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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs72727394
log Bayes Factor = 12.5933
Chromosome 15   position 38,847,022  (GRCh37) Explore rs72727394 on Ensembl!
Variant rs72727394 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.997 0.003 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.994 0.006 0.000
M65-M68 Disorders of synovium and tendon
0.993 0.007 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.992 0.008 0.000
M65 Synovitis and tenosynovitis
0.991 0.009 0.000
M86-M90 Other osteopathies
0.988 0.012 0.000
E50-E64 Other nutritional deficiencies
0.987 0.013 0.000
E20-E35 Disorders of other endocrine glands
0.984 0.016 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.984 0.016 0.000
M05-M14 Inflammatory polyarthropathies
0.979 0.021 0.000
M40-M43 Deforming dorsopathies
0.972 0.028 0.000
E11 Non-insulin-dependent diabetes mellitus
0.964 0.036 0.000
M43 Other deforming dorsopathies
0.961 0.039 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.960 0.040 0.000
E53 Deficiency of other B group vitamins
0.956 0.044 0.000
E29 Testicular dysfunction
0.954 0.046 0.000
E05.9 Thyrotoxicosis, unspecified
0.946 0.054 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.943 0.057 0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.941 0.059 0.000
E53.8 Deficiency of other specified B group vitamins
0.941 0.059 0.000
M43.1 Spondylolisthesis
0.941 0.059 0.000
# Top node
0.937 0.063 0.000
E29.1 Testicular hypofunction
0.932 0.068 0.000
E61 Deficiency of other nutrient elements
0.931 0.069 0.000
M43.17 Spondylolisthesis (Lumbosacral region)
0.930 0.070 0.000
M07 Psoriatic and enteropathic arthropathies
0.926 0.074 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.921 0.079 0.000
E27 Other disorders of adrenal gland
0.920 0.080 0.000
M89 Other disorders of bone
0.920 0.080 0.000
Chapter VIII Diseases of the ear and mastoid process
0.920 0.080 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.918 0.082 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.912 0.088 0.000
E11.1 With ketoacidosis
0.910 0.090 0.000
M87 Osteonecrosis
0.910 0.090 0.000
E10 Insulin-dependent diabetes mellitus
0.904 0.096 0.000
L03 Cellulitis
0.903 0.097 0.000
E11.9 Without complications
0.901 0.099 0.000
E14 Unspecified diabetes mellitus
0.900 0.100 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.895 0.105 0.000
M06 Other rheumatoid arthritis
0.894 0.106 0.000
M80-M85 Disorders of bone density and structure
0.894 0.106 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.889 0.111 0.000
M07.3 Other psoriatic arthropathies
0.889 0.111 0.000
E61.1 Iron deficiency
0.887 0.113 0.000
L03.9 Cellulitis, unspecified
0.887 0.113 0.000
M86 Osteomyelitis
0.884 0.116 0.000
H65-H75 Diseases of middle ear and mastoid
0.879 0.121 0.000
L03.1 Cellulitis of other parts of limb
0.869 0.131 0.000
M89.8 Other specified disorders of bone
0.868 0.132 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.865 0.135 0.000
E10.9 Without complications
0.862 0.138 0.000
M45-M49 Spondylopathies
0.861 0.139 0.000
H90-H95 Other disorders of ear
0.861 0.139 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.860 0.140 0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified
0.858 0.142 0.000
M20-M25 Other joint disorders
0.856 0.144 0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.853 0.147 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.852 0.148 0.000
H92 Otalgia and effusion of ear
0.849 0.151 0.000
E14.3 With ophthalmic complications
0.844 0.156 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.840 0.160 0.000
M48 Other spondylopathies
0.839 0.161 0.000
M84 Disorders of continuity of bone
0.836 0.164 0.000
H92.0 Otalgia
0.829 0.171 0.000
M06.9 Rheumatoid arthritis, unspecified
0.827 0.173 0.000
M13 Other arthritis
0.824 0.176 0.000
E22 Hyperfunction of pituitary gland
0.822 0.178 0.000
M22 Disorders of patella
0.819 0.181 0.000
E11.3 With ophthalmic complications
0.817 0.183 0.000
M87.9 Osteonecrosis, unspecified
0.814 0.186 0.000
E13 Other specified diabetes mellitus
0.814 0.186 0.000
E10.0 With coma
0.813 0.187 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.812 0.188 0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)
0.811 0.189 0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.809 0.191 0.000
M31 Other necrotising vasculopathies
0.805 0.195 0.000
M43.0 Spondylolysis
0.800 0.200 0.000
M06.4 Inflammatory polyarthropathy
0.797 0.203 0.000
H74 Other disorders of middle ear and mastoid
0.795 0.205 0.000
E06 Thyroiditis
0.795 0.205 0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.793 0.207 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.791 0.209 0.000
E21.3 Hyperparathyroidism, unspecified
0.788 0.212 0.000
L40-L45 Papulosquamous disorders
0.788 0.212 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.784 0.216 0.000
M12 Other specific arthropathies
0.784 0.216 0.000
H71 Cholesteatoma of middle ear
0.781 0.219 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.780 0.220 0.000
E05.8 Other thyrotoxicosis
0.779 0.221 0.000
E11.4 With neurological complications
0.774 0.226 0.000
E27.1 Primary adrenocortical insufficiency
0.774 0.226 0.000
E03.8 Other specified hypothyroidism
0.772 0.228 0.000
M43.2 Other fusion of spine
0.772 0.228 0.000
Chapter XXII Codes for special purposes
0.772 0.228 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.771 0.229 0.000
M60-M63 Disorders of muscles
0.768 0.232 0.000
M15-M19 Arthrosis
0.767 0.233 0.000
M00-M03 Infectious arthropathies
0.766 0.234 0.000
M84.0 Malunion of fracture
0.765 0.235 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.761 0.239 0.000
M86.6 Other chronic osteomyelitis
0.759 0.241 0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)
0.757 0.243 0.000
M89.83 Other specified disorders of bone (Forearm)
0.754 0.246 0.000
M84.03 Malunion of fracture (Forearm)
0.752 0.248 0.000
H73 Other disorders of tympanic membrane
0.748 0.252 0.000
D80-D89 Certain disorders involving the immune mechanism
0.748 0.252 0.000
L40 Psoriasis
0.748 0.252 0.000
M48.0 Spinal stenosis
0.747 0.253 0.000
H92.1 Otorrhoea
0.747 0.253 0.000
M05 Seropositive rheumatoid arthritis
0.745 0.255 0.000
M89.4 Other hypertrophic osteo-arthropathy
0.742 0.258 0.000
E70-E90 Metabolic disorders
0.741 0.259 0.000
E85 Amyloidosis
0.740 0.260 0.000
E11.8 With unspecified complications
0.740 0.260 0.000
M31.3 Wegener's granulomatosis
0.738 0.262 0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)
0.737 0.263 0.000
E14.6 With other specified complications
0.735 0.265 0.000
M18 Arthrosis of first carpometacarpal joint
0.734 0.266 0.000
M43.19 Spondylolisthesis (Site unspecified)
0.732 0.268 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.731 0.269 0.000
D86 Sarcoidosis
0.731 0.269 0.000
L10-L14 Bullous disorders
0.731 0.269 0.000
M13.0 Polyarthritis, unspecified
0.729 0.271 0.000
E03.1 Congenital hypothyroidism without goitre
0.727 0.272 0.000
L40.5 Arthropathic psoriasis
0.724 0.276 0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.724 0.276 0.000
E58 Dietary calcium deficiency
0.722 0.278 0.000
M24 Other specific joint derangements
0.721 0.279 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
M22.4 Chondromalacia patellae
0.717 0.283 0.000
M87.8 Other osteonecrosis
0.716 0.284 0.000
M43.6 Torticollis
0.715 0.285 0.000
E12 Malnutrition-related diabetes mellitus
0.715 0.285 0.000
M89.81 Other specified disorders of bone (Shoulder region)
0.714 0.286 0.000
E05.5 Thyroid crisis or storm
0.712 0.288 0.000
E05.4 Thyrotoxicosis factitia
0.712 0.288 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.712 0.288 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.712 0.288 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.712 0.288 0.000
M31.1 Thrombotic microangiopathy
0.712 0.288 0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)
0.711 0.289 0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)
0.711 0.289 0.000
M30 Polyarteritis nodosa and related conditions
0.711 0.289 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.711 0.289 0.000
M65.2 Calcific tendinitis
0.711 0.289 0.000
M65.0 Abscess of tendon sheath
0.711 0.289 0.000
H70 Mastoiditis and related conditions
0.710 0.290 0.000
M87.2 Osteonecrosis due to previous trauma
0.710 0.290 0.000
E51 Thiamine deficiency
0.709 0.291 0.000
Chapter XX External causes of morbidity and mortality
0.709 0.291 0.000
M43.02 Spondylolysis (Cervical region)
0.708 0.292 0.000
M34 Systemic sclerosis
0.708 0.292 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.707 0.293 0.000
E63 Other nutritional deficiencies
0.707 0.293 0.000
E56 Other vitamin deficiencies
0.707 0.293 0.000
E50 Vitamin A deficiency
0.707 0.293 0.000
E60 Dietary zinc deficiency
0.707 0.293 0.000
E59 Dietary selenium deficiency
0.707 0.293 0.000
E54 Ascorbic acid deficiency
0.707 0.293 0.000
E52 Niacin deficiency [pellagra]
0.707 0.293 0.000
M88 Paget's disease of bone [osteitis deformans]
0.706 0.294 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.706 0.294 0.000
E32 Diseases of thymus
0.706 0.294 0.000
E31 Polyglandular dysfunction
0.706 0.294 0.000
E30 Disorders of puberty, not elsewhere classified
0.706 0.294 0.000
E25 Adrenogenital disorders
0.706 0.294 0.000
E20 Hypoparathyroidism
0.705 0.295 0.000
M22.2 Patellofemoral disorders
0.703 0.297 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.703 0.297 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.702 0.298 0.000
M08 Juvenile arthritis
0.702 0.298 0.000
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.701 0.299 0.000
E13.3 With ophthalmic complications
0.701 0.299 0.000
E21.4 Other specified disorders of parathyroid gland
0.700 0.300 0.000
Q00-Q07 Congenital malformations of the nervous system
0.700 0.300 0.000
M89.89 Other specified disorders of bone (Site unspecified)
0.698 0.302 0.000
E28 Ovarian dysfunction
0.698 0.302 0.000
M42 Spinal osteochondrosis
0.697 0.303 0.000
E61.2 Magnesium deficiency
0.696 0.304 0.000
E65-E68 Obesity and other hyperalimentation
0.696 0.304 0.000
M65.1 Other infective (teno)synovitis
0.696 0.304 0.000
E85.3 Secondary systemic amyloidosis
0.696 0.304 0.000
M86.8 Other osteomyelitis
0.695 0.305 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.694 0.306 0.000
Y85 Sequelae of transport accidents
0.693 0.307 0.000
E10.5 With peripheral circulatory complications
0.693 0.307 0.000
E11.7 With multiple complications
0.691 0.309 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.690 0.310 0.000
E85.4 Organ-limited amyloidosis
0.690 0.310 0.000
L08 Other local infections of skin and subcutaneous tissue
0.690 0.310 0.000
M43.9 Deforming dorsopathy, unspecified
0.689 0.311 0.000
M43.8 Other specified deforming dorsopathies
0.689 0.311 0.000
M43.5 Other recurrent vertebral subluxation
0.689 0.311 0.000
M43.4 Other recurrent atlantoaxial subluxation
0.689 0.311 0.000
M43.3 Recurrent atlantoaxial subluxation with myelopathy
0.689 0.311 0.000
E14.4 With neurological complications
0.689 0.311 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.688 0.312 0.000
E85.9 Amyloidosis, unspecified
0.687 0.313 0.000
M86.9 Osteomyelitis, unspecified
0.687 0.313 0.000
E53.1 Pyridoxine deficiency
0.686 0.314 0.000
E53.0 Riboflavin deficiency
0.686 0.314 0.000
H74.0 Tympanosclerosis
0.685 0.315 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.685 0.315 0.000
E29.9 Testicular dysfunction, unspecified
0.684 0.316 0.000
E29.8 Other testicular dysfunction
0.684 0.316 0.000
E29.0 Testicular hyperfunction
0.684 0.316 0.000
H73.8 Other specified disorders of tympanic membrane
0.683 0.317 0.000
M48.02 Spinal stenosis (Cervical region)
0.683 0.317 0.000
M89.3 Hypertrophy of bone
0.683 0.317 0.000
E27.8 Other specified disorders of adrenal gland
0.679 0.321 0.000
M43.12 Spondylolisthesis (Cervical region)
0.676 0.324 0.000
H65 Nonsuppurative otitis media
0.676 0.324 0.000
M87.91 Osteonecrosis, unspecified (Shoulder region)
0.675 0.325 0.000
M81 Osteoporosis without pathological fracture
0.675 0.325 0.000
E14.5 With peripheral circulatory complications
0.675 0.325 0.000
L03.2 Cellulitis of face
0.675 0.325 0.000
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)
0.674 0.326 0.000
M43.15 Spondylolisthesis (Thoracolumbar region)
0.674 0.326 0.000
M43.14 Spondylolisthesis (Thoracic region)
0.674 0.326 0.000
M43.13 Spondylolisthesis (Cervicothoracic region)
0.674 0.326 0.000
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)
0.674 0.326 0.000
M43.10 Spondylolisthesis (Multiple sites in spine)
0.674 0.326 0.000
M85 Other disorders of bone density and structure
0.673 0.327 0.000
M24.2 Disorder of ligament
0.673 0.327 0.000
M49 Spondylopathies in diseases classified elsewhere
0.672 0.328 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.672 0.328 0.000
Q25 Congenital malformations of great arteries
0.669 0.331 0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)
0.669 0.331 0.000
E10.8 With unspecified complications
0.668 0.332 0.000
E61.9 Deficiency of nutrient element, unspecified
0.668 0.332 0.000
E61.8 Deficiency of other specified nutrient elements
0.668 0.332 0.000
E61.7 Deficiency of multiple nutrient elements
0.668 0.332 0.000
E61.6 Vanadium deficiency
0.668 0.332 0.000
E61.5 Molybdenum deficiency
0.668 0.332 0.000
E61.4 Chromium deficiency
0.668 0.332 0.000
E61.3 Manganese deficiency
0.668 0.332 0.000
E61.0 Copper deficiency
0.668 0.332 0.000
M31.7 Microscopic polyangiitis
0.666 0.334 0.000
M89.84 Other specified disorders of bone (Hand)
0.665 0.335 0.000
M07.6 Other enteropathic arthropathies
0.664 0.336 0.000
M07.5 Arthropathy in ulcerative colitis
0.664 0.336 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.664 0.336 0.000
M07.2 Psoriatic spondylitis
0.664 0.336 0.000
M07.1 Arthritis mutilans
0.664 0.336 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.664 0.336 0.000
M99 Biomechanical lesions, not elsewhere classified
0.664 0.336 0.000
M90 Osteopathies in diseases classified elsewhere
0.664 0.336 0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)
0.663 0.337 0.000
M89.0 Algoneurodystrophy
0.662 0.338 0.000
H74.8 Other specified disorders of middle ear and mastoid
0.661 0.339 0.000
M83 Adult osteomalacia
0.660 0.340 0.000
E27.5 Adrenomedullary hyperfunction
0.659 0.340 0.000
E27.0 Other adrenocortical overactivity
0.659 0.340 0.000
M89.6 Osteopathy after poliomyelitis
0.659 0.340 0.000
M89.2 Other disorders of bone development and growth
0.659 0.340 0.000
M89.1 Epiphyseal arrest
0.659 0.340 0.000
E14.8 With unspecified complications
0.658 0.342 0.000
L00 Staphylococcal scalded skin syndrome
0.658 0.342 0.000
M89.5 Osteolysis
0.657 0.343 0.000
L60-L75 Disorders of skin appendages
0.657 0.343 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.657 0.343 0.000
H74.4 Polyp of middle ear
0.656 0.344 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.656 0.344 0.000
H80-H83 Diseases of inner ear
0.655 0.345 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.655 0.345 0.000
Y85.9 Sequelae of other and unspecified transport accidents
0.654 0.346 0.000
L01 Impetigo
0.654 0.346 0.000
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate
0.654 0.346 0.000
M96.9 Postprocedural musculoskeletal disorder, unspecified
0.654 0.346 0.000
M96.5 Postradiation scoliosis
0.654 0.346 0.000
M96.4 Postsurgical lordosis
0.654 0.346 0.000
M96.3 Postlaminectomy kyphosis
0.654 0.346 0.000
M96.2 Postradiation kyphosis
0.654 0.346 0.000
M40 Kyphosis and lordosis
0.653 0.347 0.000
M87.3 Other secondary osteonecrosis
0.652 0.347 0.000
M87.1 Osteonecrosis due to drugs
0.652 0.347 0.000
M87.0 Idiopathic aseptic necrosis of bone
0.652 0.347 0.000
Y85.0 Sequelae of motor-vehicle accident
0.652 0.348 0.000
M84.3 Stress fracture, not elsewhere classified
0.651 0.348 0.000
M12.3 Palindromic rheumatism
0.651 0.349 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.650 0.350 0.000
D86.1 Sarcoidosis of lymph nodes
0.650 0.350 0.000
M11 Other crystal arthropathies
0.650 0.350 0.000
E34 Other endocrine disorders
0.649 0.351 0.000
E10.7 With multiple complications
0.648 0.352 0.000
D86.0 Sarcoidosis of lung
0.648 0.352 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.648 0.352 0.000
M66 Spontaneous rupture of synovium and tendon
0.647 0.352 0.000
Q23 Congenital malformations of aortic and mitral valves
0.646 0.354 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.646 0.354 0.000
E11.0 With coma
0.646 0.354 0.000
E14.7 With multiple complications
0.645 0.355 0.000
E14.2 Withrenal complications
0.645 0.355 0.000
E14.0 With coma
0.645 0.355 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.645 0.355 0.000
M48.9 Spondylopathy, unspecified
0.644 0.356 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.643 0.357 0.000
M15 Polyarthrosis
0.641 0.359 0.000
M06.8 Other specified rheumatoid arthritis
0.641 0.359 0.000
M06.2 Rheumatoid bursitis
0.641 0.359 0.000
M06.1 Adult-onset Still's disease
0.641 0.359 0.000
M87.98 Osteonecrosis, unspecified (Other)
0.640 0.359 0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.639 0.361 0.000
M14 Arthropathies in other diseases classified elsewhere
0.638 0.361 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.638 0.362 0.000
M07.38 Other psoriatic arthropathies (Other)
0.637 0.363 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.637 0.363 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.637 0.363 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.637 0.363 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.637 0.363 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.637 0.363 0.000
E21.2 Other hyperparathyroidism
0.637 0.363 0.000
D50-D53 Nutritional anaemias
0.637 0.363 0.000
M43.27 Other fusion of spine (Lumbosacral region)
0.636 0.364 0.000
M02 Reactive arthropathies
0.636 0.364 0.000
E27.9 Disorder of adrenal gland, unspecified
0.635 0.365 0.000
M86.5 Other chronic haematogenous osteomyelitis
0.634 0.366 0.000
M86.4 Chronic osteomyelitis with draining sinus
0.634 0.366 0.000
M86.3 Chronic multifocal osteomyelitis
0.634 0.366 0.000
M86.2 Subacute osteomyelitis
0.634 0.366 0.000
M86.1 Other acute osteomyelitis
0.634 0.366 0.000
M86.0 Acute haematogenous osteomyelitis
0.634 0.366 0.000
E06.9 Thyroiditis, unspecified
0.634 0.366 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.634 0.366 0.000
M87.96 Osteonecrosis, unspecified (Lower leg)
0.633 0.367 0.000
Q24 Other congenital malformations of heart
0.633 0.367 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.631 0.368 0.000
E26 Hyperaldosteronism
0.631 0.369 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.630 0.370 0.000
H68 Eustachian salpingitis and obstruction
0.630 0.370 0.000
H67 Otitis media in diseases classified elsewhere
0.630 0.370 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.630 0.370 0.000
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)
0.630 0.370 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.630 0.370 0.000
D84 Other immunodeficiencies
0.628 0.372 0.000
M22.0 Recurrent dislocation of patella
0.627 0.372 0.000
M22.8 Other disorders of patella
0.627 0.373 0.000
M48.8 Other specified spondylopathies
0.627 0.373 0.000
E04 Other non-toxic goitre
0.627 0.373 0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.625 0.374 0.000
E11.6 With other specified complications
0.624 0.375 0.000
E27.2 Addisonian crisis
0.624 0.376 0.000
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)
0.624 0.376 0.000
L08.8 Other specified local infections of skin and subcutaneous tissue
0.624 0.376 0.000
M89.82 Other specified disorders of bone (Upper arm)
0.622 0.378 0.000
M89.80 Other specified disorders of bone (Multiple sites)
0.622 0.378 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.622 0.378 0.000
D51 Vitamin B12 deficiency anaemia
0.621 0.379 0.000
Q05 Spina bifida
0.621 0.379 0.000
M13.9 Arthritis, unspecified
0.620 0.380 0.000
M89.88 Other specified disorders of bone (Other)
0.620 0.380 0.000
Y86 Sequelae of other accidents
0.619 0.381 0.000
E65 Localised adiposity
0.619 0.381 0.000
M22.9 Disorder of patella, unspecified
0.619 0.381 0.000
D60-D64 Aplastic and other anaemias
0.618 0.382 0.000
W50-W64 Exposure to animate mechanical forces
0.617 0.383 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.617 0.383 0.000
E14.1 With ketoacidosis
0.617 0.383 0.000
M22.3 Other derangements of patella
0.617 0.383 0.000
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)
0.614 0.386 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.613 0.387 0.000
L40.4 Guttate psoriasis
0.612 0.388 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.611 0.389 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.610 0.390 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.610 0.390 0.000
M62 Other disorders of muscle
0.610 0.390 0.000
H92.2 Otorrhagia
0.609 0.391 0.000
M84.4 Pathological fracture, not elsewhere classified
0.608 0.392 0.000
M89.86 Other specified disorders of bone (Lower leg)
0.608 0.392 0.000
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites
0.607 0.393 0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)
0.607 0.393 0.000
M91-M94 Chondropathies
0.606 0.393 0.000
V40-V49 Car occupant injured in transport accident
0.604 0.396 0.000
E10.6 With other specified complications
0.604 0.396 0.000
M48.4 Fatigue fracture of vertebra
0.602 0.398 0.000
M48.3 Traumatic spondylopathy
0.602 0.398 0.000
M48.2 Kissing spine
0.602 0.398 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.602 0.398 0.000
M13.04 Polyarthritis, unspecified (Hand)
0.601 0.399 0.000
E10.3 With ophthalmic complications
0.601 0.399 0.000
D86.8 Sarcoidosis of other and combined sites
0.600 0.400 0.000
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)
0.600 0.400 0.000
M86.67 Other chronic osteomyelitis (Ankle and foot)
0.600 0.400 0.000
M86.66 Other chronic osteomyelitis (Lower leg)
0.600 0.400 0.000
M84.9 Disorder of continuity of bone, unspecified
0.599 0.401 0.000
M84.2 Delayed union of fracture
0.599 0.401 0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)
0.599 0.401 0.000
M86.69 Other chronic osteomyelitis (Site unspecified)
0.597 0.403 0.000
E28.3 Primary ovarian failure
0.597 0.403 0.000
D61 Other aplastic anaemias
0.597 0.403 0.000
U88 Agent resistant to multiple antibiotics
0.596 0.404 0.000
M84.8 Other disorders of continuity of bone
0.596 0.404 0.000
M48.09 Spinal stenosis (Site unspecified)
0.596 0.404 0.000
M34.1 CR(E)ST syndrome
0.593 0.407 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.593 0.407 0.000
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)
0.592 0.407 0.000
L73 Other follicular disorders
0.592 0.408 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.592 0.408 0.000
L11 Other acantholytic disorders
0.591 0.408 0.000
M06.3 Rheumatoid nodule
0.591 0.409 0.000
M13.1 Monoarthritis, not elsewhere classified
0.591 0.409 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.589 0.411 0.000
E22.8 Other hyperfunction of pituitary gland
0.589 0.411 0.000
E06.3 Autoimmune thyroiditis
0.589 0.411 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.588 0.411 0.000
E53.9 Vitamin B deficiency, unspecified
0.588 0.412 0.000
L04 Acute lymphadenitis
0.588 0.412 0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint
0.588 0.412 0.000
M22.1 Recurrent subluxation of patella
0.587 0.413 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.587 0.413 0.000
L03.3 Cellulitis of trunk
0.584 0.416 0.000
M87.99 Osteonecrosis, unspecified (Site unspecified)
0.584 0.416 0.000
M87.94 Osteonecrosis, unspecified (Hand)
0.584 0.416 0.000
M87.93 Osteonecrosis, unspecified (Forearm)
0.584 0.416 0.000
M87.92 Osteonecrosis, unspecified (Upper arm)
0.584 0.416 0.000
M87.90 Osteonecrosis, unspecified (Multiple sites)
0.584 0.416 0.000
E13.8 With unspecified complications
0.584 0.416 0.000
E13.7 With multiple complications
0.584 0.416 0.000
E13.6 With other specified complications
0.584 0.416 0.000
E13.5 With peripheral circulatory complications
0.584 0.416 0.000
E13.4 With neurological complications
0.584 0.416 0.000
E13.2 With renal complications
0.584 0.416 0.000
E13.1 With ketoacidosis
0.584 0.416 0.000
E13.0 With coma
0.584 0.416 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.583 0.417 0.000
Q35-Q37 Cleft lip and cleft palate
0.582 0.417 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.582 0.417 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.582 0.418 0.000
D61.9 Aplastic anaemia, unspecified
0.582 0.418 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.581 0.419 0.000
M13.00 Polyarthritis, unspecified (Multiple sites)
0.580 0.419 0.000
E84 Cystic fibrosis
0.580 0.420 0.000
M43.09 Spondylolysis (Site unspecified)
0.578 0.421 0.000
M33 Dermatopolymyositis
0.578 0.422 0.000
M31.9 Necrotising vasculopathy, unspecified
0.577 0.422 0.000
M31.8 Other specified necrotising vasculopathies
0.577 0.422 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.577 0.422 0.000
M31.2 Lethal midline granuloma
0.577 0.422 0.000
M31.0 Hypersensitivity angiitis
0.577 0.422 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.577 0.423 0.000
Q25.1 Coarctation of aorta
0.577 0.423 0.000
M87.85 Other osteonecrosis (Pelvic region and thigh)
0.576 0.424 0.000
M13.09 Polyarthritis, unspecified (Site unspecified)
0.576 0.424 0.000
E22.1 Hyperprolactinaemia
0.576 0.424 0.000
M30.0 Polyarteritis nodosa
0.575 0.424 0.000
H70.8 Other mastoiditis and related conditions
0.575 0.425 0.000
H60-H62 Diseases of external ear
0.575 0.425 0.000
M24.27 Disorder of ligament (Ankle and foot)
0.575 0.425 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.574 0.426 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.574 0.426 0.000
M43.08 Spondylolysis (Sacral and sacrococcygeal region)
0.574 0.426 0.000
M43.07 Spondylolysis (Lumbosacral region)
0.574 0.426 0.000
M43.05 Spondylolysis (Thoracolumbar region)
0.574 0.426 0.000
M43.04 Spondylolysis (Thoracic region)
0.574 0.426 0.000
M43.03 Spondylolysis (Cervicothoracic region)
0.574 0.426 0.000
M43.01 Spondylolysis (Occipito-atlanto-axial region)
0.574 0.426 0.000
M43.00 Spondylolysis (Multiple sites in spine)
0.574 0.426 0.000
E04.9 Non-toxic goitre, unspecified
0.573 0.427 0.000
H74.3 Other acquired abnormalities of ear ossicles
0.573 0.427 0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.572 0.427 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.572 0.428 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.571 0.429 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.571 0.429 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.571 0.429 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.571 0.429 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.571 0.429 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.571 0.429 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.571 0.429 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.571 0.429 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.571 0.429 0.000
H74.1 Adhesive middle ear disease
0.570 0.430 0.000
E06.5 Other chronic thyroiditis
0.570 0.430 0.000
E06.4 Drug-induced thyroiditis
0.570 0.430 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.570 0.430 0.000
E06.1 Subacute thyroiditis
0.570 0.430 0.000
E06.0 Acute thyroiditis
0.570 0.430 0.000
M82 Osteoporosis in diseases classified elsewhere
0.569 0.430 0.000
Y00-Y09 Assault
0.569 0.431 0.000
H74.2 Discontinuity and dislocation of ear ossicles
0.567 0.433 0.000
H65.2 Chronic serous otitis media
0.566 0.434 0.000
L44 Other papulosquamous disorders
0.565 0.435 0.000
L41 Parapsoriasis
0.565 0.435 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.565 0.435 0.000
H69 Other disorders of Eustachian tube
0.563 0.437 0.000
L40.1 Generalised pustular psoriasis
0.563 0.437 0.000
H73.1 Chronic myringitis
0.563 0.437 0.000
L20-L30 Dermatitis and eczema
0.563 0.437 0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)
0.562 0.438 0.000
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)
0.562 0.438 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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