TreeWAS – Variant ID: rs7195386

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
R27.0 Ataxia, unspecified	0.062	0.938	0.000
R27 Other lack of coordination	0.061	0.939	0.000
R27.8 Other and unspecified lack of coordination	0.060	0.940	0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.050	0.950	0.000
R26 Abnormalities of gait and mobility	0.047	0.953	0.000
R25 Abnormal involuntary movements	0.046	0.954	0.000
R25.2 Cramp and spasm	0.043	0.957	0.000
R26.0 Ataxic gait	0.043	0.957	0.000
Y45.0 Opioids and related analgesics	0.042	0.958	0.000
R26.2 Difficulty in walking, not elsewhere classified	0.041	0.959	0.000
Y43 Primarily systemic agents	0.040	0.960	0.000
R25.3 Fasciculation	0.038	0.962	0.000
Y43.1 Antineoplastic antimetabolites	0.038	0.962	0.000
Y43.4 Immunosuppressive agents	0.038	0.962	0.000
Y43.0 Antiallergic and antiemetic drugs	0.036	0.964	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.036	0.964	0.000
Y43.3 Other antineoplastic drugs	0.035	0.965	0.000
Y45.2 Propionic acid derivatives	0.035	0.965	0.000
R25.1 Tremor, unspecified	0.035	0.965	0.000
R26.1 Paralytic gait	0.034	0.966	0.000
R26.3 Immobility	0.034	0.966	0.000
R25.0 Abnormal head movements	0.033	0.967	0.000
I84.4 External haemorrhoids with other complications	0.033	0.967	0.000
Y45.5 4-Aminophenol derivatives	0.031	0.969	0.000
Y43.2 Antineoplastic natural products	0.031	0.969	0.000
R26.8 Other and unspecified abnormalities of gait and mobility	0.030	0.970	0.000
Y43.9 Primarily systemic agent, unspecified	0.029	0.971	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.029	0.971	0.000
Y43.6 Enzymes, not elsewhere classified	0.029	0.971	0.000
Y43.5 Acidifying and alkalising agents	0.029	0.971	0.000
Y45.4 Antirheumatics	0.025	0.975	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.025	0.975	0.000
R25.8 Other and unspecified abnormal involuntary movements	0.025	0.975	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.022	0.977	0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.021	0.979	0.000
Y45.8 Other analgesics and antipyretics	0.021	0.979	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.020	0.980	0.000
Y45.1 Salicylates	0.020	0.980	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.020	0.980	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.020	0.980	0.000
Y57 Other and unspecified drugs and medicaments	0.019	0.981	0.000
S43.0 Dislocation of shoulder joint	0.019	0.981	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.019	0.981	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.019	0.981	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.018	0.982	0.000
Z60.2 Living alone	0.000	0.982	0.018
R29.6 Tendency to fall, not elsewhere classified	0.018	0.982	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.017	0.983	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.017	0.983	0.000
Y59 Other and unspecified vaccines and biological substances	0.017	0.983	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.017	0.983	0.000
Y57.5 X-ray contrast media	0.017	0.983	0.000
Y58 Bacterial vaccines	0.017	0.983	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.016	0.983	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.017	0.983	0.000
Y42.4 Oral contraceptives	0.016	0.984	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.016	0.984	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.016	0.984	0.000
Y53.4 Other laxatives	0.016	0.984	0.000
R29.2 Abnormal reflex	0.016	0.984	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.016	0.984	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.016	0.984	0.000
Y53.2 Stimulant laxatives	0.016	0.984	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.016	0.984	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.016	0.984	0.000
R29.4 Clicking hip	0.015	0.984	0.000
R29.3 Abnormal posture	0.015	0.984	0.000
Y53.3 Saline and osmotic laxatives	0.015	0.985	0.000
Y57.6 Other diagnostic agents	0.015	0.985	0.000
Y41.5 Antiviral drugs	0.015	0.985	0.000
Y49.2 Other and unspecified antidepressants	0.015	0.985	0.000
Y49.9 Psychotropic drug, unspecified	0.015	0.985	0.000
Y49.7 Psychostimulants with abuse potential	0.015	0.985	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.015	0.985	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.015	0.985	0.000
Y42.9 Other and unspecified hormone antagonists	0.015	0.985	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.014	0.985	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.014	0.985	0.000
H53.0 Amblyopia ex anopsia	0.015	0.985	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.014	0.986	0.000
Y53.7 Emetics	0.014	0.986	0.000
Y53.6 Antidiarrhoeal drugs	0.014	0.986	0.000
Y53.5 Digestants	0.014	0.986	0.000
Y53.0 Histamine H2-receptor antagonists	0.014	0.986	0.000
Y41.1 Antimycobacterial drugs	0.014	0.986	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.014	0.986	0.000
Y57.7 Vitamins, not elsewhere classified	0.014	0.986	0.000
Y57.4 Pharmaceutical excipients	0.014	0.986	0.000
Y57.3 Alcohol deterrents	0.014	0.986	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.014	0.986	0.000
Y57.1 Lipotropic drugs	0.014	0.986	0.000
Y57.0 Appetite depressants [anorectics]	0.014	0.986	0.000
Y42.2 Antithyroid drugs	0.014	0.986	0.000
Y41.0 Sulphonamides	0.014	0.986	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.014	0.986	0.000
Y50.9 Central nervous system stimulant, unspecified	0.014	0.986	0.000
Y50.8 Other central nervous system stimulants	0.014	0.986	0.000
Y50.1 Opioid receptor antagonists	0.014	0.986	0.000
Y50.0 Analeptics	0.014	0.986	0.000
Y48 Anaesthetics and therapeutic gases	0.014	0.986	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.014	0.986	0.000
Y41.4 Anthelminthics	0.014	0.986	0.000
Y41.3 Other antiprotozoal drugs	0.014	0.986	0.000
Y46.6 Other and unspecified antiepileptics	0.014	0.986	0.000
R29.1 Meningismus	0.013	0.986	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.013	0.986	0.000
Y42.1 Thyroid hormones and substitutes	0.013	0.987	0.000
Y57.9 Drug or medicament, unspecified	0.013	0.987	0.000
Y56.3 Emollients, demulcents and protectants	0.013	0.987	0.000
Y56.9 Topical agent, unspecified	0.012	0.987	0.000
Y56.8 Other topical agents	0.012	0.987	0.000
Y56.7 Dental drugs, topically applied	0.012	0.987	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.012	0.987	0.000
Y56.5 Ophthalmological drugs and preparations	0.012	0.987	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.012	0.987	0.000
Y56.2 Local astringents and local detergents	0.012	0.987	0.000
Y56.1 Antipruritics	0.012	0.987	0.000
R29.0 Tetany	0.012	0.987	0.000
Y59.9 Vaccine or biological substance, unspecified	0.012	0.987	0.000
Y59.8 Other specified vaccines and biological substances	0.012	0.987	0.000
Y59.2 Protozoal vaccines	0.012	0.987	0.000
Y59.1 Rickettsial vaccines	0.012	0.987	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.012	0.987	0.000
Y59.3 Immunoglobulin	0.012	0.987	0.000
Y42.7 Androgens and anabolic congeners	0.012	0.988	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.012	0.988	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.012	0.988	0.000
Y58.9 Other and unspecified bacterial vaccines	0.012	0.988	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.012	0.988	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.012	0.988	0.000
Y58.5 Diphtheria vaccine	0.012	0.988	0.000
Y58.4 Tetanus vaccine	0.012	0.988	0.000
Y58.3 Plague vaccine	0.012	0.988	0.000
Y58.2 Cholera vaccine	0.012	0.988	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.012	0.988	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.012	0.988	0.000
Y55.5 Anticommon cold drugs	0.012	0.988	0.000
Y55.3 Antitussives	0.012	0.988	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.012	0.988	0.000
Y55.0 Oxytocic drugs	0.012	0.988	0.000
S64.4 Injury of digital nerve of other finger	0.012	0.988	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.012	0.988	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.012	0.988	0.000
Y55.4 Expectorants	0.012	0.988	0.000
Y59.0 Viral vaccines	0.012	0.988	0.000
Y46.8 Antispasticity drugs	0.012	0.988	0.000
Y46.3 Deoxybarbiturates	0.012	0.988	0.000
Y46.1 Oxazolidinediones	0.012	0.988	0.000
Y46.0 Succinimides	0.012	0.988	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.012	0.988	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.012	0.988	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.012	0.988	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.012	0.988	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.012	0.988	0.000
Y51.0 Anticholinesterase agents	0.012	0.988	0.000
Y40 Systemic antibiotics	0.012	0.988	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.011	0.988	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.011	0.988	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.011	0.988	0.000
Y47.4 Bromine compounds	0.011	0.988	0.000
Y47.3 Paraldehyde	0.011	0.988	0.000
Y47.2 Chloral derivatives	0.011	0.988	0.000
Y47.0 Barbiturates, not elsewhere classified	0.011	0.988	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.011	0.988	0.000
Y46.5 Valproic acid	0.011	0.988	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.011	0.989	0.000
F33.9 Recurrent depressive disorder, unspecified	0.011	0.989	0.000
Y49.5 Other antipsychotics and neuroleptics	0.011	0.989	0.000
K90.9 Intestinal malabsorption, unspecified	0.000	0.989	0.011
M79.54 Residual foreign body in soft tissue (Hand)	0.000	0.989	0.011
Y46.7 Anti-Parkinsonism drugs	0.011	0.989	0.000
Y46.2 Hydantoin derivatives	0.011	0.989	0.000
Y58.0 BCG vaccine	0.011	0.989	0.000
O16 Unspecified maternal hypertension	0.000	0.989	0.011
Y57.8 Other drugs and medicaments	0.010	0.990	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.010	0.990	0.000
Y48.5 Therapeutic gases	0.010	0.990	0.000
Y48.1 Parenteral anaesthetics	0.010	0.990	0.000
Y48.0 Inhaled anaesthetics	0.010	0.990	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.010	0.990	0.000
F33 Recurrent depressive disorder	0.010	0.990	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.010	0.990	0.000
Y40.8 Other systemic antibiotics	0.010	0.990	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.010	0.990	0.000
Y52 Agents primarily affecting the cardiovascular system	0.010	0.990	0.000
Y48.4 Anaesthetic, unspecified	0.010	0.990	0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.010	0.990	0.000
Y54.8 Agents affecting uric acid metabolism	0.009	0.991	0.000
Y47.1 Benzodiazepines	0.009	0.991	0.000
Y40.5 Aminoglycosides	0.009	0.991	0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.991	0.009
Y54.9 Mineral salts, not elsewhere classified	0.009	0.991	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.009	0.991	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.009	0.991	0.000
Y54.0 Mineralocorticoids	0.009	0.991	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.009	0.991	0.000
Y46.4 Iminostilbenes	0.008	0.991	0.000
Y54.3 Benzothiadiazine derivatives	0.009	0.991	0.000
Y48.2 Other and unspecified general anaesthetics	0.008	0.991	0.000
Y40.2 Chloramphenicol group	0.009	0.991	0.000
Y44 Agents primarily affecting blood constituents	0.008	0.991	0.000
Y48.3 Local anaesthetics	0.008	0.991	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.008	0.991	0.000
Z63.7 Other stressful life events affecting family and household	0.008	0.992	0.000
Y40.6 Rifamycins	0.008	0.992	0.000
Y54.7 Agents affecting calcification	0.008	0.992	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.008	0.992	0.000
Y40.7 Antifungal antibiotics, systemically used	0.008	0.992	0.000
Y40.4 Tetracyclines	0.008	0.992	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.008	0.992	0.000
Y52.7 Peripheral vasodilators	0.008	0.992	0.000
Y40.0 Penicillins	0.008	0.992	0.000
F33.8 Other recurrent depressive disorders	0.007	0.992	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.007	0.993	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.007	0.993	0.000
Y40.3 Macrolides	0.007	0.993	0.000
A41 Other septicaemia	0.007	0.993	0.000
A41.1 Septicaemia due to other specified staphylococcus	0.007	0.993	0.000
A41.8 Other specified septicaemia	0.007	0.993	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.007	0.993	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.007	0.993	0.000
Z60 Problems related to social environment	0.001	0.993	0.006
Y44.5 Thrombolytic drugs	0.007	0.993	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.007	0.993	0.000
F33.4 Recurrent depressive disorder, currently in remission	0.007	0.993	0.000
F20.0 Paranoid schizophrenia	0.000	0.993	0.007
A41.2 Septicaemia due to unspecified staphylococcus	0.007	0.993	0.000
Y54.4 Loop [high-ceiling] diuretics	0.006	0.993	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.006	0.993	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.006	0.994	0.000
Y44.7 Plasma substitutes	0.006	0.994	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.006	0.994	0.000
F33.0 Recurrent depressive disorder, current episode mild	0.006	0.994	0.000
Z63 Other problems related to primary support group, including family circumstances	0.006	0.994	0.000
R73.9 Hyperglycaemia, unspecified	0.006	0.994	0.000
A41.9 Septicaemia, unspecified	0.006	0.994	0.000
Y44.6 Natural blood and blood products	0.006	0.994	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.006	0.994	0.000
Z63.0 Problems in relationship with spouse or partner	0.006	0.994	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.994	0.006
A41.4 Septicaemia due to anaerobes	0.006	0.994	0.000
A41.0 Septicaemia due to Staphylococcus aureus	0.006	0.994	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.006	0.994	0.000
Y40.9 Systemic antibiotic, unspecified	0.005	0.994	0.000
Z63.4 Disappearance and death of family member	0.006	0.994	0.000
S22.40 Multiple fractures of ribs (closed)	0.000	0.994	0.006
E89.2 Postprocedural hypoparathyroidism	0.005	0.995	0.000
Z63.6 Dependent relative needing care at home	0.005	0.995	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.005	0.995	0.000
A41.3 Septicaemia due to Haemophilus influenzae	0.005	0.995	0.000
Z60.5 Target of perceived adverse discrimination and persecution	0.001	0.995	0.005
Z60.4 Social exclusion and rejection	0.001	0.995	0.005
Z60.3 Acculturation difficulty	0.001	0.995	0.005
Z60.1 Atypical parenting situation	0.001	0.995	0.005
Z60.0 Problems of adjustment to life-cycle transitions	0.001	0.995	0.005
I69.3 Sequelae of cerebral infarction	0.000	0.995	0.005
M79.5 Residual foreign body in soft tissue	0.000	0.995	0.005
A41.5 Septicaemia due to other Gram-negative organisms	0.005	0.995	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.005	0.995	0.000
L08.8 Other specified local infections of skin and subcutaneous tissue	0.000	0.995	0.005
R45.2 Unhappiness	0.005	0.995	0.000
K70.3 Alcoholic cirrhosis of liver	0.005	0.995	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.005	0.995	0.000
Z60.8 Other problems related to social environment	0.001	0.995	0.004
G63.2 Diabetic polyneuropathy	0.005	0.995	0.000
Z63.9 Problem related to primary support group, unspecified	0.005	0.995	0.000
Z63.3 Absence of family member	0.005	0.995	0.000
Z63.2 Inadequate family support	0.005	0.995	0.000
Z63.1 Problems in relationship with parents and in-laws	0.005	0.995	0.000
H02.3 Blepharochalasis	0.000	0.995	0.005
I69 Sequelae of cerebrovascular disease	0.000	0.995	0.005
Z63.8 Other specified problems related to primary support group	0.005	0.995	0.000
Y54.5 Other diuretics	0.004	0.995	0.001
Z60.9 Problem related to social environment, unspecified	0.001	0.995	0.004
S64 Injury of nerves at wrist and hand level	0.005	0.995	0.000
T45.0 Antiallergic and antiemetic drugs	0.005	0.995	0.000
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.004	0.995	0.000
S43.6 Sprain and strain of sternoclavicular joint	0.004	0.995	0.000
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.004	0.995	0.000
S43.2 Dislocation of sternoclavicular joint	0.004	0.995	0.000
S64.0 Injury of ulnar nerve at wrist and hand level	0.005	0.995	0.000
M79.58 Residual foreign body in soft tissue (Other)	0.000	0.995	0.004
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.995	0.005
T46 Poisoning by agents primarily affecting the cardiovascular system	0.005	0.995	0.000
H57.1 Ocular pain	0.000	0.995	0.005
E87.5 Hyperkalaemia	0.004	0.996	0.000
K90 Intestinal malabsorption	0.000	0.996	0.004
T36 Poisoning by systemic antibiotics	0.004	0.996	0.000
S43.5 Sprain and strain of acromioclavicular joint	0.004	0.996	0.000
T36.0 Penicillins	0.004	0.996	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.996	0.004
T46.4 Angiotensin-converting-enzyme inhibitors	0.004	0.996	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.004	0.996	0.000
T86.8 Failure and rejection of other transplanted organs and tissues	0.004	0.996	0.000
R45 Symptoms and signs involving emotional state	0.004	0.996	0.000
H50.1 Divergent concomitant strabismus	0.004	0.996	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.004	0.996	0.000
R45.6 Physical violence	0.004	0.996	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.004	0.996	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.004	0.996	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.004	0.996	0.000
M79.56 Residual foreign body in soft tissue (Lower leg)	0.000	0.996	0.004
Y52.1 Calcium-channel blockers	0.004	0.996	0.000
D06.9 Cervix, unspecified	0.004	0.996	0.000
R45.0 Nervousness	0.004	0.996	0.000
K70.4 Alcoholic hepatic failure	0.004	0.996	0.000
S43.1 Dislocation of acromioclavicular joint	0.004	0.996	0.000
M79.59 Residual foreign body in soft tissue (Site unspecified)	0.000	0.996	0.004
M79.55 Residual foreign body in soft tissue (Pelvic region and thigh)	0.000	0.996	0.004
M79.51 Residual foreign body in soft tissue (Shoulder region)	0.000	0.996	0.004
M79.50 Residual foreign body in soft tissue (Multiple sites)	0.000	0.996	0.004
T45.2 Vitamins, not elsewhere classified	0.004	0.996	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.004	0.996	0.000
R45.1 Restlessness and agitation	0.004	0.996	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.004	0.996	0.000
S52.20 Fracture of shaft of ulna (closed)	0.004	0.996	0.000
M79.57 Residual foreign body in soft tissue (Ankle and foot)	0.000	0.996	0.004
F20 Schizophrenia	0.000	0.996	0.004
Z63.5 Disruption of family by separation and divorce	0.004	0.996	0.000
S64.7 Injury of multiple nerves at wrist and hand level	0.004	0.996	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.004	0.996	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.004	0.996	0.000
T46.1 Calcium-channel blockers	0.004	0.996	0.000
T36.4 Tetracyclines	0.004	0.996	0.000
T36.3 Macrolides	0.004	0.996	0.000
M79.52 Residual foreign body in soft tissue (Upper arm)	0.000	0.996	0.003
S64.9 Injury of unspecified nerve at wrist and hand level	0.003	0.996	0.000
S64.8 Injury of other nerves at wrist and hand level	0.003	0.996	0.000
M79.53 Residual foreign body in soft tissue (Forearm)	0.000	0.996	0.003
K90.8 Other intestinal malabsorption	0.000	0.996	0.003
S43.4 Sprain and strain of shoulder joint	0.003	0.996	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.996	0.004
T46.8 Antivaricose drugs, including sclerosing agents	0.003	0.996	0.000
T46.7 Peripheral vasodilators	0.003	0.996	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.003	0.996	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.003	0.996	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.003	0.996	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.003	0.996	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.003	0.996	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.003	0.996	0.000
S42.30 Fracture of shaft of humerus (closed)	0.000	0.997	0.003
K90.3 Pancreatic steatorrhoea	0.000	0.997	0.003
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.997	0.003
K90.1 Tropical sprue	0.000	0.997	0.003
T36.9 Systemic antibiotic, unspecified	0.003	0.997	0.000
T36.8 Other systemic antibiotics	0.003	0.997	0.000
T36.7 Antifungal antibiotics, systemically used	0.003	0.997	0.000
T36.6 Rifamycins	0.003	0.997	0.000
T36.5 Aminoglycosides	0.003	0.997	0.000
T36.2 Chloramphenicol group	0.003	0.997	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.003	0.997	0.000
R45.5 Hostility	0.003	0.997	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.003	0.997	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.003	0.997	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.003	0.997	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.997	0.003
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.997	0.003
R45.3 Demoralisation and apathy	0.003	0.997	0.000
T41.2 Other and unspecified general anaesthetics	0.003	0.997	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.003	0.997	0.000
T39.0 Salicylates	0.003	0.997	0.000
S82.10 Fracture of upper end of tibia (closed)	0.000	0.997	0.003
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs	0.003	0.997	0.000
K70 Alcoholic liver disease	0.003	0.997	0.000
T40.2 Other opioids	0.003	0.997	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.003	0.997	0.000
T45.8 Other primarily systemic and haematological agents	0.003	0.997	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.003	0.997	0.000
T45.6 Fibrinolysis-affecting drugs	0.003	0.997	0.000
T45.4 Iron and its compounds	0.003	0.997	0.000
T45.3 Enzymes, not elsewhere classified	0.003	0.997	0.000
Y42.5 Other oestrogens and progestogens	0.003	0.997	0.000
L05.9 Pilonidal cyst without abscess	0.000	0.997	0.003
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.003	0.997	0.000
T50.7 Analeptics and opioid receptor antagonists	0.003	0.997	0.000
T50.5 Appetite depressants	0.003	0.997	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.003	0.997	0.000
T50.1 Loop [high-ceiling] diuretics	0.003	0.997	0.000
T50.0 Mineralocorticoids and their antagonists	0.003	0.997	0.000
R45.7 State of emotional shock and stress, unspecified	0.003	0.997	0.000
T38.5 Other oestrogens and progestogens	0.003	0.997	0.000
Y44.2 Anticoagulants	0.003	0.997	0.000
F20.9 Schizophrenia, unspecified	0.000	0.997	0.003
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.003	0.997	0.000
F20.5 Residual schizophrenia	0.000	0.997	0.003
T46.3 Coronary vasodilators, not elsewhere classified	0.003	0.997	0.000
T39.4 Antirheumatics, not elsewhere classified	0.003	0.997	0.000
T39.2 Pyrazolone derivatives	0.003	0.997	0.000
F34 Persistent mood [affective] disorders	0.003	0.997	0.000
S64.3 Injury of digital nerve of thumb	0.003	0.997	0.000
F20.6 Simple schizophrenia	0.000	0.997	0.003
F20.4 Postschizophrenic depression	0.000	0.997	0.003
F20.3 Undifferentiated schizophrenia	0.000	0.997	0.003
F20.2 Catatonic schizophrenia	0.000	0.997	0.003
F20.1 Hebephrenic schizophrenia	0.000	0.997	0.003
F30-F39 Mood [affective] disorders	0.003	0.997	0.000
R45.4 Irritability and anger	0.003	0.997	0.000
T39.1 4-Aminophenol derivatives	0.003	0.997	0.000
T41.5 Therapeutic gases	0.003	0.997	0.000
T41.4 Anaesthetic, unspecified	0.003	0.997	0.000
T41.3 Local anaesthetics	0.003	0.997	0.000
T41.1 Intravenous anaesthetics	0.003	0.997	0.000
T41.0 Inhaled anaesthetics	0.003	0.997	0.000
F20.8 Other schizophrenia	0.000	0.997	0.003
F34.1 Dysthymia	0.003	0.997	0.000
T47.4 Other laxatives	0.003	0.997	0.000
T47.0 Histamine H(2)-receptor antagonists	0.003	0.997	0.000
S64.1 Injury of median nerve at wrist and hand level	0.003	0.997	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.003	0.997	0.000
T50.8 Diagnostic agents	0.003	0.997	0.000
T48.5 Anti-common-cold drugs	0.003	0.997	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.003	0.997	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.003	0.997	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.003	0.997	0.000
T48.4 Expectorants	0.003	0.997	0.000
T48.3 Antitussives	0.003	0.997	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.003	0.997	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.003	0.997	0.000
T48.0 Oxytocic drugs	0.003	0.997	0.000
G63 Polyneuropathy in diseases classified elsewhere	0.003	0.997	0.000
F34.0 Cyclothymia	0.003	0.997	0.000
T38.9 Other and unspecified hormone antagonists	0.003	0.997	0.000
T38.7 Androgens and anabolic congeners	0.003	0.997	0.000
T38.4 Oral contraceptives	0.003	0.997	0.000
T38.2 Antithyroid drugs	0.003	0.997	0.000
T38.0 Glucocorticoids and synthetic analogues	0.003	0.997	0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.003	0.997	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.003	0.997	0.000
T40.3 Methadone	0.003	0.997	0.000
T50.4 Drugs affecting uric acid metabolism	0.003	0.997	0.000
K80.0 Calculus of gallbladder with acute cholecystitis	0.000	0.997	0.003
T47.2 Stimulant laxatives	0.003	0.997	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.003	0.997	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.003	0.997	0.000
T40.8 Lysergide [LSD]	0.003	0.997	0.000
T40.7 Cannabis (derivatives)	0.003	0.997	0.000
T40.0 Opium	0.003	0.997	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.003	0.997	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.003	0.997	0.000
T47.7 Emetics	0.003	0.997	0.000
T47.5 Digestants	0.003	0.997	0.000
T47.3 Saline and osmotic laxatives	0.003	0.997	0.000
J32.8 Other chronic sinusitis	0.003	0.997	0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.003	0.997	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.002	0.997	0.000
T37.5 Antiviral drugs	0.002	0.997	0.000
T37.4 Anthelminthics	0.002	0.997	0.000
T37.3 Other antiprotozoal drugs	0.002	0.997	0.000
T37.1 Antimycobacterial drugs	0.002	0.997	0.000
T37.0 Sulphonamides	0.002	0.997	0.000
T40.1 Heroin	0.003	0.997	0.000
T40.5 Cocaine	0.003	0.997	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.003	0.997	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
T38.1 Thyroid hormones and substitutes	0.002	0.997	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.002	0.997	0.000
T86.0 Bone-marrow transplant rejection	0.003	0.997	0.000
R40.0 Somnolence	0.003	0.997	0.000
T47.6 Antidiarrhoeal drugs	0.002	0.997	0.000
V49.9 Car occupant [any] injured in unspecified traffic accident	0.000	0.997	0.003
F30 Manic episode	0.003	0.997	0.000
F30.9 Manic episode, unspecified	0.003	0.997	0.000
S22.4 Multiple fractures of ribs	0.000	0.997	0.003
K70.1 Alcoholic hepatitis	0.003	0.997	0.000
T49.9 Topical agent, unspecified	0.002	0.997	0.000
T49.8 Other topical agents	0.002	0.997	0.000
T49.7 Dental drugs, topically applied	0.002	0.997	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.002	0.997	0.000
T49.5 Ophthalmological drugs and preparations	0.002	0.997	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.002	0.997	0.000
T49.3 Emollients, demulcents and protectants	0.002	0.997	0.000
T49.2 Local astringents and local detergents	0.002	0.997	0.000
T49.1 Antipruritics	0.002	0.997	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.002	0.997	0.000
F34.9 Persistent mood [affective] disorder, unspecified	0.002	0.997	0.000
F34.8 Other persistent mood [affective] disorders	0.002	0.997	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.000	0.997	0.003
T37.8 Other specified systemic anti-infectives and antiparasitics	0.002	0.998	0.000
T40.6 Other and unspecified narcotics	0.002	0.998	0.000
F38 Other mood [affective] disorders	0.002	0.998	0.000
R45.8 Other symptoms and signs involving emotional state	0.002	0.998	0.000
T86 Failure and rejection of transplanted organs and tissues	0.002	0.998	0.000
N95.8 Other specified menopausal and perimenopausal disorders	0.002	0.998	0.000
R52.9 Pain, unspecified	0.000	0.998	0.002
S40.0 Contusion of shoulder and upper arm	0.002	0.998	0.000
T43.6 Psychostimulants with abuse potential	0.002	0.998	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.002	0.998	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.002	0.998	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.002	0.998	0.000
G63.8 Polyneuropathy in other diseases classified elsewhere	0.002	0.998	0.000
G63.6 Polyneuropathy in other musculoskeletal disorders	0.002	0.998	0.000
G63.5 Polyneuropathy in systemic connective tissue disorders	0.002	0.998	0.000
G63.4 Polyneuropathy in nutritional deficiency	0.002	0.998	0.000
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.002	0.998	0.000
G63.1 Polyneuropathy in neoplastic disease	0.002	0.998	0.000
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
G96.0 Cerebrospinal fluid leak	0.000	0.998	0.002
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.002	0.998	0.000
X23.9 Unspecified place	0.000	0.998	0.002
D12.4 Descending colon	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations