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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs727428
log Bayes Factor = 0.234682
Chromosome 17   position 7,537,792  (GRCh37) Explore rs727428 on Ensembl!
Variant rs727428 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K62.7 Radiation proctitis
0.000 0.662 0.338
H25.1 Senile nuclear cataract
0.186 0.814 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.155 0.845 0.000
H18 Other disorders of cornea
0.153 0.847 0.000
H25-H28 Disorders of lens
0.151 0.849 0.000
H25 Senile cataract
0.150 0.850 0.000
H26.4 After-cataract
0.145 0.855 0.000
H26 Other cataract
0.145 0.855 0.000
H18.9 Disorder of cornea, unspecified
0.144 0.856 0.000
H21 Other disorders of iris and ciliary body
0.143 0.857 0.000
H17 Corneal scars and opacities
0.142 0.858 0.000
Chapter VII Diseases of the eye and adnexa
0.141 0.859 0.000
H43-H45 Disorders of vitreous body and globe
0.136 0.864 0.000
H18.5 Hereditary corneal dystrophies
0.135 0.865 0.000
H44 Disorders of globe
0.134 0.866 0.000
H44.1 Other endophthalmitis
0.131 0.869 0.000
H17.9 Corneal scar and opacity, unspecified
0.130 0.869 0.000
H10-H13 Disorders of conjunctiva
0.130 0.870 0.000
H26.2 Complicated cataract
0.129 0.871 0.000
H11.4 Other conjunctival vascular disorders and cysts
0.129 0.871 0.000
H21.1 Other vascular disorders of iris and ciliary body
0.128 0.872 0.000
H11 Other disorders of conjunctiva
0.127 0.873 0.000
H21.0 Hyphaema
0.127 0.873 0.000
H18.3 Changes in corneal membranes
0.125 0.875 0.000
H18.4 Corneal degeneration
0.124 0.876 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.118 0.882 0.000
H15 Disorders of sclera
0.116 0.884 0.000
H18.2 Other corneal oedema
0.116 0.884 0.000
H26.8 Other specified cataract
0.115 0.885 0.000
H44.2 Degenerative myopia
0.115 0.885 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.115 0.885 0.000
H21.4 Pupillary membranes
0.111 0.889 0.000
H17.8 Other corneal scars and opacities
0.111 0.889 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.110 0.890 0.000
H44.4 Hypotony of eye
0.109 0.891 0.000
H18.6 Keratoconus
0.108 0.892 0.000
H21.5 Other adhesions and disruptions of iris and ciliary body
0.108 0.892 0.000
H44.0 Purulent endophthalmitis
0.108 0.892 0.000
H27 Other disorders of lens
0.107 0.893 0.000
H20 Iridocyclitis
0.105 0.895 0.000
H26.0 Infantile, juvenile and presenile cataract
0.105 0.895 0.000
H55-H59 Other disorders of eye and adnexa
0.105 0.895 0.000
H18.7 Other corneal deformities
0.105 0.895 0.000
H18.8 Other specified disorders of cornea
0.104 0.896 0.000
H11.9 Disorder of conjunctiva, unspecified
0.104 0.896 0.000
H11.1 Conjunctival degenerations and deposits
0.104 0.896 0.000
H21.3 Cyst of iris, ciliary body and anterior chamber
0.103 0.897 0.000
H18.0 Corneal pigmentations and deposits
0.102 0.898 0.000
H17.1 Other central corneal opacity
0.102 0.898 0.000
H17.0 Adherent leukoma
0.102 0.898 0.000
H25.2 Senile cataract, morgagnian type
0.101 0.899 0.000
H18.1 Bullous keratopathy
0.100 0.900 0.000
H21.9 Disorder of iris and ciliary body, unspecified
0.098 0.902 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.097 0.903 0.000
H55 Nystagmus and other irregular eye movements
0.097 0.903 0.000
H44.6 Retained (old) intraocular foreign body, magnetic
0.096 0.904 0.000
H44.3 Other degenerative disorders of globe
0.096 0.904 0.000
H26.3 Drug-induced cataract
0.095 0.904 0.000
H21.8 Other specified disorders of iris and ciliary body
0.094 0.906 0.000
H27.0 Aphakia
0.092 0.908 0.000
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere
0.091 0.908 0.000
H44.9 Disorder of globe, unspecified
0.091 0.909 0.000
H20.8 Other iridocyclitis
0.091 0.909 0.000
H15.8 Other disorders of sclera
0.090 0.910 0.000
H19.1 Herpesviral keratitis and keratoconjunctivitis
0.089 0.911 0.000
H16 Keratitis
0.089 0.911 0.000
H44.7 Retained (old) intraocular foreign body, nonmagnetic
0.087 0.912 0.000
H43 Disorders of vitreous body
0.087 0.913 0.000
H21.2 Degeneration of iris and ciliary body
0.086 0.914 0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere
0.086 0.914 0.000
H25.9 Senile cataract, unspecified
0.085 0.915 0.000
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere
0.084 0.915 0.000
H19.0 Scleritis and episcleritis in diseases classified elsewhere
0.084 0.915 0.000
H15.1 Episcleritis
0.084 0.916 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.083 0.917 0.000
H11.8 Other specified disorders of conjunctiva
0.083 0.917 0.000
H44.8 Other disorders of globe
0.083 0.917 0.000
H22.1 Iridocyclitis in other diseases classified elsewhere
0.083 0.917 0.000
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere
0.082 0.917 0.000
H15.9 Disorder of sclera, unspecified
0.082 0.917 0.000
H44.5 Degenerated conditions of globe
0.082 0.917 0.000
H10 Conjunctivitis
0.082 0.918 0.000
H11.0 Pterygium
0.082 0.918 0.000
H15.0 Scleritis
0.081 0.919 0.000
H28.0 Diabetic cataract
0.081 0.919 0.000
H11.2 Conjunctival scars
0.081 0.919 0.000
H13 Disorders of conjunctiva in diseases classified elsewhere
0.081 0.919 0.000
H28.8 Other disorders of lens in diseases classified elsewhere
0.079 0.921 0.000
H28.2 Cataract in other diseases classified elsewhere
0.079 0.921 0.000
H28.1 Cataract in other endocrine, nutritional and metabolic diseases
0.079 0.921 0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere
0.078 0.922 0.000
H27.9 Disorder of lens, unspecified
0.077 0.923 0.000
H20.1 Chronic iridocyclitis
0.076 0.924 0.000
H20.2 Lens-induced iridocyclitis
0.076 0.924 0.000
H43.2 Crystalline deposits in vitreous body
0.075 0.925 0.000
G82.2 Paraplegia, unspecified
0.000 0.925 0.075
H50 Other strabismus
0.073 0.927 0.000
H27.8 Other specified disorders of lens
0.073 0.927 0.000
H43.3 Other vitreous opacities
0.072 0.928 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.071 0.929 0.000
H20.0 Acute and subacute iridocyclitis
0.070 0.930 0.000
H45.8 Other disorders of vitreous body and globe in diseases classified elsewhere
0.070 0.930 0.000
H45.1 Endophthalmitis in diseases classified elsewhere
0.070 0.930 0.000
H45.0 Vitreous haemorrhage in diseases classified elsewhere
0.070 0.930 0.000
H16.1 Other superficial keratitis without conjunctivitis
0.069 0.931 0.000
H16.8 Other keratitis
0.067 0.933 0.000
H16.4 Corneal neovascularisation
0.066 0.933 0.000
H10.3 Acute conjunctivitis, unspecified
0.066 0.934 0.000
H40-H42 Glaucoma
0.064 0.936 0.000
H16.2 Keratoconjunctivitis
0.064 0.936 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.063 0.936 0.000
H43.0 Vitreous prolapse
0.063 0.936 0.000
H50.0 Convergent concomitant strabismus
0.063 0.937 0.000
G82 Paraplegia and tetraplegia
0.000 0.938 0.062
H50.2 Vertical strabismus
0.061 0.939 0.000
H10.5 Blepharoconjunctivitis
0.061 0.939 0.000
H50.6 Mechanical strabismus
0.059 0.941 0.000
H10.8 Other conjunctivitis
0.059 0.941 0.000
H10.2 Other acute conjunctivitis
0.059 0.941 0.000
H10.0 Mucopurulent conjunctivitis
0.059 0.941 0.000
H26.1 Traumatic cataract
0.059 0.941 0.000
H53-H54 Visual disturbances and blindness
0.059 0.941 0.000
H10.1 Acute atopic conjunctivitis
0.058 0.942 0.000
H13.8 Other disorders of conjunctiva in diseases classified elsewhere
0.058 0.942 0.000
H13.2 Conjunctivitis in other diseases classified elsewhere
0.058 0.942 0.000
H13.0 Filarial infection of conjunctiva
0.058 0.942 0.000
H43.1 Vitreous haemorrhage
0.058 0.942 0.000
H49 Paralytic strabismus
0.058 0.942 0.000
H59.8 Other postprocedural disorders of eye and adnexa
0.057 0.943 0.000
H16.9 Keratitis, unspecified
0.057 0.943 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.056 0.943 0.001
G82.1 Spastic paraplegia
0.000 0.943 0.057
H16.3 Interstitial and deep keratitis
0.056 0.944 0.000
H51 Other disorders of binocular movement
0.054 0.946 0.000
H50.4 Other and unspecified heterotropia
0.054 0.946 0.000
H50.1 Divergent concomitant strabismus
0.054 0.946 0.000
H13.3 Ocular pemphigoid
0.053 0.947 0.000
H50.3 Intermittent heterotropia
0.052 0.947 0.000
H27.1 Dislocation of lens
0.052 0.948 0.000
H49.1 Fourth [trochlear] nerve palsy
0.052 0.948 0.000
H57 Other disorders of eye and adnexa
0.052 0.948 0.000
H59.0 Vitreous syndrome following cataract surgery
0.052 0.948 0.000
H13.1 Conjunctivitis in infectious and parasitic diseases classified elsewhere
0.051 0.949 0.000
G82.5 Tetraplegia, unspecified
0.000 0.950 0.050
H25.8 Other senile cataract
0.050 0.950 0.000
H11.3 Conjunctival haemorrhage
0.049 0.951 0.000
H50.9 Strabismus, unspecified
0.048 0.952 0.000
H10.4 Chronic conjunctivitis
0.048 0.952 0.000
G82.4 Spastic tetraplegia
0.000 0.953 0.047
H50.5 Heterophoria
0.047 0.953 0.000
H10.9 Conjunctivitis, unspecified
0.046 0.954 0.000
H42 Glaucoma in diseases classified elsewhere
0.046 0.954 0.000
H58.9 Other specified disorders of eye and adnexa in diseases classified elsewhere
0.046 0.954 0.000
H58.1 Visual disturbances in diseases classified elsewhere
0.046 0.954 0.000
H58.0 Anomalies of pupillary function in diseases classified elsewhere
0.046 0.954 0.000
H16.0 Corneal ulcer
0.046 0.954 0.000
G82.3 Flaccid tetraplegia
0.000 0.955 0.044
G82.0 Flaccid paraplegia
0.000 0.955 0.044
H20.9 Iridocyclitis, unspecified
0.044 0.956 0.000
H43.9 Disorder of vitreous body, unspecified
0.044 0.956 0.000
H50.8 Other specified strabismus
0.043 0.956 0.000
H49.4 Progressive external ophthalmoplegia
0.042 0.958 0.000
H49.8 Other paralytic strabismus
0.042 0.958 0.000
H51.9 Disorder of binocular movement, unspecified
0.042 0.958 0.000
H49.3 Total (external) ophthalmoplegia
0.042 0.958 0.000
H54 Blindness and low vision
0.042 0.958 0.000
H57.9 Disorder of eye and adnexa, unspecified
0.041 0.959 0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.041 0.959 0.001
H57.0 Anomalies of pupillary function
0.041 0.959 0.000
H51.8 Other specified disorders of binocular movement
0.039 0.961 0.000
H51.1 Convergence insufficiency and excess
0.039 0.961 0.000
H51.0 Palsy of conjugate gaze
0.039 0.961 0.000
H54.7 Unspecified visual loss
0.039 0.961 0.000
F33.9 Recurrent depressive disorder, unspecified
0.038 0.962 0.000
H49.2 Sixth [abducent] nerve palsy
0.037 0.963 0.000
H59.9 Postprocedural disorder of eye and adnexa, unspecified
0.035 0.965 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.034 0.965 0.001
H49.9 Paralytic strabismus, unspecified
0.034 0.966 0.000
H58.8 Visual disturbances in diseases classified elsewhere
0.034 0.966 0.000
H54.1 Blindness, one eye, low vision, other eye
0.033 0.966 0.000
H42.8 Glaucoma in other diseases classified elsewhere
0.033 0.967 0.000
H42.0 Glaucoma in endocrine, nutritional and metabolic diseases
0.033 0.967 0.000
H54.2 Low vision, both eyes
0.033 0.967 0.000
H26.9 Cataract, unspecified
0.032 0.968 0.000
H47.3 Other disorders of optic disk
0.032 0.968 0.000
H54.5 Low vision, one eye
0.032 0.968 0.000
H54.6 Unqualified visual loss, one eye
0.031 0.969 0.000
H54.3 Unqualified visual loss, both eyes
0.030 0.970 0.000
H48.8 Other disorders of optic nerve and visual pathways in diseases classified elsewhere
0.029 0.970 0.001
H48.1 Retrobulbar neuritis in diseases classified elsewhere
0.029 0.970 0.001
H48.0 Optic atrophy in diseases classified elsewhere
0.029 0.970 0.001
H25.0 Senile incipient cataract
0.029 0.971 0.000
H49.0 Third [oculomotor] nerve palsy
0.029 0.971 0.000
H51.2 Internuclear ophthalmoplegia
0.028 0.971 0.001
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.028 0.972 0.000
H43.8 Other disorders of vitreous body
0.028 0.972 0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)
0.027 0.973 0.000
H54.9 Unspecified visual impairment (binocular)
0.027 0.973 0.000
H57.8 Other specified disorders of eye and adnexa
0.026 0.974 0.000
H47.5 Disorders of other visual pathways
0.026 0.974 0.001
H47.7 Disorder of visual pathways, unspecified
0.025 0.975 0.001
H47.6 Disorders of visual cortex
0.025 0.975 0.001
H47.4 Disorders of optic chiasm
0.025 0.975 0.001
M80.9 Unspecified osteoporosis with pathological fracture
0.024 0.976 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.023 0.976 0.000
H05 Disorders of orbit
0.024 0.976 0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)
0.022 0.978 0.000
H47.0 Disorders of optic nerve, not elsewhere classified
0.020 0.979 0.001
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.020 0.980 0.000
H01 Other inflammation of eyelid
0.020 0.980 0.000
H03.1 Involvement of eyelid in other infectious diseases classified elsewhere
0.020 0.980 0.000
H05.9 Disorder of orbit, unspecified
0.020 0.980 0.000
H05.3 Deformity of orbit
0.019 0.981 0.000
H05.1 Chronic inflammatory disorders of orbit
0.019 0.981 0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)
0.018 0.982 0.000
H05.0 Acute inflammation of orbit
0.017 0.982 0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)
0.017 0.982 0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)
0.017 0.982 0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)
0.017 0.982 0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)
0.017 0.982 0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)
0.017 0.982 0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)
0.017 0.982 0.000
H05.4 Enophthalmos
0.017 0.982 0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)
0.017 0.983 0.000
H03.8 Involvement of eyelid in other diseases classified elsewhere
0.017 0.983 0.000
H03.0 Parasitic infestation of eyelid in diseases classified elsewhere
0.017 0.983 0.000
H05.5 Retained (old) foreign body following penetrating wound of orbit
0.017 0.983 0.000
H01.9 Inflammation of eyelid, unspecified
0.017 0.983 0.000
H05.8 Other disorders of orbit
0.016 0.984 0.000
M80 Osteoporosis with pathological fracture
0.016 0.984 0.000
H01.1 Non-infectious dermatoses of eyelid
0.016 0.984 0.000
H47.1 Papilloedema, unspecified
0.015 0.984 0.001
H57.1 Ocular pain
0.015 0.984 0.000
H01.0 Blepharitis
0.015 0.985 0.000
H52 Disorders of refraction and accommodation
0.015 0.985 0.000
C67.5 Bladder neck
0.000 0.985 0.015
H06.3 Other disorders of orbit in diseases classified elsewhere
0.015 0.985 0.000
H06.1 Parasitic infestation of orbit in diseases classified elsewhere
0.015 0.985 0.000
H06.0 Disorders of lachrymal system in diseases classified elsewhere
0.015 0.985 0.000
H06.2 Dysthyroid exophthalmos
0.015 0.985 0.000
H47.2 Optic atrophy
0.014 0.985 0.001
H46 Optic neuritis
0.013 0.986 0.001
H54.0 Blindness, both eyes
0.014 0.986 0.000
C67.4 Posterior wall of bladder
0.000 0.986 0.014
M80.5 Idiopathic osteoporosis with pathological fracture
0.014 0.986 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.000 0.986 0.014
C67 Malignant neoplasm of bladder
0.000 0.987 0.013
C49.3 Connective and soft tissue of thorax
0.000 0.987 0.013
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.013 0.987 0.000
H05.2 Exophthalmic conditions
0.012 0.988 0.000
C49.0 Connective and soft tissue of head, face and neck
0.000 0.988 0.012
C49.2 Connective and soft tissue of lower limb, including hip
0.000 0.988 0.012
H52.2 Astigmatism
0.012 0.988 0.000
C67.6 Ureteric orifice
0.000 0.988 0.012
M80.4 Drug-induced osteoporosis with pathological fracture
0.012 0.988 0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture
0.012 0.988 0.000
M80.2 Osteoporosis of disuse with pathological fracture
0.012 0.988 0.000
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)
0.012 0.988 0.000
H30-H36 Disorders of choroid and retina
0.012 0.988 0.000
C45.0 Mesothelioma of pleura
0.000 0.988 0.012
M80.8 Other osteoporosis with pathological fracture
0.012 0.988 0.000
H00 Hordeolum and chalazion
0.012 0.988 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.011 0.988 0.000
C45 Mesothelioma
0.000 0.988 0.011
C67.1 Dome of bladder
0.000 0.989 0.011
H52.6 Other disorders of refraction
0.011 0.989 0.000
H52.5 Disorders of accommodation
0.011 0.989 0.000
C49.9 Connective and soft tissue, unspecified
0.000 0.989 0.011
C49.6 Connective and soft tissue of trunk, unspecified
0.000 0.989 0.011
C49.5 Connective and soft tissue of pelvis
0.000 0.989 0.011
C49.1 Connective and soft tissue of upper limb, including shoulder
0.000 0.989 0.011
H52.3 Anisometropia and aniseikonia
0.010 0.989 0.000
C67.3 Anterior wall of bladder
0.000 0.990 0.010
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.000 0.990 0.010
H54.4 Blindness, one eye
0.010 0.990 0.000
C45.9 Mesothelioma, unspecified
0.000 0.990 0.010
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)
0.010 0.990 0.000
M80.58 Idiopathic osteoporosis with pathological fracture (Other)
0.010 0.990 0.000
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)
0.010 0.990 0.000
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)
0.010 0.990 0.000
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)
0.010 0.990 0.000
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)
0.010 0.990 0.000
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)
0.010 0.990 0.000
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)
0.010 0.990 0.000
C49.8 Overlapping lesion of connective and soft tissue
0.000 0.990 0.010
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)
0.010 0.990 0.000
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)
0.010 0.990 0.000
C67.7 Urachus
0.000 0.990 0.010
H52.7 Disorder of refraction, unspecified
0.010 0.990 0.000
M80.81 Other osteoporosis with pathological fracture (Shoulder region)
0.009 0.990 0.000
H52.4 Presbyopia
0.009 0.990 0.000
I77.1 Stricture of artery
0.000 0.991 0.009
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)
0.009 0.991 0.000
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)
0.009 0.991 0.000
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)
0.009 0.991 0.000
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)
0.009 0.991 0.000
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)
0.009 0.991 0.000
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)
0.009 0.991 0.000
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)
0.009 0.991 0.000
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)
0.009 0.991 0.000
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)
0.009 0.991 0.000
C67.8 Overlapping lesion of bladder
0.000 0.991 0.009
H30 Chorioretinal inflammation
0.009 0.991 0.000
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)
0.009 0.991 0.000
M80.28 Osteoporosis of disuse with pathological fracture (Other)
0.009 0.991 0.000
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)
0.009 0.991 0.000
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)
0.009 0.991 0.000
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)
0.009 0.991 0.000
M80.24 Osteoporosis of disuse with pathological fracture (Hand)
0.009 0.991 0.000
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)
0.009 0.991 0.000
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)
0.009 0.991 0.000
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)
0.009 0.991 0.000
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)
0.009 0.991 0.000
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)
0.009 0.991 0.000
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)
0.009 0.991 0.000
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)
0.009 0.991 0.000
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)
0.009 0.991 0.000
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)
0.009 0.991 0.000
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)
0.009 0.991 0.000
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)
0.009 0.991 0.000
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)
0.009 0.991 0.000
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)
0.009 0.991 0.000
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)
0.009 0.991 0.000
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)
0.009 0.991 0.000
M80.48 Drug-induced osteoporosis with pathological fracture (Other)
0.009 0.991 0.000
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)
0.009 0.991 0.000
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)
0.009 0.991 0.000
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)
0.009 0.991 0.000
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)
0.009 0.991 0.000
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)
0.009 0.991 0.000
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)
0.009 0.991 0.000
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)
0.009 0.991 0.000
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)
0.009 0.991 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.009 0.991 0.000
M80.89 Other osteoporosis with pathological fracture (Site unspecified)
0.009 0.991 0.000
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)
0.009 0.991 0.000
M80.86 Other osteoporosis with pathological fracture (Lower leg)
0.009 0.991 0.000
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)
0.009 0.991 0.000
M80.84 Other osteoporosis with pathological fracture (Hand)
0.009 0.991 0.000
M80.83 Other osteoporosis with pathological fracture (Forearm)
0.009 0.991 0.000
M80.82 Other osteoporosis with pathological fracture (Upper arm)
0.009 0.991 0.000
M80.80 Other osteoporosis with pathological fracture (Multiple sites)
0.009 0.991 0.000
H31 Other disorders of choroid
0.009 0.991 0.000
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)
0.008 0.991 0.000
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)
0.008 0.991 0.000
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)
0.008 0.991 0.000
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)
0.008 0.991 0.000
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)
0.008 0.991 0.000
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)
0.008 0.991 0.000
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)
0.008 0.991 0.000
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)
0.008 0.991 0.000
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)
0.008 0.991 0.000
C45.7 Mesothelioma of other sites
0.000 0.991 0.008
C49.4 Connective and soft tissue of abdomen
0.000 0.991 0.008
C45.2 Mesothelioma of pericardium
0.000 0.991 0.008
C45.1 Mesothelioma of peritoneum
0.000 0.991 0.008
H40 Glaucoma
0.008 0.992 0.000
C67.0 Trigone of bladder
0.000 0.992 0.008
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)
0.008 0.992 0.000
H00.0 Hordeolum and other deep inflammation of eyelid
0.008 0.992 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.000 0.992 0.008
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.000 0.992 0.008
C46 Kaposi's sarcoma
0.000 0.992 0.008
H40.5 Glaucoma secondary to other eye disorders
0.008 0.992 0.000
M80.88 Other osteoporosis with pathological fracture (Other)
0.007 0.992 0.000
H01.8 Other specified inflammation of eyelid
0.007 0.992 0.000
H30.2 Posterior cyclitis
0.007 0.993 0.000
H31.1 Choroidal degeneration
0.007 0.993 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.000 0.993 0.007
C66 Malignant neoplasm of ureter
0.000 0.993 0.007
M80-M85 Disorders of bone density and structure
0.007 0.993 0.000
H30.8 Other chorioretinal inflammations
0.007 0.993 0.000
H30.1 Disseminated chorioretinal inflammation
0.007 0.993 0.000
H30.0 Focal chorioretinal inflammation
0.007 0.993 0.000
C64-C68 Malignant neoplasms of urinary tract
0.000 0.993 0.007
H31.8 Other specified disorders of choroid
0.007 0.993 0.000
H40.3 Glaucoma secondary to eye trauma
0.007 0.993 0.000
H31.3 Choroidal haemorrhage and rupture
0.006 0.993 0.000
H32.8 Other chorioretinal disorders in diseases classified elsewhere
0.006 0.993 0.000
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere
0.006 0.993 0.000
H31.4 Choroidal detachment
0.006 0.993 0.000
H31.2 Hereditary choroidal dystrophy
0.006 0.993 0.000
C67.2 Lateral wall of bladder
0.000 0.994 0.006
H40.6 Glaucoma secondary to drugs
0.006 0.994 0.000
H30.9 Chorioretinal inflammation, unspecified
0.006 0.994 0.000
H34 Retinal vascular occlusions
0.006 0.994 0.000
M83 Adult osteomalacia
0.006 0.994 0.000
H40.8 Other glaucoma
0.006 0.994 0.000
H40.1 Primary open-angle glaucoma
0.006 0.994 0.000
C46.9 Kaposi's sarcoma, unspecified
0.000 0.994 0.006
C46.8 Kaposi's sarcoma of multiple organs
0.000 0.994 0.006
C46.7 Kaposi's sarcoma of other sites
0.000 0.994 0.006
C46.3 Kaposi's sarcoma of lymph nodes
0.000 0.994 0.006
C46.2 Kaposi's sarcoma of palate
0.000 0.994 0.006
C46.1 Kaposi's sarcoma of soft tissue
0.000 0.994 0.006
C46.0 Kaposi's sarcoma of skin
0.000 0.994 0.006
C47.9 Peripheral nerves and autonomic nervous system, unspecified
0.000 0.994 0.006
C47.8 Overlapping lesion of peripheral nerves and autonomic nervous system
0.000 0.994 0.006
C47.6 Peripheral nerves of trunk, unspecified
0.000 0.994 0.006
C47.5 Peripheral nerves of pelvis
0.000 0.994 0.006
C47.4 Peripheral nerves of abdomen
0.000 0.994 0.006
C47.3 Peripheral nerves of thorax
0.000 0.994 0.006
C47.2 Peripheral nerves of lower limb, including hip
0.000 0.994 0.006
C47.1 Peripheral nerves of upper limb, including shoulder
0.000 0.994 0.006
C47.0 Peripheral nerves of head, face and neck
0.000 0.994 0.006
H31.0 Chorioretinal scars
0.006 0.994 0.000
H31.9 Disorder of choroid, unspecified
0.005 0.994 0.000
M85 Other disorders of bone density and structure
0.005 0.995 0.000
M84 Disorders of continuity of bone
0.005 0.995 0.000
H40.4 Glaucoma secondary to eye inflammation
0.005 0.995 0.000
C65 Malignant neoplasm of renal pelvis
0.000 0.995 0.005
M82 Osteoporosis in diseases classified elsewhere
0.005 0.995 0.000
H36 Retinal disorders in diseases classified elsewhere
0.005 0.995 0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)
0.005 0.995 0.000
M13.00 Polyarthritis, unspecified (Multiple sites)
0.005 0.995 0.000
M83.1 Senile osteomalacia
0.005 0.995 0.000
M84.2 Delayed union of fracture
0.005 0.995 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.000 0.995 0.004
Z57.5 Occupational exposure to toxic agents in other industries
0.000 0.995 0.005
M83.8 Other adult osteomalacia
0.005 0.995 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.005 0.995 0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)
0.005 0.995 0.000
H52.1 Myopia
0.005 0.995 0.000
M85.2 Hyperostosis of skull
0.005 0.995 0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)
0.005 0.995 0.000
N93.8 Other specified abnormal uterine and vaginal bleeding
0.000 0.995 0.005
K31.9 Disease of stomach and duodenum, unspecified
0.000 0.995 0.005
M85.4 Solitary bone cyst
0.005 0.995 0.000
J11.1 Influenza with other respiratory manifestations, virus not identified
0.000 0.995 0.005
G83 Other paralytic syndromes
0.000 0.995 0.005
N85.9 Noninflammatory disorder of uterus, unspecified
0.000 0.995 0.005
G83.2 Monoplegia of upper limb
0.000 0.995 0.005
H34.0 Transient retinal artery occlusion
0.004 0.995 0.000
M84.25 Delayed union of fracture (Pelvic region and thigh)
0.004 0.995 0.000
H34.1 Central retinal artery occlusion
0.004 0.995 0.000
Z52.4 Kidney donor
0.000 0.995 0.005
M83.9 Adult osteomalacia, unspecified
0.004 0.995 0.000
M83.5 Other drug-induced osteomalacia in adults
0.004 0.995 0.000
M83.4 Aluminum bone disease
0.004 0.995 0.000
M83.2 Adult osteomalacia due to malabsorption
0.004 0.995 0.000
M83.0 Puerperal osteomalacia
0.004 0.995 0.000
M83.12 Senile osteomalacia (Upper arm)
0.004 0.996 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.000 0.996 0.004
M85.0 Fibrous dysplasia (monostotic)
0.004 0.996 0.000
M85.9 Disorder of bone density and structure, unspecified
0.004 0.996 0.000
M84.4 Pathological fracture, not elsewhere classified
0.004 0.996 0.000
M84.3 Stress fracture, not elsewhere classified
0.004 0.996 0.000
C73 Malignant neoplasm of thyroid gland
0.004 0.996 0.000
M83.3 Adult osteomalacia due to malnutrition
0.004 0.996 0.000
M85.22 Hyperostosis of skull-Upper arm
0.004 0.996 0.000
M85.5 Aneurysmal bone cyst
0.004 0.996 0.000
M85.3 Osteitis condensans
0.004 0.996 0.000
M85.1 Skeletal fluorosis
0.004 0.996 0.000
C48.0 Retroperitoneum
0.000 0.996 0.004
M84.9 Disorder of continuity of bone, unspecified
0.004 0.996 0.000
M83.80 Other adult osteomalacia (Multiple sites)
0.004 0.996 0.000
H34.9 Retinal vascular occlusion, unspecified
0.004 0.996 0.000
H52.0 Hypermetropia
0.004 0.996 0.000
M82.8 Osteoporosis in other diseases classified elsewhere
0.004 0.996 0.000
M82.0 Osteoporosis in multiple myelomatosis
0.004 0.996 0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm
0.004 0.996 0.000
M84.26 Delayed union of fracture (Lower leg)
0.004 0.996 0.000
M82.1 Osteoporosis in endocrine disorders
0.004 0.996 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.004 0.996 0.000
M85.46 Solitary bone cyst (Lower leg)
0.004 0.996 0.000
R52.1 Chronic intractable pain
0.000 0.996 0.004
Z52 Donors of organs and tissues
0.000 0.996 0.004
M83.19 Senile osteomalacia (Site unspecified)
0.004 0.996 0.000
M83.18 Senile osteomalacia (Other)
0.004 0.996 0.000
M83.17 Senile osteomalacia (Ankle and foot)
0.004 0.996 0.000
M83.16 Senile osteomalacia (Lower leg)
0.004 0.996 0.000
M83.15 Senile osteomalacia (Pelvic region and thigh)
0.004 0.996 0.000
M83.14 Senile osteomalacia (Hand)
0.004 0.996 0.000
M83.13 Senile osteomalacia (Forearm)
0.004 0.996 0.000
M83.11 Senile osteomalacia (Shoulder region)
0.004 0.996 0.000
M83.10 Senile osteomalacia (Multiple sites)
0.004 0.996 0.000
M84.29 Delayed union of fracture (Site unspecified)
0.004 0.996 0.000
M84.28 Delayed union of fracture (Other)
0.004 0.996 0.000
M84.27 Delayed union of fracture (Ankle and foot)
0.004 0.996 0.000
M84.24 Delayed union of fracture (Hand)
0.004 0.996 0.000
M84.23 Delayed union of fracture (Forearm)
0.004 0.996 0.000
M84.22 Delayed union of fracture (Upper arm)
0.004 0.996 0.000
M84.21 Delayed union of fracture (Shoulder region)
0.004 0.996 0.000
M84.20 Delayed union of fracture (Multiple sites)
0.004 0.996 0.000
M85.45 Solitary bone cyst (Pelvic region and thigh)
0.004 0.996 0.000
C48.8 Overlapping lesion of retroperitoneum and peritoneum
0.000 0.996 0.003
H34.2 Other retinal artery occlusions
0.004 0.996 0.000
G83.9 Paralytic syndrome, unspecified
0.000 0.996 0.004
M85.20 Hyperostosis of skull-Mult sites
0.004 0.996 0.000
C67.9 Bladder, unspecified
0.000 0.996 0.004
Z52.8 Donor of other organs and tissues
0.000 0.996 0.004
Z52.3 Bone marrow donor
0.000 0.996 0.004
M83.89 Other adult osteomalacia (Site unspecified)
0.004 0.996 0.000
M83.88 Other adult osteomalacia (Other)
0.004 0.996 0.000
M83.87 Other adult osteomalacia (Ankle and foot)
0.004 0.996 0.000
M83.86 Other adult osteomalacia (Lower leg)
0.004 0.996 0.000
M83.85 Other adult osteomalacia (Pelvic region and thigh)
0.004 0.996 0.000
M83.84 Other adult osteomalacia (Hand)
0.004 0.996 0.000
M83.83 Other adult osteomalacia (Forearm)
0.004 0.996 0.000
M83.82 Other adult osteomalacia (Upper arm)
0.004 0.996 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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