TreeWAS – Variant ID: rs72681282

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XV Pregnancy, childbirth and the puerperium	1.000	0.000
Chapter XI Diseases of the digestive system	0.999	0.001
K70-K77 Diseases of liver	0.998	0.002
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.996	0.004
Chapter VI Diseases of the nervous system	0.995	0.005
Chapter XII Diseases of the skin and subcutaneous tissue	0.994	0.006
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.994	0.006
O60-O75 Complications of labour and delivery	0.991	0.009
Chapter IX Diseases of the circulatory system	0.991	0.009
Chapter XX External causes of morbidity and mortality	0.990	0.010
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.985	0.015
K76 Other diseases of liver	0.980	0.020
I70-I79 Diseases of arteries, arterioles and capillaries	0.974	0.026
Chapter II Neoplasms	0.970	0.030
G40-G47 Episodic and paroxysmal disorders	0.967	0.033
Chapter IV Endocrine, nutritional and metabolic diseases	0.967	0.033
O20-O29 Other maternal disorders predominantly related to pregnancy	0.959	0.041
E70-E90 Metabolic disorders	0.959	0.041
Chapter X Diseases of the respiratory system	0.957	0.043
Chapter VIII Diseases of the ear and mastoid process	0.956	0.044
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.956	0.044
E87 Other disorders of fluid, electrolyte and acid-base balance	0.955	0.045
K70 Alcoholic liver disease	0.954	0.046
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.953	0.047
I60-I69 Cerebrovascular diseases	0.952	0.048
G40 Epilepsy	0.952	0.048
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.951	0.049
O94-O99 Other obstetric conditions, not elsewhere classified	0.946	0.054
Chapter I Certain infectious and parasitic diseases	0.946	0.054
M15-M19 Arthrosis	0.943	0.057
L60-L75 Disorders of skin appendages	0.935	0.065
L20-L30 Dermatitis and eczema	0.933	0.067
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.933	0.067
M70-M79 Other soft tissue disorders	0.931	0.069
K76.9 Liver disease, unspecified	0.931	0.069
C15-C26 Malignant neoplasms of digestive organs	0.930	0.070
O63 Long labour	0.929	0.071
L00-L08 Infections of the skin and subcutaneous tissue	0.926	0.074
I69 Sequelae of cerebrovascular disease	0.925	0.075
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.922	0.078
I30-I52 Other forms of heart disease	0.918	0.082
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.910	0.090
M20-M25 Other joint disorders	0.909	0.091
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.907	0.093
H60-H62 Diseases of external ear	0.904	0.096
E87.6 Hypokalaemia	0.904	0.096
I73 Other peripheral vascular diseases	0.903	0.097
O34 Maternal care for known or suspected abnormality of pelvic organs	0.902	0.098
M19 Other arthrosis	0.902	0.098
E87.2 Acidosis	0.896	0.104
J20-J22 Other acute lower respiratory infections	0.893	0.107
K83 Other diseases of biliary tract	0.889	0.111
K74 Fibrosis and cirrhosis of liver	0.888	0.112
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.885	0.115
L72 Follicular cysts of skin and subcutaneous tissue	0.883	0.117
G20-G26 Extrapyramidal and movement disorders	0.880	0.120
O36 Maternal care for other known or suspected foetal problems	0.880	0.120
M50-M54 Other dorsopathies	0.879	0.121
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.878	0.122
I73.9 Peripheral vascular disease, unspecified	0.875	0.125
T66-T78 Other and unspecified effects of external causes	0.873	0.127
G40.9 Epilepsy, unspecified	0.869	0.131
L29 Pruritus	0.869	0.131
J09-J18 Influenza and pneumonia	0.867	0.133
L72.0 Epidermal cyst	0.866	0.134
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.866	0.134
O63.1 Prolonged second stage (of labour)	0.865	0.135
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.864	0.136
T92 Sequelae of injuries of upper limb	0.864	0.136
O26 Maternal care for other conditions predominantly related to pregnancy	0.864	0.136
D60-D64 Aplastic and other anaemias	0.863	0.137
G80-G83 Cerebral palsy and other paralytic syndromes	0.862	0.138
K70.3 Alcoholic cirrhosis of liver	0.862	0.138
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.862	0.138
M19.9 Arthrosis, unspecified	0.861	0.139
B95-B98 Bacterial, viral and other infectious agents	0.856	0.144
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.854	0.146
M18 Arthrosis of first carpometacarpal joint	0.853	0.147
C78.7 Secondary malignant neoplasm of liver	0.853	0.147
G90-G99 Other disorders of the nervous system	0.850	0.150
K80 Cholelithiasis	0.849	0.151
G30-G32 Other degenerative diseases of the nervous system	0.848	0.152
O75 Other complications of labour and delivery, not elsewhere classified	0.847	0.153
L08 Other local infections of skin and subcutaneous tissue	0.847	0.153
T93 Sequelae of injuries of lower limb	0.846	0.154
O20 Haemorrhage in early pregnancy	0.846	0.154
O34.2 Maternal care due to uterine scar from previous surgery	0.842	0.158
I74 Arterial embolism and thrombosis	0.842	0.158
O47 False labour	0.839	0.161
O68 Labour and delivery complicated by foetal stress [distress]	0.838	0.162
J22 Unspecified acute lower respiratory infection	0.834	0.166
M79 Other soft tissue disorders, not elsewhere classified	0.832	0.168
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.832	0.168
M75 Shoulder lesions	0.831	0.169
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.830	0.170
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.830	0.170
M80-M85 Disorders of bone density and structure	0.829	0.171
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.828	0.172
K11 Diseases of salivary glands	0.828	0.172
L29.0 Pruritus ani	0.828	0.172
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.827	0.173
E87.5 Hyperkalaemia	0.827	0.173
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.824	0.176
C15 Malignant neoplasm of oesophagus	0.824	0.176
H61 Other disorders of external ear	0.821	0.179
I77 Other disorders of arteries and arterioles	0.821	0.179
E20-E35 Disorders of other endocrine glands	0.821	0.179
S20-S29 Injuries to the thorax	0.820	0.180
K83.1 Obstruction of bile duct	0.820	0.180
M54 Dorsalgia	0.820	0.180
K76.8 Other specified diseases of liver	0.818	0.182
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.818	0.182
M19.99 Arthrosis, unspecified (Site unspecified)	0.818	0.182
C79 Secondary malignant neoplasm of other sites	0.817	0.183
S50-S59 Injuries to the elbow and forearm	0.813	0.187
K86 Other diseases of pancreas	0.812	0.187
O26.8 Other specified pregnancy-related conditions	0.811	0.189
K70.4 Alcoholic hepatic failure	0.808	0.192
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.805	0.195
K76.0 Fatty (change of) liver, not elsewhere classified	0.805	0.195
D37-D48 Neoplasms of uncertain or unknown behaviour	0.804	0.196
I51 Complications and ill-defined descriptions of heart disease	0.802	0.198
J18 Pneumonia, organism unspecified	0.802	0.198
T92.1 Sequelae of fracture of arm	0.802	0.198
M25 Other joint disorders, not elsewhere classified	0.801	0.199
I49 Other cardiac arrhythmias	0.800	0.200
V40-V49 Car occupant injured in transport accident	0.799	0.201
I67 Other cerebrovascular diseases	0.799	0.201
K74.6 Other and unspecified cirrhosis of liver	0.798	0.202
L03 Cellulitis	0.798	0.202
O72 Postpartum haemorrhage	0.796	0.203
K76.6 Portal hypertension	0.796	0.204
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.796	0.204
V10-V19 Pedal cyclist injured in transport accident	0.796	0.204
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.795	0.205
D70-D77 Other diseases of blood and blood-forming organs	0.795	0.205
I69.3 Sequelae of cerebral infarction	0.794	0.205
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.792	0.208
M79.6 Pain in limb	0.789	0.211
J40-J47 Chronic lower respiratory diseases	0.788	0.212
I50 Heart failure	0.788	0.212
L50-L54 Urticaria and erythema	0.787	0.213
H60 Otitis externa	0.786	0.214
K70.9 Alcoholic liver disease, unspecified	0.786	0.214
V80-V89 Other land transport accidents	0.784	0.216
I35 Nonrheumatic aortic valve disorders	0.784	0.216
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.784	0.216
O62 Abnormalities of forces of labour	0.784	0.216
I70 Atherosclerosis	0.782	0.218
T79-T79 Certain early complications of trauma	0.782	0.218
M22 Disorders of patella	0.779	0.221
S70-S79 Injuries to the hip and thigh	0.779	0.221
E87.3 Alkalosis	0.779	0.221
G93 Other disorders of brain	0.778	0.222
M75.4 Impingement syndrome of shoulder	0.778	0.222
H65-H75 Diseases of middle ear and mastoid	0.778	0.222
K08 Other disorders of teeth and supporting structures	0.774	0.226
K80.4 Calculus of bile duct with cholecystitis	0.774	0.226
D00-D09 In situ neoplasms	0.773	0.227
K65-K67 Diseases of peritoneum	0.772	0.228
G81 Hemiplegia	0.770	0.230
K75 Other inflammatory liver diseases	0.769	0.231
G40.8 Other epilepsy	0.769	0.231
A30-A49 Other bacterial diseases	0.767	0.233
O32 Maternal care for known or suspected malpresentation of foetus	0.767	0.233
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.766	0.234
E83 Disorders of mineral metabolism	0.766	0.234
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.766	0.234
D62 Acute posthaemorrhagic anaemia	0.765	0.235
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.764	0.236
M18.1 Other primary arthrosis of first carpometacarpal joint	0.762	0.238
S40-S49 Injuries to the shoulder and upper arm	0.762	0.238
O64 Obstructed labour due to malposition and malpresentation of foetus	0.761	0.239
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.761	0.239
I51.8 Other ill-defined heart diseases	0.761	0.239
G20 Parkinson's disease	0.760	0.240
L27 Dermatitis due to substances taken internally	0.759	0.241
J80-J84 Other respiratory diseases principally affecting the interstitium	0.758	0.242
M19.91 Arthrosis, unspecified (Shoulder region)	0.757	0.243
I71 Aortic aneurysm and dissection	0.757	0.243
J43 Emphysema	0.756	0.244
I63 Cerebral infarction	0.755	0.245
M86-M90 Other osteopathies	0.755	0.245
O42 Premature rupture of membranes	0.754	0.246
I05-I09 Chronic rheumatic heart diseases	0.753	0.247
C25 Malignant neoplasm of pancreas	0.752	0.248
K09 Cysts of oral region, not elsewhere classified	0.751	0.249
Q60-Q64 Congenital malformations of the urinary system	0.751	0.249
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.749	0.251
L05 Pilonidal cyst	0.748	0.252
T68 Hypothermia	0.747	0.253
K04 Diseases of pulp and periapical tissues	0.746	0.254
K12 Stomatitis and related lesions	0.745	0.254
G41 Status epilepticus	0.745	0.255
W00-W19 Falls	0.744	0.256
K05 Gingivitis and periodontal diseases	0.744	0.256
M91-M94 Chondropathies	0.744	0.256
O66 Other obstructed labour	0.743	0.257
O63.0 Prolonged first stage (of labour)	0.743	0.257
Y86 Sequelae of other accidents	0.741	0.259
L08.9 Local infection of skin and subcutaneous tissue, unspecified	0.739	0.261
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.739	0.261
C15.9 Oesophagus, unspecified	0.739	0.261
O36.0 Maternal care for rhesus isoimmunisation	0.738	0.262
I72 Other aneurysm	0.738	0.262
B25-B34 Other viral diseases	0.738	0.262
C16 Malignant neoplasm of stomach	0.737	0.263
I50.0 Congestive heart failure	0.735	0.265
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.734	0.265
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.734	0.266
G44 Other headache syndromes	0.733	0.267
J43.9 Emphysema, unspecified	0.733	0.267
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.732	0.268
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.730	0.270
O20.0 Threatened abortion	0.729	0.271
K02 Dental caries	0.728	0.271
O23 Infections of genito-urinary tract in pregnancy	0.728	0.272
O21 Excessive vomiting in pregnancy	0.728	0.272
G00-G09 Inflammatory diseases of the central nervous system	0.727	0.273
Y83.2 Surgical operation with anastomosis, bypass or graft	0.727	0.273
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.727	0.273
I47 Paroxysmal tachycardia	0.726	0.274
J18.9 Pneumonia, unspecified	0.726	0.274
M75.5 Bursitis of shoulder	0.726	0.274
M70 Soft tissue disorders related to use, overuse and pressure	0.725	0.275
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.725	0.275
I46 Cardiac arrest	0.725	0.275
I35.1 Aortic (valve) insufficiency	0.725	0.275
Chapter V Mental and behavioural disorders	0.725	0.275
I77.1 Stricture of artery	0.724	0.276
O30 Multiple gestation	0.724	0.276
E40-E46 Malnutrition	0.724	0.276
B35-B49 Mycoses	0.723	0.277
H90-H95 Other disorders of ear	0.723	0.277
M79.66 Pain in limb (Lower leg)	0.722	0.278
E87.1 Hypo-osmolality and hyponatraemia	0.722	0.278
S00-S09 Injuries to the head	0.721	0.278
L03.2 Cellulitis of face	0.721	0.279
O69 Labour and delivery complicated by umbilical cord complications	0.721	0.279
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.720	0.280
L08.8 Other specified local infections of skin and subcutaneous tissue	0.720	0.280
K55-K64 Other diseases of intestines	0.719	0.281
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.718	0.282
G70-G73 Diseases of myoneural junction and muscle	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
O85-O92 Complications predominantly related to the puerperium	0.717	0.283
L73 Other follicular disorders	0.717	0.283
C51-C58 Malignant neoplasms of female genital organs	0.716	0.284
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.716	0.284
O46 Antepartum haemorrhage, not elsewhere classified	0.716	0.284
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.715	0.285
K77 Liver disorders in diseases classified elsewhere	0.715	0.285
K73 Chronic hepatitis, not elsewhere classified	0.715	0.285
K71 Toxic liver disease	0.715	0.285
E86 Volume depletion	0.715	0.285
M60-M63 Disorders of muscles	0.714	0.286
M00-M03 Infectious arthropathies	0.714	0.286
M19.0 Primary arthrosis of other joints	0.714	0.286
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.713	0.286
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.713	0.287
L10-L14 Bullous disorders	0.713	0.287
Y83.9 Surgical procedure, unspecified	0.713	0.287
T33-T35 Frostbite	0.713	0.287
T26-T28 Burns and corrosions confined to eye and internal organs	0.713	0.287
T20-T25 Burns and corrosions of external body surface, specified by site	0.713	0.287
T00-T07 Injuries involving multiple body regions	0.713	0.287
S10-S19 Injuries to the neck	0.713	0.287
W20-W49 Exposure to inanimate mechanical forces	0.713	0.287
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.713	0.287
V20-V29 Motorcycle rider injured in transport accident	0.712	0.288
O36.8 Maternal care for other specified foetal problems	0.712	0.288
M19.96 Arthrosis, unspecified-Lower leg	0.711	0.289
O74 Complications of anaesthesia during labour and delivery	0.710	0.290
O73 Retained placenta and membranes, without haemorrhage	0.710	0.290
O71 Other obstetric trauma	0.710	0.290
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.710	0.290
O65 Obstructed labour due to maternal pelvic abnormality	0.710	0.290
O61 Failed induction of labour	0.710	0.290
O60 Preterm delivery	0.710	0.290
I00-I02 Acute rheumatic fever	0.710	0.290
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.710	0.290
Y35-Y36 Legal intervention and operations of war	0.710	0.290
Y10-Y34 Event of undetermined intent	0.710	0.290
Y00-Y09 Assault	0.710	0.290
X85-X99 Assault	0.710	0.290
X58-X59 Accidental exposure to other and unspecified factors	0.710	0.290
X50-X57 Overexertion, travel and privation	0.710	0.290
X40-X49 Accidental poisoning by and exposure to noxious substances	0.710	0.290
X30-X39 Exposure to forces of nature	0.710	0.290
X20-X29 Contact with venomous animals and plants	0.710	0.290
X10-X19 Contact with heat and hot substances	0.710	0.290
X00-X09 Exposure to smoke, fire and flames	0.710	0.290
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.710	0.290
W75-W84 Other accidental threats to breathing	0.710	0.290
W65-W74 Accidental drowning and submersion	0.710	0.290
W50-W64 Exposure to animate mechanical forces	0.710	0.290
V98-V99 Other and unspecified transport accidents	0.710	0.290
V95-V97 Air and space transport accidents	0.710	0.290
V90-V94 Water transport accidents	0.710	0.290
V70-V79 Bus occupant injured in transport accident	0.710	0.290
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.710	0.290
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.710	0.290
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.710	0.290
V01-V09 Pedestrian injured in transport accident	0.710	0.290
K83.8 Other specified diseases of biliary tract	0.709	0.290
L28 Lichen simplex chronicus and prurigo	0.709	0.291
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.708	0.292
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.708	0.292
G43 Migraine	0.708	0.292
T90 Sequelae of injuries of head	0.707	0.293
O45 Premature separation of placenta [abruptio placentae]	0.706	0.293
O44 Placenta praevia	0.706	0.293
O43 Placental disorders	0.706	0.293
O41 Other disorders of amniotic fluid and membranes	0.706	0.293
O35 Maternal care for known or suspected foetal abnormality and damage	0.706	0.293
O33 Maternal care for known or suspected disproportion	0.706	0.293
O31 Complications specific to multiple gestation	0.706	0.293
O40 Polyhydramnios	0.706	0.293
K13 Other diseases of lip and oral mucosa	0.705	0.294
C22.1 Intrahepatic bile duct carcinoma	0.705	0.295
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.705	0.295
C83 Diffuse non-Hodgkin's lymphoma	0.704	0.296
G81.9 Hemiplegia, unspecified	0.704	0.296
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.704	0.296
A80-A89 Viral infections of the central nervous system	0.704	0.296
T78 Adverse effects, not elsewhere classified	0.704	0.296
K76.7 Hepatorenal syndrome	0.703	0.297
K76.5 Hepatic veno-occlusive disease	0.703	0.297
K76.4 Peliosis hepatis	0.703	0.297
K76.3 Infarction of liver	0.703	0.297
K76.2 Central haemorrhagic necrosis of liver	0.703	0.297
K76.1 Chronic passive congestion of liver	0.703	0.297
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.702	0.298
S22 Fracture of rib(s), sternum and thoracic spine	0.700	0.299
J60-J70 Lung diseases due to external agents	0.700	0.300
K11.2 Sialoadenitis	0.699	0.301
O80-O84 Delivery	0.699	0.301
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.699	0.301
E83.5 Disorders of calcium metabolism	0.698	0.302
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.698	0.302
Y40 Systemic antibiotics	0.698	0.302
L71 Rosacea	0.697	0.303
M79.65 Pain in limb (Pelvic region and thigh)	0.696	0.304
D63 Anaemia in chronic diseases classified elsewhere	0.696	0.304
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.695	0.305
C40-C41 Malignant neoplasms of bone and articular cartilage	0.695	0.305
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.695	0.305
Y43 Primarily systemic agents	0.695	0.305
K86.0 Alcohol-induced chronic pancreatitis	0.695	0.305
C79.6 Secondary malignant neoplasm of ovary	0.695	0.305
G46 Vascular syndromes of brain in cerebrovascular diseases	0.693	0.306
J20 Acute bronchitis	0.693	0.307
Chapter XXII Codes for special purposes	0.693	0.307
Chapter XXI Factors influencing health status and contact with health services	0.692	0.308
B02 Zoster [herpes zoster]	0.691	0.309
M35 Other systemic involvement of connective tissue	0.691	0.309
E27 Other disorders of adrenal gland	0.690	0.309
O70 Perineal laceration during delivery	0.690	0.310
Y57 Other and unspecified drugs and medicaments	0.690	0.310
H61.2 Impacted cerumen	0.689	0.311
O48 Prolonged pregnancy	0.689	0.311
Y60-Y69 Misadventures to patients during surgical and medical care	0.689	0.311
E87.0 Hyperosmolality and hypernatraemia	0.689	0.311
O29 Complications of anaesthesia during pregnancy	0.688	0.312
O28 Abnormal findings on antenatal screening of mother	0.688	0.312
O24 Diabetes mellitus in pregnancy	0.688	0.312
O22 Venous complications in pregnancy	0.688	0.312
O25 Malnutrition in pregnancy	0.688	0.312
E88 Other metabolic disorders	0.688	0.312
E85 Amyloidosis	0.688	0.312
E84 Cystic fibrosis	0.688	0.312
E79 Disorders of purine and pyrimidine metabolism	0.688	0.312
E77 Disorders of glycoprotein metabolism	0.688	0.312
E76 Disorders of glycosaminoglycan metabolism	0.688	0.312
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.688	0.312
E74 Other disorders of carbohydrate metabolism	0.688	0.312
E73 Lactose intolerance	0.688	0.312
E72 Other disorders of amino-acid metabolism	0.688	0.312
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.688	0.312
E70 Disorders of aromatic amino-acid metabolism	0.688	0.312
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.688	0.312
K80.8 Other cholelithiasis	0.688	0.312
B97 Viral agents as the cause of diseases classified to other chapters	0.687	0.312
K74.0 Hepatic fibrosis	0.687	0.313
I49.0 Ventricular fibrillation and flutter	0.686	0.314
K72 Hepatic failure, not elsewhere classified	0.686	0.314
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.685	0.315
I95-I99 Other and unspecified disorders of the circulatory system	0.685	0.315
B07 Viral warts	0.685	0.315
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.684	0.315
E87.4 Mixed disorder of acid-base balance	0.684	0.315
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.684	0.316
K70.2 Alcoholic fibrosis and sclerosis of liver	0.684	0.316
K70.1 Alcoholic hepatitis	0.684	0.316
K70.0 Alcoholic fatty liver	0.684	0.316
O00-O08 Pregnancy with abortive outcome	0.684	0.316
K10 Other diseases of jaws	0.683	0.316
K06 Other disorders of gingiva and edentulous alveolar ridge	0.683	0.316
K03 Other diseases of hard tissues of teeth	0.683	0.316
K00 Disorders of tooth development and eruption	0.683	0.316
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters	0.683	0.316
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.683	0.317
I68 Cerebrovascular disorders in diseases classified elsewhere	0.683	0.317
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.683	0.317
G40.7 Petit mal, unspecified, without grand mal seizures	0.682	0.318
G40.5 Special epileptic syndromes	0.682	0.318
G40.4 Other generalised epilepsy and epileptic syndromes	0.682	0.318
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.682	0.318
T98 Sequelae of other and unspecified effects of external causes	0.682	0.318
T95 Sequelae of burns, corrosions and frostbite	0.682	0.318
T94 Sequelae of injuries involving multiple and unspecified body regions	0.682	0.318
T91 Sequelae of injuries of neck and trunk	0.682	0.318
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.682	0.318
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.682	0.318
X60-X84 Intentional self-harm	0.682	0.318
K65 Peritonitis	0.682	0.318
M22.4 Chondromalacia patellae	0.681	0.318
L80-L99 Other disorders of the skin and subcutaneous tissue	0.682	0.318
M53 Other dorsopathies, not elsewhere classified	0.681	0.319
K85 Acute pancreatitis	0.680	0.319
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.680	0.320
O20.9 Haemorrhage in early pregnancy, unspecified	0.680	0.320
B15-B19 Viral hepatitis	0.680	0.320
S90-S99 Injuries to the ankle and foot	0.680	0.320
L40-L45 Papulosquamous disorders	0.680	0.320
K07 Dentofacial anomalies [including malocclusion]	0.679	0.320
G24 Dystonia	0.679	0.321
E80 Disorders of porphyrin and bilirubin metabolism	0.679	0.321
O47.1 False labour at or after 37 completed weeks of gestation	0.679	0.321
O75.2 Pyrexia during labour, not elsewhere classified	0.678	0.322
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.678	0.322
O97 Death from sequelae of direct obstetric causes	0.678	0.322
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.678	0.322
O95 Obstetric death of unspecified cause	0.678	0.322
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.678	0.322
B99-B99 Other infectious diseases	0.678	0.322
B90-B94 Sequelae of infectious and parasitic diseases	0.678	0.322
B85-B89 Pediculosis, acariasis and other infestations	0.678	0.322
B65-B83 Helminthiases	0.678	0.322
B50-B64 Protozoal diseases	0.678	0.322
B20-B24 Human immunodeficiency virus [HIV] disease	0.678	0.322
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.678	0.322
A75-A79 Rickettsioses	0.678	0.322
A70-A74 Other diseases caused by chlamydiae	0.678	0.322
A65-A69 Other spirochaetal diseases	0.678	0.322
A20-A28 Certain zoonotic bacterial diseases	0.678	0.322
A15-A19 Tuberculosis	0.678	0.322
M15 Polyarthrosis	0.676	0.324
J90-J94 Other diseases of pleura	0.675	0.325
H80-H83 Diseases of inner ear	0.675	0.325
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.674	0.325
I62 Other nontraumatic intracranial haemorrhage	0.674	0.326
Y83.3 Surgical operation with formation of external stoma	0.674	0.326
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.673	0.327
M84 Disorders of continuity of bone	0.673	0.327
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.673	0.327
K90-K93 Other diseases of the digestive system	0.672	0.328
J18.1 Lobar pneumonia, unspecified	0.672	0.328
D45 Polycythaemia vera	0.671	0.329
C71 Malignant neoplasm of brain	0.671	0.329
M25.5 Pain in joint	0.671	0.329
L75 Apocrine sweat disorders	0.671	0.329
L74 Eccrine sweat disorders	0.671	0.329
L70 Acne	0.671	0.329
L68 Hypertrichosis	0.671	0.329
L67 Hair colour and hair shaft abnormalities	0.671	0.329
L66 Cicatricial alopecia [scarring hair loss]	0.671	0.329
L65 Other nonscarring hair loss	0.671	0.329
L64 Androgenic alopecia	0.671	0.329
L63 Alopecia areata	0.671	0.329
L62 Nail disorders in diseases classified elsewhere	0.671	0.329
O36.5 Maternal care for poor foetal growth	0.670	0.330
H61.0 Perichondritis of external ear	0.670	0.330
D75 Other diseases of blood and blood-forming organs	0.670	0.330
Q61 Cystic kidney disease	0.669	0.331
L25 Unspecified contact dermatitis	0.669	0.331
L24 Irritant contact dermatitis	0.669	0.331
L23 Allergic contact dermatitis	0.669	0.331
L21 Seborrhoeic dermatitis	0.669	0.331
L20 Atopic dermatitis	0.669	0.331
L26 Exfoliative dermatitis	0.669	0.331
L22 Diaper [napkin] dermatitis	0.669	0.331
I67.9 Cerebrovascular disease, unspecified	0.669	0.331
I31 Other diseases of pericardium	0.669	0.331
D55-D59 Haemolytic anaemias	0.669	0.331
O63.9 Long labour, unspecified	0.668	0.332
M21 Other acquired deformities of limbs	0.668	0.332
M76 Enthesopathies of lower limb, excluding foot	0.667	0.333
M73 Soft tissue disorders in diseases classified elsewhere	0.667	0.333
C22.9 Liver, unspecified	0.667	0.333
G25 Other extrapyramidal and movement disorders	0.667	0.333
C26 Malignant neoplasm of other and ill-defined digestive organs	0.667	0.333
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.667	0.333
C21 Malignant neoplasm of anus and anal canal	0.667	0.333
C17 Malignant neoplasm of small intestine	0.667	0.333
C23 Malignant neoplasm of gallbladder	0.667	0.333
M54.1 Radiculopathy	0.667	0.333
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.666	0.334
O63.2 Delayed delivery of second twin, triplet, etc.	0.666	0.334

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations