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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7248104
log Bayes Factor = 1.00902
Chromosome 19   position 7,224,431  (GRCh37) Explore rs7248104 on Ensembl!
Variant rs7248104 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E04.2 Non-toxic multinodular goitre
0.870 0.130 0.000
E04 Other non-toxic goitre
0.784 0.216 0.000
E04.9 Non-toxic goitre, unspecified
0.768 0.232 0.000
E04.8 Other specified non-toxic goitre
0.562 0.438 0.000
E04.0 Non-toxic diffuse goitre
0.557 0.443 0.000
E04.1 Non-toxic single thyroid nodule
0.534 0.466 0.000
E78.0 Pure hypercholesterolaemia
0.000 0.866 0.134
O80.0 Spontaneous vertex delivery
0.127 0.873 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.000 0.899 0.101
D60-D64 Aplastic and other anaemias
0.000 0.900 0.100
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.900 0.100
O80 Single spontaneous delivery
0.098 0.902 0.000
D62 Acute posthaemorrhagic anaemia
0.000 0.902 0.098
D64 Other anaemias
0.000 0.903 0.097
D64.9 Anaemia, unspecified
0.000 0.905 0.095
E03.9 Hypothyroidism, unspecified
0.000 0.910 0.090
E00-E07 Disorders of thyroid gland
0.082 0.913 0.004
O80.9 Single spontaneous delivery, unspecified
0.086 0.914 0.000
E03 Other hypothyroidism
0.014 0.917 0.069
O80.8 Other single spontaneous delivery
0.072 0.927 0.000
E06 Thyroiditis
0.071 0.928 0.001
D63.1 Anaemia in other chronic diseases classified elsewhere
0.000 0.928 0.072
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.928 0.072
O80.1 Spontaneous breech delivery
0.070 0.930 0.000
D63.0 Anaemia in neoplastic disease
0.000 0.930 0.070
D64.4 Congenital dyserythropoietic anaemia
0.000 0.930 0.069
D64.3 Other sideroblastic anaemias
0.000 0.930 0.069
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.930 0.069
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.930 0.069
D64.0 Hereditary sideroblastic anaemia
0.000 0.930 0.069
D64.8 Other specified anaemias
0.000 0.931 0.069
E03.8 Other specified hypothyroidism
0.004 0.931 0.066
E02 Subclinical iodine-deficiency hypothyroidism
0.061 0.936 0.003
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.059 0.938 0.003
E00 Congenital iodine-deficiency syndrome
0.059 0.938 0.003
E03.5 Myxoedema coma
0.010 0.940 0.050
E03.4 Atrophy of thyroid (acquired)
0.010 0.940 0.050
E03.3 Postinfectious hypothyroidism
0.010 0.940 0.050
E03.1 Congenital hypothyroidism without goitre
0.010 0.940 0.050
E03.0 Congenital hypothyroidism with diffuse goitre
0.010 0.940 0.050
E06.1 Subacute thyroiditis
0.059 0.941 0.001
E06.9 Thyroiditis, unspecified
0.059 0.941 0.001
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.009 0.943 0.048
D86 Sarcoidosis
0.000 0.944 0.056
D86.9 Sarcoidosis, unspecified
0.000 0.945 0.055
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.948 0.052
E06.4 Drug-induced thyroiditis
0.051 0.948 0.001
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.051 0.948 0.001
E06.0 Acute thyroiditis
0.051 0.948 0.001
D60.8 Other acquired pure red cell aplasias
0.000 0.948 0.051
D60.1 Transient acquired pure red cell aplasia
0.000 0.948 0.051
D60.0 Chronic acquired pure red cell aplasia
0.000 0.948 0.051
D60.9 Acquired pure red cell aplasia, unspecified
0.000 0.948 0.051
D80-D89 Certain disorders involving the immune mechanism
0.000 0.949 0.051
E06.5 Other chronic thyroiditis
0.050 0.949 0.001
D86.0 Sarcoidosis of lung
0.000 0.950 0.050
D61 Other aplastic anaemias
0.000 0.950 0.050
E06.3 Autoimmune thyroiditis
0.049 0.950 0.000
D86.1 Sarcoidosis of lymph nodes
0.000 0.951 0.049
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.952 0.048
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.042 0.955 0.002
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.042 0.955 0.002
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.042 0.955 0.002
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.042 0.955 0.002
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.042 0.955 0.002
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.042 0.955 0.002
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.042 0.955 0.002
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.042 0.955 0.002
E78.2 Mixed hyperlipidaemia
0.000 0.955 0.045
D86.8 Sarcoidosis of other and combined sites
0.000 0.956 0.044
O80-O84 Delivery
0.043 0.957 0.000
E07 Other disorders of thyroid
0.040 0.957 0.003
E78.4 Other hyperlipidaemia
0.000 0.957 0.043
D80 Immunodeficiency with predominantly antibody defects
0.000 0.958 0.042
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.958 0.042
E78.1 Pure hyperglyceridaemia
0.000 0.960 0.040
D86.3 Sarcoidosis of skin
0.000 0.960 0.040
E78.6 Lipoprotein deficiency
0.000 0.961 0.039
D82 Immunodeficiency associated with other major defects
0.000 0.961 0.039
D83 Common variable immunodeficiency
0.000 0.963 0.037
D81 Combined immunodeficiencies
0.000 0.963 0.037
D61.1 Drug-induced aplastic anaemia
0.000 0.963 0.036
D61.0 Constitutional aplastic anaemia
0.000 0.964 0.036
D61.8 Other specified aplastic anaemias
0.000 0.964 0.036
D61.3 Idiopathic aplastic anaemia
0.000 0.964 0.036
D61.2 Aplastic anaemia due to other external agents
0.000 0.964 0.036
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.000 0.964 0.036
D55-D59 Haemolytic anaemias
0.000 0.964 0.036
D84 Other immunodeficiencies
0.000 0.965 0.035
O83 Other assisted single delivery
0.034 0.966 0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.000 0.966 0.034
O81 Single delivery by forceps and vacuum extractor
0.033 0.967 0.000
E78.3 Hyperchylomicronaemia
0.000 0.967 0.033
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.968 0.032
E07.8 Other specified disorders of thyroid
0.030 0.968 0.002
O84 Multiple delivery
0.031 0.969 0.000
E07.1 Dyshormogenetic goitre
0.029 0.969 0.002
E07.0 Hypersecretion of calcitonin
0.029 0.969 0.002
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.000 0.969 0.031
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.970 0.030
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.970 0.030
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.000 0.970 0.030
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.970 0.030
D80.0 Hereditary hypogammaglobulinaemia
0.000 0.970 0.030
D82.1 Di George's syndrome
0.000 0.970 0.030
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.000 0.970 0.030
E78.8 Other disorders of lipoprotein metabolism
0.000 0.971 0.029
D82.9 Immunodeficiency associated with major defect, unspecified
0.000 0.972 0.028
D82.8 Immunodeficiency associated with other specified major defects
0.000 0.972 0.028
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.000 0.972 0.028
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.000 0.972 0.028
D82.2 Immunodeficiency with short-limbed stature
0.000 0.972 0.028
D82.0 Wiskott-Aldrich syndrome
0.000 0.972 0.028
D58 Other hereditary haemolytic anaemias
0.000 0.972 0.028
O83.1 Other assisted breech delivery
0.027 0.973 0.000
O82 Single delivery by Caesarean section
0.027 0.973 0.000
D83.9 Common variable immunodeficiency, unspecified
0.000 0.973 0.027
D83.8 Other common variable immunodeficiencies
0.000 0.973 0.026
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.000 0.973 0.026
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.000 0.973 0.026
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.000 0.973 0.026
D81.9 Combined immunodeficiency, unspecified
0.000 0.973 0.026
D81.8 Other combined immunodeficiencies
0.000 0.973 0.026
D81.7 Major histocompatibility complex class II deficiency
0.000 0.973 0.026
D81.6 Major histocompatibility complex class I deficiency
0.000 0.973 0.026
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.000 0.973 0.026
D81.4 Nezelof's syndrome
0.000 0.973 0.026
D81.3 Adenosine deaminase [ADA] deficiency
0.000 0.973 0.026
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.000 0.973 0.026
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.000 0.973 0.026
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.000 0.973 0.026
O81.0 Low forceps delivery
0.026 0.973 0.000
D84.9 Immunodeficiency, unspecified
0.000 0.974 0.026
D55 Anaemia due to enzyme disorders
0.000 0.974 0.026
D57 Sickle-cell disorders
0.000 0.974 0.026
D59 Acquired haemolytic anaemia
0.000 0.974 0.025
D80.1 Nonfamilial hypogammaglobulinaemia
0.000 0.975 0.025
D84.1 Defects in the complement system
0.000 0.975 0.025
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.000 0.975 0.025
D56 Thalassaemia
0.000 0.975 0.025
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.975 0.025
O83.9 Assisted single delivery, unspecified
0.025 0.975 0.000
O83.8 Other specified assisted single delivery
0.025 0.975 0.000
O83.4 Destructive operation for delivery
0.025 0.975 0.000
O83.3 Delivery of viable foetus in abdominal pregnancy
0.025 0.975 0.000
O83.2 Other manipulation-assisted delivery
0.025 0.975 0.000
O83.0 Breech extraction
0.025 0.975 0.000
D58.9 Hereditary haemolytic anaemia, unspecified
0.000 0.976 0.024
O81.5 Delivery by combination of forceps and vacuum extractor
0.024 0.976 0.000
O81.2 Mid-cavity forceps with rotation
0.024 0.976 0.000
O81.1 Mid-cavity forceps delivery
0.024 0.976 0.000
O81.3 Other and unspecified forceps delivery
0.024 0.976 0.000
E78.5 Hyperlipidaemia, unspecified
0.000 0.977 0.023
O81.4 Vacuum extractor delivery
0.023 0.977 0.000
O84.9 Multiple delivery, unspecified
0.023 0.977 0.000
O84.8 Other multiple delivery
0.023 0.977 0.000
O84.2 Multiple delivery, all by Caesarean section
0.023 0.977 0.000
O84.1 Multiple delivery, all by forceps and vacuum extractor
0.023 0.977 0.000
O84.0 Multiple delivery, all spontaneous
0.023 0.977 0.000
O82.9 Delivery by Caesarean section, unspecified
0.022 0.978 0.000
K60.3 Anal fistula
0.021 0.979 0.000
D84.8 Other specified immunodeficiencies
0.000 0.979 0.021
K60 Fissure and fistula of anal and rectal regions
0.021 0.979 0.000
K60.2 Anal fissure, unspecified
0.021 0.979 0.000
D58.8 Other specified hereditary haemolytic anaemias
0.000 0.980 0.020
D58.1 Hereditary elliptocytosis
0.000 0.980 0.020
O82.8 Other single delivery by Caesarean section
0.020 0.980 0.000
O82.2 Delivery by Caesarean hysterectomy
0.020 0.980 0.000
D59.9 Acquired haemolytic anaemia, unspecified
0.000 0.981 0.019
D58.0 Hereditary spherocytosis
0.000 0.981 0.019
K60.4 Rectal fistula
0.019 0.981 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.018 0.981 0.001
G93.3 Postviral fatigue syndrome
0.000 0.981 0.019
D55.9 Anaemia due to enzyme disorder, unspecified
0.000 0.981 0.019
D55.8 Other anaemias due to enzyme disorders
0.000 0.981 0.019
D55.3 Anaemia due to disorders of nucleotide metabolism
0.000 0.981 0.019
D55.2 Anaemia due to disorders of glycolytic enzymes
0.000 0.981 0.019
D55.1 Anaemia due to other disorders of glutathione metabolism
0.000 0.981 0.019
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency
0.000 0.981 0.019
D57.8 Other sickle-cell disorders
0.000 0.981 0.018
D57.3 Sickle-cell trait
0.000 0.981 0.018
D57.2 Double heterozygous sickling disorders
0.000 0.981 0.018
D57.0 Sickle-cell anaemia with crisis
0.000 0.981 0.018
D59.8 Other acquired haemolytic anaemias
0.000 0.981 0.018
D59.6 Haemoglobinuria due to haemolysis from other external causes
0.000 0.981 0.018
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]
0.000 0.981 0.018
D59.4 Other nonautoimmune haemolytic anaemias
0.000 0.981 0.018
D59.3 Haemolytic-uraemic syndrome
0.000 0.981 0.018
D59.2 Drug-induced nonautoimmune haemolytic anaemia
0.000 0.981 0.018
D57.1 Sickle-cell anaemia without crisis
0.000 0.982 0.018
D56.1 Beta thalassaemia
0.000 0.982 0.018
K60.0 Acute anal fissure
0.018 0.982 0.000
D56.9 Thalassaemia, unspecified
0.000 0.982 0.018
D56.8 Other thalassaemias
0.000 0.982 0.018
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]
0.000 0.982 0.018
D56.2 Delta-beta thalassaemia
0.000 0.982 0.018
D56.0 Alpha thalassaemia
0.000 0.982 0.018
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.000 0.982 0.018
D89.3 Immune reconstitution syndrome
0.000 0.982 0.018
D58.2 Other haemoglobinopathies
0.000 0.982 0.018
D59.0 Drug-induced autoimmune haemolytic anaemia
0.000 0.982 0.018
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.982 0.018
D59.1 Other autoimmune haemolytic anaemias
0.000 0.982 0.018
D89.0 Polyclonal hypergammaglobulinaemia
0.000 0.983 0.017
D56.3 Thalassaemia trait
0.000 0.983 0.017
O82.1 Delivery by emergency Caesarean section
0.016 0.984 0.000
D06.9 Cervix, unspecified
0.000 0.984 0.016
O82.0 Delivery by elective Caesarean section
0.016 0.984 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.984 0.016
K60.1 Chronic anal fissure
0.015 0.985 0.000
D89.2 Hypergammaglobulinaemia, unspecified
0.000 0.985 0.015
K60.5 Anorectal fistula
0.015 0.985 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.013 0.986 0.001
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.014 0.986 0.001
D66 Hereditary factor VIII deficiency
0.000 0.986 0.014
D89.1 Cryoglobulinaemia
0.000 0.986 0.014
E05.5 Thyroid crisis or storm
0.013 0.986 0.001
E05.4 Thyrotoxicosis factitia
0.013 0.986 0.001
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.013 0.986 0.001
I10 Essential (primary) hypertension
0.000 0.987 0.013
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.987 0.013
E05.8 Other thyrotoxicosis
0.011 0.988 0.001
D67 Hereditary factor IX deficiency
0.000 0.988 0.012
D61.9 Aplastic anaemia, unspecified
0.000 0.988 0.012
D75.8 Other specified diseases of blood and blood-forming organs
0.000 0.988 0.012
D75 Other diseases of blood and blood-forming organs
0.000 0.989 0.011
D50-D53 Nutritional anaemias
0.000 0.990 0.010
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.990 0.010
D74 Methaemoglobinaemia
0.000 0.990 0.010
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.000 0.990 0.010
D71 Functional disorders of polymorphonuclear neutrophils
0.000 0.990 0.010
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.000 0.990 0.010
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.000 0.990 0.009
D75.9 Disease of blood and blood-forming organs, unspecified
0.000 0.991 0.009
E07.9 Disorder of thyroid, unspecified
0.007 0.991 0.003
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.009 0.991 0.000
A49.9 Bacterial infection, unspecified
0.008 0.992 0.000
S52.00 Fracture of upper end of ulna (closed)
0.000 0.992 0.008
D72 Other disorders of white blood cells
0.000 0.992 0.008
D75.0 Familial erythrocytosis
0.000 0.992 0.008
M13.94 Arthritis, unspecified (Hand)
0.008 0.992 0.000
S92.30 Fracture of metatarsal bone (closed)
0.000 0.992 0.008
K57.3 Diverticular disease of large intestine without perforation or abscess
0.000 0.992 0.008
A49.8 Other bacterial infections of unspecified site
0.007 0.993 0.000
D74.9 Methaemoglobinaemia, unspecified
0.000 0.993 0.007
D74.8 Other methaemoglobinaemias
0.000 0.993 0.007
D74.0 Congenital methaemoglobinaemia
0.000 0.993 0.007
D53 Other nutritional anaemias
0.000 0.993 0.007
D76.2 Haemophagocytic syndrome, infection-associated
0.000 0.993 0.007
D76.1 Haemophagocytic lymphohistiocytosis
0.000 0.993 0.007
D76.0 Langerhans' cell histiocytosis, not elsewhere classified
0.000 0.993 0.007
A49 Bacterial infection of unspecified site
0.007 0.993 0.000
D76.3 Other histiocytosis syndromes
0.000 0.993 0.007
D75.2 Essential thrombocytosis
0.000 0.993 0.007
M06.0 Seronegative rheumatoid arthritis
0.007 0.993 0.000
A49.1 Streptococcal infection, unspecified
0.006 0.994 0.000
D52 Folate deficiency anaemia
0.000 0.994 0.006
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.000 0.994 0.006
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.000 0.994 0.006
D72.9 Disorder of white blood cells, unspecified
0.000 0.994 0.006
D72.0 Genetic anomalies of leukocytes
0.000 0.994 0.006
D72.1 Eosinophilia
0.000 0.994 0.006
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.006 0.994 0.000
D06 Carcinoma in situ of cervix uteri
0.000 0.994 0.006
S52.0 Fracture of upper end of ulna
0.000 0.994 0.006
R59.0 Localised enlarged lymph nodes
0.000 0.994 0.006
M06.04 Seronegative rheumatoid arthritis (Hand)
0.006 0.994 0.000
A49.0 Staphylococcal infection, unspecified
0.006 0.994 0.000
H53.8 Other visual disturbances
0.006 0.994 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.005 0.995 0.000
D51 Vitamin B12 deficiency anaemia
0.000 0.995 0.005
D53.8 Other specified nutritional anaemias
0.000 0.995 0.005
D53.2 Scorbutic anaemia
0.000 0.995 0.005
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.000 0.995 0.005
D53.0 Protein deficiency anaemia
0.000 0.995 0.005
R59.1 Generalised enlarged lymph nodes
0.000 0.995 0.005
A49.3 Mycoplasma infection, unspecified
0.005 0.995 0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.005 0.995 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.005 0.995 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.005 0.995 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.005 0.995 0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.005 0.995 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.005 0.995 0.000
A49.2 Haemophilus influenzae infection, unspecified
0.005 0.995 0.000
S92.3 Fracture of metatarsal bone
0.000 0.995 0.005
S52.01 Fracture of upper end of ulna (open)
0.000 0.995 0.005
D53.9 Nutritional anaemia, unspecified
0.000 0.995 0.004
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.995 0.005
R59 Enlarged lymph nodes
0.000 0.995 0.005
D52.8 Other folate deficiency anaemias
0.000 0.995 0.004
D52.1 Drug-induced folate deficiency anaemia
0.000 0.995 0.004
D52.0 Dietary folate deficiency anaemia
0.000 0.995 0.004
D73 Diseases of spleen
0.000 0.995 0.005
D06.7 Other parts of cervix
0.000 0.995 0.004
D06.1 Exocervix
0.000 0.996 0.004
S32.50 Fracture of pubis (closed)
0.000 0.996 0.004
Z52.4 Kidney donor
0.004 0.996 0.000
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.996 0.004
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.996 0.004
D51.2 Transcobalamin II deficiency
0.000 0.996 0.004
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.996 0.004
S61.8 Open wound of other parts of wrist and hand
0.000 0.996 0.004
D72.8 Other specified disorders of white blood cells
0.000 0.996 0.004
G24.9 Dystonia, unspecified
0.004 0.996 0.000
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge
0.000 0.996 0.004
Z50.2 Alcohol rehabilitation
0.000 0.996 0.004
D06.0 Endocervix
0.000 0.996 0.004
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.004 0.996 0.000
I21.4 Acute subendocardial myocardial infarction
0.000 0.996 0.004
R57.2 Septic shock
0.000 0.996 0.004
E88 Other metabolic disorders
0.000 0.996 0.004
S92.31 Fracture of metatarsal bone (open)
0.000 0.996 0.004
S52 Fracture of forearm
0.000 0.996 0.004
D73.8 Other diseases of spleen
0.000 0.996 0.004
D73.3 Abscess of spleen
0.000 0.996 0.004
E05.0 Thyrotoxicosis with diffuse goitre
0.003 0.996 0.001
D73.2 Chronic congestive splenomegaly
0.000 0.996 0.003
S52.2 Fracture of shaft of ulna
0.000 0.996 0.004
D73.1 Hypersplenism
0.000 0.996 0.003
D73.9 Disease of spleen, unspecified
0.000 0.996 0.003
R59.9 Enlarged lymph nodes, unspecified
0.000 0.996 0.003
S52.20 Fracture of shaft of ulna (closed)
0.000 0.997 0.003
H74.9 Disorder of middle ear and mastoid, unspecified
0.000 0.997 0.003
D73.4 Cyst of spleen
0.000 0.997 0.003
S91.3 Open wound of other parts of foot
0.000 0.997 0.003
G24 Dystonia
0.003 0.997 0.000
R57.0 Cardiogenic shock
0.000 0.997 0.003
S52.6 Fracture of lower end of both ulna and radius
0.000 0.997 0.003
S52.3 Fracture of shaft of radius
0.000 0.997 0.003
D75.1 Secondary polycythaemia
0.000 0.997 0.003
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.997 0.003
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.997 0.003
E88.3 Tumour lysis syndrome
0.000 0.997 0.003
G24.3 Spasmodic torticollis
0.003 0.997 0.000
S52.7 Multiple fractures of forearm
0.000 0.997 0.003
S52.61 Fracture of lower end of both ulna and radius (open)
0.000 0.997 0.003
G24.8 Other dystonia
0.003 0.997 0.000
E70-E90 Metabolic disorders
0.000 0.997 0.003
E88.8 Other specified metabolic disorders
0.000 0.997 0.003
G24.5 Blepharospasm
0.003 0.997 0.000
R57 Shock, not elsewhere classified
0.000 0.997 0.003
S52.21 Fracture of shaft of ulna (open)
0.000 0.997 0.003
D52.9 Folate deficiency anaemia, unspecified
0.000 0.997 0.003
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.003 0.997 0.000
S52.9 Fracture of forearm, part unspecified
0.000 0.997 0.003
E05.9 Thyrotoxicosis, unspecified
0.003 0.997 0.000
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.997 0.003
L91.8 Other hypertrophic disorders of skin
0.003 0.997 0.000
S52.30 Fracture of shaft of radius (closed)
0.000 0.997 0.003
E88.9 Metabolic disorder, unspecified
0.000 0.997 0.003
H74.0 Tympanosclerosis
0.000 0.997 0.003
R57.9 Shock, unspecified
0.000 0.997 0.003
H74 Other disorders of middle ear and mastoid
0.000 0.997 0.003
S52.4 Fracture of shafts of both ulna and radius
0.000 0.997 0.003
E88.2 Lipomatosis, not elsewhere classified
0.000 0.997 0.003
O20.0 Threatened abortion
0.003 0.997 0.000
S92 Fracture of foot, except ankle
0.000 0.997 0.003
G24.4 Idiopathic orofacial dystonia
0.003 0.997 0.000
G24.2 Idiopathic nonfamilial dystonia
0.003 0.997 0.000
G24.1 Idiopathic familial dystonia
0.003 0.997 0.000
G24.0 Drug-induced dystonia
0.003 0.997 0.000
S50.9 Superficial injury of forearm, unspecified
0.000 0.997 0.003
S52.70 Multiple fractures of forearm (closed)
0.000 0.997 0.003
E79 Disorders of purine and pyrimidine metabolism
0.000 0.997 0.003
S52.31 Fracture of shaft of radius (open)
0.000 0.997 0.002
Z94.8 Other transplanted organ and tissue status
0.000 0.997 0.003
E84 Cystic fibrosis
0.000 0.997 0.002
S51 Open wound of forearm
0.000 0.997 0.003
M10.99 Gout, unspecified (Site unspecified)
0.000 0.997 0.003
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods
0.000 0.997 0.003
S51.7 Multiple open wounds of forearm
0.000 0.997 0.002
S52.1 Fracture of upper end of radius
0.000 0.997 0.002
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.997 0.002
S50-S59 Injuries to the elbow and forearm
0.000 0.997 0.003
E77 Disorders of glycoprotein metabolism
0.000 0.997 0.002
E76 Disorders of glycosaminoglycan metabolism
0.000 0.997 0.002
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.997 0.002
E70 Disorders of aromatic amino-acid metabolism
0.000 0.997 0.002
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.997 0.002
S52.71 Multiple fractures of forearm (open)
0.000 0.998 0.002
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.998 0.002
S59.9 Unspecified injury of forearm
0.000 0.998 0.002
S59 Other and unspecified injuries of forearm
0.000 0.998 0.002
R57.8 Other shock
0.000 0.998 0.002
E74 Other disorders of carbohydrate metabolism
0.000 0.998 0.002
H66.9 Otitis media, unspecified
0.000 0.998 0.002
S52.91 Fracture of forearm, part unspecified (open)
0.000 0.998 0.002
S52.90 Fracture of forearm, part unspecified (closed)
0.000 0.998 0.002
S91 Open wound of ankle and foot
0.000 0.998 0.002
S52.60 Fracture of lower end of both ulna and radius (closed)
0.000 0.998 0.002
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.000 0.998 0.002
S52.8 Fracture of other parts of forearm
0.000 0.998 0.002
S53.3 Traumatic rupture of ulnar collateral ligament
0.000 0.998 0.002
T78.4 Allergy, unspecified
0.000 0.998 0.002
E72 Other disorders of amino-acid metabolism
0.000 0.998 0.002
E80.6 Other disorders of bilirubin metabolism
0.000 0.998 0.002
S92.7 Multiple fractures of foot
0.000 0.998 0.002
E73 Lactose intolerance
0.000 0.998 0.002
S51.9 Open wound of forearm, part unspecified
0.000 0.998 0.002
Y04.8 Other specified place
0.002 0.998 0.000
M76.67 Achilles tendinitis (Ankle and foot)
0.002 0.998 0.000
S32.5 Fracture of pubis
0.000 0.998 0.002
S91.0 Open wound of ankle
0.000 0.998 0.002
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.998 0.002
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.998 0.002
H74.3 Other acquired abnormalities of ear ossicles
0.000 0.998 0.002
H74.2 Discontinuity and dislocation of ear ossicles
0.000 0.998 0.002
H74.8 Other specified disorders of middle ear and mastoid
0.000 0.998 0.002
R57.1 Hypovolaemic shock
0.000 0.998 0.002
R70.0 Elevated erythrocyte sedimentation rate
0.000 0.998 0.002
M40.24 Other and unspecified kyphosis (Thoracic region)
0.002 0.998 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.000 0.998 0.002
E84.9 Cystic fibrosis, unspecified
0.000 0.998 0.002
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess
0.000 0.998 0.002
S55 Injury of blood vessels at forearm level
0.000 0.998 0.002
H74.4 Polyp of middle ear
0.000 0.998 0.002
S52.41 Fracture of shafts of both ulna and radius (open)
0.000 0.998 0.002
D73.5 Infarction of spleen
0.000 0.998 0.002
S51.0 Open wound of elbow
0.000 0.998 0.002
S92.9 Fracture of foot, unspecified
0.000 0.998 0.002
S92.4 Fracture of great toe
0.000 0.998 0.002
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.998 0.002
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.998 0.002
E79.1 Lesch-Nyhan syndrome
0.000 0.998 0.002
S92.5 Fracture of other toe
0.000 0.998 0.002
S52.11 Fracture of upper end of radius (open)
0.000 0.998 0.002
E80.1 Porphyria cutanea tarda
0.000 0.998 0.002
H74.1 Adhesive middle ear disease
0.000 0.998 0.002
K06.2 Gingival and edentulous alveolar ridge lesions associated with trauma
0.000 0.998 0.002
T79.6 Traumatic ischaemia of muscle
0.002 0.998 0.000
S92.51 Fracture of other toe (open)
0.000 0.998 0.002
E75.5 Other lipid storage disorders
0.000 0.998 0.002
E84.8 Cystic fibrosis with other manifestations
0.000 0.998 0.002
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.998 0.002
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.998 0.002
S92.2 Fracture of other tarsal bone(s)
0.000 0.998 0.002
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)
0.000 0.998 0.002
S52.40 Fracture of shafts of both ulna and radius (closed)
0.000 0.998 0.002
E75.6 Lipid storage disorder, unspecified
0.000 0.998 0.002
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.998 0.002
E75.3 Sphingolipidosis, unspecified
0.000 0.998 0.002
E75.2 Other sphingolipidosis
0.000 0.998 0.002
E75.1 Other gangliosidosis
0.000 0.998 0.002
E75.0 GM2 gangliosidosis
0.000 0.998 0.002
G30.9 Alzheimer's disease, unspecified
0.002 0.998 0.000
S58 Traumatic amputation of forearm
0.000 0.998 0.002
S57 Crushing injury of forearm
0.000 0.998 0.002
M00.96 Pyogenic arthritis, unspecified (Lower leg)
0.000 0.998 0.002
S92.70 Multiple fractures of foot (closed)
0.000 0.998 0.002
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.998 0.002
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.998 0.002
E70.3 Albinism
0.000 0.998 0.002
E70.2 Disorders of tyrosine metabolism
0.000 0.998 0.002
E70.1 Other hyperphenylalaninaemias
0.000 0.998 0.002
E70.0 Classical phenylketonuria
0.000 0.998 0.002
E71.3 Disorders of fatty-acid metabolism
0.000 0.998 0.002
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.998 0.002
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.998 0.002
E71.0 Maple-syrup-urine disease
0.000 0.998 0.002
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.998 0.002
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.998 0.002
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.998 0.002
E76.2 Other mucopolysaccharidoses
0.000 0.998 0.002
E76.1 Mucopolysaccharidosis, type II
0.000 0.998 0.002
E76.0 Mucopolysaccharidosis, type I
0.000 0.998 0.002
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.998 0.002
E77.8 Other disorders of glycoprotein metabolism
0.000 0.998 0.002
E77.1 Defects in glycoprotein degradation
0.000 0.998 0.002
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.998 0.002
I21.2 Acute transmural myocardial infarction of other sites
0.002 0.998 0.000
S50 Superficial injury of forearm
0.000 0.998 0.002
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.998 0.002
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.998 0.002
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.998 0.002
E74.2 Disorders of galactose metabolism
0.000 0.998 0.002
E74.1 Disorders of fructose metabolism
0.000 0.998 0.002
E74.0 Glycogen storage disease
0.000 0.998 0.002
E87.0 Hyperosmolality and hypernatraemia
0.000 0.998 0.002
H52.3 Anisometropia and aniseikonia
0.000 0.998 0.002
M93.9 Osteochondropathy, unspecified
0.000 0.998 0.002
S53.4 Sprain and strain of elbow
0.000 0.998 0.002
S55.1 Injury of radial artery at forearm level
0.000 0.998 0.002
S59.8 Other specified injuries of forearm
0.000 0.998 0.002
S59.7 Multiple injuries of forearm
0.000 0.998 0.002
D69 Purpura and other haemorrhagic conditions
0.000 0.998 0.002
S91.7 Multiple open wounds of ankle and foot
0.000 0.998 0.002
K06 Other disorders of gingiva and edentulous alveolar ridge
0.000 0.998 0.002
S53.1 Dislocation of elbow, unspecified
0.000 0.998 0.002
S92.0 Fracture of calcaneus
0.000 0.998 0.002
K57 Diverticular disease of intestine
0.000 0.998 0.002
Y04 Assault by bodily force
0.002 0.998 0.000
S52.81 Fracture of other parts of forearm (open)
0.000 0.998 0.002
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.998 0.002
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.998 0.002
E72.5 Disorders of glycine metabolism
0.000 0.998 0.002
E72.4 Disorders of ornithine metabolism
0.000 0.998 0.002
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.998 0.002
E72.2 Disorders of urea cycle metabolism
0.000 0.998 0.002
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.998 0.002
S53.0 Dislocation of radial head
0.000 0.998 0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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