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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs72725317
log Bayes Factor = 24.9449
Chromosome 1   position 102,996,034  (GRCh37) Explore rs72725317 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
Chapter I Certain infectious and parasitic diseases
0.998 0.002 0.000
Chapter XXI Factors influencing health status and contact with health services
0.998 0.002 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.997 0.003 0.000
E70-E90 Metabolic disorders
0.995 0.005 0.000
M15-M19 Arthrosis
0.995 0.005 0.000
Chapter X Diseases of the respiratory system
0.995 0.005 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.994 0.006 0.000
Chapter VI Diseases of the nervous system
0.990 0.010 0.000
E10-E14 Diabetes mellitus
0.989 0.011 0.000
M16 Coxarthrosis [arthrosis of hip]
0.984 0.016 0.000
M16.9 Coxarthrosis, unspecified
0.981 0.019 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.981 0.019 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.981 0.019 0.000
Chapter XIV Diseases of the genitourinary system
0.981 0.019 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.978 0.022 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.976 0.024 0.000
Chapter IX Diseases of the circulatory system
0.976 0.024 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.975 0.025 0.000
N17-N19 Renal failure
0.973 0.027 0.000
I30-I52 Other forms of heart disease
0.971 0.029 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.971 0.029 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.970 0.030 0.000
M19 Other arthrosis
0.970 0.030 0.000
K70-K77 Diseases of liver
0.970 0.030 0.000
K50-K52 Noninfective enteritis and colitis
0.970 0.030 0.000
A30-A49 Other bacterial diseases
0.969 0.031 0.000
J20-J22 Other acute lower respiratory infections
0.969 0.031 0.000
N17 Acute renal failure
0.961 0.039 0.000
Chapter VII Diseases of the eye and adnexa
0.960 0.040 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.958 0.042 0.000
O60-O75 Complications of labour and delivery
0.953 0.047 0.000
M19.9 Arthrosis, unspecified
0.952 0.048 0.000
G90-G99 Other disorders of the nervous system
0.952 0.048 0.000
E10 Insulin-dependent diabetes mellitus
0.952 0.048 0.000
N17.9 Acute renal failure, unspecified
0.952 0.048 0.000
J22 Unspecified acute lower respiratory infection
0.950 0.050 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.950 0.050 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.948 0.052 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.948 0.052 0.000
N60-N64 Disorders of breast
0.941 0.059 0.000
A41 Other septicaemia
0.940 0.060 0.000
Z92 Personal history of medical treatment
0.940 0.060 0.000
K52 Other non-infective gastro-enteritis and colitis
0.938 0.062 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.936 0.064 0.000
M45-M49 Spondylopathies
0.934 0.066 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.930 0.070 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.930 0.070 0.000
K76 Other diseases of liver
0.928 0.072 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.926 0.074 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.925 0.075 0.000
D50-D53 Nutritional anaemias
0.923 0.077 0.000
K31 Other diseases of stomach and duodenum
0.922 0.078 0.000
H30-H36 Disorders of choroid and retina
0.921 0.079 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.921 0.079 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.918 0.082 0.000
I51 Complications and ill-defined descriptions of heart disease
0.912 0.088 0.000
J30-J39 Other diseases of upper respiratory tract
0.911 0.089 0.000
S60-S69 Injuries to the wrist and hand
0.911 0.089 0.000
E83 Disorders of mineral metabolism
0.910 0.090 0.000
E11 Non-insulin-dependent diabetes mellitus
0.908 0.092 0.000
Chapter XX External causes of morbidity and mortality
0.906 0.094 0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.906 0.094 0.000
T39.1 4-Aminophenol derivatives
0.906 0.094 0.000
H04 Disorders of lachrymal system
0.903 0.097 0.000
K90-K93 Other diseases of the digestive system
0.903 0.097 0.000
R13 Dysphagia
0.901 0.099 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.901 0.099 0.000
G93 Other disorders of brain
0.899 0.101 0.000
I51.8 Other ill-defined heart diseases
0.897 0.103 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.896 0.104 0.000
E87.2 Acidosis
0.896 0.104 0.000
A41.9 Septicaemia, unspecified
0.892 0.108 0.000
B25-B34 Other viral diseases
0.892 0.108 0.000
I60-I69 Cerebrovascular diseases
0.888 0.112 0.000
Chapter VIII Diseases of the ear and mastoid process
0.887 0.113 0.000
I35 Nonrheumatic aortic valve disorders
0.882 0.118 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.880 0.120 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.880 0.120 0.000
B95-B98 Bacterial, viral and other infectious agents
0.879 0.121 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.878 0.122 0.000
M47 Spondylosis
0.878 0.122 0.000
I49 Other cardiac arrhythmias
0.877 0.123 0.000
L03 Cellulitis
0.873 0.127 0.000
K31.8 Other specified diseases of stomach and duodenum
0.871 0.129 0.000
E20-E35 Disorders of other endocrine glands
0.870 0.130 0.000
K11 Diseases of salivary glands
0.867 0.133 0.000
D60-D64 Aplastic and other anaemias
0.867 0.133 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.865 0.135 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.865 0.135 0.000
J34 Other disorders of nose and nasal sinuses
0.864 0.136 0.000
Z94 Transplanted organ and tissue status
0.864 0.136 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.863 0.137 0.000
E10.3 With ophthalmic complications
0.861 0.139 0.000
R15 Faecal incontinence
0.860 0.140 0.000
J40-J47 Chronic lower respiratory diseases
0.859 0.141 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.859 0.141 0.000
D50 Iron deficiency anaemia
0.858 0.142 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.858 0.142 0.000
Chapter V Mental and behavioural disorders
0.857 0.143 0.000
E83.5 Disorders of calcium metabolism
0.853 0.147 0.000
K22 Other diseases of oesophagus
0.853 0.147 0.000
O48 Prolonged pregnancy
0.851 0.149 0.000
M19.90 Arthrosis, unspecified (Multiple sites)
0.851 0.149 0.000
K51 Ulcerative colitis
0.849 0.151 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.848 0.152 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.848 0.152 0.000
E65-E68 Obesity and other hyperalimentation
0.846 0.154 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.845 0.155 0.000
E00-E07 Disorders of thyroid gland
0.842 0.158 0.000
E87.5 Hyperkalaemia
0.841 0.159 0.000
H36 Retinal disorders in diseases classified elsewhere
0.841 0.159 0.000
G40-G47 Episodic and paroxysmal disorders
0.839 0.161 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.839 0.161 0.000
I69 Sequelae of cerebrovascular disease
0.838 0.162 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.837 0.163 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.836 0.164 0.000
I50 Heart failure
0.836 0.164 0.000
N62 Hypertrophy of breast
0.835 0.165 0.000
L08 Other local infections of skin and subcutaneous tissue
0.833 0.167 0.000
Z37 Outcome of delivery
0.831 0.169 0.000
E11.5 With peripheral circulatory complications
0.824 0.176 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.822 0.178 0.000
R04 Haemorrhage from respiratory passages
0.821 0.179 0.000
N19 Unspecified renal failure
0.821 0.179 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.818 0.182 0.000
K76.9 Liver disease, unspecified
0.818 0.182 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.818 0.182 0.000
O47 False labour
0.818 0.182 0.000
E10.9 Without complications
0.818 0.182 0.000
N63 Unspecified lump in breast
0.818 0.182 0.000
H04.2 Epiphora
0.817 0.183 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.817 0.183 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.817 0.183 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.815 0.185 0.000
G20-G26 Extrapyramidal and movement disorders
0.814 0.186 0.000
I47 Paroxysmal tachycardia
0.814 0.186 0.000
H35 Other retinal disorders
0.814 0.186 0.000
D50.8 Other iron deficiency anaemias
0.812 0.188 0.000
K70 Alcoholic liver disease
0.812 0.188 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.812 0.188 0.000
E50-E64 Other nutritional deficiencies
0.810 0.190 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.810 0.190 0.000
D52 Folate deficiency anaemia
0.809 0.191 0.000
I46 Cardiac arrest
0.807 0.193 0.000
K29 Gastritis and duodenitis
0.806 0.194 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.806 0.194 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.806 0.194 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.805 0.195 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.805 0.195 0.000
S67 Crushing injury of wrist and hand
0.804 0.196 0.000
Z86 Personal history of certain other diseases
0.803 0.197 0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.802 0.198 0.000
J90-J94 Other diseases of pleura
0.801 0.199 0.000
H34 Retinal vascular occlusions
0.801 0.199 0.000
B35-B49 Mycoses
0.799 0.200 0.000
Z36 Antenatal screening
0.799 0.201 0.000
E11.4 With neurological complications
0.798 0.202 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.796 0.204 0.000
K92 Other diseases of digestive system
0.796 0.204 0.000
G93.3 Postviral fatigue syndrome
0.796 0.204 0.000
A80-A89 Viral infections of the central nervous system
0.795 0.205 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.795 0.205 0.000
E87.6 Hypokalaemia
0.794 0.206 0.000
O36 Maternal care for other known or suspected foetal problems
0.793 0.207 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.793 0.207 0.000
K76.6 Portal hypertension
0.792 0.208 0.000
E14 Unspecified diabetes mellitus
0.792 0.208 0.000
E10.1 With ketoacidosis
0.792 0.208 0.000
S20-S29 Injuries to the thorax
0.792 0.208 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.792 0.208 0.000
Z99.3 Dependence on wheelchair
0.790 0.210 0.000
K11.2 Sialoadenitis
0.790 0.210 0.000
O63 Long labour
0.789 0.211 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.789 0.211 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.789 0.211 0.000
K05 Gingivitis and periodontal diseases
0.788 0.211 0.000
L03.2 Cellulitis of face
0.787 0.213 0.000
G70-G73 Diseases of myoneural junction and muscle
0.787 0.213 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.786 0.214 0.000
K14 Diseases of tongue
0.784 0.216 0.000
H36.0 Diabetic retinopathy
0.784 0.216 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.784 0.216 0.000
K25 Gastric ulcer
0.783 0.217 0.000
B34 Viral infection of unspecified site
0.783 0.217 0.000
Z81 Family history of mental and behavioural disorders
0.782 0.218 0.000
R00 Abnormalities of heart beat
0.782 0.218 0.000
Z93 Artificial opening status
0.781 0.219 0.000
E27 Other disorders of adrenal gland
0.780 0.219 0.000
N10-N16 Renal tubulo-interstitial diseases
0.780 0.219 0.000
G91 Hydrocephalus
0.779 0.221 0.000
J34.2 Deviated nasal septum
0.778 0.222 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.777 0.223 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.777 0.223 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.776 0.224 0.000
O70 Perineal laceration during delivery
0.775 0.225 0.000
N00-N08 Glomerular diseases
0.774 0.226 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.773 0.227 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.773 0.227 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.773 0.227 0.000
N61 Inflammatory disorders of breast
0.773 0.227 0.000
I49.9 Cardiac arrhythmia, unspecified
0.773 0.227 0.000
N18 Chronic renal failure
0.772 0.228 0.000
A49 Bacterial infection of unspecified site
0.771 0.229 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.770 0.230 0.000
I35.1 Aortic (valve) insufficiency
0.769 0.231 0.000
M18 Arthrosis of first carpometacarpal joint
0.769 0.231 0.000
M45 Ankylosing spondylitis
0.769 0.231 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.768 0.232 0.000
D64 Other anaemias
0.768 0.232 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.767 0.233 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.766 0.234 0.000
K52.1 Toxic gastro-enteritis and colitis
0.766 0.234 0.000
N64 Other disorders of breast
0.766 0.234 0.000
K09 Cysts of oral region, not elsewhere classified
0.765 0.235 0.000
K80 Cholelithiasis
0.764 0.236 0.000
Z37.0 Single live birth
0.764 0.236 0.000
Chapter II Neoplasms
0.763 0.237 0.000
M47.2 Other spondylosis with radiculopathy
0.762 0.238 0.000
H65-H75 Diseases of middle ear and mastoid
0.762 0.238 0.000
L03.1 Cellulitis of other parts of limb
0.761 0.239 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.761 0.239 0.000
Chapter XXII Codes for special purposes
0.761 0.239 0.000
Z34 Supervision of normal pregnancy
0.759 0.241 0.000
K31.5 Obstruction of duodenum
0.758 0.242 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.757 0.243 0.000
E86 Volume depletion
0.756 0.243 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.756 0.244 0.000
M47.8 Other spondylosis
0.756 0.244 0.000
M80-M85 Disorders of bone density and structure
0.755 0.245 0.000
J00-J06 Acute upper respiratory infections
0.755 0.245 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.755 0.245 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.754 0.246 0.000
K31.4 Gastric diverticulum
0.753 0.246 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.753 0.247 0.000
G93.4 Encephalopathy, unspecified
0.750 0.250 0.000
K13 Other diseases of lip and oral mucosa
0.750 0.250 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.749 0.251 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.749 0.251 0.000
R06 Abnormalities of breathing
0.749 0.251 0.000
Z89 Acquired absence of limb
0.748 0.252 0.000
K07 Dentofacial anomalies [including malocclusion]
0.747 0.253 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.747 0.253 0.000
B02 Zoster [herpes zoster]
0.747 0.253 0.000
I67 Other cerebrovascular diseases
0.746 0.254 0.000
K21 Gastro-oesophageal reflux disease
0.746 0.254 0.000
I31 Other diseases of pericardium
0.745 0.255 0.000
S50-S59 Injuries to the elbow and forearm
0.745 0.255 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.744 0.256 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.743 0.256 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.743 0.257 0.000
Z94.8 Other transplanted organ and tissue status
0.742 0.258 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.742 0.258 0.000
C15-C26 Malignant neoplasms of digestive organs
0.742 0.258 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.741 0.259 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.739 0.261 0.000
K22.7 Barrett's oesophagus
0.738 0.262 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.738 0.262 0.000
G47 Sleep disorders
0.735 0.265 0.000
E66 Obesity
0.735 0.265 0.000
K75 Other inflammatory liver diseases
0.734 0.265 0.000
J43 Emphysema
0.733 0.267 0.000
Z57 Occupational exposure to risk-factors
0.733 0.267 0.000
K92.1 Melaena
0.733 0.267 0.000
T93 Sequelae of injuries of lower limb
0.732 0.268 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.732 0.268 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.732 0.268 0.000
K51.2 Ulcerative (chronic) proctitis
0.732 0.268 0.000
I50.9 Heart failure, unspecified
0.732 0.268 0.000
I47.1 Supraventricular tachycardia
0.732 0.268 0.000
R00.1 Bradycardia, unspecified
0.732 0.268 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.731 0.269 0.000
N40-N51 Diseases of male genital organs
0.731 0.269 0.000
K31.1 Adult hypertrophic pyloric stenosis
0.730 0.270 0.000
X60-X84 Intentional self-harm
0.730 0.270 0.000
T79-T79 Certain early complications of trauma
0.729 0.270 0.000
B15-B19 Viral hepatitis
0.729 0.271 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.729 0.271 0.000
S67.0 Crushing injury of thumb and other finger(s)
0.728 0.272 0.000
Q60-Q64 Congenital malformations of the urinary system
0.728 0.272 0.000
R05 Cough
0.728 0.272 0.000
M86-M90 Other osteopathies
0.727 0.272 0.000
H55-H59 Other disorders of eye and adnexa
0.727 0.273 0.000
D52.9 Folate deficiency anaemia, unspecified
0.726 0.273 0.000
M50-M54 Other dorsopathies
0.726 0.274 0.000
T66-T78 Other and unspecified effects of external causes
0.725 0.275 0.000
Z88.6 Personal history of allergy to analgesic agent
0.724 0.276 0.000
R01 Cardiac murmurs and other cardiac sounds
0.722 0.278 0.000
O80-O84 Delivery
0.722 0.278 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.722 0.278 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.721 0.279 0.000
R04.0 Epistaxis
0.721 0.279 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.720 0.280 0.000
R14 Flatulence and related conditions
0.720 0.280 0.000
L50-L54 Urticaria and erythema
0.719 0.281 0.000
I33 Acute and subacute endocarditis
0.718 0.282 0.000
G30-G32 Other degenerative diseases of the nervous system
0.717 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E40-E46 Malnutrition
0.717 0.283 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.716 0.284 0.000
D69 Purpura and other haemorrhagic conditions
0.716 0.284 0.000
B25 Cytomegaloviral disease
0.716 0.284 0.000
T33-T35 Frostbite
0.715 0.284 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.715 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.715 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.715 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.715 0.284 0.000
S10-S19 Injuries to the neck
0.715 0.284 0.000
B99-B99 Other infectious diseases
0.715 0.285 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.715 0.285 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.715 0.285 0.000
B65-B83 Helminthiases
0.715 0.285 0.000
B50-B64 Protozoal diseases
0.715 0.285 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.715 0.285 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.715 0.285 0.000
A75-A79 Rickettsioses
0.715 0.285 0.000
A70-A74 Other diseases caused by chlamydiae
0.715 0.285 0.000
A65-A69 Other spirochaetal diseases
0.715 0.285 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.715 0.285 0.000
A20-A28 Certain zoonotic bacterial diseases
0.715 0.285 0.000
A15-A19 Tuberculosis
0.715 0.285 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.715 0.285 0.000
M91-M94 Chondropathies
0.715 0.285 0.000
M60-M63 Disorders of muscles
0.715 0.285 0.000
M00-M03 Infectious arthropathies
0.715 0.285 0.000
K12 Stomatitis and related lesions
0.715 0.285 0.000
H90-H95 Other disorders of ear
0.714 0.285 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.714 0.286 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.713 0.287 0.000
E88 Other metabolic disorders
0.713 0.287 0.000
E85 Amyloidosis
0.713 0.287 0.000
E84 Cystic fibrosis
0.713 0.287 0.000
E79 Disorders of purine and pyrimidine metabolism
0.713 0.287 0.000
E77 Disorders of glycoprotein metabolism
0.713 0.287 0.000
E76 Disorders of glycosaminoglycan metabolism
0.713 0.287 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.713 0.287 0.000
E74 Other disorders of carbohydrate metabolism
0.713 0.287 0.000
E73 Lactose intolerance
0.713 0.287 0.000
E72 Other disorders of amino-acid metabolism
0.713 0.287 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.713 0.287 0.000
E70 Disorders of aromatic amino-acid metabolism
0.713 0.287 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.713 0.287 0.000
M15 Polyarthrosis
0.713 0.287 0.000
I35.0 Aortic (valve) stenosis
0.713 0.287 0.000
O85-O92 Complications predominantly related to the puerperium
0.713 0.287 0.000
J34.1 Cyst and mucocele of nose and nasal sinus
0.712 0.288 0.000
T92 Sequelae of injuries of upper limb
0.711 0.289 0.000
Z35 Supervision of high-risk pregnancy
0.711 0.289 0.000
Z88.2 Personal history of allergy to sulphonamides
0.711 0.289 0.000
K29.6 Other gastritis
0.710 0.290 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.710 0.290 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.710 0.290 0.000
O62 Abnormalities of forces of labour
0.709 0.291 0.000
E13 Other specified diabetes mellitus
0.709 0.291 0.000
E12 Malnutrition-related diabetes mellitus
0.709 0.291 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.708 0.292 0.000
O63.1 Prolonged second stage (of labour)
0.708 0.292 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.707 0.293 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.706 0.294 0.000
M16.7 Other secondary coxarthrosis
0.705 0.294 0.000
M16.6 Other secondary coxarthrosis, bilateral
0.705 0.294 0.000
M16.5 Other posttraumatic coxarthrosis
0.705 0.294 0.000
M16.4 Posttraumatic coxarthrosis, bilateral
0.705 0.294 0.000
M16.3 Other dysplastic coxarthrosis
0.705 0.294 0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral
0.705 0.294 0.000
S00-S09 Injuries to the head
0.705 0.295 0.000
B34.9 Viral infection, unspecified
0.705 0.295 0.000
D50.9 Iron deficiency anaemia, unspecified
0.704 0.296 0.000
Z86.0 Personal history of other neoplasms
0.704 0.296 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.703 0.296 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.703 0.297 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.703 0.297 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.703 0.297 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.703 0.297 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.703 0.297 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.703 0.297 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.703 0.297 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.703 0.297 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.703 0.297 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.703 0.297 0.000
T36 Poisoning by systemic antibiotics
0.703 0.297 0.000
M47.9 Spondylosis, unspecified
0.703 0.297 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.702 0.298 0.000
M70-M79 Other soft tissue disorders
0.702 0.298 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.702 0.298 0.000
Z94.0 Kidney transplant status
0.702 0.298 0.000
A41.8 Other specified septicaemia
0.701 0.298 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.701 0.299 0.000
D55-D59 Haemolytic anaemias
0.701 0.299 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.701 0.299 0.000
Z97 Presence of other devices
0.701 0.299 0.000
E87.0 Hyperosmolality and hypernatraemia
0.700 0.300 0.000
H10-H13 Disorders of conjunctiva
0.700 0.300 0.000
O30 Multiple gestation
0.700 0.300 0.000
Z84 Family history of other conditions
0.700 0.300 0.000
I00-I02 Acute rheumatic fever
0.700 0.300 0.000
I50.0 Congestive heart failure
0.700 0.300 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.699 0.301 0.000
G93.0 Cerebral cysts
0.699 0.301 0.000
O45 Premature separation of placenta [abruptio placentae]
0.699 0.301 0.000
O44 Placenta praevia
0.699 0.301 0.000
O43 Placental disorders
0.699 0.301 0.000
O41 Other disorders of amniotic fluid and membranes
0.699 0.301 0.000
O33 Maternal care for known or suspected disproportion
0.699 0.301 0.000
O31 Complications specific to multiple gestation
0.699 0.301 0.000
O40 Polyhydramnios
0.699 0.301 0.000
J92 Pleural plaque
0.699 0.301 0.000
H35.6 Retinal haemorrhage
0.699 0.301 0.000
S61 Open wound of wrist and hand
0.698 0.302 0.000
I42 Cardiomyopathy
0.698 0.302 0.000
J60-J70 Lung diseases due to external agents
0.698 0.302 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.698 0.302 0.000
D64.9 Anaemia, unspecified
0.698 0.302 0.000
K90 Intestinal malabsorption
0.697 0.303 0.000
N99-N99 Other disorders of the genitourinary system
0.697 0.303 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.697 0.303 0.000
M19.0 Primary arthrosis of other joints
0.697 0.303 0.000
K83 Other diseases of biliary tract
0.697 0.303 0.000
I52 Other heart disorders in diseases classified elsewhere
0.696 0.304 0.000
I48 Atrial fibrillation and flutter
0.696 0.304 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.696 0.304 0.000
I41 Myocarditis in diseases classified elsewhere
0.696 0.304 0.000
I40 Acute myocarditis
0.696 0.304 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.696 0.304 0.000
I37 Pulmonary valve disorders
0.696 0.304 0.000
I36 Nonrheumatic tricuspid valve disorders
0.696 0.304 0.000
I32 Pericarditis in diseases classified elsewhere
0.696 0.304 0.000
I30 Acute pericarditis
0.696 0.304 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.696 0.304 0.000
E87.4 Mixed disorder of acid-base balance
0.696 0.304 0.000
E87.3 Alkalosis
0.696 0.304 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.696 0.304 0.000
K28 Gastrojejunal ulcer
0.696 0.304 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.696 0.304 0.000
M19.8 Other specified arthrosis
0.695 0.304 0.000
M19.2 Other secondary arthrosis
0.695 0.304 0.000
M19.1 Posttraumatic arthrosis of other joints
0.695 0.304 0.000
R17 Unspecified jaundice
0.695 0.304 0.000
K22.9 Disease of oesophagus, unspecified
0.695 0.305 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.695 0.305 0.000
K77 Liver disorders in diseases classified elsewhere
0.695 0.305 0.000
K73 Chronic hepatitis, not elsewhere classified
0.695 0.305 0.000
K72 Hepatic failure, not elsewhere classified
0.695 0.305 0.000
K71 Toxic liver disease
0.695 0.305 0.000
A48 Other bacterial diseases, not elsewhere classified
0.695 0.305 0.000
A44 Bartonellosis
0.695 0.305 0.000
A43 Nocardiosis
0.695 0.305 0.000
A42 Actinomycosis
0.695 0.305 0.000
A40 Streptococcal septicaemia
0.695 0.305 0.000
A39 Meningococcal infection
0.695 0.305 0.000
A37 Whooping cough
0.695 0.305 0.000
A36 Diphtheria
0.695 0.305 0.000
A32 Listeriosis
0.695 0.305 0.000
A31 Infection due to other mycobacteria
0.695 0.305 0.000
A30 Leprosy [Hansen's disease]
0.695 0.305 0.000
A46 Erysipelas
0.695 0.305 0.000
A38 Scarlet fever
0.695 0.305 0.000
A35 Other tetanus
0.695 0.305 0.000
A34 Obstetrical tetanus
0.695 0.305 0.000
A33 Tetanus neonatorum
0.695 0.305 0.000
J21 Acute bronchiolitis
0.694 0.305 0.000
J20 Acute bronchitis
0.694 0.305 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.694 0.306 0.000
E11.3 With ophthalmic complications
0.693 0.307 0.000
Z60 Problems related to social environment
0.692 0.308 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.692 0.308 0.000
K27 Peptic ulcer, site unspecified
0.692 0.308 0.000
Z99.2 Dependence on renal dialysis
0.692 0.308 0.000
M19.98 Arthrosis, unspecified (Other)
0.690 0.310 0.000
O00-O08 Pregnancy with abortive outcome
0.690 0.310 0.000
H00 Hordeolum and chalazion
0.690 0.310 0.000
L60-L75 Disorders of skin appendages
0.689 0.311 0.000
J44 Other chronic obstructive pulmonary disease
0.689 0.311 0.000
Z63 Other problems related to primary support group, including family circumstances
0.689 0.311 0.000
V10-V19 Pedal cyclist injured in transport accident
0.689 0.311 0.000
N17.8 Other acute renal failure
0.689 0.311 0.000
N17.2 Acute renal failure with medullary necrosis
0.689 0.311 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.689 0.311 0.000
N17.0 Acute renal failure with tubular necrosis
0.689 0.311 0.000
H34.8 Other retinal vascular occlusions
0.688 0.312 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.688 0.312 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.688 0.312 0.000
I38 Endocarditis, valve unspecified
0.688 0.312 0.000
E78.5 Hyperlipidaemia, unspecified
0.688 0.312 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.687 0.313 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.687 0.313 0.000
L10-L14 Bullous disorders
0.687 0.313 0.000
J34.3 Hypertrophy of nasal turbinates
0.687 0.313 0.000
I49.5 Sick sinus syndrome
0.687 0.313 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.686 0.314 0.000
K08 Other disorders of teeth and supporting structures
0.685 0.315 0.000
S90-S99 Injuries to the ankle and foot
0.685 0.315 0.000
S69 Other and unspecified injuries of wrist and hand
0.684 0.315 0.000
Z39 Postpartum care and examination
0.684 0.315 0.000
K11.5 Sialolithiasis
0.684 0.316 0.000
O74 Complications of anaesthesia during labour and delivery
0.683 0.317 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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