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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs72731844
log Bayes Factor = 8.46443
Chromosome 4   position 147,555,879  (GRCh37) Explore rs72731844 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.998 0.002 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.997 0.003 0.000
Y43 Primarily systemic agents
0.997 0.003 0.000
Y43.3 Other antineoplastic drugs
0.994 0.006 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.992 0.008 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.981 0.019 0.000
O16 Unspecified maternal hypertension
0.981 0.019 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.975 0.025 0.000
O36 Maternal care for other known or suspected foetal problems
0.973 0.027 0.000
O80-O84 Delivery
0.968 0.032 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.954 0.046 0.000
N60 Benign mammary dysplasia
0.954 0.046 0.000
N60-N64 Disorders of breast
0.953 0.047 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.953 0.047 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.948 0.052 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.943 0.057 0.000
Chapter XIV Diseases of the genitourinary system
0.940 0.060 0.000
N64 Other disorders of breast
0.939 0.061 0.000
C79 Secondary malignant neoplasm of other sites
0.932 0.068 0.000
O80 Single spontaneous delivery
0.931 0.069 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.930 0.070 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.930 0.070 0.000
L08 Other local infections of skin and subcutaneous tissue
0.929 0.071 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.927 0.073 0.000
C50-C50 Malignant neoplasm of breast
0.925 0.075 0.000
C64-C68 Malignant neoplasms of urinary tract
0.913 0.087 0.000
N60.3 Fibrosclerosis of breast
0.901 0.099 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.901 0.099 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.894 0.106 0.000
O48 Prolonged pregnancy
0.894 0.106 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.893 0.107 0.000
C71 Malignant neoplasm of brain
0.892 0.108 0.000
N60.0 Solitary cyst of breast
0.892 0.108 0.000
Chapter XXI Factors influencing health status and contact with health services
0.888 0.112 0.000
T90 Sequelae of injuries of head
0.886 0.114 0.000
N64.8 Other specified disorders of breast
0.885 0.115 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.884 0.116 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.883 0.117 0.000
O36.6 Maternal care for excessive foetal growth
0.876 0.124 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.875 0.125 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.873 0.127 0.000
Z37 Outcome of delivery
0.872 0.128 0.000
C50 Malignant neoplasm of breast
0.871 0.129 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.868 0.132 0.000
Y43.1 Antineoplastic antimetabolites
0.866 0.134 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.866 0.134 0.000
Z37.0 Single live birth
0.865 0.135 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.865 0.135 0.000
C09 Malignant neoplasm of tonsil
0.864 0.136 0.000
C92 Myeloid leukaemia
0.863 0.137 0.000
C50.3 Lower-inner quadrant of breast
0.857 0.143 0.000
C51-C58 Malignant neoplasms of female genital organs
0.855 0.145 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.852 0.148 0.000
O80.0 Spontaneous vertex delivery
0.852 0.148 0.000
O85-O92 Complications predominantly related to the puerperium
0.852 0.148 0.000
N60.1 Diffuse cystic mastopathy
0.850 0.150 0.000
E70-E90 Metabolic disorders
0.844 0.156 0.000
E20-E35 Disorders of other endocrine glands
0.844 0.156 0.000
Chapter XXII Codes for special purposes
0.843 0.157 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.843 0.157 0.000
O36.5 Maternal care for poor foetal growth
0.842 0.158 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.839 0.161 0.000
S70-S79 Injuries to the hip and thigh
0.838 0.162 0.000
T93 Sequelae of injuries of lower limb
0.837 0.163 0.000
T20 Burn and corrosion of head and neck
0.837 0.163 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.836 0.164 0.000
N60.2 Fibroadenosis of breast
0.834 0.166 0.000
S90-S99 Injuries to the ankle and foot
0.833 0.167 0.000
Y52 Agents primarily affecting the cardiovascular system
0.832 0.168 0.000
O36.4 Maternal care for intra-uterine death
0.830 0.170 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.828 0.172 0.000
C10 Malignant neoplasm of oropharynx
0.827 0.173 0.000
T90.5 Sequelae of intracranial injury
0.826 0.174 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.824 0.176 0.000
O44 Placenta praevia
0.818 0.182 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.818 0.182 0.000
X20-X29 Contact with venomous animals and plants
0.812 0.188 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.810 0.190 0.000
Y00-Y09 Assault
0.809 0.191 0.000
L20-L30 Dermatitis and eczema
0.808 0.192 0.000
O81 Single delivery by forceps and vacuum extractor
0.807 0.193 0.000
C09.9 Tonsil, unspecified
0.800 0.200 0.000
Y40 Systemic antibiotics
0.797 0.203 0.000
N25-N29 Other disorders of kidney and ureter
0.796 0.204 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.796 0.204 0.000
N64.4 Mastodynia
0.795 0.205 0.000
N64.5 Other signs and symptoms in breast
0.793 0.207 0.000
V40-V49 Car occupant injured in transport accident
0.793 0.207 0.000
Z32 Pregnancy examination and test
0.791 0.209 0.000
E27 Other disorders of adrenal gland
0.791 0.209 0.000
O42 Premature rupture of membranes
0.788 0.212 0.000
S20-S29 Injuries to the thorax
0.788 0.212 0.000
Z39 Postpartum care and examination
0.787 0.213 0.000
O80.8 Other single spontaneous delivery
0.787 0.213 0.000
Y43.0 Antiallergic and antiemetic drugs
0.786 0.214 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.784 0.216 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.782 0.218 0.000
N60.9 Benign mammary dysplasia, unspecified
0.781 0.219 0.000
O00-O08 Pregnancy with abortive outcome
0.780 0.220 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.780 0.220 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.779 0.221 0.000
C92.0 Acute myeloid leukaemia
0.779 0.221 0.000
O34.1 Maternal care for tumour of corpus uteri
0.779 0.221 0.000
S10-S19 Injuries to the neck
0.779 0.221 0.000
Y84.0 Cardiac catheterisation
0.777 0.223 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.776 0.224 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.775 0.225 0.000
C78.2 Secondary malignant neoplasm of pleura
0.775 0.225 0.000
T90.9 Sequelae of unspecified injury of head
0.774 0.226 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.773 0.227 0.000
O24 Diabetes mellitus in pregnancy
0.773 0.227 0.000
W50-W64 Exposure to animate mechanical forces
0.773 0.227 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.772 0.228 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.772 0.228 0.000
C71.9 Brain, unspecified
0.772 0.228 0.000
O20 Haemorrhage in early pregnancy
0.771 0.229 0.000
Chapter I Certain infectious and parasitic diseases
0.770 0.230 0.000
O80.9 Single spontaneous delivery, unspecified
0.769 0.231 0.000
L08.8 Other specified local infections of skin and subcutaneous tissue
0.766 0.234 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.766 0.234 0.000
N10-N16 Renal tubulo-interstitial diseases
0.765 0.235 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.764 0.236 0.000
N60.4 Mammary duct ectasia
0.764 0.236 0.000
E40-E46 Malnutrition
0.763 0.237 0.000
V01-V09 Pedestrian injured in transport accident
0.761 0.239 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.761 0.239 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.760 0.240 0.000
S91 Open wound of ankle and foot
0.758 0.242 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.755 0.245 0.000
A30-A49 Other bacterial diseases
0.754 0.246 0.000
O47 False labour
0.751 0.249 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.750 0.250 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.749 0.251 0.000
Q60-Q64 Congenital malformations of the urinary system
0.748 0.252 0.000
W00-W19 Falls
0.748 0.252 0.000
C54 Malignant neoplasm of corpus uteri
0.747 0.253 0.000
T20.2 Burn of second degree of head and neck
0.747 0.253 0.000
O36.8 Maternal care for other specified foetal problems
0.747 0.253 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.746 0.254 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.745 0.255 0.000
X50-X57 Overexertion, travel and privation
0.745 0.255 0.000
L50-L54 Urticaria and erythema
0.745 0.255 0.000
Y84.2 Radiological procedure and radiotherapy
0.745 0.255 0.000
L40-L45 Papulosquamous disorders
0.744 0.256 0.000
E78.5 Hyperlipidaemia, unspecified
0.744 0.256 0.000
T93.2 Sequelae of other fractures of lower limb
0.744 0.256 0.000
Y43.4 Immunosuppressive agents
0.743 0.257 0.000
L03 Cellulitis
0.743 0.257 0.000
C71.2 Temporal lobe
0.742 0.258 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.741 0.259 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.740 0.260 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.738 0.261 0.000
C66 Malignant neoplasm of ureter
0.736 0.264 0.000
O40 Polyhydramnios
0.736 0.264 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.736 0.264 0.000
C10.9 Oropharynx, unspecified
0.736 0.264 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.736 0.264 0.000
N64.9 Disorder of breast, unspecified
0.735 0.265 0.000
L05 Pilonidal cyst
0.734 0.265 0.000
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons
0.734 0.266 0.000
C50.9 Breast, unspecified
0.733 0.267 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.731 0.269 0.000
Q50-Q56 Congenital malformations of genital organs
0.730 0.270 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.729 0.271 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.729 0.271 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.729 0.271 0.000
C69 Malignant neoplasm of eye and adnexa
0.728 0.272 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.728 0.272 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.727 0.273 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.727 0.273 0.000
A41 Other septicaemia
0.727 0.273 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.726 0.274 0.000
X10-X19 Contact with heat and hot substances
0.726 0.274 0.000
T91 Sequelae of injuries of neck and trunk
0.725 0.275 0.000
Z37.1 Single stillbirth
0.724 0.276 0.000
S80-S89 Injuries to the knee and lower leg
0.723 0.277 0.000
X60-X84 Intentional self-harm
0.723 0.277 0.000
C92.1 Chronic myeloid leukaemia
0.722 0.277 0.000
C04 Malignant neoplasm of floor of mouth
0.722 0.278 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.722 0.278 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.722 0.278 0.000
Z39.1 Care and examination of lactating mother
0.721 0.279 0.000
L85 Other epidermal thickening
0.721 0.279 0.000
O34.4 Maternal care for other abnormalities of cervix
0.720 0.280 0.000
N64.1 Fat necrosis of breast
0.720 0.280 0.000
O43 Placental disorders
0.719 0.280 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.718 0.282 0.000
T79-T79 Certain early complications of trauma
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
L84 Corns and callosities
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
W75-W84 Other accidental threats to breathing
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V10-V19 Pedal cyclist injured in transport accident
0.716 0.284 0.000
C01 Malignant neoplasm of base of tongue
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
Y59 Other and unspecified vaccines and biological substances
0.715 0.284 0.000
Y58 Bacterial vaccines
0.715 0.284 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.715 0.284 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.715 0.284 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.715 0.284 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.715 0.284 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.715 0.284 0.000
O45 Premature separation of placenta [abruptio placentae]
0.715 0.285 0.000
O33 Maternal care for known or suspected disproportion
0.715 0.285 0.000
O31 Complications specific to multiple gestation
0.715 0.285 0.000
Y43.9 Primarily systemic agent, unspecified
0.715 0.285 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.715 0.285 0.000
Y43.6 Enzymes, not elsewhere classified
0.715 0.285 0.000
Y43.5 Acidifying and alkalising agents
0.715 0.285 0.000
Y43.2 Antineoplastic natural products
0.715 0.285 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.714 0.286 0.000
L03.2 Cellulitis of face
0.712 0.288 0.000
Z51 Other medical care
0.712 0.288 0.000
C71.1 Frontal lobe
0.712 0.288 0.000
O15 Eclampsia
0.711 0.289 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.711 0.289 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.711 0.289 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.711 0.289 0.000
Y42.5 Other oestrogens and progestogens
0.711 0.289 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.710 0.290 0.000
Z32.1 Pregnancy confirmed
0.710 0.290 0.000
C71.4 Occipital lobe
0.710 0.290 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.710 0.290 0.000
O86 Other puerperal infections
0.708 0.292 0.000
E22 Hyperfunction of pituitary gland
0.708 0.292 0.000
Y48 Anaesthetics and therapeutic gases
0.707 0.293 0.000
O36.3 Maternal care for signs of foetal hypoxia
0.706 0.294 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.705 0.295 0.000
A41.9 Septicaemia, unspecified
0.705 0.295 0.000
L10-L14 Bullous disorders
0.704 0.296 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.703 0.297 0.000
O20.0 Threatened abortion
0.700 0.300 0.000
S71 Open wound of hip and thigh
0.700 0.300 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.699 0.301 0.000
T31 Burns classified according to extent of body surface involved
0.699 0.301 0.000
S31 Open wound of abdomen, lower back and pelvis
0.698 0.302 0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy
0.698 0.302 0.000
O36.2 Maternal care for hydrops foetalis
0.698 0.302 0.000
O36.1 Maternal care for other isoimmunisation
0.698 0.302 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.696 0.304 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.696 0.304 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.695 0.305 0.000
O84 Multiple delivery
0.694 0.306 0.000
O83 Other assisted single delivery
0.694 0.306 0.000
O44.0 Placenta praevia specified as without haemorrhage
0.694 0.306 0.000
O24.4 Diabetes mellitus arising in pregnancy
0.693 0.307 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.693 0.307 0.000
T23 Burn and corrosion of wrist and hand
0.693 0.307 0.000
C85.1 B-cell lymphoma, unspecified
0.693 0.307 0.000
S00-S09 Injuries to the head
0.692 0.308 0.000
E27.1 Primary adrenocortical insufficiency
0.691 0.309 0.000
Y84.4 Aspiration of fluid
0.691 0.309 0.000
O81.3 Other and unspecified forceps delivery
0.691 0.309 0.000
S32 Fracture of lumbar spine and pelvis
0.691 0.309 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.690 0.310 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.690 0.310 0.000
S72 Fracture of femur
0.688 0.312 0.000
O82 Single delivery by Caesarean section
0.687 0.313 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.686 0.314 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.684 0.316 0.000
C13 Malignant neoplasm of hypopharynx
0.684 0.316 0.000
C11 Malignant neoplasm of nasopharynx
0.684 0.316 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.684 0.316 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.684 0.316 0.000
C05 Malignant neoplasm of palate
0.684 0.316 0.000
C03 Malignant neoplasm of gum
0.684 0.316 0.000
C00 Malignant neoplasm of lip
0.684 0.316 0.000
C12 Malignant neoplasm of pyriform sinus
0.684 0.316 0.000
Z35 Supervision of high-risk pregnancy
0.684 0.316 0.000
V80-V89 Other land transport accidents
0.683 0.317 0.000
L04 Acute lymphadenitis
0.683 0.317 0.000
L01 Impetigo
0.683 0.317 0.000
L00 Staphylococcal scalded skin syndrome
0.683 0.317 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.683 0.317 0.000
T14 Injury of unspecified body region
0.681 0.319 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.681 0.319 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.680 0.320 0.000
T95 Sequelae of burns, corrosions and frostbite
0.680 0.320 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.680 0.320 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.680 0.320 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.680 0.320 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.678 0.322 0.000
X23 Contact with hornets, wasps and bees
0.677 0.323 0.000
C79.6 Secondary malignant neoplasm of ovary
0.677 0.323 0.000
Z51.3 Blood transfusion without reported diagnosis
0.676 0.324 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.676 0.324 0.000
C70 Malignant neoplasm of meninges
0.676 0.324 0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.675 0.325 0.000
O21 Excessive vomiting in pregnancy
0.675 0.325 0.000
O28 Abnormal findings on antenatal screening of mother
0.674 0.325 0.000
O41 Other disorders of amniotic fluid and membranes
0.674 0.326 0.000
N60.8 Other benign mammary dysplasias
0.674 0.326 0.000
D45 Polycythaemia vera
0.674 0.326 0.000
N64.3 Galactorrhoea not associated with childbirth
0.673 0.327 0.000
N64.2 Atrophy of breast
0.673 0.327 0.000
N64.0 Fissure and fistula of nipple
0.673 0.327 0.000
Y04 Assault by bodily force
0.673 0.327 0.000
E86 Volume depletion
0.672 0.328 0.000
E46 Unspecified protein-energy malnutrition
0.669 0.331 0.000
C54.1 Endometrium
0.669 0.331 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.668 0.332 0.000
O80.1 Spontaneous breech delivery
0.668 0.332 0.000
C67 Malignant neoplasm of bladder
0.667 0.333 0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified
0.667 0.333 0.000
O34.8 Maternal care for other abnormalities of pelvic organs
0.667 0.333 0.000
O34.6 Maternal care for abnormality of vagina
0.667 0.333 0.000
O34.5 Maternal care for other abnormalities of gravid uterus
0.667 0.333 0.000
O34.3 Maternal care for cervical incompetence
0.667 0.333 0.000
O34.0 Maternal care for congenital malformation of uterus
0.667 0.333 0.000
T20.1 Burn of first degree of head and neck
0.667 0.333 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.667 0.333 0.000
C95 Leukaemia of unspecified cell type
0.667 0.333 0.000
C94 Other leukaemias of specified cell type
0.667 0.333 0.000
C93 Monocytic leukaemia
0.667 0.333 0.000
C86 Other specified types of T/NK-cell lymphoma
0.667 0.333 0.000
L28 Lichen simplex chronicus and prurigo
0.667 0.333 0.000
L08.1 Erythrasma
0.666 0.334 0.000
L08.0 Pyoderma
0.666 0.334 0.000
Q63 Other congenital malformations of kidney
0.666 0.334 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.665 0.335 0.000
T25 Burn and corrosion of ankle and foot
0.665 0.335 0.000
T21 Burn and corrosion of trunk
0.665 0.335 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.665 0.335 0.000
S36 Injury of intra-abdominal organs
0.662 0.338 0.000
O36.9 Maternal care for foetal problem, unspecified
0.662 0.338 0.000
O85 Puerperal sepsis
0.661 0.338 0.000
C50.5 Lower-outer quadrant of breast
0.661 0.339 0.000
V49 Car occupant injured in other and unspecified transport accidents
0.659 0.340 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.659 0.341 0.000
E74 Other disorders of carbohydrate metabolism
0.659 0.341 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.659 0.341 0.000
N10 Acute tubulo-interstitial nephritis
0.657 0.343 0.000
C91 Lymphoid leukaemia
0.657 0.343 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.657 0.343 0.000
E88 Other metabolic disorders
0.656 0.344 0.000
Z30 Contraceptive management
0.656 0.344 0.000
E24 Cushing's syndrome
0.656 0.344 0.000
V20-V29 Motorcycle rider injured in transport accident
0.655 0.345 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.655 0.345 0.000
C65 Malignant neoplasm of renal pelvis
0.655 0.345 0.000
C07 Malignant neoplasm of parotid gland
0.654 0.346 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.654 0.346 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.654 0.346 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.654 0.346 0.000
A49 Bacterial infection of unspecified site
0.654 0.346 0.000
T09 Other injuries of spine and trunk, level unspecified
0.653 0.347 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.653 0.347 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.653 0.347 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.652 0.348 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.651 0.349 0.000
Y44 Agents primarily affecting blood constituents
0.650 0.349 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.650 0.350 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.649 0.351 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.649 0.351 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.649 0.351 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.649 0.351 0.000
L93 Lupus erythematosus
0.648 0.352 0.000
C71.3 Parietal lobe
0.648 0.352 0.000
C77.1 Intrathoracic lymph nodes
0.648 0.352 0.000
Z31 Procreative management
0.648 0.352 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.647 0.352 0.000
T93.0 Sequelae of open wound of lower limb
0.648 0.352 0.000
S06 Intracranial injury
0.646 0.354 0.000
W10 Fall on and from stairs and steps
0.646 0.354 0.000
S86 Injury of muscle and tendon at lower leg level
0.646 0.354 0.000
Y57 Other and unspecified drugs and medicaments
0.644 0.356 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.644 0.356 0.000
T98 Sequelae of other and unspecified effects of external causes
0.643 0.357 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.643 0.357 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.641 0.359 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.641 0.359 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.641 0.359 0.000
C71.8 Overlapping lesion of brain
0.640 0.360 0.000
C71.7 Brain stem
0.640 0.360 0.000
C71.6 Cerebellum
0.640 0.360 0.000
C71.5 Cerebral ventricle
0.640 0.360 0.000
C71.0 Cerebrum, except lobes and ventricles
0.640 0.360 0.000
U89 Agent resistant to other and unspecified antibiotics
0.638 0.362 0.000
C80 Malignant neoplasm without specification of site
0.638 0.362 0.000
Y40.0 Penicillins
0.638 0.362 0.000
Q51 Congenital malformations of uterus and cervix
0.638 0.362 0.000
C34 Malignant neoplasm of bronchus and lung
0.637 0.363 0.000
Q80-Q89 Other congenital malformations
0.637 0.363 0.000
D47.1 Chronic myeloproliferative disease
0.637 0.363 0.000
N26 Unspecified contracted kidney
0.636 0.364 0.000
T13 Other injuries of lower limb, level unspecified
0.636 0.364 0.000
T90.8 Sequelae of other specified injuries of head
0.635 0.365 0.000
T90.3 Sequelae of injury of cranial nerves
0.635 0.365 0.000
T90.1 Sequelae of open wound of head
0.635 0.365 0.000
T90.0 Sequelae of superficial injury of head
0.635 0.365 0.000
Z53.9 Procedure not carried out, unspecified reason
0.635 0.365 0.000
S22.4 Multiple fractures of ribs
0.635 0.365 0.000
S91.3 Open wound of other parts of foot
0.635 0.365 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.634 0.366 0.000
C84.4 Peripheral T-cell lymphoma
0.634 0.366 0.000
O29 Complications of anaesthesia during pregnancy
0.633 0.366 0.000
O22 Venous complications in pregnancy
0.633 0.366 0.000
O25 Malnutrition in pregnancy
0.633 0.366 0.000
Z38 Liveborn infants according to place of birth
0.633 0.367 0.000
D47.4 Osteomyelofibrosis
0.632 0.368 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.632 0.368 0.000
C88 Malignant immunoproliferative diseases
0.632 0.368 0.000
L30 Other dermatitis
0.631 0.369 0.000
S40-S49 Injuries to the shoulder and upper arm
0.631 0.369 0.000
C73 Malignant neoplasm of thyroid gland
0.630 0.370 0.000
L20 Atopic dermatitis
0.629 0.371 0.000
D37.2 Small intestine
0.628 0.371 0.000
C50.0 Nipple and areola
0.628 0.372 0.000
N62 Hypertrophy of breast
0.628 0.372 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.627 0.373 0.000
O90 Complications of the puerperium, not elsewhere classified
0.627 0.373 0.000
C53 Malignant neoplasm of cervix uteri
0.627 0.373 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.627 0.373 0.000
L43 Lichen planus
0.627 0.373 0.000
S32.5 Fracture of pubis
0.627 0.373 0.000
N61 Inflammatory disorders of breast
0.626 0.374 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.625 0.375 0.000
Z37.9 Outcome of delivery unspecified
0.625 0.375 0.000
Z37.7 Other multiple births, all stillborn
0.625 0.375 0.000
Z37.6 Other multiple births, some liveborn
0.625 0.375 0.000
Z37.5 Other multiple births, all liveborn
0.625 0.375 0.000
Z37.4 Twins, both stillborn
0.625 0.375 0.000
Z37.3 Twins, one liveborn and one stillborn
0.625 0.375 0.000
T66-T78 Other and unspecified effects of external causes
0.625 0.375 0.000
C50.6 Axillary tail of breast
0.625 0.375 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.624 0.376 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.624 0.376 0.000
S91.1 Open wound of toe(s) without damage to nail
0.623 0.377 0.000
T93.1 Sequelae of fracture of femur
0.623 0.377 0.000
D37.3 Appendix
0.623 0.377 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.623 0.377 0.000
S37 Injury of urinary and pelvic organs
0.623 0.377 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.623 0.377 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.623 0.377 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.623 0.377 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.620 0.380 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.620 0.380 0.000
Q35-Q37 Cleft lip and cleft palate
0.620 0.380 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.620 0.380 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.620 0.380 0.000
Z49 Care involving dialysis
0.620 0.380 0.000
E78.8 Other disorders of lipoprotein metabolism
0.620 0.380 0.000
C09.8 Overlapping lesion of tonsil
0.619 0.380 0.000
C09.1 Tonsillar pillar (anterior) (posterior)
0.619 0.380 0.000
C09.0 Tonsillar fossa
0.619 0.380 0.000
C92.9 Myeloid leukaemia, unspecified
0.619 0.381 0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.619 0.381 0.000
C92.7 Other myeloid leukaemia
0.619 0.381 0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.619 0.381 0.000
C92.5 Acute myelomonocytic leukaemia
0.619 0.381 0.000
C92.4 Acute promyelocytic leukaemia
0.619 0.381 0.000
C92.3 Myeloid sarcoma
0.619 0.381 0.000
C92.2 Subacute myeloid leukaemia
0.619 0.381 0.000
A15-A19 Tuberculosis
0.619 0.381 0.000
T45.0 Antiallergic and antiemetic drugs
0.618 0.382 0.000
C84.5 Other and unspecified T-cell lymphomas
0.618 0.382 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.618 0.382 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.618 0.382 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.618 0.382 0.000
N63 Unspecified lump in breast
0.616 0.384 0.000
Z48 Other surgical follow-up care
0.615 0.385 0.000
E22.0 Acromegaly and pituitary gigantism
0.614 0.386 0.000
C58 Malignant neoplasm of placenta
0.613 0.387 0.000
C52 Malignant neoplasm of vagina
0.613 0.387 0.000
L81 Other disorders of pigmentation
0.613 0.387 0.000
O03 Spontaneous abortion
0.613 0.387 0.000
Y40.9 Systemic antibiotic, unspecified
0.612 0.388 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.611 0.389 0.000
C85.0 Lymphosarcoma
0.611 0.389 0.000
O92 Other disorders of breast and lactation associated with childbirth
0.611 0.389 0.000
O91 Infections of breast associated with childbirth
0.611 0.389 0.000
O89 Complications of anaesthesia during the puerperium
0.611 0.389 0.000
O88 Obstetric embolism
0.611 0.389 0.000
O87 Venous complications in the puerperium
0.611 0.389 0.000
S91.0 Open wound of ankle
0.610 0.390 0.000
W50 Hit, struck, kicked, twisted, bitten or scratched by another person
0.610 0.390 0.000
T31.0 Burns involving less than 10% of body surface
0.610 0.390 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.610 0.390 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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