TreeWAS – Variant ID: rs715299

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
E10.9 Without complications	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
E05.0 Thyrotoxicosis with diffuse goitre	1.000	0.000	0.000
E10.3 With ophthalmic complications	1.000	0.000	0.000
E03 Other hypothyroidism	1.000	0.000	0.000
E14 Unspecified diabetes mellitus	1.000	0.000	0.000
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
E10.1 With ketoacidosis	0.999	0.001	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.999	0.001	0.000
E16 Other disorders of pancreatic internal secretion	0.999	0.001	0.000
D64.9 Anaemia, unspecified	0.999	0.001	0.000
J45.9 Asthma, unspecified	0.999	0.001	0.000
E16.2 Hypoglycaemia, unspecified	0.998	0.002	0.000
D64 Other anaemias	0.994	0.006	0.000
E14.3 With ophthalmic complications	0.993	0.007	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.993	0.007	0.000
E11 Non-insulin-dependent diabetes mellitus	0.992	0.008	0.000
D60-D64 Aplastic and other anaemias	0.991	0.009	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.988	0.012	0.000
D50-D53 Nutritional anaemias	0.985	0.015	0.000
E14.9 Without complications	0.982	0.018	0.000
I74 Arterial embolism and thrombosis	0.982	0.018	0.000
I73 Other peripheral vascular diseases	0.971	0.029	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.971	0.029	0.000
D50 Iron deficiency anaemia	0.970	0.030	0.000
# Top node	0.968	0.032	0.000
I77 Other disorders of arteries and arterioles	0.966	0.034	0.000
D50.9 Iron deficiency anaemia, unspecified	0.964	0.036	0.000
E10.4 With neurological complications	0.956	0.044	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.955	0.045	0.000
G35 Multiple sclerosis	0.000	0.047	0.953
I77.1 Stricture of artery	0.948	0.052	0.000
E11.5 With peripheral circulatory complications	0.944	0.056	0.000
Chapter II Neoplasms	0.943	0.057	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.941	0.059	0.000
I71 Aortic aneurysm and dissection	0.937	0.063	0.000
D51 Vitamin B12 deficiency anaemia	0.936	0.064	0.000
I73.9 Peripheral vascular disease, unspecified	0.930	0.070	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.930	0.070	0.000
M05-M14 Inflammatory polyarthropathies	0.928	0.072	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.928	0.072	0.000
C15-C26 Malignant neoplasms of digestive organs	0.927	0.073	0.000
J45 Asthma	0.927	0.073	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.925	0.075	0.000
E11.1 With ketoacidosis	0.924	0.076	0.000
E10.2 With renal complications	0.924	0.076	0.000
M06.9 Rheumatoid arthritis, unspecified	0.923	0.077	0.000
C15 Malignant neoplasm of oesophagus	0.923	0.077	0.000
M06 Other rheumatoid arthritis	0.921	0.079	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.921	0.079	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.913	0.087	0.000
C85.1 B-cell lymphoma, unspecified	0.909	0.091	0.000
M50-M54 Other dorsopathies	0.907	0.093	0.000
M10 Gout	0.906	0.094	0.000
M51 Other intervertebral disk disorders	0.904	0.096	0.000
E11.9 Without complications	0.900	0.100	0.000
J40-J47 Chronic lower respiratory diseases	0.900	0.100	0.000
I72 Other aneurysm	0.899	0.101	0.000
M51.2 Other specified intervertebral disk displacement	0.899	0.101	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.892	0.108	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.892	0.108	0.000
E10.8 With unspecified complications	0.888	0.112	0.000
Chapter IX Diseases of the circulatory system	0.887	0.113	0.000
I73.0 Raynaud's syndrome	0.886	0.114	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.885	0.115	0.000
M10.9 Gout, unspecified	0.884	0.116	0.000
E14.1 With ketoacidosis	0.883	0.117	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.880	0.120	0.000
M70-M79 Other soft tissue disorders	0.879	0.121	0.000
M72 Fibroblastic disorders	0.876	0.124	0.000
Chapter X Diseases of the respiratory system	0.876	0.124	0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.876	0.124	0.000
C15.9 Oesophagus, unspecified	0.875	0.125	0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.874	0.126	0.000
J43 Emphysema	0.874	0.126	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.873	0.127	0.000
C15.4 Middle third of oesophagus	0.868	0.132	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.867	0.133	0.000
I72.4 Aneurysm of artery of lower extremity	0.864	0.136	0.000
M10.90 Gout, unspecified (Multiple sites)	0.859	0.141	0.000
J43.9 Emphysema, unspecified	0.858	0.142	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.857	0.143	0.000
M05 Seropositive rheumatoid arthritis	0.857	0.143	0.000
C91 Lymphoid leukaemia	0.852	0.148	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.847	0.153	0.000
Q60-Q64 Congenital malformations of the urinary system	0.847	0.153	0.000
J46 Status asthmaticus	0.843	0.157	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.842	0.158	0.000
I74.8 Embolism and thrombosis of other arteries	0.841	0.159	0.000
D00-D09 In situ neoplasms	0.840	0.160	0.000
Q50-Q56 Congenital malformations of genital organs	0.834	0.166	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.832	0.168	0.000
E10.0 With coma	0.832	0.168	0.000
E06 Thyroiditis	0.824	0.176	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.001	0.179	0.820
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.815	0.185	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.815	0.185	0.000
E14.2 Withrenal complications	0.812	0.188	0.000
Q43 Other congenital malformations of intestine	0.812	0.188	0.000
E14.8 With unspecified complications	0.808	0.192	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.807	0.193	0.000
C07 Malignant neoplasm of parotid gland	0.807	0.193	0.000
C32 Malignant neoplasm of larynx	0.806	0.194	0.000
M10.96 Gout, unspecified (Lower leg)	0.806	0.194	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.805	0.195	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.802	0.198	0.000
D80-D89 Certain disorders involving the immune mechanism	0.800	0.200	0.000
C22.9 Liver, unspecified	0.800	0.200	0.000
D53 Other nutritional anaemias	0.800	0.200	0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.798	0.202	0.000
Q39 Congenital malformations of oesophagus	0.798	0.202	0.000
C15.3 Upper third of oesophagus	0.797	0.203	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.794	0.206	0.000
E11.3 With ophthalmic complications	0.792	0.208	0.000
G37 Other demyelinating diseases of central nervous system	0.000	0.209	0.791
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.782	0.218	0.000
E40-E46 Malnutrition	0.777	0.223	0.000
C23 Malignant neoplasm of gallbladder	0.775	0.225	0.000
E11.8 With unspecified complications	0.775	0.225	0.000
E14.0 With coma	0.771	0.229	0.000
E16.1 Other hypoglycaemia	0.771	0.229	0.000
D07 Carcinoma in situ of other and unspecified genital organs	0.769	0.230	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.230	0.770
D50.1 Sideropenic dysphagia	0.763	0.237	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.761	0.239	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.761	0.239	0.000
C32.0 Glottis	0.760	0.240	0.000
C83.3 Large cell (diffuse)	0.759	0.241	0.000
C15.0 Cervical part of oesophagus	0.757	0.243	0.000
D64.8 Other specified anaemias	0.755	0.245	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.755	0.245	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.754	0.246	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.751	0.249	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.751	0.249	0.000
C91.1 Chronic lymphocytic leukaemia	0.748	0.252	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.748	0.252	0.000
C02.9 Tongue, unspecified	0.747	0.253	0.000
E10.7 With multiple complications	0.746	0.254	0.000
I71.0 Dissection of aorta [any part]	0.743	0.257	0.000
E03.1 Congenital hypothyroidism without goitre	0.742	0.258	0.000
C21 Malignant neoplasm of anus and anal canal	0.741	0.258	0.000
Q54 Hypospadias	0.741	0.259	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.741	0.259	0.000
J95-J99 Other diseases of the respiratory system	0.740	0.260	0.000
E14.4 With neurological complications	0.740	0.260	0.000
M10.94 Gout, unspecified (Hand)	0.739	0.261	0.000
E11.0 With coma	0.737	0.263	0.000
D07.1 Vulva	0.733	0.267	0.000
M05.8 Other seropositive rheumatoid arthritis	0.732	0.268	0.000
C13 Malignant neoplasm of hypopharynx	0.729	0.270	0.000
D62 Acute posthaemorrhagic anaemia	0.729	0.271	0.000
C84.8 Cutaneous T-cell lymphoma, unspecified	0.729	0.271	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.727	0.273	0.000
Q44.6 Cystic disease of liver	0.727	0.273	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.727	0.273	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.727	0.273	0.000
C15.1 Thoracic part of oesophagus	0.727	0.273	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.726	0.274	0.000
C86 Other specified types of T/NK-cell lymphoma	0.724	0.276	0.000
C22.0 Liver cell carcinoma	0.724	0.276	0.000
Q60.0 Renal agenesis, unilateral	0.724	0.276	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.723	0.277	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.721	0.279	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.719	0.281	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.718	0.282	0.000
E07 Other disorders of thyroid	0.717	0.282	0.000
M10.0 Idiopathic gout	0.717	0.283	0.000
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
E03.5 Myxoedema coma	0.717	0.283	0.000
E03.4 Atrophy of thyroid (acquired)	0.717	0.283	0.000
E03.3 Postinfectious hypothyroidism	0.717	0.283	0.000
E14.7 With multiple complications	0.717	0.283	0.000
E15 Nondiabetic hypoglycaemic coma	0.717	0.283	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.716	0.284	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.716	0.284	0.000
E16.4 Abnormal secretion of gastrin	0.716	0.284	0.000
E16.3 Increased secretion of glucagon	0.716	0.284	0.000
C16 Malignant neoplasm of stomach	0.715	0.285	0.000
E06.3 Autoimmune thyroiditis	0.713	0.287	0.000
D64.4 Congenital dyserythropoietic anaemia	0.713	0.287	0.000
D64.3 Other sideroblastic anaemias	0.713	0.287	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.713	0.287	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.713	0.287	0.000
D64.0 Hereditary sideroblastic anaemia	0.713	0.287	0.000
M51.3 Other specified intervertebral disk degeneration	0.712	0.288	0.000
E11.7 With multiple complications	0.711	0.288	0.000
Q45 Other congenital malformations of digestive system	0.711	0.288	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.711	0.289	0.000
C32.9 Larynx, unspecified	0.710	0.290	0.000
Q60.2 Renal agenesis, unspecified	0.710	0.290	0.000
M72.09 Palmar fascial fibromatosis [Dupuytren]-Site unspec	0.709	0.291	0.000
I77.0 Arteriovenous fistula, acquired	0.709	0.291	0.000
C81 Hodgkin's disease	0.707	0.292	0.000
I70 Atherosclerosis	0.707	0.293	0.000
E11.2 With renal complications	0.706	0.294	0.000
I10-I15 Hypertensive diseases	0.704	0.296	0.000
C04 Malignant neoplasm of floor of mouth	0.704	0.296	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.703	0.297	0.000
M51.9 Intervertebral disk disorder, unspecified	0.699	0.301	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.699	0.301	0.000
C50-C50 Malignant neoplasm of breast	0.697	0.303	0.000
C84.5 Other and unspecified T-cell lymphomas	0.696	0.304	0.000
C95 Leukaemia of unspecified cell type	0.695	0.305	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.694	0.306	0.000
C88 Malignant immunoproliferative diseases	0.694	0.306	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.694	0.306	0.000
M50 Cervical disk disorders	0.694	0.306	0.000
M12 Other specific arthropathies	0.694	0.306	0.000
Q00-Q07 Congenital malformations of the nervous system	0.693	0.307	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.693	0.307	0.000
I77.5 Necrosis of artery	0.692	0.308	0.000
I77.4 Coeliac artery compression syndrome	0.692	0.308	0.000
I77.3 Arterial fibromuscular dysplasia	0.692	0.308	0.000
Q44.5 Other congenital malformations of bile ducts	0.691	0.309	0.000
D09 Carcinoma in situ of other and unspecified sites	0.691	0.309	0.000
Q80-Q89 Other congenital malformations	0.690	0.310	0.000
I72.1 Aneurysm of artery of upper extremity	0.686	0.314	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.685	0.315	0.000
C02.1 Border of tongue	0.685	0.315	0.000
C91.9 Lymphoid leukaemia, unspecified	0.684	0.316	0.000
Q64 Other congenital malformations of urinary system	0.684	0.316	0.000
J99 Respiratory disorders in diseases classified elsewhere	0.684	0.316	0.000
M79 Other soft tissue disorders, not elsewhere classified	0.684	0.316	0.000
Q35-Q37 Cleft lip and cleft palate	0.682	0.317	0.000
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites	0.682	0.318	0.000
M10.97 Gout, unspecified (Ankle and foot)	0.682	0.318	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.681	0.319	0.000
Q39.9 Congenital malformation of oesophagus, unspecified	0.680	0.320	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.680	0.320	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.679	0.321	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.679	0.321	0.000
I72.9 Aneurysm of unspecified site	0.678	0.322	0.000
D01 Carcinoma in situ of other and unspecified digestive organs	0.677	0.323	0.000
C38 Malignant neoplasm of heart, mediastinum and pleura	0.676	0.324	0.000
D07.4 Penis	0.675	0.324	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.675	0.325	0.000
C94 Other leukaemias of specified cell type	0.675	0.325	0.000
E10.5 With peripheral circulatory complications	0.674	0.326	0.000
M08 Juvenile arthritis	0.674	0.326	0.000
M79.8 Other specified soft tissue disorders	0.674	0.326	0.000
M10.93 Gout, unspecified (Forearm)	0.672	0.328	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.672	0.328	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.672	0.328	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.672	0.328	0.000
D51.2 Transcobalamin II deficiency	0.671	0.329	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.671	0.329	0.000
D83 Common variable immunodeficiency	0.671	0.329	0.000
C02.3 Anterior two-thirds of tongue, part unspecified	0.670	0.329	0.000
C11 Malignant neoplasm of nasopharynx	0.670	0.330	0.000
C83.7 Burkitt's tumour	0.669	0.331	0.000
M72.5 Fasciitis, not elsewhere classified	0.668	0.331	0.000
D53.9 Nutritional anaemia, unspecified	0.668	0.332	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.667	0.333	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.667	0.333	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.667	0.333	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.667	0.333	0.000
E03.8 Other specified hypothyroidism	0.666	0.334	0.000
J45.8 Mixed asthma	0.666	0.334	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.665	0.335	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.665	0.335	0.000
I78 Diseases of capillaries	0.664	0.336	0.000
Q44.7 Other congenital malformations of liver	0.664	0.336	0.000
C85.0 Lymphosarcoma	0.663	0.337	0.000
D80 Immunodeficiency with predominantly antibody defects	0.662	0.338	0.000
C15.8 Overlapping lesion of oesophagus	0.662	0.338	0.000
C15.2 Abdominal part of oesophagus	0.662	0.338	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.661	0.339	0.000
M06.8 Other specified rheumatoid arthritis	0.660	0.339	0.000
M06.2 Rheumatoid bursitis	0.660	0.339	0.000
M06.1 Adult-onset Still's disease	0.660	0.339	0.000
C91.5 Adult T-cell leukaemia	0.660	0.340	0.000
C03 Malignant neoplasm of gum	0.658	0.342	0.000
Q43.8 Other specified congenital malformations of intestine	0.658	0.342	0.000
Q54.1 Hypospadias, penile	0.658	0.342	0.000
C31 Malignant neoplasm of accessory sinuses	0.658	0.342	0.000
C84.0 Mycosis fungoides	0.658	0.342	0.000
E50-E64 Other nutritional deficiencies	0.657	0.343	0.000
C92 Myeloid leukaemia	0.657	0.343	0.000
E10.6 With other specified complications	0.657	0.343	0.000
J41 Simple and mucopurulent chronic bronchitis	0.653	0.347	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.652	0.348	0.001
D50.8 Other iron deficiency anaemias	0.652	0.348	0.000
C22.1 Intrahepatic bile duct carcinoma	0.652	0.348	0.000
C00 Malignant neoplasm of lip	0.651	0.349	0.000
C45 Mesothelioma	0.651	0.349	0.000
M79.84 Other specified soft tissue disorders (Hand)	0.651	0.349	0.000
C84.4 Peripheral T-cell lymphoma	0.650	0.350	0.000
M10.4 Other secondary gout	0.649	0.351	0.000
M10.3 Gout due to impairment of renal function	0.649	0.351	0.000
M10.2 Drug-induced gout	0.649	0.351	0.000
M10.1 Lead-induced gout	0.649	0.351	0.000
M06.4 Inflammatory polyarthropathy	0.648	0.352	0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.648	0.352	0.000
C05 Malignant neoplasm of palate	0.647	0.353	0.000
I72.8 Aneurysm of other specified arteries	0.645	0.355	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.645	0.355	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.645	0.355	0.000
M71 Other bursopathies	0.643	0.357	0.000
E14.6 With other specified complications	0.640	0.359	0.000
E14.5 With peripheral circulatory complications	0.639	0.360	0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)	0.639	0.361	0.000
Q52 Other congenital malformations of female genitalia	0.638	0.362	0.000
J84 Other interstitial pulmonary diseases	0.637	0.363	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.637	0.363	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.636	0.364	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.635	0.365	0.000
M10.98 Gout, unspecified (Other)	0.634	0.366	0.000
M10.95 Gout, unspecified (Pelvic region and thigh)	0.634	0.366	0.000
M10.91 Gout, unspecified (Shoulder region)	0.634	0.366	0.000
M50.1 Cervical disk disorder with radiculopathy	0.633	0.367	0.000
D02 Carcinoma in situ of middle ear and respiratory system	0.633	0.367	0.000
I77.2 Rupture of artery	0.633	0.367	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.633	0.367	0.000
Q39.6 Diverticulum of oesophagus	0.632	0.368	0.000
E06.5 Other chronic thyroiditis	0.631	0.369	0.000
J95 Postprocedural respiratory disorders, not elsewhere classified	0.631	0.369	0.000
M73 Soft tissue disorders in diseases classified elsewhere	0.630	0.370	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.629	0.371	0.000
M72.9 Fibroblastic disorder, unspecified	0.628	0.372	0.000
M72.8 Other fibroblastic disorders	0.628	0.372	0.000
M72.6 Necrotizing fasciitis	0.628	0.372	0.000
M72.4 Pseudosarcomatous fibromatosis	0.628	0.372	0.000
M72.3 Nodular fasciitis	0.628	0.372	0.000
M72.08 Palmar fascial fibromatosis [Dupuytren]-Other	0.628	0.372	0.000
M72.07 Palmar fascial fibromatosis [Dupuytren]-Ankle/Foot	0.628	0.372	0.000
M72.06 Palmar fascial fibromatosis [Dupuytren]-Lower Leg	0.628	0.372	0.000
M72.05 Palmar fascial fibromatosis [Dupuytren]-Pelvic/Thigh	0.628	0.372	0.000
M72.03 Palmar fascial fibromatosis [Dupuytren]-Forearm	0.628	0.372	0.000
M72.02 Palmar fascial fibromatosis [Dupuytren]-Upper arm	0.628	0.372	0.000
M72.01 Palmar fascial fibromatosis [Dupuytren]-Shldr region	0.628	0.372	0.000
M72.00 Palmar fascial fibromatosis [Dupuytren]-Mult sites	0.628	0.372	0.000
J43.1 Panlobular emphysema	0.627	0.373	0.000
J43.0 MacLeod's syndrome	0.627	0.373	0.000
J45.1 Nonallergic asthma	0.626	0.374	0.000
C22.7 Other specified carcinomas of liver	0.626	0.374	0.000
C22.4 Other sarcomas of liver	0.626	0.374	0.000
C22.3 Angiosarcoma of liver	0.626	0.374	0.000
C22.2 Hepatoblastoma	0.626	0.374	0.000
D04 Carcinoma in situ of skin	0.625	0.375	0.000
I79.1 Aortitis in diseases classified elsewhere	0.621	0.378	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.621	0.378	0.000
C13.0 Postcricoid region	0.621	0.379	0.000
I12 Hypertensive renal disease	0.620	0.380	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.620	0.380	0.000
C41.0 Bones of skull and face	0.619	0.381	0.000
C93 Monocytic leukaemia	0.618	0.382	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.617	0.383	0.000
E46 Unspecified protein-energy malnutrition	0.617	0.383	0.000
M72.2 Plantar fascial fibromatosis	0.616	0.384	0.000
M60-M63 Disorders of muscles	0.616	0.384	0.000
C21.0 Anus, unspecified	0.616	0.384	0.000
D52 Folate deficiency anaemia	0.616	0.384	0.000
C84.9 Mature T/NK-cell lymphoma, unspecified	0.615	0.385	0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.615	0.385	0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.615	0.385	0.000
C84.3 Lymphoepithelioid lymphoma	0.615	0.385	0.000
C84.2 T-zone lymphoma	0.615	0.385	0.000
C84.1 Sezary's diease	0.615	0.385	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.614	0.385	0.000
M05.2 Rheumatoid vasculitis	0.614	0.385	0.000
M05.0 Felty's syndrome	0.614	0.385	0.000
J43.2 Centrilobular emphysema	0.613	0.387	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.612	0.388	0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.612	0.388	0.000
C91.8 Mature B-cell leukaemia Burkitt-type	0.611	0.389	0.000
C91.7 Other lymphoid leukaemia	0.611	0.389	0.000
C91.6 Prolymphocytic leukaemia of T-cell type	0.611	0.389	0.000
C91.3 Prolymphocytic leukaemia	0.611	0.389	0.000
C91.2 Subacute lymphocytic leukaemia	0.611	0.389	0.000
I00-I02 Acute rheumatic fever	0.611	0.389	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.610	0.390	0.000
M05.1 Rheumatoid lung disease	0.609	0.391	0.000
D03 Melanoma in situ	0.609	0.391	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.000	0.392	0.607
Q44.4 Choledochal cyst	0.607	0.393	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.607	0.393	0.000
Q44.2 Atresia of bile ducts	0.607	0.393	0.000
Q44.1 Other congenital malformations of gallbladder	0.607	0.393	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.607	0.393	0.000
J43.8 Other emphysema	0.607	0.393	0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.605	0.395	0.000
Q31 Congenital malformations of larynx	0.605	0.395	0.000
Q40 Other congenital malformations of upper alimentary tract	0.604	0.396	0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.604	0.396	0.000
C33 Malignant neoplasm of trachea	0.604	0.396	0.000
C16.8 Overlapping lesion of stomach	0.603	0.397	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.603	0.397	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.603	0.397	0.000
E13 Other specified diabetes mellitus	0.601	0.399	0.000
G36 Other acute disseminated demyelination	0.001	0.399	0.601
J99.1 Respiratory disorders in other diffuse connective tissue disorders	0.601	0.399	0.000
I73.8 Other specified peripheral vascular diseases	0.601	0.399	0.000
C91.4 Hairy-cell leukaemia	0.601	0.399	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.598	0.402	0.000
C16.9 Stomach, unspecified	0.597	0.403	0.000
Q43.1 Hirschsprung's disease	0.597	0.403	0.000
D63.1 Anaemia in other chronic diseases classified elsewhere	0.596	0.404	0.000
M76 Enthesopathies of lower limb, excluding foot	0.596	0.404	0.000
C91.0 Acute lymphoblastic leukaemia	0.596	0.404	0.000
I15 Secondary hypertension	0.596	0.404	0.000
M53 Other dorsopathies, not elsewhere classified	0.596	0.404	0.000
J95.0 Tracheostomy malfunction	0.594	0.406	0.000
J99.8 Respiratory disorders in other diseases classified elsewhere	0.594	0.406	0.000
E06.4 Drug-induced thyroiditis	0.591	0.409	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.591	0.409	0.000
E06.0 Acute thyroiditis	0.591	0.409	0.000
M72.1 Knuckle pads	0.591	0.409	0.000
M00-M03 Infectious arthropathies	0.591	0.409	0.000
Q43.3 Congenital malformations of intestinal fixation	0.590	0.409	0.000
M40-M43 Deforming dorsopathies	0.590	0.410	0.000
Q43.0 Meckel's diverticulum	0.589	0.411	0.000
I70.0 Atherosclerosis of aorta	0.589	0.411	0.000
E06.1 Subacute thyroiditis	0.588	0.412	0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.587	0.413	0.000
I72.3 Aneurysm of iliac artery	0.586	0.414	0.000
Q85 Phakomatoses, not elsewhere classified	0.584	0.416	0.000
C02.8 Overlapping lesion of tongue	0.584	0.416	0.000
C02.0 Dorsal surface of tongue	0.584	0.416	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.584	0.416	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.583	0.417	0.000
D06 Carcinoma in situ of cervix uteri	0.583	0.417	0.000
M10.00 Idiopathic gout (Multiple sites)	0.583	0.417	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.582	0.417	0.000
Q43.7 Persistent cloaca	0.582	0.418	0.000
Q43.6 Congenital fistula of rectum and anus	0.582	0.418	0.000
Q43.5 Ectopic anus	0.582	0.418	0.000
Q43.4 Duplication of intestine	0.582	0.418	0.000
Q43.2 Other congenital functional disorders of colon	0.582	0.418	0.000
C45.9 Mesothelioma, unspecified	0.582	0.418	0.000
Q38.1 Ankyloglossia	0.581	0.419	0.000
C16.2 Body of stomach	0.580	0.420	0.000
E11.6 With other specified complications	0.580	0.420	0.000
C83.1 Small cleaved cell (diffuse)	0.579	0.421	0.000
I78.9 Disease of capillaries, unspecified	0.578	0.422	0.000
C40 Malignant neoplasm of bone and articular cartilage of limbs	0.578	0.422	0.000
C32.8 Overlapping lesion of larynx	0.578	0.422	0.000
C32.3 Laryngeal cartilage	0.578	0.422	0.000
C32.2 Subglottis	0.578	0.422	0.000
D09.0 Bladder	0.578	0.422	0.000
D83.9 Common variable immunodeficiency, unspecified	0.578	0.422	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.577	0.423	0.000
C83.6 Undifferentiated (diffuse)	0.577	0.423	0.000
C83.5 Lymphoblastic (diffuse)	0.577	0.423	0.000
C83.4 Immunoblastic (diffuse)	0.577	0.423	0.000
C83.2 Mixed small and large cell (diffuse)	0.577	0.423	0.000
Q51 Congenital malformations of uterus and cervix	0.576	0.424	0.000
Q60.6 Potter's syndrome	0.575	0.425	0.000
Q60.5 Renal hypoplasia, unspecified	0.575	0.425	0.000
Q60.4 Renal hypoplasia, bilateral	0.575	0.425	0.000
Q60.3 Renal hypoplasia, unilateral	0.575	0.425	0.000
Q60.1 Renal agenesis, bilateral	0.575	0.425	0.000
M51.37 Other intervertebral disc degeneration, lumbosacral region	0.575	0.425	0.000
Q55 Other congenital malformations of male genital organs	0.575	0.425	0.000
D63.0 Anaemia in neoplastic disease	0.574	0.426	0.000
D81 Combined immunodeficiencies	0.574	0.426	0.000
D53.8 Other specified nutritional anaemias	0.574	0.426	0.000
D53.2 Scorbutic anaemia	0.574	0.426	0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.574	0.426	0.000
D53.0 Protein deficiency anaemia	0.574	0.426	0.000
C16.6 Greater curvature of stomach, unspecified	0.573	0.427	0.000
Q39.8 Other congenital malformations of oesophagus	0.572	0.427	0.000
Q39.5 Congenital dilatation of oesophagus	0.572	0.427	0.000
Q39.3 Congenital stenosis and stricture of oesophagus	0.572	0.427	0.000
Q39.2 Congenital tracheooesophageal fistula without atresia	0.572	0.427	0.000
Q39.1 Atresia of oesophagus with tracheooesophageal fistula	0.572	0.427	0.000
Q39.0 Atresia of oesophagus without fistula	0.572	0.427	0.000
I72.2 Aneurysm of renal artery	0.571	0.428	0.000
E53 Deficiency of other B group vitamins	0.572	0.428	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.571	0.429	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.570	0.430	0.000
C42 hematopoietic and reticuloendothelial systems (ICD-O-3 specific)	0.569	0.431	0.000
C86.5 Angioimmunoblastic T-cell lymphoma	0.569	0.431	0.000
E07.8 Other specified disorders of thyroid	0.569	0.431	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.568	0.432	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.568	0.432	0.000
C81.9 Hodgkin's disease, unspecified	0.568	0.432	0.000
G37.5 Concentric sclerosis [Balo]	0.000	0.432	0.567
G37.4 Subacute necrotising myelitis	0.000	0.432	0.567
G37.2 Central pontine myelinolysis	0.000	0.432	0.567
G37.1 Central demyelination of corpus callosum	0.000	0.432	0.567
G37.0 Diffuse sclerosis	0.000	0.432	0.567
M79.82 Other specified soft tissue disorders (Upper arm)	0.566	0.434	0.000
M10.07 Idiopathic gout (Ankle and foot)	0.566	0.434	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.565	0.435	0.000
C45.0 Mesothelioma of pleura	0.565	0.435	0.000
I12.9 Hypertensive renal disease without renal failure	0.564	0.436	0.000
M79.89 Other specified soft tissue disorders (Site unspecified)	0.563	0.437	0.000
J42 Unspecified chronic bronchitis	0.563	0.437	0.000
D03.5 Melanoma in situ of trunk	0.561	0.439	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations