TreeWAS – Variant ID: rs721424

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E29.1 Testicular hypofunction	0.000	0.923	0.077
E29 Testicular dysfunction	0.000	0.939	0.061
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.945	0.055
E27 Other disorders of adrenal gland	0.000	0.945	0.055
E20-E35 Disorders of other endocrine glands	0.000	0.950	0.050
E27.1 Primary adrenocortical insufficiency	0.000	0.951	0.049
E27.2 Addisonian crisis	0.000	0.952	0.048
E27.8 Other specified disorders of adrenal gland	0.000	0.953	0.047
E29.9 Testicular dysfunction, unspecified	0.000	0.955	0.045
E29.8 Other testicular dysfunction	0.000	0.956	0.044
E29.0 Testicular hyperfunction	0.000	0.956	0.044
E22 Hyperfunction of pituitary gland	0.000	0.956	0.044
E34 Other endocrine disorders	0.000	0.956	0.044
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.960	0.040
E27.5 Adrenomedullary hyperfunction	0.000	0.960	0.040
E27.0 Other adrenocortical overactivity	0.000	0.960	0.040
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.961	0.039
E31 Polyglandular dysfunction	0.000	0.963	0.037
E34.0 Carcinoid syndrome	0.000	0.963	0.037
E34.8 Other specified endocrine disorders	0.000	0.964	0.036
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.964	0.036
E30 Disorders of puberty, not elsewhere classified	0.000	0.964	0.036
E22.1 Hyperprolactinaemia	0.000	0.965	0.035
E34.3 Short stature, not elsewhere classified	0.000	0.966	0.034
E25 Adrenogenital disorders	0.000	0.967	0.033
E26 Hyperaldosteronism	0.000	0.968	0.032
E32 Diseases of thymus	0.000	0.968	0.032
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.968	0.031
E22.8 Other hyperfunction of pituitary gland	0.000	0.968	0.031
E34.5 Androgen resistance syndrome	0.000	0.968	0.031
E34.4 Constitutional tall stature	0.000	0.968	0.031
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.968	0.031
E34.1 Other hypersecretion of intestinal hormones	0.000	0.968	0.031
E34.9 Endocrine disorder, unspecified	0.000	0.971	0.029
E20 Hypoparathyroidism	0.000	0.972	0.028
E31.0 Autoimmune polyglandular failure	0.000	0.972	0.028
E24 Cushing's syndrome	0.000	0.972	0.028
E31.9 Polyglandular dysfunction, unspecified	0.000	0.973	0.027
E31.8 Other polyglandular dysfunction	0.000	0.973	0.027
E31.1 Polyglandular hyperfunction	0.000	0.973	0.027
E30.9 Disorder of puberty, unspecified	0.000	0.974	0.026
E30.8 Other disorders of puberty	0.000	0.974	0.026
E30.1 Precocious puberty	0.000	0.974	0.026
E30.0 Delayed puberty	0.000	0.974	0.026
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.974	0.026
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.974	0.026
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.974	0.026
E27.9 Disorder of adrenal gland, unspecified	0.000	0.974	0.026
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.975	0.025
E23 Hypofunction and other disorders of pituitary gland	0.000	0.976	0.024
E22.0 Acromegaly and pituitary gigantism	0.000	0.976	0.024
E25.9 Adrenogenital disorder, unspecified	0.000	0.976	0.024
E25.8 Other adrenogenital disorders	0.000	0.976	0.024
E26.8 Other hyperaldosteronism	0.000	0.976	0.023
E26.1 Secondary hyperaldosteronism	0.000	0.976	0.023
E32.8 Other diseases of thymus	0.000	0.977	0.023
E32.1 Abscess of thymus	0.000	0.977	0.023
E32.0 Persistent hyperplasia of thymus	0.000	0.977	0.023
E26.0 Primary hyperaldosteronism	0.000	0.977	0.023
O62.2 Other uterine inertia	0.000	0.978	0.022
E28 Ovarian dysfunction	0.000	0.978	0.021
E26.9 Hyperaldosteronism, unspecified	0.000	0.979	0.021
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.979	0.021
E20.1 Pseudohypoparathyroidism	0.000	0.980	0.020
E20.0 Idiopathic hypoparathyroidism	0.000	0.980	0.020
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.980	0.020
E24.3 Ectopic ACTH syndrome	0.000	0.980	0.020
E24.1 Nelson's syndrome	0.000	0.980	0.020
E21.0 Primary hyperparathyroidism	0.000	0.980	0.020
E24.2 Drug-induced Cushing's syndrome	0.000	0.980	0.020
E24.8 Other Cushing's syndrome	0.000	0.980	0.020
E32.9 Disease of thymus, unspecified	0.000	0.980	0.019
E24.0 Pituitary-dependent Cushing's disease	0.000	0.980	0.019
E21.3 Hyperparathyroidism, unspecified	0.000	0.981	0.019
E20.8 Other hypoparathyroidism	0.000	0.981	0.019
E23.2 Diabetes insipidus	0.000	0.981	0.019
E23.1 Drug-induced hypopituitarism	0.000	0.982	0.017
E21.4 Other specified disorders of parathyroid gland	0.000	0.983	0.017
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.983	0.017
E23.6 Other disorders of pituitary gland	0.000	0.984	0.016
E28.9 Ovarian dysfunction, unspecified	0.000	0.984	0.015
E28.8 Other ovarian dysfunction	0.000	0.984	0.015
E28.1 Androgen excess	0.000	0.984	0.015
E28.0 Oestrogen excess	0.000	0.984	0.015
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.985	0.015
E20.9 Hypoparathyroidism, unspecified	0.000	0.985	0.015
E21.2 Other hyperparathyroidism	0.000	0.985	0.014
E24.9 Cushing's syndrome, unspecified	0.000	0.986	0.014
E23.0 Hypopituitarism	0.000	0.987	0.013
E23.7 Disorder of pituitary gland, unspecified	0.000	0.987	0.013
Z90.6 Acquired absence of other parts of urinary tract	0.000	0.988	0.012
E28.3 Primary ovarian failure	0.000	0.988	0.012
O62 Abnormalities of forces of labour	0.000	0.988	0.012
O62.0 Primary inadequate contractions	0.000	0.988	0.012
D25.2 Subserosal leiomyoma of uterus	0.011	0.989	0.000
M22.4 Chondromalacia patellae	0.000	0.990	0.010
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.001	0.990	0.009
E28.2 Polycystic ovarian syndrome	0.000	0.991	0.009
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.000	0.991	0.009
O62.8 Other abnormalities of forces of labour	0.000	0.991	0.009
D21.2 Connective and other soft tissue of lower limb, including hip	0.009	0.991	0.000
O62.9 Abnormality of forces of labour, unspecified	0.000	0.991	0.009
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.009	0.991	0.000
S32.40 Fracture of acetabulum (closed)	0.000	0.993	0.007
D21 Other benign neoplasms of connective and other soft tissue	0.007	0.993	0.000
O62.3 Precipitate labour	0.000	0.993	0.007
D21.4 Connective and other soft tissue of abdomen	0.007	0.993	0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.000	0.993	0.007
D21.1 Connective and other soft tissue of upper limb, including shoulder	0.006	0.994	0.000
O62.1 Secondary uterine inertia	0.000	0.994	0.006
D21.5 Connective and other soft tissue of pelvis	0.006	0.994	0.000
D21.6 Connective and other soft tissue of trunk, unspecified	0.006	0.994	0.000
D21.0 Connective and other soft tissue of head, face and neck	0.005	0.994	0.000
F06.7 Mild cognitive disorder	0.006	0.994	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.995	0.005
D21.3 Connective and other soft tissue of thorax	0.005	0.995	0.000
D21.9 Connective and other soft tissue, unspecified	0.005	0.995	0.000
G45.4 Transient global amnesia	0.000	0.995	0.005
H02.1 Ectropion of eyelid	0.000	0.995	0.005
S32.4 Fracture of acetabulum	0.000	0.995	0.005
E03.8 Other specified hypothyroidism	0.000	0.996	0.004
U80.1 Methicillin resistant agent	0.004	0.996	0.000
M94.26 Chondromalacia (Lower leg)	0.000	0.996	0.004
I82.9 Embolism and thrombosis of unspecified vein	0.000	0.996	0.004
E06.9 Thyroiditis, unspecified	0.000	0.996	0.004
S32.41 Fracture of acetabulum (open)	0.000	0.996	0.004
E78.2 Mixed hyperlipidaemia	0.004	0.996	0.000
Z63.4 Disappearance and death of family member	0.000	0.996	0.004
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.004	0.996	0.000
M54.39 Sciatica (Site unspecified)	0.000	0.996	0.004
K22.8 Other specified diseases of oesophagus	0.004	0.996	0.000
Z63 Other problems related to primary support group, including family circumstances	0.000	0.996	0.003
N41.0 Acute prostatitis	0.003	0.997	0.000
U80.0 Penicillin resistant agent	0.003	0.997	0.000
Z63.7 Other stressful life events affecting family and household	0.000	0.997	0.003
U80 Agent resistant to penicillin and related antibiotics	0.003	0.997	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.000	0.997	0.003
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease	0.003	0.997	0.000
Z29.2 Other prophylactic chemotherapy	0.000	0.997	0.003
Z63.0 Problems in relationship with spouse or partner	0.000	0.997	0.003
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.000	0.997	0.003
S32 Fracture of lumbar spine and pelvis	0.000	0.997	0.003
F06.2 Organic delusional [schizophrenia-like] disorder	0.003	0.997	0.000
S32.7 Multiple fractures of lumbar spine and pelvis	0.000	0.997	0.003
Z63.6 Dependent relative needing care at home	0.000	0.997	0.003
F06.6 Organic emotionally labile [asthenic] disorder	0.003	0.997	0.000
F06.5 Organic dissociative disorder	0.003	0.997	0.000
F06.4 Organic anxiety disorder	0.003	0.997	0.000
F06.1 Organic catatonic disorder	0.003	0.997	0.000
F06.0 Organic hallucinosis	0.003	0.997	0.000
S32.3 Fracture of ilium	0.000	0.997	0.003
I65.2 Occlusion and stenosis of carotid artery	0.003	0.997	0.000
S12.20 Fracture of other specified cervical vertebra (closed)	0.003	0.997	0.000
Z63.5 Disruption of family by separation and divorce	0.000	0.997	0.003
S32.30 Fracture of ilium (closed)	0.000	0.997	0.003
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease	0.003	0.997	0.000
M94.2 Chondromalacia	0.000	0.997	0.003
H60.1 Cellulitis of external ear	0.000	0.997	0.003
Z63.9 Problem related to primary support group, unspecified	0.000	0.997	0.003
Z63.3 Absence of family member	0.000	0.997	0.003
Z63.2 Inadequate family support	0.000	0.997	0.003
Z63.1 Problems in relationship with parents and in-laws	0.000	0.997	0.003
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.003	0.997	0.000
M87.96 Osteonecrosis, unspecified (Lower leg)	0.000	0.997	0.003
M87.9 Osteonecrosis, unspecified	0.000	0.997	0.003
M91.20 Coxa plana-Mult sites	0.000	0.997	0.003
H36.0 Diabetic retinopathy	0.000	0.997	0.003
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.000	0.997	0.003
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.000	0.997	0.003
S32.1 Fracture of sacrum	0.000	0.997	0.003
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.997	0.003
F06.3 Organic mood [affective] disorders	0.002	0.997	0.000
L89.1 Stage II decubitus ulcer	0.003	0.997	0.000
E06 Thyroiditis	0.000	0.997	0.003
U51 Admission status on psychiatric patients	0.003	0.997	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.997	0.003
N99.8 Other postprocedural disorders of genito-urinary system	0.000	0.997	0.003
E03 Other hypothyroidism	0.000	0.997	0.003
F07.2 Postconcussional syndrome	0.002	0.997	0.000
S32.2 Fracture of coccyx	0.000	0.998	0.002
S32.71 Multiple fractures of lumbar spine and pelvis (open)	0.000	0.998	0.002
N92.4 Excessive bleeding in the premenopausal period	0.000	0.998	0.002
U81 Agent resistant to vancomycin and related antibiotics	0.002	0.998	0.000
Y40.9 Systemic antibiotic, unspecified	0.002	0.998	0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.002	0.998	0.000
F02 Dementia in other diseases classified elsewhere	0.002	0.998	0.000
F05.0 Delirium not superimposed on dementia, so described	0.002	0.998	0.000
U51.1 Previously admitted to a psychiatric hospital of the provider	0.002	0.998	0.000
S32.31 Fracture of ilium (open)	0.000	0.998	0.002
O26.2 Pregnancy care of habitual aborter	0.002	0.998	0.000
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.000	0.998	0.002
M77.91 Enthesopathy, unspecified (Shoulder region)	0.002	0.998	0.000
E03.1 Congenital hypothyroidism without goitre	0.000	0.998	0.002
F07.9 Unspecified organic personality and behavioural disorder due to brain disease, damage and dysfunction	0.002	0.998	0.000
U81.0 Vancomycin resistant agent	0.002	0.998	0.000
Z63.8 Other specified problems related to primary support group	0.000	0.998	0.002
F05 Delirium, not induced by alcohol and other psychoactive substances	0.002	0.998	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
M94.29 Chondromalacia (Site unspecified)	0.000	0.998	0.002
M94.28 Chondromalacia (Other)	0.000	0.998	0.002
M94.27 Chondromalacia (Ankle and foot)	0.000	0.998	0.002
M94.25 Chondromalacia (Pelvic region and thigh)	0.000	0.998	0.002
M94.24 Chondromalacia (Hand)	0.000	0.998	0.002
M94.23 Chondromalacia (Forearm)	0.000	0.998	0.002
M94.22 Chondromalacia (Upper arm)	0.000	0.998	0.002
M94.21 Chondromalacia (Shoulder region)	0.000	0.998	0.002
M94.20 Chondromalacia (Multiple sites)	0.000	0.998	0.002
F02.8 Dementia in other specified diseases classified elsewhere	0.002	0.998	0.000
F02.0 Dementia in Pick's disease	0.002	0.998	0.000
Z59.9 Problem relating to housing and economic circumstances, unspecified	0.000	0.998	0.002
E13.9 Without complications	0.000	0.998	0.002
Z58.8 Other problems related to physical environment	0.000	0.998	0.002
S32.10 Fracture of sacrum (closed)	0.000	0.998	0.002
M91.2 Coxa plana	0.000	0.998	0.002
U51.0 Not Previously admitted to a psyciatric hospital	0.002	0.998	0.000
K29.0 Acute haemorrhagic gastritis	0.002	0.998	0.000
U50 Level of care administered to neonates	0.002	0.998	0.000
U07 Emergency use of U07	0.002	0.998	0.000
U06 Emergency use of U06	0.002	0.998	0.000
U04 Severe acute respiratory syndrome [SARS]	0.002	0.998	0.000
U52 First in a series of a regular day/night admissions	0.002	0.998	0.000
S02.60 Fracture of mandible (closed)	0.002	0.998	0.000
M87.99 Osteonecrosis, unspecified (Site unspecified)	0.000	0.998	0.002
M87.94 Osteonecrosis, unspecified (Hand)	0.000	0.998	0.002
M87.93 Osteonecrosis, unspecified (Forearm)	0.000	0.998	0.002
M87.92 Osteonecrosis, unspecified (Upper arm)	0.000	0.998	0.002
M87.90 Osteonecrosis, unspecified (Multiple sites)	0.000	0.998	0.002
M87.98 Osteonecrosis, unspecified (Other)	0.000	0.998	0.002
F00-F09 Organic, including symptomatic, mental disorders	0.002	0.998	0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.000	0.998	0.002
M62.59 Muscle wasting and atrophy, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
S32.81 Fracture of other and unspecified parts of lumbar spine and pelvis (open)	0.000	0.998	0.002
E14.3 With ophthalmic complications	0.000	0.998	0.002
O21.9 Vomiting of pregnancy, unspecified	0.002	0.998	0.000
E06.5 Other chronic thyroiditis	0.000	0.998	0.002
I12.9 Hypertensive renal disease without renal failure	0.002	0.998	0.000
S32.11 Fracture of sacrum (open)	0.000	0.998	0.002
K86.3 Pseudocyst of pancreas	0.000	0.998	0.002
E06.4 Drug-induced thyroiditis	0.000	0.998	0.002
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.998	0.002
E06.1 Subacute thyroiditis	0.000	0.998	0.002
E06.0 Acute thyroiditis	0.000	0.998	0.002
U51.2 Previously admitted to a psychiatric hospital of another provider	0.002	0.998	0.000
Z58 Problems related to physical environment	0.000	0.998	0.002
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.998	0.002
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.998	0.002
E03.5 Myxoedema coma	0.000	0.998	0.002
E03.4 Atrophy of thyroid (acquired)	0.000	0.998	0.002
E03.3 Postinfectious hypothyroidism	0.000	0.998	0.002
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.998	0.002
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.998	0.002
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.998	0.002
F02.3 Dementia in Parkinson's disease	0.002	0.998	0.000
X49.9 Unspecified place	0.002	0.998	0.000
S32.21 Fracture of coccyx (open)	0.000	0.998	0.002
S32.20 Fracture of coccyx (closed)	0.000	0.998	0.002
Y43.4 Immunosuppressive agents	0.002	0.998	0.000
Z59 Problems related to housing and economic circumstances	0.000	0.998	0.002
S42.10 Fracture of scapula (closed)	0.000	0.998	0.002
K45.8 Other specified abdominal hernia without obstruction or gangrene	0.000	0.998	0.002
O26.0 Excessive weight gain in pregnancy	0.002	0.998	0.000
Z85.9 Personal history of malignant neoplasm, unspecified	0.002	0.998	0.000
O21 Excessive vomiting in pregnancy	0.002	0.998	0.000
Z61 Problems related to negative life events in childhood	0.000	0.998	0.002
E06.3 Autoimmune thyroiditis	0.000	0.998	0.002
O26 Maternal care for other conditions predominantly related to pregnancy	0.002	0.998	0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.002	0.998	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.000	0.998	0.002
O26.8 Other specified pregnancy-related conditions	0.002	0.998	0.000
Z58.7 Exposure to tobacco smoke	0.000	0.998	0.002
F05.8 Other delirium	0.002	0.998	0.000
F07.8 Other organic personality and behavioural disorders due to brain disease, damage and dysfunction	0.002	0.998	0.000
F07.1 Postencephalitic syndrome	0.002	0.998	0.000
F02.4 Dementia in human immunodeficiency virus [HIV] disease	0.002	0.998	0.000
F02.2 Dementia in Huntington's disease	0.002	0.998	0.000
F02.1 Dementia in Creutzfeldt-Jakob disease	0.002	0.998	0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.002	0.998	0.000
U81.8 Agent resistant to other vancomycin-related antibiotic	0.002	0.998	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.998	0.002
D16.2 Long bones of lower limb	0.002	0.998	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.002	0.998	0.000
M77.97 Enthesopathy, unspecified (Ankle and foot)	0.002	0.998	0.000
M77.94 Enthesopathy, unspecified (Hand)	0.002	0.998	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.002	0.998	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.002	0.998	0.000
Y44.2 Anticoagulants	0.002	0.998	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.002	0.998	0.000
K41 Femoral hernia	0.000	0.998	0.002
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.998	0.002
I42.9 Cardiomyopathy, unspecified	0.000	0.998	0.002
O24 Diabetes mellitus in pregnancy	0.002	0.998	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.998	0.002
F05.9 Delirium, unspecified	0.002	0.998	0.000
O20.8 Other haemorrhage in early pregnancy	0.002	0.998	0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.000	0.998	0.002
O20-O29 Other maternal disorders predominantly related to pregnancy	0.002	0.998	0.000
N99.5 Malfunction of external stoma of urinary tract	0.000	0.998	0.002
T92.2 Sequelae of fracture at wrist and hand level	0.000	0.998	0.002
Y44.5 Thrombolytic drugs	0.002	0.998	0.000
Z61.5 Problems related to alleged sexual abuse of child by person outside primary support group	0.000	0.998	0.002
R52.1 Chronic intractable pain	0.000	0.998	0.002
M91 Juvenile osteochondrosis of hip and pelvis	0.000	0.998	0.002
M62.80 Other specified disorders of muscle (Multiple sites)	0.002	0.998	0.000
M91.29 Coxa plana-Site unspec	0.000	0.998	0.002
M91.28 Coxa plana-Other	0.000	0.998	0.002
M91.27 Coxa plana-Ankle/Foot	0.000	0.998	0.002
M91.26 Coxa plana-Lower Leg	0.000	0.998	0.002
M91.25 Coxa plana-Pelvic/Thigh	0.000	0.998	0.002
M91.24 Coxa plana-Hand	0.000	0.998	0.002
M91.23 Coxa plana-Forearm	0.000	0.998	0.002
M91.22 Coxa plana-Upper arm	0.000	0.998	0.002
M91.21 Coxa plana-Shldr region	0.000	0.998	0.002
M62.8 Other specified disorders of muscle	0.002	0.998	0.000
U04.9 Severe acute respiratory syndrome [SARS], unspecified	0.002	0.998	0.000
U06.9 Emergency use of U06.9	0.002	0.998	0.000
U06.8 Emergency use of U06.8	0.002	0.998	0.000
U06.7 Emergency use of U06.7	0.002	0.998	0.000
U06.6 Emergency use of U06.6	0.002	0.998	0.000
U06.5 Emergency use of U06.5	0.002	0.998	0.000
U06.4 Emergency use of U06.4	0.002	0.998	0.000
U06.3 Emergency use of U06.3	0.002	0.998	0.000
U06.2 Emergency use of U06.2	0.002	0.998	0.000
U06.1 Emergency use of U06.1	0.002	0.998	0.000
U06.0 Emergency use of U06.0	0.002	0.998	0.000
U07.9 Emergency use of U07.9	0.002	0.998	0.000
U07.8 Emergency use of U07.8	0.002	0.998	0.000
U07.7 Emergency use of U07.7	0.002	0.998	0.000
U07.6 Emergency use of U07.6	0.002	0.998	0.000
U07.5 Emergency use of U07.5	0.002	0.998	0.000
U07.4 Emergency use of U07.4	0.002	0.998	0.000
U07.3 Emergency use of U07.3	0.002	0.998	0.000
U07.2 Emergency use of U07.2	0.002	0.998	0.000
U07.1 Emergency use of U07.1	0.002	0.998	0.000
U07.0 Emergency use of U07.0	0.002	0.998	0.000
U50.9 Inquest Adjourned Death	0.002	0.998	0.000
U50.3 Level of care administered to neonates (Maximal Intensive Care)	0.002	0.998	0.000
U50.2 Level of care administered to neonates (High Dependancy Intensive Care)	0.002	0.998	0.000
U50.1 Level of care administered to neonates (Special Care)	0.002	0.998	0.000
U50.0 Level of care administered to neonates (Normal Care)	0.002	0.998	0.000
Z29.0 Isolation	0.000	0.998	0.002
Z29 Need for other prophylactic measures	0.000	0.998	0.002
M46.46 Discitis, unspecified (Lumbar region)	0.002	0.998	0.000
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.000	0.998	0.002
C67.1 Dome of bladder	0.002	0.998	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.000	0.998	0.002
L56.8 Other specified acute skin changes due to ultraviolet radiation	0.002	0.998	0.000
O21.2 Late vomiting of pregnancy	0.002	0.998	0.000
Z61.4 Problems related to alleged sexual abuse of child by person within primary support group	0.000	0.998	0.002
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.002	0.998	0.000
Z62 Other problems related to upbringing	0.000	0.998	0.002
Z55 Problems related to education and literacy	0.000	0.998	0.002
F07.0 Organic personality disorder	0.002	0.998	0.000
M77.9 Enthesopathy, unspecified	0.002	0.998	0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O69.2 Labour and delivery complicated by other cord entanglement	0.000	0.998	0.002
R23.8 Other and unspecified skin changes	0.002	0.998	0.000
F05.1 Delirium superimposed on dementia	0.002	0.998	0.000
M91.1 Juvenile osteochondrosis of head of femur [Legg-Calve-Perthes]	0.000	0.998	0.002
S32.5 Fracture of pubis	0.000	0.998	0.002
Z59.8 Other problems relating to housing and economic circumstances	0.000	0.998	0.002
O20 Haemorrhage in early pregnancy	0.002	0.998	0.000
Z64 Problems related to certain psychosocial circumstances	0.000	0.998	0.002
M91.15 Juv osteochondrosis head of femur [Legg-Calve-Perthes]-Pelv	0.000	0.998	0.002
C67.2 Lateral wall of bladder	0.002	0.998	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.002	0.998	0.000
S19.9 Unspecified injury of neck	0.002	0.998	0.000
Z58.9 Problem related to physical environment, unspecified	0.000	0.998	0.002
Z58.6 Inadequate drinking-water supply	0.000	0.998	0.002
Z58.4 Exposure to radiation	0.000	0.998	0.002
Z58.3 Exposure to soil pollution	0.000	0.998	0.002
Z58.2 Exposure to water pollution	0.000	0.998	0.002
Z58.0 Exposure to noise	0.000	0.998	0.002
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.002	0.998	0.000
Z56.3 Stressful work schedule	0.000	0.998	0.002
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.998	0.002
M62.51 Muscle wasting and atrophy, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
L89.0 Stage I decubitus ulcer and pressure area	0.002	0.998	0.000
S12.2 Fracture of other specified cervical vertebra	0.002	0.998	0.000
M62 Other disorders of muscle	0.002	0.998	0.000
O23 Infections of genito-urinary tract in pregnancy	0.002	0.998	0.000
M62.58 Muscle wasting and atrophy, not elsewhere classified (Other)	0.002	0.998	0.000
Y49.2 Other and unspecified antidepressants	0.002	0.998	0.000
Z29.8 Other specified prophylactic measures	0.000	0.998	0.002
Z59.7 Insufficient social insurance and welfare support	0.000	0.998	0.002
Z59.6 Low income	0.000	0.998	0.002
Z59.5 Extreme poverty	0.000	0.998	0.002
Z59.3 Problems related to living in residential institution	0.000	0.998	0.002
Z57 Occupational exposure to risk-factors	0.000	0.998	0.002
M62.55 Muscle wasting and atrophy, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
H34.8 Other retinal vascular occlusions	0.000	0.998	0.002
O26.4 Herpes gestationis	0.002	0.998	0.000
O26.1 Low weight gain in pregnancy	0.002	0.998	0.000
Y84.2 Radiological procedure and radiotherapy	0.000	0.998	0.002
Z59.0 Homelessness	0.000	0.998	0.002
Z61.9 Negative life events in childhood, unspecified	0.000	0.998	0.002
Z61.8 Other negative life events in childhood	0.000	0.998	0.002
Z61.7 Personal frightening experience in childhood	0.000	0.998	0.002
Z61.3 Events resulting in loss of self-esteem in childhood	0.000	0.998	0.002
Z61.2 Altered pattern of family relationships in childhood	0.000	0.998	0.002
Z61.1 Removal from home in childhood	0.000	0.998	0.002
Z61.0 Loss of love relationship in childhood	0.000	0.998	0.002
E13 Other specified diabetes mellitus	0.000	0.998	0.002
Z56 Problems related to employment and unemployment	0.000	0.998	0.002
O21.8 Other vomiting complicating pregnancy	0.002	0.998	0.000
O21.0 Mild hyperemesis gravidarum	0.002	0.998	0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.002	0.998	0.000
Y40.3 Macrolides	0.002	0.998	0.000
M62.84 Other specified disorders of muscle (Hand)	0.002	0.998	0.000
M77.95 Enthesopathy, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
K41.2 Bilateral femoral hernia, without obstruction or gangrene	0.000	0.998	0.002
O26.5 Maternal hypotension syndrome	0.002	0.998	0.000
Z58.5 Exposure to other pollution	0.000	0.998	0.002
Z59.4 Lack of adequate food	0.000	0.998	0.002
M62.57 Muscle wasting and atrophy, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
M62.53 Muscle wasting and atrophy, not elsewhere classified (Forearm)	0.002	0.998	0.000
M62.52 Muscle wasting and atrophy, not elsewhere classified (Upper arm)	0.002	0.998	0.000
M62.50 Muscle wasting and atrophy, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
M62.89 Other specified disorders of muscle (Site unspecified)	0.002	0.998	0.000
O23.5 Infections of the genital tract in pregnancy	0.002	0.998	0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.000	0.998	0.002
M62.54 Muscle wasting and atrophy, not elsewhere classified (Hand)	0.002	0.998	0.000
M62.86 Other specified disorders of muscle (Lower leg)	0.002	0.998	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.002	0.998	0.000
K41.1 Bilateral femoral hernia, with gangrene	0.000	0.998	0.002
K41.0 Bilateral femoral hernia, with obstruction, without gangrene	0.000	0.998	0.002
M62.9 Disorder of muscle, unspecified	0.002	0.998	0.000
O24.3 Pre-existing diabetes mellitus, unspecified	0.002	0.998	0.000
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.002	0.998	0.000
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.002	0.998	0.000
E11.3 With ophthalmic complications	0.000	0.998	0.002
F09 Unspecified organic or symptomatic mental disorder	0.001	0.998	0.000
M94 Other disorders of cartilage	0.000	0.998	0.002
Y44 Agents primarily affecting blood constituents	0.002	0.998	0.000
Z65 Problems related to other psychosocial circumstances	0.000	0.998	0.002
M62.2 Ischaemic infarction of muscle	0.002	0.998	0.000
O29 Complications of anaesthesia during pregnancy	0.002	0.998	0.000
O25 Malnutrition in pregnancy	0.002	0.998	0.000
M91.9 Juvenile osteochondrosis of hip and pelvis, unspecified	0.000	0.998	0.001
M91.8 Other juvenile osteochondrosis of hip and pelvis	0.000	0.998	0.001
M91.3 Pseudocoxalgia	0.000	0.998	0.001
M91.0 Juvenile osteochondrosis of pelvis	0.000	0.998	0.001
O23.4 Unspecified infection of urinary tract in pregnancy	0.002	0.998	0.000
Z61.6 Problems related to alleged physical abuse of child	0.000	0.998	0.001
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.002	0.998	0.000
O23.0 Infections of kidney in pregnancy	0.001	0.998	0.000
O24.9 Diabetes mellitus in pregnancy, unspecified	0.001	0.998	0.000
Z29.9 Prophylactic measure, unspecified	0.000	0.998	0.001
Z59.2 Discord with neighbours, lodgers and landlord	0.000	0.998	0.001
M77.99 Enthesopathy, unspecified (Site unspecified)	0.001	0.998	0.000
M77.98 Enthesopathy, unspecified (Other)	0.001	0.998	0.000
M77.90 Enthesopathy, unspecified (Multiple sites)	0.001	0.998	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.000	0.998	0.002
M62.0 Diastasis of muscle	0.001	0.998	0.000
S32.0 Fracture of lumbar vertebra	0.000	0.998	0.001
Y41.0 Sulphonamides	0.002	0.998	0.000
Z55.9 Problems relating to education and literacy, unspecified	0.000	0.998	0.001
Z55.8 Other problems relating to education and literacy	0.000	0.998	0.001
Z55.4 Educational maladjustment and discord with teachers and classmates	0.000	0.998	0.001
Z55.3 Underachievement in school	0.000	0.998	0.001
Z55.2 Failed examinations	0.000	0.998	0.001
Z55.1 Schooling unavailable and unattainable	0.000	0.998	0.001
Z55.0 Illiteracy and low-level literacy	0.000	0.998	0.001
Z62.9 Problem related to upbringing, unspecified	0.000	0.998	0.001
Z62.8 Other specified problems related to upbringing	0.000	0.998	0.001
Z62.6 Inappropriate parental pressure and other abnormal qualities of upbringing	0.000	0.998	0.001
Z62.5 Other problems related to neglect in upbringing	0.000	0.998	0.001
Z62.4 Emotional neglect of child	0.000	0.998	0.001
Z62.3 Hostility towards and scapegoating of child	0.000	0.998	0.001
Z62.2 Institutional upbringing	0.000	0.998	0.001
Z62.1 Parental overprotection	0.000	0.998	0.001
Z62.0 Inadequate parental supervision and control	0.000	0.998	0.001
Y41 Other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
M62.56 Muscle wasting and atrophy, not elsewhere classified (Lower leg)	0.001	0.998	0.000
M77.93 Enthesopathy, unspecified (Forearm)	0.001	0.998	0.000
M91.19 Juv osteochondrosis head of femur [Legg-Calve-Perthes]-Site	0.000	0.998	0.001
M91.18 Juv osteochondrosis head of femur [Legg-Calve-Perthes]-Othe	0.000	0.998	0.001
M91.17 Juv osteochondrosis head of femur [Legg-Calve-Perthes]-Ankl	0.000	0.998	0.001
M91.16 Juv osteochondrosis head of femur [Legg-Calve-Perthes]-Lowe	0.000	0.998	0.001
M91.14 Juv osteochondrosis head of femur [Legg-Calve-Perthes]-Hand	0.000	0.998	0.001
M91.13 Juv osteochondrosis head of femur [Legg-Calve-Perthes]-Fore	0.000	0.998	0.001
M91.12 Juv osteochondrosis head of femur [Legg-Calve-Perthes]-Uppe	0.000	0.998	0.001
M91.11 Juv osteochondrosis head of femur [Legg-Calve-Perthes]-Shld	0.000	0.998	0.001
M91.10 Juv osteochondrosis head of femur [Legg-Calve-Perthes]-Mult	0.000	0.998	0.001
D16.5 Lower jaw bone	0.002	0.998	0.000
L89.9 Decubitus ulcer and pressure area, unspecified	0.002	0.998	0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.001	0.998	0.000
Y41.5 Antiviral drugs	0.002	0.998	0.000
Z57.8 Occupational exposure to other risk-factors	0.000	0.998	0.002
L89 Decubitus ulcer	0.002	0.998	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.998	0.002
M77.96 Enthesopathy, unspecified (Lower leg)	0.001	0.998	0.000
S32.51 Fracture of pubis (open)	0.000	0.998	0.001
S72.40 Fracture of lower end of femur (closed)	0.002	0.998	0.000
I65.1 Occlusion and stenosis of basilar artery	0.001	0.998	0.000
K41.4 Unilateral or unspecified femoral hernia, with gangrene	0.000	0.998	0.001
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.001	0.998	0.000
Z64.4 Discord with counsellors	0.000	0.998	0.001
Z64.3 Seeking and accepting behavioural and psychological interventions known to be hazardous and harmful	0.000	0.998	0.001
Z64.2 Seeking and accepting physical, nutritional and chemical interventions known to be hazardous and harmful	0.000	0.998	0.001
Z64.1 Problems related to multiparity	0.000	0.998	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations