TreeWAS – Variant ID: rs7193778

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.000	0.971	0.029
K80.0 Calculus of gallbladder with acute cholecystitis	0.000	0.978	0.022
K80 Cholelithiasis	0.000	0.978	0.022
E11.9 Without complications	0.000	0.979	0.021
E04.1 Non-toxic single thyroid nodule	0.019	0.981	0.000
K80.4 Calculus of bile duct with cholecystitis	0.000	0.982	0.018
K80.1 Calculus of gallbladder with other cholecystitis	0.000	0.984	0.016
K80.3 Calculus of bile duct with cholangitis	0.000	0.984	0.016
K50.0 Crohn's disease of small intestine	0.016	0.984	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.984	0.016
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.000	0.984	0.016
T45.0 Antiallergic and antiemetic drugs	0.000	0.985	0.015
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.985	0.015
K50 Crohn's disease [regional enteritis]	0.014	0.986	0.000
T45.2 Vitamins, not elsewhere classified	0.000	0.986	0.014
K50.1 Crohn's disease of large intestine	0.013	0.986	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.987	0.013
T45.5 Anticoagulants	0.000	0.987	0.013
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.987	0.013
K50.8 Other Crohn's disease	0.013	0.987	0.000
T45.4 Iron and its compounds	0.000	0.988	0.012
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.988	0.012
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.988	0.012
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction	0.000	0.988	0.012
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.988	0.012
K50.9 Crohn's disease, unspecified	0.012	0.988	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.988	0.011
T45.8 Other primarily systemic and haematological agents	0.000	0.988	0.011
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.988	0.011
T45.6 Fibrinolysis-affecting drugs	0.000	0.988	0.011
T45.3 Enzymes, not elsewhere classified	0.000	0.988	0.011
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.989	0.011
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.989	0.011
E89.0 Postprocedural hypothyroidism	0.011	0.989	0.000
K80.2 Calculus of gallbladder without cholecystitis	0.000	0.989	0.011
Z99.2 Dependence on renal dialysis	0.000	0.989	0.011
T43.9 Psychotropic drug, unspecified	0.000	0.989	0.011
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.989	0.010
K80.8 Other cholelithiasis	0.000	0.990	0.010
T36 Poisoning by systemic antibiotics	0.000	0.990	0.010
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.990	0.010
T46.1 Calcium-channel blockers	0.000	0.990	0.010
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.990	0.010
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.990	0.010
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.990	0.010
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.990	0.010
M21.1 Varus deformity, not elsewhere classified	0.000	0.990	0.010
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.990	0.009
T50.1 Loop [high-ceiling] diuretics	0.000	0.990	0.009
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.990	0.009
C01 Malignant neoplasm of base of tongue	0.000	0.990	0.009
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.991	0.009
T43.6 Psychostimulants with abuse potential	0.000	0.991	0.009
Z49.1 Extracorporeal dialysis	0.000	0.991	0.009
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.991	0.009
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.991	0.009
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.991	0.009
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.991	0.009
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.991	0.009
T50.7 Analeptics and opioid receptor antagonists	0.000	0.991	0.009
T50.5 Appetite depressants	0.000	0.991	0.009
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.991	0.009
T50.0 Mineralocorticoids and their antagonists	0.000	0.991	0.009
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.991	0.009
T46.7 Peripheral vasodilators	0.000	0.991	0.009
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.991	0.009
E04 Other non-toxic goitre	0.009	0.991	0.000
T50.4 Drugs affecting uric acid metabolism	0.000	0.991	0.008
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.992	0.008
E04.2 Non-toxic multinodular goitre	0.008	0.992	0.000
T36.0 Penicillins	0.000	0.992	0.008
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.992	0.008
M20.1 Hallux valgus (acquired)	0.008	0.992	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.992	0.008
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.992	0.008
T50.8 Diagnostic agents	0.000	0.992	0.008
T36.4 Tetracyclines	0.000	0.992	0.008
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.992	0.008
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.000	0.992	0.008
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.000	0.992	0.008
T36.3 Macrolides	0.000	0.992	0.008
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.992	0.008
T48.5 Anti-common-cold drugs	0.000	0.992	0.008
T43.2 Other and unspecified antidepressants	0.000	0.992	0.008
T36.9 Systemic antibiotic, unspecified	0.000	0.992	0.007
T36.7 Antifungal antibiotics, systemically used	0.000	0.992	0.007
T36.6 Rifamycins	0.000	0.992	0.007
T36.5 Aminoglycosides	0.000	0.992	0.007
T36.2 Chloramphenicol group	0.000	0.992	0.007
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.992	0.007
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.992	0.008
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.992	0.008
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.992	0.007
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.992	0.007
T48.4 Expectorants	0.000	0.992	0.007
T48.3 Antitussives	0.000	0.992	0.007
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.992	0.007
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.992	0.007
T48.0 Oxytocic drugs	0.000	0.992	0.007
T49.9 Topical agent, unspecified	0.000	0.992	0.007
T49.8 Other topical agents	0.000	0.992	0.007
T49.7 Dental drugs, topically applied	0.000	0.992	0.007
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.992	0.007
T49.5 Ophthalmological drugs and preparations	0.000	0.992	0.007
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.992	0.007
T49.3 Emollients, demulcents and protectants	0.000	0.992	0.007
T49.2 Local astringents and local detergents	0.000	0.992	0.007
T49.1 Antipruritics	0.000	0.992	0.007
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.000	0.993	0.007
M21.18 Varus deformity, not elsewhere classified (Other)	0.000	0.993	0.007
M21.14 Varus deformity, not elsewhere classified (Hand)	0.000	0.993	0.007
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.000	0.993	0.007
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.000	0.993	0.007
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.000	0.993	0.007
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.000	0.993	0.007
T36.8 Other systemic antibiotics	0.000	0.993	0.007
T41.2 Other and unspecified general anaesthetics	0.000	0.993	0.007
T41.5 Therapeutic gases	0.000	0.993	0.007
T41.4 Anaesthetic, unspecified	0.000	0.993	0.007
T41.3 Local anaesthetics	0.000	0.993	0.007
T41.1 Intravenous anaesthetics	0.000	0.993	0.007
T41.0 Inhaled anaesthetics	0.000	0.993	0.007
N18.0 End-stage renal disease	0.000	0.993	0.007
T40.4 Other synthetic narcotics	0.000	0.993	0.007
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.993	0.007
T38.0 Glucocorticoids and synthetic analogues	0.000	0.993	0.007
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.993	0.007
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.993	0.007
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.993	0.007
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.993	0.007
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.993	0.007
T44.0 Anticholinesterase agents	0.000	0.993	0.007
T38.5 Other oestrogens and progestogens	0.000	0.993	0.007
T38.9 Other and unspecified hormone antagonists	0.000	0.993	0.007
T38.7 Androgens and anabolic congeners	0.000	0.993	0.007
T38.4 Oral contraceptives	0.000	0.993	0.007
T38.2 Antithyroid drugs	0.000	0.993	0.007
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.993	0.006
T37.5 Antiviral drugs	0.000	0.993	0.006
T37.4 Anthelminthics	0.000	0.993	0.006
T37.3 Other antiprotozoal drugs	0.000	0.993	0.006
T37.1 Antimycobacterial drugs	0.000	0.993	0.006
T37.0 Sulphonamides	0.000	0.993	0.006
T40.6 Other and unspecified narcotics	0.000	0.993	0.007
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.993	0.007
T38.1 Thyroid hormones and substitutes	0.000	0.993	0.007
T47.2 Stimulant laxatives	0.000	0.993	0.007
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.993	0.006
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.993	0.006
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.993	0.006
T47.7 Emetics	0.000	0.993	0.006
T47.5 Digestants	0.000	0.993	0.006
T47.3 Saline and osmotic laxatives	0.000	0.993	0.006
T47.4 Other laxatives	0.000	0.994	0.006
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.994	0.006
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.994	0.006
E04.8 Other specified non-toxic goitre	0.006	0.994	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.994	0.006
T47.6 Antidiarrhoeal drugs	0.000	0.994	0.006
T47.0 Histamine H(2)-receptor antagonists	0.000	0.994	0.006
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.994	0.006
T40.8 Lysergide [LSD]	0.000	0.994	0.006
T40.7 Cannabis (derivatives)	0.000	0.994	0.006
T40.0 Opium	0.000	0.994	0.006
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.000	0.994	0.006
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.994	0.006
R56.8 Other and unspecified convulsions	0.000	0.994	0.006
T40.1 Heroin	0.000	0.994	0.006
E04.0 Non-toxic diffuse goitre	0.006	0.994	0.000
N18.9 Chronic renal failure, unspecified	0.000	0.994	0.006
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.994	0.006
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.994	0.006
N18 Chronic renal failure	0.000	0.994	0.006
T40.3 Methadone	0.000	0.994	0.006
N18.2 Chronic kidney disease, stage 2	0.000	0.994	0.006
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.994	0.006
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.994	0.006
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.994	0.006
T40.5 Cocaine	0.000	0.994	0.006
M21 Other acquired deformities of limbs	0.000	0.994	0.006
U80.1 Methicillin resistant agent	0.006	0.994	0.000
C79.9 Secondary malignant neoplasm, unspecified site	0.000	0.994	0.006
N18.5 Chronic kidney disease, stage 5	0.000	0.994	0.005
N18.1 Chronic kidney disease, stage 1	0.000	0.995	0.005
K82.8 Other specified diseases of gallbladder	0.000	0.995	0.005
R50.9 Fever, unspecified	0.000	0.995	0.005
R07.0 Pain in throat	0.000	0.995	0.005
K82 Other diseases of gallbladder	0.000	0.995	0.005
T39.4 Antirheumatics, not elsewhere classified	0.000	0.995	0.005
T39.2 Pyrazolone derivatives	0.000	0.995	0.005
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.995	0.005
M20.3 Other deformity of hallux (acquired)	0.005	0.995	0.000
M21.4 Flat foot [pes planus] (acquired)	0.000	0.995	0.005
O36.6 Maternal care for excessive foetal growth	0.005	0.995	0.000
M21.8 Other specified acquired deformities of limbs	0.000	0.995	0.005
M21.9 Acquired deformity of limb, unspecified	0.000	0.995	0.005
M21.0 Valgus deformity, not elsewhere classified	0.000	0.995	0.005
Z49 Care involving dialysis	0.000	0.995	0.005
K82.1 Hydrops of gallbladder	0.000	0.995	0.005
N18.8 Other chronic renal failure	0.000	0.995	0.005
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.000	0.995	0.005
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.000	0.995	0.005
M21.6 Other acquired deformities of ankle and foot	0.000	0.995	0.004
Z92.6 Personal history of chemotherapy for neoplastic disease	0.000	0.995	0.005
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.000	0.995	0.005
K82.4 Cholesterolosis of gallbladder	0.000	0.995	0.004
Z43.3 Attention to colostomy	0.004	0.995	0.000
U80 Agent resistant to penicillin and related antibiotics	0.004	0.996	0.000
T39.0 Salicylates	0.000	0.996	0.004
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.000	0.996	0.004
K82.9 Disease of gallbladder, unspecified	0.000	0.996	0.004
M81.90 Osteoporosis, unspecified (Multiple sites)	0.004	0.996	0.000
M21.2 Flexion deformity	0.000	0.996	0.004
T42.0 Hydantoin derivatives	0.000	0.996	0.004
Z49.2 Other dialysis	0.000	0.996	0.004
T40.2 Other opioids	0.000	0.996	0.004
M20 Acquired deformities of fingers and toes	0.004	0.996	0.000
M21.94 Acquired deformity of limb, unspecified (Hand)	0.000	0.996	0.004
H83.0 Labyrinthitis	0.004	0.996	0.000
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.000	0.996	0.004
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.000	0.996	0.004
M21.3 Wrist or foot drop (acquired)	0.000	0.996	0.004
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.000	0.996	0.004
Z99.1 Dependence on respirator	0.000	0.996	0.004
M21.26 Flexion deformity (Lower leg)	0.000	0.996	0.004
I42.0 Dilated cardiomyopathy	0.000	0.996	0.004
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.996	0.004
M21.96 Acquired deformity of limb, unspecified (Lower leg)	0.000	0.996	0.004
M21.87 Other specified acquired deformities of limbs (Ankle and foot)	0.000	0.996	0.004
E11 Non-insulin-dependent diabetes mellitus	0.000	0.996	0.004
K82.0 Obstruction of gallbladder	0.000	0.996	0.004
U80.8 Agent resistant to other penicillin-related antibiotic	0.004	0.996	0.000
O36 Maternal care for other known or suspected foetal problems	0.004	0.996	0.000
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.000	0.996	0.004
M21.48 Flat foot [pes planus] (acquired)-Other	0.000	0.996	0.004
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.000	0.996	0.004
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.000	0.996	0.004
M21.44 Flat foot [pes planus] (acquired)-Hand	0.000	0.996	0.004
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.000	0.996	0.004
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.000	0.996	0.004
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.000	0.996	0.004
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.000	0.996	0.004
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.996	0.004
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.996	0.004
T42.3 Barbiturates	0.000	0.996	0.004
T42.2 Succinimides and oxazolidinediones	0.000	0.996	0.004
K83.9 Disease of biliary tract, unspecified	0.000	0.996	0.004
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.000	0.996	0.004
M21.88 Other specified acquired deformities of limbs-Other	0.000	0.996	0.004
M21.84 Other specified acquired deformities of limbs (Hand)	0.000	0.996	0.004
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.000	0.996	0.004
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.000	0.996	0.004
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.000	0.996	0.004
M21.99 Acquired deformity of limb, unspecified (Site unspecified)	0.000	0.996	0.004
M21.98 Acquired deformity of limb, unspecified-Other	0.000	0.996	0.004
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)	0.000	0.996	0.004
M21.95 Acquired deformity of limb, unspecified (Pelvic region and thigh)	0.000	0.996	0.004
M21.93 Acquired deformity of limb, unspecified (Forearm)	0.000	0.996	0.004
M21.92 Acquired deformity of limb, unspecified (Upper arm)	0.000	0.996	0.004
M21.91 Acquired deformity of limb, unspecified (Shoulder region)	0.000	0.996	0.004
M21.90 Acquired deformity of limb, unspecified (Multiple sites)	0.000	0.996	0.004
K83 Other diseases of biliary tract	0.000	0.996	0.004
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.000	0.996	0.004
M21.08 Valgus deformity, not elsewhere classified (Other)	0.000	0.996	0.004
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.000	0.996	0.004
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.000	0.996	0.004
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.000	0.996	0.004
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.000	0.996	0.004
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.000	0.996	0.004
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.000	0.996	0.004
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.000	0.996	0.004
R50.8 Other specified fever	0.000	0.996	0.004
M21.7 Unequal limb length (acquired)	0.000	0.996	0.003
M21.83 Other specified acquired deformities of limbs (Forearm)	0.000	0.996	0.003
K82.3 Fistula of gallbladder	0.000	0.996	0.003
S06.00 Concussion (without open intracranial wound)	0.000	0.996	0.004
Z99.0 Dependence on aspirator	0.000	0.996	0.003
M20.6 Acquired deformity of toe(s), unspecified	0.004	0.996	0.000
Z99.4 Dependence on artificial heart	0.000	0.996	0.003
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.000	0.996	0.003
M21.68 Other acquired deformities of ankle and foot-Other	0.000	0.996	0.003
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.000	0.996	0.003
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.000	0.996	0.003
M21.64 Other acquired deformities of ankle and foot-Hand	0.000	0.996	0.003
M21.63 Other acquired deformities of ankle and foot-Forearm	0.000	0.996	0.003
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.000	0.996	0.003
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.000	0.996	0.003
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.000	0.996	0.003
Z49.0 Preparatory care for dialysis	0.000	0.996	0.003
D26.0 Cervix uteri	0.000	0.996	0.004
T42.1 Iminostilbenes	0.000	0.996	0.003
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.003	0.996	0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.000	0.996	0.003
O36.1 Maternal care for other isoimmunisation	0.003	0.997	0.000
R50 Fever of unknown origin	0.000	0.997	0.003
M21.22 Flexion deformity (Upper arm)	0.000	0.997	0.003
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.997	0.003
U80.0 Penicillin resistant agent	0.003	0.997	0.000
Z99.9 Dependence on unspecified enabling machine and device	0.000	0.997	0.003
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.000	0.997	0.003
M21.23 Flexion deformity (Forearm)	0.000	0.997	0.003
K82.2 Perforation of gallbladder	0.000	0.997	0.003
K83.1 Obstruction of bile duct	0.000	0.997	0.003
O36.4 Maternal care for intra-uterine death	0.003	0.997	0.000
M21.29 Flexion deformity (Site unspecified)	0.000	0.997	0.003
M21.28 Flexion deformity (Other)	0.000	0.997	0.003
M21.21 Flexion deformity (Shoulder region)	0.000	0.997	0.003
O36.3 Maternal care for signs of foetal hypoxia	0.003	0.997	0.000
M20.4 Other hammer toe(s) (acquired)	0.003	0.997	0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.003	0.997	0.000
Z99.8 Dependence on other enabling machines and devices	0.000	0.997	0.003
E11.6 With other specified complications	0.000	0.997	0.003
M21.20 Flexion deformity (Multiple sites)	0.000	0.997	0.003
M21.39 Wrist or foot drop (acquired)-Site unspec	0.000	0.997	0.003
M21.38 Wrist or foot drop (acquired)-Other	0.000	0.997	0.003
M21.36 Wrist or foot drop (acquired)-Lower leg	0.000	0.997	0.003
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.000	0.997	0.003
M21.34 Wrist or foot drop (acquired) (Hand)	0.000	0.997	0.003
M21.32 Wrist or foot drop (acquired)-Upper arm	0.000	0.997	0.003
M21.31 Wrist or foot drop (acquired)-Shldr region	0.000	0.997	0.003
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.000	0.997	0.003
E11.2 With renal complications	0.000	0.997	0.003
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.000	0.997	0.003
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.000	0.997	0.003
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.000	0.997	0.003
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.000	0.997	0.003
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.000	0.997	0.003
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar	0.000	0.997	0.003
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re	0.000	0.997	0.003
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)	0.000	0.997	0.003
E11.7 With multiple complications	0.000	0.997	0.003
N71.1 Chronic inflammatory disease of uterus	0.000	0.997	0.003
M21.33 Wrist or foot drop (acquired) (Forearm)	0.000	0.997	0.003
O36.5 Maternal care for poor foetal growth	0.003	0.997	0.000
U51.0 Not Previously admitted to a psyciatric hospital	0.003	0.997	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.003	0.997	0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.000	0.997	0.003
S06.0 Concussion	0.000	0.997	0.003
E89.4 Postprocedural ovarian failure	0.003	0.997	0.000
R50.2 Drug-induced fever	0.000	0.997	0.003
S00.8 Superficial injury of other parts of head	0.003	0.997	0.000
Z99.3 Dependence on wheelchair	0.000	0.997	0.003
E46 Unspecified protein-energy malnutrition	0.000	0.997	0.003
O36.9 Maternal care for foetal problem, unspecified	0.003	0.997	0.000
O36.2 Maternal care for hydrops foetalis	0.003	0.997	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.000	0.997	0.003
R50.1 Persistent fever	0.000	0.997	0.003
M21.27 Flexion deformity (Ankle and foot)	0.000	0.997	0.003
R56 Convulsions, not elsewhere classified	0.000	0.997	0.003
M21.79 Unequal limb length (acquired) (Site unspecified)	0.000	0.997	0.003
M21.78 Unequal limb length (acquired)-Other	0.000	0.997	0.003
M21.77 Unequal limb length (acquired) (Ankle and foot)	0.000	0.997	0.003
M21.74 Unequal limb length (acquired) (Hand)	0.000	0.997	0.003
M21.72 Unequal limb length (acquired) (Upper arm)	0.000	0.997	0.003
M21.71 Unequal limb length (acquired)-Shldr region	0.000	0.997	0.003
M21.70 Unequal limb length (acquired) (Multiple sites)	0.000	0.997	0.003
E89.3 Postprocedural hypopituitarism	0.003	0.997	0.000
K83.3 Fistula of bile duct	0.000	0.997	0.003
O36.8 Maternal care for other specified foetal problems	0.003	0.997	0.000
M21.24 Flexion deformity (Hand)	0.000	0.997	0.003
U51 Admission status on psychiatric patients	0.003	0.997	0.000
M21.25 Flexion deformity (Pelvic region and thigh)	0.000	0.997	0.003
E11.1 With ketoacidosis	0.000	0.997	0.003
K83.2 Perforation of bile duct	0.000	0.997	0.003
I25.5 Ischaemic cardiomyopathy	0.003	0.997	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.000	0.997	0.003
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.000	0.997	0.003
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.003	0.997	0.000
K87.1 Disorders of pancreas in diseases classified elsewhere	0.000	0.997	0.003
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere	0.000	0.997	0.003
E89.5 Postprocedural testicular hypofunction	0.003	0.997	0.000
E89.1 Postprocedural hypoinsulinaemia	0.003	0.997	0.000
K83.5 Biliary cyst	0.000	0.997	0.003
E11.8 With unspecified complications	0.000	0.997	0.003
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)	0.000	0.997	0.002
M21.73 Unequal limb length (acquired) (Forearm)	0.000	0.997	0.002
D37.4 Colon	0.000	0.997	0.003
E89.8 Other postprocedural endocrine and metabolic disorders	0.003	0.997	0.000
N81.5 Vaginal enterocele	0.000	0.997	0.003
M21.76 Unequal limb length (acquired) (Lower leg)	0.000	0.997	0.002
K83.0 Cholangitis	0.000	0.997	0.003
S06.80 Other intracranial injuries (without open intracranial wound)	0.000	0.997	0.003
O87.2 Haemorrhoids in the puerperium	0.000	0.997	0.003
E11.5 With peripheral circulatory complications	0.000	0.997	0.003
S06.9 Intracranial injury, unspecified	0.000	0.997	0.003
D36.1 Peripheral nerves and autonomic nervous system	0.003	0.997	0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.003	0.997	0.000
J95.0 Tracheostomy malfunction	0.000	0.997	0.003
K83.4 Spasm of sphincter of Oddi	0.000	0.997	0.002
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.997	0.003
S06.8 Other intracranial injuries	0.000	0.997	0.003
E11.0 With coma	0.000	0.997	0.002
S06 Intracranial injury	0.000	0.997	0.003
H02.0 Entropion and trichiasis of eyelid	0.000	0.997	0.003
M20.0 Deformity of finger(s)	0.002	0.997	0.000
K65.9 Peritonitis, unspecified	0.000	0.997	0.003
M20.5 Other deformities of toe(s) (acquired)	0.003	0.997	0.000
R60.9 Oedema, unspecified	0.000	0.997	0.003
C79 Secondary malignant neoplasm of other sites	0.000	0.997	0.002
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.000	0.998	0.002
E11.3 With ophthalmic complications	0.000	0.998	0.002
U50 Level of care administered to neonates	0.002	0.998	0.000
U07 Emergency use of U07	0.002	0.998	0.000
U06 Emergency use of U06	0.002	0.998	0.000
U04 Severe acute respiratory syndrome [SARS]	0.002	0.998	0.000
U52 First in a series of a regular day/night admissions	0.002	0.998	0.000
S06.01 Concussion (with open intracranial wound)	0.000	0.998	0.002
K55.2 Angiodysplasia of colon	0.002	0.998	0.000
N18.4 Chronic kidney disease, stage 4	0.000	0.998	0.002
H83 Other diseases of inner ear	0.002	0.998	0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.000	0.998	0.002
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.002	0.998	0.000
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
H81.0 Meniere's disease	0.002	0.998	0.000
O34.4 Maternal care for other abnormalities of cervix	0.002	0.998	0.000
S06.1 Traumatic cerebral oedema	0.000	0.998	0.002
O34 Maternal care for known or suspected abnormality of pelvic organs	0.002	0.998	0.000
E89.2 Postprocedural hypoparathyroidism	0.002	0.998	0.000
R56.0 Febrile convulsions	0.000	0.998	0.002
U81 Agent resistant to vancomycin and related antibiotics	0.002	0.998	0.000
M89.87 Other specified disorders of bone (Ankle and foot)	0.000	0.998	0.002
U51.2 Previously admitted to a psychiatric hospital of another provider	0.002	0.998	0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.000	0.998	0.002
K83.8 Other specified diseases of biliary tract	0.000	0.998	0.002
M75.0 Adhesive capsulitis of shoulder	0.000	0.998	0.002
O34.8 Maternal care for other abnormalities of pelvic organs	0.002	0.998	0.000
E11.4 With neurological complications	0.000	0.998	0.002
S06.4 Epidural haemorrhage	0.000	0.998	0.002
K65.0 Acute peritonitis	0.000	0.998	0.002
O34.2 Maternal care due to uterine scar from previous surgery	0.002	0.998	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.002	0.998	0.000
K85 Acute pancreatitis	0.000	0.998	0.002
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.000	0.998	0.002
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.000	0.998	0.002
M89.8 Other specified disorders of bone	0.000	0.998	0.002
M89.89 Other specified disorders of bone (Site unspecified)	0.000	0.998	0.002
M89.83 Other specified disorders of bone (Forearm)	0.000	0.998	0.002
U51.1 Previously admitted to a psychiatric hospital of the provider	0.002	0.998	0.000
S06.81 Other intracranial injuries (with open intracranial wound)	0.000	0.998	0.002
I25.1 Atherosclerotic heart disease	0.002	0.998	0.000
O34.3 Maternal care for cervical incompetence	0.002	0.998	0.000
Y86 Sequelae of other accidents	0.000	0.998	0.002
M89.86 Other specified disorders of bone (Lower leg)	0.000	0.998	0.002
S06.7 Intracranial injury with prolonged coma	0.000	0.998	0.002
S06.2 Diffuse brain injury	0.000	0.998	0.002
H83.2 Labyrinthine dysfunction	0.002	0.998	0.000
U04.9 Severe acute respiratory syndrome [SARS], unspecified	0.002	0.998	0.000
U06.9 Emergency use of U06.9	0.002	0.998	0.000
U06.8 Emergency use of U06.8	0.002	0.998	0.000
U06.7 Emergency use of U06.7	0.002	0.998	0.000
U06.6 Emergency use of U06.6	0.002	0.998	0.000
U06.5 Emergency use of U06.5	0.002	0.998	0.000
U06.4 Emergency use of U06.4	0.002	0.998	0.000
U06.3 Emergency use of U06.3	0.002	0.998	0.000
U06.2 Emergency use of U06.2	0.002	0.998	0.000
U06.1 Emergency use of U06.1	0.002	0.998	0.000
U06.0 Emergency use of U06.0	0.002	0.998	0.000
U07.9 Emergency use of U07.9	0.002	0.998	0.000
U07.8 Emergency use of U07.8	0.002	0.998	0.000
U07.7 Emergency use of U07.7	0.002	0.998	0.000
U07.6 Emergency use of U07.6	0.002	0.998	0.000
U07.5 Emergency use of U07.5	0.002	0.998	0.000
U07.4 Emergency use of U07.4	0.002	0.998	0.000
U07.3 Emergency use of U07.3	0.002	0.998	0.000
U07.2 Emergency use of U07.2	0.002	0.998	0.000
U07.1 Emergency use of U07.1	0.002	0.998	0.000
U07.0 Emergency use of U07.0	0.002	0.998	0.000
U50.9 Inquest Adjourned Death	0.002	0.998	0.000
U50.3 Level of care administered to neonates (Maximal Intensive Care)	0.002	0.998	0.000
U50.2 Level of care administered to neonates (High Dependancy Intensive Care)	0.002	0.998	0.000
U50.1 Level of care administered to neonates (Special Care)	0.002	0.998	0.000
U50.0 Level of care administered to neonates (Normal Care)	0.002	0.998	0.000
S06.3 Focal brain injury	0.000	0.998	0.002
D26 Other benign neoplasms of uterus	0.000	0.998	0.002
O34.5 Maternal care for other abnormalities of gravid uterus	0.002	0.998	0.000
N64.5 Other signs and symptoms in breast	0.000	0.998	0.002
N71 Inflammatory disease of uterus, except cervix	0.000	0.998	0.002
H83.1 Labyrinthine fistula	0.002	0.998	0.000
O34.0 Maternal care for congenital malformation of uterus	0.002	0.998	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.000	0.998	0.002
G31.2 Degeneration of nervous system due to alcohol	0.000	0.998	0.002
H83.9 Disease of inner ear, unspecified	0.002	0.998	0.000
K61.0 Anal abscess	0.000	0.998	0.002
S06.5 Traumatic subdural haemorrhage	0.000	0.998	0.002
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.000	0.998	0.002
D26.9 Uterus, unspecified	0.000	0.998	0.002
I42.7 Cardiomyopathy due to drugs and other external agents	0.000	0.998	0.002
N64.4 Mastodynia	0.000	0.998	0.002
Z73.9 Problem related to life-management difficulty, unspecified	0.000	0.998	0.002
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere	0.000	0.998	0.002
C79.2 Secondary malignant neoplasm of skin	0.000	0.998	0.002
E04.9 Non-toxic goitre, unspecified	0.002	0.998	0.000
I42 Cardiomyopathy	0.000	0.998	0.002
O34.6 Maternal care for abnormality of vagina	0.002	0.998	0.000
H83.8 Other specified diseases of inner ear	0.002	0.998	0.000
H83.3 Noise effects on inner ear	0.002	0.998	0.000
J95.8 Other postprocedural respiratory disorders	0.000	0.998	0.002
K85.0 Idiopathic acute pancreatitis	0.000	0.998	0.002
M31.3 Wegener's granulomatosis	0.000	0.998	0.002
T82.0 Mechanical complication of heart valve prosthesis	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations