TreeWAS – Variant ID: rs72705699

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XX External causes of morbidity and mortality	1.000	0.000
Chapter XV Pregnancy, childbirth and the puerperium	1.000	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	1.000	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.998	0.002
Chapter XII Diseases of the skin and subcutaneous tissue	0.998	0.002
Chapter IV Endocrine, nutritional and metabolic diseases	0.998	0.002
Chapter VII Diseases of the eye and adnexa	0.998	0.002
Y43 Primarily systemic agents	0.994	0.006
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.992	0.008
H02 Other disorders of eyelid	0.990	0.010
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.988	0.012
Y43.3 Other antineoplastic drugs	0.988	0.012
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.985	0.015
O60-O75 Complications of labour and delivery	0.984	0.016
H04 Disorders of lachrymal system	0.983	0.017
D70-D77 Other diseases of blood and blood-forming organs	0.981	0.019
D70 Agranulocytosis	0.978	0.022
E70-E90 Metabolic disorders	0.973	0.027
L00-L08 Infections of the skin and subcutaneous tissue	0.973	0.027
H02.3 Blepharochalasis	0.968	0.032
L03 Cellulitis	0.951	0.049
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.947	0.053
H02.0 Entropion and trichiasis of eyelid	0.938	0.062
E10-E14 Diabetes mellitus	0.935	0.065
H04.5 Stenosis and insufficiency of lachrymal passages	0.934	0.066
H55-H59 Other disorders of eye and adnexa	0.932	0.068
Y52 Agents primarily affecting the cardiovascular system	0.929	0.071
E20-E35 Disorders of other endocrine glands	0.927	0.073
W20-W49 Exposure to inanimate mechanical forces	0.926	0.074
E87 Other disorders of fluid, electrolyte and acid-base balance	0.923	0.077
O68 Labour and delivery complicated by foetal stress [distress]	0.922	0.078
L80-L99 Other disorders of the skin and subcutaneous tissue	0.922	0.078
O72 Postpartum haemorrhage	0.911	0.089
S20-S29 Injuries to the thorax	0.909	0.091
O20-O29 Other maternal disorders predominantly related to pregnancy	0.908	0.092
L40-L45 Papulosquamous disorders	0.906	0.094
Chapter I Certain infectious and parasitic diseases	0.906	0.094
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.897	0.103
A30-A49 Other bacterial diseases	0.896	0.104
H04.2 Epiphora	0.894	0.106
W00-W19 Falls	0.894	0.106
O72.1 Other immediate postpartum haemorrhage	0.889	0.111
A41 Other septicaemia	0.887	0.113
A41.9 Septicaemia, unspecified	0.879	0.121
T20-T25 Burns and corrosions of external body surface, specified by site	0.878	0.122
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.876	0.124
O34 Maternal care for known or suspected abnormality of pelvic organs	0.869	0.131
T15-T19 Effects of foreign body entering through natural orifice	0.869	0.131
T66-T78 Other and unspecified effects of external causes	0.867	0.133
O40 Polyhydramnios	0.863	0.137
S90-S99 Injuries to the ankle and foot	0.861	0.139
Y52.4 Angiotensin-converting-enzyme inhibitors	0.860	0.140
H01 Other inflammation of eyelid	0.859	0.141
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.857	0.143
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.856	0.144
L40 Psoriasis	0.854	0.146
L03.8 Cellulitis of other sites	0.851	0.149
L03.2 Cellulitis of face	0.849	0.151
E10 Insulin-dependent diabetes mellitus	0.846	0.154
E87.1 Hypo-osmolality and hyponatraemia	0.846	0.154
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.844	0.156
E87.5 Hyperkalaemia	0.844	0.156
L05 Pilonidal cyst	0.843	0.157
E11 Non-insulin-dependent diabetes mellitus	0.843	0.157
H57 Other disorders of eye and adnexa	0.841	0.159
E86 Volume depletion	0.839	0.161
S22 Fracture of rib(s), sternum and thoracic spine	0.839	0.161
L92 Granulomatous disorders of skin and subcutaneous tissue	0.839	0.161
H02.4 Ptosis of eyelid	0.836	0.164
O20 Haemorrhage in early pregnancy	0.835	0.165
O46 Antepartum haemorrhage, not elsewhere classified	0.832	0.168
E50-E64 Other nutritional deficiencies	0.830	0.170
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.830	0.170
E83 Disorders of mineral metabolism	0.829	0.171
Y46 Antiepileptics and anti-Parkinsonism drugs	0.828	0.172
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.825	0.175
S70-S79 Injuries to the hip and thigh	0.822	0.178
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.821	0.179
H05 Disorders of orbit	0.820	0.180
O48 Prolonged pregnancy	0.819	0.181
H02.2 Lagophthalmos	0.817	0.183
S60-S69 Injuries to the wrist and hand	0.817	0.183
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.816	0.184
L84 Corns and callosities	0.813	0.187
Y60-Y69 Misadventures to patients during surgical and medical care	0.812	0.188
W25 Contact with sharp glass	0.810	0.190
O36 Maternal care for other known or suspected foetal problems	0.809	0.191
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.807	0.192
L95 Vasculitis limited to skin, not elsewhere classified	0.805	0.195
Y43.0 Antiallergic and antiemetic drugs	0.805	0.195
D80-D89 Certain disorders involving the immune mechanism	0.801	0.199
O62 Abnormalities of forces of labour	0.800	0.200
W19 Unspecified fall	0.799	0.201
L50-L54 Urticaria and erythema	0.799	0.201
W50-W64 Exposure to animate mechanical forces	0.796	0.203
Y57 Other and unspecified drugs and medicaments	0.796	0.204
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.794	0.206
O85-O92 Complications predominantly related to the puerperium	0.793	0.207
E87.2 Acidosis	0.793	0.207
E21.0 Primary hyperparathyroidism	0.792	0.208
L94 Other localised connective tissue disorders	0.787	0.213
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.787	0.213
L03.1 Cellulitis of other parts of limb	0.785	0.215
O94-O99 Other obstetric conditions, not elsewhere classified	0.784	0.216
S27 Injury of other and unspecified intrathoracic organs	0.782	0.218
D73 Diseases of spleen	0.781	0.219
L03.3 Cellulitis of trunk	0.780	0.220
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.780	0.220
E11.5 With peripheral circulatory complications	0.780	0.220
T79-T79 Certain early complications of trauma	0.779	0.221
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.779	0.221
Y43.4 Immunosuppressive agents	0.777	0.223
L40.9 Psoriasis, unspecified	0.773	0.227
D72 Other disorders of white blood cells	0.773	0.227
O73 Retained placenta and membranes, without haemorrhage	0.773	0.227
O34.2 Maternal care due to uterine scar from previous surgery	0.770	0.230
S22.0 Fracture of thoracic vertebra	0.770	0.230
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.768	0.232
E10.5 With peripheral circulatory complications	0.768	0.232
Y00-Y09 Assault	0.767	0.233
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.767	0.233
O71 Other obstetric trauma	0.766	0.234
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.766	0.234
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.766	0.234
H57.1 Ocular pain	0.766	0.234
Y40 Systemic antibiotics	0.763	0.237
S40-S49 Injuries to the shoulder and upper arm	0.762	0.238
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.760	0.239
T18 Foreign body in alimentary tract	0.759	0.240
O80-O84 Delivery	0.757	0.243
E16 Other disorders of pancreatic internal secretion	0.756	0.244
O20.0 Threatened abortion	0.756	0.244
O47 False labour	0.756	0.244
E85 Amyloidosis	0.755	0.245
T78 Adverse effects, not elsewhere classified	0.754	0.246
W44 Foreign body entering into or through eye or natural orifice	0.754	0.246
E55 Vitamin D deficiency	0.753	0.246
O42 Premature rupture of membranes	0.752	0.248
Chapter XXII Codes for special purposes	0.751	0.249
H01.0 Blepharitis	0.751	0.249
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.751	0.249
L05.9 Pilonidal cyst without abscess	0.751	0.249
O32 Maternal care for known or suspected malpresentation of foetus	0.750	0.249
H04.1 Other disorders of lachrymal gland	0.750	0.250
H04.9 Disorder of lachrymal system, unspecified	0.749	0.251
Q80-Q89 Other congenital malformations	0.749	0.251
E74 Other disorders of carbohydrate metabolism	0.749	0.251
H00 Hordeolum and chalazion	0.748	0.252
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.746	0.253
L03.9 Cellulitis, unspecified	0.744	0.256
S50-S59 Injuries to the elbow and forearm	0.743	0.257
O64 Obstructed labour due to malposition and malpresentation of foetus	0.741	0.259
B35-B49 Mycoses	0.741	0.259
S91 Open wound of ankle and foot	0.739	0.261
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.739	0.261
Y41 Other systemic anti-infectives and antiparasitics	0.739	0.261
E20 Hypoparathyroidism	0.737	0.262
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.736	0.264
W22 Striking against or struck by other objects	0.735	0.265
L93 Lupus erythematosus	0.735	0.265
H10-H13 Disorders of conjunctiva	0.735	0.265
H06.2 Dysthyroid exophthalmos	0.734	0.266
T00-T07 Injuries involving multiple body regions	0.733	0.267
H55 Nystagmus and other irregular eye movements	0.733	0.267
V20-V29 Motorcycle rider injured in transport accident	0.730	0.270
W49 Exposure to other and unspecified inanimate mechanical forces	0.729	0.271
Y51 Drugs primarily affecting the autonomic nervous system	0.728	0.272
W25.9 Unspecified place	0.726	0.274
O35 Maternal care for known or suspected foetal abnormality and damage	0.726	0.274
T23 Burn and corrosion of wrist and hand	0.726	0.274
L40.0 Psoriasis vulgaris	0.724	0.276
L20-L30 Dermatitis and eczema	0.724	0.276
V40-V49 Car occupant injured in transport accident	0.722	0.278
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.722	0.278
L95.9 Vasculitis limited to skin, unspecified	0.721	0.279
S22.4 Multiple fractures of ribs	0.721	0.279
S22.00 Fracture of thoracic vertebra (closed)	0.721	0.279
A41.8 Other specified septicaemia	0.721	0.279
Q38-Q45 Other congenital malformations of the digestive system	0.721	0.279
O61 Failed induction of labour	0.720	0.280
O46.9 Antepartum haemorrhage, unspecified	0.720	0.280
X50-X57 Overexertion, travel and privation	0.720	0.280
S10-S19 Injuries to the neck	0.719	0.281
S90 Superficial injury of ankle and foot	0.718	0.282
V80-V89 Other land transport accidents	0.718	0.282
E27 Other disorders of adrenal gland	0.718	0.282
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
Y35-Y36 Legal intervention and operations of war	0.717	0.283
Y10-Y34 Event of undetermined intent	0.717	0.283
X85-X99 Assault	0.717	0.283
X58-X59 Accidental exposure to other and unspecified factors	0.717	0.283
X30-X39 Exposure to forces of nature	0.717	0.283
X10-X19 Contact with heat and hot substances	0.717	0.283
X00-X09 Exposure to smoke, fire and flames	0.717	0.283
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.717	0.283
W75-W84 Other accidental threats to breathing	0.717	0.283
W65-W74 Accidental drowning and submersion	0.717	0.283
V98-V99 Other and unspecified transport accidents	0.717	0.283
V95-V97 Air and space transport accidents	0.717	0.283
V90-V94 Water transport accidents	0.717	0.283
V70-V79 Bus occupant injured in transport accident	0.717	0.283
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.717	0.283
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.717	0.283
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.717	0.283
V01-V09 Pedestrian injured in transport accident	0.717	0.283
O43 Placental disorders	0.717	0.283
Y59 Other and unspecified vaccines and biological substances	0.717	0.283
Y58 Bacterial vaccines	0.717	0.283
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.717	0.283
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.717	0.283
Y53 Agents primarily affecting the gastro-intestinal system	0.717	0.283
Y50 Central nervous system stimulants, not elsewhere classified	0.717	0.283
Y49 Psychotropic drugs, not elsewhere classified	0.717	0.283
Y48 Anaesthetics and therapeutic gases	0.717	0.283
Y47 Sedatives, hypnotics and antianxiety drugs	0.717	0.283
O36.5 Maternal care for poor foetal growth	0.716	0.284
H03 Disorders of eyelid in diseases classified elsewhere	0.716	0.284
O75 Other complications of labour and delivery, not elsewhere classified	0.716	0.284
L10-L14 Bullous disorders	0.715	0.285
T20 Burn and corrosion of head and neck	0.715	0.285
V10-V19 Pedal cyclist injured in transport accident	0.715	0.285
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.713	0.287
Y43.9 Primarily systemic agent, unspecified	0.713	0.287
Y43.8 Other primarily systemic agents, not elsewhere classified	0.713	0.287
Y43.6 Enzymes, not elsewhere classified	0.713	0.287
Y43.5 Acidifying and alkalising agents	0.713	0.287
Y43.2 Antineoplastic natural products	0.713	0.287
E28 Ovarian dysfunction	0.713	0.287
T33-T35 Frostbite	0.711	0.289
T26-T28 Burns and corrosions confined to eye and internal organs	0.711	0.289
Q00-Q07 Congenital malformations of the nervous system	0.711	0.289
H02.7 Other degenerative disorders of eyelid and periocular area	0.710	0.290
O45 Premature separation of placenta [abruptio placentae]	0.708	0.292
O33 Maternal care for known or suspected disproportion	0.708	0.292
O31 Complications specific to multiple gestation	0.708	0.292
A46 Erysipelas	0.707	0.292
B25-B34 Other viral diseases	0.707	0.293
D55-D59 Haemolytic anaemias	0.706	0.293
Chapter XXI Factors influencing health status and contact with health services	0.706	0.294
O74 Complications of anaesthesia during labour and delivery	0.705	0.295
O65 Obstructed labour due to maternal pelvic abnormality	0.705	0.295
O60 Preterm delivery	0.705	0.295
H04.8 Other disorders of lachrymal system	0.705	0.295
H04.6 Other changes in lachrymal passages	0.705	0.295
H04.4 Chronic inflammation of lachrymal passages	0.705	0.295
H04.3 Acute and unspecified inflammation of lachrymal passages	0.705	0.295
H04.0 Dacryoadenitis	0.705	0.295
Y46.2 Hydantoin derivatives	0.705	0.295
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.704	0.295
O44 Placenta praevia	0.704	0.296
E83.1 Disorders of iron metabolism	0.704	0.296
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.703	0.297
D74 Methaemoglobinaemia	0.703	0.297
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.703	0.297
D71 Functional disorders of polymorphonuclear neutrophils	0.703	0.297
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.703	0.297
Y43.1 Antineoplastic antimetabolites	0.700	0.300
Z37 Outcome of delivery	0.699	0.301
E55.9 Vitamin D deficiency, unspecified	0.699	0.301
Z37.0 Single live birth	0.699	0.301
W06 Fall involving bed	0.698	0.302
H46-H48 Disorders of optic nerve and visual pathways	0.698	0.302
E11.2 With renal complications	0.698	0.302
E84 Cystic fibrosis	0.698	0.302
E79 Disorders of purine and pyrimidine metabolism	0.698	0.302
E77 Disorders of glycoprotein metabolism	0.698	0.302
E76 Disorders of glycosaminoglycan metabolism	0.698	0.302
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.698	0.302
E72 Other disorders of amino-acid metabolism	0.698	0.302
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.698	0.302
E70 Disorders of aromatic amino-acid metabolism	0.698	0.302
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.698	0.302
L04 Acute lymphadenitis	0.698	0.302
L01 Impetigo	0.698	0.302
L00 Staphylococcal scalded skin syndrome	0.698	0.302
E40-E46 Malnutrition	0.695	0.304
H02.6 Xanthelasma of eyelid	0.695	0.305
X20-X29 Contact with venomous animals and plants	0.694	0.306
H05.2 Exophthalmic conditions	0.694	0.306
E13 Other specified diabetes mellitus	0.692	0.307
A48 Other bacterial diseases, not elsewhere classified	0.692	0.308
D86 Sarcoidosis	0.691	0.309
A50-A64 Infections with a predominantly sexual mode of transmission	0.690	0.310
O23 Infections of genito-urinary tract in pregnancy	0.688	0.312
E10.4 With neurological complications	0.687	0.313
X60-X84 Intentional self-harm	0.687	0.313
E11.3 With ophthalmic complications	0.686	0.314
E16.2 Hypoglycaemia, unspecified	0.684	0.316
S64 Injury of nerves at wrist and hand level	0.684	0.316
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.683	0.316
X40-X49 Accidental poisoning by and exposure to noxious substances	0.683	0.317
L97 Ulcer of lower limb, not elsewhere classified	0.683	0.317
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.683	0.317
E88 Other metabolic disorders	0.682	0.318
O24 Diabetes mellitus in pregnancy	0.681	0.318
T18.1 Foreign body in oesophagus	0.681	0.319
S62 Fracture at wrist and hand level	0.681	0.319
O15 Eclampsia	0.679	0.321
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.679	0.321
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.679	0.321
A40 Streptococcal septicaemia	0.678	0.322
E73 Lactose intolerance	0.677	0.323
O63 Long labour	0.677	0.323
E22 Hyperfunction of pituitary gland	0.676	0.323
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.675	0.324
T31 Burns classified according to extent of body surface involved	0.675	0.325
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.674	0.326
O20.8 Other haemorrhage in early pregnancy	0.674	0.326
T68 Hypothermia	0.672	0.328
E12 Malnutrition-related diabetes mellitus	0.670	0.330
W19.2 School, other institution and public administrative area	0.670	0.330
T17 Foreign body in respiratory tract	0.669	0.331
W07 Fall involving chair	0.668	0.332
E21.3 Hyperparathyroidism, unspecified	0.667	0.333
E34 Other endocrine disorders	0.666	0.334
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.666	0.334
Y52.8 Antivaricose drugs, including sclerosing agents	0.666	0.334
Y52.7 Peripheral vasodilators	0.666	0.334
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.666	0.334
Y52.1 Calcium-channel blockers	0.666	0.334
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.666	0.334
L08 Other local infections of skin and subcutaneous tissue	0.665	0.335
E10.8 With unspecified complications	0.665	0.335
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.665	0.335
E35 Disorders of endocrine glands in diseases classified elsewhere	0.664	0.336
E32 Diseases of thymus	0.664	0.336
E31 Polyglandular dysfunction	0.664	0.336
E30 Disorders of puberty, not elsewhere classified	0.664	0.336
E26 Hyperaldosteronism	0.664	0.336
E25 Adrenogenital disorders	0.664	0.336
E24 Cushing's syndrome	0.664	0.336
L50 Urticaria	0.664	0.336
W46 Contact with hypodermic needle	0.664	0.336
W45 Foreign body or object entering through skin	0.664	0.336
W43 Exposure to vibration	0.664	0.336
W42 Exposure to noise	0.664	0.336
W41 Exposure to high-pressure jet	0.664	0.336
W40 Explosion of other materials	0.664	0.336
W39 Discharge of firework	0.664	0.336
W38 Explosion and rupture of other specified pressurised devices	0.664	0.336
W37 Explosion and rupture of pressurised tyre, pipe or hose	0.664	0.336
W36 Explosion and rupture of gas cylinder	0.664	0.336
W35 Explosion and rupture of boiler	0.664	0.336
W34 Discharge from other and unspecified firearms	0.664	0.336
W33 Rifle, shotgun and larger firearm discharge	0.664	0.336
W32 Handgun discharge	0.664	0.336
W31 Contact with other and unspecified machinery	0.664	0.336
W30 Contact with agricultural machinery	0.664	0.336
W28 Contact with powered lawn mower	0.664	0.336
W27 Contact with nonpowered hand tool	0.664	0.336
W26 Contact with knife, sword or dagger	0.664	0.336
W24 Contact with lifting and transmission devices, not elsewhere classified	0.664	0.336
W23 Caught, crushed, jammed or pinched in or between objects	0.664	0.336
W21 Striking against or struck by sports equipment	0.664	0.336
W20 Struck by thrown, projected or falling object	0.664	0.336
Chapter VIII Diseases of the ear and mastoid process	0.663	0.337
O41 Other disorders of amniotic fluid and membranes	0.662	0.338
E87.4 Mixed disorder of acid-base balance	0.662	0.338
E87.3 Alkalosis	0.662	0.338
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.661	0.339
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.661	0.339
L87 Transepidermal elimination disorders	0.661	0.339
L88 Pyoderma gangrenosum	0.661	0.339
L86 Keratoderma in diseases classified elsewhere	0.661	0.339
L80 Vitiligo	0.661	0.339
H02.8 Other specified disorders of eyelid	0.661	0.339
E10.3 With ophthalmic complications	0.661	0.339
O82 Single delivery by Caesarean section	0.661	0.339
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.660	0.340
W19.9 Unspecified place	0.659	0.341
S70 Superficial injury of hip and thigh	0.659	0.341
O21 Excessive vomiting in pregnancy	0.659	0.341
E11.6 With other specified complications	0.658	0.341
E83.3 Disorders of phosphorus metabolism	0.658	0.342
O34.1 Maternal care for tumour of corpus uteri	0.657	0.343
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.657	0.343
W60 Contact with plant thorns and spines and sharp leaves	0.656	0.344
E29 Testicular dysfunction	0.655	0.344
W18 Other fall on same level	0.655	0.345
O16 Unspecified maternal hypertension	0.655	0.345
O72.3 Postpartum coagulation defects	0.653	0.346
O30 Multiple gestation	0.652	0.348
S29 Other and unspecified injuries of thorax	0.652	0.348
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.652	0.348
S26 Injury of heart	0.652	0.348
S25 Injury of blood vessels of thorax	0.652	0.348
S24 Injury of nerves and spinal cord at thorax level	0.652	0.348
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.652	0.348
S21 Open wound of thorax	0.652	0.348
A41.0 Septicaemia due to Staphylococcus aureus	0.652	0.348
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.652	0.348
O29 Complications of anaesthesia during pregnancy	0.651	0.349
O28 Abnormal findings on antenatal screening of mother	0.651	0.349
O22 Venous complications in pregnancy	0.651	0.349
O25 Malnutrition in pregnancy	0.651	0.349
H57.9 Disorder of eye and adnexa, unspecified	0.651	0.349
S27.3 Other injuries of lung	0.651	0.349
E10.1 With ketoacidosis	0.651	0.349
T78.3 Angioneurotic oedema	0.650	0.350
L44 Other papulosquamous disorders	0.650	0.350
L41 Parapsoriasis	0.650	0.350
L45 Papulosquamous disorders in diseases classified elsewhere	0.650	0.350
L42 Pityriasis rosea	0.650	0.350
B99-B99 Other infectious diseases	0.649	0.351
B85-B89 Pediculosis, acariasis and other infestations	0.649	0.351
B50-B64 Protozoal diseases	0.649	0.351
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.649	0.351
A75-A79 Rickettsioses	0.649	0.351
A70-A74 Other diseases caused by chlamydiae	0.649	0.351
A65-A69 Other spirochaetal diseases	0.649	0.351
A20-A28 Certain zoonotic bacterial diseases	0.649	0.351
A15-A19 Tuberculosis	0.649	0.351
L94.9 Localised connective tissue disorder, unspecified	0.649	0.351
S68 Traumatic amputation of wrist and hand	0.647	0.353
E83.4 Disorders of magnesium metabolism	0.647	0.353
L85 Other epidermal thickening	0.645	0.355
Y45.0 Opioids and related analgesics	0.645	0.355
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.644	0.356
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.644	0.356
A44 Bartonellosis	0.643	0.357
A43 Nocardiosis	0.643	0.357
A42 Actinomycosis	0.643	0.357
A39 Meningococcal infection	0.643	0.357
A37 Whooping cough	0.643	0.357
A36 Diphtheria	0.643	0.357
A32 Listeriosis	0.643	0.357
A31 Infection due to other mycobacteria	0.643	0.357
A30 Leprosy [Hansen's disease]	0.643	0.357
A38 Scarlet fever	0.643	0.357
A35 Other tetanus	0.643	0.357
A34 Obstetrical tetanus	0.643	0.357
A33 Tetanus neonatorum	0.643	0.357
S50 Superficial injury of forearm	0.642	0.358
O62.3 Precipitate labour	0.642	0.358
L40.5 Arthropathic psoriasis	0.642	0.358
L81 Other disorders of pigmentation	0.641	0.358
W17 Other fall from one level to another	0.641	0.359
W16 Diving or jumping into water causing injury other than drowning or submersion	0.641	0.359
W15 Fall from cliff	0.641	0.359
W14 Fall from tree	0.641	0.359
W12 Fall on and from scaffolding	0.641	0.359
W11 Fall on and from ladder	0.641	0.359
W09 Fall involving playground equipment	0.641	0.359
W08 Fall involving other furniture	0.641	0.359
W05 Fall involving wheelchair	0.641	0.359
W04 Fall while being carried or supported by other persons	0.641	0.359
W03 Other fall on same level due to collision with, or pushing by, another person	0.641	0.359
W01 Fall on same level from slipping, tripping and stumbling	0.641	0.359
W00 Fall on same level involving ice and snow	0.641	0.359
S60 Superficial injury of wrist and hand	0.641	0.359
W13 Fall from, out of or through building or structure	0.638	0.362
W10 Fall on and from stairs and steps	0.638	0.362
B20-B24 Human immunodeficiency virus [HIV] disease	0.637	0.362
O66 Other obstructed labour	0.637	0.362
H58.8 Visual disturbances in diseases classified elsewhere	0.637	0.363
S22.40 Multiple fractures of ribs (closed)	0.637	0.363
Y54.5 Other diuretics	0.637	0.363
A41.4 Septicaemia due to anaerobes	0.636	0.364
A41.3 Septicaemia due to Haemophilus influenzae	0.636	0.364
A41.2 Septicaemia due to unspecified staphylococcus	0.636	0.364
Y57.9 Drug or medicament, unspecified	0.636	0.364
L60-L75 Disorders of skin appendages	0.636	0.364
B37 Candidiasis	0.635	0.365
S91.3 Open wound of other parts of foot	0.634	0.366
O69 Labour and delivery complicated by umbilical cord complications	0.634	0.366
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.633	0.367
H01.8 Other specified inflammation of eyelid	0.632	0.368
O70 Perineal laceration during delivery	0.631	0.369
E11.8 With unspecified complications	0.631	0.369
L94.2 Calcinosis cutis	0.631	0.369
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent	0.630	0.369
W44.0 Home	0.630	0.370
T25 Burn and corrosion of ankle and foot	0.629	0.370
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.629	0.370
T21 Burn and corrosion of trunk	0.629	0.370
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.629	0.371
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.628	0.372
Q35-Q37 Cleft lip and cleft palate	0.628	0.372
Q30-Q34 Congenital malformations of the respiratory system	0.628	0.372
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.628	0.372
T78.4 Allergy, unspecified	0.628	0.372
O86 Other puerperal infections	0.627	0.373
L29 Pruritus	0.627	0.373
T79 Certain early complications of trauma, not elsewhere classified	0.627	0.373
T92 Sequelae of injuries of upper limb	0.626	0.374
B65-B83 Helminthiases	0.625	0.375
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.625	0.375
D72.8 Other specified disorders of white blood cells	0.623	0.377
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.623	0.377
O34.8 Maternal care for other abnormalities of pelvic organs	0.623	0.377
O34.7 Maternal care for abnormality of vulva and perineum	0.623	0.377
O34.6 Maternal care for abnormality of vagina	0.623	0.377
O34.5 Maternal care for other abnormalities of gravid uterus	0.623	0.377
O34.4 Maternal care for other abnormalities of cervix	0.623	0.377
O34.3 Maternal care for cervical incompetence	0.623	0.377
O34.0 Maternal care for congenital malformation of uterus	0.623	0.377
S41 Open wound of shoulder and upper arm	0.623	0.377
T19 Foreign body in genito-urinary tract	0.623	0.377
T15 Foreign body on external eye	0.623	0.377

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations