries of lower leg	0.014	0.986	0.000
S22.9 Fracture of bony thorax, part unspecified	0.014	0.986	0.000
S22.8 Fracture of other parts of bony thorax	0.014	0.986	0.000
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.013	0.986	0.000
S22.5 Flail chest	0.013	0.987	0.000
E05.8 Other thyrotoxicosis	0.013	0.987	0.000
H83.3 Noise effects on inner ear	0.013	0.987	0.000
S22.3 Fracture of rib	0.013	0.987	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.000	0.987	0.013
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.012	0.988	0.000
S82.86 Maisonneuve's fracture	0.012	0.988	0.000
S22.1 Multiple fractures of thoracic spine	0.012	0.988	0.000
S22.0 Fracture of thoracic vertebra	0.012	0.988	0.000
S22.2 Fracture of sternum	0.012	0.988	0.000
S86.00 Unspecified injury of Achilles tendon	0.011	0.988	0.000
S82.11 Fracture of upper end of tibia (open)	0.011	0.989	0.000
E04.1 Non-toxic single thyroid nodule	0.011	0.989	0.000
Y40.0 Penicillins	0.011	0.989	0.000
Z49.1 Extracorporeal dialysis	0.010	0.990	0.000
I80 Phlebitis and thrombophlebitis	0.000	0.990	0.010
S81.0 Open wound of knee	0.010	0.990	0.000
M41.96 Scoliosis, unspecified (Lumbar region)	0.010	0.990	0.000
S82.81 Fractures of other parts of lower leg (open)	0.010	0.990	0.000
S22.81 Fracture of other parts of bony thorax (open)	0.010	0.990	0.000
S22.80 Fracture of other parts of bony thorax (closed)	0.010	0.990	0.000
S22.91 Fracture of bony thorax, part unspecified (open)	0.010	0.990	0.000
S22.90 Fracture of bony thorax, part unspecified (closed)	0.010	0.990	0.000
S22.51 Flail chest (open)	0.010	0.990	0.000
S22.31 Fracture of rib (open)	0.009	0.991	0.000
E10.3 With ophthalmic complications	0.009	0.991	0.000
S22.50 Flail chest (closed)	0.009	0.991	0.000
S22.11 Multiple fractures of thoracic spine (open)	0.009	0.991	0.000
N18.0 End-stage renal disease	0.009	0.991	0.000
S20-S29 Injuries to the thorax	0.009	0.991	0.000
S22.01 Fracture of thoracic vertebra (open)	0.009	0.991	0.000
S89.9 Unspecified injury of lower leg	0.009	0.991	0.000
S22.21 Fracture of sternum (open)	0.009	0.991	0.000
S14 Injury of nerves and spinal cord at neck level	0.009	0.991	0.000
S82.10 Fracture of upper end of tibia (closed)	0.008	0.991	0.000
S22.30 Fracture of rib (closed)	0.008	0.992	0.000
E10 Insulin-dependent diabetes mellitus	0.008	0.992	0.000
E10.1 With ketoacidosis	0.008	0.992	0.000
E10.2 With renal complications	0.008	0.992	0.000
S14.3 Injury of brachial plexus	0.008	0.992	0.000
S10-S19 Injuries to the neck	0.008	0.992	0.000
N18 Chronic renal failure	0.008	0.992	0.000
S14.1 Other and unspecified injuries of cervical spinal cord	0.008	0.992	0.000
E10.4 With neurological complications	0.008	0.992	0.000
T14.0 Superficial injury of unspecified body region	0.008	0.992	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.007	0.992	0.000
S82.31 Fracture of lower end of tibia (open)	0.007	0.993	0.000
N18.8 Other chronic renal failure	0.007	0.993	0.000
S19 Other and unspecified injuries of neck	0.007	0.993	0.000
S24 Injury of nerves and spinal cord at thorax level	0.007	0.993	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.007	0.993	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.007	0.993	0.000
T14 Injury of unspecified body region	0.007	0.993	0.000
S12 Fracture of neck	0.007	0.993	0.000
S27 Injury of other and unspecified intrathoracic organs	0.007	0.993	0.000
S12.20 Fracture of other specified cervical vertebra (closed)	0.007	0.993	0.000
S12.2 Fracture of other specified cervical vertebra	0.007	0.993	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.007	0.993	0.000
S22.20 Fracture of sternum (closed)	0.007	0.993	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.007	0.993	0.000
S26 Injury of heart	0.007	0.993	0.000
S25 Injury of blood vessels of thorax	0.007	0.993	0.000
Z99.2 Dependence on renal dialysis	0.007	0.993	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.007	0.993	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.007	0.993	0.000
I80.8 Phlebitis and thrombophlebitis of other sites	0.000	0.993	0.007
S19.8 Other specified injuries of neck	0.007	0.993	0.000
T23 Burn and corrosion of wrist and hand	0.007	0.993	0.000
S20 Superficial injury of thorax	0.007	0.993	0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.000	0.993	0.007
Z99.8 Dependence on other enabling machines and devices	0.007	0.993	0.000
N02.8 Other	0.006	0.993	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.006	0.994	0.000
S14.6 Injury of other and unspecified nerves of neck	0.006	0.994	0.000
S14.5 Injury of cervical sympathetic nerves	0.006	0.994	0.000
S14.4 Injury of peripheral nerves of neck	0.006	0.994	0.000
S14.2 Injury of nerve root of cervical spine	0.006	0.994	0.000
S14.0 Concussion and oedema of cervical spinal cord	0.006	0.994	0.000
T25 Burn and corrosion of ankle and foot	0.006	0.994	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.006	0.994	0.000
E10.7 With multiple complications	0.006	0.994	0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.006	0.994	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.006	0.994	0.000
T08 Fracture of spine, level unspecified	0.006	0.994	0.000
T23.0 Burn of unspecified degree of wrist and hand	0.006	0.994	0.000
T25.3 Burn of third degree of ankle and foot	0.006	0.994	0.000
S10 Superficial injury of neck	0.006	0.994	0.000
S19.9 Unspecified injury of neck	0.006	0.994	0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.006	0.994	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.006	0.994	0.000
T23.2 Burn of second degree of wrist and hand	0.006	0.994	0.000
S17 Crushing injury of neck	0.006	0.994	0.000
S15 Injury of blood vessels at neck level	0.006	0.994	0.000
S18 Traumatic amputation at neck level	0.006	0.994	0.000
S16 Injury of muscle and tendon at neck level	0.006	0.994	0.000
Z99.3 Dependence on wheelchair	0.006	0.994	0.000
E10.8 With unspecified complications	0.006	0.994	0.000
N18.4 Chronic kidney disease, stage 4	0.006	0.994	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.006	0.994	0.000
S24.1 Other and unspecified injuries of thoracic spinal cord	0.006	0.994	0.000
S27.0 Traumatic pneumothorax	0.006	0.994	0.000
E10.6 With other specified complications	0.006	0.994	0.000
T98 Sequelae of other and unspecified effects of external causes	0.006	0.994	0.000
S36 Injury of intra-abdominal organs	0.006	0.994	0.000
S19.7 Multiple injuries of neck	0.005	0.994	0.000
D50 Iron deficiency anaemia	0.006	0.994	0.000
S30.0 Contusion of lower back and pelvis	0.006	0.994	0.000
S11 Open wound of neck	0.005	0.994	0.000
E10.9 Without complications	0.006	0.994	0.000
S12.7 Multiple fractures of cervical spine	0.005	0.994	0.000
T14.6 Injury of tendons and muscles of unspecified body region	0.005	0.995	0.000
T09 Other injuries of spine and trunk, level unspecified	0.005	0.995	0.000
T79-T79 Certain early complications of trauma	0.005	0.995	0.000
S12.9 Fracture of neck, part unspecified	0.005	0.995	0.000
T13 Other injuries of lower limb, level unspecified	0.005	0.995	0.000
S30.2 Contusion of external genital organs	0.005	0.995	0.000
T14.4 Injury of nerve(s) of unspecified body region	0.005	0.995	0.000
T79.7 Traumatic subcutaneous emphysema	0.005	0.995	0.000
T11 Other injuries of upper limb, level unspecified	0.005	0.995	0.000
N18.1 Chronic kidney disease, stage 1	0.005	0.995	0.000
S24.6 Injury of unspecified nerve of thorax	0.005	0.995	0.000
S24.5 Injury of other nerves of thorax	0.005	0.995	0.000
S24.4 Injury of thoracic sympathetic nerves	0.005	0.995	0.000
S24.3 Injury of peripheral nerves of thorax	0.005	0.995	0.000
S24.2 Injury of nerve root of thoracic spine	0.005	0.995	0.000
S24.0 Concussion and oedema of thoracic spinal cord	0.005	0.995	0.000
S20.2 Contusion of thorax	0.005	0.995	0.000
S20.1 Other and unspecified superficial injuries of breast	0.005	0.995	0.000
S82.30 Fracture of lower end of tibia (closed)	0.005	0.995	0.000
T12.X1 Fracture of lower limb, level unspecified (open)	0.005	0.995	0.000
T12.X0 Fracture of lower limb, level unspecified (closed)	0.005	0.995	0.000
T12 Fracture of lower limb, level unspecified	0.005	0.995	0.000
T10.X1 Fracture of upper limb, level unspecified (open)	0.005	0.995	0.000
T10.X0 Fracture of upper limb, level unspecified (closed)	0.005	0.995	0.000
T10 Fracture of upper limb, level unspecified	0.005	0.995	0.000
T08.X1 Fracture of spine, level unspecified (open)	0.005	0.995	0.000
T08.X0 Fracture of spine, level unspecified (closed)	0.005	0.995	0.000
S12.8 Fracture of other parts of neck	0.005	0.995	0.000
T14.2 Fracture of unspecified body region	0.005	0.995	0.000
T14.8 Other injuries of unspecified body region	0.005	0.995	0.000
T14.7 Crushing injury and traumatic amputation of unspecified body region	0.005	0.995	0.000
T14.5 Injury of blood vessel(s) of unspecified body region	0.005	0.995	0.000
T14.3 Dislocation, sprain and strain of unspecified body region	0.005	0.995	0.000
T25.0 Burn of unspecified degree of ankle and foot	0.005	0.995	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.005	0.995	0.000
T93 Sequelae of injuries of lower limb	0.005	0.995	0.000
T91.3 Sequelae of injury of spinal cord	0.005	0.995	0.000
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.005	0.995	0.000
S27.2 Traumatic heamopneumothorax	0.005	0.995	0.000
S37 Injury of urinary and pelvic organs	0.005	0.995	0.000
S27.9 Injury of unspecified intrathoracic organ	0.005	0.995	0.000
S27.7 Multiple injuries of intrathoracic organs	0.005	0.995	0.000
S27.6 Injury of pleura	0.005	0.995	0.000
S27.5 Injury of thoracic trachea	0.005	0.995	0.000
S27.4 Injury of bronchus	0.005	0.995	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.005	0.995	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.005	0.995	0.000
S12.21 Fracture of other specified cervical vertebra (open)	0.005	0.995	0.000
S23.5 Sprain and strain of other and unspecified parts of thorax	0.005	0.995	0.000
S23.4 Sprain and strain of ribs and sternum	0.005	0.995	0.000
S23.3 Sprain and strain of thoracic spine	0.005	0.995	0.000
S23.2 Dislocation of other and unspecified parts of thorax	0.005	0.995	0.000
S23.1 Dislocation of thoracic vertebra	0.005	0.995	0.000
S23.0 Traumatic rupture of thoracic intervertebral disk	0.005	0.995	0.000
S25.9 Injury of unspecified blood vessel of thorax	0.005	0.995	0.000
S25.8 Injury of other blood vessels of thorax	0.005	0.995	0.000
S25.7 Injury of multiple blood vessels of thorax	0.005	0.995	0.000
S25.5 Injury of intercostal blood vessels	0.005	0.995	0.000
S25.4 Injury of pulmonary blood vessels	0.005	0.995	0.000
S25.3 Injury of innominate or subclavian vein	0.005	0.995	0.000
S25.2 Injury of superior vena cava	0.005	0.995	0.000
S25.1 Injury of innominate or subclavian artery	0.005	0.995	0.000
S25.0 Injury of thoracic aorta	0.005	0.995	0.000
S26.9 Injury of heart, unspecified	0.005	0.995	0.000
S26.8 Other injuries of heart	0.005	0.995	0.000
S26.0 Injury of heart with haemopericardium	0.005	0.995	0.000
S28.1 Traumatic amputation of part of thorax	0.005	0.995	0.000
S28.0 Crushed chest	0.005	0.995	0.000
S20.7 Multiple superficial injuries of thorax	0.005	0.995	0.000
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.005	0.995	0.000
S27.8 Injury of other specified intrathoracic organs	0.005	0.995	0.000
S27.1 Traumatic haemothorax	0.005	0.995	0.000
S36.1 Injury of liver or gallbladder	0.005	0.995	0.000
T23.3 Burn of third degree of wrist and hand	0.005	0.995	0.000
N18.2 Chronic kidney disease, stage 2	0.005	0.995	0.000
T00-T07 Injuries involving multiple body regions	0.005	0.995	0.000
T23.7 Corrosion of third degree of wrist and hand	0.005	0.995	0.000
T23.6 Corrosion of second degree of wrist and hand	0.005	0.995	0.000
T23.5 Corrosion of first degree of wrist and hand	0.005	0.995	0.000
T23.4 Corrosion of unspecified degree of wrist and hand	0.005	0.995	0.000
T21 Burn and corrosion of trunk	0.005	0.995	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.005	0.995	0.000
T95 Sequelae of burns, corrosions and frostbite	0.005	0.995	0.000
S10.9 Superficial injury of neck, part unspecified	0.005	0.995	0.000
S27.3 Other injuries of lung	0.005	0.995	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.005	0.995	0.000
E10.5 With peripheral circulatory complications	0.005	0.995	0.000
T92 Sequelae of injuries of upper limb	0.005	0.995	0.000
S82.80 Fractures of other parts of lower leg (closed)	0.005	0.995	0.000
S12.0 Fracture of first cervical vertebra	0.005	0.995	0.000
T14.9 Injury, unspecified	0.005	0.995	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.005	0.995	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.005	0.995	0.000
T33-T35 Frostbite	0.005	0.995	0.000
T25.7 Corrosion of third degree of ankle and foot	0.005	0.995	0.000
T25.6 Corrosion of second degree of ankle and foot	0.005	0.995	0.000
T25.5 Corrosion of first degree of ankle and foot	0.005	0.995	0.000
T25.4 Corrosion of unspecified degree of ankle and foot	0.005	0.995	0.000
T25.1 Burn of first degree of ankle and foot	0.005	0.995	0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.000	0.995	0.005
T91 Sequelae of injuries of neck and trunk	0.005	0.995	0.000
S10.8 Superficial injury of other parts of neck	0.005	0.995	0.000
S29 Other and unspecified injuries of thorax	0.005	0.995	0.000
T01 Open wounds involving multiple body regions	0.005	0.995	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.005	0.995	0.000
S36.10 Injury of liver or gallbladder (without open wound into cavity)	0.005	0.995	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.005	0.995	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.005	0.995	0.000
S37.0 Injury of kidney	0.005	0.995	0.000
T14.1 Open wound of unspecified body region	0.005	0.995	0.000
S21 Open wound of thorax	0.004	0.995	0.000
S20.0 Contusion of breast	0.005	0.995	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.005	0.995	0.000
I12.9 Hypertensive renal disease without renal failure	0.005	0.995	0.000
S10.7 Multiple superficial injuries of neck	0.005	0.995	0.000
S10.0 Contusion of throat	0.005	0.995	0.000
T13.0 Superficial injury of lower limb, level unspecified	0.005	0.995	0.000
T20 Burn and corrosion of head and neck	0.005	0.995	0.000
R52.1 Chronic intractable pain	0.005	0.995	0.000
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.005	0.995	0.000
Z99.4 Dependence on artificial heart	0.005	0.995	0.000
Z99.0 Dependence on aspirator	0.005	0.995	0.000
S36.8 Injury of other intra-abdominal organs	0.005	0.995	0.000
S12.1 Fracture of second cervical vertebra	0.004	0.995	0.000
S20.8 Superficial injuries of other and unspecified parts of thorax	0.005	0.995	0.000
S39.8 Other specified injuries of abdomen, lower back and pelvis	0.005	0.995	0.000
T09.2 Dislocation, strain and sprain of unspecified joint and ligament of trunk	0.005	0.995	0.000
T23.1 Burn of first degree of wrist and hand	0.004	0.995	0.000
S15.9 Injury of unspecified blood vessel at neck level	0.004	0.995	0.000
S15.8 Injury of other blood vessels at neck level	0.004	0.995	0.000
S15.7 Injury of multiple blood vessels at neck level	0.004	0.995	0.000
S15.3 Injury of internal jugular vein	0.004	0.995	0.000
S15.2 Injury of external jugular vein	0.004	0.995	0.000
S15.1 Injury of vertebral artery	0.004	0.995	0.000
S15.0 Injury of carotid artery	0.004	0.995	0.000
S17.9 Crushing injury of neck, part unspecified	0.004	0.995	0.000
S17.8 Crushing injury of other parts of neck	0.004	0.995	0.000
S17.0 Crushing injury of larynx and traches	0.004	0.995	0.000
S20.4 Other superficial injuries of back wall of thorax	0.004	0.995	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.004	0.995	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.004	0.995	0.000
Z99.9 Dependence on unspecified enabling machine and device	0.004	0.995	0.000
S11.8 Open wound of other parts of neck	0.004	0.995	0.000
T25.2 Burn of second degree of ankle and foot	0.004	0.995	0.000
T11.1 Open wound of upper limb, level unspecified	0.004	0.996	0.000
S37.00 Injury of kidney (without open wound into cavity)	0.004	0.996	0.000
T22.0 Burn of unspecified degree of shoulder and upper limb, except wrist and hand	0.004	0.996	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.004	0.996	0.000
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.004	0.996	0.000
T09.0 Superficial injury of trunk, level unspecified	0.004	0.996	0.000
T98.1 Sequelae of other and unspecified effects of external causes	0.004	0.996	0.000
E10.0 With coma	0.004	0.996	0.000
J35.1 Hypertrophy of tonsils	0.004	0.996	0.000
M41.9 Scoliosis, unspecified	0.004	0.996	0.000
S12.70 Multiple fractures of cervical spine (closed)	0.004	0.996	0.000
T26 Burn and corrosion confined to eye and adnexa	0.004	0.996	0.000
S12.90 Fracture of neck, part unspecified (closed)	0.004	0.996	0.000
T98.2 Sequelae of certain early complications of trauma	0.004	0.996	0.000
T98.0 Sequelae of effects of foreign body entering through natural orifice	0.004	0.996	0.000
D50.1 Sideropenic dysphagia	0.004	0.996	0.000
S10.1 Other and unspecified superficial injuries of throat	0.004	0.996	0.000
S20.3 Other superficial injuries of front wall of thorax	0.004	0.996	0.000
S36.9 Injury of unspecified intra-abdominal organ	0.004	0.996	0.000
S36.7 Injury of multiple intra-abdominal organs	0.004	0.996	0.000
S36.6 Injury of rectum	0.004	0.996	0.000
S36.5 Injury of colon	0.004	0.996	0.000
S36.3 Injury of stomach	0.004	0.996	0.000
S36.2 Injury of pancreas	0.004	0.996	0.000
S11.2 Open wound involving pharynx and cervical oesophagus	0.004	0.996	0.000
S11.1 Open wound involving thyroid gland	0.004	0.996	0.000
S11.0 Open wound involving larynx and trachea	0.004	0.996	0.000
S30.1 Contusion of abdominal wall	0.004	0.996	0.000
Z49 Care involving dialysis	0.004	0.996	0.000
S12.71 Multiple fractures of cervical spine (open)	0.004	0.996	0.000
S37.3 Injury of urethra	0.004	0.996	0.000
T09.8 Other specified injuries of trunk, level unspecified	0.004	0.996	0.000
T09.6 Traumatic amputation of trunk, level unspecified	0.004	0.996	0.000
T09.5 Injury of unspecified muscle and tendon of trunk	0.004	0.996	0.000
T09.4 Injury of unspecified nerve, spinal nerve root and plexus of trunk	0.004	0.996	0.000
T09.1 Open wound of trunk, level unspecified	0.004	0.996	0.000
T93.2 Sequelae of other fractures of lower limb	0.004	0.996	0.000
S12.91 Fracture of neck, part unspecified (open)	0.004	0.996	0.000
T01.8 Open wounds involving other combinations of body regions	0.004	0.996	0.000
T13.8 Other specified injuries of lower limb, level unspecified	0.004	0.996	0.000
T13.6 Traumatic amputation of lower limb, level unspecified	0.004	0.996	0.000
T13.5 Injury of unspecified muscle and tendon of lower limb, level unspecified	0.004	0.996	0.000
T13.4 Injury of unspecified blood vessel of lower limb, level unspecified	0.004	0.996	0.000
T13.3 Injury of unspecified nerve of lower limb, level unspecified	0.004	0.996	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.004	0.996	0.000
S36.4 Injury of small intestine	0.004	0.996	0.000
T01.2 Open wounds involving multiple regions of upper limb(s)	0.004	0.996	0.000
T11.9 Unspecified injury of upper limb, level unspecified	0.004	0.996	0.000
T11.8 Other specified injuries of upper limb, level unspecified	0.004	0.996	0.000
T11.6 Traumatic amputation of upper limb, level unspecified	0.004	0.996	0.000
T11.5 Injury of unspecified muscle and tendon of upper limb, level unspecified	0.004	0.996	0.000
T11.4 Injury of unspecified blood vessel of upper limb, level unspecified	0.004	0.996	0.000
T11.3 Injury of unspecified nerve of upper limb, level unspecified	0.004	0.996	0.000
T11.2 Dislocation, strain and sprain of unspecified joint and ligament of upper limb, level unspecified	0.004	0.996	0.000
M79.18 Myalgia (Other)	0.004	0.996	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.000	0.996	0.004
T13.9 Unspecified injury of lower limb, level unspecified	0.004	0.996	0.000
T95.0 Sequelae of burn, corrosion and frostbite of head and neck	0.004	0.996	0.000
S12.81 Fracture of other parts of neck (open)	0.004	0.996	0.000
S12.80 Fracture of other parts of neck (closed)	0.004	0.996	0.000
T14.21 Fracture of unspecified body region (open)	0.004	0.996	0.000
T14.20 Fracture of unspecified body region (closed)	0.004	0.996	0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.004	0.996	0.000
T22.7 Corrosion of third degree of shoulder and upper limb, except wrist and hand	0.004	0.996	0.000
T22.6 Corrosion of second degree of shoulder and upper limb, except wrist and hand	0.004	0.996	0.000
T22.5 Corrosion of first degree of shoulder and upper limb, except wrist and hand	0.004	0.996	0.000
T22.4 Corrosion of unspecified degree of shoulder and upper limb, except wrist and hand	0.004	0.996	0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.004	0.996	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.004	0.996	0.000
S36.0 Injury of spleen	0.004	0.996	0.000
T13.1 Open wound of lower limb, level unspecified	0.004	0.996	0.000
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.004	0.996	0.000
S37.8 Injury of other pelvic organs	0.004	0.996	0.000
S37.7 Injury of multiple pelvic organs	0.004	0.996	0.000
S37.6 Injury of uterus	0.004	0.996	0.000
S37.5 Injury of Fallopian tube	0.004	0.996	0.000
S37.4 Injury of ovary	0.004	0.996	0.000
S37.1 Injury of ureter	0.004	0.996	0.000
T01.3 Open wounds involving multiple regions of lower limb(s)	0.004	0.996	0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.004	0.996	0.000
S27.41 Injury of bronchus (with open wound into thoracic cavity)	0.004	0.996	0.000
S27.40 Injury of bronchus (without open wound into thoracic cavity)	0.004	0.996	0.000
S27.51 Injury of thoracic trachea (with open wound into thoracic cavity)	0.004	0.996	0.000
S27.50 Injury of thoracic trachea (without open wound into thoracic cavity)	0.004	0.996	0.000
S27.61 Injury of pleura (with open wound into thoracic cavity)	0.004	0.996	0.000
S27.60 Injury of pleura (without open wound into thoracic cavity)	0.004	0.996	0.000
S27.71 Multiple injuries of intrathoracic organs (with open wound into thoracic cavity)	0.004	0.996	0.000
S27.70 Multiple injuries of intrathoracic organs (without open wound into thoracic cavity)	0.004	0.996	0.000
S27.91 Injury of unspecified intrathoracic organ (with open wound into thoracic cavity)	0.004	0.996	0.000
S27.90 Injury of unspecified intrathoracic organ (without open wound into thoracic cavity)	0.004	0.996	0.000
S39.7 Other multiple injuries of abdomen, lower back and pelvis	0.004	0.996	0.000
S39.6 Injury of intra-abdominal organ(s) with pelvic organ(s)	0.004	0.996	0.000
T95.2 Sequelae of burn, corrosion and frostbite of upper limb	0.004	0.996	0.000
H80-H83 Diseases of inner ear	0.004	0.996	0.000
T09.3 Injury of spinal cord, level unspecified	0.004	0.996	0.000
T22.1 Burn of first degree of shoulder and upper limb, except wrist and hand	0.004	0.996	0.000
T28 Burn and corrosion of other internal organs	0.004	0.996	0.000
T27 Burn and corrosion of respiratory tract	0.004	0.996	0.000
T79.2 Traumatic secondary and recurrent haemorrhage	0.004	0.996	0.000
T92.0 Sequelae of open wound of upper limb	0.004	0.996	0.000
S26.01 Injury of heart with haemopericardium (with open wound into thoracic cavity)	0.004	0.996	0.000
S26.00 Injury of heart with haemopericardium (without open wound into thoracic cavity)	0.004	0.996	0.000
S26.81 Other injuries of heart (with open wound into thoracic cavity)	0.004	0.996	0.000
S26.80 Other injuries of heart (without open wound into thoracic cavity)	0.004	0.996	0.000
S26.91 Injury of heart, unspecified (with open wound into thoracic cavity)	0.004	0.996	0.000
S26.90 Injury of heart, unspecified (without open wound into thoracic cavity)	0.004	0.996	0.000
K52.8 Other specified non-infective gastro-enteritis and colitis	0.000	0.996	0.004
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot	0.004	0.996	0.000
S27.81 Injury of other specified intrathoracic organs (with open wound into thoracic cavity)	0.004	0.996	0.000
S37.9 Injury of unspecified pelvic organ	0.004	0.996	0.000
T95.1 Sequelae of burn, corrosion and frostbite of trunk	0.004	0.996	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.004	0.996	0.000
S27.11 Traumatic haemothorax (with open wound into thoracic cavity)	0.004	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations