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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7169584
log Bayes Factor = 19.7428
Chromosome 15   position 78,822,660  (GRCh37) Explore rs7169584 on Ensembl!
Variant rs7169584 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
J44.9 Chronic obstructive pulmonary disease, unspecified
0.000 0.000 1.000
J44 Other chronic obstructive pulmonary disease
0.000 0.000 1.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.000 1.000
J40-J47 Chronic lower respiratory diseases
0.000 0.000 1.000
J43.9 Emphysema, unspecified
0.000 0.000 1.000
I71 Aortic aneurysm and dissection
0.000 0.000 1.000
J43 Emphysema
0.000 0.000 1.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.000 1.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.001 0.999
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.004 0.996
I73 Other peripheral vascular diseases
0.000 0.005 0.995
Chapter X Diseases of the respiratory system
0.000 0.006 0.994
J90-J94 Other diseases of pleura
0.000 0.008 0.992
I70 Atherosclerosis
0.000 0.009 0.991
J92 Pleural plaque
0.000 0.013 0.987
I73.9 Peripheral vascular disease, unspecified
0.000 0.013 0.987
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.014 0.986
I60-I69 Cerebrovascular diseases
0.000 0.018 0.982
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.018 0.982
J42 Unspecified chronic bronchitis
0.000 0.019 0.981
Chapter IX Diseases of the circulatory system
0.000 0.020 0.980
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.026 0.974
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.027 0.973
J92.0 Pleural plaque with presence of asbestos
0.000 0.029 0.971
J60-J70 Lung diseases due to external agents
0.000 0.034 0.966
I60 Subarachnoid haemorrhage
0.000 0.035 0.965
J95-J99 Other diseases of the respiratory system
0.000 0.040 0.960
I67 Other cerebrovascular diseases
0.000 0.042 0.958
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.051 0.949
I69 Sequelae of cerebrovascular disease
0.000 0.055 0.945
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.000 0.056 0.944
I26 Pulmonary embolism
0.000 0.063 0.937
I27 Other pulmonary heart diseases
0.000 0.063 0.937
J92.9 Pleural plaque without asbestos
0.000 0.065 0.935
J98 Other respiratory disorders
0.000 0.066 0.934
I77 Other disorders of arteries and arterioles
0.000 0.073 0.927
J98.1 Pulmonary collapse
0.000 0.077 0.923
J90 Pleural effusion, not elsewhere classified
0.000 0.078 0.922
I27.9 Pulmonary heart disease, unspecified
0.000 0.079 0.921
I67.9 Cerebrovascular disease, unspecified
0.000 0.088 0.912
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.095 0.905
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.096 0.904
I69.3 Sequelae of cerebral infarction
0.000 0.113 0.887
I73.0 Raynaud's syndrome
0.000 0.115 0.885
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.116 0.884
I72 Other aneurysm
0.000 0.119 0.881
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.139 0.861
I67.8 Other specified cerebrovascular diseases
0.000 0.146 0.854
J86 Pyothorax
0.000 0.148 0.852
I60.8 Other subarachnoid haemorrhage
0.000 0.153 0.847
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.167 0.833
I77.1 Stricture of artery
0.000 0.167 0.833
J43.2 Centrilobular emphysema
0.000 0.168 0.832
I67.1 Cerebral aneurysm, nonruptured
0.000 0.170 0.830
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.174 0.826
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.177 0.823
J93 Pneumothorax
0.000 0.178 0.822
J86.9 Pyothorax without fistula
0.000 0.181 0.819
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.182 0.818
J98.4 Other disorders of lung
0.000 0.182 0.818
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.184 0.816
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.192 0.808
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.197 0.803
I72.0 Aneurysm of carotid artery
0.000 0.197 0.803
I77.0 Arteriovenous fistula, acquired
0.000 0.201 0.799
I71.0 Dissection of aorta [any part]
0.000 0.214 0.786
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.215 0.785
I70.0 Atherosclerosis of aorta
0.000 0.233 0.767
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.235 0.765
J60 Coalworker's pneumoconiosis
0.000 0.236 0.764
J93.1 Other spontaneous pneumothorax
0.000 0.243 0.757
J98.9 Respiratory disorder, unspecified
0.000 0.243 0.757
J64 Unspecified pneumoconiosis
0.000 0.253 0.747
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.256 0.744
I72.8 Aneurysm of other specified arteries
0.000 0.265 0.735
I77.2 Rupture of artery
0.000 0.275 0.725
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.282 0.718
J41 Simple and mucopurulent chronic bronchitis
0.000 0.283 0.717
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.283 0.717
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.283 0.717
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.283 0.717
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.283 0.717
J43.1 Panlobular emphysema
0.000 0.283 0.717
J43.0 MacLeod's syndrome
0.000 0.283 0.717
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.287 0.713
I61 Intracerebral haemorrhage
0.000 0.288 0.711
I70.9 Generalised and unspecified atherosclerosis
0.000 0.289 0.711
I70.8 Atherosclerosis of other arteries
0.000 0.289 0.711
I28 Other diseases of pulmonary vessels
0.000 0.291 0.709
I78 Diseases of capillaries
0.000 0.294 0.706
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.296 0.704
I00-I02 Acute rheumatic fever
0.000 0.301 0.699
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.302 0.698
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.303 0.697
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.000 0.307 0.693
J66 Airway disease due to specific organic dust
0.000 0.307 0.693
J63 Pneumoconiosis due to other inorganic dusts
0.000 0.307 0.693
J62 Pneumoconiosis due to dust containing silica
0.000 0.307 0.693
J65 Pneumoconiosis associated with tuberculosis
0.000 0.307 0.693
J69 Pneumonitis due to solids and liquids
0.000 0.308 0.692
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.308 0.692
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.308 0.692
I27.8 Other specified pulmonary heart diseases
0.000 0.309 0.691
J96 Respiratory failure, not elsewhere classified
0.000 0.311 0.688
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.313 0.687
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.313 0.687
I67.5 Moyamoya disease
0.000 0.313 0.687
I67.4 Hypertensive encephalopathy
0.000 0.313 0.687
I67.3 Progressive vascular leukoencephalopathy
0.000 0.313 0.687
J98.2 Interstitial emphysema
0.000 0.317 0.683
I72.9 Aneurysm of unspecified site
0.000 0.324 0.676
I27.1 Kyphoscoliotic heart disease
0.000 0.328 0.672
J98.3 Compensatory emphysema
0.000 0.330 0.670
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.332 0.668
I77.5 Necrosis of artery
0.000 0.335 0.664
I77.4 Coeliac artery compression syndrome
0.000 0.335 0.664
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.337 0.663
I74 Arterial embolism and thrombosis
0.000 0.347 0.653
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.353 0.647
I27.0 Primary pulmonary hypertension
0.000 0.358 0.641
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.360 0.640
J70 Respiratory conditions due to other external agents
0.000 0.361 0.638
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.368 0.632
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.368 0.632
I72.1 Aneurysm of artery of upper extremity
0.000 0.368 0.632
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.370 0.630
I73.8 Other specified peripheral vascular diseases
0.000 0.375 0.625
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.379 0.621
J67 Hypersensitivity pneumonitis due to organic dust
0.000 0.380 0.620
J98.0 Diseases of bronchus, not elsewhere classified
0.000 0.380 0.620
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.381 0.619
J99.1 Respiratory disorders in other diffuse connective tissue disorders
0.000 0.387 0.613
J93.0 Spontaneous tension pneumothorax
0.000 0.389 0.611
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.394 0.606
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.397 0.603
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.401 0.599
I70.1 Atherosclerosis of renal artery
0.000 0.407 0.593
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.410 0.590
I79.1 Aortitis in diseases classified elsewhere
0.000 0.410 0.590
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.410 0.590
J98.6 Disorders of diaphragm
0.000 0.410 0.589
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.411 0.588
J85 Abscess of lung and mediastinum
0.000 0.412 0.588
J86.0 Pyothorax with fistula
0.000 0.419 0.581
J43.8 Other emphysema
0.000 0.423 0.577
J99.0 Rheumatoid lung disease
0.000 0.427 0.573
I72.3 Aneurysm of iliac artery
0.000 0.430 0.570
J40 Bronchitis, not specified as acute or chronic
0.000 0.437 0.563
I77.8 Other specified disorders of arteries and arterioles
0.000 0.442 0.558
J94 Other pleural conditions
0.000 0.444 0.555
I72.4 Aneurysm of artery of lower extremity
0.000 0.446 0.554
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.450 0.550
I77.3 Arterial fibromuscular dysplasia
0.000 0.452 0.547
I67.2 Cerebral atherosclerosis
0.000 0.457 0.543
I72.2 Aneurysm of renal artery
0.000 0.460 0.540
J93.8 Other pneumothorax
0.000 0.463 0.537
J69.8 Pneumonitis due to other solids and liquids
0.000 0.465 0.535
I27.2 Other secondary pulmonary hypertension
0.000 0.472 0.528
J95.8 Other postprocedural respiratory disorders
0.000 0.479 0.521
I28.8 Other specified diseases of pulmonary vessels
0.000 0.480 0.520
I77.6 Arteritis, unspecified
0.000 0.481 0.519
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.485 0.515
J41.8 Mixed simple and mucopurulent chronic bronchitis
0.000 0.486 0.514
J41.1 Mucopurulent chronic bronchitis
0.000 0.486 0.514
J41.0 Simple chronic bronchitis
0.000 0.486 0.514
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.490 0.510
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.490 0.510
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.490 0.510
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.490 0.510
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.491 0.508
I28.1 Aneurysm of pulmonary artery
0.000 0.491 0.508
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.491 0.508
I62 Other nontraumatic intracranial haemorrhage
0.000 0.492 0.508
I78.9 Disease of capillaries, unspecified
0.000 0.494 0.506
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.495 0.505
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.495 0.505
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.495 0.505
I68.0 Cerebral amyloid angiopathy
0.000 0.495 0.505
I05-I09 Chronic rheumatic heart diseases
0.000 0.498 0.502
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.498 0.502
I02 Rheumatic chorea
0.000 0.498 0.501
I01 Rheumatic fever with heart involvement
0.000 0.498 0.501
I00 Rheumatic fever without mention of heart involvement
0.000 0.502 0.498
J62.8 Pneumoconiosis due to other dust containing silica
0.000 0.503 0.497
J62.0 Pneumoconiosis due to talc dust
0.000 0.503 0.497
J63.8 Pneumoconiosis due to other specified inorganic dusts
0.000 0.503 0.497
J63.5 Stannosis
0.000 0.503 0.497
J63.4 Siderosis
0.000 0.503 0.497
J63.3 Graphite fibrosis (of lung)
0.000 0.503 0.497
J63.2 Berylliosis
0.000 0.503 0.497
J63.1 Bauxite fibrosis (of lung)
0.000 0.503 0.497
J63.0 Aluminosis (of lung)
0.000 0.503 0.497
J66.8 Airway disease due to other specific organic dusts
0.000 0.503 0.497
J66.2 Cannabinosis
0.000 0.503 0.497
J66.1 Flax-dresser's disease
0.000 0.503 0.497
J66.0 Byssinosis
0.000 0.503 0.497
J68.9 Unspecified respiratory condition due to chemicals, gases, fumes and vapours
0.000 0.503 0.497
J68.8 Other respiratory conditions due to chemicals, gases, fumes and vapours
0.000 0.503 0.497
J68.4 Chronic respiratory conditions due to chemicals, gases, fumes and vapours
0.000 0.503 0.497
J68.3 Other acute and subacute respiratory conditions due to chemicals, gases, fumes and vapours
0.000 0.503 0.497
J68.2 Upper respiratory inflammation due to chemicals, gases, fumes and vapours, not elsewhere classified
0.000 0.503 0.497
J68.1 Acute pulmonary oedema due to chemicals, gases, fumes and vapours
0.000 0.503 0.497
J68.0 Bronchitis and pneumonitis due to chemicals, gases, fumes and vapours
0.000 0.503 0.497
J69.1 Pneumonitis due to oils and essences
0.000 0.504 0.496
J96.9 Respiratory failure, unspecified
0.000 0.506 0.494
J96.1 Chronic respiratory failure
0.000 0.506 0.494
J96.0 Acute respiratory failure
0.000 0.506 0.494
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.507 0.493
I78.8 Other diseases of capillaries
0.000 0.514 0.486
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.517 0.483
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.519 0.481
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.521 0.479
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.523 0.477
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.524 0.476
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.524 0.476
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.524 0.476
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.524 0.476
J46 Status asthmaticus
0.000 0.524 0.476
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.527 0.473
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.532 0.468
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.533 0.467
I74.8 Embolism and thrombosis of other arteries
0.000 0.539 0.461
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.541 0.459
J95.5 Postprocedural subglottic stenosis
0.000 0.541 0.459
J95.4 Mendelson's syndrome
0.000 0.541 0.459
J95.3 Chronic pulmonary insufficiency following surgery
0.000 0.541 0.459
J95.2 Acute pulmonary insufficiency following nonthoracic surgery
0.000 0.541 0.459
J95.1 Acute pulmonary insufficiency following thoracic surgery
0.000 0.541 0.459
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.542 0.458
J70.9 Respiratory conditions due to unspecified external agent
0.000 0.542 0.458
J70.8 Respiratory conditions due to other specified external agents
0.000 0.542 0.458
J70.4 Drug-induced interstitial lung disorder, unspecified
0.000 0.542 0.458
J70.3 Chronic drug-induced interstitial lung disorders
0.000 0.542 0.458
J70.2 Acute drug-induced interstitial lung disorders
0.000 0.542 0.458
J70.0 Acute pulmonary manifestations due to radiation
0.000 0.542 0.458
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.550 0.450
J69.0 Pneumonitis due to food and vomit
0.000 0.553 0.447
J09-J18 Influenza and pneumonia
0.000 0.555 0.445
J67.8 Hypersensitivity pneumonitis due to other organic dusts
0.000 0.555 0.444
J67.7 Air-conditioner and humidifier lung
0.000 0.555 0.444
J67.6 Maple-bark-stripper's lung
0.000 0.555 0.444
J67.5 Mushroom-worker's lung
0.000 0.555 0.444
J67.4 Maltworker's lung
0.000 0.555 0.444
J67.3 Suberosis
0.000 0.555 0.444
J67.1 Bagassosis
0.000 0.555 0.444
J67.0 Farmer's lung
0.000 0.555 0.444
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.556 0.444
J91 Pleural effusion in conditions classified elsewhere
0.000 0.557 0.443
J99.8 Respiratory disorders in other diseases classified elsewhere
0.000 0.561 0.439
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.563 0.437
I74.5 Embolism and thrombosis of iliac artery
0.000 0.567 0.433
J98.8 Other specified respiratory disorders
0.000 0.569 0.430
J93.9 Pneumothorax, unspecified
0.000 0.571 0.429
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.575 0.425
J98.5 Diseases of mediastinum, not elsewhere classified
0.001 0.575 0.424
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.577 0.423
J85.1 Abscess of lung with pneumonia
0.000 0.577 0.423
J85.3 Abscess of mediastinum
0.000 0.578 0.421
J85.0 Gangrene and necrosis of lung
0.000 0.578 0.421
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.579 0.421
J67.9 Hypersensitivity pneumonitis due to unspecified organic dust
0.000 0.588 0.412
J67.2 Bird fancier's lung
0.000 0.589 0.410
J70.1 Chronic and other pulmonary manifestations due to radiation
0.000 0.596 0.403
I09 Other rheumatic heart diseases
0.000 0.596 0.403
J94.9 Pleural condition, unspecified
0.000 0.601 0.398
J94.0 Chylous effusion
0.000 0.601 0.398
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.602 0.398
J94.8 Other specified pleural conditions
0.000 0.602 0.398
J94.1 Fibrothorax
0.000 0.602 0.398
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.605 0.395
J95.9 Postprocedural respiratory disorder, unspecified
0.000 0.608 0.392
I61.8 Other intracerebral haemorrhage
0.000 0.609 0.391
J20-J22 Other acute lower respiratory infections
0.000 0.612 0.388
J95.0 Tracheostomy malfunction
0.000 0.616 0.384
I07 Rheumatic tricuspid valve diseases
0.000 0.616 0.384
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.640 0.359
I01.8 Other acute rheumatic heart disease
0.000 0.640 0.359
I01.2 Acute rheumatic myocarditis
0.000 0.640 0.359
I01.1 Acute rheumatic endocarditis
0.000 0.640 0.359
I01.0 Acute rheumatic pericarditis
0.000 0.640 0.359
I02.9 Rheumatic chorea without heart involvement
0.000 0.640 0.359
I02.0 Rheumatic chorea with heart involvement
0.000 0.640 0.359
J85.2 Abscess of lung without pneumonia
0.000 0.641 0.359
J96.09 Acute respiratory failure; Type unspecified
0.000 0.646 0.354
J96.01 Acute respiratory failure; Type II [hypercapnic]
0.000 0.646 0.354
J96.00 Acute respiratory failure; Type I [hypoxic]
0.000 0.646 0.354
J96.19 Chronic respiratory failure; Type unspecified
0.000 0.646 0.354
J96.11 Chronic respiratory failure; Type II [hypercapnic]
0.000 0.646 0.354
J96.10 Chronic respiratory failure; Type I [hypoxic]
0.000 0.646 0.354
J96.99 Respiratory failure, unspecified; Type unspecified
0.000 0.646 0.354
J96.91 Respiratory failure unspecified; Type II [hypercapnic]
0.000 0.646 0.354
J96.90 Respiratory failure, unspecified; Type I [hypoxic]
0.000 0.646 0.354
I05 Rheumatic mitral valve diseases
0.000 0.649 0.351
J10 Influenza due to identified influenza virus
0.000 0.651 0.349
J18 Pneumonia, organism unspecified
0.000 0.653 0.347
I78.1 Naevus, nonneoplastic
0.000 0.666 0.334
I06 Rheumatic aortic valve diseases
0.000 0.667 0.333
I09.9 Rheumatic heart disease, unspecified
0.000 0.667 0.333
J18.1 Lobar pneumonia, unspecified
0.000 0.667 0.333
I62.1 Nontraumatic extradural haemorrhage
0.000 0.672 0.327
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.000 0.681 0.319
J09 Influenza due to certain identified influenza virus
0.000 0.681 0.319
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.684 0.316
J13 Pneumonia due to Streptococcus pneumoniae
0.000 0.688 0.312
I70.10 Atherosclerosis of renal artery (without gangrene)
0.001 0.692 0.307
J80-J84 Other respiratory diseases principally affecting the interstitium
0.001 0.696 0.303
J17 Pneumonia in diseases classified elsewhere
0.000 0.698 0.302
I07.1 Tricuspid insufficiency
0.000 0.701 0.299
J15 Bacterial pneumonia, not elsewhere classified
0.000 0.704 0.296
I05.1 Rheumatic mitral insufficiency
0.000 0.704 0.296
I09.8 Other specified rheumatic heart diseases
0.000 0.710 0.289
I09.2 Chronic rheumatic pericarditis
0.000 0.710 0.289
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.710 0.289
I09.0 Rheumatic myocarditis
0.000 0.710 0.289
J12 Viral pneumonia, not elsewhere classified
0.000 0.715 0.285
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.716 0.284
I07.9 Tricuspid valve disease, unspecified
0.000 0.725 0.275
I07.8 Other tricuspid valve diseases
0.000 0.725 0.275
I07.2 Tricuspid stenosis with insufficiency
0.000 0.725 0.275
I07.0 Tricuspid stenosis
0.000 0.725 0.275
J45 Asthma
0.000 0.725 0.274
J21 Acute bronchiolitis
0.000 0.726 0.274
J10.1 Influenza with other respiratory manifestations, influenza virus identified
0.000 0.727 0.273
J17.0 Pneumonia in bacterial diseases classified elsewhere
0.000 0.731 0.269
J84 Other interstitial pulmonary diseases
0.000 0.735 0.265
J10.0 Influenza with pneumonia, influenza virus identified
0.000 0.741 0.259
J14 Pneumonia due to Haemophilus influenzae
0.000 0.744 0.256
J20 Acute bronchitis
0.000 0.747 0.253
I05.8 Other mitral valve diseases
0.000 0.748 0.252
I05.0 Mitral stenosis
0.000 0.748 0.252
J10.8 Influenza with other manifestations, influenza virus identified
0.000 0.750 0.250
J18.2 Hypostatic pneumonia, unspecified
0.000 0.751 0.249
J94.2 Haemothorax
0.001 0.755 0.244
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.761 0.239
I06.8 Other rheumatic aortic valve diseases
0.000 0.761 0.239
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.761 0.239
I06.1 Rheumatic aortic insufficiency
0.000 0.761 0.239
I99 Other and unspecified disorders of circulatory system
0.000 0.764 0.236
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.766 0.234
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.769 0.230
J16.8 Pneumonia due to other specified infectious organisms
0.000 0.771 0.229
J16.0 Chlamydial pneumonia
0.000 0.771 0.229
I05.2 Mitral stenosis with insufficiency
0.000 0.771 0.229
J15.2 Pneumonia due to staphylococcus
0.000 0.772 0.228
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.773 0.227
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.773 0.226
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.773 0.226
J18.8 Other pneumonia, organism unspecified
0.000 0.774 0.226
J00-J06 Acute upper respiratory infections
0.000 0.775 0.225
J15.8 Other bacterial pneumonia
0.000 0.775 0.225
J15.5 Pneumonia due to Escherichia coli
0.000 0.777 0.222
I10-I15 Hypertensive diseases
0.000 0.779 0.221
I63 Cerebral infarction
0.000 0.779 0.221
J15.4 Pneumonia due to other streptococci
0.000 0.783 0.217
J17.8 Pneumonia in other diseases classified elsewhere
0.000 0.783 0.217
J15.6 Pneumonia due to other aerobic Gram-negative bacteria
0.000 0.784 0.216
J15.3 Pneumonia due to streptococcus, group B
0.000 0.788 0.212
I06.0 Rheumatic aortic stenosis
0.000 0.788 0.211
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.791 0.209
J15.9 Bacterial pneumonia, unspecified
0.000 0.791 0.209
I95 Hypotension
0.000 0.793 0.207
J12.8 Other viral pneumonia
0.000 0.795 0.205
J12.3 Human metapneumovirus pneumonia
0.000 0.795 0.205
J12.2 Parainfluenza virus pneumonia
0.000 0.795 0.205
J12.1 Respiratory syncytial virus pneumonia
0.000 0.795 0.205
J12.0 Adenoviral pneumonia
0.000 0.795 0.205
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.795 0.204
Z72.0 Tobacco use
0.000 0.796 0.204
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.796 0.204
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.796 0.204
I98.0 Cardiovascular syphilis
0.000 0.796 0.204
Z72.1 Alcohol use
0.000 0.798 0.202
J84.1 Other interstitial pulmonary diseases with fibrosis
0.000 0.798 0.202
Z72 Problems related to lifestyle
0.000 0.801 0.199
J11 Influenza, virus not identified
0.000 0.802 0.197
J45.8 Mixed asthma
0.000 0.803 0.197
J45.1 Nonallergic asthma
0.000 0.803 0.197
J21.8 Acute bronchiolitis due to other specified organisms
0.000 0.803 0.197
J21.1 Acute bronchiolitis due to human metapneumovirus
0.000 0.803 0.197
J21.0 Acute bronchiolitis due to respiratory syncytial virus
0.000 0.803 0.197
J15.7 Pneumonia due to Mycoplasma pneumoniae
0.000 0.803 0.197
J18.9 Pneumonia, unspecified
0.000 0.805 0.195
I05.9 Mitral valve disease, unspecified
0.000 0.807 0.193
J17.1 Pneumonia in viral diseases classified elsewhere
0.000 0.807 0.193
J21.9 Acute bronchiolitis, unspecified
0.000 0.808 0.192
F17.1 Harmful use
0.000 0.810 0.190
J84.0 Alveolar and parietoalveolar conditions
0.000 0.810 0.190
J15.0 Pneumonia due to Klebsiella pneumoniae
0.000 0.811 0.189
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.811 0.189
J84.8 Other specified interstitial pulmonary diseases
0.000 0.812 0.188
I95.1 Orthostatic hypotension
0.000 0.815 0.185
J17.3 Pneumonia in parasitic diseases
0.000 0.817 0.182
J20.7 Acute bronchitis due to echovirus
0.000 0.818 0.181
J20.6 Acute bronchitis due to rhinovirus
0.000 0.818 0.181
J20.5 Acute bronchitis due to respiratory syncytial virus
0.000 0.818 0.181
J20.4 Acute bronchitis due to parainfluenza virus
0.000 0.818 0.181
J20.3 Acute bronchitis due to coxsackie virus
0.000 0.818 0.181
J20.2 Acute bronchitis due to streptococcus
0.000 0.818 0.181
J20.1 Acute bronchitis due to Haemophilus influenzae
0.000 0.818 0.181
J20.0 Acute bronchitis due to Mycoplasma pneumoniae
0.000 0.818 0.181
J20.8 Acute bronchitis due to other specified organisms
0.000 0.820 0.180
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.824 0.175
J15.1 Pneumonia due to Pseudomonas
0.000 0.828 0.172
J12.9 Viral pneumonia, unspecified
0.000 0.829 0.171
J00 Acute nasopharyngitis [common cold]
0.000 0.829 0.171
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.832 0.168
I95.8 Other hypotension
0.000 0.834 0.166
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.834 0.165
I97.0 Postcardiotomy syndrome
0.000 0.834 0.165
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.835 0.165
I15 Secondary hypertension
0.000 0.836 0.163
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.000 0.838 0.162
I13 Hypertensive heart and renal disease
0.000 0.841 0.159
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.841 0.159
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.841 0.159
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.841 0.159
J17.2 Pneumonia in mycoses
0.000 0.842 0.158
J20.9 Acute bronchitis, unspecified
0.000 0.843 0.157
I65.1 Occlusion and stenosis of basilar artery
0.001 0.845 0.155
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.845 0.155
Z72.2 Drug use
0.000 0.846 0.154
F17 Mental and behavioural disorders due to use of tobacco
0.000 0.854 0.146
Z72.6 Gambling and betting
0.000 0.857 0.143
Z72.5 High-risk sexual behaviour
0.000 0.857 0.143
Z72.3 Lack of physical exercise
0.000 0.857 0.143
Z72.4 Inappropriate diet and eating habits
0.000 0.857 0.143
J11.8 Influenza with other manifestations, virus not identified
0.000 0.858 0.142
Z72.8 Other problems related to lifestyle
0.000 0.859 0.141
J01 Acute sinusitis
0.000 0.859 0.140
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.861 0.139
F17.2 Dependence syndrome
0.000 0.861 0.139
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.861 0.139
I65.2 Occlusion and stenosis of carotid artery
0.000 0.863 0.137
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.865 0.134
I15.1 Hypertension secondary to other renal disorders
0.000 0.869 0.131
J04 Acute laryngitis and tracheitis
0.000 0.869 0.131
Z72.9 Problem related to lifestyle, unspecified
0.000 0.869 0.130
I97.1 Other functional disturbances following cardiac surgery
0.000 0.871 0.129
J45.0 Predominantly allergic asthma
0.000 0.873 0.127
J47 Bronchiectasis
0.000 0.873 0.127
I15.9 Seconday hypertension, unspecified
0.000 0.875 0.125
J02 Acute pharyngitis
0.000 0.875 0.125
J03 Acute tonsillitis
0.000 0.875 0.125
J81 Pulmonary oedema
0.000 0.876 0.124
I95.0 Idiopathic hypotension
0.000 0.877 0.123
I11 Hypertensive heart disease
0.000 0.879 0.121
I15.8 Other secondary hypertension
0.000 0.882 0.117
I15.2 Hypertension secondary to endocrine disorders
0.000 0.882 0.117
I87 Other disorders of veins
0.000 0.883 0.117
J05.0 Acute obstructive laryngitis [croup]
0.000 0.884 0.116
J05.1 Acute epiglottitis
0.000 0.884 0.116
I12 Hypertensive renal disease
0.000 0.884 0.116
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.886 0.114
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.886 0.114
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.886 0.114
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.886 0.114
J11.0 Influenza with pneumonia, virus not identified
0.001 0.887 0.112
I81 Portal vein thrombosis
0.000 0.888 0.112
I88 Nonspecific lymphadenitis
0.000 0.888 0.112
I85 Oesophageal varices
0.000 0.891 0.109
F17.8 Other mental and behavioural disorders
0.000 0.895 0.105
F17.7 Residual and late-onset psychotic disorder
0.000 0.895 0.105
F17.6 Amnesic syndrome
0.000 0.895 0.105
F17.5 Psychotic disorder
0.000 0.895 0.105
F17.4 Withdrawal state with delirium
0.000 0.895 0.105
F17.3 Withdrawal state
0.000 0.895 0.105
I87.1 Compression of vein
0.000 0.896 0.104
J82 Pulmonary eosinophilia, not elsewhere classified
0.002 0.897 0.101
I80 Phlebitis and thrombophlebitis
0.000 0.897 0.103
J01.0 Acute maxillary sinusitis
0.000 0.898 0.102
J01.8 Other acute sinusitis
0.000 0.899 0.101
J01.4 Acute pansinusitis
0.000 0.899 0.101
J01.3 Acute sphenoidal sinusitis
0.000 0.899 0.101
J01.1 Acute frontal sinusitis
0.000 0.899 0.101
J18.0 Bronchopneumonia, unspecified
0.000 0.899 0.100
F17.9 Unspecified mental and behavioural disorder
0.000 0.900 0.100
F17.0 Acute intoxication
0.000 0.901 0.098
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.000 0.903 0.097
I85.0 Oesophageal varices with bleeding
0.000 0.904 0.096
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.904 0.096
J01.2 Acute ethmoidal sinusitis
0.000 0.904 0.096
J06 Acute upper respiratory infections of multiple and unspecified sites
0.000 0.905 0.095
J04.2 Acute laryngotracheitis
0.000 0.906 0.094
I87.8 Other specified disorders of veins
0.000 0.907 0.093
J02.0 Streptococcal pharyngitis
0.000 0.907 0.093
I15.0 Renovascular hypertension
0.000 0.907 0.092
J04.1 Acute tracheitis
0.000 0.909 0.091
I63.8 Other cerebral infarction
0.000 0.910 0.090
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.910 0.089
J02.8 Acute pharyngitis due to other specified organisms
0.000 0.910 0.090
J03.8 Acute tonsillitis due to other specified organisms
0.000 0.910 0.089
J03.0 Streptococcal tonsillitis
0.000 0.910 0.089
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.911 0.089
J01.9 Acute sinusitis, unspecified
0.000 0.915 0.085
I87.9 Disorder of vein, unspecified
0.000 0.916 0.084
I87.0 Postphlebitic syndrome
0.000 0.916 0.084
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.000 0.916 0.084
J11.1 Influenza with other respiratory manifestations, virus not identified
0.001 0.918 0.082
I88.8 Other nonspecific lymphadenitis
0.000 0.920 0.080
I88.1 Chronic lymphadenitis, except mesenteric
0.000 0.920 0.080

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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