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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7275212
log Bayes Factor = 2.94756
Chromosome 21   position 39,852,551  (GRCh37) Explore rs7275212 on Ensembl!
Variant rs7275212 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
0.999 0.001 0.000
Chapter VII Diseases of the eye and adnexa
0.997 0.003 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.996 0.004 0.000
Chapter IX Diseases of the circulatory system
0.995 0.005 0.000
H40-H42 Glaucoma
0.986 0.014 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.981 0.019 0.000
I20-I25 Ischaemic heart diseases
0.979 0.021 0.000
H40 Glaucoma
0.978 0.022 0.000
S00-S09 Injuries to the head
0.976 0.024 0.000
Chapter V Mental and behavioural disorders
0.976 0.024 0.000
Chapter XXI Factors influencing health status and contact with health services
0.973 0.027 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.967 0.033 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.962 0.038 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.956 0.044 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.954 0.046 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.952 0.048 0.000
Z92 Personal history of medical treatment
0.950 0.050 0.000
F10.1 Harmful use
0.941 0.059 0.000
Z93 Artificial opening status
0.941 0.059 0.000
S02 Fracture of skull and facial bones
0.929 0.071 0.000
H53-H54 Visual disturbances and blindness
0.928 0.072 0.000
H40.9 Glaucoma, unspecified
0.919 0.081 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.916 0.084 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.912 0.088 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.911 0.089 0.000
I25 Chronic ischaemic heart disease
0.906 0.094 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.904 0.096 0.000
Z95.1 Presence of aortocoronary bypass graft
0.902 0.098 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.898 0.102 0.000
Z93.3 Colostomy status
0.891 0.109 0.000
H40.1 Primary open-angle glaucoma
0.890 0.110 0.000
H40.2 Primary angle-closure glaucoma
0.885 0.115 0.000
I22 Subsequent myocardial infarction
0.884 0.116 0.000
L60-L75 Disorders of skin appendages
0.875 0.125 0.000
I60-I69 Cerebrovascular diseases
0.869 0.131 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.863 0.137 0.000
S06 Intracranial injury
0.859 0.141 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.850 0.150 0.000
I21 Acute myocardial infarction
0.849 0.151 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.848 0.152 0.000
H02 Other disorders of eyelid
0.846 0.154 0.000
F10.3 Withdrawal state
0.844 0.156 0.000
Z93.2 Ileostomy status
0.831 0.169 0.000
H54 Blindness and low vision
0.827 0.173 0.000
I05-I09 Chronic rheumatic heart diseases
0.826 0.174 0.000
I24 Other acute ischaemic heart diseases
0.823 0.177 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.822 0.178 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.820 0.180 0.000
Z92.3 Personal history of irradiation
0.819 0.180 0.000
S01 Open wound of head
0.818 0.182 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.817 0.183 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.817 0.183 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.813 0.187 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.806 0.194 0.000
F10.2 Dependence syndrome
0.806 0.194 0.000
S60-S69 Injuries to the wrist and hand
0.804 0.196 0.000
H53 Visual disturbances
0.801 0.199 0.000
I95 Hypotension
0.799 0.201 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.790 0.210 0.000
L03 Cellulitis
0.789 0.211 0.000
S02.4 Fracture of malar and maxillary bones
0.788 0.212 0.000
S05 Injury of eye and orbit
0.786 0.214 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.786 0.214 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.783 0.217 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.782 0.218 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.777 0.223 0.000
Chapter XI Diseases of the digestive system
0.773 0.227 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.772 0.228 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.765 0.235 0.000
S02.8 Fractures of other skull and facial bones
0.765 0.235 0.000
S40-S49 Injuries to the shoulder and upper arm
0.764 0.236 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.761 0.239 0.000
Z95.3 Presence of xenogenic heart valve
0.760 0.240 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.760 0.240 0.000
S50-S59 Injuries to the elbow and forearm
0.759 0.240 0.000
S02.3 Fracture of orbital floor
0.757 0.243 0.000
I73 Other peripheral vascular diseases
0.757 0.243 0.000
K90-K93 Other diseases of the digestive system
0.756 0.244 0.000
H54.7 Unspecified visual loss
0.754 0.246 0.000
H02.8 Other specified disorders of eyelid
0.754 0.246 0.000
I25.1 Atherosclerotic heart disease
0.754 0.246 0.000
I77 Other disorders of arteries and arterioles
0.751 0.249 0.000
T66-T78 Other and unspecified effects of external causes
0.751 0.249 0.000
L40-L45 Papulosquamous disorders
0.747 0.253 0.000
I21.9 Acute myocardial infarction, unspecified
0.746 0.254 0.000
S02.1 Fracture of base of skull
0.744 0.256 0.000
H10-H13 Disorders of conjunctiva
0.742 0.258 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.741 0.259 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.741 0.259 0.000
L20-L30 Dermatitis and eczema
0.740 0.260 0.000
I63 Cerebral infarction
0.736 0.264 0.000
H40.0 Glaucoma suspect
0.733 0.267 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.731 0.269 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.725 0.275 0.000
Chapter XXII Codes for special purposes
0.725 0.275 0.000
L05 Pilonidal cyst
0.724 0.276 0.000
Z93.1 Gastrostomy status
0.724 0.276 0.000
S20-S29 Injuries to the thorax
0.719 0.281 0.000
Z95.2 Presence of prosthetic heart valve
0.719 0.281 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.718 0.281 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.716 0.284 0.000
H55-H59 Other disorders of eye and adnexa
0.715 0.285 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.715 0.285 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.715 0.285 0.000
H30-H36 Disorders of choroid and retina
0.714 0.286 0.000
T79-T79 Certain early complications of trauma
0.714 0.286 0.000
T33-T35 Frostbite
0.714 0.286 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.714 0.286 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.714 0.286 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.714 0.286 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.714 0.286 0.000
T00-T07 Injuries involving multiple body regions
0.714 0.286 0.000
S10-S19 Injuries to the neck
0.714 0.286 0.000
I00-I02 Acute rheumatic fever
0.713 0.286 0.000
S90-S99 Injuries to the ankle and foot
0.713 0.287 0.000
S02.2 Fracture of nasal bones
0.710 0.290 0.000
H04 Disorders of lachrymal system
0.710 0.290 0.000
I10-I15 Hypertensive diseases
0.709 0.291 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.708 0.292 0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.708 0.292 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.708 0.292 0.000
H42 Glaucoma in diseases classified elsewhere
0.707 0.293 0.000
I78 Diseases of capillaries
0.706 0.294 0.000
I72 Other aneurysm
0.706 0.294 0.000
I08 Multiple valve diseases
0.705 0.295 0.000
I95.1 Orthostatic hypotension
0.704 0.296 0.000
L10-L14 Bullous disorders
0.703 0.296 0.000
S80-S89 Injuries to the knee and lower leg
0.702 0.297 0.000
I23 Certain current complications following acute myocardial infarction
0.702 0.298 0.000
K92 Other diseases of digestive system
0.702 0.298 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.702 0.298 0.000
H02.3 Blepharochalasis
0.702 0.298 0.000
H40.8 Other glaucoma
0.701 0.298 0.000
H40.6 Glaucoma secondary to drugs
0.701 0.298 0.000
H40.5 Glaucoma secondary to other eye disorders
0.701 0.298 0.000
H40.4 Glaucoma secondary to eye inflammation
0.701 0.298 0.000
H40.3 Glaucoma secondary to eye trauma
0.701 0.298 0.000
S08 Traumatic amputation of part of head
0.700 0.300 0.000
S07 Crushing injury of head
0.700 0.300 0.000
S04 Injury of cranial nerves
0.700 0.300 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.700 0.300 0.000
F99-F99 Unspecified mental disorder
0.699 0.300 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.699 0.300 0.000
F80-F89 Disorders of psychological development
0.699 0.300 0.000
F70-F79 Mental retardation
0.699 0.300 0.000
F60-F69 Disorders of adult personality and behaviour
0.699 0.300 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.699 0.300 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.697 0.303 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.697 0.303 0.000
Z97 Presence of other devices
0.694 0.306 0.000
Z89 Acquired absence of limb
0.694 0.306 0.000
Z84 Family history of other conditions
0.694 0.306 0.000
Z81 Family history of mental and behavioural disorders
0.694 0.306 0.000
Chapter XX External causes of morbidity and mortality
0.693 0.307 0.000
I60 Subarachnoid haemorrhage
0.693 0.307 0.000
S06.3 Focal brain injury
0.691 0.309 0.000
F30-F39 Mood [affective] disorders
0.690 0.310 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.690 0.310 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.690 0.310 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.690 0.310 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.690 0.310 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.690 0.310 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.690 0.310 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.690 0.310 0.000
F11 Mental and behavioural disorders due to use of opioids
0.690 0.310 0.000
H02.5 Other disorders affecting eyelid function
0.689 0.311 0.000
I70 Atherosclerosis
0.688 0.311 0.000
S02.40 Fracture of malar and maxillary bones (closed)
0.687 0.313 0.000
H53.1 Subjective visual disturbances
0.686 0.314 0.000
F10.9 Unspecified mental and behavioural disorder
0.685 0.315 0.000
F10.8 Other mental and behavioural disorders
0.685 0.315 0.000
F10.7 Residual and late-onset psychotic disorder
0.685 0.315 0.000
F10.6 Amnesic syndrome
0.685 0.315 0.000
F10.5 Psychotic disorder
0.685 0.315 0.000
F10.4 Withdrawal state with delirium
0.685 0.315 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.684 0.316 0.000
L73 Other follicular disorders
0.683 0.317 0.000
L04 Acute lymphadenitis
0.682 0.317 0.000
L01 Impetigo
0.682 0.317 0.000
L00 Staphylococcal scalded skin syndrome
0.682 0.317 0.000
Z92.9 Personal history of medical treatment, unspecified
0.681 0.319 0.000
Z92.8 Personal history of other medical treatment
0.681 0.319 0.000
Z92.5 Personal history of rehabilitation measures
0.681 0.319 0.000
Z92.0 Personal history of contraception
0.681 0.319 0.000
L72.0 Epidermal cyst
0.681 0.319 0.000
L50-L54 Urticaria and erythema
0.678 0.322 0.000
I74 Arterial embolism and thrombosis
0.676 0.324 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.676 0.324 0.000
I24.8 Other forms of acute ischaemic heart disease
0.676 0.324 0.000
Z73 Problems related to life-management difficulty
0.675 0.325 0.000
Z93.9 Artificial opening status, unspecified
0.674 0.325 0.000
Z93.8 Other artificial opening status
0.674 0.325 0.000
Z93.5 Cystostomy status
0.674 0.325 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.674 0.325 0.000
Z93.0 Tracheostomy status
0.674 0.325 0.000
L03.0 Cellulitis of finger and toe
0.673 0.327 0.000
Z99.3 Dependence on wheelchair
0.671 0.329 0.000
Z74 Problems related to care-provider dependency
0.670 0.330 0.000
S01.8 Open wound of other parts of head
0.667 0.333 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.666 0.333 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.666 0.334 0.000
S02.7 Multiple fractures involving skull and facial bones
0.666 0.334 0.000
S02.6 Fracture of mandible
0.666 0.334 0.000
S02.5 Fracture of tooth
0.666 0.334 0.000
S02.0 Fracture of vault of skull
0.666 0.334 0.000
S06.5 Traumatic subdural haemorrhage
0.664 0.336 0.000
L60 Nail disorders
0.663 0.337 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.662 0.338 0.000
Z95.4 Presence of other heart-valve replacement
0.661 0.339 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.660 0.340 0.000
Z91.6 Personal history of other physical trauma
0.660 0.340 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.659 0.341 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.659 0.341 0.000
K92.1 Melaena
0.658 0.342 0.000
S70-S79 Injuries to the hip and thigh
0.657 0.343 0.000
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.657 0.343 0.000
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites
0.657 0.343 0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.657 0.343 0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.657 0.343 0.000
I21.4 Acute subendocardial myocardial infarction
0.655 0.345 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.655 0.345 0.000
K70-K77 Diseases of liver
0.654 0.346 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.653 0.347 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.653 0.347 0.000
Z75 Problems related to medical facilities and other health care
0.653 0.347 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.653 0.347 0.000
Chapter VIII Diseases of the ear and mastoid process
0.651 0.349 0.000
S05.1 Contusion of eyeball and orbital tissues
0.650 0.350 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.650 0.350 0.000
H50 Other strabismus
0.650 0.350 0.000
I25.6 Silent myocardial ischaemia
0.650 0.350 0.000
I25.5 Ischaemic cardiomyopathy
0.650 0.350 0.000
I25.4 Coronary artery aneurysm
0.650 0.350 0.000
I25.3 Aneurysm of heart
0.650 0.350 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.650 0.350 0.000
Z96 Presence of other functional implants
0.649 0.351 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.648 0.352 0.000
H05 Disorders of orbit
0.648 0.352 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.648 0.352 0.000
S02.80 Fractures of other skull and facial bones (closed)
0.647 0.353 0.000
Z94 Transplanted organ and tissue status
0.646 0.354 0.000
H53.8 Other visual disturbances
0.645 0.355 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.644 0.356 0.000
I99 Other and unspecified disorders of circulatory system
0.644 0.356 0.000
Z87 Personal history of other diseases and conditions
0.643 0.357 0.000
L08 Other local infections of skin and subcutaneous tissue
0.642 0.357 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.641 0.359 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.641 0.359 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.637 0.363 0.000
I77.1 Stricture of artery
0.637 0.363 0.000
L03.2 Cellulitis of face
0.635 0.365 0.000
T51 Toxic effect of alcohol
0.635 0.365 0.000
I73.9 Peripheral vascular disease, unspecified
0.634 0.366 0.000
I22.8 Subsequent myocardial infarction of other sites
0.633 0.366 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.633 0.366 0.000
F00 Dementia in Alzheimer's disease
0.633 0.366 0.000
S02.30 Fracture of orbital floor (closed)
0.633 0.367 0.000
Z98 Other postsurgical states
0.633 0.367 0.000
I69 Sequelae of cerebrovascular disease
0.633 0.367 0.000
I63.9 Cerebral infarction, unspecified
0.631 0.369 0.000
I95.9 Hypotension, unspecified
0.631 0.369 0.000
Z93.6 Other artificial openings of urinary tract status
0.630 0.370 0.000
H02.0 Entropion and trichiasis of eyelid
0.629 0.371 0.000
Z99.2 Dependence on renal dialysis
0.629 0.371 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.629 0.371 0.000
S00 Superficial injury of head
0.627 0.372 0.000
L75 Apocrine sweat disorders
0.627 0.373 0.000
L74 Eccrine sweat disorders
0.627 0.373 0.000
L71 Rosacea
0.627 0.373 0.000
L70 Acne
0.627 0.373 0.000
L68 Hypertrichosis
0.627 0.373 0.000
L67 Hair colour and hair shaft abnormalities
0.627 0.373 0.000
L66 Cicatricial alopecia [scarring hair loss]
0.627 0.373 0.000
L65 Other nonscarring hair loss
0.627 0.373 0.000
L64 Androgenic alopecia
0.627 0.373 0.000
L63 Alopecia areata
0.627 0.373 0.000
L62 Nail disorders in diseases classified elsewhere
0.627 0.373 0.000
T39.1 4-Aminophenol derivatives
0.627 0.373 0.000
I61 Intracerebral haemorrhage
0.623 0.377 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.623 0.377 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.623 0.377 0.000
I62 Other nontraumatic intracranial haemorrhage
0.623 0.377 0.000
K91.3 Postoperative intestinal obstruction
0.623 0.377 0.000
I67 Other cerebrovascular diseases
0.621 0.379 0.000
F03 Unspecified dementia
0.621 0.379 0.000
S01.1 Open wound of eyelid and periocular area
0.620 0.380 0.000
L03.9 Cellulitis, unspecified
0.619 0.381 0.000
H02.9 Disorder of eyelid, unspecified
0.619 0.381 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.619 0.381 0.000
Z99.8 Dependence on other enabling machines and devices
0.618 0.381 0.000
Q60-Q64 Congenital malformations of the urinary system
0.616 0.384 0.000
S06.9 Intracranial injury, unspecified
0.616 0.384 0.000
S06.8 Other intracranial injuries
0.616 0.384 0.000
S06.7 Intracranial injury with prolonged coma
0.616 0.384 0.000
S06.4 Epidural haemorrhage
0.616 0.384 0.000
S06.2 Diffuse brain injury
0.616 0.384 0.000
S06.1 Traumatic cerebral oedema
0.616 0.384 0.000
S06.0 Concussion
0.616 0.384 0.000
K04 Diseases of pulp and periapical tissues
0.616 0.384 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.615 0.385 0.000
H25-H28 Disorders of lens
0.615 0.385 0.000
I08.0 Disorders of both mitral and aortic valves
0.614 0.386 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.613 0.387 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.613 0.387 0.000
Chapter VI Diseases of the nervous system
0.612 0.388 0.000
S02.10 Fracture of base of skull (closed)
0.612 0.388 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.611 0.389 0.000
H01 Other inflammation of eyelid
0.610 0.390 0.000
Z76 Persons encountering health services in other circumstances
0.609 0.390 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.609 0.390 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.609 0.391 0.000
Q00-Q07 Congenital malformations of the nervous system
0.609 0.391 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.609 0.391 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.609 0.391 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.609 0.391 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.608 0.392 0.000
Z72 Problems related to lifestyle
0.608 0.392 0.000
H02.7 Other degenerative disorders of eyelid and periocular area
0.606 0.393 0.000
H02.6 Xanthelasma of eyelid
0.606 0.393 0.000
H02.2 Lagophthalmos
0.606 0.393 0.000
H02.1 Ectropion of eyelid
0.606 0.393 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.606 0.394 0.000
H43-H45 Disorders of vitreous body and globe
0.604 0.396 0.000
S01.5 Open wound of lip and oral cavity
0.604 0.396 0.000
L43 Lichen planus
0.602 0.398 0.000
S64 Injury of nerves at wrist and hand level
0.601 0.399 0.000
T92 Sequelae of injuries of upper limb
0.600 0.400 0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)
0.599 0.401 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.598 0.401 0.000
H53.9 Visual disturbance, unspecified
0.597 0.403 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.597 0.403 0.000
S42 Fracture of shoulder and upper arm
0.596 0.404 0.000
S01.0 Open wound of scalp
0.596 0.404 0.000
H54.9 Unspecified visual impairment (binocular)
0.593 0.407 0.000
H54.6 Unqualified visual loss, one eye
0.593 0.407 0.000
H54.5 Low vision, one eye
0.593 0.407 0.000
H54.4 Blindness, one eye
0.593 0.407 0.000
H54.3 Unqualified visual loss, both eyes
0.593 0.407 0.000
H54.2 Low vision, both eyes
0.593 0.407 0.000
H54.1 Blindness, one eye, low vision, other eye
0.593 0.407 0.000
H54.0 Blindness, both eyes
0.593 0.407 0.000
I09 Other rheumatic heart diseases
0.592 0.407 0.000
I07 Rheumatic tricuspid valve diseases
0.592 0.407 0.000
I06 Rheumatic aortic valve diseases
0.592 0.407 0.000
I05 Rheumatic mitral valve diseases
0.592 0.407 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.591 0.408 0.000
W00-W19 Falls
0.591 0.409 0.000
I24.1 Dressler's syndrome
0.590 0.410 0.000
S52 Fracture of forearm
0.590 0.410 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.590 0.410 0.000
T87 Complications peculiar to reattachment and amputation
0.589 0.411 0.000
T86 Failure and rejection of transplanted organs and tissues
0.589 0.411 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.589 0.411 0.000
I12 Hypertensive renal disease
0.589 0.411 0.000
Z99.9 Dependence on unspecified enabling machine and device
0.588 0.412 0.000
Z99.4 Dependence on artificial heart
0.588 0.412 0.000
Z99.1 Dependence on respirator
0.588 0.412 0.000
Z99.0 Dependence on aspirator
0.588 0.412 0.000
S62 Fracture at wrist and hand level
0.588 0.412 0.000
S01.9 Open wound of head, part unspecified
0.586 0.414 0.000
S01.7 Multiple open wounds of head
0.586 0.414 0.000
S01.4 Open wound of cheek and temporomandibular area
0.586 0.414 0.000
S01.3 Open wound of ear
0.586 0.414 0.000
S01.2 Open wound of nose
0.586 0.414 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.586 0.414 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.586 0.414 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.586 0.414 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.586 0.414 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.586 0.414 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.586 0.414 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.586 0.414 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.586 0.414 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.586 0.414 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.586 0.414 0.000
T36 Poisoning by systemic antibiotics
0.586 0.414 0.000
Z83 Family history of other specific disorders
0.584 0.415 0.000
H35 Other retinal disorders
0.583 0.417 0.000
I71 Aortic aneurysm and dissection
0.583 0.417 0.000
F10.0 Acute intoxication
0.582 0.418 0.000
S09 Other and unspecified injuries of head
0.581 0.419 0.000
Z80 Family history of malignant neoplasm
0.580 0.420 0.000
H53.2 Diplopia
0.579 0.421 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.578 0.422 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.578 0.422 0.000
F02 Dementia in other diseases classified elsewhere
0.578 0.422 0.000
F01 Vascular dementia
0.578 0.422 0.000
F09 Unspecified organic or symptomatic mental disorder
0.578 0.422 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.578 0.422 0.000
S81 Open wound of lower leg
0.578 0.422 0.000
Z13 Special screening examination for other diseases and disorders
0.578 0.422 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.577 0.422 0.000
H04.1 Other disorders of lachrymal gland
0.577 0.423 0.000
Z95.0 Presence of cardiac pacemaker
0.576 0.424 0.000
S69 Other and unspecified injuries of wrist and hand
0.576 0.424 0.000
S68 Traumatic amputation of wrist and hand
0.576 0.424 0.000
S67 Crushing injury of wrist and hand
0.576 0.424 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.576 0.424 0.000
S65 Injury of blood vessels at wrist and hand level
0.576 0.424 0.000
S60 Superficial injury of wrist and hand
0.576 0.424 0.000
T78 Adverse effects, not elsewhere classified
0.575 0.424 0.000
S61 Open wound of wrist and hand
0.575 0.425 0.000
L72.1 Trichilemmal cyst
0.575 0.425 0.000
H53.6 Night blindness
0.575 0.425 0.000
H53.5 Colour vision deficiencies
0.575 0.425 0.000
H53.3 Other disorders of binocular vision
0.575 0.425 0.000
I95.8 Other hypotension
0.573 0.427 0.000
I95.2 Hypotension due to drugs
0.573 0.427 0.000
I95.0 Idiopathic hypotension
0.573 0.427 0.000
I30-I52 Other forms of heart disease
0.572 0.428 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.572 0.428 0.000
S06.30 Focal brain injury (without open intracranial wound)
0.571 0.429 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.570 0.430 0.000
K14 Diseases of tongue
0.570 0.430 0.000
L03.3 Cellulitis of trunk
0.569 0.430 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.567 0.433 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.566 0.434 0.000
Q80-Q89 Other congenital malformations
0.566 0.434 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.566 0.434 0.000
Q50-Q56 Congenital malformations of genital organs
0.566 0.434 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.566 0.434 0.000
Q35-Q37 Cleft lip and cleft palate
0.566 0.434 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.566 0.434 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.566 0.434 0.000
L03.8 Cellulitis of other sites
0.566 0.434 0.000
K10 Other diseases of jaws
0.566 0.434 0.000
H53.4 Visual field defects
0.565 0.435 0.000
S02.41 Fracture of malar and maxillary bones (open)
0.565 0.435 0.000
S05.9 Injury of eye and orbit, part unspecified
0.564 0.436 0.000
S05.8 Other injuries of eye and orbit
0.564 0.436 0.000
S05.7 Avulsion of eye
0.564 0.436 0.000
S05.6 Penetrating wound of eyeball without foreign body
0.564 0.436 0.000
S05.5 Penetrating wound of eyeball with foreign body
0.564 0.436 0.000
S05.4 Penetrating wound of orbit with or without foreign body
0.564 0.436 0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue
0.564 0.436 0.000
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue
0.564 0.436 0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body
0.564 0.436 0.000
I73.0 Raynaud's syndrome
0.563 0.436 0.000
L82 Seborrhoeic keratosis
0.563 0.437 0.000
T65 Toxic effect of other and unspecified substances
0.563 0.437 0.000
T63 Toxic effect of contact with venomous animals
0.563 0.437 0.000
T62 Toxic effect of other noxious substances eaten as food
0.563 0.437 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.563 0.437 0.000
T60 Toxic effect of pesticides
0.563 0.437 0.000
T59 Toxic effect of other gases, fumes and vapours
0.563 0.437 0.000
T57 Toxic effect of other inorganic substances
0.563 0.437 0.000
T56 Toxic effect of metals
0.563 0.437 0.000
T54 Toxic effect of corrosive substances
0.563 0.437 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.563 0.437 0.000
T52 Toxic effect of organic solvents
0.563 0.437 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.563 0.437 0.000
T58 Toxic effect of carbon monoxide
0.563 0.437 0.000
T55 Toxic effect of soaps and detergents
0.563 0.437 0.000
K91.4 Colostomy and enterostomy malfunction
0.563 0.437 0.000
H00 Hordeolum and chalazion
0.562 0.437 0.000
K90 Intestinal malabsorption
0.562 0.438 0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.562 0.438 0.000
L05.0 Pilonidal cyst with abscess
0.561 0.439 0.000
H51 Other disorders of binocular movement
0.561 0.439 0.000
H49 Paralytic strabismus
0.561 0.439 0.000
L29 Pruritus
0.560 0.439 0.000
I78.1 Naevus, nonneoplastic
0.559 0.441 0.000
H11 Other disorders of conjunctiva
0.559 0.441 0.000
I72.4 Aneurysm of artery of lower extremity
0.558 0.441 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.558 0.441 0.000
S32 Fracture of lumbar spine and pelvis
0.558 0.442 0.000
Z88.2 Personal history of allergy to sulphonamides
0.558 0.442 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.556 0.444 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.554 0.446 0.000
S02.20 Fracture of nasal bones (closed)
0.554 0.446 0.000
L90 Atrophic disorders of skin
0.553 0.447 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.552 0.448 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.552 0.448 0.000
K07 Dentofacial anomalies [including malocclusion]
0.551 0.449 0.000
Z73.3 Stress, not elsewhere classified
0.550 0.450 0.000
Z13.9 Special screening examination, unspecified
0.549 0.450 0.000
T98 Sequelae of other and unspecified effects of external causes
0.548 0.451 0.000
T95 Sequelae of burns, corrosions and frostbite
0.548 0.451 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.548 0.451 0.000
T93 Sequelae of injuries of lower limb
0.548 0.451 0.000
T91 Sequelae of injuries of neck and trunk
0.548 0.451 0.000
T90 Sequelae of injuries of head
0.548 0.451 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.548 0.451 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.548 0.451 0.000
S02.81 Fractures of other skull and facial bones (open)
0.548 0.451 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.548 0.452 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.548 0.452 0.000
S48 Traumatic amputation of shoulder and upper arm
0.548 0.452 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.548 0.452 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.548 0.452 0.000
S44 Injury of nerves at shoulder and upper arm level
0.548 0.452 0.000
S41 Open wound of shoulder and upper arm
0.548 0.452 0.000
S40 Superficial injury of shoulder and upper arm
0.548 0.452 0.000
S47 Crushing injury of shoulder and upper arm
0.548 0.452 0.000
L81 Other disorders of pigmentation
0.548 0.452 0.000
Z72.1 Alcohol use
0.547 0.453 0.000
L73.9 Follicular disorder, unspecified
0.545 0.455 0.000
L72.8 Other follicular cysts of skin and subcutaneous tissue
0.545 0.455 0.000
L72.2 Steatocystoma multiplex
0.545 0.455 0.000
S59 Other and unspecified injuries of forearm
0.545 0.455 0.000
S58 Traumatic amputation of forearm
0.545 0.455 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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