TreeWAS – Variant ID: rs715170

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.098	0.902	0.000
C01 Malignant neoplasm of base of tongue	0.098	0.902	0.000
C09 Malignant neoplasm of tonsil	0.096	0.904	0.000
C09.9 Tonsil, unspecified	0.096	0.904	0.000
C05 Malignant neoplasm of palate	0.082	0.918	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.080	0.920	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.079	0.921	0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.078	0.922	0.000
C07 Malignant neoplasm of parotid gland	0.078	0.922	0.000
C11 Malignant neoplasm of nasopharynx	0.076	0.924	0.000
C04 Malignant neoplasm of floor of mouth	0.075	0.925	0.000
C12 Malignant neoplasm of pyriform sinus	0.074	0.926	0.000
C10 Malignant neoplasm of oropharynx	0.073	0.927	0.000
C13 Malignant neoplasm of hypopharynx	0.071	0.929	0.000
C09.8 Overlapping lesion of tonsil	0.069	0.931	0.000
C09.1 Tonsillar pillar (anterior) (posterior)	0.069	0.931	0.000
C09.0 Tonsillar fossa	0.069	0.931	0.000
C05.9 Palate, unspecified	0.068	0.932	0.000
C02.9 Tongue, unspecified	0.068	0.932	0.000
C08.9 Major salivary gland, unspecified	0.067	0.933	0.000
C03 Malignant neoplasm of gum	0.066	0.934	0.000
C02.4 Lingual tonsil	0.066	0.934	0.000
C00 Malignant neoplasm of lip	0.064	0.936	0.000
C14.0 Pharynx, unspecified	0.064	0.936	0.000
C05.1 Soft palate	0.064	0.936	0.000
C11.1 Posterior wall of nasopharynx	0.063	0.937	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.062	0.938	0.000
C05.8 Overlapping lesion of palate	0.059	0.941	0.000
C05.2 Uvula	0.059	0.941	0.000
C05.0 Hard palate	0.059	0.941	0.000
C08.8 Overlapping lesion of major salivary glands	0.058	0.942	0.000
C08.1 Sublingual gland	0.058	0.942	0.000
C08.0 Submandibular gland	0.058	0.942	0.000
C04.9 Floor of mouth, unspecified	0.057	0.943	0.000
C02.8 Overlapping lesion of tongue	0.057	0.943	0.000
C02.3 Anterior two-thirds of tongue, part unspecified	0.057	0.943	0.000
C02.2 Ventral surface of tongue	0.057	0.943	0.000
C02.0 Dorsal surface of tongue	0.057	0.943	0.000
C04.0 Anterior floor of mouth	0.056	0.943	0.000
C14.8 Overlapping lesion of lip, oral cavity and pharynx	0.056	0.944	0.000
C14.2 Waldeyer's ring	0.056	0.944	0.000
C10.9 Oropharynx, unspecified	0.055	0.945	0.000
C11.8 Overlapping lesion of nasopharynx	0.055	0.945	0.000
C11.3 Anterior wall of nasopharynx	0.055	0.945	0.000
C11.2 Lateral wall of nasopharynx	0.055	0.945	0.000
C11.0 Superior wall of nasopharynx	0.055	0.945	0.000
C04.8 Overlapping lesion of floor of mouth	0.054	0.946	0.000
C04.1 Lateral floor of mouth	0.054	0.946	0.000
C10.8 Overlapping lesion of oropharynx	0.052	0.947	0.000
C10.4 Branchial cleft	0.052	0.947	0.000
C10.3 Posterior wall of oropharynx	0.052	0.947	0.000
C10.2 Lateral wall of oropharynx	0.052	0.947	0.000
C10.1 Anterior surface of epiglottis	0.052	0.947	0.000
C10.0 Vallecula	0.052	0.947	0.000
C13.9 Hypopharynx, unspecified	0.052	0.948	0.000
C13.8 Overlapping lesion of hypopharynx	0.051	0.949	0.000
C13.2 Posterior wall of hypopharynx	0.051	0.949	0.000
C13.1 Aryepiglottic fold, hypopharyngeal aspect	0.051	0.949	0.000
C13.0 Postcricoid region	0.051	0.949	0.000
C11.9 Nasopharynx, unspecified	0.051	0.949	0.000
C03.9 Gum, unspecified	0.047	0.952	0.000
C03.0 Upper gum	0.047	0.952	0.000
C00.1 External lower lip	0.047	0.952	0.000
C00.9 Lip, unspecified	0.046	0.954	0.000
C00.8 Overlapping lesion of lip	0.046	0.954	0.000
C00.6 Commissure of lip	0.046	0.954	0.000
C00.5 Lip, unspecified, inner aspect	0.046	0.954	0.000
C00.4 Lower lip, inner aspect	0.046	0.954	0.000
C00.3 Upper lip, inner aspect	0.046	0.954	0.000
C00.2 External lip, unspecified	0.046	0.954	0.000
C06.8 Overlapping lesion of other and unspecified parts of mouth	0.045	0.955	0.000
C06.1 Vestibule of mouth	0.045	0.955	0.000
C06.2 Retromolar area	0.045	0.955	0.000
C03.1 Lower gum	0.043	0.957	0.000
C06.9 Mouth, unspecified	0.042	0.957	0.000
C06.0 Cheek mucosa	0.040	0.960	0.000
C00.0 External upper lip	0.037	0.962	0.000
C02.1 Border of tongue	0.036	0.964	0.000
Q61.2 Polycystic kidney, adult type	0.000	0.965	0.035
Q61 Cystic kidney disease	0.000	0.966	0.034
Q61.3 Polycystic kidney, unspecified	0.000	0.966	0.034
Q61.5 Medullary cystic kidney	0.000	0.970	0.029
Q61.9 Cystic kidney disease, unspecified	0.000	0.973	0.027
Q61.0 Congenital single renal cyst	0.000	0.975	0.025
Q61.8 Other cystic kidney diseases	0.000	0.975	0.024
Q61.1 Polycystic kidney, infantile type	0.000	0.975	0.024
Q61.4 Renal dysplasia	0.000	0.977	0.022
Q60-Q64 Congenital malformations of the urinary system	0.000	0.990	0.010
N31.8 Other neuromuscular dysfunction of bladder	0.000	0.990	0.010
M25.86 Other specified joint disorders (Lower leg)	0.009	0.991	0.000
Q63 Other congenital malformations of kidney	0.000	0.992	0.008
Q63.1 Lobulated, fused and horseshoe kidney	0.000	0.993	0.007
Q64 Other congenital malformations of urinary system	0.000	0.993	0.007
Q63.2 Ectopic kidney	0.000	0.993	0.007
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.000	0.993	0.006
Q63.9 Congenital malformation of kidney, unspecified	0.000	0.994	0.006
Q63.8 Other specified congenital malformations of kidney	0.000	0.994	0.006
Q63.3 Hyperplastic and giant kidney	0.000	0.994	0.006
C81.9 Hodgkin's disease, unspecified	0.006	0.994	0.000
G03.9 Meningitis, unspecified	0.006	0.994	0.000
K60.2 Anal fissure, unspecified	0.000	0.994	0.006
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.000	0.994	0.006
G44.2 Tension-type headache	0.006	0.994	0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.000	0.994	0.006
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.995	0.005
Q63.0 Accessory kidney	0.000	0.995	0.005
Q64.9 Congenital malformation of urinary system, unspecified	0.000	0.995	0.005
Q64.8 Other specified congenital malformations of urinary system	0.000	0.995	0.005
Q64.6 Congenital diverticulum of bladder	0.000	0.995	0.005
Q64.5 Congenital absence of bladder and urethra	0.000	0.995	0.005
Q64.4 Malformation of urachus	0.000	0.995	0.005
Q64.2 Congenital posterior urethral valves	0.000	0.995	0.005
Q64.1 Exstrophy of urinary bladder	0.000	0.995	0.005
Q64.0 Epispadias	0.000	0.995	0.005
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.000	0.995	0.005
Q60 Renal agenesis and other reduction defects of kidney	0.000	0.995	0.005
Q62.8 Other congenital malformations of ureter	0.000	0.995	0.005
Q62.7 Congenital vesico-uretero-renal reflux	0.000	0.995	0.005
Q62.6 Malposition of ureter	0.000	0.995	0.005
Q62.4 Agenesis of ureter	0.000	0.995	0.005
Q62.3 Other obstructive defects of renal pelvis and ureter	0.000	0.995	0.005
Q62.2 Congenital megaloureter	0.000	0.995	0.005
Q62.1 Atresia and stenosis of ureter	0.000	0.995	0.005
Q62.0 Congenital hydronephrosis	0.000	0.995	0.005
N31.1 Reflex neuropathic bladder, not elsewhere classified	0.000	0.995	0.004
Q64.7 Other congenital malformations of bladder and urethra	0.000	0.995	0.004
N31.0 Uninhibited neuropathic bladder, not elsewhere classified	0.000	0.996	0.004
F31 Bipolar affective disorder	0.000	0.996	0.004
Q62.5 Duplication of ureter	0.000	0.996	0.004
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.996	0.004
Q60.6 Potter's syndrome	0.000	0.996	0.004
Q60.5 Renal hypoplasia, unspecified	0.000	0.996	0.004
Q60.4 Renal hypoplasia, bilateral	0.000	0.996	0.004
Q60.1 Renal agenesis, bilateral	0.000	0.996	0.004
T18.1 Foreign body in oesophagus	0.000	0.996	0.004
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.996	0.004
S90.8 Other superficial injuries of ankle and foot	0.004	0.996	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.996	0.004
S90.9 Superficial injury of ankle and foot, unspecified	0.004	0.996	0.000
F31.9 Bipolar affective disorder, unspecified	0.000	0.996	0.004
D80.1 Nonfamilial hypogammaglobulinaemia	0.000	0.996	0.004
Q60.3 Renal hypoplasia, unilateral	0.000	0.996	0.003
G03 Meningitis due to other and unspecified causes	0.003	0.997	0.000
M25.8 Other specified joint disorders	0.003	0.997	0.000
C32.9 Larynx, unspecified	0.000	0.997	0.003
J32.0 Chronic maxillary sinusitis	0.000	0.997	0.003
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.997	0.003
Q60.2 Renal agenesis, unspecified	0.000	0.997	0.003
F31.8 Other bipolar affective disorders	0.000	0.997	0.003
D12.5 Sigmoid colon	0.000	0.997	0.003
S90 Superficial injury of ankle and foot	0.003	0.997	0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified	0.000	0.997	0.003
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.997	0.003
F31.7 Bipolar affective disorder, currently in remission	0.000	0.997	0.003
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.003	0.997	0.000
C81 Hodgkin's disease	0.003	0.997	0.000
Q60.0 Renal agenesis, unilateral	0.000	0.997	0.003
M79.89 Other specified soft tissue disorders (Site unspecified)	0.003	0.997	0.000
N39.9 Disorder of urinary system, unspecified	0.003	0.997	0.000
J98.1 Pulmonary collapse	0.003	0.997	0.000
H59.8 Other postprocedural disorders of eye and adnexa	0.000	0.997	0.003
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.003	0.997	0.000
K74.6 Other and unspecified cirrhosis of liver	0.000	0.997	0.003
T91.1 Sequelae of fracture of spine	0.003	0.997	0.000
M25.83 Other specified joint disorders (Forearm)	0.003	0.997	0.000
D32.9 Meninges, unspecified	0.000	0.997	0.003
C81.7 Other Hodgkin's disease	0.003	0.997	0.000
S93.1 Dislocation of toe(s)	0.003	0.997	0.000
G03.8 Meningitis due to other specified causes	0.003	0.997	0.000
G03.2 Benign recurrent meningitis [Mollaret]	0.003	0.997	0.000
G03.1 Chronic meningitis	0.003	0.997	0.000
G03.0 Nonpyogenic meningitis	0.003	0.997	0.000
M25.89 Other specified joint disorders (Site unspecified)	0.003	0.997	0.000
M25.82 Other specified joint disorders (Upper arm)	0.003	0.997	0.000
M25.80 Other specified joint disorders (Multiple sites)	0.003	0.997	0.000
O26.8 Other specified pregnancy-related conditions	0.000	0.997	0.003
S90.1 Contusion of toe(s) without damage to nail	0.003	0.997	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.003	0.997	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.002	0.997	0.000
S90.2 Contusion of toe(s) with damage to nail	0.002	0.997	0.000
M25.84 Other specified joint disorders (Hand)	0.003	0.997	0.000
T86.1 Kidney transplant failure and rejection	0.003	0.997	0.000
C32 Malignant neoplasm of larynx	0.000	0.997	0.003
M79.46 Hypertrophy of (infrapatellar) fat pad (Lower leg)	0.003	0.997	0.000
C81.0 Lymphocytic predominance	0.003	0.997	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.002	0.997	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.997	0.002
S29.9 Unspecified injury of thorax	0.003	0.997	0.000
D80 Immunodeficiency with predominantly antibody defects	0.000	0.997	0.003
M25.88 Other specified joint disorders (Other)	0.002	0.997	0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.002	0.997	0.000
C81.3 Lymphocytic depletion	0.002	0.997	0.000
C81.2 Mixed cellularity	0.002	0.997	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.002	0.997	0.000
T91.9 Sequelae of unspecified injury of neck and trunk	0.002	0.997	0.000
D32.0 Cerebral meninges	0.000	0.998	0.002
S21.1 Open wound of front wall of thorax	0.002	0.998	0.000
S93.0 Dislocation of ankle joint	0.002	0.998	0.000
S21.9 Open wound of thorax, part unspecified	0.002	0.998	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.000	0.998	0.002
N71.1 Chronic inflammatory disease of uterus	0.002	0.998	0.000
S21 Open wound of thorax	0.002	0.998	0.000
D21.2 Connective and other soft tissue of lower limb, including hip	0.000	0.998	0.002
C32.0 Glottis	0.000	0.998	0.002
C81.1 Nodular sclerosis	0.002	0.998	0.000
S93.4 Sprain and strain of ankle	0.002	0.998	0.000
S93.5 Sprain and strain of toe(s)	0.002	0.998	0.000
T18 Foreign body in alimentary tract	0.000	0.998	0.002
Q43.0 Meckel's diverticulum	0.002	0.998	0.000
K60 Fissure and fistula of anal and rectal regions	0.000	0.998	0.002
M25.87 Other specified joint disorders (Ankle and foot)	0.002	0.998	0.000
M25.81 Other specified joint disorders (Shoulder region)	0.002	0.998	0.000
S21.2 Open wound of back wall of thorax	0.002	0.998	0.000
O21.0 Mild hyperemesis gravidarum	0.000	0.998	0.002
S90-S99 Injuries to the ankle and foot	0.002	0.998	0.000
G44 Other headache syndromes	0.002	0.998	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.000	0.998	0.002
S90.3 Contusion of other and unspecified parts of foot	0.002	0.998	0.000
T91 Sequelae of injuries of neck and trunk	0.002	0.998	0.000
H02.6 Xanthelasma of eyelid	0.002	0.998	0.000
C32.8 Overlapping lesion of larynx	0.000	0.998	0.002
C32.3 Laryngeal cartilage	0.000	0.998	0.002
C32.2 Subglottis	0.000	0.998	0.002
M79.09 Rheumatism, unspecified (Site unspecified)	0.002	0.998	0.000
S29 Other and unspecified injuries of thorax	0.002	0.998	0.000
K60.1 Chronic anal fissure	0.000	0.998	0.002
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.000	0.998	0.002
D80.8 Other immunodeficiencies with predominantly antibody defects	0.000	0.998	0.002
D80.7 Transient hypogammaglobulinaemia of infancy	0.000	0.998	0.002
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.000	0.998	0.002
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.000	0.998	0.002
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.000	0.998	0.002
D80.0 Hereditary hypogammaglobulinaemia	0.000	0.998	0.002
S90.0 Contusion of ankle	0.002	0.998	0.000
T18.9 Foreign body in alimentary tract, part unspecified	0.000	0.998	0.002
C32.1 Supraglottis	0.000	0.998	0.002
G06.0 Intracranial abscess and granuloma	0.002	0.998	0.000
G44.1 Vascular headache, not elsewhere classified	0.002	0.998	0.000
M79.4 Hypertrophy of (infrapatellar) fat pad	0.002	0.998	0.000
T18.5 Foreign body in anus and rectum	0.000	0.998	0.002
S99 Other and unspecified injuries of ankle and foot	0.002	0.998	0.000
K60.4 Rectal fistula	0.000	0.998	0.002
S99.8 Other specified injuries of ankle and foot	0.002	0.998	0.000
H57.9 Disorder of eye and adnexa, unspecified	0.002	0.998	0.000
I86.1 Scrotal varices	0.002	0.998	0.000
O21.2 Late vomiting of pregnancy	0.000	0.998	0.002
S21.8 Open wound of other parts of thorax	0.002	0.998	0.000
S21.7 Multiple open wounds of thoracic wall	0.002	0.998	0.000
S21.0 Open wound of breast	0.002	0.998	0.000
S97 Crushing injury of ankle and foot	0.002	0.998	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.000	0.998	0.002
S93.40 Sprain of unspecified ligament of ankle	0.002	0.998	0.000
K60.0 Acute anal fissure	0.000	0.998	0.002
O21.9 Vomiting of pregnancy, unspecified	0.000	0.998	0.002
T18.8 Foreign body in other and multiple parts of alimentary tract	0.000	0.998	0.002
T18.4 Foreign body in colon	0.000	0.998	0.002
T18.3 Foreign body in small intestine	0.000	0.998	0.002
T18.2 Foreign body in stomach	0.000	0.998	0.002
D32 Benign neoplasm of meninges	0.000	0.998	0.002
D23.1 Skin of eyelid, including canthus	0.002	0.998	0.000
S29.8 Other specified injuries of thorax	0.002	0.998	0.000
T91.2 Sequelae of other fracture of thorax and pelvis	0.002	0.998	0.000
O21 Excessive vomiting in pregnancy	0.000	0.998	0.002
M43.17 Spondylolisthesis (Lumbosacral region)	0.002	0.998	0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.000	0.998	0.002
D47.2 Monoclonal gammopathy	0.002	0.998	0.000
O47.0 False labour before 37 completed weeks of gestation	0.000	0.998	0.002
T91.8 Sequelae of other specified injuries of neck and trunk	0.002	0.998	0.000
S98 Traumatic amputation of ankle and foot	0.002	0.998	0.000
S95 Injury of blood vessels at ankle and foot level	0.002	0.998	0.000
S94 Injury of nerves at ankle and foot level	0.002	0.998	0.000
G58.7 Mononeuritis multiplex	0.002	0.998	0.000
Z03.1 Observation for suspected malignant neoplasm	0.002	0.998	0.000
M79.97 Soft tissue disorder, unspecified (Ankle and foot)	0.002	0.998	0.000
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.002	0.998	0.000
T91.4 Sequelae of injury of intrathoracic organs	0.002	0.998	0.000
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.002	0.998	0.000
G06 Intracranial and intraspinal abscess and granuloma	0.002	0.998	0.000
S29.0 Injury of muscle and tendon at thorax level	0.002	0.998	0.000
D44.0 Thyroid gland	0.002	0.998	0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.002	0.998	0.000
Z43.1 Attention to gastrostomy	0.002	0.998	0.000
G44.8 Other specified headache syndromes	0.002	0.998	0.000
G44.4 Drug-induced headache, not elsewhere classified	0.002	0.998	0.000
M79.2 Neuralgia and neuritis, unspecified	0.002	0.998	0.000
S29.7 Multiple injuries of thorax	0.002	0.998	0.000
C18.7 Sigmoid colon	0.002	0.998	0.000
G44.3 Chronic posttraumatic headache	0.002	0.998	0.000
G44.0 Cluster headache syndrome	0.002	0.998	0.000
S97.1 Crushing injury of toe(s)	0.002	0.998	0.000
M49.54 Collapsed vertebra in diseases classified elsewhere (Thoracic region)	0.002	0.998	0.000
M79.10 Myalgia (Multiple sites)	0.002	0.998	0.000
T18.0 Foreign body in mouth	0.000	0.998	0.002
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.002	0.998	0.000
T39.0 Salicylates	0.002	0.998	0.000
S92 Fracture of foot, except ankle	0.002	0.998	0.000
M79.20 Neuralgia and neuritis, unspecified (Multiple sites)	0.002	0.998	0.000
M79.49 Hypertrophy of (infrapatellar) fat pad-Site unspec	0.002	0.998	0.000
M79.48 Hypertrophy of (infrapatellar) fat pad (Other)	0.002	0.998	0.000
M79.47 Hypertrophy of (infrapatellar) fat pad (Ankle and foot)	0.002	0.998	0.000
M79.45 Hypertrophy of (infrapatellar) fat pad (Pelvic region and thigh)	0.002	0.998	0.000
M79.44 Hypertrophy of (infrapatellar) fat pad (Hand)	0.002	0.998	0.000
M79.43 Hypertrophy of (infrapatellar) fat pad (Forearm)	0.002	0.998	0.000
M79.42 Hypertrophy of (infrapatellar) fat pad (Upper arm)	0.002	0.998	0.000
M79.41 Hypertrophy of (infrapatellar) fat pad (Shoulder region)	0.002	0.998	0.000
M79.40 Hypertrophy of (infrapatellar) fat pad (Multiple sites)	0.002	0.998	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.000	0.998	0.002
S99.7 Multiple injuries of ankle and foot	0.002	0.998	0.000
M79.26 Neuralgia and neuritis, unspecified (Lower leg)	0.002	0.998	0.000
M79.80 Other specified soft tissue disorders (Multiple sites)	0.002	0.998	0.000
T86.8 Failure and rejection of other transplanted organs and tissues	0.002	0.998	0.000
M79.23 Neuralgia and neuritis, unspecified (Forearm)	0.002	0.998	0.000
S92.7 Multiple fractures of foot	0.002	0.998	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.002	0.998	0.000
S97.0 Crushing injury of ankle	0.002	0.998	0.000
S92.70 Multiple fractures of foot (closed)	0.002	0.998	0.000
M79.9 Soft tissue disorder, unspecified	0.002	0.998	0.000
M79.0 Rheumatism, unspecified	0.002	0.998	0.000
K70.9 Alcoholic liver disease, unspecified	0.000	0.998	0.002
K70.1 Alcoholic hepatitis	0.000	0.998	0.002
S92.9 Fracture of foot, unspecified	0.002	0.998	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.002	0.998	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.000	0.998	0.002
M79.28 Neuralgia and neuritis, unspecified (Other)	0.002	0.998	0.000
K60.5 Anorectal fistula	0.000	0.998	0.002
R00.0 Tachycardia, unspecified	0.002	0.998	0.000
Z36.0 Antenatal screening for chromosomal anomalies	0.002	0.998	0.000
S22.20 Fracture of sternum (closed)	0.002	0.998	0.000
S92.90 Fracture of foot, unspecified (closed)	0.002	0.998	0.000
G06.1 Intraspinal abscess and granuloma	0.002	0.998	0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.000	0.998	0.002
S94.9 Injury of unspecified nerve at ankle and foot level	0.001	0.998	0.000
S94.8 Injury of other nerves at ankle and foot level	0.001	0.998	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.001	0.998	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.001	0.998	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.001	0.998	0.000
S94.1 Injury of medial plantar nerve	0.001	0.998	0.000
S94.0 Injury of lateral plantar nerve	0.001	0.998	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.001	0.998	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.001	0.998	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.001	0.998	0.000
S95.2 Injury of dorsal vein of foot	0.001	0.998	0.000
S95.1 Injury of plantar artery of foot	0.001	0.998	0.000
S95.0 Injury of dorsal artery of foot	0.001	0.998	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.001	0.998	0.000
S98.3 Traumatic amputation of other parts of foot	0.001	0.998	0.000
S98.2 Traumatic amputation of two or more toes	0.001	0.998	0.000
S98.1 Traumatic amputation of one toe	0.001	0.998	0.000
S98.0 Traumatic amputation of foot at ankle level	0.001	0.998	0.000
Z89.5 Acquired absence of leg at or below knee	0.000	0.998	0.002
T86 Failure and rejection of transplanted organs and tissues	0.002	0.998	0.000
M79.95 Soft tissue disorder, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.002	0.998	0.000
M79.98 Soft tissue disorder, unspecified (Other)	0.002	0.998	0.000
S22.30 Fracture of rib (closed)	0.002	0.998	0.000
K70.3 Alcoholic cirrhosis of liver	0.000	0.998	0.002
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.000	0.998	0.002
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)	0.002	0.998	0.000
S92.40 Fracture of great toe (closed)	0.002	0.998	0.000
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere	0.002	0.998	0.000
S92.4 Fracture of great toe	0.002	0.998	0.000
M79 Other soft tissue disorders, not elsewhere classified	0.002	0.998	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.002	0.998	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.000	0.998	0.002
G58.8 Other specified mononeuropathies	0.002	0.998	0.000
C37 Malignant neoplasm of thymus	0.000	0.998	0.002
S91 Open wound of ankle and foot	0.002	0.998	0.000
M79.24 Neuralgia and neuritis, unspecified (Hand)	0.001	0.998	0.000
M79.22 Neuralgia and neuritis, unspecified (Upper arm)	0.001	0.998	0.000
M79.21 Neuralgia and neuritis, unspecified (Shoulder region)	0.001	0.998	0.000
O44.0 Placenta praevia specified as without haemorrhage	0.000	0.998	0.002
S92.2 Fracture of other tarsal bone(s)	0.001	0.998	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.000	0.998	0.002
S20-S29 Injuries to the thorax	0.002	0.998	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.002	0.998	0.000
C30 Malignant neoplasm of nasal cavity and middle ear	0.000	0.998	0.001
C34.2 Middle lobe, bronchus or lung	0.000	0.998	0.002
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.000	0.998	0.001
M79.94 Soft tissue disorder, unspecified (Hand)	0.001	0.998	0.000
M81.98 Osteoporosis, unspecified (Other)	0.000	0.998	0.002
G06.2 Extradural and subdural abscess, unspecified	0.001	0.998	0.000
G58.9 Mononeuropathy, unspecified	0.002	0.998	0.000
M79.8 Other specified soft tissue disorders	0.002	0.998	0.000
N71.9 Inflammatory disease of uterus, unspecified	0.002	0.998	0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.000	0.998	0.001
S99.9 Unspecified injury of ankle and foot	0.001	0.998	0.000
G00 Bacterial meningitis, not elsewhere classified	0.001	0.998	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.001	0.998	0.000
C30.0 Nasal cavity	0.000	0.998	0.001
O26.9 Pregnancy-related condition, unspecified	0.000	0.998	0.002
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.000	0.998	0.001
T86.4 Liver transplant failure and rejection	0.001	0.998	0.000
N71 Inflammatory disease of uterus, except cervix	0.002	0.998	0.000
M40.56 Lordosis, unspecified (Lumbar region)	0.001	0.998	0.000
M79.07 Rheumatism, unspecified (Ankle and foot)	0.001	0.998	0.000
M79.06 Rheumatism, unspecified (Lower leg)	0.001	0.998	0.000
M79.05 Rheumatism, unspecified (Pelvic region and thigh)	0.001	0.998	0.000
M79.04 Rheumatism, unspecified (Hand)	0.001	0.998	0.000
M79.03 Rheumatism, unspecified (Forearm)	0.001	0.998	0.000
M79.02 Rheumatism, unspecified (Upper arm)	0.001	0.998	0.000
M79.01 Rheumatism, unspecified (Shoulder region)	0.001	0.998	0.000
M79.93 Soft tissue disorder, unspecified (Forearm)	0.001	0.998	0.000
M79.92 Soft tissue disorder, unspecified (Upper arm)	0.001	0.998	0.000
M79.91 Soft tissue disorder, unspecified (Shoulder region)	0.001	0.998	0.000
M79.90 Soft tissue disorder, unspecified (Multiple sites)	0.001	0.998	0.000
S92.71 Multiple fractures of foot (open)	0.001	0.998	0.000
G00.1 Pneumococcal meningitis	0.001	0.998	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.000	0.998	0.002
T63.4 Venom of other arthropods	0.001	0.998	0.000
M79.27 Neuralgia and neuritis, unspecified (Ankle and foot)	0.001	0.998	0.000
S92.91 Fracture of foot, unspecified (open)	0.001	0.998	0.000
D17.6 Benign lipomatous neoplasm of spermatic cord	0.002	0.998	0.000
K12.3 Oral mucositis (ulcerative)	0.000	0.998	0.001
S22.2 Fracture of sternum	0.001	0.998	0.000
T91.3 Sequelae of injury of spinal cord	0.001	0.998	0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.001	0.998	0.000
C34.9 Bronchus or lung, unspecified	0.000	0.999	0.001
S22.3 Fracture of rib	0.001	0.999	0.000
S92.1 Fracture of talus	0.001	0.999	0.000
T86.9 Failure and rejection of unspecified transplanted organ and tissue	0.001	0.999	0.000
T86.3 Heart-lung transplant failure and rejection	0.001	0.999	0.000
T86.2 Heart transplant failure and rejection	0.001	0.999	0.000
G01 Meningitis in bacterial diseases classified elsewhere	0.001	0.999	0.000
D32.1 Spinal meninges	0.000	0.999	0.001
E80.4 Gilbert's syndrome	0.001	0.999	0.000
J37.0 Chronic laryngitis	0.001	0.999	0.000
G58 Other mononeuropathies	0.001	0.999	0.000
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere	0.001	0.999	0.000
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere	0.001	0.999	0.000
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere	0.001	0.999	0.000
N71.0 Acute inflammatory disease of uterus	0.001	0.999	0.000
O21.8 Other vomiting complicating pregnancy	0.000	0.999	0.001
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.000	0.999	0.001
C34 Malignant neoplasm of bronchus and lung	0.000	0.999	0.001
C31 Malignant neoplasm of accessory sinuses	0.000	0.999	0.001
C33 Malignant neoplasm of trachea	0.000	0.999	0.001
M79.58 Residual foreign body in soft tissue (Other)	0.001	0.999	0.000
M79.99 Soft tissue disorder, unspecified (Site unspecified)	0.001	0.999	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.001	0.999	0.000
F02.8 Dementia in other specified diseases classified elsewhere	0.000	0.999	0.001
M79.3 Panniculitis, unspecified	0.001	0.999	0.000
S27.2 Traumatic heamopneumothorax	0.001	0.999	0.001
T31.0 Burns involving less than 10% of body surface	0.000	0.999	0.001
M79.81 Other specified soft tissue disorders (Shoulder region)	0.001	0.999	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.001	0.999	0.000
O26.5 Maternal hypotension syndrome	0.000	0.999	0.001
O26.4 Herpes gestationis	0.000	0.999	0.001
O26.1 Low weight gain in pregnancy	0.000	0.999	0.001
S69.9 Unspecified injury of wrist and hand	0.001	0.999	0.000
S91.7 Multiple open wounds of ankle and foot	0.001	0.999	0.000
S91.3 Open wound of other parts of foot	0.001	0.999	0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.001	0.999	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.001	0.999	0.000
S26 Injury of heart	0.001	0.999	0.000
S25 Injury of blood vessels of thorax	0.001	0.999	0.000
S24 Injury of nerves and spinal cord at thorax level	0.001	0.999	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.001	0.999	0.000
M49.56 Collapsed vertebra in diseases classified elsewhere (Lumbar region)	0.001	0.999	0.000
M79.08 Rheumatism, unspecified (Other)	0.001	0.999	0.000
M79.25 Neuralgia and neuritis, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)	0.001	0.999	0.000
C30.1 Middle ear	0.000	0.999	0.001
G00.2 Streptococcal meningitis	0.001	0.999	0.000
H57.0 Anomalies of pupillary function	0.001	0.999	0.000
T86.0 Bone-marrow transplant rejection	0.001	0.999	0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods	0.001	0.999	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.000	0.999	0.001
M79.70 Fibromyalgia (Multiple sites)	0.001	0.999	0.000
G00.8 Other bacterial meningitis	0.001	0.999	0.000
G00.3 Staphylococcal meningitis	0.001	0.999	0.000
G00.0 Haemophilus meningitis	0.001	0.999	0.000
I37.1 Pulmonary valve insufficiency	0.000	0.999	0.001
M79.1 Myalgia	0.001	0.999	0.000
S91.2 Open wound of toe(s) with damage to nail	0.001	0.999	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.001	0.999	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.001	0.999	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.001	0.999	0.000
Q43 Other congenital malformations of intestine	0.001	0.999	0.000
M79.16 Myalgia (Lower leg)	0.001	0.999	0.000
K60.3 Anal fistula	0.000	0.999	0.001
M49.5 Collapsed vertebra in diseases classified elsewhere	0.001	0.999	0.000
C38 Malignant neoplasm of heart, mediastinum and pleura	0.000	0.999	0.001
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.000	0.999	0.001
S22.21 Fracture of sternum (open)	0.001	0.999	0.000
D05.0 Lobular carcinoma in situ	0.001	0.999	0.000
D44.3 Pituitary gland	0.001	0.999	0.000
M51.4 Schmorl's nodes	0.000	0.999	0.001
O26.0 Excessive weight gain in pregnancy	0.000	0.999	0.001
S20.4 Other superficial injuries of back wall of thorax	0.001	0.999	0.000
K70 Alcoholic liver disease	0.000	0.999	0.001
S22.31 Fracture of rib (open)	0.001	0.999	0.000
S92.11 Fracture of talus (open)	0.001	0.999	0.000
K55.9 Vascular disorder of intestine, unspecified	0.001	0.999	0.000
S92.0 Fracture of calcaneus	0.001	0.999	0.000
T92.4 Sequelae of injury of nerve of upper limb	0.001	0.999	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.001	0.999	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.000	0.999	0.001
G58.0 Intercostal neuropathy	0.001	0.999	0.000
M79.7 Fibromyalgia	0.001	0.999	0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations