TreeWAS – Variant ID: rs727979

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E14.9 Without complications	0.041	0.959	0.000
T42.4 Benzodiazepines	0.034	0.966	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.034	0.966	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.034	0.966	0.000
T42.1 Iminostilbenes	0.029	0.971	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.024	0.975	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.024	0.975	0.000
T42.3 Barbiturates	0.024	0.975	0.000
T42.2 Succinimides and oxazolidinediones	0.024	0.975	0.000
T42.0 Hydantoin derivatives	0.024	0.975	0.000
I95.1 Orthostatic hypotension	0.000	0.977	0.023
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.022	0.978	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.022	0.978	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.021	0.979	0.000
D25.2 Subserosal leiomyoma of uterus	0.000	0.979	0.021
T40.4 Other synthetic narcotics	0.020	0.980	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.019	0.981	0.000
T40.2 Other opioids	0.019	0.981	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.018	0.982	0.000
T36 Poisoning by systemic antibiotics	0.017	0.983	0.000
S02.20 Fracture of nasal bones (closed)	0.017	0.983	0.000
T40.6 Other and unspecified narcotics	0.016	0.984	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.016	0.984	0.000
T43.6 Psychostimulants with abuse potential	0.016	0.984	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.016	0.984	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.016	0.984	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.016	0.984	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.015	0.984	0.000
T40.8 Lysergide [LSD]	0.015	0.984	0.000
T40.7 Cannabis (derivatives)	0.015	0.984	0.000
T40.5 Cocaine	0.015	0.984	0.000
T40.3 Methadone	0.015	0.984	0.000
T40.1 Heroin	0.015	0.984	0.000
T40.0 Opium	0.015	0.984	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.015	0.984	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.015	0.985	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.015	0.985	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.015	0.985	0.000
I95 Hypotension	0.000	0.985	0.015
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.015	0.985	0.000
I95.9 Hypotension, unspecified	0.000	0.985	0.015
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.014	0.986	0.000
T36.0 Penicillins	0.014	0.986	0.000
T43.9 Psychotropic drug, unspecified	0.014	0.986	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.014	0.986	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.014	0.986	0.000
E14 Unspecified diabetes mellitus	0.014	0.986	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.014	0.986	0.000
T36.9 Systemic antibiotic, unspecified	0.012	0.987	0.000
T36.8 Other systemic antibiotics	0.012	0.987	0.000
T36.7 Antifungal antibiotics, systemically used	0.012	0.987	0.000
T36.6 Rifamycins	0.012	0.987	0.000
T36.5 Aminoglycosides	0.012	0.987	0.000
T36.4 Tetracyclines	0.012	0.987	0.000
T36.3 Macrolides	0.012	0.987	0.000
T36.2 Chloramphenicol group	0.012	0.987	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.012	0.987	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.012	0.988	0.000
E14.8 With unspecified complications	0.012	0.988	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.012	0.988	0.000
I95.2 Hypotension due to drugs	0.000	0.988	0.012
T41.5 Therapeutic gases	0.011	0.988	0.000
T41.4 Anaesthetic, unspecified	0.011	0.988	0.000
T41.3 Local anaesthetics	0.011	0.988	0.000
T41.2 Other and unspecified general anaesthetics	0.011	0.988	0.000
T41.1 Intravenous anaesthetics	0.011	0.988	0.000
T41.0 Inhaled anaesthetics	0.011	0.988	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.011	0.988	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.011	0.988	0.000
T48.5 Anti-common-cold drugs	0.011	0.988	0.000
T48.4 Expectorants	0.011	0.988	0.000
T48.3 Antitussives	0.011	0.988	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.011	0.988	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.011	0.988	0.000
T48.0 Oxytocic drugs	0.011	0.988	0.000
T49.9 Topical agent, unspecified	0.011	0.988	0.000
T49.8 Other topical agents	0.011	0.988	0.000
T49.7 Dental drugs, topically applied	0.011	0.988	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.011	0.988	0.000
T49.5 Ophthalmological drugs and preparations	0.011	0.988	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.011	0.988	0.000
T49.3 Emollients, demulcents and protectants	0.011	0.988	0.000
T49.2 Local astringents and local detergents	0.011	0.988	0.000
T49.1 Antipruritics	0.011	0.988	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.011	0.988	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.011	0.989	0.000
T37.5 Antiviral drugs	0.011	0.989	0.000
T37.4 Anthelminthics	0.011	0.989	0.000
T37.3 Other antiprotozoal drugs	0.011	0.989	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.011	0.989	0.000
T37.1 Antimycobacterial drugs	0.011	0.989	0.000
T37.0 Sulphonamides	0.011	0.989	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.011	0.989	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.011	0.989	0.000
T47.7 Emetics	0.011	0.989	0.000
T47.6 Antidiarrhoeal drugs	0.011	0.989	0.000
T47.5 Digestants	0.011	0.989	0.000
T47.4 Other laxatives	0.011	0.989	0.000
T47.3 Saline and osmotic laxatives	0.011	0.989	0.000
T47.2 Stimulant laxatives	0.011	0.989	0.000
T47.0 Histamine H(2)-receptor antagonists	0.011	0.989	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.011	0.989	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.011	0.989	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.011	0.989	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.011	0.989	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.011	0.989	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.011	0.989	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.011	0.989	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.011	0.989	0.000
T44.0 Anticholinesterase agents	0.011	0.989	0.000
T50.8 Diagnostic agents	0.011	0.989	0.000
T50.7 Analeptics and opioid receptor antagonists	0.011	0.989	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.011	0.989	0.000
T50.5 Appetite depressants	0.011	0.989	0.000
T50.4 Drugs affecting uric acid metabolism	0.011	0.989	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.011	0.989	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.011	0.989	0.000
T50.1 Loop [high-ceiling] diuretics	0.011	0.989	0.000
T50.0 Mineralocorticoids and their antagonists	0.011	0.989	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.011	0.989	0.000
T38.9 Other and unspecified hormone antagonists	0.011	0.989	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.011	0.989	0.000
T38.7 Androgens and anabolic congeners	0.011	0.989	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.011	0.989	0.000
T38.5 Other oestrogens and progestogens	0.011	0.989	0.000
T38.4 Oral contraceptives	0.011	0.989	0.000
T38.2 Antithyroid drugs	0.011	0.989	0.000
T38.0 Glucocorticoids and synthetic analogues	0.011	0.989	0.000
T43.2 Other and unspecified antidepressants	0.011	0.989	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.011	0.989	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.011	0.989	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.010	0.989	0.000
I95.0 Idiopathic hypotension	0.000	0.990	0.010
T45.2 Vitamins, not elsewhere classified	0.010	0.990	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.010	0.990	0.000
T45.8 Other primarily systemic and haematological agents	0.010	0.990	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.010	0.990	0.000
T45.6 Fibrinolysis-affecting drugs	0.010	0.990	0.000
T45.4 Iron and its compounds	0.010	0.990	0.000
T45.3 Enzymes, not elsewhere classified	0.010	0.990	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.010	0.990	0.000
T45.0 Antiallergic and antiemetic drugs	0.010	0.990	0.000
E14.7 With multiple complications	0.010	0.990	0.000
E14.6 With other specified complications	0.010	0.990	0.000
E14.5 With peripheral circulatory complications	0.010	0.990	0.000
E14.2 Withrenal complications	0.010	0.990	0.000
E14.0 With coma	0.010	0.990	0.000
T38.1 Thyroid hormones and substitutes	0.010	0.990	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.010	0.990	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.010	0.990	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.010	0.990	0.000
T46.7 Peripheral vasodilators	0.010	0.990	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.010	0.990	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.010	0.990	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.010	0.990	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.010	0.990	0.000
E14.1 With ketoacidosis	0.010	0.990	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.009	0.990	0.000
T46.1 Calcium-channel blockers	0.009	0.991	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.009	0.991	0.000
E14.4 With neurological complications	0.009	0.991	0.000
T45.5 Anticoagulants	0.008	0.991	0.000
S02.2 Fracture of nasal bones	0.008	0.992	0.000
C90.0 Multiple myeloma	0.008	0.992	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.008	0.992	0.000
C92 Myeloid leukaemia	0.008	0.992	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.000	0.993	0.007
I95.8 Other hypotension	0.000	0.993	0.007
C92.1 Chronic myeloid leukaemia	0.007	0.993	0.000
H25.9 Senile cataract, unspecified	0.007	0.993	0.000
C90.2 Plasmacytoma, extramedullary	0.007	0.993	0.000
N32.9 Bladder disorder, unspecified	0.000	0.993	0.007
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.007	0.993	0.000
C92.0 Acute myeloid leukaemia	0.007	0.993	0.000
C92.4 Acute promyelocytic leukaemia	0.006	0.993	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.007	0.993	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.006	0.993	0.000
C81 Hodgkin's disease	0.006	0.994	0.000
S02.21 Fracture of nasal bones (open)	0.006	0.994	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.006	0.994	0.000
C90.3 Solitary plasmacytoma	0.006	0.994	0.000
E14.3 With ophthalmic complications	0.006	0.994	0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.000	0.994	0.006
S42.00 Fracture of clavicle (closed)	0.000	0.994	0.006
C90.1 Plasma cell leukaemia	0.006	0.994	0.000
C92.9 Myeloid leukaemia, unspecified	0.006	0.994	0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.006	0.994	0.000
C92.7 Other myeloid leukaemia	0.006	0.994	0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.006	0.994	0.000
C92.5 Acute myelomonocytic leukaemia	0.006	0.994	0.000
C92.3 Myeloid sarcoma	0.006	0.994	0.000
C92.2 Subacute myeloid leukaemia	0.006	0.994	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.006	0.994	0.000
C86 Other specified types of T/NK-cell lymphoma	0.005	0.994	0.000
C82.2 Large cell, follicular	0.005	0.994	0.000
C81.2 Mixed cellularity	0.005	0.994	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.005	0.995	0.000
C82.0 Small cleaved cell, follicular	0.005	0.995	0.000
O47.0 False labour before 37 completed weeks of gestation	0.000	0.995	0.005
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.005	0.995	0.000
C81.0 Lymphocytic predominance	0.005	0.995	0.000
C81.9 Hodgkin's disease, unspecified	0.005	0.995	0.000
C82.3 Follicular lymphoma grade IIIa	0.005	0.995	0.000
H43.3 Other vitreous opacities	0.005	0.995	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.005	0.995	0.000
C94 Other leukaemias of specified cell type	0.005	0.995	0.000
C93 Monocytic leukaemia	0.005	0.995	0.000
C95 Leukaemia of unspecified cell type	0.005	0.995	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.005	0.995	0.000
T39.4 Antirheumatics, not elsewhere classified	0.005	0.995	0.000
T39.2 Pyrazolone derivatives	0.005	0.995	0.000
C82.6 Cutaneous follicle centre lymphoma	0.005	0.995	0.000
C82.5 Diffuse follicle centre lymphoma	0.005	0.995	0.000
C82.4 Follicular lymphoma grade IIIb	0.005	0.995	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.005	0.995	0.000
C86.5 Angioimmunoblastic T-cell lymphoma	0.005	0.995	0.000
C81.1 Nodular sclerosis	0.005	0.995	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.005	0.995	0.000
C81.7 Other Hodgkin's disease	0.005	0.995	0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.005	0.995	0.000
C81.3 Lymphocytic depletion	0.005	0.995	0.000
Z51.1 Chemotherapy session for neoplasm	0.005	0.995	0.000
M21.24 Flexion deformity (Hand)	0.005	0.995	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.000	0.995	0.005
O47 False labour	0.000	0.995	0.004
K22.7 Barrett's oesophagus	0.000	0.995	0.005
T39.1 4-Aminophenol derivatives	0.004	0.996	0.000
M21.0 Valgus deformity, not elsewhere classified	0.004	0.996	0.000
C84.5 Other and unspecified T-cell lymphomas	0.004	0.996	0.000
M21.2 Flexion deformity	0.004	0.996	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.000	0.996	0.004
C84.4 Peripheral T-cell lymphoma	0.004	0.996	0.000
C86.6 Primary cutaneous CD30-positive T-cell proliferations	0.004	0.996	0.000
C86.4 Blastic NK-cell lymphoma	0.004	0.996	0.000
C86.3 Subcutaneous panniculitis-like T-cell lymphoma	0.004	0.996	0.000
C86.2 Enteropathy-type (intestinal) T-cell lymphoma	0.004	0.996	0.000
C86.1 Hepatosplenic T-cell lymphoma	0.004	0.996	0.000
C86.0 Extranodal NK/T-cell lymphoma, nasal type	0.004	0.996	0.000
C88 Malignant immunoproliferative diseases	0.004	0.996	0.000
C95.1 Chronic leukaemia of unspecified cell type	0.004	0.996	0.000
J92.9 Pleural plaque without asbestos	0.000	0.996	0.004
C84.9 Mature T/NK-cell lymphoma, unspecified	0.004	0.996	0.000
C84.8 Cutaneous T-cell lymphoma, unspecified	0.004	0.996	0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.004	0.996	0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.004	0.996	0.000
C84.3 Lymphoepithelioid lymphoma	0.004	0.996	0.000
C84.2 T-zone lymphoma	0.004	0.996	0.000
C84.1 Sezary's diease	0.004	0.996	0.000
C84.0 Mycosis fungoides	0.004	0.996	0.000
C93.9 Monocytic leukaemia, unspecified	0.004	0.996	0.000
C93.7 Other monocytic leukaemia	0.004	0.996	0.000
C93.3 Juvenile myelomonocytic leukaemia	0.004	0.996	0.000
C93.2 Subacute monocytic leukaemia	0.004	0.996	0.000
C93.1 Chronic monocytic leukaemia	0.004	0.996	0.000
C93.0 Acute monocytic leukaemia	0.004	0.996	0.000
C94.7 Other specified leukaemias	0.004	0.996	0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified	0.004	0.996	0.000
C94.5 Acute myelofibrosis	0.004	0.996	0.000
C94.4 Acute panmyelosis	0.004	0.996	0.000
C94.3 Mast cell leukaemia	0.004	0.996	0.000
C94.2 Acute megakaryoblastic leukaemia	0.004	0.996	0.000
C94.1 Chronic erythraemia	0.004	0.996	0.000
C94.0 Acute erythraemia and erythroleukaemia	0.004	0.996	0.000
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified	0.004	0.996	0.000
C96.8 Histiocytic sarcoma	0.004	0.996	0.000
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.004	0.996	0.000
C96.6 Unifocal Langerhans-cell histiocytosis	0.004	0.996	0.000
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis	0.004	0.996	0.000
C96.4 Sarcoma of dendritic cells (accessory cells)	0.004	0.996	0.000
C96.3 True histiocytic lymphoma	0.004	0.996	0.000
C96.2 Malignant mast cell tumour	0.004	0.996	0.000
C96.1 Malignant histiocytosis	0.004	0.996	0.000
C96.0 Letterer-Siwe disease	0.004	0.996	0.000
C95.7 Other leukaemia of unspecified cell type	0.004	0.996	0.000
C95.2 Subacute leukaemia of unspecified cell type	0.004	0.996	0.000
C95.0 Acute leukaemia of unspecified cell type	0.004	0.996	0.000
K22.1 Ulcer of oesophagus	0.000	0.996	0.004
M21.25 Flexion deformity (Pelvic region and thigh)	0.004	0.996	0.000
M21 Other acquired deformities of limbs	0.004	0.996	0.000
C91 Lymphoid leukaemia	0.003	0.996	0.000
T39.0 Salicylates	0.003	0.996	0.000
M21.26 Flexion deformity (Lower leg)	0.003	0.996	0.000
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.003	0.997	0.000
M21.08 Valgus deformity, not elsewhere classified (Other)	0.003	0.997	0.000
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.003	0.997	0.000
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.003	0.997	0.000
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.003	0.997	0.000
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.003	0.997	0.000
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.003	0.997	0.000
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.003	0.997	0.000
M21.27 Flexion deformity (Ankle and foot)	0.003	0.997	0.000
I83.0 Varicose veins of lower extremities with ulcer	0.000	0.997	0.003
M21.29 Flexion deformity (Site unspecified)	0.003	0.997	0.000
M21.28 Flexion deformity (Other)	0.003	0.997	0.000
M21.23 Flexion deformity (Forearm)	0.003	0.997	0.000
M21.22 Flexion deformity (Upper arm)	0.003	0.997	0.000
M21.21 Flexion deformity (Shoulder region)	0.003	0.997	0.000
M21.20 Flexion deformity (Multiple sites)	0.003	0.997	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.997	0.003
C88.9 Malignant immunoproliferative disease, unspecified	0.003	0.997	0.000
C88.7 Other malignant immunoproliferative diseases	0.003	0.997	0.000
C88.3 Immunoproliferative small intestinal disease	0.003	0.997	0.000
C88.2 Gamma heavy chain disease	0.003	0.997	0.000
C88.1 Alpha heavy chain disease	0.003	0.997	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.003	0.997	0.000
K22.5 Diverticulum of oesophagus, acquired	0.000	0.997	0.003
M81.40 Drug-induced osteoporosis (Multiple sites)	0.003	0.997	0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.003	0.997	0.000
K55.2 Angiodysplasia of colon	0.000	0.997	0.003
C83 Diffuse non-Hodgkin's lymphoma	0.003	0.997	0.000
C95.9 Leukaemia, unspecified	0.003	0.997	0.000
I83 Varicose veins of lower extremities	0.000	0.997	0.003
M21.8 Other specified acquired deformities of limbs	0.003	0.997	0.000
M79.79 Fibromyalgia (Site unspecified)	0.000	0.997	0.003
J01.9 Acute sinusitis, unspecified	0.003	0.997	0.000
C91.9 Lymphoid leukaemia, unspecified	0.003	0.997	0.000
K22 Other diseases of oesophagus	0.000	0.997	0.003
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.003	0.997	0.000
C15.5 Lower third of oesophagus	0.003	0.997	0.000
C91.5 Adult T-cell leukaemia	0.003	0.997	0.000
M21.4 Flat foot [pes planus] (acquired)	0.003	0.997	0.000
K22.9 Disease of oesophagus, unspecified	0.000	0.997	0.003
M21.7 Unequal limb length (acquired)	0.003	0.997	0.000
C91.0 Acute lymphoblastic leukaemia	0.003	0.997	0.000
M21.9 Acquired deformity of limb, unspecified	0.003	0.997	0.000
M21.1 Varus deformity, not elsewhere classified	0.003	0.997	0.000
I99 Other and unspecified disorders of circulatory system	0.000	0.997	0.003
M21.87 Other specified acquired deformities of limbs (Ankle and foot)	0.003	0.997	0.000
S42.0 Fracture of clavicle	0.000	0.997	0.003
C91.8 Mature B-cell leukaemia Burkitt-type	0.003	0.997	0.000
C91.7 Other lymphoid leukaemia	0.003	0.997	0.000
C91.6 Prolymphocytic leukaemia of T-cell type	0.003	0.997	0.000
C91.3 Prolymphocytic leukaemia	0.003	0.997	0.000
C91.2 Subacute lymphocytic leukaemia	0.003	0.997	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.997	0.003
I97.1 Other functional disturbances following cardiac surgery	0.000	0.997	0.003
I98 Other disorders of circulatory system in diseases classified elsewhere	0.000	0.997	0.003
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.003	0.997	0.000
R73.0 Abnormal glucose tolerance test	0.003	0.997	0.000
C83.7 Burkitt's tumour	0.003	0.997	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.000	0.997	0.003
I97.0 Postcardiotomy syndrome	0.000	0.997	0.003
C88.0 Waldenstrom's macroglobulinaemia	0.002	0.997	0.000
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.002	0.997	0.000
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.002	0.997	0.000
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.002	0.997	0.000
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.002	0.997	0.000
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.002	0.997	0.000
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.002	0.997	0.000
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar	0.002	0.997	0.000
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re	0.002	0.997	0.000
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)	0.002	0.997	0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.003	0.997	0.000
C83.6 Undifferentiated (diffuse)	0.002	0.997	0.000
C83.5 Lymphoblastic (diffuse)	0.002	0.997	0.000
C83.4 Immunoblastic (diffuse)	0.002	0.997	0.000
C83.2 Mixed small and large cell (diffuse)	0.002	0.997	0.000
C83.0 Small cell (diffuse)	0.003	0.997	0.000
H72.8 Other perforations of tympanic membrane	0.000	0.997	0.003
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.002	0.997	0.000
M21.88 Other specified acquired deformities of limbs-Other	0.002	0.997	0.000
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.002	0.997	0.000
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.002	0.997	0.000
M21.84 Other specified acquired deformities of limbs (Hand)	0.002	0.997	0.000
M21.83 Other specified acquired deformities of limbs (Forearm)	0.002	0.997	0.000
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.002	0.997	0.000
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.002	0.997	0.000
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.002	0.997	0.000
K22.4 Dyskinesia of oesophagus	0.000	0.997	0.003
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.002	0.997	0.000
K22.3 Perforation of oesophagus	0.000	0.997	0.002
J01.2 Acute ethmoidal sinusitis	0.002	0.997	0.000
M21.6 Other acquired deformities of ankle and foot	0.002	0.998	0.000
R22.0 Localised swelling, mass and lump, head	0.002	0.998	0.000
J91 Pleural effusion in conditions classified elsewhere	0.000	0.998	0.002
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.000	0.998	0.002
K25.7 Chronic without haemorrhage or perforation	0.000	0.998	0.002
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.002	0.998	0.000
M21.48 Flat foot [pes planus] (acquired)-Other	0.002	0.998	0.000
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.002	0.998	0.000
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.002	0.998	0.000
M21.44 Flat foot [pes planus] (acquired)-Hand	0.002	0.998	0.000
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.002	0.998	0.000
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.002	0.998	0.000
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.002	0.998	0.000
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.002	0.998	0.000
R73.9 Hyperglycaemia, unspecified	0.002	0.998	0.000
J01 Acute sinusitis	0.002	0.998	0.000
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)	0.002	0.998	0.000
M21.79 Unequal limb length (acquired) (Site unspecified)	0.002	0.998	0.000
M21.78 Unequal limb length (acquired)-Other	0.002	0.998	0.000
M21.77 Unequal limb length (acquired) (Ankle and foot)	0.002	0.998	0.000
M21.76 Unequal limb length (acquired) (Lower leg)	0.002	0.998	0.000
M21.74 Unequal limb length (acquired) (Hand)	0.002	0.998	0.000
M21.73 Unequal limb length (acquired) (Forearm)	0.002	0.998	0.000
M21.72 Unequal limb length (acquired) (Upper arm)	0.002	0.998	0.000
M21.71 Unequal limb length (acquired)-Shldr region	0.002	0.998	0.000
M21.70 Unequal limb length (acquired) (Multiple sites)	0.002	0.998	0.000
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M21.18 Varus deformity, not elsewhere classified (Other)	0.002	0.998	0.000
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
M21.14 Varus deformity, not elsewhere classified (Hand)	0.002	0.998	0.000
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.002	0.998	0.000
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.002	0.998	0.000
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
M21.99 Acquired deformity of limb, unspecified (Site unspecified)	0.002	0.998	0.000
M21.98 Acquired deformity of limb, unspecified-Other	0.002	0.998	0.000
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)	0.002	0.998	0.000
M21.96 Acquired deformity of limb, unspecified (Lower leg)	0.002	0.998	0.000
M21.95 Acquired deformity of limb, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M21.94 Acquired deformity of limb, unspecified (Hand)	0.002	0.998	0.000
M21.93 Acquired deformity of limb, unspecified (Forearm)	0.002	0.998	0.000
M21.92 Acquired deformity of limb, unspecified (Upper arm)	0.002	0.998	0.000
M21.91 Acquired deformity of limb, unspecified (Shoulder region)	0.002	0.998	0.000
M21.90 Acquired deformity of limb, unspecified (Multiple sites)	0.002	0.998	0.000
K22.2 Oesophageal obstruction	0.000	0.998	0.002
G93.8 Other specified disorders of brain	0.000	0.998	0.002
H72 Perforation of tympanic membrane	0.000	0.998	0.002
S42.01 Fracture of clavicle (open)	0.000	0.998	0.002
C25.9 Pancreas, unspecified	0.000	0.998	0.002
I97.2 Postmastectomy lymphoedema syndrome	0.000	0.998	0.002
K86.8 Other specified diseases of pancreas	0.000	0.998	0.002
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.002	0.998	0.000
C83.3 Large cell (diffuse)	0.002	0.998	0.000
C83.1 Small cleaved cell (diffuse)	0.002	0.998	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.002	0.998	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.000	0.998	0.002
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
I98.0 Cardiovascular syphilis	0.000	0.998	0.002
R73 Elevated blood glucose level	0.002	0.998	0.000
O69.2 Labour and delivery complicated by other cord entanglement	0.002	0.998	0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue	0.002	0.998	0.000
C91.4 Hairy-cell leukaemia	0.002	0.998	0.000
M21.3 Wrist or foot drop (acquired)	0.002	0.998	0.000
C15.4 Middle third of oesophagus	0.002	0.998	0.000
J33.9 Nasal polyp, unspecified	0.002	0.998	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.000	0.998	0.002
M81.4 Drug-induced osteoporosis	0.002	0.998	0.000
H10.9 Conjunctivitis, unspecified	0.002	0.998	0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.002	0.998	0.000
M21.68 Other acquired deformities of ankle and foot-Other	0.002	0.998	0.000
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.002	0.998	0.000
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.002	0.998	0.000
M21.64 Other acquired deformities of ankle and foot-Hand	0.002	0.998	0.000
M21.63 Other acquired deformities of ankle and foot-Forearm	0.002	0.998	0.000
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.002	0.998	0.000
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.002	0.998	0.000
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.002	0.998	0.000
J01.8 Other acute sinusitis	0.002	0.998	0.000
J01.4 Acute pansinusitis	0.002	0.998	0.000
J01.3 Acute sphenoidal sinusitis	0.002	0.998	0.000
J01.1 Acute frontal sinusitis	0.002	0.998	0.000
J01.0 Acute maxillary sinusitis	0.002	0.998	0.000
O69.9 Labour and delivery complicated by cord complication, unspecified	0.002	0.998	0.000
K22.0 Achalasia of cardia	0.000	0.998	0.002
H72.1 Attic perforation of tympanic membrane	0.000	0.998	0.002
K76.8 Other specified diseases of liver	0.000	0.998	0.002
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.002	0.998	0.000
I83.1 Varicose veins of lower extremities with inflammation	0.000	0.998	0.002
H54.7 Unspecified visual loss	0.000	0.998	0.002
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.002	0.998	0.000
C85.0 Lymphosarcoma	0.002	0.998	0.000
Z34.0 Supervision of normal first pregnancy	0.002	0.998	0.000
C15 Malignant neoplasm of oesophagus	0.002	0.998	0.000
J92 Pleural plaque	0.000	0.998	0.002
M81.49 Drug-induced osteoporosis (Site unspecified)	0.002	0.998	0.000
H72.2 Other marginal perforations of tympanic membrane	0.000	0.998	0.002
M21.39 Wrist or foot drop (acquired)-Site unspec	0.002	0.998	0.000
M21.38 Wrist or foot drop (acquired)-Other	0.002	0.998	0.000
M21.36 Wrist or foot drop (acquired)-Lower leg	0.002	0.998	0.000
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.002	0.998	0.000
M21.34 Wrist or foot drop (acquired) (Hand)	0.002	0.998	0.000
M21.33 Wrist or foot drop (acquired) (Forearm)	0.002	0.998	0.000
M21.32 Wrist or foot drop (acquired)-Upper arm	0.002	0.998	0.000
M21.31 Wrist or foot drop (acquired)-Shldr region	0.002	0.998	0.000
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.002	0.998	0.000
A87.9 Viral meningitis, unspecified	0.000	0.998	0.002
C85.7 Other specified types of non-Hodgkin's lymphoma	0.002	0.998	0.000
N92.0 Excessive and frequent menstruation with regular cycle	0.000	0.998	0.002
G61.0 Guillain-Barre syndrome	0.002	0.998	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.000	0.998	0.002
Z90.2 Acquired absence of lung [part of]	0.000	0.998	0.002
O47.9 False labour, unspecified	0.001	0.998	0.001
M81.48 Drug-induced osteoporosis (Other)	0.002	0.998	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.002	0.998	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.002	0.998	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.002	0.998	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.002	0.998	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.002	0.998	0.000
M81.42 Drug-induced osteoporosis (Upper arm)	0.002	0.998	0.000
M81.41 Drug-induced osteoporosis (Shoulder region)	0.002	0.998	0.000
U51.0 Not Previously admitted to a psyciatric hospital	0.000	0.998	0.002
C15.0 Cervical part of oesophagus	0.002	0.998	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.002	0.998	0.000
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.000	0.998	0.002
Z49.1 Extracorporeal dialysis	0.002	0.998	0.000
N42.8 Other specified disorders of prostate	0.000	0.998	0.002
C15.3 Upper third of oesophagus	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations