TreeWAS – Variant ID: rs7224488

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.359	0.641	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.357	0.643	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.356	0.644	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.350	0.650	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.334	0.666	0.000
T43.2 Other and unspecified antidepressants	0.330	0.670	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.315	0.685	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.309	0.691	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.301	0.699	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.300	0.699	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.299	0.701	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.293	0.707	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.288	0.712	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.279	0.721	0.000
T39.1 4-Aminophenol derivatives	0.278	0.722	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.278	0.722	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.273	0.727	0.000
T42.1 Iminostilbenes	0.272	0.728	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.271	0.729	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.270	0.730	0.000
T40.4 Other synthetic narcotics	0.268	0.732	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.263	0.737	0.000
T38.1 Thyroid hormones and substitutes	0.261	0.739	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.258	0.742	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.256	0.744	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.255	0.745	0.000
T42.2 Succinimides and oxazolidinediones	0.255	0.745	0.000
T38.5 Other oestrogens and progestogens	0.251	0.749	0.000
T43.9 Psychotropic drug, unspecified	0.251	0.749	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.251	0.749	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.250	0.750	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.250	0.750	0.000
T40.5 Cocaine	0.249	0.751	0.000
T43.6 Psychostimulants with abuse potential	0.249	0.751	0.000
T50.1 Loop [high-ceiling] diuretics	0.248	0.752	0.000
T42.3 Barbiturates	0.248	0.752	0.000
T38.0 Glucocorticoids and synthetic analogues	0.246	0.754	0.000
T42.0 Hydantoin derivatives	0.245	0.754	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.243	0.757	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.240	0.760	0.000
T36 Poisoning by systemic antibiotics	0.240	0.760	0.000
T38.9 Other and unspecified hormone antagonists	0.240	0.760	0.000
T38.7 Androgens and anabolic congeners	0.240	0.760	0.000
T38.4 Oral contraceptives	0.240	0.760	0.000
T38.2 Antithyroid drugs	0.240	0.760	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.235	0.765	0.000
T50.8 Diagnostic agents	0.235	0.765	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.229	0.771	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.226	0.774	0.000
T50.7 Analeptics and opioid receptor antagonists	0.226	0.774	0.000
T50.5 Appetite depressants	0.226	0.774	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.226	0.774	0.000
T50.0 Mineralocorticoids and their antagonists	0.226	0.774	0.000
T39.0 Salicylates	0.223	0.777	0.000
T40.1 Heroin	0.218	0.782	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.217	0.783	0.000
T45.2 Vitamins, not elsewhere classified	0.216	0.784	0.000
T39.4 Antirheumatics, not elsewhere classified	0.216	0.784	0.000
T39.2 Pyrazolone derivatives	0.216	0.784	0.000
T45.0 Antiallergic and antiemetic drugs	0.215	0.785	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.215	0.785	0.000
T40.8 Lysergide [LSD]	0.215	0.785	0.000
T40.7 Cannabis (derivatives)	0.215	0.785	0.000
T40.0 Opium	0.215	0.785	0.000
T41.2 Other and unspecified general anaesthetics	0.213	0.787	0.000
T40.3 Methadone	0.212	0.788	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.211	0.789	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.208	0.791	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.200	0.800	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.199	0.801	0.000
T45.8 Other primarily systemic and haematological agents	0.199	0.801	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.199	0.801	0.000
T45.6 Fibrinolysis-affecting drugs	0.199	0.801	0.000
T45.3 Enzymes, not elsewhere classified	0.199	0.801	0.000
T41.5 Therapeutic gases	0.196	0.804	0.000
T41.4 Anaesthetic, unspecified	0.196	0.804	0.000
T41.3 Local anaesthetics	0.196	0.804	0.000
T41.1 Intravenous anaesthetics	0.196	0.804	0.000
T41.0 Inhaled anaesthetics	0.196	0.804	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.196	0.804	0.000
T45.4 Iron and its compounds	0.193	0.807	0.000
T47.6 Antidiarrhoeal drugs	0.193	0.807	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.191	0.809	0.000
T47.2 Stimulant laxatives	0.191	0.809	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.189	0.811	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.189	0.811	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.189	0.811	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.189	0.811	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.189	0.811	0.000
T44.0 Anticholinesterase agents	0.189	0.811	0.000
T40.6 Other and unspecified narcotics	0.188	0.811	0.000
T50.4 Drugs affecting uric acid metabolism	0.187	0.813	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.187	0.813	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.184	0.816	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.184	0.816	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.183	0.817	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.179	0.821	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.179	0.821	0.000
T47.7 Emetics	0.179	0.821	0.000
T47.5 Digestants	0.179	0.821	0.000
T47.3 Saline and osmotic laxatives	0.179	0.821	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.178	0.822	0.000
T36.3 Macrolides	0.177	0.822	0.000
T36.8 Other systemic antibiotics	0.176	0.824	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.174	0.825	0.000
T48.4 Expectorants	0.174	0.825	0.000
T48.3 Antitussives	0.174	0.825	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.174	0.825	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.174	0.825	0.000
T48.0 Oxytocic drugs	0.174	0.825	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.174	0.826	0.000
T49.9 Topical agent, unspecified	0.172	0.827	0.000
T49.8 Other topical agents	0.172	0.827	0.000
T49.7 Dental drugs, topically applied	0.172	0.827	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.172	0.827	0.000
T49.5 Ophthalmological drugs and preparations	0.172	0.827	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.172	0.827	0.000
T49.3 Emollients, demulcents and protectants	0.172	0.827	0.000
T49.2 Local astringents and local detergents	0.172	0.827	0.000
T49.1 Antipruritics	0.172	0.827	0.000
T36.9 Systemic antibiotic, unspecified	0.172	0.828	0.000
T36.7 Antifungal antibiotics, systemically used	0.172	0.828	0.000
T36.6 Rifamycins	0.172	0.828	0.000
T36.5 Aminoglycosides	0.172	0.828	0.000
T36.2 Chloramphenicol group	0.172	0.828	0.000
T48.5 Anti-common-cold drugs	0.170	0.830	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.166	0.834	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.166	0.834	0.000
T47.0 Histamine H(2)-receptor antagonists	0.165	0.835	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.162	0.838	0.000
T37.5 Antiviral drugs	0.162	0.838	0.000
T37.4 Anthelminthics	0.162	0.838	0.000
T37.3 Other antiprotozoal drugs	0.162	0.838	0.000
T37.1 Antimycobacterial drugs	0.162	0.838	0.000
T37.0 Sulphonamides	0.162	0.838	0.000
T36.4 Tetracyclines	0.160	0.840	0.000
T40.2 Other opioids	0.158	0.842	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.156	0.844	0.000
T36.0 Penicillins	0.156	0.844	0.000
T47.4 Other laxatives	0.147	0.853	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.143	0.856	0.000
T45.5 Anticoagulants	0.142	0.857	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.138	0.861	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.138	0.862	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.131	0.868	0.000
T46.7 Peripheral vasodilators	0.131	0.868	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.127	0.872	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.126	0.874	0.001
T46.1 Calcium-channel blockers	0.120	0.880	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.118	0.882	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.115	0.885	0.000
T42.4 Benzodiazepines	0.103	0.897	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.086	0.914	0.000
E53.8 Deficiency of other specified B group vitamins	0.045	0.955	0.000
E53 Deficiency of other B group vitamins	0.022	0.978	0.000
E53.1 Pyridoxine deficiency	0.016	0.984	0.000
E53.0 Riboflavin deficiency	0.016	0.984	0.000
E53.9 Vitamin B deficiency, unspecified	0.016	0.984	0.000
K81.9 Cholecystitis, unspecified	0.010	0.990	0.000
T18.1 Foreign body in oesophagus	0.000	0.991	0.009
M16.0 Primary coxarthrosis, bilateral	0.008	0.992	0.000
E50-E64 Other nutritional deficiencies	0.007	0.993	0.000
D86.9 Sarcoidosis, unspecified	0.007	0.993	0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.006	0.994	0.000
R79.8 Other specified abnormal findings of blood chemistry	0.006	0.994	0.000
E54 Ascorbic acid deficiency	0.005	0.994	0.000
E58 Dietary calcium deficiency	0.005	0.995	0.000
E61 Deficiency of other nutrient elements	0.005	0.995	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.005	0.995	0.000
E50 Vitamin A deficiency	0.005	0.995	0.000
E60 Dietary zinc deficiency	0.005	0.995	0.000
E59 Dietary selenium deficiency	0.005	0.995	0.000
E52 Niacin deficiency [pellagra]	0.005	0.995	0.000
E51 Thiamine deficiency	0.005	0.995	0.000
E63 Other nutritional deficiencies	0.005	0.995	0.000
R20.2 Paraesthesia of skin	0.000	0.995	0.005
D86 Sarcoidosis	0.005	0.995	0.000
E56 Other vitamin deficiencies	0.005	0.995	0.000
D86.0 Sarcoidosis of lung	0.005	0.995	0.000
I67.1 Cerebral aneurysm, nonruptured	0.000	0.995	0.005
C15.5 Lower third of oesophagus	0.000	0.996	0.004
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.004	0.996	0.000
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites	0.000	0.996	0.004
T18 Foreign body in alimentary tract	0.000	0.996	0.004
D86.8 Sarcoidosis of other and combined sites	0.004	0.996	0.000
Z63 Other problems related to primary support group, including family circumstances	0.004	0.996	0.000
C45.0 Mesothelioma of pleura	0.004	0.996	0.000
L85.8 Other specified epidermal thickening	0.000	0.996	0.004
E61.2 Magnesium deficiency	0.004	0.996	0.000
E50.9 Vitamin A deficiency, unspecified	0.004	0.996	0.000
E50.8 Other manifestations of vitamin A deficiency	0.004	0.996	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.004	0.996	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.004	0.996	0.000
E50.5 Vitamin A deficiency with night blindness	0.004	0.996	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.004	0.996	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.004	0.996	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.004	0.996	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.004	0.996	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.004	0.996	0.000
E61.9 Deficiency of nutrient element, unspecified	0.004	0.996	0.000
E61.8 Deficiency of other specified nutrient elements	0.004	0.996	0.000
E61.7 Deficiency of multiple nutrient elements	0.004	0.996	0.000
E61.6 Vanadium deficiency	0.004	0.996	0.000
E61.5 Molybdenum deficiency	0.004	0.996	0.000
E61.4 Chromium deficiency	0.004	0.996	0.000
E61.3 Manganese deficiency	0.004	0.996	0.000
E61.0 Copper deficiency	0.004	0.996	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.004	0.996	0.000
E64.8 Sequelae of other nutritional deficiencies	0.004	0.996	0.000
E64.3 Sequelae of rickets	0.004	0.996	0.000
E64.2 Sequelae of vitamin C deficiency	0.004	0.996	0.000
E64.1 Sequelae of vitamin A deficiency	0.004	0.996	0.000
E64.0 Sequelae of protein-energy malnutrition	0.004	0.996	0.000
E55 Vitamin D deficiency	0.004	0.996	0.000
E51.9 Thiamine deficiency, unspecified	0.004	0.996	0.000
E51.8 Other manifestations of thiamine deficiency	0.004	0.996	0.000
E51.1 Beriberi	0.004	0.996	0.000
Z63.8 Other specified problems related to primary support group	0.004	0.996	0.000
E51.2 Wernicke's encephalopathy	0.004	0.996	0.000
E63.8 Other specified nutritional deficiencies	0.004	0.996	0.000
E63.1 Imbalance of constituents of food intake	0.004	0.996	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.004	0.996	0.000
Z63.5 Disruption of family by separation and divorce	0.004	0.996	0.000
E61.1 Iron deficiency	0.004	0.996	0.000
E63.9 Nutritional deficiency, unspecified	0.004	0.996	0.000
H02.6 Xanthelasma of eyelid	0.004	0.996	0.000
S91.3 Open wound of other parts of foot	0.000	0.996	0.004
C45.7 Mesothelioma of other sites	0.004	0.996	0.000
C45 Mesothelioma	0.004	0.996	0.000
G04 Encephalitis, myelitis and encephalomyelitis	0.004	0.996	0.000
Z63.0 Problems in relationship with spouse or partner	0.004	0.996	0.000
Z59.8 Other problems relating to housing and economic circumstances	0.004	0.996	0.000
T18.0 Foreign body in mouth	0.000	0.996	0.004
C45.9 Mesothelioma, unspecified	0.004	0.996	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.004	0.996	0.000
E56.9 Vitamin deficiency, unspecified	0.003	0.996	0.000
E56.8 Deficiency of other vitamins	0.003	0.996	0.000
E56.0 Deficiency of vitamin E	0.003	0.996	0.000
Z63.7 Other stressful life events affecting family and household	0.004	0.996	0.000
Z59 Problems related to housing and economic circumstances	0.004	0.996	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.004	0.996	0.000
T18.2 Foreign body in stomach	0.000	0.997	0.003
D86.3 Sarcoidosis of skin	0.003	0.997	0.000
O63.0 Prolonged first stage (of labour)	0.003	0.997	0.000
Z57.2 Occupational exposure to dust	0.003	0.997	0.000
T18.8 Foreign body in other and multiple parts of alimentary tract	0.000	0.997	0.003
T18.4 Foreign body in colon	0.000	0.997	0.003
M93.9 Osteochondropathy, unspecified	0.000	0.997	0.003
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.003	0.997	0.000
Z63.9 Problem related to primary support group, unspecified	0.003	0.997	0.000
Z63.4 Disappearance and death of family member	0.003	0.997	0.000
Z63.3 Absence of family member	0.003	0.997	0.000
Z63.2 Inadequate family support	0.003	0.997	0.000
Z63.1 Problems in relationship with parents and in-laws	0.003	0.997	0.000
T18.9 Foreign body in alimentary tract, part unspecified	0.000	0.997	0.003
E55.0 Rickets, active	0.003	0.997	0.000
T18.3 Foreign body in small intestine	0.000	0.997	0.003
E56.1 Deficiency of vitamin K	0.003	0.997	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.000	0.997	0.003
Z59.9 Problem relating to housing and economic circumstances, unspecified	0.003	0.997	0.000
G04.0 Acute disseminated encephalitis	0.003	0.997	0.000
C45.2 Mesothelioma of pericardium	0.003	0.997	0.000
C45.1 Mesothelioma of peritoneum	0.003	0.997	0.000
G04.8 Other encephalitis, myelitis and encephalomyelitis	0.003	0.997	0.000
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified	0.003	0.997	0.000
G04.1 Tropical spastic paraplegia	0.003	0.997	0.000
K11.2 Sialoadenitis	0.003	0.997	0.000
R79.9 Abnormal finding of blood chemistry, unspecified	0.003	0.997	0.000
Z59.1 Inadequate housing	0.003	0.997	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.003	0.997	0.000
Z61 Problems related to negative life events in childhood	0.003	0.997	0.000
K55.2 Angiodysplasia of colon	0.000	0.997	0.003
R82.9 Other and unspecified abnormal finding in urine	0.003	0.997	0.000
Z57 Occupational exposure to risk-factors	0.003	0.997	0.000
L29.9 Pruritus, unspecified	0.003	0.997	0.000
Z63.6 Dependent relative needing care at home	0.003	0.997	0.000
Z65 Problems related to other psychosocial circumstances	0.003	0.997	0.000
R79 Other abnormal findings of blood chemistry	0.003	0.997	0.000
S91 Open wound of ankle and foot	0.000	0.997	0.003
D86.1 Sarcoidosis of lymph nodes	0.003	0.997	0.000
Z59.7 Insufficient social insurance and welfare support	0.003	0.997	0.000
Z59.6 Low income	0.003	0.997	0.000
Z59.5 Extreme poverty	0.003	0.997	0.000
Z59.3 Problems related to living in residential institution	0.003	0.997	0.000
Z56 Problems related to employment and unemployment	0.003	0.997	0.000
Z59.0 Homelessness	0.003	0.997	0.000
O63.1 Prolonged second stage (of labour)	0.003	0.997	0.000
L85 Other epidermal thickening	0.000	0.997	0.003
Z59.4 Lack of adequate food	0.003	0.997	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.000	0.997	0.003
T18.5 Foreign body in anus and rectum	0.000	0.997	0.002
Z58 Problems related to physical environment	0.003	0.997	0.000
I84.0 Internal thrombosed haemorrhoids	0.003	0.997	0.000
Z59.2 Discord with neighbours, lodgers and landlord	0.002	0.997	0.000
L85.1 Acquired keratosis [keratoderma] palmaris et plantaris	0.000	0.997	0.003
Z62 Other problems related to upbringing	0.003	0.997	0.000
Z55 Problems related to education and literacy	0.003	0.997	0.000
R20.0 Anaesthesia of skin	0.000	0.997	0.003
I67.2 Cerebral atherosclerosis	0.000	0.997	0.003
S91.0 Open wound of ankle	0.000	0.997	0.003
Z61.4 Problems related to alleged sexual abuse of child by person within primary support group	0.002	0.997	0.000
Z56.6 Other physical and mental strain related to work	0.003	0.997	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.002	0.997	0.000
I67 Other cerebrovascular diseases	0.000	0.997	0.003
L85.9 Epidermal thickening, unspecified	0.000	0.997	0.003
S91.2 Open wound of toe(s) with damage to nail	0.000	0.997	0.002
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.002	0.997	0.000
D80-D89 Certain disorders involving the immune mechanism	0.002	0.997	0.000
K01.1 Impacted teeth	0.003	0.997	0.000
Z61.6 Problems related to alleged physical abuse of child	0.002	0.997	0.000
N92.3 Ovulation bleeding	0.000	0.998	0.002
Z61.5 Problems related to alleged sexual abuse of child by person outside primary support group	0.002	0.998	0.000
Z65.9 Problem related to unspecified psychosocial circumstances	0.002	0.998	0.000
D89.3 Immune reconstitution syndrome	0.002	0.998	0.000
Z56.7 Other and unspecified problems related to employment	0.002	0.998	0.000
Z56.4 Discord with boss and workmates	0.002	0.998	0.000
Z61.8 Other negative life events in childhood	0.002	0.998	0.000
Z65.3 Problems related to other legal circumstances	0.002	0.998	0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
Z61.9 Negative life events in childhood, unspecified	0.002	0.998	0.000
Z61.7 Personal frightening experience in childhood	0.002	0.998	0.000
Z61.3 Events resulting in loss of self-esteem in childhood	0.002	0.998	0.000
Z61.2 Altered pattern of family relationships in childhood	0.002	0.998	0.000
Z61.1 Removal from home in childhood	0.002	0.998	0.000
Z61.0 Loss of love relationship in childhood	0.002	0.998	0.000
S27.0 Traumatic pneumothorax	0.000	0.998	0.002
Z58.5 Exposure to other pollution	0.002	0.998	0.000
O63 Long labour	0.002	0.998	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
R40.0 Somnolence	0.002	0.998	0.000
Z57.9 Occupational exposure to unspecified risk-factor	0.002	0.998	0.000
Z57.7 Occupational exposure to vibration	0.002	0.998	0.000
Z57.6 Occupational exposure to extreme temperature	0.002	0.998	0.000
Z57.4 Occupational exposure to toxic agents in agriculture	0.002	0.998	0.000
Z57.1 Occupational exposure to radiation	0.002	0.998	0.000
Z57.0 Occupational exposure to noise	0.002	0.998	0.000
Z65.8 Other specified problems related to psychosocial circumstances	0.002	0.998	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.000	0.998	0.002
Z57.8 Occupational exposure to other risk-factors	0.002	0.998	0.000
Z65.5 Exposure to disaster, war and other hostilities	0.002	0.998	0.000
Z65.4 Victim of crime and terrorism	0.002	0.998	0.000
Z65.2 Problems related to release from prison	0.002	0.998	0.000
Z65.1 Imprisonment and other incarceration	0.002	0.998	0.000
Z65.0 Conviction in civil and criminal proceedings without imprisonment	0.002	0.998	0.000
S91.7 Multiple open wounds of ankle and foot	0.000	0.998	0.002
Z56.5 Uncongenial work	0.002	0.998	0.000
Z56.2 Threat of job loss	0.002	0.998	0.000
Z56.1 Change of job	0.002	0.998	0.000
Z64 Problems related to certain psychosocial circumstances	0.002	0.998	0.000
L85.3 Xerosis cutis	0.000	0.998	0.002
L85.2 Keratosis punctata (palmaris et plantaris)	0.000	0.998	0.002
L85.0 Acquired ichthyosis	0.000	0.998	0.002
R20 Disturbances of skin sensation	0.000	0.998	0.002
D89.1 Cryoglobulinaemia	0.002	0.998	0.000
Z58.1 Exposure to air pollution	0.002	0.998	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.002	0.998	0.000
S91.1 Open wound of toe(s) without damage to nail	0.000	0.998	0.002
Z58.9 Problem related to physical environment, unspecified	0.002	0.998	0.000
Z58.6 Inadequate drinking-water supply	0.002	0.998	0.000
Z58.4 Exposure to radiation	0.002	0.998	0.000
Z58.3 Exposure to soil pollution	0.002	0.998	0.000
Z58.2 Exposure to water pollution	0.002	0.998	0.000
Z58.0 Exposure to noise	0.002	0.998	0.000
C67.6 Ureteric orifice	0.002	0.998	0.000
K13.0 Diseases of lips	0.000	0.998	0.002
Q82.8 Other specified congenital malformations of skin	0.000	0.998	0.002
Z56.0 Unemployment, unspecified	0.002	0.998	0.000
M99.53 Intervertebral disc stenosis of neural canal (Lumbar region)	0.000	0.998	0.002
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.000	0.998	0.002
Z55.9 Problems relating to education and literacy, unspecified	0.002	0.998	0.000
Z55.8 Other problems relating to education and literacy	0.002	0.998	0.000
Z55.4 Educational maladjustment and discord with teachers and classmates	0.002	0.998	0.000
Z55.3 Underachievement in school	0.002	0.998	0.000
Z55.2 Failed examinations	0.002	0.998	0.000
Z55.1 Schooling unavailable and unattainable	0.002	0.998	0.000
Z55.0 Illiteracy and low-level literacy	0.002	0.998	0.000
Z62.9 Problem related to upbringing, unspecified	0.002	0.998	0.000
Z62.8 Other specified problems related to upbringing	0.002	0.998	0.000
Z62.6 Inappropriate parental pressure and other abnormal qualities of upbringing	0.002	0.998	0.000
Z62.5 Other problems related to neglect in upbringing	0.002	0.998	0.000
Z62.4 Emotional neglect of child	0.002	0.998	0.000
Z62.3 Hostility towards and scapegoating of child	0.002	0.998	0.000
Z62.2 Institutional upbringing	0.002	0.998	0.000
Z62.1 Parental overprotection	0.002	0.998	0.000
Z62.0 Inadequate parental supervision and control	0.002	0.998	0.000
Z58.7 Exposure to tobacco smoke	0.002	0.998	0.000
D82 Immunodeficiency associated with other major defects	0.002	0.998	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.000	0.998	0.002
I67.5 Moyamoya disease	0.000	0.998	0.002
I67.3 Progressive vascular leukoencephalopathy	0.000	0.998	0.002
Z58.8 Other problems related to physical environment	0.002	0.998	0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.002	0.998	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
S22.40 Multiple fractures of ribs (closed)	0.000	0.998	0.002
I67.4 Hypertensive encephalopathy	0.000	0.998	0.002
D81 Combined immunodeficiencies	0.002	0.998	0.000
G90.2 Horner's syndrome	0.002	0.998	0.000
Z56.3 Stressful work schedule	0.002	0.998	0.000
G24.9 Dystonia, unspecified	0.002	0.998	0.000
R40.1 Stupor	0.002	0.998	0.000
O34.2 Maternal care due to uterine scar from previous surgery	0.002	0.998	0.000
L29 Pruritus	0.002	0.998	0.000
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere	0.002	0.998	0.000
Y84.8 Other medical procedures	0.002	0.998	0.000
O63.2 Delayed delivery of second twin, triplet, etc.	0.002	0.998	0.000
D83 Common variable immunodeficiency	0.002	0.998	0.000
R20.3 Hyperaesthesia	0.000	0.998	0.002
Z57.3 Occupational exposure to other air contaminants	0.002	0.998	0.000
M93 Other osteochondropathies	0.000	0.998	0.002
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.000	0.998	0.002
L29.2 Pruritus vulvae	0.002	0.998	0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.002	0.998	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.002	0.998	0.000
R40.2 Coma, unspecified	0.002	0.998	0.000
Z64.4 Discord with counsellors	0.002	0.998	0.000
Z64.3 Seeking and accepting behavioural and psychological interventions known to be hazardous and harmful	0.002	0.998	0.000
Z64.2 Seeking and accepting physical, nutritional and chemical interventions known to be hazardous and harmful	0.002	0.998	0.000
Z64.1 Problems related to multiparity	0.002	0.998	0.000
R40 Somnolence, stupor and coma	0.002	0.998	0.000
M87.98 Osteonecrosis, unspecified (Other)	0.000	0.998	0.002
G90.0 Idiopathic peripheral autonomic neuropathy	0.002	0.998	0.000
R82.8 Abnormal findings on cytological and histological examination of urine	0.002	0.998	0.000
S27 Injury of other and unspecified intrathoracic organs	0.000	0.998	0.002
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.000	0.998	0.002
U89.8 Agent resistant to other single specified antibiotic	0.000	0.998	0.002
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.002	0.998	0.000
E55.9 Vitamin D deficiency, unspecified	0.002	0.998	0.000
G90.9 Disorder of autonomic nervous system, unspecified	0.002	0.998	0.000
M95.4 Acquired deformity of chest and rib	0.000	0.998	0.002
R20.1 Hypoaesthesia of skin	0.000	0.998	0.002
S27.1 Traumatic haemothorax	0.000	0.998	0.002
J15.2 Pneumonia due to staphylococcus	0.002	0.998	0.000
L29.3 Anogenital pruritus, unspecified	0.002	0.998	0.000
M87.9 Osteonecrosis, unspecified	0.000	0.998	0.002
O75.2 Pyrexia during labour, not elsewhere classified	0.002	0.998	0.000
D84 Other immunodeficiencies	0.002	0.998	0.000
I87.1 Compression of vein	0.000	0.998	0.002
L20.9 Atopic dermatitis, unspecified	0.002	0.998	0.000
L29.0 Pruritus ani	0.002	0.998	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.000	0.998	0.002
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
R82 Other abnormal findings in urine	0.002	0.998	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.002	0.998	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.002	0.998	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.002	0.998	0.000
D82.2 Immunodeficiency with short-limbed stature	0.002	0.998	0.000
D82.1 Di George's syndrome	0.002	0.998	0.000
D82.0 Wiskott-Aldrich syndrome	0.002	0.998	0.000
S30.0 Contusion of lower back and pelvis	0.000	0.998	0.002
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.002	0.998	0.000
S27.3 Other injuries of lung	0.000	0.998	0.002
M95.2 Other acquired deformity of head	0.000	0.998	0.002
R44.1 Visual hallucinations	0.002	0.998	0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.000	0.998	0.002
D81.9 Combined immunodeficiency, unspecified	0.002	0.998	0.000
D81.8 Other combined immunodeficiencies	0.002	0.998	0.000
D81.7 Major histocompatibility complex class II deficiency	0.002	0.998	0.000
D81.6 Major histocompatibility complex class I deficiency	0.002	0.998	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.002	0.998	0.000
D81.4 Nezelof's syndrome	0.002	0.998	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.002	0.998	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.002	0.998	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.002	0.998	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.002	0.998	0.000
C15 Malignant neoplasm of oesophagus	0.000	0.998	0.002
G90 Disorders of autonomic nervous system	0.002	0.998	0.000
M99.5 Intervertebral disk stenosis of neural canal	0.000	0.998	0.002
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.000	0.998	0.002
L29.1 Pruritus scroti	0.002	0.998	0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.000	0.998	0.002
G95.2 Cord compression, unspecified	0.002	0.998	0.000
G01 Meningitis in bacterial diseases classified elsewhere	0.002	0.998	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.002	0.998	0.000
C15.4 Middle third of oesophagus	0.000	0.998	0.002
C67.2 Lateral wall of bladder	0.002	0.998	0.000
D83.8 Other common variable immunodeficiencies	0.001	0.998	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.001	0.998	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.001	0.998	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.001	0.998	0.000
F45.8 Other somatoform disorders	0.002	0.998	0.000
S30.1 Contusion of abdominal wall	0.000	0.998	0.002
S30 Superficial injury of abdomen, lower back and pelvis	0.000	0.998	0.002
M93.8 Other specified osteochondropathies	0.000	0.998	0.002
M93.2 Osteochondritis dissecans	0.000	0.998	0.002
M93.1 Kienbock's disease of adults	0.000	0.998	0.002
M93.0 Slipped upper femoral epiphysis (nontraumatic)	0.000	0.998	0.002
M95.3 Acquired deformity of neck	0.000	0.998	0.002
C32.0 Glottis	0.000	0.998	0.002
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere	0.001	0.998	0.000
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere	0.001	0.998	0.000
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere	0.001	0.998	0.000
I08.0 Disorders of both mitral and aortic valves	0.000	0.998	0.002
O34.5 Maternal care for other abnormalities of gravid uterus	0.002	0.998	0.000
O34.4 Maternal care for other abnormalities of cervix	0.002	0.998	0.000
V89.2 Person injured in unspecified motor-vehicle accident, traffic	0.000	0.998	0.002
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.002	0.998	0.000
R82.1 Myoglobinuria	0.002	0.998	0.000
S27.2 Traumatic heamopneumothorax	0.000	0.998	0.002
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations