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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs72602052
log Bayes Factor = 12.3687
Chromosome 7   position 28,500,531  (GRCh37) Explore rs72602052 on Ensembl!
Variant rs72602052 is part of Cluster X0226

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25.8 Other forms of chronic ischaemic heart disease
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
I25.1 Atherosclerotic heart disease
0.998 0.002 0.000
E10-E14 Diabetes mellitus
0.998 0.002 0.000
Chapter I Certain infectious and parasitic diseases
0.996 0.004 0.000
E10 Insulin-dependent diabetes mellitus
0.996 0.004 0.000
Chapter VIII Diseases of the ear and mastoid process
0.995 0.005 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.984 0.016 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.981 0.019 0.000
E10.9 Without complications
0.978 0.022 0.000
H65-H75 Diseases of middle ear and mastoid
0.975 0.025 0.000
B95-B98 Bacterial, viral and other infectious agents
0.973 0.027 0.000
I20-I25 Ischaemic heart diseases
0.972 0.028 0.000
E70-E90 Metabolic disorders
0.969 0.031 0.000
E83 Disorders of mineral metabolism
0.964 0.036 0.000
I20 Angina pectoris
0.962 0.038 0.000
M80-M85 Disorders of bone density and structure
0.961 0.039 0.000
E83.1 Disorders of iron metabolism
0.960 0.040 0.000
I25.2 Old myocardial infarction
0.959 0.041 0.000
I20.9 Angina pectoris, unspecified
0.952 0.048 0.000
M84 Disorders of continuity of bone
0.946 0.054 0.000
M20-M25 Other joint disorders
0.940 0.060 0.000
H80-H83 Diseases of inner ear
0.939 0.061 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.936 0.064 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.934 0.066 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.932 0.068 0.000
M25 Other joint disorders, not elsewhere classified
0.931 0.069 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.921 0.079 0.000
S80-S89 Injuries to the knee and lower leg
0.919 0.081 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.917 0.083 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.913 0.087 0.000
H66 Suppurative and unspecified otitis media
0.913 0.087 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.906 0.094 0.000
Chapter IX Diseases of the circulatory system
0.904 0.096 0.000
T92 Sequelae of injuries of upper limb
0.903 0.097 0.000
I20.0 Unstable angina
0.902 0.098 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.902 0.098 0.000
Chapter VII Diseases of the eye and adnexa
0.901 0.099 0.000
E10.3 With ophthalmic complications
0.900 0.100 0.000
S50-S59 Injuries to the elbow and forearm
0.897 0.103 0.000
M25.8 Other specified joint disorders
0.893 0.107 0.000
H83 Other diseases of inner ear
0.886 0.114 0.000
S20-S29 Injuries to the thorax
0.884 0.116 0.000
M86-M90 Other osteopathies
0.876 0.124 0.000
Chapter X Diseases of the respiratory system
0.872 0.128 0.000
M70-M79 Other soft tissue disorders
0.871 0.129 0.000
H66.3 Other chronic suppurative otitis media
0.869 0.131 0.000
B65-B83 Helminthiases
0.865 0.135 0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)
0.862 0.138 0.000
E83.4 Disorders of magnesium metabolism
0.861 0.139 0.000
B07 Viral warts
0.860 0.140 0.000
E14 Unspecified diabetes mellitus
0.857 0.143 0.000
Chapter XXII Codes for special purposes
0.857 0.143 0.000
T79-T79 Certain early complications of trauma
0.855 0.145 0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)
0.853 0.147 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.851 0.149 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.851 0.149 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.850 0.150 0.000
H74 Other disorders of middle ear and mastoid
0.849 0.151 0.000
H83.0 Labyrinthitis
0.848 0.152 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.847 0.153 0.000
B15-B19 Viral hepatitis
0.843 0.157 0.000
J00-J06 Acute upper respiratory infections
0.843 0.157 0.000
E10.5 With peripheral circulatory complications
0.842 0.158 0.000
E10.2 With renal complications
0.841 0.159 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.836 0.164 0.000
M21 Other acquired deformities of limbs
0.835 0.165 0.000
H25-H28 Disorders of lens
0.832 0.168 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.831 0.169 0.000
E65-E68 Obesity and other hyperalimentation
0.831 0.169 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.827 0.173 0.000
S90-S99 Injuries to the ankle and foot
0.826 0.174 0.000
S10-S19 Injuries to the neck
0.826 0.174 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.826 0.174 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.825 0.175 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.823 0.177 0.000
S32 Fracture of lumbar spine and pelvis
0.821 0.179 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.820 0.180 0.000
I25.3 Aneurysm of heart
0.820 0.180 0.000
M25.5 Pain in joint
0.813 0.187 0.000
N85.2 Hypertrophy of uterus
0.812 0.188 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.811 0.189 0.000
Chapter XIV Diseases of the genitourinary system
0.810 0.190 0.000
H21 Other disorders of iris and ciliary body
0.809 0.191 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.809 0.191 0.000
M25.57 Pain in joint (Ankle and foot)
0.808 0.192 0.000
M05-M14 Inflammatory polyarthropathies
0.807 0.193 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.806 0.194 0.000
H60-H62 Diseases of external ear
0.802 0.198 0.000
J20-J22 Other acute lower respiratory infections
0.800 0.200 0.000
E10.4 With neurological complications
0.794 0.206 0.000
J00 Acute nasopharyngitis [common cold]
0.794 0.206 0.000
H81 Disorders of vestibular function
0.791 0.209 0.000
S31 Open wound of abdomen, lower back and pelvis
0.789 0.211 0.000
H30-H36 Disorders of choroid and retina
0.785 0.215 0.000
M87 Osteonecrosis
0.783 0.217 0.000
S22.0 Fracture of thoracic vertebra
0.781 0.219 0.000
M25.3 Other instability of joint
0.781 0.219 0.000
M79.6 Pain in limb
0.781 0.219 0.000
E11 Non-insulin-dependent diabetes mellitus
0.780 0.220 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.777 0.223 0.000
M25.87 Other specified joint disorders (Ankle and foot)
0.776 0.224 0.000
N92 Excessive, frequent and irregular menstruation
0.774 0.226 0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)
0.773 0.227 0.000
H65 Nonsuppurative otitis media
0.773 0.227 0.000
B25-B34 Other viral diseases
0.772 0.228 0.000
B80 Enterobiasis
0.771 0.229 0.000
Q50-Q56 Congenital malformations of genital organs
0.771 0.229 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.771 0.229 0.000
M25.86 Other specified joint disorders (Lower leg)
0.771 0.229 0.000
M60-M63 Disorders of muscles
0.769 0.230 0.000
S70-S79 Injuries to the hip and thigh
0.768 0.232 0.000
S40-S49 Injuries to the shoulder and upper arm
0.767 0.233 0.000
S86 Injury of muscle and tendon at lower leg level
0.767 0.233 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.766 0.234 0.000
M80 Osteoporosis with pathological fracture
0.764 0.236 0.000
T90 Sequelae of injuries of head
0.764 0.236 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.762 0.238 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.759 0.241 0.000
H66.2 Chronic atticoantral suppurative otitis media
0.759 0.241 0.000
M79.8 Other specified soft tissue disorders
0.758 0.242 0.000
B02 Zoster [herpes zoster]
0.756 0.244 0.000
N85.0 Endometrial glandular hyperplasia
0.756 0.244 0.000
H71 Cholesteatoma of middle ear
0.756 0.244 0.000
M79.66 Pain in limb (Lower leg)
0.756 0.244 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.755 0.245 0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb
0.753 0.247 0.000
S50 Superficial injury of forearm
0.753 0.247 0.000
M32 Systemic lupus erythematosus
0.752 0.247 0.000
M35 Other systemic involvement of connective tissue
0.752 0.248 0.000
E88 Other metabolic disorders
0.752 0.248 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.751 0.249 0.000
A00-A09 Intestinal infectious diseases
0.750 0.250 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.750 0.250 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.749 0.251 0.000
S22.00 Fracture of thoracic vertebra (closed)
0.748 0.252 0.000
B50-B64 Protozoal diseases
0.748 0.252 0.000
E10.8 With unspecified complications
0.748 0.252 0.000
M82 Osteoporosis in diseases classified elsewhere
0.748 0.252 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.747 0.253 0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters
0.747 0.253 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.747 0.253 0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)
0.745 0.255 0.000
A80-A89 Viral infections of the central nervous system
0.745 0.255 0.000
N92.1 Excessive and frequent menstruation with irregular cycle
0.745 0.255 0.000
I25.4 Coronary artery aneurysm
0.744 0.256 0.000
H70 Mastoiditis and related conditions
0.744 0.256 0.000
T20 Burn and corrosion of head and neck
0.744 0.256 0.000
S51 Open wound of forearm
0.741 0.259 0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)
0.740 0.260 0.000
T91 Sequelae of injuries of neck and trunk
0.738 0.262 0.000
A65-A69 Other spirochaetal diseases
0.738 0.262 0.000
M24 Other specific joint derangements
0.737 0.263 0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb
0.737 0.263 0.000
T23 Burn and corrosion of wrist and hand
0.736 0.264 0.000
M21.0 Valgus deformity, not elsewhere classified
0.735 0.265 0.000
H27 Other disorders of lens
0.734 0.266 0.000
M84.0 Malunion of fracture
0.733 0.267 0.000
Q00-Q07 Congenital malformations of the nervous system
0.733 0.267 0.000
M00-M03 Infectious arthropathies
0.731 0.268 0.000
J95-J99 Other diseases of the respiratory system
0.726 0.274 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.725 0.275 0.000
H17 Corneal scars and opacities
0.725 0.275 0.000
S83.6 Sprain and strain of other and unspecified parts of knee
0.723 0.276 0.000
M25.4 Effusion of joint
0.719 0.281 0.000
S21 Open wound of thorax
0.719 0.281 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.719 0.281 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.718 0.282 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.716 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.715 0.285 0.000
H72 Perforation of tympanic membrane
0.715 0.285 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.715 0.285 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.714 0.286 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.714 0.286 0.000
A75-A79 Rickettsioses
0.714 0.286 0.000
A70-A74 Other diseases caused by chlamydiae
0.714 0.286 0.000
A20-A28 Certain zoonotic bacterial diseases
0.714 0.286 0.000
A15-A19 Tuberculosis
0.714 0.286 0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)
0.714 0.286 0.000
E10.7 With multiple complications
0.714 0.286 0.000
E10.6 With other specified complications
0.714 0.286 0.000
E10.0 With coma
0.714 0.286 0.000
H36 Retinal disorders in diseases classified elsewhere
0.713 0.287 0.000
B18 Chronic viral hepatitis
0.712 0.288 0.000
E14.3 With ophthalmic complications
0.711 0.289 0.000
M11 Other crystal arthropathies
0.711 0.289 0.000
S99 Other and unspecified injuries of ankle and foot
0.710 0.290 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.710 0.290 0.000
S83.2 Tear of meniscus, current
0.709 0.291 0.000
H73 Other disorders of tympanic membrane
0.709 0.291 0.000
M25.81 Other specified joint disorders (Shoulder region)
0.708 0.292 0.000
H74.8 Other specified disorders of middle ear and mastoid
0.708 0.292 0.000
J22 Unspecified acute lower respiratory infection
0.708 0.292 0.000
I23 Certain current complications following acute myocardial infarction
0.706 0.293 0.000
S32.0 Fracture of lumbar vertebra
0.706 0.294 0.000
N00-N08 Glomerular diseases
0.705 0.295 0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.704 0.296 0.000
I25.5 Ischaemic cardiomyopathy
0.704 0.296 0.000
J01 Acute sinusitis
0.704 0.296 0.000
T92.0 Sequelae of open wound of upper limb
0.703 0.297 0.000
J03 Acute tonsillitis
0.701 0.299 0.000
T31 Burns classified according to extent of body surface involved
0.700 0.299 0.000
E66 Obesity
0.700 0.300 0.000
Chapter VI Diseases of the nervous system
0.700 0.300 0.000
M40-M43 Deforming dorsopathies
0.699 0.301 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.699 0.301 0.000
H68 Eustachian salpingitis and obstruction
0.699 0.301 0.000
H67 Otitis media in diseases classified elsewhere
0.699 0.301 0.000
M21.1 Varus deformity, not elsewhere classified
0.698 0.302 0.000
E50-E64 Other nutritional deficiencies
0.698 0.302 0.000
E74 Other disorders of carbohydrate metabolism
0.698 0.302 0.000
N85.8 Other specified noninflammatory disorders of uterus
0.697 0.303 0.000
S31.1 Open wound of abdominal wall
0.696 0.304 0.000
H21.1 Other vascular disorders of iris and ciliary body
0.696 0.304 0.000
M25.9 Joint disorder, unspecified
0.696 0.304 0.000
M84.4 Pathological fracture, not elsewhere classified
0.695 0.305 0.000
H20 Iridocyclitis
0.695 0.305 0.000
H21.5 Other adhesions and disruptions of iris and ciliary body
0.695 0.305 0.000
E84 Cystic fibrosis
0.694 0.305 0.000
E79 Disorders of purine and pyrimidine metabolism
0.694 0.305 0.000
E77 Disorders of glycoprotein metabolism
0.694 0.305 0.000
E76 Disorders of glycosaminoglycan metabolism
0.694 0.305 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.694 0.305 0.000
E72 Other disorders of amino-acid metabolism
0.694 0.305 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.694 0.305 0.000
E70 Disorders of aromatic amino-acid metabolism
0.694 0.305 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.694 0.305 0.000
N94.8 Other specified conditions associated with female genital organs and menstrual cycle
0.693 0.307 0.000
M33 Dermatopolymyositis
0.693 0.307 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.691 0.309 0.000
E83.8 Other disorders of mineral metabolism
0.691 0.309 0.000
E83.2 Disorders of zinc metabolism
0.691 0.309 0.000
E83.0 Disorders of copper metabolism
0.691 0.309 0.000
E14.9 Without complications
0.690 0.310 0.000
S89 Other and unspecified injuries of lower leg
0.690 0.310 0.000
M83 Adult osteomalacia
0.689 0.311 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.689 0.311 0.000
N92.0 Excessive and frequent menstruation with regular cycle
0.688 0.312 0.000
M86 Osteomyelitis
0.688 0.312 0.000
S80 Superficial injury of lower leg
0.688 0.312 0.000
T66-T78 Other and unspecified effects of external causes
0.686 0.313 0.000
S83.3 Tear of articular cartilage of knee, current
0.686 0.314 0.000
M77 Other enthesopathies
0.686 0.314 0.000
H21.8 Other specified disorders of iris and ciliary body
0.686 0.314 0.000
S54 Injury of nerves at forearm level
0.686 0.314 0.000
H26 Other cataract
0.686 0.314 0.000
J04 Acute laryngitis and tracheitis
0.684 0.316 0.000
T79.6 Traumatic ischaemia of muscle
0.683 0.317 0.000
B02.3 Zoster ocular disease
0.682 0.318 0.000
N80 Endometriosis
0.682 0.318 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.681 0.319 0.000
E11.3 With ophthalmic complications
0.680 0.320 0.000
E11.1 With ketoacidosis
0.680 0.320 0.000
M84.9 Disorder of continuity of bone, unspecified
0.678 0.321 0.000
M84.8 Other disorders of continuity of bone
0.678 0.321 0.000
M84.3 Stress fracture, not elsewhere classified
0.678 0.321 0.000
M84.2 Delayed union of fracture
0.678 0.321 0.000
M87.9 Osteonecrosis, unspecified
0.678 0.322 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.678 0.322 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.677 0.323 0.000
B01 Varicella [chickenpox]
0.675 0.325 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.674 0.326 0.000
M30 Polyarteritis nodosa and related conditions
0.674 0.326 0.000
N80.0 Endometriosis of uterus
0.674 0.326 0.000
H82 Vertiginous syndromes in diseases classified elsewhere
0.673 0.327 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.672 0.328 0.000
N81 Female genital prolapse
0.672 0.328 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.671 0.328 0.000
S32.7 Multiple fractures of lumbar spine and pelvis
0.671 0.329 0.000
T95 Sequelae of burns, corrosions and frostbite
0.671 0.329 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.671 0.329 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.671 0.329 0.000
T92.1 Sequelae of fracture of arm
0.671 0.329 0.000
Q80-Q89 Other congenital malformations
0.671 0.329 0.000
H81.2 Vestibular neuronitis
0.670 0.330 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.670 0.330 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.670 0.330 0.000
T92.9 Sequelae of unspecified injury of upper limb
0.669 0.331 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.669 0.331 0.000
S22.1 Multiple fractures of thoracic spine
0.668 0.331 0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)
0.668 0.332 0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)
0.668 0.332 0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)
0.668 0.332 0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)
0.668 0.332 0.000
M25.2 Flail joint
0.667 0.333 0.000
M25.1 Fistula of joint
0.667 0.333 0.000
S14 Injury of nerves and spinal cord at neck level
0.667 0.333 0.000
N81.6 Rectocele
0.667 0.333 0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)
0.666 0.334 0.000
M89 Other disorders of bone
0.665 0.335 0.000
H53-H54 Visual disturbances and blindness
0.665 0.335 0.000
Q60-Q64 Congenital malformations of the urinary system
0.664 0.336 0.000
N85.4 Malposition of uterus
0.664 0.336 0.000
S71 Open wound of hip and thigh
0.662 0.338 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.661 0.338 0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)
0.661 0.339 0.000
H65.4 Other chronic nonsuppurative otitis media
0.661 0.339 0.000
B06 Rubella [German measles]
0.660 0.339 0.000
B05 Measles
0.660 0.339 0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions
0.660 0.339 0.000
B04 Monkeypox
0.660 0.339 0.000
B03 Smallpox
0.660 0.339 0.000
H36.0 Diabetic retinopathy
0.661 0.339 0.000
M87.8 Other osteonecrosis
0.660 0.340 0.000
S88 Traumatic amputation of lower leg
0.659 0.341 0.000
S87 Crushing injury of lower leg
0.659 0.341 0.000
S85 Injury of blood vessels at lower leg level
0.659 0.341 0.000
S84 Injury of nerves at lower leg level
0.659 0.341 0.000
T14 Injury of unspecified body region
0.659 0.341 0.000
S86.8 Injury of other muscles and tendons at lower leg level
0.658 0.342 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.658 0.342 0.000
S37 Injury of urinary and pelvic organs
0.658 0.342 0.000
S36 Injury of intra-abdominal organs
0.658 0.342 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.658 0.342 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.658 0.342 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.658 0.342 0.000
J21 Acute bronchiolitis
0.657 0.342 0.000
H33 Retinal detachments and breaks
0.657 0.343 0.000
B15 Acute hepatitis A
0.657 0.343 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.657 0.343 0.000
E40-E46 Malnutrition
0.656 0.344 0.000
T25 Burn and corrosion of ankle and foot
0.655 0.345 0.000
T21 Burn and corrosion of trunk
0.655 0.345 0.000
E85 Amyloidosis
0.654 0.345 0.000
H66.4 Suppurative otitis media, unspecified
0.654 0.346 0.000
H66.1 Chronic tubotympanic suppurative otitis media
0.654 0.346 0.000
H66.0 Acute suppurative otitis media
0.654 0.346 0.000
E11.2 With renal complications
0.654 0.346 0.000
B25 Cytomegaloviral disease
0.654 0.346 0.000
H69 Other disorders of Eustachian tube
0.653 0.347 0.000
H61 Other disorders of external ear
0.652 0.348 0.000
H74.0 Tympanosclerosis
0.652 0.348 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.650 0.350 0.000
H74.4 Polyp of middle ear
0.650 0.350 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.649 0.350 0.000
Q35-Q37 Cleft lip and cleft palate
0.649 0.350 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.649 0.350 0.000
E78.0 Pure hypercholesterolaemia
0.649 0.351 0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)
0.649 0.351 0.000
S51.7 Multiple open wounds of forearm
0.648 0.352 0.000
I00-I02 Acute rheumatic fever
0.648 0.352 0.000
S27 Injury of other and unspecified intrathoracic organs
0.648 0.352 0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb
0.647 0.352 0.000
T92.4 Sequelae of injury of nerve of upper limb
0.647 0.352 0.000
N85.9 Noninflammatory disorder of uterus, unspecified
0.646 0.354 0.000
E73 Lactose intolerance
0.645 0.355 0.000
M35.3 Polymyalgia rheumatica
0.645 0.355 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.645 0.355 0.000
H74.9 Disorder of middle ear and mastoid, unspecified
0.645 0.355 0.000
T90.4 Sequelae of injury of eye and orbit
0.644 0.356 0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters
0.644 0.356 0.000
N85.1 Endometrial adenomatous hyperplasia
0.644 0.356 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.644 0.356 0.000
T91.3 Sequelae of injury of spinal cord
0.644 0.356 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.644 0.356 0.000
S59 Other and unspecified injuries of forearm
0.643 0.357 0.000
S58 Traumatic amputation of forearm
0.643 0.357 0.000
S57 Crushing injury of forearm
0.643 0.357 0.000
S55 Injury of blood vessels at forearm level
0.643 0.357 0.000
M65-M68 Disorders of synovium and tendon
0.643 0.357 0.000
H25 Senile cataract
0.642 0.358 0.000
J40-J47 Chronic lower respiratory diseases
0.642 0.358 0.000
M25.33 Other instability of joint (Forearm)
0.642 0.358 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.642 0.358 0.000
B18.2 Chronic viral hepatitis C
0.641 0.359 0.000
M25.89 Other specified joint disorders (Site unspecified)
0.640 0.360 0.000
M25.88 Other specified joint disorders (Other)
0.640 0.360 0.000
M25.83 Other specified joint disorders (Forearm)
0.640 0.360 0.000
M25.82 Other specified joint disorders (Upper arm)
0.640 0.360 0.000
M25.80 Other specified joint disorders (Multiple sites)
0.640 0.360 0.000
J47 Bronchiectasis
0.639 0.361 0.000
S82 Fracture of lower leg, including ankle
0.637 0.363 0.000
E13 Other specified diabetes mellitus
0.636 0.363 0.000
Q51 Congenital malformations of uterus and cervix
0.636 0.364 0.000
H90-H95 Other disorders of ear
0.636 0.364 0.000
N92.4 Excessive bleeding in the premenopausal period
0.636 0.364 0.000
S56 Injury of muscle and tendon at forearm level
0.636 0.364 0.000
H83.9 Disease of inner ear, unspecified
0.635 0.365 0.000
H83.8 Other specified diseases of inner ear
0.635 0.365 0.000
H83.3 Noise effects on inner ear
0.635 0.365 0.000
H83.2 Labyrinthine dysfunction
0.635 0.365 0.000
H83.1 Labyrinthine fistula
0.635 0.365 0.000
E86 Volume depletion
0.634 0.366 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.634 0.366 0.000
S26 Injury of heart
0.634 0.366 0.000
S25 Injury of blood vessels of thorax
0.634 0.366 0.000
S24 Injury of nerves and spinal cord at thorax level
0.634 0.366 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.634 0.366 0.000
S42 Fracture of shoulder and upper arm
0.633 0.367 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.633 0.367 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.632 0.368 0.000
M79.82 Other specified soft tissue disorders (Upper arm)
0.632 0.368 0.000
S12 Fracture of neck
0.631 0.369 0.000
M06 Other rheumatoid arthritis
0.631 0.369 0.000
E83.5 Disorders of calcium metabolism
0.630 0.370 0.000
B17 Other acute viral hepatitis
0.629 0.371 0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)
0.629 0.371 0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis
0.628 0.372 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.627 0.372 0.000
S99.9 Unspecified injury of ankle and foot
0.627 0.372 0.000
M22 Disorders of patella
0.627 0.373 0.000
M10 Gout
0.627 0.373 0.000
S92 Fracture of foot, except ankle
0.627 0.373 0.000
S52 Fracture of forearm
0.626 0.374 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.626 0.374 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.624 0.375 0.000
T23.2 Burn of second degree of wrist and hand
0.624 0.376 0.000
S32.00 Fracture of lumbar vertebra (closed)
0.623 0.376 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.623 0.377 0.000
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand
0.623 0.377 0.000
M21.6 Other acquired deformities of ankle and foot
0.623 0.377 0.000
M79.2 Neuralgia and neuritis, unspecified
0.623 0.377 0.000
S22.4 Multiple fractures of ribs
0.623 0.377 0.000
H26.2 Complicated cataract
0.623 0.377 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.622 0.378 0.000
M88 Paget's disease of bone [osteitis deformans]
0.621 0.379 0.000
T98 Sequelae of other and unspecified effects of external causes
0.621 0.379 0.000
B83 Other helminthiases
0.620 0.380 0.000
B82 Unspecified intestinal parasitism
0.620 0.380 0.000
B81 Other intestinal helminthiases, not elsewhere classified
0.620 0.380 0.000
B78 Strongyloidiasis
0.620 0.380 0.000
B77 Ascariasis
0.620 0.380 0.000
B76 Hookworm diseases
0.620 0.380 0.000
B74 Filariasis
0.620 0.380 0.000
B71 Other cestode infections
0.620 0.380 0.000
B70 Diphyllobothriasis and sparganosis
0.620 0.380 0.000
B69 Cysticercosis
0.620 0.380 0.000
B68 Taeniasis
0.620 0.380 0.000
B67 Echinococcosis
0.620 0.380 0.000
B66 Other fluke infections
0.620 0.380 0.000
B65 Schistosomiasis [bilharziasis]
0.620 0.380 0.000
B79 Trichuriasis
0.620 0.380 0.000
B75 Trichinellosis
0.620 0.380 0.000
B73 Onchocerciasis
0.620 0.380 0.000
B72 Dracunculiasis
0.620 0.380 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.620 0.380 0.000
M70.2 Olecranon bursitis
0.619 0.381 0.000
T90.9 Sequelae of unspecified injury of head
0.619 0.381 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.619 0.381 0.000
S32.4 Fracture of acetabulum
0.619 0.381 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.618 0.382 0.000
H72.0 Central perforation of tympanic membrane
0.617 0.383 0.000
A63.0 Anogenital (venereal) warts
0.617 0.383 0.000
B99-B99 Other infectious diseases
0.616 0.384 0.000
N94.5 Secondary dysmenorrhoea
0.615 0.385 0.000
N25-N29 Other disorders of kidney and ureter
0.615 0.385 0.000
E14.8 With unspecified complications
0.615 0.385 0.000
E14.7 With multiple complications
0.615 0.385 0.000
E14.6 With other specified complications
0.615 0.385 0.000
E14.5 With peripheral circulatory complications
0.615 0.385 0.000
E14.4 With neurological complications
0.615 0.385 0.000
E14.2 Withrenal complications
0.615 0.385 0.000
E14.1 With ketoacidosis
0.615 0.385 0.000
E14.0 With coma
0.615 0.385 0.000
E65 Localised adiposity
0.615 0.385 0.000
E10.1 With ketoacidosis
0.614 0.386 0.000
H27.8 Other specified disorders of lens
0.614 0.386 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.614 0.386 0.000
J98 Other respiratory disorders
0.614 0.386 0.000
M11.2 Other chondrocalcinosis
0.613 0.386 0.000
M21.4 Flat foot [pes planus] (acquired)
0.613 0.387 0.000
U88 Agent resistant to multiple antibiotics
0.613 0.387 0.000
H20.9 Iridocyclitis, unspecified
0.612 0.388 0.000
H25.8 Other senile cataract
0.612 0.388 0.000
N94.9 Unspecified condition associated with female genital organs and menstrual cycle
0.611 0.389 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.610 0.389 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.610 0.389 0.000
H15 Disorders of sclera
0.610 0.389 0.000
B97.6 Parvovirus as the cause of diseases classified to other chapters
0.609 0.391 0.000
B97.5 Reovirus as the cause of diseases classified to other chapters
0.609 0.391 0.000
B97.4 Respiratory synctial virus as the cause of diseases classified to other chapters
0.609 0.391 0.000
B97.3 Retrovirus as the cause of diseases classified to other chapters
0.609 0.391 0.000
B97.2 Coronavirus as the cause of diseases classified to other chapters
0.609 0.391 0.000
B97.1 Enterovirus as the cause of diseases classified to other chapters
0.609 0.391 0.000
B97.0 Adenovirus as the cause of diseases classified to other chapters
0.609 0.391 0.000
M25.84 Other specified joint disorders (Hand)
0.609 0.391 0.000
E80.4 Gilbert's syndrome
0.609 0.391 0.000
H74.2 Discontinuity and dislocation of ear ossicles
0.608 0.391 0.000
H74.1 Adhesive middle ear disease
0.608 0.391 0.000
A30-A49 Other bacterial diseases
0.609 0.391 0.000
M76 Enthesopathies of lower limb, excluding foot
0.608 0.392 0.000
N93 Other abnormal uterine and vaginal bleeding
0.608 0.392 0.000
S83.7 Injury to multiple structures of knee
0.607 0.392 0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee
0.607 0.392 0.000
S83.1 Dislocation of knee
0.607 0.392 0.000
S83.0 Dislocation of patella
0.607 0.392 0.000
M81 Osteoporosis without pathological fracture
0.606 0.394 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.606 0.394 0.000
M60 Myositis
0.606 0.394 0.000
M25.53 Pain in joint (Forearm)
0.606 0.394 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.606 0.394 0.000
N05 Unspecified nephritic syndrome
0.605 0.395 0.000
M25.36 Other instability of joint (Lower leg)
0.605 0.395 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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