TreeWAS – Variant ID: rs71536865

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M54 Dorsalgia	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
M50-M54 Other dorsopathies	1.000	0.000	0.000
M80-M85 Disorders of bone density and structure	1.000	0.000	0.000
M81 Osteoporosis without pathological fracture	0.999	0.001	0.000
# Top node	0.999	0.001	0.000
M81.9 Osteoporosis, unspecified	0.998	0.002	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.996	0.004	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.996	0.004	0.000
Chapter XI Diseases of the digestive system	0.996	0.004	0.000
K50-K52 Noninfective enteritis and colitis	0.991	0.009	0.000
M54.5 Low back pain	0.989	0.011	0.000
L20-L30 Dermatitis and eczema	0.985	0.015	0.000
M54.56 Low back pain (Lumbar region)	0.982	0.018	0.000
K70-K77 Diseases of liver	0.979	0.021	0.000
M54.9 Dorsalgia, unspecified	0.976	0.024	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.968	0.032	0.000
M54.2 Cervicalgia	0.968	0.032	0.000
K35-K38 Diseases of appendix	0.967	0.033	0.000
L80-L99 Other disorders of the skin and subcutaneous tissue	0.964	0.036	0.000
K50 Crohn's disease [regional enteritis]	0.960	0.040	0.000
M54.22 Cervicalgia (Cervical region)	0.955	0.045	0.000
K74 Fibrosis and cirrhosis of liver	0.954	0.046	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.953	0.047	0.000
K52 Other non-infective gastro-enteritis and colitis	0.951	0.049	0.000
L29 Pruritus	0.947	0.053	0.000
K35 Acute appendicitis	0.947	0.053	0.000
M54.99 Dorsalgia, unspecified (Site unspecified)	0.944	0.056	0.000
M54.3 Sciatica	0.943	0.057	0.000
M85 Other disorders of bone density and structure	0.943	0.057	0.000
M81.98 Osteoporosis, unspecified (Other)	0.941	0.059	0.000
S60-S69 Injuries to the wrist and hand	0.935	0.065	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.928	0.072	0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified	0.926	0.074	0.000
Chapter XX External causes of morbidity and mortality	0.922	0.078	0.000
K74.0 Hepatic fibrosis	0.912	0.088	0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.908	0.092	0.000
K35.0 Acute appendicitis with generalised peritonitis	0.908	0.092	0.000
L28 Lichen simplex chronicus and prurigo	0.906	0.094	0.000
L29.9 Pruritus, unspecified	0.901	0.099	0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.000	0.100	0.900
M80 Osteoporosis with pathological fracture	0.897	0.103	0.000
T66-T78 Other and unspecified effects of external causes	0.890	0.110	0.000
S61 Open wound of wrist and hand	0.884	0.116	0.000
C77.3 Axillary and upper limb lymph nodes	0.000	0.116	0.884
Chapter V Mental and behavioural disorders	0.883	0.117	0.000
M54.57 Low back pain (Lumbosacral region)	0.883	0.117	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.882	0.118	0.000
X60-X84 Intentional self-harm	0.879	0.121	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.000	0.124	0.876
M45-M49 Spondylopathies	0.874	0.126	0.000
L85 Other epidermal thickening	0.874	0.126	0.000
C79 Secondary malignant neoplasm of other sites	0.000	0.127	0.873
S60 Superficial injury of wrist and hand	0.869	0.131	0.000
K35.9 Acute appendicitis, unspecified	0.868	0.132	0.000
L93 Lupus erythematosus	0.867	0.133	0.000
S10-S19 Injuries to the neck	0.867	0.133	0.000
C77.0 Lymph nodes of head, face and neck	0.000	0.139	0.861
K75 Other inflammatory liver diseases	0.859	0.141	0.000
L90 Atrophic disorders of skin	0.858	0.142	0.000
S61.1 Open wound of finger(s) with damage to nail	0.855	0.145	0.000
Q80-Q89 Other congenital malformations	0.843	0.157	0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.842	0.158	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.841	0.159	0.000
M53 Other dorsopathies, not elsewhere classified	0.839	0.161	0.000
L50-L54 Urticaria and erythema	0.838	0.162	0.000
M54.39 Sciatica (Site unspecified)	0.836	0.164	0.000
S90-S99 Injuries to the ankle and foot	0.835	0.165	0.000
L98.0 Pyogenic granuloma	0.834	0.166	0.000
L90.0 Lichen sclerosus et atrophicus	0.834	0.166	0.000
C79.2 Secondary malignant neoplasm of skin	0.000	0.169	0.831
M85.8 Other specified disorders of bone density and structure	0.829	0.171	0.000
L98.8 Other specified disorders of skin and subcutaneous tissue	0.828	0.172	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.824	0.176	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.822	0.178	0.000
K50.0 Crohn's disease of small intestine	0.821	0.179	0.000
C77.2 Intra-abdominal lymph nodes	0.000	0.181	0.819
K50.8 Other Crohn's disease	0.818	0.182	0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.000	0.184	0.816
K50.1 Crohn's disease of large intestine	0.814	0.186	0.000
C79.8 Secondary malignant neoplasm of other specified sites	0.000	0.187	0.813
T20-T25 Burns and corrosions of external body surface, specified by site	0.813	0.187	0.000
L29.2 Pruritus vulvae	0.809	0.191	0.000
L85.9 Epidermal thickening, unspecified	0.806	0.194	0.000
K50.9 Crohn's disease, unspecified	0.803	0.197	0.000
L10-L14 Bullous disorders	0.802	0.198	0.000
M54.36 Sciatica (Lumbar region)	0.801	0.199	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.798	0.202	0.000
L93.0 Discoid lupus erythematosus	0.798	0.202	0.000
F30-F39 Mood [affective] disorders	0.798	0.202	0.000
K51 Ulcerative colitis	0.797	0.203	0.000
L28.0 Lichen simplex chronicus	0.796	0.204	0.000
L30 Other dermatitis	0.795	0.205	0.000
K74.6 Other and unspecified cirrhosis of liver	0.795	0.205	0.000
T78 Adverse effects, not elsewhere classified	0.794	0.206	0.000
C79.7 Secondary malignant neoplasm of adrenal gland	0.000	0.209	0.791
C77.9 Lymph node, unspecified	0.000	0.210	0.790
M54.4 Lumbago with sciatica	0.787	0.213	0.000
S60.9 Superficial injury of wrist and hand, unspecified	0.786	0.214	0.000
M45 Ankylosing spondylitis	0.783	0.217	0.000
M54.50 Low back pain (Multiple sites in spine)	0.782	0.218	0.000
K38 Other diseases of appendix	0.782	0.218	0.000
D60-D64 Aplastic and other anaemias	0.782	0.218	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.780	0.220	0.000
K75.9 Inflammatory liver disease, unspecified	0.778	0.222	0.000
C77.4 Inguinal and lower limb lymph nodes	0.000	0.223	0.777
L28.1 Prurigo nodularis	0.774	0.226	0.000
Q50-Q56 Congenital malformations of genital organs	0.774	0.226	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.773	0.227	0.000
Q00-Q07 Congenital malformations of the nervous system	0.771	0.229	0.000
K65-K67 Diseases of peritoneum	0.769	0.231	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.768	0.232	0.000
M54.37 Sciatica (Lumbosacral region)	0.768	0.232	0.000
Q82 Other congenital malformations of skin	0.767	0.233	0.000
L94 Other localised connective tissue disorders	0.766	0.234	0.000
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics	0.766	0.234	0.000
L29.8 Other pruritus	0.764	0.236	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.762	0.238	0.000
L98.4 Chronic ulcer of skin, not elsewhere classified	0.761	0.239	0.000
L02 Cutaneous abscess, furuncle and carbuncle	0.761	0.239	0.000
M85.6 Other cyst of bone	0.760	0.240	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.760	0.240	0.000
K74.3 Primary biliary cirrhosis	0.760	0.240	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.757	0.243	0.000
M81.2 Osteoporosis of disuse	0.756	0.244	0.000
M85.0 Fibrous dysplasia (monostotic)	0.755	0.245	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.754	0.246	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.754	0.246	0.000
Chapter VIII Diseases of the ear and mastoid process	0.753	0.247	0.000
L80 Vitiligo	0.753	0.247	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.753	0.247	0.000
K75.8 Other specified inflammatory liver diseases	0.749	0.251	0.000
F45 Somatoform disorders	0.748	0.252	0.000
L23 Allergic contact dermatitis	0.747	0.253	0.000
M00-M03 Infectious arthropathies	0.746	0.254	0.000
F80-F89 Disorders of psychological development	0.745	0.255	0.000
F32 Depressive episode	0.745	0.255	0.000
S60.2 Contusion of other parts of wrist and hand	0.744	0.256	0.000
T66 Unspecified effects of radiation	0.744	0.256	0.000
M54.96 Dorsalgia, unspecified (Lumbar region)	0.744	0.256	0.000
D55-D59 Haemolytic anaemias	0.743	0.257	0.000
M85.9 Disorder of bone density and structure, unspecified	0.742	0.258	0.000
D80-D89 Certain disorders involving the immune mechanism	0.742	0.258	0.000
L50 Urticaria	0.740	0.260	0.000
D69 Purpura and other haemorrhagic conditions	0.738	0.262	0.000
K36 Other appendicitis	0.737	0.263	0.000
M54.55 Low back pain (Thoracolumbar region)	0.737	0.263	0.000
M60-M63 Disorders of muscles	0.736	0.264	0.000
M82 Osteoporosis in diseases classified elsewhere	0.735	0.265	0.000
K35.3 Acute appendicitis with localized peritonitis	0.735	0.265	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.734	0.266	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.733	0.267	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.731	0.269	0.000
K51.9 Ulcerative colitis, unspecified	0.730	0.270	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.727	0.273	0.000
M54.6 Pain in thoracic spine	0.726	0.274	0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system	0.724	0.275	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.724	0.276	0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified	0.723	0.277	0.000
M80.8 Other osteoporosis with pathological fracture	0.723	0.277	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.722	0.278	0.000
X67 Intentional self-poisoning by and exposure to other gases and vapours	0.720	0.280	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.720	0.280	0.000
S50-S59 Injuries to the elbow and forearm	0.719	0.281	0.000
C80 Malignant neoplasm without specification of site	0.000	0.282	0.718
K72 Hepatic failure, not elsewhere classified	0.717	0.283	0.000
Chapter VI Diseases of the nervous system	0.717	0.283	0.000
L82 Seborrhoeic keratosis	0.717	0.283	0.000
M54.8 Other dorsalgia	0.717	0.283	0.000
M54.0 Panniculitis affecting regions of neck and back	0.717	0.283	0.000
M83 Adult osteomalacia	0.717	0.283	0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.717	0.283	0.000
D62 Acute posthaemorrhagic anaemia	0.717	0.283	0.000
F32.1 Moderate depressive episode	0.717	0.283	0.000
M81.8 Other osteoporosis	0.716	0.284	0.000
M81.6 Localised osteoporosis [Lequesne]	0.716	0.284	0.000
M81.5 Idiopathic osteoporosis	0.716	0.284	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.716	0.284	0.000
M81.1 Postoophorectomy osteoporosis	0.716	0.284	0.000
M81.0 Postmenopausal osteoporosis	0.716	0.284	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.716	0.284	0.000
S61.8 Open wound of other parts of wrist and hand	0.716	0.284	0.000
L20 Atopic dermatitis	0.716	0.284	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.716	0.284	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.716	0.284	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.716	0.284	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.716	0.284	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.716	0.284	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.716	0.284	0.000
X50-X57 Overexertion, travel and privation	0.715	0.285	0.000
X20-X29 Contact with venomous animals and plants	0.714	0.286	0.000
M91-M94 Chondropathies	0.714	0.286	0.000
X10-X19 Contact with heat and hot substances	0.712	0.287	0.000
M54.54 Low back pain-Thoracic	0.709	0.290	0.000
M54.53 Low back pain-Cervicothoracic	0.709	0.290	0.000
M54.52 Low back pain-Cervical	0.709	0.290	0.000
M54.51 Low back pain-Occipit-atl-axl	0.709	0.290	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.708	0.291	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.707	0.293	0.000
L25 Unspecified contact dermatitis	0.706	0.294	0.000
L24 Irritant contact dermatitis	0.706	0.294	0.000
L21 Seborrhoeic dermatitis	0.706	0.294	0.000
L26 Exfoliative dermatitis	0.706	0.294	0.000
L22 Diaper [napkin] dermatitis	0.706	0.294	0.000
S67 Crushing injury of wrist and hand	0.706	0.294	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.704	0.295	0.000
W50-W64 Exposure to animate mechanical forces	0.704	0.296	0.000
Y00-Y09 Assault	0.704	0.296	0.000
D61 Other aplastic anaemias	0.703	0.297	0.000
T78.2 Anaphylactic shock, unspecified	0.702	0.298	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.702	0.298	0.000
M48 Other spondylopathies	0.702	0.298	0.000
K77 Liver disorders in diseases classified elsewhere	0.702	0.298	0.000
K71 Toxic liver disease	0.702	0.298	0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)	0.700	0.300	0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)	0.700	0.300	0.000
M54.92 Dorsalgia, unspecified (Cervical region)	0.700	0.300	0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)	0.700	0.300	0.000
K52.3 Indeterminate colitis	0.699	0.301	0.000
M46 Other inflammatory spondylopathies	0.698	0.302	0.000
K76 Other diseases of liver	0.697	0.303	0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.697	0.303	0.000
K52.0 Gastro-enteritis and colitis due to radiation	0.695	0.305	0.000
V01-V09 Pedestrian injured in transport accident	0.695	0.305	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.694	0.305	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.694	0.306	0.000
T33-T35 Frostbite	0.694	0.306	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.694	0.306	0.000
M54.28 Cervicalgia-Sacral/sacrococ	0.694	0.306	0.000
M54.27 Cervicalgia-Lumbosacral	0.694	0.306	0.000
M54.26 Cervicalgia-Lumbar	0.694	0.306	0.000
M54.25 Cervicalgia-Thoracolumbar	0.694	0.306	0.000
M54.24 Cervicalgia-Thoracic	0.694	0.306	0.000
M54.23 Cervicalgia (Cervicothoracic region)	0.694	0.306	0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)	0.694	0.306	0.000
M54.20 Cervicalgia-Mult site	0.694	0.306	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.692	0.308	0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.691	0.309	0.000
L87 Transepidermal elimination disorders	0.691	0.309	0.000
L88 Pyoderma gangrenosum	0.691	0.309	0.000
L86 Keratoderma in diseases classified elsewhere	0.691	0.309	0.000
M86-M90 Other osteopathies	0.691	0.309	0.000
M50 Cervical disk disorders	0.691	0.309	0.000
K74.5 Biliary cirrhosis, unspecified	0.690	0.309	0.000
Q82.8 Other specified congenital malformations of skin	0.690	0.310	0.000
K70 Alcoholic liver disease	0.690	0.310	0.000
L81 Other disorders of pigmentation	0.690	0.310	0.000
S61.9 Open wound of wrist and hand, part unspecified	0.690	0.310	0.000
V98-V99 Other and unspecified transport accidents	0.690	0.310	0.000
F44 Dissociative [conversion] disorders	0.690	0.310	0.000
H90-H95 Other disorders of ear	0.688	0.312	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.688	0.312	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.687	0.313	0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.687	0.313	0.000
X60.8 Other specified place	0.685	0.315	0.000
S19 Other and unspecified injuries of neck	0.685	0.315	0.000
K74.4 Secondary biliary cirrhosis	0.684	0.316	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.684	0.316	0.000
K74.1 Hepatic sclerosis	0.684	0.316	0.000
M51 Other intervertebral disk disorders	0.684	0.316	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.683	0.317	0.000
Q35-Q37 Cleft lip and cleft palate	0.683	0.317	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.683	0.317	0.000
S65 Injury of blood vessels at wrist and hand level	0.682	0.318	0.000
W20-W49 Exposure to inanimate mechanical forces	0.682	0.318	0.000
D69.6 Thrombocytopenia, unspecified	0.682	0.318	0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.682	0.318	0.000
M40-M43 Deforming dorsopathies	0.682	0.318	0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.682	0.318	0.000
S70-S79 Injuries to the hip and thigh	0.681	0.319	0.000
Q27 Other congenital malformations of peripheral vascular system	0.679	0.321	0.000
M81.4 Drug-induced osteoporosis	0.679	0.321	0.000
L29.3 Anogenital pruritus, unspecified	0.679	0.321	0.000
L29.1 Pruritus scroti	0.679	0.321	0.000
L89 Decubitus ulcer	0.678	0.322	0.000
C79.6 Secondary malignant neoplasm of ovary	0.000	0.323	0.677
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.677	0.323	0.000
K52.8 Other specified non-infective gastro-enteritis and colitis	0.677	0.323	0.000
V80-V89 Other land transport accidents	0.677	0.323	0.000
T00-T07 Injuries involving multiple body regions	0.676	0.323	0.000
M54.35 Sciatica (Thoracolumbar region)	0.676	0.324	0.000
M54.34 Sciatica-Thoracic	0.676	0.324	0.000
M54.33 Sciatica-Cervicothoracic	0.676	0.324	0.000
M54.32 Sciatica-Cervical	0.676	0.324	0.000
M54.31 Sciatica-Occipit-atl-axl	0.676	0.324	0.000
M54.30 Sciatica (Multiple sites in spine)	0.676	0.324	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.676	0.324	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.676	0.324	0.000
M85.5 Aneurysmal bone cyst	0.676	0.324	0.000
M85.4 Solitary bone cyst	0.676	0.324	0.000
M85.3 Osteitis condensans	0.676	0.324	0.000
M85.2 Hyperostosis of skull	0.676	0.324	0.000
M85.1 Skeletal fluorosis	0.676	0.324	0.000
L50.9 Urticaria, unspecified	0.676	0.324	0.000
S92 Fracture of foot, except ankle	0.675	0.325	0.000
S13.4 Sprain and strain of cervical spine	0.673	0.327	0.000
M54.94 Dorsalgia, unspecified (Thoracic region)	0.672	0.328	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.671	0.329	0.000
Y40 Systemic antibiotics	0.671	0.329	0.000
H93 Other disorders of ear, not elsewhere classified	0.670	0.330	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.668	0.332	0.000
W00-W19 Falls	0.667	0.333	0.000
S10 Superficial injury of neck	0.667	0.333	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.667	0.333	0.000
V10-V19 Pedal cyclist injured in transport accident	0.667	0.333	0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck	0.666	0.334	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.666	0.334	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.666	0.334	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.666	0.334	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.666	0.334	0.000
K02 Dental caries	0.666	0.334	0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.666	0.334	0.000
C77.5 Intrapelvic lymph nodes	0.000	0.336	0.664
Q25 Congenital malformations of great arteries	0.664	0.336	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.663	0.337	0.000
K73 Chronic hepatitis, not elsewhere classified	0.663	0.337	0.000
Y35-Y36 Legal intervention and operations of war	0.661	0.339	0.000
Y10-Y34 Event of undetermined intent	0.661	0.339	0.000
X85-X99 Assault	0.661	0.339	0.000
X30-X39 Exposure to forces of nature	0.661	0.339	0.000
X00-X09 Exposure to smoke, fire and flames	0.661	0.339	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.661	0.339	0.000
W75-W84 Other accidental threats to breathing	0.661	0.339	0.000
W65-W74 Accidental drowning and submersion	0.661	0.339	0.000
V95-V97 Air and space transport accidents	0.661	0.339	0.000
V90-V94 Water transport accidents	0.661	0.339	0.000
V70-V79 Bus occupant injured in transport accident	0.661	0.339	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.661	0.339	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.661	0.339	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.661	0.339	0.000
M84 Disorders of continuity of bone	0.660	0.340	0.000
M54.46 Lumbago with sciatica (Lumbar region)	0.659	0.341	0.000
F43 Reaction to severe stress, and adjustment disorders	0.659	0.341	0.000
H93.1 Tinnitus	0.658	0.342	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.657	0.343	0.000
Chapter X Diseases of the respiratory system	0.657	0.343	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.656	0.344	0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.656	0.344	0.000
C77.1 Intrathoracic lymph nodes	0.000	0.344	0.656
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.656	0.344	0.000
T46.1 Calcium-channel blockers	0.655	0.345	0.000
Y48 Anaesthetics and therapeutic gases	0.653	0.347	0.000
C77.8 Lymph nodes of multiple regions	0.000	0.347	0.653
T78.3 Angioneurotic oedema	0.651	0.349	0.000
L98.7 Excessive and redundant skin and subcutaneous tissue	0.651	0.349	0.000
L98.6 Other infiltrative disorders of skin and subcutaneous tissue	0.651	0.349	0.000
L98.5 Mucinosis of skin	0.651	0.349	0.000
L98.3 Eosinophilic cellulitis [Wells]	0.651	0.349	0.000
L98.2 Febrile neutrophilic dermatosis [Sweet]	0.651	0.349	0.000
L98.1 Factitial dermatitis	0.651	0.349	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.651	0.349	0.000
T36 Poisoning by systemic antibiotics	0.651	0.349	0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.000	0.350	0.650
L28.2 Other prurigo	0.650	0.350	0.000
Q53 Undescended testicle	0.649	0.351	0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.648	0.352	0.000
K02.9 Dental caries, unspecified	0.648	0.352	0.000
F48 Other neurotic disorders	0.648	0.352	0.000
K35.8 Acute appendicitis, other and unspecified	0.648	0.352	0.000
F34 Persistent mood [affective] disorders	0.646	0.354	0.000
K38.9 Disease of appendix, unspecified	0.643	0.357	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.643	0.357	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.643	0.357	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.643	0.357	0.000
F81 Specific developmental disorders of scholastic skills	0.642	0.358	0.000
Q23 Congenital malformations of aortic and mitral valves	0.642	0.358	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.642	0.358	0.000
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s	0.641	0.359	0.000
K38.1 Appendicular concretions	0.641	0.359	0.000
Q05 Spina bifida	0.640	0.359	0.000
M54.1 Radiculopathy	0.640	0.360	0.000
L30.8 Other specified dermatitis	0.639	0.361	0.000
T75 Effects of other external causes	0.638	0.362	0.000
T74 Maltreatment syndromes	0.638	0.362	0.000
T73 Effects of other deprivation	0.638	0.362	0.000
T70 Effects of air pressure and water pressure	0.638	0.362	0.000
T69 Other effects of reduced temperature	0.638	0.362	0.000
T67 Effects of heat and light	0.638	0.362	0.000
T71 Asphyxiation	0.638	0.362	0.000
J00-J06 Acute upper respiratory infections	0.638	0.362	0.000
G90-G99 Other disorders of the nervous system	0.638	0.362	0.000
L85.8 Other specified epidermal thickening	0.637	0.363	0.000
G56 Mononeuropathies of upper limb	0.636	0.364	0.000
T23 Burn and corrosion of wrist and hand	0.636	0.364	0.000
T51 Toxic effect of alcohol	0.635	0.365	0.000
L51 Erythema multiforme	0.635	0.365	0.000
T40.2 Other opioids	0.634	0.366	0.000
F40 Phobic anxiety disorders	0.634	0.366	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.634	0.366	0.000
F45.8 Other somatoform disorders	0.634	0.366	0.000
T68 Hypothermia	0.633	0.367	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.633	0.367	0.000
F70-F79 Mental retardation	0.633	0.367	0.000
V20-V29 Motorcycle rider injured in transport accident	0.633	0.367	0.000
K35.2 Acute appendicitis with generalized peritonitis	0.633	0.367	0.000
K65 Peritonitis	0.632	0.368	0.000
L11 Other acantholytic disorders	0.632	0.368	0.000
Q85 Phakomatoses, not elsewhere classified	0.632	0.368	0.000
F33 Recurrent depressive disorder	0.631	0.369	0.000
T40.4 Other synthetic narcotics	0.631	0.369	0.000
S20-S29 Injuries to the thorax	0.631	0.369	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.630	0.369	0.000
T91 Sequelae of injuries of neck and trunk	0.630	0.370	0.000
X84 Intentional self-harm by unspecified means	0.630	0.370	0.000
X83 Intentional self-harm by other specified means	0.630	0.370	0.000
X82 Intentional self-harm by crashing of motor vehicle	0.630	0.370	0.000
X81 Intentional self-harm by jumping or lying before moving object	0.630	0.370	0.000
X80 Intentional self-harm by jumping from a high place	0.630	0.370	0.000
X79 Intentional self-harm by blunt object	0.630	0.370	0.000
X77 Intentional self-harm by steam, hot vapours and hot objects	0.630	0.370	0.000
X76 Intentional self-harm by smoke, fire and flames	0.630	0.370	0.000
X75 Intentional self-harm by explosive material	0.630	0.370	0.000
X74 Intentional self-harm by other and unspecified firearm discharge	0.630	0.370	0.000
X73 Intentional self-harm by rifle, shotgun and larger firearm discharge	0.630	0.370	0.000
X72 Intentional self-harm by handgun discharge	0.630	0.370	0.000
X71 Intentional self-harm by drowning and submersion	0.630	0.370	0.000
X70 Intentional self-harm by hanging, strangulation and suffocation	0.630	0.370	0.000
X69 Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances	0.630	0.370	0.000
X68 Intentional self-poisoning by and exposure to pesticides	0.630	0.370	0.000
X66 Intentional self-poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours	0.630	0.370	0.000
X65 Intentional self-poisoning by and exposure to alcohol	0.630	0.370	0.000
X64 Intentional self-poisoning by and exposure to other and unspecified drugs, medicaments and biological substances	0.630	0.370	0.000
X61 Intentional self-poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.630	0.370	0.000
L27 Dermatitis due to substances taken internally	0.630	0.370	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.629	0.371	0.000
Q24 Other congenital malformations of heart	0.629	0.371	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.628	0.372	0.000
M49 Spondylopathies in diseases classified elsewhere	0.627	0.373	0.000
L85.3 Xerosis cutis	0.626	0.374	0.000
L85.2 Keratosis punctata (palmaris et plantaris)	0.626	0.374	0.000
L85.1 Acquired keratosis [keratoderma] palmaris et plantaris	0.626	0.374	0.000
L85.0 Acquired ichthyosis	0.626	0.374	0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.000	0.374	0.626
F60-F69 Disorders of adult personality and behaviour	0.625	0.374	0.000
F45.0 Somatisation disorder	0.625	0.375	0.000
F41 Other anxiety disorders	0.624	0.376	0.000
K35.1 Acute appendicitis with peritoneal abscess	0.624	0.376	0.000
S60.7 Multiple superficial injuries of wrist and hand	0.623	0.377	0.000
S60.1 Contusion of finger(s) with damage to nail	0.623	0.377	0.000
S60.0 Contusion of finger(s) without damage to nail	0.623	0.377	0.000
J95-J99 Other diseases of the respiratory system	0.623	0.377	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.622	0.378	0.000
L93.2 Other local lupus erythematosus	0.622	0.378	0.000
L93.1 Subacute cutaneous lupus erythematosus	0.622	0.378	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.622	0.378	0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.622	0.378	0.000
S17 Crushing injury of neck	0.621	0.379	0.000
S15 Injury of blood vessels at neck level	0.621	0.379	0.000
S11 Open wound of neck	0.621	0.379	0.000
S18 Traumatic amputation at neck level	0.621	0.379	0.000
S16 Injury of muscle and tendon at neck level	0.621	0.379	0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.621	0.379	0.000
D59 Acquired haemolytic anaemia	0.621	0.379	0.000
M48.5 Collapsed vertebra, not elsewhere classified	0.621	0.379	0.000
S66.8 Injury of other muscles and tendons at wrist and hand level	0.620	0.380	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.620	0.380	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.620	0.380	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.620	0.380	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.619	0.381	0.000
L13 Other bullous disorders	0.618	0.382	0.000
X78 Intentional self-harm by sharp object	0.618	0.382	0.000
L94.9 Localised connective tissue disorder, unspecified	0.618	0.382	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.617	0.383	0.000
L95 Vasculitis limited to skin, not elsewhere classified	0.617	0.383	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.617	0.383	0.000
K75.2 Nonspecific reactive hepatitis	0.616	0.384	0.000
K75.1 Phlebitis of portal vein	0.616	0.384	0.000
L90.9 Atrophic disorder of skin, unspecified	0.615	0.384	0.000
L90.8 Other atrophic disorders of skin	0.615	0.384	0.000
L90.6 Striae atrophicae	0.615	0.384	0.000
L90.4 Acrodermatitis chronica atrophicans	0.615	0.384	0.000
L90.3 Atrophoderma of Pasini and Pierini	0.615	0.384	0.000
L90.2 Anetoderma of Jadassohn-Pellizzari	0.615	0.384	0.000
L90.1 Anetoderma of Schweninger-Buzzi	0.615	0.384	0.000
S69 Other and unspecified injuries of wrist and hand	0.615	0.385	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.615	0.385	0.000
L97 Ulcer of lower limb, not elsewhere classified	0.614	0.386	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.614	0.386	0.000
L81.9 Disorder of pigmentation, unspecified	0.614	0.386	0.000
V40-V49 Car occupant injured in transport accident	0.613	0.386	0.000
X63.0 Home	0.614	0.386	0.000
Q82.5 Congenital nonneoplastic naevus	0.613	0.387	0.000
D61.9 Aplastic anaemia, unspecified	0.612	0.388	0.000
S61.7 Multiple open wounds of wrist and hand	0.612	0.388	0.000
S12 Fracture of neck	0.612	0.388	0.000
D86 Sarcoidosis	0.610	0.390	0.000
J00 Acute nasopharyngitis [common cold]	0.610	0.390	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.609	0.391	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.608	0.392	0.000
K52.1 Toxic gastro-enteritis and colitis	0.607	0.393	0.000
X67.9 Unspecified place	0.607	0.393	0.000
Chapter I Certain infectious and parasitic diseases	0.606	0.394	0.000
F30 Manic episode	0.605	0.395	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.604	0.395	0.000
Q84 Other congenital malformations of integument	0.604	0.395	0.000
Q83 Congenital malformations of breast	0.604	0.395	0.000
Q81 Epidermolysis bullosa	0.604	0.395	0.000
Q80 Congenital ichthyosis	0.604	0.395	0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.000	0.396	0.604
M85.65 Other cyst of bone (Pelvic region and thigh)	0.604	0.396	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations