TreeWAS – Variant ID: rs7192797

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
N20.0 Calculus of kidney	1.000	0.000	0.000
N20 Calculus of kidney and ureter	1.000	0.000	0.000
N20.2 Calculus of kidney with calculus of ureter	0.999	0.001	0.000
N20.1 Calculus of ureter	0.999	0.001	0.000
N20-N23 Urolithiasis	0.702	0.298	0.000
N21 Calculus of lower urinary tract	0.683	0.317	0.000
N21.1 Calculus in urethra	0.642	0.358	0.000
N21.0 Calculus in bladder	0.632	0.368	0.000
N22 Calculus of urinary tract in diseases classified elsewhere	0.504	0.496	0.000
N21.9 Calculus of lower urinary tract, unspecified	0.489	0.510	0.000
N20.9 Urinary calculus, unspecified	0.453	0.547	0.000
N21.8 Other lower urinary tract calculus	0.422	0.577	0.000
N17.9 Acute renal failure, unspecified	0.000	0.603	0.397
N17 Acute renal failure	0.000	0.616	0.384
N18.3 Chronic kidney disease, stage 3	0.000	0.618	0.382
N18 Chronic renal failure	0.000	0.624	0.376
N17-N19 Renal failure	0.000	0.625	0.375
N22.8 Calculus of urinary tract in other diseases classified elsewhere	0.361	0.639	0.000
N22.0 Calculus of urinary tract in schistosomiasis [bilharziasis]	0.361	0.639	0.000
N18.4 Chronic kidney disease, stage 4	0.000	0.658	0.342
N19 Unspecified renal failure	0.000	0.696	0.304
N18.1 Chronic kidney disease, stage 1	0.000	0.700	0.300
N18.9 Chronic renal failure, unspecified	0.000	0.716	0.284
N17.0 Acute renal failure with tubular necrosis	0.000	0.723	0.277
N17.2 Acute renal failure with medullary necrosis	0.000	0.724	0.275
N17.1 Acute renal failure with acute cortical necrosis	0.000	0.724	0.275
N17.8 Other acute renal failure	0.000	0.725	0.275
N18.5 Chronic kidney disease, stage 5	0.000	0.745	0.255
N18.8 Other chronic renal failure	0.000	0.771	0.229
N18.0 End-stage renal disease	0.000	0.807	0.193
N18.2 Chronic kidney disease, stage 2	0.000	0.870	0.130
N23 Unspecified renal colic	0.109	0.891	0.000
N03.9 Unspecified	0.000	0.962	0.038
I12.0 Hypertensive renal disease with renal failure	0.000	0.966	0.034
I12 Hypertensive renal disease	0.000	0.971	0.029
I10 Essential (primary) hypertension	0.000	0.976	0.024
I10-I15 Hypertensive diseases	0.000	0.976	0.024
I12.9 Hypertensive renal disease without renal failure	0.000	0.977	0.023
I15 Secondary hypertension	0.000	0.981	0.019
I15.1 Hypertension secondary to other renal disorders	0.000	0.982	0.018
I13 Hypertensive heart and renal disease	0.000	0.984	0.016
I15.8 Other secondary hypertension	0.000	0.986	0.014
I15.2 Hypertension secondary to endocrine disorders	0.000	0.986	0.014
I15.9 Seconday hypertension, unspecified	0.000	0.986	0.013
N03 Chronic nephritic syndrome	0.000	0.987	0.013
I11 Hypertensive heart disease	0.000	0.987	0.013
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.988	0.012
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.988	0.012
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.988	0.012
I15.0 Renovascular hypertension	0.000	0.989	0.011
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.989	0.010
N03.7 Diffuse crescentic glomerulonephritis	0.000	0.990	0.010
N03.6 Dense deposit disease	0.000	0.990	0.010
N03.4 Diffuse endocapillary proliferative glomerulonephritis	0.000	0.990	0.010
N03.3 Diffuse mesangial proliferative glomerulonephritis	0.000	0.990	0.010
N03.2 Diffuse membranous glomerulonephritis	0.000	0.990	0.010
N03.0 Minor glomerular abnormality	0.000	0.990	0.010
N03.8 Other	0.000	0.990	0.009
N03.1 Focal and segmental glomerular lesions	0.000	0.991	0.009
N03.5 Diffuse mesangiocapillary glomerulonephritis	0.000	0.991	0.009
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.992	0.008
Z47.8 Other specified orthopaedic follow-up care	0.000	0.992	0.008
I67.1 Cerebral aneurysm, nonruptured	0.000	0.992	0.008
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.993	0.007
H20.9 Iridocyclitis, unspecified	0.000	0.994	0.006
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.005	0.995	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.005	0.995	0.000
C90.0 Multiple myeloma	0.000	0.995	0.005
M24.4 Recurrent dislocation and subluxation of joint	0.004	0.996	0.000
O14.9 Preeclampsia, unspecified	0.000	0.996	0.004
Q51.3 Bicornate uterus	0.000	0.996	0.004
J35.1 Hypertrophy of tonsils	0.004	0.996	0.000
D84.9 Immunodeficiency, unspecified	0.004	0.996	0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.003	0.996	0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.000	0.997	0.003
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.003	0.997	0.000
A08.4 Viral intestinal infection, unspecified	0.003	0.997	0.000
H57.8 Other specified disorders of eye and adnexa	0.003	0.997	0.000
D84.1 Defects in the complement system	0.003	0.997	0.000
D84 Other immunodeficiencies	0.003	0.997	0.000
Q51 Congenital malformations of uterus and cervix	0.000	0.997	0.003
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.000	0.997	0.003
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.003	0.997	0.000
N97.9 Female infertility, unspecified	0.003	0.997	0.000
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.003	0.997	0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.003	0.997	0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.003	0.997	0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.003	0.997	0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.003	0.997	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.000	0.997	0.003
S62.60 Fracture of other finger (closed)	0.000	0.997	0.003
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.003	0.997	0.000
M82.1 Osteoporosis in endocrine disorders	0.000	0.997	0.003
R74.8 Abnormal levels of other serum enzymes	0.000	0.997	0.003
L60.9 Nail disorder, unspecified	0.000	0.997	0.003
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.003	0.997	0.000
M50.2 Other cervical disk displacement	0.000	0.997	0.003
M24.56 Contracture of joint (Lower leg)	0.003	0.997	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.003	0.997	0.000
H53.0 Amblyopia ex anopsia	0.003	0.997	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.000	0.997	0.003
D80 Immunodeficiency with predominantly antibody defects	0.003	0.997	0.000
Q54.0 Hypospadias, balanic	0.000	0.997	0.003
Q54 Hypospadias	0.000	0.997	0.003
L60 Nail disorders	0.000	0.997	0.003
C90 Multiple myeloma and malignant plasma cell neoplasms	0.000	0.997	0.003
M47.89 Other spondylosis (Site unspecified)	0.000	0.997	0.003
B02.9 Zoster without complication	0.003	0.997	0.000
D84.8 Other specified immunodeficiencies	0.002	0.997	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.002	0.997	0.000
L60.2 Onychogryphosis	0.000	0.997	0.003
M24.5 Contracture of joint	0.003	0.997	0.000
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.000	0.997	0.002
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.000	0.997	0.002
Q51.6 Embryonic cyst of cervix	0.000	0.997	0.002
Q51.5 Agenesis and aplasia of cervix	0.000	0.997	0.002
Q51.4 Unicornate uterus	0.000	0.997	0.002
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.000	0.997	0.002
Q51.0 Agenesis and aplasia of uterus	0.000	0.997	0.002
Q51.2 Other doubling of uterus	0.000	0.997	0.002
Q54.1 Hypospadias, penile	0.000	0.997	0.002
Z98.1 Arthrodesis status	0.002	0.998	0.000
L60.3 Nail dystrophy	0.000	0.998	0.002
L60.0 Ingrowing nail	0.000	0.998	0.002
D86.1 Sarcoidosis of lymph nodes	0.002	0.998	0.000
M82.19 Osteoporosis in endocrine disorders (Site unspecified)	0.000	0.998	0.002
M82.18 Osteoporosis in endocrine disorders (Other)	0.000	0.998	0.002
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)	0.000	0.998	0.002
M82.16 Osteoporosis in endocrine disorders (Lower leg)	0.000	0.998	0.002
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)	0.000	0.998	0.002
M82.14 Osteoporosis in endocrine disorders (Hand)	0.000	0.998	0.002
M82.13 Osteoporosis in endocrine disorders (Forearm)	0.000	0.998	0.002
M82.12 Osteoporosis in endocrine disorders (Upper arm)	0.000	0.998	0.002
M24.57 Contracture of joint (Ankle and foot)	0.002	0.998	0.000
C90.2 Plasmacytoma, extramedullary	0.000	0.998	0.002
Q50-Q56 Congenital malformations of genital organs	0.000	0.998	0.002
I27.2 Other secondary pulmonary hypertension	0.000	0.998	0.002
L60.8 Other nail disorders	0.000	0.998	0.002
Q54.9 Hypospadias, unspecified	0.000	0.998	0.002
M24.51 Contracture of joint (Shoulder region)	0.002	0.998	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.002	0.998	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.002	0.998	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.002	0.998	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.002	0.998	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.002	0.998	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.002	0.998	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.002	0.998	0.000
D80-D89 Certain disorders involving the immune mechanism	0.002	0.998	0.000
Q54.8 Other hypospadias	0.000	0.998	0.002
Q54.4 Congenital chordee	0.000	0.998	0.002
Q54.3 Hypospadias, perineal	0.000	0.998	0.002
Q54.2 Hypospadias, penoscrotal	0.000	0.998	0.002
M76.67 Achilles tendinitis (Ankle and foot)	0.000	0.998	0.002
L60.5 Yellow nail syndrome	0.000	0.998	0.002
L60.4 Beau's lines	0.000	0.998	0.002
L60.1 Onycholysis	0.000	0.998	0.002
H57 Other disorders of eye and adnexa	0.002	0.998	0.000
Q23.1 Congenital insufficiency of aortic valve	0.000	0.998	0.002
M24.54 Contracture of joint (Hand)	0.002	0.998	0.000
C90.3 Solitary plasmacytoma	0.000	0.998	0.002
C90.1 Plasma cell leukaemia	0.000	0.998	0.002
H57.1 Ocular pain	0.002	0.998	0.000
Q55 Other congenital malformations of male genital organs	0.000	0.998	0.002
M24.59 Contracture of joint (Site unspecified)	0.002	0.998	0.000
M24.58 Contracture of joint (Other)	0.002	0.998	0.000
M24.53 Contracture of joint (Forearm)	0.002	0.998	0.000
M24.52 Contracture of joint (Upper arm)	0.002	0.998	0.000
M24.50 Contracture of joint (Multiple sites)	0.002	0.998	0.000
R25.1 Tremor, unspecified	0.000	0.998	0.002
M24.55 Contracture of joint (Pelvic region and thigh)	0.002	0.998	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.000	0.998	0.002
R25.2 Cramp and spasm	0.000	0.998	0.002
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.002	0.998	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.000	0.998	0.002
Q55.2 Other congenital malformations of testis and scrotum	0.000	0.998	0.002
C55 Malignant neoplasm of uterus, part unspecified	0.002	0.998	0.000
M24.07 Loose body in joint (Ankle and foot)	0.002	0.998	0.000
Q53 Undescended testicle	0.000	0.998	0.002
J93.1 Other spontaneous pneumothorax	0.002	0.998	0.000
M24 Other specific joint derangements	0.002	0.998	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.000	0.998	0.002
D86 Sarcoidosis	0.002	0.998	0.000
Z63.7 Other stressful life events affecting family and household	0.002	0.998	0.000
D83 Common variable immunodeficiency	0.002	0.998	0.000
M24.24 Disorder of ligament (Hand)	0.002	0.998	0.000
B02.3 Zoster ocular disease	0.002	0.998	0.000
D04.3 Skin of other and unspecified parts of face	0.000	0.998	0.002
R25.3 Fasciculation	0.000	0.998	0.002
D24 Benign neoplasm of breast	0.000	0.998	0.002
D81 Combined immunodeficiencies	0.002	0.998	0.000
Q52 Other congenital malformations of female genitalia	0.000	0.998	0.002
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.000	0.998	0.002
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.998	0.002
H57.9 Disorder of eye and adnexa, unspecified	0.002	0.998	0.000
Q53.1 Undescended testicle, unilateral	0.000	0.998	0.002
Q55.9 Congenital malformation of male genital organ, unspecified	0.000	0.998	0.002
Q55.8 Other specified congenital malformations of male genital organs	0.000	0.998	0.002
Q55.6 Other congenital malformations of penis	0.000	0.998	0.002
Q55.5 Congenital absence and aplasia of penis	0.000	0.998	0.002
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.000	0.998	0.002
Q55.3 Atresia of vas deferens	0.000	0.998	0.002
Q55.1 Hypoplasia of testis and scrotum	0.000	0.998	0.002
Q55.0 Absence and aplasia of testis	0.000	0.998	0.002
R25 Abnormal involuntary movements	0.000	0.998	0.002
O14.0 Moderate preeclampsia	0.000	0.998	0.002
B02 Zoster [herpes zoster]	0.002	0.998	0.000
E46 Unspecified protein-energy malnutrition	0.000	0.998	0.002
O14.1 Severe preeclampsia	0.000	0.998	0.002
D82 Immunodeficiency associated with other major defects	0.002	0.998	0.000
B02.1 Zoster meningitis	0.002	0.998	0.000
D35.0 Adrenal gland	0.002	0.998	0.000
R23.8 Other and unspecified skin changes	0.002	0.998	0.000
A04.7 Enterocolitis due to Clostridium difficile	0.000	0.998	0.002
D75.2 Essential thrombocytosis	0.002	0.998	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.002	0.998	0.000
O14.2 HELLP syndrome	0.000	0.998	0.002
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
M24.2 Disorder of ligament	0.002	0.998	0.000
C16.0 Cardia	0.002	0.998	0.000
D83.9 Common variable immunodeficiency, unspecified	0.002	0.998	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.998	0.002
O73.0 Retained placenta, without haemorrhage	0.002	0.998	0.000
Q53.9 Undescended testicle, unspecified	0.000	0.998	0.001
Q53.0 Ectopic testis	0.000	0.998	0.001
D35.2 Pituitary gland	0.002	0.998	0.000
M24.9 Joint derangement, unspecified	0.002	0.998	0.000
Q56.4 Indeterminate sex, unspecified	0.000	0.998	0.001
Q56.3 Pseudohermaphroditism, unspecified	0.000	0.998	0.001
Q56.2 Female pseudohermaphroditism, not elsewhere classified	0.000	0.998	0.001
Q56.1 Male pseudohermaphroditism, not elsewhere classified	0.000	0.998	0.001
Q56.0 Hermaphroditism, not elsewhere classified	0.000	0.998	0.001
S00.0 Superficial injury of scalp	0.000	0.998	0.002
M24.0 Loose body in joint	0.002	0.998	0.000
W17.4 Street and highway	0.002	0.998	0.000
Z63.0 Problems in relationship with spouse or partner	0.002	0.998	0.000
D83.8 Other common variable immunodeficiencies	0.001	0.998	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.001	0.998	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.001	0.998	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.001	0.998	0.000
M24.26 Disorder of ligament (Lower leg)	0.002	0.998	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.002	0.998	0.000
B02.8 Zoster with other complications	0.002	0.998	0.000
D04.4 Skin of scalp and neck	0.000	0.998	0.002
D81.9 Combined immunodeficiency, unspecified	0.001	0.998	0.000
D81.8 Other combined immunodeficiencies	0.001	0.998	0.000
D81.7 Major histocompatibility complex class II deficiency	0.001	0.998	0.000
D81.6 Major histocompatibility complex class I deficiency	0.001	0.998	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.001	0.998	0.000
D81.4 Nezelof's syndrome	0.001	0.998	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.001	0.998	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.001	0.998	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.001	0.998	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.001	0.998	0.000
Q52.9 Congenital malformation of female genitalia, unspecified	0.000	0.998	0.001
Q52.8 Other specified congenital malformations of female genitalia	0.000	0.998	0.001
Q52.7 Other congenital malformations of vulva	0.000	0.998	0.001
Q52.6 Congenital malformation of clitoris	0.000	0.998	0.001
Q52.4 Other congenital malformations of vagina	0.000	0.998	0.001
Q52.3 Imperforate hymen	0.000	0.998	0.001
Q52.2 Congenital rectovaginal fistula	0.000	0.998	0.001
Q52.1 Doubling of vagina	0.000	0.998	0.001
Q52.0 Congenital absence of vagina	0.000	0.998	0.001
Z99.3 Dependence on wheelchair	0.000	0.998	0.002
H20 Iridocyclitis	0.000	0.998	0.002
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.000	0.998	0.002
M24.21 Disorder of ligament (Shoulder region)	0.001	0.998	0.000
D75.1 Secondary polycythaemia	0.002	0.998	0.000
N97.0 Female infertility associated with anovulation	0.002	0.998	0.000
O23.5 Infections of the genital tract in pregnancy	0.000	0.998	0.002
R25.0 Abnormal head movements	0.000	0.998	0.001
N97 Female infertility	0.002	0.998	0.000
M24.06 Loose body in joint-Lower leg	0.001	0.998	0.000
D86.0 Sarcoidosis of lung	0.002	0.998	0.000
M24.7 Protrusio acetabuli	0.001	0.998	0.000
B02.7 Disseminated zoster	0.001	0.998	0.000
B02.0 Zoster encephalitis	0.001	0.998	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.001	0.998	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.001	0.998	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.001	0.998	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.001	0.998	0.000
D82.2 Immunodeficiency with short-limbed stature	0.001	0.998	0.000
D82.0 Wiskott-Aldrich syndrome	0.001	0.998	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.998	0.002
F60.7 Dependent personality disorder	0.001	0.998	0.000
K07.1 Anomalies of jaw-cranial base relationship	0.000	0.998	0.002
M24.6 Ankylosis of joint	0.001	0.998	0.000
Q53.2 Undescended testicle, bilateral	0.000	0.998	0.001
F60.5 Anankastic personality disorder	0.001	0.998	0.000
M24.29 Disorder of ligament (Site unspecified)	0.001	0.998	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.001	0.998	0.000
M24.22 Disorder of ligament (Upper arm)	0.001	0.998	0.000
M24.20 Disorder of ligament (Multiple sites)	0.001	0.998	0.000
S22.30 Fracture of rib (closed)	0.002	0.998	0.000
D86.3 Sarcoidosis of skin	0.001	0.998	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.998	0.002
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.001	0.998	0.000
Q52.5 Fusion of labia	0.000	0.998	0.001
Z63.8 Other specified problems related to primary support group	0.001	0.998	0.000
Z63 Other problems related to primary support group, including family circumstances	0.002	0.998	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.001	0.998	0.000
M24.99 Joint derangement, unspecified (Site unspecified)	0.001	0.999	0.000
M24.98 Joint derangement, unspecified (Other)	0.001	0.999	0.000
M24.97 Joint derangement, unspecified (Ankle and foot)	0.001	0.999	0.000
M24.96 Joint derangement, unspecified (Lower leg)	0.001	0.999	0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M24.94 Joint derangement, unspecified (Hand)	0.001	0.999	0.000
M24.93 Joint derangement, unspecified (Forearm)	0.001	0.999	0.000
M24.92 Joint derangement, unspecified (Upper arm)	0.001	0.999	0.000
M24.91 Joint derangement, unspecified (Shoulder region)	0.001	0.999	0.000
M24.90 Joint derangement, unspecified (Multiple sites)	0.001	0.999	0.000
D86.8 Sarcoidosis of other and combined sites	0.001	0.999	0.000
F60.3 Emotionally unstable personality disorder	0.001	0.999	0.000
M76.6 Achilles tendinitis	0.000	0.999	0.001
X59.3 Sports and athletics area	0.001	0.999	0.000
F60 Specific personality disorders	0.001	0.999	0.000
M24.09 Loose body in joint (Site unspecified)	0.001	0.999	0.000
M24.08 Loose body in joint (Other)	0.001	0.999	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.001	0.999	0.000
M24.04 Loose body in joint (Hand)	0.001	0.999	0.000
M24.00 Loose body in joint (Multiple sites)	0.001	0.999	0.000
G95.2 Cord compression, unspecified	0.000	0.999	0.001
Q50.5 Embryonic cyst of broad ligament	0.000	0.999	0.001
D04.9 Skin, unspecified	0.000	0.999	0.001
D82.1 Di George's syndrome	0.001	0.999	0.000
H20.2 Lens-induced iridocyclitis	0.000	0.999	0.001
H57.0 Anomalies of pupillary function	0.001	0.999	0.000
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.000	0.999	0.001
Q50.3 Other congenital malformations of ovary	0.000	0.999	0.001
Q50.2 Congenital torsion of ovary	0.000	0.999	0.001
Q50.1 Developmental ovarian cyst	0.000	0.999	0.001
Q50.0 Congenital absence of ovary	0.000	0.999	0.001
S93.1 Dislocation of toe(s)	0.000	0.999	0.001
Z63.5 Disruption of family by separation and divorce	0.001	0.999	0.000
M24.28 Disorder of ligament (Other)	0.001	0.999	0.000
K04.9 Other and unspecified diseases of pulp and periapical tissues	0.001	0.999	0.000
N97.4 Female infertility associated with male factors	0.001	0.999	0.000
N97.3 Female infertility of cervical origin	0.001	0.999	0.000
N97.2 Female infertility of uterine origin	0.001	0.999	0.000
N97.1 Female infertility of tubal origin	0.001	0.999	0.000
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.001	0.999	0.000
M24.79 Protrusio acetabuli-Site unspec	0.001	0.999	0.000
M24.78 Protrusio acetabuli-Other	0.001	0.999	0.000
M24.77 Protrusio acetabuli-Ankle/foot	0.001	0.999	0.000
M24.76 Protrusio acetabuli-Lower leg	0.001	0.999	0.000
M24.74 Protrusio acetabuli-Hand	0.001	0.999	0.000
M24.73 Protrusio acetabuli-Forearm	0.001	0.999	0.000
M24.72 Protrusio acetabuli-Upper arm	0.001	0.999	0.000
M24.71 Protrusio acetabuli-Shldr region	0.001	0.999	0.000
M24.70 Protrusio acetabuli-Mult sites	0.001	0.999	0.000
R27.8 Other and unspecified lack of coordination	0.000	0.999	0.001
M24.69 Ankylosis of joint (Site unspecified)	0.001	0.999	0.000
M24.68 Ankylosis of joint (Other)	0.001	0.999	0.000
M24.64 Ankylosis of joint (Hand)	0.001	0.999	0.000
M24.63 Ankylosis of joint (Forearm)	0.001	0.999	0.000
M24.62 Ankylosis of joint (Upper arm)	0.001	0.999	0.000
M24.61 Ankylosis of joint (Shoulder region)	0.001	0.999	0.000
M24.60 Ankylosis of joint (Multiple sites)	0.001	0.999	0.000
D22.0 Melanocytic naevi of lip	0.000	0.999	0.001
H20.1 Chronic iridocyclitis	0.000	0.999	0.001
H58.8 Visual disturbances in diseases classified elsewhere	0.001	0.999	0.000
J69.0 Pneumonitis due to food and vomit	0.000	0.999	0.001
K86.0 Alcohol-induced chronic pancreatitis	0.001	0.999	0.000
M24.66 Ankylosis of joint (Lower leg)	0.001	0.999	0.000
C71.2 Temporal lobe	0.000	0.999	0.001
E66.8 Other obesity	0.001	0.999	0.000
E80.4 Gilbert's syndrome	0.001	0.999	0.000
M24.03 Loose body in joint (Forearm)	0.001	0.999	0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.001	0.999	0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.001	0.999	0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.001	0.999	0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.001	0.999	0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.001	0.999	0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.001	0.999	0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.001	0.999	0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.001	0.999	0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.001	0.999	0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.001	0.999	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.001	0.999	0.000
E53.8 Deficiency of other specified B group vitamins	0.001	0.999	0.000
N75.1 Abscess of Bartholin's gland	0.001	0.999	0.000
Z63.9 Problem related to primary support group, unspecified	0.001	0.999	0.000
Z63.3 Absence of family member	0.001	0.999	0.000
Z63.2 Inadequate family support	0.001	0.999	0.000
Z63.1 Problems in relationship with parents and in-laws	0.001	0.999	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.000	0.999	0.001
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.001	0.999	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.001	0.999	0.000
M76.69 Achilles tendinitis-Site unspec	0.000	0.999	0.001
M76.68 Achilles tendinitis-Other	0.000	0.999	0.001
M76.65 Achilles tendinitis-Pelvic/Thigh	0.000	0.999	0.001
M76.64 Achilles tendinitis-Hand	0.000	0.999	0.001
M76.63 Achilles tendinitis-Forearm	0.000	0.999	0.001
M76.62 Achilles tendinitis-Upper arm	0.000	0.999	0.001
M76.61 Achilles tendinitis-Shldr region	0.000	0.999	0.001
M76.60 Achilles tendinitis (Multiple sites)	0.000	0.999	0.001
F60.8 Other specific personality disorders	0.001	0.999	0.000
F60.4 Histrionic personality disorder	0.001	0.999	0.000
F60.2 Dissocial personality disorder	0.001	0.999	0.000
F60.1 Schizoid personality disorder	0.001	0.999	0.000
F60.0 Paranoid personality disorder	0.001	0.999	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.000	0.999	0.001
O71.8 Other specified obstetric trauma	0.001	0.999	0.000
Q87.4 Marfan's syndrome	0.001	0.999	0.000
M82 Osteoporosis in diseases classified elsewhere	0.000	0.999	0.001
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.001	0.999	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.001	0.999	0.000
M76.86 Other enthesopathies of lower limb, excluding foot (Lower leg)	0.000	0.999	0.001
L30.8 Other specified dermatitis	0.001	0.999	0.000
Y45.1 Salicylates	0.001	0.999	0.000
A08 Viral and other specified intestinal infections	0.001	0.999	0.000
D04 Carcinoma in situ of skin	0.000	0.999	0.001
Q38.7 Pharyngeal pouch	0.000	0.999	0.001
Z84.8 Family history of other specified conditions	0.000	0.999	0.001
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.001	0.999	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.001	0.999	0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.001	0.999	0.000
M25.96 Joint disorder, unspecified (Lower leg)	0.000	0.999	0.001
D04.5 Skin of trunk	0.000	0.999	0.001
N00-N08 Glomerular diseases	0.000	0.999	0.001
M24.75 Protrusio acetabuli-Pelvic/thigh	0.001	0.999	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.001	0.999	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.001	0.999	0.000
M24.01 Loose body in joint (Shoulder region)	0.001	0.999	0.000
M76.66 Achilles tendinitis (Lower leg)	0.000	0.999	0.001
M76.87 Other enthesopathies of lower limb, excluding foot (Ankle and foot)	0.000	0.999	0.001
C54.9 Corpus uteri, unspecified	0.001	0.999	0.000
F68.1 Intentional production or feigning of symptoms or disabilities, either physical or psychological [factitious disorder]	0.001	0.999	0.000
H20.8 Other iridocyclitis	0.000	0.999	0.001
K58.0 Irritable bowel syndrome with diarrhoea	0.000	0.999	0.001
L71.9 Rosacea, unspecified	0.000	0.999	0.001
O72.0 Third-stage haemorrhage	0.000	0.999	0.001
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.001	0.999	0.000
Q23 Congenital malformations of aortic and mitral valves	0.000	0.999	0.001
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.001	0.999	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.001	0.999	0.000
M24.67 Ankylosis of joint (Ankle and foot)	0.001	0.999	0.000
C71.9 Brain, unspecified	0.000	0.999	0.001
C71.3 Parietal lobe	0.000	0.999	0.001
F60.9 Personality disorder, unspecified	0.001	0.999	0.000
N97.8 Female infertility of other origin	0.001	0.999	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.000	0.999	0.001
A08.5 Other specified intestinal infections	0.001	0.999	0.000
A08.2 Adenoviral enteritis	0.001	0.999	0.000
A08.0 Rotaviral enteritis	0.001	0.999	0.000
D04.8 Skin of other sites	0.000	0.999	0.001
D04.0 Skin of lip	0.000	0.999	0.001
F60.6 Anxious [avoidant] personality disorder	0.001	0.999	0.000
M82.8 Osteoporosis in other diseases classified elsewhere	0.000	0.999	0.001
M82.0 Osteoporosis in multiple myelomatosis	0.000	0.999	0.001
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.000	0.999	0.001
R25.8 Other and unspecified abnormal involuntary movements	0.000	0.999	0.001
Z63.6 Dependent relative needing care at home	0.001	0.999	0.000
J13 Pneumonia due to Streptococcus pneumoniae	0.001	0.999	0.000
B02.2 Zoster with other nervous system involvement	0.001	0.999	0.000
D04.1 Skin of eyelid, including canthus	0.000	0.999	0.001
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.001	0.999	0.000
D89.3 Immune reconstitution syndrome	0.001	0.999	0.000
E53.9 Vitamin B deficiency, unspecified	0.001	0.999	0.000
G12.2 Motor neuron disease	0.000	0.999	0.001
J95.8 Other postprocedural respiratory disorders	0.000	0.999	0.001
M76.8 Other enthesopathies of lower limb, excluding foot	0.000	0.999	0.001
A08.3 Other viral enteritis	0.001	0.999	0.000
E61.1 Iron deficiency	0.000	0.999	0.001
M50.0 Cervical disk disorder with myelopathy	0.000	0.999	0.001
Q27.3 Peripheral arteriovenous malformation	0.000	0.999	0.001
Z63.4 Disappearance and death of family member	0.001	0.999	0.000
N07 Hereditary nephropathy, not elsewhere classified	0.000	0.999	0.001
N06 Isolated proteinuria with specified morphological lesion	0.000	0.999	0.001
N01 Rapidly progressive nephritic syndrome	0.000	0.999	0.001
N00 Acute nephritic syndrome	0.000	0.999	0.001
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.001	0.999	0.000
C57.8 Overlapping lesion of female genital organs	0.001	0.999	0.000
E80.1 Porphyria cutanea tarda	0.001	0.999	0.000
H58.9 Other specified disorders of eye and adnexa in diseases classified elsewhere	0.001	0.999	0.000
H58.1 Visual disturbances in diseases classified elsewhere	0.001	0.999	0.000
H58.0 Anomalies of pupillary function in diseases classified elsewhere	0.001	0.999	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.000	0.999	0.001
Q23.8 Other congenital malformations of aortic and mitral valves	0.000	0.999	0.001
Q23.4 Hypoplastic left heart syndrome	0.000	0.999	0.001
Q23.3 Congenital mitral insufficiency	0.000	0.999	0.001
Q23.2 Congenital mitral stenosis	0.000	0.999	0.001
R45.2 Unhappiness	0.000	0.999	0.001
F68 Other disorders of adult personality and behaviour	0.001	0.999	0.000
I74 Arterial embolism and thrombosis	0.000	0.999	0.001
S12.90 Fracture of neck, part unspecified (closed)	0.000	0.999	0.001
D89.1 Cryoglobulinaemia	0.001	0.999	0.000
L71.1 Rhinophyma	0.000	0.999	0.001
W22.9 Unspecified place	0.000	0.999	0.001
M82.09 Osteoporosis in multiple myelomatosis (Site unspecified)	0.000	0.999	0.001
M82.08 Osteoporosis in multiple myelomatosis (Other)	0.000	0.999	0.001
M82.07 Osteoporosis in multiple myelomatosis (Ankle and foot)	0.000	0.999	0.001
M82.06 Osteoporosis in multiple myelomatosis (Lower leg)	0.000	0.999	0.001
M82.05 Osteoporosis in multiple myelomatosis (Pelvic region and thigh)	0.000	0.999	0.001
M82.04 Osteoporosis in multiple myelomatosis (Hand)	0.000	0.999	0.001
M82.03 Osteoporosis in multiple myelomatosis (Forearm)	0.000	0.999	0.001
M82.02 Osteoporosis in multiple myelomatosis (Upper arm)	0.000	0.999	0.001
M82.01 Osteoporosis in multiple myelomatosis (Shoulder region)	0.000	0.999	0.001
M82.00 Osteoporosis in multiple myelomatosis (Multiple sites)	0.000	0.999	0.001
M82.89 Osteoporosis in other diseases classified elsewhere (Site unspecified)	0.000	0.999	0.001
M82.88 Osteoporosis in other diseases classified elsewhere (Other)	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations