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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs72753808
log Bayes Factor = 20.4495
Chromosome 1   position 204,517,487  (GRCh37) Explore rs72753808 on Ensembl!
Variant rs72753808 is part of Cluster X0150

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
0.999 0.001 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
R50-R69 General symptoms and signs
0.997 0.003 0.000
Chapter VI Diseases of the nervous system
0.996 0.004 0.000
M70-M79 Other soft tissue disorders
0.991 0.009 0.000
I30-I52 Other forms of heart disease
0.989 0.011 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.985 0.015 0.000
J09-J18 Influenza and pneumonia
0.985 0.015 0.000
I25.1 Atherosclerotic heart disease
0.983 0.017 0.000
I60-I69 Cerebrovascular diseases
0.981 0.019 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.981 0.019 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.977 0.023 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.976 0.024 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.973 0.027 0.000
R51 Headache
0.969 0.031 0.000
I21 Acute myocardial infarction
0.968 0.032 0.000
J18 Pneumonia, organism unspecified
0.966 0.034 0.000
G81 Hemiplegia
0.962 0.038 0.000
M75 Shoulder lesions
0.962 0.038 0.000
J30-J39 Other diseases of upper respiratory tract
0.958 0.042 0.000
J18.1 Lobar pneumonia, unspecified
0.956 0.044 0.000
G81.9 Hemiplegia, unspecified
0.953 0.047 0.000
J40-J47 Chronic lower respiratory diseases
0.952 0.048 0.000
Chapter I Certain infectious and parasitic diseases
0.951 0.049 0.000
M05-M14 Inflammatory polyarthropathies
0.946 0.054 0.000
I35 Nonrheumatic aortic valve disorders
0.946 0.054 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.944 0.056 0.000
R47-R49 Symptoms and signs involving speech and voice
0.934 0.066 0.000
I69 Sequelae of cerebrovascular disease
0.933 0.067 0.000
M45-M49 Spondylopathies
0.931 0.069 0.000
J44 Other chronic obstructive pulmonary disease
0.927 0.073 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.923 0.077 0.000
I45 Other conduction disorders
0.922 0.078 0.000
R63 Symptoms and signs concerning food and fluid intake
0.921 0.079 0.000
I73 Other peripheral vascular diseases
0.919 0.081 0.000
R00 Abnormalities of heart beat
0.916 0.084 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.911 0.089 0.000
I21.9 Acute myocardial infarction, unspecified
0.910 0.090 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.903 0.097 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.897 0.103 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.896 0.104 0.000
Chapter XXI Factors influencing health status and contact with health services
0.893 0.107 0.000
R00.0 Tachycardia, unspecified
0.891 0.109 0.000
R63.4 Abnormal weight loss
0.891 0.109 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.891 0.109 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.890 0.110 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.888 0.112 0.000
I34 Nonrheumatic mitral valve disorders
0.884 0.116 0.000
I84 Haemorrhoids
0.883 0.117 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.881 0.119 0.000
R15 Faecal incontinence
0.879 0.121 0.000
J43 Emphysema
0.878 0.122 0.000
I05-I09 Chronic rheumatic heart diseases
0.875 0.125 0.000
R19.0 Intra-abdominal and pelvic swelling, mass and lump
0.874 0.126 0.000
I45.1 Other and unspecified right bundle-branch block
0.874 0.126 0.000
R17 Unspecified jaundice
0.873 0.127 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.873 0.127 0.000
R06 Abnormalities of breathing
0.870 0.130 0.000
R50 Fever of unknown origin
0.869 0.131 0.000
Chapter XXII Codes for special purposes
0.869 0.131 0.000
R20 Disturbances of skin sensation
0.868 0.132 0.000
I35.0 Aortic (valve) stenosis
0.864 0.136 0.000
R47 Speech disturbances, not elsewhere classified
0.858 0.142 0.000
M47 Spondylosis
0.858 0.142 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.855 0.145 0.000
M20-M25 Other joint disorders
0.853 0.147 0.000
R14 Flatulence and related conditions
0.853 0.147 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.852 0.148 0.000
J32 Chronic sinusitis
0.850 0.150 0.000
I84.9 Unspecified haemorrhoids without complication
0.850 0.150 0.000
D50-D53 Nutritional anaemias
0.849 0.151 0.000
M06 Other rheumatoid arthritis
0.849 0.151 0.000
I71 Aortic aneurysm and dissection
0.848 0.152 0.000
M40-M43 Deforming dorsopathies
0.846 0.154 0.000
M15-M19 Arthrosis
0.845 0.155 0.000
R68 Other general symptoms and signs
0.843 0.157 0.000
M75.0 Adhesive capsulitis of shoulder
0.843 0.157 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.839 0.161 0.000
I73.9 Peripheral vascular disease, unspecified
0.839 0.161 0.000
M13 Other arthritis
0.838 0.162 0.000
M75.5 Bursitis of shoulder
0.837 0.163 0.000
B35-B49 Mycoses
0.836 0.164 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.836 0.164 0.000
A30-A49 Other bacterial diseases
0.835 0.165 0.000
E20-E35 Disorders of other endocrine glands
0.835 0.165 0.000
I33 Acute and subacute endocarditis
0.832 0.168 0.000
I38 Endocarditis, valve unspecified
0.831 0.169 0.000
L60-L75 Disorders of skin appendages
0.831 0.169 0.000
D50 Iron deficiency anaemia
0.829 0.171 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.828 0.172 0.000
J43.9 Emphysema, unspecified
0.826 0.174 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.826 0.174 0.000
R18 Ascites
0.824 0.176 0.000
R57 Shock, not elsewhere classified
0.822 0.178 0.000
I35.1 Aortic (valve) insufficiency
0.821 0.179 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.821 0.179 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.819 0.181 0.000
M50-M54 Other dorsopathies
0.819 0.181 0.000
R07 Pain in throat and chest
0.817 0.183 0.000
G30-G32 Other degenerative diseases of the nervous system
0.816 0.184 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.814 0.186 0.000
I10-I15 Hypertensive diseases
0.813 0.187 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.812 0.188 0.000
B95-B98 Bacterial, viral and other infectious agents
0.811 0.189 0.000
R01 Cardiac murmurs and other cardiac sounds
0.807 0.193 0.000
Chapter VII Diseases of the eye and adnexa
0.806 0.194 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.804 0.196 0.000
G90-G99 Other disorders of the nervous system
0.804 0.196 0.000
I84.8 Unspecified haemorrhoids with other complications
0.798 0.202 0.000
R54 Senility
0.798 0.202 0.000
Chapter VIII Diseases of the ear and mastoid process
0.797 0.203 0.000
I65.2 Occlusion and stenosis of carotid artery
0.795 0.205 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.795 0.205 0.000
G20-G26 Extrapyramidal and movement disorders
0.793 0.207 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.791 0.209 0.000
R52 Pain, not elsewhere classified
0.788 0.212 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.788 0.212 0.000
I77 Other disorders of arteries and arterioles
0.786 0.214 0.000
I69.3 Sequelae of cerebral infarction
0.785 0.215 0.000
E65-E68 Obesity and other hyperalimentation
0.783 0.217 0.000
M47.9 Spondylosis, unspecified
0.783 0.217 0.000
R19.5 Other fecal abnormalities
0.782 0.218 0.000
M76 Enthesopathies of lower limb, excluding foot
0.781 0.219 0.000
M75.9 Shoulder lesion, unspecified
0.780 0.220 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.780 0.220 0.000
M06.9 Rheumatoid arthritis, unspecified
0.779 0.221 0.000
R56 Convulsions, not elsewhere classified
0.779 0.221 0.000
J35 Chronic diseases of tonsils and adenoids
0.775 0.224 0.000
I34.0 Mitral (valve) insufficiency
0.775 0.225 0.000
I73.0 Raynaud's syndrome
0.775 0.225 0.000
R47.0 Dysphasia and aphasia
0.773 0.227 0.000
I08 Multiple valve diseases
0.773 0.227 0.000
D50.8 Other iron deficiency anaemias
0.773 0.227 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.773 0.227 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.773 0.227 0.000
I25.3 Aneurysm of heart
0.772 0.228 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.772 0.228 0.000
M79.6 Pain in limb
0.772 0.228 0.000
M75.1 Rotator cuff syndrome
0.771 0.229 0.000
H30-H36 Disorders of choroid and retina
0.770 0.230 0.000
M46 Other inflammatory spondylopathies
0.770 0.230 0.000
I26 Pulmonary embolism
0.770 0.230 0.000
M79.8 Other specified soft tissue disorders
0.769 0.231 0.000
J32.9 Chronic sinusitis, unspecified
0.769 0.231 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.768 0.231 0.000
M25 Other joint disorders, not elsewhere classified
0.768 0.232 0.000
R49 Voice disturbances
0.767 0.233 0.000
J11 Influenza, virus not identified
0.766 0.234 0.000
I72 Other aneurysm
0.765 0.235 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.764 0.236 0.000
J10 Influenza due to identified influenza virus
0.762 0.238 0.000
R07.4 Chest pain, unspecified
0.761 0.239 0.000
M13.9 Arthritis, unspecified
0.760 0.240 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.760 0.240 0.000
I22 Subsequent myocardial infarction
0.759 0.241 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.759 0.241 0.000
H33 Retinal detachments and breaks
0.759 0.241 0.000
R73 Elevated blood glucose level
0.759 0.241 0.000
I60 Subarachnoid haemorrhage
0.757 0.243 0.000
I63 Cerebral infarction
0.757 0.243 0.000
S60-S69 Injuries to the wrist and hand
0.756 0.244 0.000
R50.9 Fever, unspecified
0.756 0.244 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.755 0.245 0.000
J60-J70 Lung diseases due to external agents
0.753 0.247 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.752 0.248 0.000
R06.8 Other and unspecified abnormalities of breathing
0.749 0.251 0.000
R61 Hyperhidrosis
0.749 0.251 0.000
J90-J94 Other diseases of pleura
0.749 0.251 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.748 0.252 0.000
H33.0 Retinal detachment with retinal break
0.748 0.252 0.000
M17 Gonarthrosis [arthrosis of knee]
0.748 0.252 0.000
R06.0 Dyspnoea
0.747 0.253 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.747 0.253 0.000
M77 Other enthesopathies
0.745 0.255 0.000
M43 Other deforming dorsopathies
0.744 0.256 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.744 0.256 0.000
Z04 Examination and observation for other reasons
0.744 0.256 0.000
I25.2 Old myocardial infarction
0.743 0.257 0.000
I78 Diseases of capillaries
0.743 0.257 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.742 0.258 0.000
R19.4 Change in bowel habit
0.742 0.258 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.742 0.258 0.000
R19.8 Other specified symptoms and signs involving the digestive system and abdomen
0.741 0.259 0.000
M91-M94 Chondropathies
0.740 0.260 0.000
B15-B19 Viral hepatitis
0.739 0.261 0.000
I51 Complications and ill-defined descriptions of heart disease
0.737 0.263 0.000
R79 Other abnormal findings of blood chemistry
0.736 0.264 0.000
I74 Arterial embolism and thrombosis
0.736 0.264 0.000
L20-L30 Dermatitis and eczema
0.735 0.265 0.000
T66-T78 Other and unspecified effects of external causes
0.735 0.265 0.000
Z09.0 Follow-up examination after surgery for other conditions
0.734 0.266 0.000
I62 Other nontraumatic intracranial haemorrhage
0.733 0.267 0.000
G40-G47 Episodic and paroxysmal disorders
0.733 0.267 0.000
R68.8 Other specified general symptoms and signs
0.732 0.268 0.000
R53 Malaise and fatigue
0.732 0.268 0.000
R00.1 Bradycardia, unspecified
0.731 0.269 0.000
I61 Intracerebral haemorrhage
0.730 0.270 0.000
I35.8 Other aortic valve disorders
0.729 0.271 0.000
M65-M68 Disorders of synovium and tendon
0.728 0.272 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.728 0.272 0.000
M75.4 Impingement syndrome of shoulder
0.727 0.273 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.727 0.273 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.727 0.273 0.000
M19 Other arthrosis
0.726 0.274 0.000
L72.1 Trichilemmal cyst
0.725 0.275 0.000
M79.66 Pain in limb (Lower leg)
0.725 0.275 0.000
R55 Syncope and collapse
0.724 0.276 0.000
J39 Other diseases of upper respiratory tract
0.724 0.276 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.723 0.277 0.000
M86-M90 Other osteopathies
0.722 0.278 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.720 0.280 0.000
I33.0 Acute and subacute infective endocarditis
0.720 0.280 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.716 0.283 0.000
I25.5 Ischaemic cardiomyopathy
0.716 0.283 0.000
I25.4 Coronary artery aneurysm
0.716 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.716 0.283 0.000
Z09.2 Follow-up examination after chemotherapy for other conditions
0.715 0.285 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.715 0.285 0.000
R62 Lack of expected normal physiological development
0.715 0.285 0.000
R64 Cachexia
0.715 0.285 0.000
R58 Haemorrhage, not elsewhere classified
0.715 0.285 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.714 0.286 0.000
I34.1 Mitral (valve) prolapse
0.713 0.287 0.000
J40 Bronchitis, not specified as acute or chronic
0.713 0.287 0.000
M71 Other bursopathies
0.713 0.287 0.000
J31.0 Chronic rhinitis
0.711 0.289 0.000
B25-B34 Other viral diseases
0.711 0.289 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.711 0.289 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.711 0.289 0.000
G70-G73 Diseases of myoneural junction and muscle
0.710 0.290 0.000
B35 Dermatophytosis
0.710 0.290 0.000
G50 Disorders of trigeminal nerve
0.709 0.291 0.000
I50 Heart failure
0.709 0.291 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.709 0.291 0.000
I52 Other heart disorders in diseases classified elsewhere
0.709 0.291 0.000
I48 Atrial fibrillation and flutter
0.709 0.291 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.709 0.291 0.000
I41 Myocarditis in diseases classified elsewhere
0.709 0.291 0.000
I40 Acute myocarditis
0.709 0.291 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.709 0.291 0.000
I37 Pulmonary valve disorders
0.709 0.291 0.000
I36 Nonrheumatic tricuspid valve disorders
0.709 0.291 0.000
I32 Pericarditis in diseases classified elsewhere
0.709 0.291 0.000
I30 Acute pericarditis
0.709 0.291 0.000
I67 Other cerebrovascular diseases
0.708 0.292 0.000
R06.2 Wheezing
0.708 0.292 0.000
E66 Obesity
0.707 0.293 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.707 0.293 0.000
J17 Pneumonia in diseases classified elsewhere
0.706 0.294 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.706 0.294 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.706 0.294 0.000
J12 Viral pneumonia, not elsewhere classified
0.706 0.294 0.000
J14 Pneumonia due to Haemophilus influenzae
0.706 0.294 0.000
J09 Influenza due to certain identified influenza virus
0.706 0.294 0.000
I95 Hypotension
0.705 0.295 0.000
H53-H54 Visual disturbances and blindness
0.705 0.295 0.000
M75.2 Bicipital tendinitis
0.704 0.296 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.703 0.297 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.703 0.297 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.703 0.297 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.703 0.297 0.000
G83 Other paralytic syndromes
0.703 0.297 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.702 0.298 0.000
R59 Enlarged lymph nodes
0.701 0.299 0.000
I24 Other acute ischaemic heart diseases
0.701 0.299 0.000
G82 Paraplegia and tetraplegia
0.700 0.300 0.000
G80 Infantile cerebral palsy
0.700 0.300 0.000
A41 Other septicaemia
0.700 0.300 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.699 0.301 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.698 0.302 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.697 0.303 0.000
R57.2 Septic shock
0.697 0.303 0.000
M11 Other crystal arthropathies
0.697 0.303 0.000
M79.1 Myalgia
0.697 0.303 0.000
M47.8 Other spondylosis
0.696 0.304 0.000
J38.3 Other diseases of vocal cords
0.695 0.304 0.000
R20.2 Paraesthesia of skin
0.694 0.306 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.694 0.306 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.694 0.306 0.000
M25.7 Osteophyte
0.694 0.306 0.000
I21.4 Acute subendocardial myocardial infarction
0.694 0.306 0.000
R74 Abnormal serum enzyme levels
0.694 0.306 0.000
J18.8 Other pneumonia, organism unspecified
0.693 0.307 0.000
J18.2 Hypostatic pneumonia, unspecified
0.693 0.307 0.000
J18.9 Pneumonia, unspecified
0.692 0.308 0.000
G81.1 Spastic hemiplegia
0.690 0.310 0.000
G81.0 Flaccid hemiplegia
0.690 0.310 0.000
M75.8 Other shoulder lesions
0.690 0.310 0.000
R01.1 Cardiac murmur, unspecified
0.688 0.312 0.000
R47.8 Other and unspecified speech disturbances
0.688 0.312 0.000
M21 Other acquired deformities of limbs
0.688 0.312 0.000
M75.3 Calcific tendinitis of shoulder
0.687 0.313 0.000
J37 Chronic laryngitis and laryngotracheitis
0.687 0.313 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.687 0.313 0.000
I84.5 External haemorrhoids without complication
0.686 0.314 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.685 0.315 0.000
H80-H83 Diseases of inner ear
0.683 0.317 0.000
J41 Simple and mucopurulent chronic bronchitis
0.682 0.318 0.000
M10 Gout
0.682 0.318 0.000
B37 Candidiasis
0.682 0.318 0.000
B99-B99 Other infectious diseases
0.682 0.318 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.682 0.318 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.682 0.318 0.000
B65-B83 Helminthiases
0.682 0.318 0.000
B50-B64 Protozoal diseases
0.682 0.318 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.682 0.318 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.682 0.318 0.000
A80-A89 Viral infections of the central nervous system
0.682 0.318 0.000
A75-A79 Rickettsioses
0.682 0.318 0.000
A70-A74 Other diseases caused by chlamydiae
0.682 0.318 0.000
A65-A69 Other spirochaetal diseases
0.682 0.318 0.000
A20-A28 Certain zoonotic bacterial diseases
0.682 0.318 0.000
A15-A19 Tuberculosis
0.682 0.318 0.000
R23 Other skin changes
0.681 0.319 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.681 0.319 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.681 0.319 0.000
M54 Dorsalgia
0.681 0.319 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.681 0.319 0.000
S70-S79 Injuries to the hip and thigh
0.680 0.320 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.680 0.320 0.000
J30 Vasomotor and allergic rhinitis
0.680 0.320 0.000
S80-S89 Injuries to the knee and lower leg
0.679 0.321 0.000
I42 Cardiomyopathy
0.679 0.321 0.000
M14 Arthropathies in other diseases classified elsewhere
0.678 0.322 0.000
M12 Other specific arthropathies
0.678 0.322 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.678 0.322 0.000
M08 Juvenile arthritis
0.678 0.322 0.000
M07 Psoriatic and enteropathic arthropathies
0.678 0.322 0.000
I35.9 Aortic valve disorder, unspecified
0.678 0.322 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.678 0.322 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.678 0.322 0.000
E40-E46 Malnutrition
0.677 0.323 0.000
R19.6 Halitosis
0.676 0.323 0.000
R19.3 Abdominal rigidity
0.676 0.323 0.000
R19.2 Visible peristalsis
0.676 0.323 0.000
R19.1 Abnormal bowel sounds
0.676 0.323 0.000
T90 Sequelae of injuries of head
0.676 0.324 0.000
Chapter XX External causes of morbidity and mortality
0.675 0.325 0.000
I46 Cardiac arrest
0.675 0.325 0.000
E23 Hypofunction and other disorders of pituitary gland
0.675 0.325 0.000
M50 Cervical disk disorders
0.673 0.327 0.000
J46 Status asthmaticus
0.672 0.328 0.000
R02 Gangrene, not elsewhere classified
0.672 0.328 0.000
M43.1 Spondylolisthesis
0.672 0.328 0.000
R50.0 Fever with chills
0.671 0.329 0.000
I70 Atherosclerosis
0.670 0.330 0.000
R26 Abnormalities of gait and mobility
0.670 0.330 0.000
R52.2 Other chronic pain
0.670 0.330 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.669 0.330 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.669 0.331 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.669 0.331 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.669 0.331 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.669 0.331 0.000
Z09.8 Follow-up examination after other treatment for other conditions
0.668 0.332 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.667 0.332 0.000
M49 Spondylopathies in diseases classified elsewhere
0.667 0.333 0.000
R09.1 Pleurisy
0.665 0.335 0.000
M80-M85 Disorders of bone density and structure
0.664 0.335 0.000
M48 Other spondylopathies
0.664 0.336 0.000
L60 Nail disorders
0.664 0.336 0.000
Chapter XI Diseases of the digestive system
0.663 0.337 0.000
M13.94 Arthritis, unspecified (Hand)
0.663 0.337 0.000
J32.8 Other chronic sinusitis
0.662 0.338 0.000
E22 Hyperfunction of pituitary gland
0.661 0.339 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.661 0.339 0.000
I45.9 Conduction disorder, unspecified
0.661 0.339 0.000
I45.8 Other specified conduction disorders
0.661 0.339 0.000
I45.6 Preexcitation syndrome
0.661 0.339 0.000
I45.5 Other specified heart block
0.661 0.339 0.000
I45.4 Nonspecific intraventricular block
0.661 0.339 0.000
I45.3 Trifascicular block
0.661 0.339 0.000
I45.2 Bifascicular block
0.661 0.339 0.000
I45.0 Right fascicular block
0.661 0.339 0.000
I12 Hypertensive renal disease
0.661 0.339 0.000
M34 Systemic sclerosis
0.660 0.339 0.000
R63.8 Other symptoms and signs concerning food and fluid intake
0.660 0.340 0.000
R63.6 Insufficient intake of food and water due to self neglect
0.660 0.340 0.000
R63.5 Abnormal weight gain
0.660 0.340 0.000
R63.3 Feeding difficulties and mismanagement
0.660 0.340 0.000
R63.2 Polyphagia
0.660 0.340 0.000
R63.1 Polydipsia
0.660 0.340 0.000
A40 Streptococcal septicaemia
0.660 0.340 0.000
G50.0 Trigeminal neuralgia
0.659 0.341 0.000
I73.8 Other specified peripheral vascular diseases
0.659 0.341 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.659 0.341 0.000
U80 Agent resistant to penicillin and related antibiotics
0.658 0.342 0.000
M05 Seropositive rheumatoid arthritis
0.658 0.342 0.000
R73.9 Hyperglycaemia, unspecified
0.658 0.342 0.000
E24 Cushing's syndrome
0.658 0.342 0.000
M35 Other systemic involvement of connective tissue
0.657 0.343 0.000
R21 Rash and other nonspecific skin eruption
0.657 0.343 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.656 0.344 0.000
I50.1 Left ventricular failure
0.655 0.345 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.654 0.346 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.654 0.346 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.654 0.346 0.000
Z29 Need for other prophylactic measures
0.654 0.346 0.000
G95 Other diseases of spinal cord
0.654 0.346 0.000
I88 Nonspecific lymphadenitis
0.653 0.347 0.000
I87 Other disorders of veins
0.653 0.347 0.000
I81 Portal vein thrombosis
0.653 0.347 0.000
Z04.8 Examination and observation for other specified reasons
0.653 0.347 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.653 0.347 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.652 0.348 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.651 0.349 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.651 0.349 0.000
I82 Other venous embolism and thrombosis
0.651 0.349 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.649 0.351 0.000
I77.1 Stricture of artery
0.649 0.351 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.648 0.352 0.000
R49.0 Dysphonia
0.648 0.352 0.000
M79.9 Soft tissue disorder, unspecified
0.647 0.352 0.000
M79.5 Residual foreign body in soft tissue
0.647 0.352 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.647 0.352 0.000
M79.3 Panniculitis, unspecified
0.647 0.352 0.000
M79.2 Neuralgia and neuritis, unspecified
0.647 0.352 0.000
E50-E64 Other nutritional deficiencies
0.647 0.353 0.000
J42 Unspecified chronic bronchitis
0.647 0.353 0.000
J36 Peritonsillar abscess
0.646 0.354 0.000
J38.4 Oedema of larynx
0.646 0.354 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.646 0.354 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.646 0.354 0.000
I05 Rheumatic mitral valve diseases
0.645 0.355 0.000
R76 Other abnormal immunological findings in serum
0.645 0.355 0.000
E27 Other disorders of adrenal gland
0.643 0.356 0.000
L10-L14 Bullous disorders
0.643 0.357 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.643 0.357 0.000
M79.7 Fibromyalgia
0.643 0.357 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.643 0.357 0.000
R77 Other abnormalities of plasma proteins
0.643 0.357 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.643 0.357 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.643 0.357 0.000
R71 Abnormality of red blood cells
0.643 0.357 0.000
M45 Ankylosing spondylitis
0.641 0.358 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.640 0.360 0.000
I07 Rheumatic tricuspid valve diseases
0.640 0.360 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.640 0.360 0.000
J35.1 Hypertrophy of tonsils
0.640 0.360 0.000
T33-T35 Frostbite
0.639 0.361 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.639 0.361 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.639 0.361 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.639 0.361 0.000
T00-T07 Injuries involving multiple body regions
0.639 0.361 0.000
S10-S19 Injuries to the neck
0.639 0.361 0.000
A49 Bacterial infection of unspecified site
0.638 0.362 0.000
D60-D64 Aplastic and other anaemias
0.638 0.362 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.638 0.362 0.000
R47.1 Dysarthria and anarthria
0.638 0.362 0.000
H33.5 Other retinal detachments
0.638 0.362 0.000
G30 Alzheimer's disease
0.638 0.362 0.000
R12 Heartburn
0.637 0.362 0.000
T79-T79 Certain early complications of trauma
0.637 0.363 0.000
D55-D59 Haemolytic anaemias
0.637 0.363 0.000
G44 Other headache syndromes
0.637 0.363 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.636 0.364 0.000
E00-E07 Disorders of thyroid gland
0.636 0.364 0.000
M17.9 Gonarthrosis, unspecified
0.635 0.365 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.634 0.366 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.634 0.366 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.634 0.366 0.000
I86 Varicose veins of other sites
0.634 0.366 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.634 0.366 0.000
I84.7 Unspecified thrombosed haemorrhoids
0.633 0.367 0.000
I84.3 External thrombosed haemorrhoids
0.633 0.367 0.000
I84.0 Internal thrombosed haemorrhoids
0.633 0.367 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.633 0.367 0.000
D50.9 Iron deficiency anaemia, unspecified
0.633 0.367 0.000
L82 Seborrhoeic keratosis
0.633 0.367 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.632 0.368 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.631 0.369 0.000
M76.6 Achilles tendinitis
0.631 0.369 0.000
J34 Other disorders of nose and nasal sinuses
0.630 0.370 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.630 0.370 0.000
E29 Testicular dysfunction
0.630 0.370 0.000
J43.8 Other emphysema
0.630 0.370 0.000
J43.2 Centrilobular emphysema
0.630 0.370 0.000
J43.1 Panlobular emphysema
0.630 0.370 0.000
J43.0 MacLeod's syndrome
0.630 0.370 0.000
I20 Angina pectoris
0.630 0.370 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.629 0.371 0.000
I80 Phlebitis and thrombophlebitis
0.629 0.371 0.000
K35-K38 Diseases of appendix
0.629 0.371 0.000
L72.0 Epidermal cyst
0.628 0.372 0.000
J33 Nasal polyp
0.628 0.372 0.000
Chapter V Mental and behavioural disorders
0.628 0.372 0.000
I09 Other rheumatic heart diseases
0.627 0.373 0.000
I06 Rheumatic aortic valve diseases
0.627 0.373 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.627 0.373 0.000
I08.0 Disorders of both mitral and aortic valves
0.626 0.374 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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